Miia Kivipelto
Professor
Professor in Neurogeriatrics
Institute of Public Health and Clinical Nutrition, School of Medicine, Faculty of Health Sciences
miia.kivipelto@uef.fi
Professor Miia Kivipelto, MD, PhD, is a specialist geriatrician with a PhD degree in Neurology, and a docent in Neurology and Neuroepidemiology.
She is the Chief Executive Officer of the Nordic Brain Network, a multidisciplinary research team of around 100 researchers and clinical staff based in Finland (University of Eastern Finland, THL), Sweden (Karolinska Institutet), and the United Kingdom (Imperial College London). Prof. Kivipelto is a member of a number of leading global dementia task forces, including the G8 Dementia Summit, OECD Mapping for big data in Alzheimer research, WHO ministerial meeting in Global actions against dementia and WHO dementia risk reduction guidelines working group.
Other appointments:
Professor of Clinical Geriatrics and senior geriatrician; Center for Alzheimer Research Karolinska Institutet; Stockholm, Sweden.
Director for Research & Development of Theme Aging; Karolinska University Hospital; Stockholm, Sweden.
Chair in Neuroepidemiology and Director of the Ageing Epidemiology Research Unit; Imperial College London; London, United Kingdom.
Projects
Files
1 itemsPublications
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A multimodal precision-prevention approach combining lifestyle intervention with metformin repurposing to prevent cognitive impairment and disability: the MET-FINGER randomised controlled trial protocol
Barbera, Mariagnese; Lehtisalo, Jenni; Perera, Dinithi; Aspö, Malin; Cross, Mary; De Jager Loots, Celeste A; Falaschetti, Emanuela; Friel, Naomi; Luchsinger, José A; Gavelin, Hanna Malmberg; Peltonen, Markku; Price, Geraint; Neely, Anna Stigsdotter; Thunborg, Charlotta; Tuomilehto, Jaakko; Mangialasche, Francesca; Middleton, Lefkos; Ngandu, Tiia; Solomon, Alina; Kivipelto, Miia; Adeleke, Seliat Adebanke; Arvidsson, Clara; Barton, Isobel; Bas, Mehmet; Cosby, Katrina; Crispin, Jennifer; Dunn, Lucy. 2024. Alzheimer's research and therapy. 16: . 23 -
A randomized, placebo-controlled trial of purified anthocyanins on cognitive function in individuals at elevated risk for dementia: Analysis of inflammatory biomarkers toward personalized interventions
Borda, Miguel German; Barreto, George E; Baldera, Jonathan Patricio; de Lucia, Chiara; Khalifa, Khadija; Bergland, Anne Katrine; Pola, Ilaria; Botero-Rodriguez, Felipe; Siow, Richard C; Kivipelto, Miia; Zetterberg, Henrik; Ashton, Nicholas J; Ballard, Clive; Aarsland, Dag. 2024. Experimental gerontology. 196: -
Alzheimer's disease genetic risk score and neuroimaging in the FINGER lifestyle trial
Saadmaan, Gazi; Dalmasso, Maria Carolina; Ramirez, Alfredo; Hiltunen, Mikko; Kemppainen, Nina; Lehtisalo, Jenni; Mangialasche, Francesca; Ngandu, Tiia; Rinne, Juha; Soininen, Hilkka; Stephen, Ruth; Kivipelto, Miia; Solomon, Alina. 2024. Alzheimer's & dementia. [Epub ahead of print 22 April 2024]: 1-6 -
Brain amyloid load, subjective memory complaints, and cognitive trajectories in older individuals at risk for dementia
Saadmaan, Gazi; Hall, Anette; Ngandu, Tiia; Kemppainen, Nina; Mangialasche, Francesca; Wittenberg, Gayle M; Matton, Anna; Rinne, Juha O; Kivipelto, Miia; Solomon, Alina. 2024. European journal of neurology. [First published: 12 August 2024]: -
CSF protein ratios with enhanced potential to reflect Alzheimer’s disease pathology and neurodegeneration
Mravinacová, Sára; Alanko, Vilma; Bergström, Sofia; Bridel, Claire; Pijnenburg, Yolande; Hagman, Göran; Kivipelto, Miia; Teunissen, Charlotte; Nilsson, Peter; Matton, Anna; Månberg, Anna. 2024. Molecular neurodegeneration. 19: . 15 -
Cardiometabolic multimorbidity, peripheral biomarkers, and dementia in rural older adults: The MIND‐China study
Liu, Cuicui; Liu, Rui; Tian, Na; Fa, Wenxin; Liu, Keke; Wang, Nan; Zhu, Min; Liang, Xiaoyan; Ma, Yixun; Ren, Yifei; Wang, Yongxiang; Cong, Lin; Tang, Shi; Vetrano, Davide Liborio; Ngandu, Tiia; Kivipelto, Miia; Hou, Tingting; Du, Yifeng; Qiu, Chengxuan. 2024. Alzheimer's & dementia. 20: 6133-6145 -
Cerebrovascular and Alzheimer’s disease biomarkers in dementia with Lewy bodies and other dementias
Rennie, Anna; Ekman, Urban; Shams, Sara; Rydén, Lina; Samuelsson, Jessica; Zettergren, Anna; Kern, Silke; Oppedal, Ketil; Blanc, Frédéric; Hort, Jakub; Garcia-Ptacek, Sara; Antonini, Angelo; Lemstra, Afina W; Padovani, Alessandro; Kramberger, Milica Gregoric; Rektorová, Irena; Walker, Zuzana; Snædal, Jón; Pardini, Matteo; Taylor, John-Paul; Bonanni, Laura; Granberg, Tobias; Aarsland, Dag; Skoog, Ingmar; Wahlund, Lars-Olof; Kivipelto, Miia; Westman, Eric; Ferreira, Daniel. 2024. Brain communications. 6: 1-15 -
Cognitive reserve, cortisol, and Alzheimer's disease biomarkers: A memory clinic study
Yerramalla, Manasa Shanta; Darin‐Mattsson, Alexander; Udeh‐Momoh, Chinedu T; Holleman, Jasper; Kåreholt, Ingemar; Aspö, Malin; Hagman, Göran; Kivipelto, Miia; Solomon, Alina; Marseglia, Anna; Sindi, Shireen. 2024. Alzheimer's & dementia. 20: 4486-4498 -
Daytime Sleepiness, Apnea, Neuroimaging Correlates and Cortisol Dysregulation in a Memory Clinic Cohort
Sørensen, C; Kåreholt, I; Kalpouzos, G; Udeh-Momoh, CT; Holleman, J; Aspö, M; Hagman, G; Spulber, G. Kivipelto, M; Solomon, A; Sindi, S. 2024. The Journal of prevention of Alzheimer's disease. [Epub ahead of print 18 July 2024]: 1-11 -
Diurnal cortisol, neuroinflammation, and neuroimaging visual rating scales in memory clinic patients
Holleman, Jasper; Daniilidou, Makrina; Kåreholt, Ingemar; Aspö, Malin; Hagman, Göran; Udeh-Momoh, Chinedu T; Spulber, Gabriela; Kivipelto, Miia; Solomon, Alina; Matton, Anna; Sindi, Shireen. 2024. Brain behavior and immunity. 118: 499-509 -
Effects of intensive lifestyle changes on the progression of mild cognitive impairment or early dementia due to Alzheimer’s disease: a randomized, controlled clinical trial
Ornish, Dean; Madison, Catherine; Kivipelto, Miia; Kemp, Colleen; McCulloch, Charles E.; Galasko, Douglas; Artz, Jon; Rentz, Dorene; Lin, Jue; Norman, Kim; Ornish, Anne; Tranter, Sarah; DeLamarter, Nancy; Wingers, Noel; Richling, Carra; Kaddurah-Daouk, Rima; Knight, Rob; McDonald, Daniel; Patel, Lucas; Verdin, Eric; E Tanzi, Rudolph; Arnold, Steven E. 2024. Alzheimer's research and therapy. 16: . 122 -
Evaluating the effect of rapamycin treatment in Alzheimer’s disease and aging using in vivo imaging: the ERAP phase IIa clinical study protocol
Svensson, Jonas E; Bolin, Martin; Thor, Daniel; Williams, Pete A; Brautaset, Rune; Carlsson, Marcus; Sörensson, Peder; Marlevi, David; Spin-Neto, Rubens; Probst, Monika; Hagman, Göran; Morén, Anton Forsberg; Kivipelto, Miia; Plavén-Sigray, Pontus. 2024. Bmc neurology. 24: . 111 -
Evaluation of Clinical Meaningfulness of Fortasyn Connect in Terms of “Time Saved”
Dickson, Samuel; Solomon, A; Kivipelto, M; Hartmann, T; van Hees, AMJ; Brownlee, A; Haaland, B; Mallinckrodt, CH; Hendrix, SB. 2024. The Journal of prevention of Alzheimer's disease. 11: 992-997 -
Feasibility of the “Preventing functional decline in acutely hospitalized older patients (PREV_FUNC)” study—A three-armed randomized controlled pilot trial
Sandberg, Linda; Boström, Anne-Marie; Hagströmer, Maria; Lindgren, Charlotte; Kivipelto, Miia; Sandlund, Christina; Welmer, Anna-Karin. 2024. PLoS ONE. 19: -
Frontoparietal atrophy trajectories in cognitively unimpaired elderly individuals using longitudinal Bayesian clustering
Lorenzon, G; Poulakis, K; Mohanty, R; Kivipelto, M; Eriksdotter, M; Ferreira, D; Westman, E. 2024. Computers in biology and medicine. 182: -
GOIZ ZAINDU study: a FINGER-like multidomain lifestyle intervention feasibility randomized trial to prevent dementia in Southern Europe
Tainta, Mikel; Ecay-Torres, Mirian; de Arriba, Maria; Barandiaran, Myriam; Otaegui-Arrazola, Ane; Iriondo, Ane; Garcia-Sebastian, Maite; Estanga, Ainara; Saldias, Jon; Clerigue, Montserrat; Gabilondo, Alazne; Ros, Naia; Mugica, Justo; Barandiaran, Aitziber; Mangialasche, Francesca; Kivipelto, Miia; Arrospide, Arantzazu; Mar, Javier; Martinez-Lage, Pablo; Aquizu, I; Arrondo, M A; Baztarrika, E; Etxeberria, L; García-Arrea, E; García-Domínguez, M; Imaz, E; Iparragirre, M; Iridoy, M; Larrea, A; Lóp. 2024. Alzheimer's research and therapy. 16: . 44 -
Gastrointestinal Diseases, Genetic Risk, and Incident Dementia: A Prospective Cohort Study in 352,463 Middle-Aged Adults
Yuan, Shuai; Dan, Lintao; Zhang, Yao; Wu, Jing; Zhao, Jianhui; Kivipelto, Miia; Chen, Jie; Ludvigsson, Jonas F; Li, Xue; Larsson, Susanna C. 2024. American journal of preventive medicine. 66: 516-525 -
Ikääntyneiden ihmisten kokemukset FINGER-elintapaintervention kuntosaliharjoittelusta ja liikuntatottumukset intervention jälkeen
Jylhä, Mia; Vesala, Riitta; Turunen, Katri; Ngandu, Tiia; Kivipelto, Miia; Havulinna, Satu; Kulmala, Jenni. 2024. Gerontologia. 38: 16-33 -
Integrating a multimodal lifestyle intervention with medical food in prodromal Alzheimer’s disease: the MIND-ADmini randomized controlled trial
Thunborg, Charlotta; Wang, Rui; Rosenberg, Anna; Sindi, Shireen; Andersen, Pia; Andrieu, Sandrine; Broersen, Laus M.; Coley, Nicola; Couderc, Celine; Duval, Celine Z.; Faxen-Irving, Gerd; Hagman, Göran; Hallikainen, Merja; Håkansson, Krister; Kekkonen, Eija; Lehtisalo, Jenni; Levak, Nicholas; Mangialasche, Francesca; Pantel, Johannes; Rydström, Anders; Stigsdotter-Neely, Anna; Wimo, Anders; Ngandu, Tiia; Soininen, Hilkka; Hartmann, Tobias; Solomon, Alina; Kivipelto, Miia. 2024. Alzheimer's research and therapy. 16: . 118 -
Lifestyle and behavioural changes in older adults during the Covid-19 pandemic are associated with subjective cognitive complaints
Zsuffa, Janos Andras; Katz, Sandor; Koszovacz, Vanda; Berente, Dalida Borbala; Kamondi, Anita; Csukly, Gabor; Mangialasche, Francesca; Rocha, Ana Sabsil Lopez; Kivipelto, Miia; Horvath, Andras Attila. 2024. Scientific reports. 14: . 2502 -
Multidomain Intervention for the Reversal of Cognitive Frailty Using a Personalized Approach (AGELESS Trial): Recruitment and Baseline Characteristics of Participants
Ibrahim, A. M.; Singh, D. K.A.; Ludin, A. F.M.; Subramaniam, P.; Ai-Vyrn, C.; Ibrahim, N.; Haron, H.; Safien, A. M.; Khalid, N. M.; Ponvel, P.; Fadzil, N. H.M.; Hanipah, J. M.; Mangialasche, F.; Kivipelto, M.; Shahar, Suzana. 2024. The Journal of prevention of Alzheimer's disease. [Epub ahead of print 13 June 2024]: 1-16 -
Neuroinflammation, cerebrovascular dysfunction and diurnal cortisol biomarkers in a memory clinic cohort: Findings from the Co-STAR study
Daniilidou, Makrina; Holleman, Jasper; Hagman, Göran; Kåreholt, Ingemar; Aspö, Malin; Brinkmalm, Ann; Zetterberg, Henrik; Blennow, Kaj; Solomon, Alina; Kivipelto, Miia; Sindi, Shireen; Matton, Anna. 2024. Translational psychiatry. 14: . 364 -
Nutrition guidance within a multimodal intervention improves diet quality in prodromal Alzheimer’s disease: Multimodal Preventive Trial for Alzheimer’s Disease (MIND-ADmini)
Levak, Nicholas; Lehtisalo, Jenni; Thunborg, Charlotta; Westman, Eric; Andersen, Pia; Andrieu, Sandrine; Broersen, Laus M.; Coley, Nicola; Hartmann, Tobias; Irving, Gerd Faxén; Mangialasche, Francesca; Ngandu, Tiia; Pantel, Johannes; Rosenberg, Anna; Sindi, Shireen; Soininen, Hilkka; Solomon, Alina; Wang, Rui; Kivipelto, Miia. 2024. Alzheimer's research and therapy. 16: . 147 -
Pivotal points in the science of dementia risk reduction
Kivipelto, Miia; Mangialasche, Francesca; Anstey, Kaarin J. 2024. The Lancet. 404: 501-503 -
Sleep disturbances and change in multiple cognitive domains among older adults: A multicentre study of five Nordic cohorts
Overton, Marieclaire; Skoog, Johan; Laukka, Erika J; Bodin, Timothy Hadarsson; Darin Mattsson, Alexander; Sjöberg, Linnea; Hofer, Scott M; Johansson, Lena; Kulmala, Jenni; Kivipelto, Miia; Solomon, Alina; Skoog, Ingmar; Kåreholt, Ingemar; Sindi, Shireen. 2024. Sleep. 47: 1-17 -
Social activities in multidomain dementia prevention interventions: insights from practice and a blueprint for the future
Bruinsma, Jeroen; Visser, Leonie NC; Abaci, Alara; Rosenberg, Anna; Diaz, Ana; Hanke, Sten; Crutzen, Rik; Mangialasche, Francesca; Kivipelto, Miia; Thunborg, Charlotta. 2024. Frontiers in psychiatry. 15: . 1386688 -
Temporal Muscle Thickness Predicts Mortality and Disability in Older Adults Diagnosed with Mild Dementia
Borda, Miguel German; Baldera, J Patricio; Patino-Hernandez, D; Westman, E; Pérez-Zepeda, M U; Tarazona-Santabalbina, F J; Wakabayashi, H; Arai, H; Kivipelto, M; Aarsland, D; NJ FINGER. 2024. Journal of frailty and aging. [Epub ahead of print 25 April 2024]: 1-7 -
The Australian National University Alzheimer's Disease Risk Index (ANU‐ADRI) score as a predictor for cognitive decline and potential surrogate outcome in the FINGER lifestyle randomized controlled trial
Hall, Anette; Barbera, Mariagnese; Lehtisalo, Jenni; Antikainen, Riitta; Huque, Hamidul; Laatikainen, Tiina; Ngandu, Tiia; Soininen, Hilkka; Stephen, Ruth; Strandberg, Timo; Kivipelto, Miia; Anstey, Kaarin J; Solomon, Alina. 2024. European journal of neurology. 31: -
The expectations and experiences of patients regarding the diagnostic workup at a specialized memory clinic: An interview study
Aspö, Malin; Sundell, Maria; Protsiv, Myroslava; Wiggenraad, Fleur; Rydén, Marie; Mangialasche, Francesca; Kivipelto, Miia; Visser, Leonie NC. 2024. Health expectations. 27: 1-10 -
Transitions: Living With Young‐Onset Alzheimer's Disease: A Qualitative Interview Study
Aspö, Malin; Visser, Leonie NC; Kivipelto, Miia; Boström, Anne‐Marie; Cronfalk, Berit Seiger. 2024. Health expectations. 27: 1-10 -
Validation, Deployment, and Real-World Implementation of a Modular Toolbox for Alzheimer’s Disease Detection and Dementia Risk Reduction: The AD-RIDDLE Project
Malzbender, K.; Barbarino, P.; Ferrell, P. Barkman; Bradshaw, A.; Brookes, A. J.; Díaz, C.; van der Flier, W. M.; Georges, J.; Hansson, O.; Hartmanis, M.; Jönsson, L.; Krishnan, R.; MacLeod, T.; Mangialasche, F.; Mecocci, P.; Minguillon, C.; Middleton, L.; Pla, S.; Sardi, S. P.; Schöll, M.; Suárez-Calvet, M.; Weidner, W.; Visser, P. J.; Zetterberg, H.; Bose, N.; Solomon, A.; Kivipelto, Miia; AD-RIDDLE Consortium. 2024. The Journal of prevention of Alzheimer's disease. 11: 329-338 -
27‐hydroxycholesterol promotes oligodendrocyte maturation: Implications for hypercholesterolemia‐associated brain white matter changes
Alanko, Vilma; Gaminde‐Blasco, Adhara; Quintela‐López, Tania; Loera‐Valencia, Raúl; Solomon, Alina; Björkhem, Ingemar; Cedazo‐Minguez, Angel; Maioli, Silvia; Tabacaru, Graziella; Latorre‐Leal, María; Matute, Carlos; Kivipelto, Miia; Alberdi, Elena; Sandebring‐Matton, Anna. 2023. Glia. 71: 1414-1428 -
Age-related differences in the functional topography of the locus coeruleus and their implications for cognitive and affective functions
Veréb, Dániel; Mijalkov, Mite; Canal-Garcia, Anna; Chang, Yu-Wei; Gomez-Ruiz, Emiliano; Gerboles, Blanca Zufiria; Kivipelto, Miia; Svenningsson, Per; Zetterberg, Henrik; Volpe, Giovanni; Betts, Matthew; Jacobs, Heidi IL; Pereira, Joana B. 2023. eLife. 12: . RP87188 -
Association of Sarcopenia and Its Defining Components with the Degree of Cognitive Impairment in a Memory Clinic Population
Larsson, Liss Elin; Wang, Rui; Cederholm, Tommy; Wiggenraad, Fleur; Rydén, Marie; Hagman, Göran; Hellénius, Mai-Lis; Kivipelto, Miia; Thunborg, Charlotta. 2023. Journal of Alzheimer's disease. 96: 777-788 -
Combined Evidence for a Long-Term, Clinical Slowing Effect of Multinutrient Intervention in Prodromal Alzheimer’s Disease: Post-Hoc Analysis of 3-Year Data from the LipiDiDiet Trial
Hendrix, Suzanne B; Soininen, H; Solomon, A; Visser, PJ; van Hees, AMJ; Counotte, DS; Nicodemus-Johnson, J; Dickson, SP; Blennow, K; Kivipelto, M; Hartmann, T; LipiDiDiet clinical study group. 2023. The Journal of prevention of Alzheimer's disease. 10: 464-470 -
Communication about diagnosis, prognosis, and prevention in the memory clinic: perspectives of European memory clinic professionals
Hendriksen, Heleen MA; van Gils, Aniek M; van Harten, Argonde C; Hartmann, Tobias; Mangialasche, Francesca; Kamondi, Anita; Kivipelto, Miia; Rhodius-Meester, Hanneke FM; Smets, Ellen MA; van der Flier, Wiesje M; Visser, Leonie NC. 2023. Alzheimer's research and therapy. 15: . 131 -
Dementia prevention in memory clinics: recommendations from the European task force for brain health services
Frisoni, Giovanni B.; Altomare, Daniele; Ribaldi, Federica; Villain, Nicolas; Brayne, Carol; Mukadam, Naaheed; Abramowicz, Marc; Barkhof, Frederik; Berthier, Marcelo; Bieler-Aeschlimann, Melanie; Blennow, Kaj; Brioschi Guevara, Andrea; Carrera, Emmanuel; Chételat, Gaël; Csajka, Chantal; Demonet, Jean-François; Dodich, Alessandra; Garibotto, Valentina; Georges, Jean; Hurst, Samia; Jessen, Frank; Kivipelto, Miia; Llewellyn, David J.; McWhirter, Laura; Milne, Richard; Minguillón, Carolina; Miniussi. 2023. The Lancet regional health – Europe. 26: -
Latin American Initiative for Lifestyle Intervention to Prevent Cognitive Decline (LatAm‐FINGERS): Study design and harmonization
Crivelli, Lucia; Calandri, Ismael Luis; Suemoto, Claudia Kimie; Salinas, Rosa María; Velilla, Lina Marcela; Yassuda, Mônica Sanches; Caramelli, Paulo; Lopera, Francisco; Nitrini, Ricardo; Sevlever, Gustavo Emilio; Sosa, Ana Luisa; Acosta, Daisy; Baietti, Ana María Charamelo; Cusicanqui, María Isabel; Custodio, Nilton; De Simone, Sergio Dansilio; Derio, Carolina Delgado; Duque‐Peñailillo, Lissette; Duran, Juan Carlos; Jiménez‐Velázquez, Ivonne Z.; Leon‐Salas, Jorge Mario; Bergamo, Yanina; Clarens. 2023. Alzheimer's & dementia. 19: 4046-4060 -
Life-course stress, cognition, and diurnal cortisol in memory clinic patients without dementia
Holleman, Jasper; Kåreholt, Ingemar; Aspö, Malin; Hagman, Göran; Udeh-Momoh, Chinedu T; Kivipelto, Miia; Solomon, Alina; Sindi, Shireen. 2023. Archives of gerontology and geriatrics. 2024; 119: -
Longitudinal study of Alzheimer's disease biomarkers, allostatic load, and cognition among memory clinic patients
Adedeji, Dickson O.; Holleman, Jasper; Juster, Robert-Paul; Udeh-Momoh, Chinedu T.; Kåreholt, Ingemar; Hagman, Göran; Aspö, Malin; Adagunodo, Sofia; Håkansson, Krister; Kivipelto, Miia; Solomon, Alina; Sindi, Shireen. 2023. Brain, behavior, & immunity : health. 28: -
Markers of vitamin B12 status in relation to cerebrospinal fluid biomarkers of Alzheimer's disease and cognitive performance
Hooshmand, Babak; Appold, Franziska; Fissler, Patrick; Perneczky, Robert; Otto, Markus; Tumani, Hayrettin; Kivipelto, Miia; von Arnim, Christine AF. 2023. Annals of neurology. 94: 223-231 -
Multimodal Precision Prevention - A New Direction in Alzheimer’s Disease
Barbera, M; Perera, D; Matton, A; Mangialasche, F; Rosenberg, A; Middleton, L; Ngandu, T; Solomon, A; Kivipelto, Miia. 2023. The Journal of prevention of Alzheimer's disease. 10: 718-728 -
Multimorbidity, cognitive phenotypes, and Alzheimer's disease plasma biomarkers in older adults: A population‐based study
Ren, Yifei; Li, Yuanjing; Tian, Na; Liu, Rui; Dong, Yi; Hou, Tingting; Liu, Cuicui; Han, Xiaolei; Han, Xiaodong; Wang, Lidan; Vetrano, Davide Liborio; Ngandu, Tiia; Marengoni, Alessandra; Kivipelto, Miia; Wang, Yongxiang; Cong, Lin; Du, Yifeng; Qiu, Chengxuan. 2023. Alzheimer's & dementia. 2024; 20: 1550-1561 -
Precision medicine in neurodegeneration: the IHI-PROMINENT project
Tate, Ashley; Suárez-Calvet, Marc; Ekelund, Mats; Eriksson, Sven; Eriksdotter, Maria; Van Der Flier, Wiesje M.; Georges, Jean; Kivipelto, Miia; Kramberger, Milica G.; Lindgren, Peter; López, Juan Domingo Gispert; Lötjönen, Jyrki; Persson, Sofie; Pla, Sandra; Solomon, Alina; Thurfjell, Lennart; Wimo, Anders; Winblad, Bengt; Jönsson, Linus; PROMINENT consortium. 2023. Frontiers in neurology. 14: . 1175922 -
Protective Alzheimer's disease-associated APP A673T variant predominantly decreases sAPPβ levels in cerebrospinal fluid and 2D/3D cell culture models
Wittrahm, Rebekka; Takalo, Mari; Kuulasmaa, Teemu; Mäkinen, Petra M; Mäkinen, Petri; Končarević, Saša; Fartzdinov, Vadim; Selzer, Stefan; Kokkola, Tarja; Antikainen, Leila; Martiskainen, Henna; Kemppainen, Susanna; Marttinen, Mikael; Jeskanen, Heli; Rostalski, Hannah; Rahunen, Eija; Kivipelto, Miia; Ngandu, Tiia; Natunen, Teemu; Lambert, Jean-Charles; Tanzi, Rudolph E; Kim, Doo Yeon; Rauramaa, Tuomas; Herukka, Sanna-Kaisa; Soininen, Hilkka; Laakso, Markku; Pike, Ian; Leinonen, Ville; Haapasalo, . 2023. Neurobiology of disease. 182: -
Recruitment of pre-dementia participants: main enrollment barriers in a longitudinal amyloid-PET study
Bader, Ilse; Bader, Ilona; Lopes Alves, Isadora; Vallez Garcia, David; Vellas, Bruno; Dubois, Bruno; Boada, Merce; Marquie, Marta; Altomare, Daniele; Scheltens, Philip; Vandenberghe, Rik; Hanseeuw, Bernard; Scholl, Michael; Frisoni, Giovanni B; Jessen, Frank; Nordberg, Agneta; Kivipelto, Miia; Ritchie, Craig W; Grau-Rivera, Oriol; Molinuevo, Jose Luis; Ford, Lisa; Stephens, Andrew; Gismondi, Rossella; Gispert, Juan Domingo; Farrar, Gill; Barkhof, Frederik; Visser, Pieter Jelle; Collij, Lyduine E. 2023. Alzheimer's research and therapy. 15: -
Response to “Comment on ‘Dementia prevention: The potential long-term cost-effectiveness of the FINGER prevention program’”
Wimo, Anders; Handels, Ron; Antikainen, Riitta; Eriksdotter, Maria; Jönsson, Linus; Knapp, Martin; Kulmala, Jenni; Laatikainen, Tiina; Lehtisalo, Jenni; Peltonen, Markku; Sköldunger, Anders; Soininen, Hilkka; Solomon, Alina; Timo Strandberg, T; Tuomilehto, Jaakko; Ngandu, Tiia; Kivipelto, Miia. 2023. Alzheimer's & dementia. 19: 4760-4763 -
Study design and methods: US study to protect brain health through lifestyle intervention to reduce risk (US POINTER)
Baker, Laura D; Snyder, Heather M; Espeland, Mark A; Whitmer, Rachel A; Kivipelto, Miia; Woolard, Nancy; Katula, Jeffrey; Papp, Kathryn V.; Ventrelle, Jennifer; Graef, Sarah; Hill, Marcus A; Rushing, Scott; Spell, Julia; Lovato, Laura; Felton, Deborah; Williams, Benjamin J; Ghadimi Nouran, Mina; Raman, Rema; Ngandu, Tiia; Solomon, Alina; Wilmoth, Sharon; Cleveland, Maryjo L; Williamson, Jeff D.; Lambert, Katherine L; Tomaszewski Farias, Sarah; Day, Claire E; Tangney, Christy C; Gitelman, Darren . 2023. Alzheimer's & dementia. 2024; 20: 769-782 -
Aivoterveyden edistäminen perusterveydenhuollossa vaatii vielä vahvistusta
Plaami, Ella; Lampio, Terhi; Pulkkinen, Pia; Hammar, Teija; Ngandu, Tiia; Roitto, Hanna-Maria; Kivipelto, Miia; Kulmala, Jenni. 2022. Gerontologia. 36: 420-425 -
Antioxidants and Dementia
Hooshmand, Babak; Kivipelto, Miia. 2022. Neurology. 98: 871-872 -
Association Between Cognition, Health Related Quality of Life, and Costs in a Population at Risk for Cognitive Decline
Janssen, Niels; Handels, Ron L.; Wimo, Anders; Antikainen, Riitta; Laatikainen, Tiina; Soininen, Hilkka; Strandberg, Timo; Tuomilehto, Jaakko; Kivipelto, Miia; Evers, Silvia M.A.A.; Verhey, Frans R.J.; Ngandu, Tiia. 2022. Journal of Alzheimer's disease. 89: 623-632 -
Associations of Depressive Symptoms and Cognition in the FINGER Trial: A Secondary Analysis of a Randomised Clinical Trial
Neuvonen, Elisa; Lehtisalo, Jenni; Ngandu, Tiia; Levälahti, Esko; Antikainen, Riitta; Hänninen, Tuomo; Laatikainen, Tiina; Lindström, Jaana; Paajanen, Teemu; Soininen, Hilkka; Strandberg, Timo; Tuomilehto, Jaakko; Kivipelto, Miia; Solomon, Alina. 2022. Journal of clinical medicine. 11: -
COVID-19 pandemic and mortality in nursing homes across USA and Europe up to October 2021
Aalto, Ulla L.; Pitkälä, Kaisu H.; Andersen-Ranberg, Karen; Bonin-Guillaume, Sylvie; Cruz-Jentoft, Alfonso Jose; Eriksdotter, Maria; Gordon, Adam L.; Gosch, Markus; Holmerova, Iva; Kautiainen, Hannu; Kivipelto, Miia; Macijauskiene, Jurate; O’Neill, Desmond; van den Noortgate, Nele; Ranhoff, Anette H.; Schols, Jos M. G. A.; Singler, Katrin; Stankunas, Mindaugas; Ouslander, Joseph G.. 2022. European geriatric medicine. 13: 705-709 -
Can dementia risk be reduced by following the American Heart Association's Life's Simple 7? A systematic review and dose-response meta-analysis
Wu, Jing; Xiong, Ying; Xia, Xin; Orsini, Nicola; Qiu, Chengxuan; Kivipelto, Miia; Rizzuto, Debora; Wang, Rui. 2022. Ageing research reviews. 2023; 83: -
Can exercise training teach us how to treat Alzheimer’s disease?
Huuha, Aleksi M; Norevik, Cecilie S.; Moreira, José Bianco N; Kobro-Flatmoen, Asgeir; Scrimgeour, Nathan; Kivipelto, Miia; Van Praag, Henriette; Ziaei, Maryam; Sando, Sigrid Botne; Wisløff, Ulrik; Tari, Atefe R. 2022. Ageing research reviews. 75: -
Changes in Brain-Health Related Modifiable Risk Factors in Older Adults After One Year of COVID-19-Restrictions
Waterink, Lisa; Bakker, Els D.; Visser, Leonie N. C.; Mangialasche, Francesca; Kivipelto, Miia; Deckers, Kay; Köhler, Sebastian; Sikkes, Sietske A. M.; Prins, Niels D.; Scheltens, Philip; Flier, Wiesje M. van der; Zwan, Marissa D.. 2022. Frontiers in psychiatry. 13: -
Changes in cognitive functioning after COVID‐19: A systematic review and meta‐analysis
Crivelli, Lucia; Palmer, Katie; Calandri, Ismael; Guekht, Alla; Beghi, Ettore; Carroll, William; Frontera, Jennifer; García‐Azorín, David; Westenberg, Erica; Winkler, Andrea Sylvia; Mangialasche, Francesca; Allegri, Ricardo F; Kivipelto, Miia. 2022. Alzheimer's & dementia. 18: 1047-1066 -
Cognitive Performance at Time of AD Diagnosis: A Clinically Augmented Register-Based Study
Alenius, Minna; Hokkanen, Laura; Koskinen, Sanna; Hallikainen, Ilona; Hänninen, Tuomo; Karrasch, Mira; Raivio, Minna M.; Laakkonen, Marja-Liisa; Krüger, Johanna; Suhonen, Noora-Maria; Kivipelto, Miia; Ngandu, Tiia. 2022. Frontiers in psychology. 13: . 901945 -
Cortisol, cognition and Alzheimer’s disease biomarkers among memory clinic patients
Holleman, Jasper; Adagunodo, Sofia; Kåreholt, Ingemar; Hagman, Göran; Aspö, Malin; Udeh-Momoh, Chinedu T; Solomon, Alina; Kivipelto, Miia; Sindi, Shireen. 2022. BMJ neurology open. 4: -
Dementia Risk Scores and Their Role in the Implementation of Risk Reduction Guidelines
Anstey, Kaarin J; Zheng, Lidan; Peters, Ruth; Kootar, Scherazad; Barbera, Mariagnese; Stephen, Ruth; Dua, Tarun; Chowdhary, Neerja; Solomon, Alina; Kivipelto, Miia. 2022. Frontiers in neurology. 12: . 765454 -
Dementia prevention: The potential long-term cost-effectiveness of the FINGER prevention program
Wimo, Anders; Handels, Ron; Antikainen, Riitta; Eriksdotter, Maria; Jönsson, Linus; Knapp, Martin; Kulmala, Jenni; Laatikainen, Tiina; Lehtisalo, Jenni; Peltonen, Markku; Sköldunger, Anders; Soininen, Hilkka; Solomon, Alina; Strandberg, Timo; Tuomilehto, Jaakko; Ngandu, Tiia; Kivipelto, Miia. 2022. Alzheimer's & dementia. [First published: 16 July 2022]: 1-10 -
Education-Based Cutoffs for Cognitive Screening of Alzheimer’s Disease
Alenius, Minna; Ngandu, Tiia; Koskinen, Sanna; Hallikainen, Ilona; Hänninen, Tuomo; Karrasch, Mira; Kivipelto, Miia; Raivio, Minna M.; Laakkonen, Marja-Liisa; Krüger, Johanna; Suhonen, Noora-Maria; Hokkanen, Laura. 2022. Dementia and geriatric cognitive disorders. 51: 42-55 -
Effects of Physical and Cognitive Training on Falls and Concern About Falling in Older Adults: Results From a Randomized Controlled Trial
Turunen, Katri M.; Tirkkonen, Anna; Savikangas, Tiina; Hanninen, Tuomo; Alen, Markku; Fielding, Roger A.; Kivipelto, Miia; Neely, Anna Stigsdotter; Tormakangas, Timo; Sipila, Sarianna. 2022. Journals of gerontology series a: biological sciences and medical sciences. 77: 1430-1437 -
Experiences of Active Everyday Life Among Persons with Prodromal Alzheimer’s Disease: A Qualitative Study
Fallahpour, Mandana; Fritz, Heather; Thunborg, Charlotta; Akenine, Ulrika; Kivipelto, Miia. 2022. Journal of multidisciplinary healthcare. 15: 1921-1932 -
Experiences of Participation in a Multimodal Preventive Trial MIND-AD MINI Among Persons with Prodromal Alzheimer’s Disease: A Qualitative Study
Akenine, Ulrika; Thunborg, Charlotta; Kivipelto, Miia; Fallahpour, Mandana. 2022. Journal of multidisciplinary healthcare. 15: 219-234 -
Factors Predicting Engagement of Older Adults With a Coach-Supported eHealth Intervention Promoting Lifestyle Change and Associations Between Engagement and Changes in Cardiovascular and Dementia Risk: Secondary Analysis of an 18-Month Multinational Randomized Controlled Trial
Coley, Nicola; Andre, Laurine; Hoevenaar-Blom, Marieke P; Ngandu, Tiia; Beishuizen, Cathrien; Barbera, Mariagnese; van Wanrooij, Lennard; Kivipelto, Miia; Soininen, Hilkka; van Gool, Willem; Brayne, Carol; Moll van Charante, Eric; Richard, Edo; Andrieu, Sandrine; HATICE study group; PRODEMOS study group. 2022. Journal of medical internet research. 24: -
Liikkumisen kannustimet muistisairauksien riskiryhmään kuuluvilla ikääntyneillä
Anttila, Pia; Ngandu, Tiia; Häkkinen, Arja; Lehtisalo, Jenni; Kivipelto, Miia; Kulmala, Jenni. 2022. Gerontologia. 36: 4-15 -
Mechanisms Underlying Non-Pharmacological Dementia Prevention Strategies: A Translational Perspective
Alanko, V; Udeh-Momoh, C; Kivipelto, M; Sandebring-Matton, A. 2022. The Journal of prevention of Alzheimer's disease. 9: 3-11 -
Memory clinic clinicians’ preferences and needs for communication with patients: A multi-national survey study from EU-FINGERS & LETHE projects
Hendriksen, Heleen MA; van Gils, Aniek M; Kivipelto, Miia; Mangialasche, Francesca; Meester, Hanneke FM Rhodius; Smets, Ellen MA; van der Flier, Wiesje M; Visser, Leonie NC. 2022. Alzheimer's & dementia -
Metabolome-wide association study on ABCA7 indicates a role of ceramide metabolism in Alzheimer’s disease
Dehghan, Abbas; Pinto, Rui Climaco; Karaman, Ibrahim; Huang, Jian; Durainayagam, Brenan R.; Ghanbari, Mohsen; Nazeer, Areesha; Zhong, Qi; Liggi, Sonia; Whiley, Luke; Mustafa, Rima; Kivipelto, Miia; Solomon, Alina; Ngandu, Tiia; Kanekiyo, Takahisa; Aikawa, Tomonori; Radulescu, Carola I.; Barnes, Samuel J.; Graça, Gonçalo; Chekmeneva, Elena; Camuzeaux, Stephane; Lewis, Matthew R.; Kaluarachchi, Manuja R.; Ikram, M. Arfan; Holmes, Elaine; Tzoulaki, Ioanna; Matthews, Paul M.; Griffin, Julian L.; Ell. 2022. Proceedings of the National Academy of Sciences of the United States of America. 119: . e2206083119 -
Multidomain interventions for risk reduction and prevention of cognitive decline and dementia: current developments
Röhr, Susanne; Kivipelto, Miia; Mangialasche, Francesca; Ngandu, Tiia; Riedel-Heller, Steffi G. 2022. Current opinion in psychiatry. 35: 285-292 -
Multimodal Preventive Trial for Alzheimer’s Disease: MIND-ADmini Pilot Trial Study Design and Progress
Sindi, S; Thunborg, C; Rosenberg, A; Andersen, P; Andrieu, S; Broersen, LM; Coley, N; Couderc, C; Duval, CZ; Faxen-Irving, G; Hagman, G; Hallikainen, M; Håkansson, K; Lehtisalo, J; Levak, N; Mangialasche, F; Pantel, J; Kekkonen, E; Rydström, A; Stigsdotter-Neely, A; Wimo, A; Ngandu, T; Soininen, H; Hartmann, T; Solomon, A; Kivipelto, M. 2022. The Journal of prevention of Alzheimer's disease. 9: 30-39 -
New insights into the genetic etiology of Alzheimer’s disease and related dementias
Bellenguez, Céline; Küçükali, Fahri; Jansen, Iris E.; Kleineidam, Luca; Moreno-Grau, Sonia; Amin, Najaf; Naj, Adam C.; Campos-Martin, Rafael; Grenier-Boley, Benjamin; Andrade, Victor; Holmans, Peter A.; Boland, Anne; Damotte, Vincent; van der Lee, Sven J.; Costa, Marcos R.; Kuulasmaa, Teemu; Yang, Qiong; de Rojas, Itziar; Bis, Joshua C.; Yaqub, Amber; Prokic, Ivana; Chapuis, Julien; Ahmad, Shahzad; Giedraitis, Vilmantas; Aarsland, Dag; Garcia-Gonzalez, Pablo; Abdelnour, Carla; Alarcón-Martín, Em. 2022. Nature genetics. 54: 412-436 -
Occupational complexity and cognition in the FINGER multidomain intervention trial
Rydström, Anders; Darin‐Mattsson, Alexander; Kåreholt, Ingemar; Ngandu, Tiia; Lehtisalo, Jenni; Solomon, Alina; Antikainen, Riitta; Bäckman, Lars; Hänninen, Tuomo; Laatikainen, Tiina; Levälahti, Esko; Lindström, Jaana; Paajanen, Teemu; Havulinna, Satu; Peltonen, Markku; Sindi, Shireen; Soininen, Hilkka; Neely, Anna Stigsdotter; Strandberg, Timo; Tuomilehto, Jaakko; Kivipelto, Miia; Mangialasche, Francesca. 2022. Alzheimer's & dementia. 18: 2438-2447 -
Psychosocial determinants for adherence to a healthy lifestyle and intervention participation in the FINGER trial: an exploratory analysis of a randomised clinical trial
Neuvonen, Elisa; Lehtisalo, Jenni; Solomon, Alina; Antikainen, Riitta; Havulinna, Satu; Hänninen, Tuomo; Laatikainen, Tiina; Lindström, Jaana; Rautio, Nina; Soininen, Hilkka; Strandberg, Timo; Tuomilehto, Jaakko; Kivipelto, Miia; Ngandu, Tiia. 2022. Aging clinical and experimental research. 34: 1793-1805 -
Reducing the Risk of Cognitive Decline and Dementia: WHO Recommendations
Chowdhary, Neerja; Barbui, Corrado; Anstey, Kaarin J.; Kivipelto, Miia; Barbera, Mariagnese; Peters, Ruth; Zheng, Lidan; Kulmala, Jenni; Stephen, Ruth; Ferri, Cleusa P.; Joanette, Yves; Wang, Huali; Comas-Herrera, Adelina; Alessi, Charles; Suharya (Dy), Kusumadewi; Mwangi, Kibachio J.; Petersen, Ronald C.; Motala, Ayesha A.; Mendis, Shanthi; Prabhakaran, Dorairaj; Bibi Mia Sorefan, Ameenah; Dias, Amit; Gouider, Riadh; Shahar, Suzana; Ashby-Mitchell, Kimberly; Prince, Martin; Dua, Tarun. 2022. Frontiers in neurology. 12: . 765584 -
Serum Thioredoxin-80 is associated with age, ApoE4, and neuropathological biomarkers in Alzheimer’s disease: a potential early sign of AD
Goikolea, Julen; Gerenu, Gorka; Daniilidou, Makrina; Mangialasche, Francesca; Mecocci, Patrizia; Ngandu, Tiia; Rinne, Juha; Solomon, Alina; Kivipelto, Miia; Cedazo-Minguez, Angel; Sandebring-Matton, Anna; Maioli, Silvia. 2022. Alzheimer's research and therapy. 14: . 37 -
Trajectories of cognitive decline and dementia development: A 12‐year longitudinal study
Payton, Nicola M; Marseglia, Anna; Grande, Giulia; Fratiglioni, Laura; Kivipelto, Miia; Bäckman, Lars; Laukka, Erika J. 2022. Alzheimer's & dementia. [First published: 17 June 2022]: 1-11 -
Trials and Treatments for Vascular Brain Health: Risk Factor Modification and Cognitive Outcomes
Kivipelto, Miia; Palmer, Katie; Hoang, Tina D; Yaffe, Kristine. 2022. Stroke. 53: 444-456 -
β-Amyloid, Tau, Neurodegeneration Classification and Eligibility for Anti-amyloid Treatment in a Memory Clinic Population
Rosenberg, Anna; Öhlund-Wistbacka, Ulf; Hall, Anette; Bonnard, Alexandre; Hagman, Göran; Rydén, Marie; Thunborg, Charlotta; Wiggenraad, Fleur; Sandebring-Matton, Anna; Solomon, Alina; Kivipelto, Miia. 2022. Neurology. 99: 1-35 -
27-Hydroxycholesterol, cognition, and brain imaging markers in the FINGER randomized controlled trial
Sandebring-Matton, Anna; Goikolea, Julen; Björkhem, Ingemar; Paternain, Laura; Kemppainen, Nina; Laatikainen, Tiina; Ngandu, Tiia; Rinne, Juha; Soininen, Hilkka; Cedazo-Minguez, Angel; Solomon, Alina; Kivipelto, Miia. 2021. Alzheimer's research and therapy. 13: 56 -
A competing risk joint model for dealing with different types of missing data in an intervention trial in prodromal Alzheimer's disease
Swinkels, Sophie HN; Soininen, Hilkka; Kivipelto, Miia; Hartmann, Tobias; Rizopoulos, Dimitris. 2021. Alzheimer's research and therapy. 13: 63 -
Alzheimer's disease
Scheltens, Philip; De Strooper, Bart; Kivipelto, Miia; Holstege, Henne; Chételat, Gael; Teunissen, Charlotte E; Cummings, Jeffrey; van der Flier, Wiesje M. 2021. The Lancet. 397: 1577-1590 -
Blood Derived Amyloid Biomarkers for Alzheimer's Disease Prevention
Udeh-Momoh, C; Zheng, B; Sandebring-Matton, A; Novak, G; Kivipelto, M; Jönsson, L; Middleton, L; Alzheimer's Disease Neuroimaging Initiative. 2021. The Journal of prevention of Alzheimer's disease. 2022; 9: 12-21 -
Change in CAIDE Dementia Risk Score and neuroimaging biomarkers during a 2-year multidomain lifestyle randomized controlled trial: results of a post-hoc subgroup analysis
Stephen, Ruth; Ngandu, Tiia; Liu, Yawu; Peltonen, Markku; Antikainen, Riitta; Kemppainen, Nina; Laatikainen, Tiina; Lötjönen, Jyrki; Rinne, Juha; Strandberg, Timo; Tuomilehto, Jaakko; Vanninen, Ritva; Soininen, Hilkka; Kivipelto, Miia; Solomon, Alina. 2021. Journals of gerontology series a: biological sciences and medical sciences. 76: 1407-1414 -
Changes in Lifestyle, Behaviors, and Risk Factors for Cognitive Impairment in Older Persons During the First Wave of the Coronavirus Disease 2019 Pandemic in Finland: Results From the FINGER Study
Lehtisalo, Jenni; Palmer, Katie; Mangialasche, Francesca; Solomon, Alina; Kivipelto, Miia; Ngandu, Tiia. 2021. Frontiers in psychiatry. 12: 624125 -
Common variants in Alzheimer's disease and risk stratification by polygenic risk scores
de Rojas, I; Moreno-Grau, S; Tesi, N; Grenier-Boley, B; Andrade, V; Jansen, IE; Pedersen, NL; Stringa, N; Zettergren, A; Hernández, I; Montrreal, L; Antúnez, C; Antonell, A; Tankard, RM; Bis, JC; Sims, R; Bellenguez, C; Quintela, I; González-Perez, A; Calero, M; et al; [incl. Haapasalo, A; Soininen, H; Lehtisalo, J; Kivipelto, M; Kuulasmaa, T; Hiltunen, M]. 2021. Nature communications. 12: 3417 -
Dementia research in 2020: moving forward despite the COVID-19 pandemic
Kivipelto, Miia; Mangialasche, Francesc. 2021. The Lancet Neurology. 20: 3-5 -
Development of the First WHO Guidelines for Risk Reduction of Cognitive Decline and Dementia: Lessons Learned and Future Directions
Stephen, Ruth; Barbera, Mariagnese; Peters, Ruth; Ee, Nicole; Zheng, Lidan; Lehtisalo, Jenni; Kulmala, Jenni; Håkansson, Krister; Chowdhary, Neerja; Dua, Tarun; Solomon, Alina; Anstey, Kaarin J; Kivipelto, Miia. 2021. Frontiers in neurology. 12: 763573 -
Digital Screening for Cognitive Impairment - A Proof of Concept Study
Bloniecki, Victor; Hagman, G; Ryden, M; Kivipelto, M. 2021. The Journal of prevention of Alzheimer's disease. 8: 127-134 -
Editorial: Cognitive, Psychological, and Psychiatric Consequences of the Coronavirus (COVID-19) Pandemic in the Population of Older Persons With Cognitive Impairment, Dementia, and/or Neuropsychiatric Disorders
Palmer, Katie; Kivipelto, Miia; Gianni, Walter; Banaj, Nerisa; Spalletta, Gianfranco. 2021. Frontiers in psychiatry. 12: 748963 -
Effect of a Multidomain Lifestyle Intervention on Estimated Dementia Risk
Solomon, Alina; Handels, Ron; Wimo, Anders; Antikainen, Riitta; Laatikainen, Tiina; Levälahti, Esko; Peltonen, Markku; Soininen, Hilkka; Strandberg, Timo; Tuomilehto, Jaakko; Kivipelto, Miia; Ngandu, Tiia. 2021. Journal of Alzheimer's disease. 82: 1461-1466 -
Effects of physical and cognitive training on gait speed and cognition in older adults: A randomized controlled trial
Sipilä, Sarianna; Tirkkonen, Anna; Savikangas, Tiina; Hänninen, Tuomo; Laukkanen, Pia; Alen, Markku; Fielding, Roger A; Kivipelto, Miia; Kulmala, Jenni; Rantanen, Taina; Sihvonen, Sanna E; Sillanpää, Elina; Stigsdotter Neely, Anna; Törmäkangas, Timo. 2021. Scandinavian journal of medicine and science in sports. 31: 1518-1533 -
Exercise, diet, and cognition in a 4-year randomized controlled trial: Dose-Responses to Exercise Training (DR's EXTRA)
Komulainen, Pirjo; Tuomilehto, Jaakko; Savonen, Kai; Männikkö, Reija; Hassinen, Maija; Lakka, Timo A; Hänninen, Tuomo; Kiviniemi, Vesa; Jacobs, David R; Kivipelto, Miia; Rauramaa, Rainer. 2021. American journal of clinical nutrition. 113: 1428-1439 -
Facilitators and barriers to implementing lifestyle intervention programme to prevent cognitive decline
Kulmala, J; Rosenberg, A; Ngandu, T; Hemiö, K; Tenkula, T; Hyytiä, A; Vienola, M; Huhtamäki-Kuoppala, M; Saarinen, A; Korkki, S; Laatikainen, T; Solomon, A; Kivipelto, M. 2021. European journal of public health. 31: 816-822 -
Health, Lifestyle, and Psycho-Social Determinants of Poor Sleep Quality During the Early Phase of the COVID-19 Pandemic: A Focus on UK Older Adults Deemed Clinically Extremely Vulnerable
Udeh-Momoh, Chinedu T.; Watermeyer, Tamlyn; Sindi, Shireen; Giannakopoulou, Parthenia; Robb, Catherine E.; Ahmadi-Abhari, Sara; Zheng, Bang; Waheed, Amina; McKeand, James; Salman, David; Beaney, Thomas; de Jager Loots, Celeste A.; Price, Geraint; Atchison, Christina; Car, Josip; Majeed, Azeem; McGregor, Alison. H.; Kivipelto, Miia; Ward, Helen; Middleton, Lefkos T.. 2021. Frontiers in public health. 9: 753964 -
How can dementia and disability be prevented in older adults: Where are we today and where are we going?
Lisko, Inna; Kulmala, Jenni; Annetorp, Martin; Ngandu, Tiia; Mangialasche, Francesca; Kivipelto, Miia. 2021. Journal of internal medicine. 289: 807-830 -
Impact of the COVID-19 pandemic on statistical design and analysis plans for multidomain intervention clinical trials: Experience from World-Wide FINGERS
Röhr, Susanne; Arai, Hidenori; Mangialasche, Francesca; Matsumoto, Nanae; Peltonen, Markku; Raman, Rema; Riedel-Heller, Steffi G.; Sakurai, Takashi; Snyder, Heather M.; Sugimoto, Taiki; Carrillo, Maria; Kivipelto, Miia; Espeland, Mark A. 2021. Alzheimer's & dementia : Translational research & clinical interventions. 7: e12143 -
Muistisairaudet
Lehtisalo, Jenni; Kivipelto, Miia; Ngandu, Tiia; Eskelinen, Marjo; Soininen, Hilkka. Teoksessa: Mutanen, Marja; Niinikoski, Harri; Schwab, Ursula; Uusitupa, Matti(toim.) , 2021. Ravitsemustiede (8. uud. painos). s. 461-466. Duodecim -
Multidomain interventions: state-of-the-art and future directions for protocols to implement precision dementia risk reduction. A user manual for Brain Health Services-part 4 of 6
Solomon, Alina; Stephen, Ruth; Altomare, Daniele; Carrera, Emmanuel; Frisoni, Giovanni B.; Kulmala, Jenni; Molinuevo, José Luis; Nilsson, Peter; Ngandu, Tiia; Ribaldi, Federica; Vellas, Bruno; Scheltens, Philip; Kivipelto, Miia; European Task Force for Brain Health Services. 2021. Alzheimer's research and therapy. 13: 171 -
Personal Social Networks of Community-Dwelling Oldest Old During the Covid-19 Pandemic - A Qualitative Study
Kulmala, Jenni; Tiilikainen, Elisa; Lisko, Inna; Ngandu, Tiia; Kivipelto, Miia; Solomon, Alina. 2021. Frontiers in public health. 9: 770965 -
Quantifying dementia prevention potential in the FINGER randomized controlled trial using the LIBRA prevention index.
Deckers, Kay; Köhler, Sebastian; Ngandu, Tiia; Antikainen, Riitta; Laatikainen, Tiina; Soininen, Hilkka; Strandberg, Timo; Verhey, Frans; Kivipelto, Miia; Solomon, Alina. 2021. Alzheimer's & dementia. 17: 1205-1212 -
Red Cell Distribution Width and Dementia Among Rural-Dwelling Older Adults: The MIND-China Study
Jiang, Z; Han, X; Wang, Y; Hou, T; Cong, L; Tang, S; Han, X; Ngandu, T; Kivipelto, M; Winblad, B; Launer, LJ; Du, Y; Qiu, C. 2021. Journal of Alzheimer's disease. 83: 1187-1198 -
Research diagnostic criteria for Alzheimer's disease: findings from the LipiDiDiet randomized controlled trial
Rosenberg, Anna; Solomon, Alina; Soininen, Hilkka; Visser, Pieter Jelle; Blennow, Kaj; Hartmann, Tobias; Kivipelto, Miia; on behalf of the LipiDiDiet clinical study group [incl. Hallikainen, Ilona; Hallikainen, Merja; Helisalmi, Seppo; Lappalainen, Tarja; Liu, Yawu; Paajanen, Teemu]. 2021. Alzheimer's research and therapy. 13: 64 -
Serum proBDNF Is Associated With Changes in the Ketone Body ß-Hydroxybutyrate and Shows Superior Repeatability Over Mature BDNF: Secondary Outcomes From a Cross-Over Trial in Healthy Older Adults
Norgren, Jakob; Daniilidou, Makrina; Kåreholt, Ingemar; Sindi, Shireen; Akenine, Ulrika; Nordin, Karin; Rosenborg, Staffan; Ngandu, Tiia; Kivipelto, Miia; Sandebring-Matton, Anna. 2021. Frontiers in aging neuroscience. 13: 716594 -
Sex and gender differences in genetic and lifestyle risk and protective factors for dementia
Sindi, Shireen; Toopchiani, Sima; Barbera, Mariagnese; Håkansson, Krister; Lehtisalo, Jenni; Rosenberg, Anna; Stephen, Ruth; Udeh-Momoh, Chinedu; Kivipelto, Miia. Teoksessa: Ferretti, Maria Teresa; Schumacher Dimech, Annemarie; Santuccione Chadha, Antonella(toim.) , 2021. Sex and Gender Differences in Alzheimer's Disease. s. 269-308. Academic press -
Sex differences in dementia and response to a lifestyle intervention: Evidence from Nordic population-based studies and a prevention trial
Sindi, S; Kåreholt, I; Ngandu, T; Rosenberg, A; Kulmala, J; Johansson, L; Wetterberg, H; Skoog, J; Sjöberg, L; Wang, HX; Fratiglioni, L; Skoog, I; Kivipelto, M. 2021. Alzheimer's & dementia. 17: 1166-1178 -
Telomere length change in a multidomain lifestyle intervention to prevent cognitive decline: a randomized clinical trial
Sindi, Shireen; Solomon, Alina; Kåreholt, Ingemar; Hovatta, Iiris; Antikainen, Riitta; Hänninen, Tuomo; Levälahti, Esko; Laatikainen, Tiina; Lehtisalo, Jenni; Lindström, Jaana; Paajanen, Teemu; Peltonen, Markku; Singh Khalsa, Dharma; Wolozin, Benjamin; Strandberg, Timo; Tuomilehto, Jaakko; Soininen, Hilkka; Ngandu, Tiia; Kivipelto, Miia; for the FINGER Study Group. 2021. Journals of gerontology series a: biological sciences and medical sciences. 76: 491-498 -
The effect of adherence on cognition in a multidomain lifestyle intervention (FINGER)
Ngandu, Tiia; Lehtisalo, Jenni; Korkki, Saana; Solomon, Alina; Coley, Nicola; Antikainen, Riitta; Bäckman, Lars; Hänninen, Tuomo; Lindström, Jaana; Laatikainen, Tiina; Paajanen, Teemu; Havulinna, Satu; Peltonen, Markku; Neely, Anna Stigsdotter; Strandberg, Timo; Tuomilehto, Jaakko; Soininen, Hilkka; Kivipelto, Miia. 2021. Alzheimer's & dementia. First published: 20 October 2021: 1 - 10 -
The effects of a physical and cognitive training intervention vs. physical training alone on older adults' physical activity: A randomized controlled trial with extended follow-up during COVID-19
Savikangas, Tiina; Törmäkangas, Timo; Tirkkonen, Anna; Alen, Markku; Fielding, Roger A.; Kivipelto, Miia; Rantalainen, Timo; Stigsdotter Neely, Anna; Sipilä, Sarianna. 2021. PLoS ONE. 16: 1 - 20 -
Association of Peripheral Insulin Resistance and Other Markers of Type 2 Diabetes Mellitus With Brain Amyloid Deposition in Healthy Individuals at Risk of Dementia
Pekkala, Timo; Hall, Anette; Mangialasche, Francesca; Kemppainen, Niina; Mecocci, Patrizia; Ngandu, Tiia; Rinne, Juha O; Soininen, Hilkka; Tuomilehto, Jaakko; Kivipelto. Miia; Solomon. Alina 1 2. 2020. Journal of Alzheimer's disease. 76: 1243-1248 -
Attitudes of at-risk older adults about prevention of cardiovascular disease and dementia using eHealth: a qualitative study in a European context.
Akenine, Ulrika; Barbera, Mariagnese; Beishuizen, Cathrien Rl; Fallah Pour, Mandana; Guillemont, Juliette; Rosenberg, Anna; Coley, Nicola; Mangialasche, Francesca; Salo, Lotta; Savy, Stephanie; Pols, A Jeannette; Andrieu, Sandrine; Richard, Edo; Soininen, Hilkka; Moll van Charante, Eric; Kivipelto, Miia; The HATICE study group. 2020. BMJ open. 10: e037050 -
Capillary blood tests may overestimate ketosis: triangulation between three different measures of ß-hydroxybutyrate
Norgren, J; Sindi, S; Sandebring-Matton, A; Kåreholt, I; Akenine, U; Nordin, K;, Rosenborg, S; Ngandu, T; Kivipelto, M. 2020. American journal of physiology : endocrinology and metabolism. 318: E184-E188 -
Cardiovascular health metrics from mid- to late-life and risk of dementia: A population-based cohort study in Finland
Liang, Yajun; Ngandu, Tiia; Laatikainen, Tiina; Soininen, Hilkka; Tuomilehto, Jaakko; Kivipelto, Miia; Qiu, Chengxuan. 2020. PLoS medicine. 17: e1003474 -
Combining Cognitive Markers to Identify Individuals at Increased Dementia Risk: Influence of Modifying Factors and Time to Diagnosis
Payton, Nicola; Rizzuto, Debora; Fratiglioni, Laura; Kivipelto, Miia; Bäckman, Lars; Laukka, Erika. 2020. Journal of the international neuropsychological society. 26: 785-797 -
Dementia risk scores as surrogate outcomes for lifestyle-based multidomain prevention trials - rationale, preliminary evidence and challenges
Coley, N; Hoevenaar-Blom, MP; van Dalen, JW; Moll van Charante, EP; Kivipelto, M; Soininen, H; Andrieu, S; Richard, E. 2020. Alzheimer's & dementia. 16: 1674-1685 -
Detecting Amyloid Positivity in Elderly With Increased Risk of Cognitive Decline
Pekkala, Timo; Hall, Anette; Ngandu, Tiia; Gils, Mark van; Helisalmi, Seppo; Hänninen, Tuomo; Kemppainen, Nina; Liu, Yawu; Lötjönen, Jyrki; Paajanen, Teemu; Rinne, Juha O; Soininen, Hilkka; Kivipelto, Miia; Solomon, Alina. 2020. Frontiers in aging neuroscience. 12: 228 -
Earlier life leisure-time physical activity in relation to age-related frailty syndrome
Kolehmainen, L; Havulinna, S; Ngandu, T; Strandberg, T; Levälahti, E; Lehtisalo, J; Antikainen, R; Hietikko, E; Peltonen, M; Pölönen, A; Soininen, H; Tuomilehto, J; Laatikainen, T; Rauramaa, R; Kivipelto, M; Kulmala, J. 2020. Age and ageing. 2021; 50: 161-168 -
Effects of daily L-dopa administration on learning and brain structure in older adults undergoing cognitive training: a randomised clinical trial
Lebedev, AV; Nilsson, J; Lindström, J; Fredborg, W; Akenine, U; Hillilä, C; Andersen, P; Spulber, G; de Lange, ECM; van den Berg, D-J; Kivipelto, M; Lövdén, M. 2020. Scientific reports. 10: 5227 -
Evaluation of a Novel Psychological Intervention Tailored for Patients With Early Cognitive Impairment (PIPCI): Study Protocol of a Randomized Controlled Trial
Ekman, Urban; Kemani, Mike K.; Wallert, John; Wicksell, Rikard K.; Holmström, Linda; Ngandu, Tiia; Rennie, Anna; Akenine, Ulrika; Westman, Eric; Kivipelto, Miia. 2020. Frontiers in psychology. 11: 600841 -
Experiences of dementia and attitude towards prevention: a qualitative study among older adults participating in a prevention trial
Rosenberg, Anna; Coley, Nicola; Soulier, Alexandra; Kulmala, Jenni; Soininen, Hilkka; Andrieu, Sandrine; Kivipelto, Miia; Barbera, Mariagnese; for the MIND-AD and HATICE groups. 2020. Bmc geriatrics. 20: 99 -
Ketosis After Intake of Coconut Oil and Caprylic Acid-With and Without Glucose: A Cross-Over Study in Healthy Older Adults
Norgren, Jakob; Sindi, Shireen; Sandebring-Matton, Anna; Kåreholt, Ingemar; Daniilidou, Makrina; Akenine, Ulrika; Nordin, Karin; Rosenborg, Staffan; Ngandu, Tiia; Kivipelto, Miia. 2020. Frontiers in nutrition. 7: 40 -
Late-life personality traits, cognitive impairment, and mortality in a population-based cohort
Neuvonen, Elisa; Hall, Anette; Tolppanen, Anna-Maija; Ngandu, Tiia; Rusanen, Minna; Laatikainen, Tiina; Soininen, Hilkka; Kivipelto, Miia; Solomon, Alina. 2020. International journal of geriatric psychiatry. 35: 989-999 -
Pooling individual participant data from randomized controlled trials: Exploring potential loss of information
van Wanrooij, Lennard L; Hoevenaar-Blom, Marieke P; Coley, Nicola; Ngandu, Tiia; Meiller, Yannick; Guillemont, Juliette; Rosenberg, Anna; Beishuizen, Cathrien R L; Moll van Charante, Eric P; Soininen, Hilkka; Brayne, Carol; Andrieu, Sandrine; Kivipelto, Miia; Richard, Edo. 2020. PLoS ONE. 15: e0232970 -
Precision prevention of Alzheimer's and other dementias: Anticipating future needs in the control of risk factors and implementation of disease-modifying therapies
Frisoni, GB; Molinuevo, JL; Altomare, D; Carrera, EM; Barkhof, F; Berkhof, J; Delrieu, J; Dubois, B; Kivipelto, M; Nordberg, A; Schott, JM; van der Flier, WM; Vellas, B; Jessen, F; Scheltens, P; Ritchie, C. 2020. Alzheimer's & dementia. 16: 1457-1468 -
Sleep disturbances and the speed of multimorbidity development in old age: results from a longitudinal population-based study
Sindi, Shireen; Pérez, Laura Monica; Vetrano, Davide L; Triolo, Federico; Kåreholt, Ingemar; Sjöberg, Linnea; Darin-Mattsson, Alexander; Kivipelto, Miia; Inzitari, Marco; Calderón-Larrañaga, Amaia. 2020. Bmc medicine. 18: 382 -
Tackling challenges in care of Alzheimer's disease and other dementias amid the COVID-19 pandemic, now and in the future
Mok, VCT; Pendlebury, S; Wong, A; Alladi, S; Au, L; Bath, PM; Biessels, GJ; Chen, C; Cordonnier, C; Dichgans, M; Dominguez, J; Gorelick, PB; Kim, S; Kwok, T; Greenberg, SM; Jia, J; Kalaria, R; Kivipelto, M; Naegandran, K; Lam, LCW; et al.. 2020. Alzheimer's & dementia. 16: 1571-1581 -
The potential long-term impact of the COVID-19 outbreak on patients with non-communicable diseases in Europe: consequences for healthy ageing
Palmer, Katie; Monaco, Alessandro; Kivipelto, Miia; Onder, Graziano; Maggi, Stefania; Michel, Jean-Pierre; Prieto, Rita; Sykara, Georgia; Donde, Shaantanu. 2020. Aging clinical and experimental research. 32: 1189-1194 -
Third follow-up of the Cardiovascular Risk Factors, Aging and Dementia (CAIDE) cohort investigating determinants of cognitive, physical, and psychosocial wellbeing among the oldest old: the CAIDE85+ study protocol
Barbera, Mariagnese; Kulmala, Jenni; Lisko, Inna; Pietilä, Eija; Rosenberg, Anna; Hallikainen, Ilona; Hallikainen, Merja; Laatikainen, Tiina; Lehtisalo, Jenni; Neuvonen, Elisa; Rusanen, Minna; Soininen, Hilkka; Tuomilehto, Jaakko; Ngandu, Tiia; Solomon, Alina; Kivipelto, Miia. 2020. Bmc geriatrics. 20: 238 -
White Matter Changes on Diffusion Tensor Imaging in the FINGER Randomized Controlled Trial
Stephen, Ruth; Solomon, Alina; Ngandu, Tiia; Levälahti, Esko; Rinne, Juha O; Kemppainen, Nina; Parkkola, Riitta; Antikainen, Riitta; Strandberg, Timo; Kivipelto, Miia; Soininen, Hilkka; Liu, Yawu. 2020. Journal of Alzheimer's disease. 78: 75-86 -
World-Wide FINGERS Network: A global approach to risk reduction and prevention of dementia
Kivipelto, M; Mangialasche, F; Snyder, HM; Allegri, R; Andrieu, S; Arai, H; Baker, L; Belleville, S; Brodaty, H; Brucki, SM; Calandri, I; Caramelli, P; Chen, C; Chertkow, H; Chew, E; Choi, SH; Chowdhary, N; Crivelli, L; De La Torre, R; Du, Y; et al. [Incl. Lehtisalo, J; Rosenberg, A; Soininen, H; Solomon, A]. 2020. Alzheimer's & dementia. 16: 1078-1094 -
cCOG: A web-based cognitive test tool for detecting neurodegenerative disorders
Rhodius-Meester, HFM; Paajanen, T; Koikkalainen, J; Mahdiani, S; Bruun, M; Baroni, M; Lemstra, AW; Scheltens, P; Herukka, SK; Pikkarainen, M; Hall, A; Hänninen, T; Ngandu, T; Kivipelto, M; van Gils, M; Hasselbalch, SG; Mecocci, P; Remes, A; Soininen, H; van der Flier, WM; Lötjönen, J. 2020. Alzheimer's & dementia : diagnosis, assessment & disease monitoring. 12: e12083 -
AMYPAD Diagnostic and Patient Management Study: Rationale and design
Frisoni, GB; Barkhof, F; Altomare, D; Berkhof, J; Boccardi, M; Canzoneri, E; Collij, L; Drzezga, A; Farrar, G; Garibotto, V; Gismondi, R; Gispert, JD; Jessen, F; Kivipelto, M; Alves, IL; Molinuevo, JL; Nordberg, A; Payoux, P; Ritchie, C; Savicheva, I; et al. (incl. Kivipelto, Miia). 2019. Alzheimer's & dementia. 15: 388-399 -
Adherence to multidomain interventions for dementia prevention: Data from the FINGER and MAPT trials
Coley, N; Ngandu, T; Lehtisalo, J; Soininen, H; Vellas, B; Richard, E; Kivipelto, M; Andrieu, S; HATICE, FINGER, MAPT/DSA groups. 2019. Alzheimer's & dementia. 15: 729-741 -
Alzheimer's Disease Composite Score: A Post-Hoc Analysis Using Data from the LipiDiDiet Trial in Prodromal Alzheimer's Disease
Hendrix, Suzanne B; Soininen, H; van Hees, AMJ; Ellison, N; Visser, PJ; Solomon, A; Attali, A; Blennow, K; Kivipelto, M; Hartmann, T. 2019. The Journal of prevention of Alzheimer's disease. 6: 232-236 -
Are the Neuroprotective Effects of Exercise Training Systemically Mediated?
Tari, AR; Norevik, CS; Scrimgeour, NR; Kobro-Flatmoen, A; Storm-Mathisen, J; Bergersen, LH; Wrann, CD; Selbæk, G; Kivipelto, M; Moreira, JBN; Wisløff, U. 2019. Progress in cardiovascular diseases. 62: 94-101 -
Association of Methionine to Homocysteine Status With Brain Magnetic Resonance Imaging Measures and Risk of Dementia
Hooshmand, B; Refsum, H; Smith, AD; Kalpouzos, G; Mangialasche, F; von Arnim, CAF; Kåreholt, I; Kivipelto, M; Fratiglioni, L. 2019. JAMA psychiatry. 76: 1198-1205 -
Brain volumes and cortical thickness on MRI in the Finnish Geriatric Intervention Study to Prevent Cognitive Impairment and Disability (FINGER)
Stephen, R; Liu, Y; Ngandu, T; Antikainen, R; Hulkkonen, J; Koikkalainen, J; Kemppainen, N; Lötjönen, J; Levälahti, E; Parkkola, R; Pippola, P; Rinne, J; Strandberg, T; Tuomilehto, J; Vanninen, R; Kivipelto, M; Soininen, H; Solomon, A. 2019. Alzheimer's research and therapy. 11: 53 -
Cardiorespiratory Fitness and Cognition: Longitudinal Associations in the FINGER Study
Pentikäinen, H; Savonen, K; Ngandu, T; Solomon, A; Komulainen, P; Paajanen, T; Antikainen, R; Kivipelto, M; Soininen, H; Rauramaa, R. 2019. Journal of Alzheimer's disease. 68: 961-968 -
Computer-based cognitive training for older adults: Determinants of adherence
Turunen, Merita; Hokkanen, Lauta; Bäckman, Lars; Stigsdotter-Neely, Anna; Hänninen, Tuomo; Paajanen, Teemu; Soininen, Hilkka; Kivipelto, Miia; Ngandu, Tiia. 2019. PLoS ONE. 14: e0219541 -
Dietary changes and cognition over 2 years within a multidomain intervention trial - The Finnish Geriatric Intervention Study to Prevent Cognitive Impairment and Disability (FINGER)
Lehtisalo, J; Levälahti, E; Lindström, J; Hänninen, T; Paajanen, T; Peltonen, M; Antikainen, R; Laatikainen, T; Strandberg, T; Soininen, H; Tuomilehto, J; Kivipelto, M; Ngandu, T. 2019. Alzheimer's & dementia. 15: 410-417 -
European Prevention of Alzheimer's Dementia Longitudinal Cohort Study (EPAD LCS): study protocol
Solomon, A; Kivipelto, M; Molinuevo, JL; Tom, B; Ritchie, CW. 2019. BMJ open. 8: e021017 -
From prediction to dementia prevention
Solomon, A; Ngandu, T; Kivipelto, M. Teoksessa: Irving, Kate; Hogervorst, Eef; Oliveira, Deborah; Kivipelto, Miia(toim.) , 2019. New Developments in Dementia Prevention Research : State of the Art and Future Possibilities. s. 13-26. Routledge -
Good for the heart and good for the brain?
Kivipelto, Miia; Ngandu, Tiia. 2019. The Lancet Neurology. 18: 327-328 -
Healthy ageing through internet counselling in the elderly (HATICE): a multinational, randomised controlled trial
Richard, Edo; van Charante, Eric P Moll; Hoevenaar-Blom, Marieke P; Coley, Nicola, Barbera, Mariagnese; van der Groep, Abraham; Meiller, Yannick; Mangialasche, Francesca; Beishuizen, Cathrien B; Jongstra, Susan; van Middelaar, Tessa; Van Wanrooij, Lennard L; Ngandu, Tiia; Guillemont, Juliette; Andrieu, Sandrine; Brayne, Carol; Kivipelto, Miia; Soininen, Hilkka; Van Gool, Willem A. 2019. The Lancet : digital health. 1: e424-e434 -
Integrating nurses' experiences with supporting behaviour change for cardiovascular prevention into a self-management internet platform in Finland and the Netherlands: a qualitative study
Beishuizen, CR; Akenine, U; Barbera, M; Rosenberg, A; Fallah Pour, M; Richard, E; Soininen, H; Mangialasche, F; Kivipelto, M; Pols, AJ; Moll van Charante, E. 2019. BMJ open. 9: e023480 -
Long-term dementia risk prediction by the LIBRA score: a 30-year follow-up of the CAIDE study
Deckers, K; Barbera, M; Köhler, S; Ngandu, T; van Boxtel, M; Rusanen, M; Laatikainen, T; Verhey, F; Soininen, H; Kivipelto, M; Solomon, A. 2019. International journal of geriatric psychiatry. 2020; 35: 195-203 -
Midlife improvements in financial situation are associated with a reduced dementia risk later in life: The CAIDE 30-Year Study
Sindi, S; Darin-Mattsson, A; Kåreholt, I; Kulmala, J; Ngandu, T; Laatikainen, T; Soininen, H; Kivipelto, M. 2019. International psychogeriatrics. [Published online 25 November 2019]: 1-8 -
Multidomain Interventions to Prevent Cognitive Impairment, Alzheimer's Disease, and Dementia: From FINGER to World-Wide FINGERS
Rosenberg, A; Mangialasche, F; Ngandu, T; Solomon, A; Kivipelto, M. 2019. The Journal of prevention of Alzheimer's disease. 2020; 7: 29-36 -
New Developments in Dementia Prevention Research : State of the Art and Future Possibilities
Irving, Kate; Hogervorst, Eef; Oliveira, Deborah; Kivipelto, Miia. 2019. Aging and Mental Health Research. . Routledge -
Older Adults' Reasons for Participating in an eHealth Prevention Trial: A Cross-Country, Mixed-Methods Comparison
Coley, N; Rosenberg, A; van Middelaar, T; Soulier, A; Barbera, M; Guillemont, J; Steensma, J; Igier, V; Eskelinen, M; Soininen, H; Moll van Charante, E; Richard, E; Kivipelto, M; Andrieu, S. 2019. Journal of the american medical directors association. 20: 843-849.e5 -
Predicting Development of Alzheimer's Disease in Patients with Shunted Idiopathic Normal Pressure Hydrocephalus
Luikku, AJ; Hall, A; Nerg, O; Koivisto, AM; Hiltunen, M; Helisalmi, S; Herukka, SK; Junkkari, A; Sutela, A; Kojoukhova, M; Korhonen, V; Mattila, J; Lötjönen, J; Rummukainen, J; Alafuzoff, I; Jääskeläinen, JE; Remes, AM; Solomon, A; Kivipelto, M; Soininen, H; et al. [Incl. Rauramaa, T; Leinonen, V]. 2019. Journal of Alzheimer's disease. 71: 1233-1243 -
Prediction models for dementia and neuropathology in the oldest old: the Vantaa 85+ cohort study
Hall, A; Pekkala, T; Polvikoski, T; van Gils, M; Kivipelto, M; Lötjönen, J; Mattila, J; Kero, M; Myllykangas, L; Mäkelä, M; Oinas, M; Paetau, A; Soininen, H; Tanskanen, M; Solomon, A. 2019. Alzheimer's research and therapy. 11: 11 -
Prevention of cognitive decline in old age - varying effects of interventions in different populations
Qiu, Chengxuan; Johansson, Gunilla; Zhu, Feiqi; Kivipelto, Miia; Winblad, Bengt. 2019. Annals of translational medicine. 7: S142 -
Progression to dementia in memory clinic patients with mild cognitive impairment and normal ß-amyloid
Rosenberg, A; Solomon, A; Jelic, V; Hagman, G; Bogdanovic, N; Kivipelto, M. 2019. Alzheimer's research and therapy. 11: 99 -
Self and Informant Memory Reports in FINGER: Associations with Two-Year Cognitive Change
Vaskivuo, L; Hokkanen, L; Hänninen, T; Antikainen, R; Bäckman, L; Laatikainen, T; Paajanen, T; Stigsdotter-Neely, A; Strandberg, T; Tuomilehto, J; Soininen, H; Kivipelto, M; Ngandu, T. 2019. Journal of Alzheimer's disease. 71: 785-795 -
Serum insulin and cognitive performance in older adults: a longitudinal study
Hooshmand, B; Rusanen, M; Ngandu, T; Leiviskä, J; Sindi, S; von Arnim, CAF; Falkai, P; Soininen, H; Tuomilehto, J; Kivipelto, M. 2019. American journal of medicine. 132: 367-373 -
The Effect of Multidomain Lifestyle Intervention on Daily Functioning in Older People
Kulmala, J; Ngandu, T; Havulinna, S; Levälahti, E; Lehtisalo, J; Solomon, A; Antikainen, R; Laatikainen, T; Pippola, P; Peltonen, M; Rauramaa, R; Soininen, H; Strandberg, T; Tuomilehto, J; Kivipelto, M. 2019. Journal of the american geriatrics society. 67: 1138-1144 -
The MOPEAD project: Advancing patient engagement for the detection of "hidden" undiagnosed cases of Alzheimer's disease in the community
Rodríguez-Gómez, O; Rodrigo, A; Iradier, F; Santos-Santos, MA; Hundemer, H; Ciudin, A; Sannemann, L; Zwan, M; Glaysher, B; Wimo, A; Bonn, J; Johansson, G; Rodriguez, I; Alegret, M; Gove, D; Pinó, S; Trigueros, P; Kivipelto, M; Mathews, B; Ciudad, A; et al.. 2019. Alzheimer's & dementia. 15: 828-839 -
Associations between Prospective and Retrospective Subjective Memory Complaints and Neuropsychological Performance in Older Adults: The Finger Study
Vaskivuo, Laura; Hokkanen, Laura; Hänninen, Tuomo; Antikainen, Riita; Bäckman, Lars; Laatikainen, Tiina; Paajanen, Teemu; Stigsdotter-Neely, Anna; Strandberg, Timo; Tuomilehto, Jaakko; Soininen, Hilkka; Kivipelto, Miia; Ngandu, Tiia. 2018. Journal of the international neuropsychological society. 24: 1099-1109 -
Brain ß-Amyloid and Atrophy in Individuals at Increased Risk of Cognitive Decline
Martikainen, IK; Kemppainen, N; Johansson, J; Teuho, J; Helin, S; Liu, Y; Helisalmi, S; Soininen, H; Parkkola, R; Ngandu, T; Kivipelto, M; Rinne, JO. 2018. American journal of neuroradiology. 2019; 40: 80-85 -
CAIDE dementia risk score, Alzheimer and cerebrovascular pathology: a population-based autopsy study
Hooshmand, B; Polvikoski, T; Kivipelto, M; Tanskanen, M; Myllykangas, L; Mäkelä, M; Oinas, M; Paetau, A; Solomon, A. 2018. Journal of internal medicine. 283: 597-603 -
Decreased plasma C-reactive protein levels in APOE E 4 allele carriers
Martiskainen, Henna; Takalo, Mari; Solomon, Alina; Stancáková, Alena; Marttinen, Mikael; Natunen, Teemu; Haapasalo, Annakaisa; Herukka, Sanna-Kaisa; Kuusisto, Johanna; Soininen, Hilkka; Kivipelto, Miia; Laakso, Markku; Hiltunen, Mikko. 2018. Annals of clinical and translational neurology. 5: 1229-1240 -
Designing an Internet-Based Multidomain Intervention for the Prevention of Cardiovascular Disease and Cognitive Impairment in Older Adults: The HATICE Trial
Barbera, Mariagnese; Mangialasche, Francesca; Jongstra, Susan; Guillemont, Juliette; Ngandu, Tiia; Beishuizen, Cathrien; Coley, Nicola; Brayne, Carol; Andrieu, Sandrine; Richard, Edo; Soininen, Hilkka; Kivipelto, Miia. 2018. Journal of Alzheimer's disease. 62: 649-663 -
Effect of the Apolipoprotein E Genotype on Cognitive Change During a Multidomain Lifestyle Intervention: A Subgroup Analysis of a Randomized Clinical Trial
Solomon, A; Turunen, H; Ngandu, T; Peltonen, M; Levälahti, E; Helisalmi, S; Antikainen, R; Bäckman, L; Hänninen, T; Jula, A; Laatikainen, T; Lehtisalo, J; Lindström, J; Paajanen, T; Pajala, S; Stigsdotter-Neely, A; Strandberg, T; Tuomilehto, J; Soininen, H; Kivipelto, M. 2018. JAMA neurology. 75: 462-470 -
European Prevention of Alzheimer's Dementia Registry: Recruitment and prescreening approach for a longitudinal cohort and prevention trials
Vermunt, L; Veal, CD; ter Meulen, L; Chrysostomou, C; van der Flier, W; Frisoni, GB; Guessous, I; Kivipelto, M; Marizzoni, M; Martinez-Lage, P; Molinuevo, JL; Porteous, D; Ritchie, K; Scheltens, P; Ousset, P-J; Ritchie, CW; Luscan, G; Brookes, AJ; Visser, PJ. 2018. Alzheimer's & dementia. 14: 837-842 -
Healthy Dietary Changes in Midlife Are Associated with Reduced Dementia Risk Later in Life
Sindi, Shireen; Kåreholt, Ingemar; Eskelinen, Marjo; Hooshmand, Babak; Lehtisalo, Jenni; Soininen, Hilkka; Ngandu, Tiia; Kivipelto, Miia. 2018. Nutrients. 10: 1649 -
Lifestyle interventions to prevent cognitive impairment, dementia and Alzheimer disease
Kivipelto, Miia; Mangialasche, Francesca; Ngandu, Tiia. 2018. Nature reviews neurology. 14: 653-666 -
Monimuotoiset elintapainterventiot muistisairausepidemian ehkäisyssä
Ngandu, Tiia; Kivipelto, Miia. 2018. Duodecim. 134: 2547-2553 -
Multidomain lifestyle intervention benefits a large elderly population at risk for cognitive decline and dementia regardless of baseline characteristics: The FINGER trial
Rosenberg, A; Ngandu, T; Rusanen, M; Antikainen, R; Bäckman, L; Havulinna, S; Hänninen, T; Laatikainen, T; Lehtisalo, J; Levälahti, E; Lindström, J; Paajanen, T; Peltonen, M; Soininen, H; Stigsdotter-Neely, A; Strandberg, T; Tuomilehto, J; Solomon, A; Kivipelto, M. 2018. Alzheimer's & dementia. 14: 263-270 -
Prevention Matters: Time for Global Action and Effective Implementation
Kulmala, Jenni; Ngandu, Tiia; Kivipelto, Miia. 2018. Journal of Alzheimer's disease. 64: S191-S198 -
Promoting safe walking among older people: the effects of a physical and cognitive training intervention vs. physical training alone on mobility and falls among older community-dwelling men and women (the PASSWORD study): design and methods of a randomized controlled trial
Sipilä, S; Tirkkonen, A; Hänninen, T; Laukkanen, P; Alen, M; Fielding, RA; Kivipelto, M; Kokko, K; Kulmala, J; Rantanen, T; Sihvonen, SE; Sillanpää, E; Stigsdotter-Neely, A; Törmäkangas, T. 2018. Bmc geriatrics. 18: 215 -
Sleep disturbances and dementia risk: A multicenter study
Sindi, S; Kåreholt, I; Johansson, L; Skoog, J; Sjöberg, L; Wang, HX; Johansson, B; Fratiglioni, L; Soininen, H; Solomon, A; Skoog, I; Kivipelto, M. 2018. Alzheimer's & dementia. 14: 1235-1242 -
Sleep disturbances and later cognitive status: a multi-centre study
Sindi, S; Johansson, L; Skoog, J; Mattsson, AD; Sjöberg, L; Wang, HX; Fratiglioni, L; Kulmala, J; Soininen, H; Solomon, A; Johansson, B; Skoog, I; Kivipelto, M; Kåreholt, I. 2018. Sleep medicine. 52: 26-33 -
The Effect of a 2-Year Intervention Consisting of Diet, Physical Exercise, Cognitive Training, and Monitoring of Vascular Risk on Chronic Morbidity - the FINGER Randomized Controlled Trial
Marengoni, A; Rizzuto, D; Fratiglioni, L; Antikainen, R; Laatikainen, T; Lehtisalo, J; Peltonen, M; Soininen, H; Strandberg, T; Tuomilehto, J; Kivipelto, M; Ngandu, T. 2018. Journal of the american medical directors association. 19: 355-360.e1 -
24-month intervention with a specific multinutrient in people with prodromal Alzheimer's disease (LipiDiDiet): a randomised, double-blind, controlled trial
Soininen Hilkka, Solomon Alina, Jelle Visser Pieter, Hendrix Suzanne B, Blennow Kaj, Kivipelto Miia, Hartmann Tobias, LipiDiDiet clinical study group. 2017. The Lancet Neurology. 16: 965-975 -
A Rare Success against Alzheimer's
Kivipelto M, Håkansson K. 2017. Scientific American. 316: 32-37 -
Associations of CAIDE Dementia Risk Score with MRI, PIB-PET measures, and cognition
Stephen R, Liu Y, Ngandu T, Rinne JO, Kemppainen N, Parkkola R, Laatikainen T, Paajanen T, Hänninen T, Strandberg T, Antikainen R, Tuomilehto J, Keinänen Kiukaanniemi S, Vanninen R, Helisalmi S, Levälahti E, Kivipelto M, Soininen H, Solomon A. 2017. Journal of Alzheimer's disease. 59: 695-705 -
Baseline Telomere Length and Effects of a Multidomain Lifestyle Intervention on Cognition: The FINGER Randomized Controlled Trial
Sindi Shireen, Ngandu Tiia, Hovatta Iiris, Kåreholt Ingemar, Antikainen Riitta, Hänninen Tuomo, Levälahti Esko, Laatikainen Tiina, Lindström Jaana, Paajanen Teemu, Peltonen Markku, Khalsa Dharma Singh, Wolozin Benjamin, Strandberg Timo, Tuomilehto Jaakko, Soininen Hilkka, Kivipelto Miia, Solomon Alina. 2017. Journal of Alzheimer's disease. 59: 1459-1470 -
Brain amyloid load and its associations with cognition and vascular risk factors in FINGER study
Kemppainen Nina, Johansson Jarkko, Teuho Jarmo, Parkkola Riitta, Joutsa Juho, Ngandu Tiika, Solomon Alina, Stephen Ruth, Liu Yawu, Hänninen Tuomo, Paajanen Teemu, Laatikainen Tiina, Soininen Hilkka, Jula Antti, Rokka Johanna, Rissanen Eero, Vahlberg Tero, Peltoniemi Julia, Kivipelto Miia, Rinne Juha O. 2017. Neurology. 2018; 90: e206-e213 -
Can lifestyle changes prevent cognitive impairment?
Kivipelto Miia, Mangialasche Francesca, Ngandu Tiia. 2017. The Lancet Neurology. 16: 338-339 -
Cardiorespiratory fitness and brain volumes in men and women in the FINGER study
Pentikäinen Heikki, Ngandu Tiia, Liu Yawu, Savonen Kai, Komulainen Pirjo, Hallikainen Merja, Kivipelto Miia, Rauramaa Rainer, Soininen Hilkka. 2017. Age and ageing. 46: 310-313 -
Health-related quality of life in a multidomain intervention trial to prevent cognitive decline (FINGER)
Strandberg TE, Levälahti E, Ngandu T, Solomon A, Kivipelto M, Lehtisalo J, Laatikainen T, Soininen H, Antikainen R, Jula A, Tuomilehto J, Peltonen M, Lindström J, Rauramaa R, Pajala S, Hänninen T, Solomon A, Paajanen T, Mangialasche F, FINGER Study Group. 2017. European geriatric medicine. 8: 164-167 -
Improving data sharing in research with context-free encoded missing data
Hoevenaar-Blom MP, Guillemont J, Ngandu T, Beishuizen CRL, Coley N, Moll van Charante EP, Andrieu S, Kivipelto M, Soininen H, Brayne C, Meiller Y, Richard E. 2017. PLoS ONE. 12: e0182362 -
Midlife Work-Related Stress is Associated with Late-Life Gray Matter Volume Atrophy
Sindi, Shireen; Kåreholt, Ingemar; Spulber, Gabriela; Soininen, Hilkka; Kivipelto, Miia; Solomon, Alina. 2017. Journal of Alzheimer's disease reports. 1: 219-227 -
Midlife work-related stress is associated with late-life cognition
Sindi S, Kåreholt I, Solomon A, Hooshmand B, Soininen H, Kivipelto M. 2017. Journal of neurology. 264: 1996-2002 -
Muistisairauksien riskitekijät ja ennaltaehkäisy
Kivipelto Miia, Ngandu Tiia. Teoksessa: Jousimaa Jukkapekka, Alenius Heidi, Atula Sari, Berghem Nora, Kattainen Anna, Kunnamo Ilkka, Pelttari Hanna, Teikari Martti(toim.) , 2017. Lääkärin käsikirja, 12. uudistettu painos. s. 1450-1452. Duodecim -
Muscle strength and cognition in ageing men and women: The DR's EXTRA study
Pentikäinen H, Savonen K, Komulainen P, Kiviniemi V, Paajanen T, Kivipelto M, Soininen H, Rauramaa R. 2017. European geriatric medicine. 8: 275-277 -
Nutrient intake and dietary changes during a 2-year multi-domain lifestyle intervention among older adults: secondary analysis of the Finnish Geriatric Intervention Study to Prevent Cognitive Impairment and Disability (FINGER) randomised controlled trial
Lehtisalo Jenni, Ngandu Tiia, Valve Päivi, Antikainen Riitta, Laatikainen Tiina, Strandberg Timo, Soininen Hilkka, Tuomilehto Jaakko, Kivipelto Miia, Lindström Jaana. 2017. British journal of nutrition. 118: 291-302 -
Postmenopausal hormone therapy and Alzheimer disease. A prospective cohort study
Imtiaz B, Tuppurainen M, Rikkonen T, Kivipelto M, Soininen H, Kröger H, Tolppanen A-M. 2017. Neurology. 88: 1062-1068 -
Risk of Alzheimer's disease among users of postmenopausal hormonetherapy: A nationwide case-control study
Imtiaz B, Taipale H, Tanskanen A, Tiihonen M, Kivipelto M, Heikkinen A-M, Tiihonen J, Soininen H, Hartikainen S, Tolppanen A-M. 2017. Maturitas. 98: 7-13 -
Self-rated physical fitness and estimated maximal oxygen uptake in relation to all-cause and cause-specific mortality
Solomon A, Borodulin, Ngandu T, Kivipelto M, Laatikainen T, Kulmala J. 2017. Scandinavian journal of medicine and science in sports. 2018; 28: 532-540 -
Terveet elämäntavat - terveet aivot
Strandberg Timo, Kivipelto Miia. 2017. Duodecim. 133: 195-200 -
World Wide Fingers will advance dementia prevention
Kivipelto Miia, Mangialasche Francesca, Ngandu Tiia, World Wide Fingers Network. 2017. The Lancet Neurology. 17: 27 -
Association of Vitamin B12, Folate, and Sulfur Amino Acids With Brain Magnetic Resonance Imaging Measures in Older Adults: A Longitudinal Population-Based Study
Hooshmand B, Mangialasche F, Kalpouzos G, Solomon A, Kåreholt I, Smith AD, Refsum H, Wang R, Mühlmann M, Ertl-Wagner B, Laukka EJ, Bäckman L, Fratiglioni L, Kivipelto M. 2016. JAMA psychiatry. 73: 606-613 -
Association of long-term dietary fat intake, exercise, and weight with later cognitive function in the Finnish Diabetes Prevention Study
Lehtisalo J, Lindström J, Ngandu T, Kivipelto M, Ahtiluoto S, Ilanne-Parikka P, Keinänen-Kiukaanniemi S, Eriksson JG, Uusitupa M, Tuomilehto J, Luchsinger J. 2016. Journal of nutrition health and aging. 20: 146-154 -
CAIDE Dementia Risk Score and biomarkers of neurodegeneration in memory clinic patients without dementia.
Enache D, Solomon A, Cavallin L, Kåreholt I, Kramberger MG, Aarsland D, Kivipelto M, Eriksdotter M, Winblad B, Jelic V. 2016. Neurobiology of aging. 42: 124-131 -
Defeating Alzheimer's disease and other dementias: a priority for European science and society
Winblad B, Amouyel P, Andrieu S, Ballard C, Brayne C, Brodaty H, Cedazo-Minguez A, Dubois B, Edvardsson D, Feldman H, Fratiglioni L, Frisoni GB, Gauthier S, Georges J, Graff C, Iqbal K, Jessen F, Johansson G, Jönsson L, Kivipelto M et al. 2016. The Lancet Neurology. 15: 455-532 -
Development and Validation of an Interactive Internet Platform for Older People: The Healthy Ageing Through Internet Counselling in the Elderly Study
Jongstra Susan, Beishuizen Cathrien, Andrieu Sandrine, Barbera Mariagnese, van Dorp Matthijs, van de Groep Bram, Guillemont Juliette, Mangialasche Francesca, van Middelaar Tessa, Moll van Charante Eric, Soininen Hilkka, Kivipelto Miia, Richard Edo. 2016. Telemedicine and e-health. 2017; 23: 1-9 -
Development of a Late-Life Dementia Prediction Index with Supervised Machine Learning in the Population-Based CAIDE Study
Pekkala Timo, Hall Anette, Lötjönen Jyrki, Mattila Jussi, Soininen Hilkka, Ngandu Tiia, Laatikainen Tiina, Kivipelto Miia, Solomon Alina. 2016. Journal of Alzheimer's disease. 2017; 55: 1055-1067 -
Estimates of global, regional, and national incidence, prevalence, and mortality of HIV, 1980-2015: the Global Burden of Disease Study 2015
GBD 2015 HIV Collaborators (including Kivipelto Miia). 2016. The Lancet HIV. 3: e361-e387 -
Estradiol and Cognition in the Cardiovascular Risk Factors, Aging and Dementia (CAIDE) Cohort Study
Imtiaz Bushra, Tolppanen Anna-Maija, Solomon Alina, Soininen Hilkka, Kivipelto Miia. 2016. Journal of Alzheimer's disease. 2017; 56: 453-458 -
From Heart Health to Brain Health: Legacy of the North Karelia Project for Dementia Research
Kivipelto Miia, Ngandu Tiia. 2016. Global heart. 11: 235-242 -
Healthy ageing through internet counselling in the elderly: the HATICE randomised controlled trial for the prevention of cardiovascular disease and cognitive impairment
Richard Edo, Jongstra Susan, Soininen Hilkka, Brayne Carol, Moll van Charante Eric P, Meiller Yannick, van der Groep Bram, Beishuizen Cathrien RL, Mangialasche Francesca, Barbera Mariagnese, Ngandu Tiia, Coley Nicola, Guillemont Juliette, Savy Stéphanie, Dijkgraaf Marcel GW, Peters Ron JG, van Gool Willem A, Kivipelto Miia, Andrieu Sandrine. 2016. BMJ open. 6: e010806 -
Leisure-Time and Occupational Physical Activity in Early and Late Adulthood in Relation to Later Life Physical Functioning
Kulmala Jenni, Ngandu Tiia, Pajala Satu, Lehtisalo Jenni, Levälahti Esko, Antikainen Riitta, Laatikainen Tiina, Oksa Heikki, Peltonen Markku, Raurama Rainer, Soininen Hilkka, Strandberg Timo, Tuomilehto Jaakko, Kivipelto Miia. 2016. Journal of physical activity and health. 13: 1079-1087 -
Midlife work-related stress increases dementia risk in later life: the CAIDE 30-year study
Sindi Shireen, Hagman Göran, Håkansson Krister, Kulmala Jenni, Nilsen Charlotta, Kåreholt Ingemar, Soininen Hilkka, Solomon Alina, Kivipelto Miia. 2016. Journals of gerontology series b: psychological sciences and social sciences. 2017; 72: 1044-1053 -
Preclinical Alzheimer's disease: Definition, natural history, and diagnostic criteria
Dubois Bruno, Hampel Harald, Feldman Howard H, Scheltens Philip, Aisen Paul, Andrieu Sandrine, Bakardjian Hovagim, Benali Habib, Bertram Lars, Blennow Kaj, Broich Karl, Cavedo Enrica, Crutch Sebastian, Dartigues Jean-Francois, Duyckaerts Charles, Epelbaum Stéphane, Frisoni Giovanni B, Gauthier Serge, Genthon Remy, Gouw Alida A et al. 2016. Alzheimer's & dementia. 12: 292-323 -
Web-Based Interventions Targeting Cardiovascular Risk Factors in Middle-Aged and Older People: A Systematic Review and Meta-Analysis
Beishuizen Cathrien RL, Stephan Blossom CM, van Gool Willem A, Brayne Carol, Peters Ron JG, Andrieu Sandrine, Kivipelto Miia, Soininen Hilkka, Busschers Wim B, Moll van Charante Eric P, Richard Edo. 2016. Journal of medical internet research. 18: e55 -
A 2 year multidomain intervention of diet, exercise, cognitive training, and vascular risk monitoring versus control to prevent cognitive decline in at-risk elderly people (FINGER): a randomised controlled trial
Ngandu Tiia, Lehtisalo Jenni, Solomon Alina, Levälahti Esko, Ahtiluoto Satu, Antikainen Riitta, Bäckman Lars, Hänninen Tuomo, Jula Antti, Laatikainen Tiina, Lindström Jaana, Mangialasche Francesca, Paajanen Teemu, Pajala Satu, Peltonen Markku, Rauramaa Rainer, Stigsdotter-Neely Anna, Strandberg T, Tuomilehto J, Soininen Hilkka, Kivipelto Miia. 2015. The Lancet. 385: 2255-2263 -
Advances in the prevention of Alzheimer's Disease
Sindi Shireen, Mangialasche Francesca, Kivipelto Miia. 2015. F1000 prime. published 12 May 2015: 12 p -
Advances in the therapy of Alzheimer's disease : targeting amyloid beta and tau and perspectives for the future
Hampel Harald, Schneider Lon S, Giacobini Ezio, Kivipelto Miia, Sindi Shireen, Dubois Bruno, Broich Karl, Nisticò Robert, Aisen Paul S, Lista Simone. 2015. Expert review of neurotherapeutics. 15: 83-105 -
Cognition in the Finnish Diabetes Prevention Study
Luchsinger José A, Lehtisalo Jenni, Lindström Jaana, Ngandu Tiia, Kivipelto Miia, Ahtiluoto Satu, Ilanne-Parikka Pirjo, Keinänen-Kiukaanniemi Sirkka, Eriksson Johan G, Uusitupa Matti, Tuomilehto Jaakko, for the Finnish Diabetes Prevention Study (DPS). 2015. Diabetes research and clinical practice. 108: e63-e66 -
Diabetes, glycaemia, and cognition - a secondary analysis of the Finnish Diabetes Prevention Study
Lehtisalo Jenni, Lindström Jaana, Ngandu Tiia, Kivipelto Miia, Ahtiluoto Satu, Ilanne-Parikka Pirjo, Keinänen-Kiukaanniemi Sirkka, Eriksson Johan G., Uusitupa Matti, Tuomilehto Jaakko, Luchsinger Jose A, for the Finnish Diabetes Prevention Study (DPS). 2015. Diabetes/metabolism research and reviews. [epub ahead of print 18 AUG 2015]: - -
Feelings of Hopelessness in Midlife and Cognitive Health in Later Life: A Prospective Population-Based Cohort Study
Håkansson Krister, Soininen Hilkka, Winblad Bengt, Kivipelto Miia. 2015. PLoS ONE. 10: e0140261 -
Global, regional, and national age-sex specific all-cause and cause-specific mortality for 240 causes of death, 1990-2013 : a systematic analysis for the Global Burden of Disease Study 2013
GBD 2013 Mortality and Causes of Death Collaborators incl. Miia Kivipelto. 2015. The Lancet. 385: 117-171 -
Global, regional, and national comparative risk assessment of 79 behavioural, environmental and occupational, and metabolic risks or clusters of risks in 188 countries, 1990-2013: a systematic analysis for the Global Burden of Disease Study 2013
Forouzanfar Mohammad H, Alexander Lily, Anderson H Ross, Bachman Victoria F, Biryukov Stan, Brauer Michael, Burnett Richard, Casey Daniel, Coates Matthew M, Cohen Aaron, Delwiche Kristen, Estep Kara, Frostad Joseph J, Kc Astha, Kyu Hmwe H, Moradi-Lakeh Maziar, Ng Marie, Slepak Erica Leigh, Thomas Bernadette A, Wagner Joseph et al. GBD 2013 Risk Factors Collaborators (incl. Kivipelto Miia). 2015. The Lancet. 386: 2287-2323 -
Global, regional, and national disability-adjusted life years (DALYs) for 306 diseases and injuries and healthy life expectancy (HALE) for 188 countries, 1990-2013: quantifying the epidemiological transition
Murray Christopher JL, Barber Ryan M, Foreman Kyle J, Ozgoren Ayse Abbasoglu, Abd-Allah Foad, Abera Semaw F, Aboyans Victor, Abraham Jerry P, Abubakar Ibrahim, Abu-Raddad Laith J, Abu-Rmeileh Niveen M, Achoki Tom, Ackerman Ilena N, Ademi Zanfina, Adou Arsène K, Adsuar José C, Afshin Ashkan, Agardh Emilie E, Alam Sayed Saidul, Alasfoor Deena et al., GBD 2013 DALYs and HALE Collaborators (incl. Kivipelto Miia). 2015. The Lancet. 386: 2145-2191 -
Global, regional, and national incidence, prevalence, and years lived with disability for 301 acute and chronic diseases and injuries in 188 countries, 1990-2013: a systematic analysis for the Global Burden of Disease Study 2013
Vos Theo, Barber Ryan M, Bell Brad, Bertozzi-Villa Amelia, Biryukov Stan, Bolliger Ian, Charlson Fiona, Davis Adrian, Degenhardt Louisa, Dicker Daniel, Duan Leilei, Erskine Holly, Feigin Valery L, Ferrari Alize J, Fitzmaurice Christina, Fleming Thomas, Graetz Nicholas, Guinovart Caterina, Haagsma Juanita, Hansen Gillian M et al, Global Burden of Disease Study 2013 Collaborators (incl. Kivipelto M). 2015. The Lancet. 386: 743-800 -
Lymphocytic Mitochondrial Aconitase Activity is Reduced in Alzheimer's Disease and Mild Cognitive Impairment
Mangialasche Francesca, Baglioni Mauro, Cecchetti Roberta, Kivipelto Miia, Ruggiero Carmelinda, Piobbico Danilo, Kussmaul Lothar, Monastero Roberto, Brancorsini Stefano, Mecocci Patrizia. 2015. Journal of Alzheimer's disease. 44: 649-660 -
Midlife CAIDE Dementia Risk Score and Dementia-Related Brain Changes up to 30 Years Later on Magnetic Resonance Imaging
Vuorinen Miika, Spulber Gabriela, Soheil Damingir, Niskanen Eini, Ngandu Tiia, Soininen Hilkka, Kivipelto Miia, Soloman Alina. 2015. Journal of Alzheimer's disease. 44: 93-101 -
Muistisairauksien ennaltaehkäisy
Soininen Hilkka, Kivipelto Miia. Teoksessa: Timo Erkinjuntti, Anne Remes, Juha Rinne, Hilkka Soininen(toim.) , 2015. Muistisairaudet. s. 436-445. Kustannus Oy Duodecim -
New Strategy to Reduce the Global Burden of Stroke
Feigin Valery L, Krishnamurthi Rita, Bhattacharjee Rohit, Parmar Priya, Theadom Alice, Hussein Tasleem, Purohit Mitali, Hume Patria, Abbott Max, Rush Elaine, Kasabov Nikola, Crezee Ineke, Frielick Stanley, Barker-Collo Suzanne, Barber P Alan, Arroll Bruce, Poulton Richie, Ratnasabathy Yogini, Tobias Martin, Cabral Norberto et al (inc. Miia Kivipelto). 2015. Stroke. 46: 1740-1747 -
Pointing the FINGER at multimodal dementia prevention - Authors' reply
Kivipelto Miia, Mangialasched Francesca, Solomon Alina on behalf of the FINGER Study Group. 2015. The Lancet. 386: 1627 -
Target risk factors for dementia prevention : a systematic review and Delphi consensus study on the evidence from observational studies
Deckers Kay, van Boxtel Martin PJ, Schiepers Olga JG, de Vugt Marjolein, Muñoz Sánchez Juan Luis, Anstey Kaarin J, Brayne Carol, Dartigues Jean-Francois, Engedal Knut, Kivipelto Miia, Ritchie Karen, Starr John M, Yaffe Kristine, Irving Kate, Verhey Frans RJ, Köhler Sebastian. 2015. International journal of geriatric psychiatry. 30: 234-246 -
The CAIDE Dementia Risk Score App: The development of an evidence-based mobile application to predict the risk of dementia
Sindi Shireen, Calov Elisabeth, Fokkens Jasmine, Ngandu Tiia, Soininen Hilkka, Tuomilehto Jaakko, Kivipelto Miia. 2015. Alzheimer's & dementia : diagnosis, assessment & disease monitoring. 1: 328-333 -
The Nordic diet and cognition - The DR's EXTRA Study
Männikkö Reija, Komulainen Pirjo, Schwab Ursula, Heikkilä Harri M, Savonen Kai, Hassinen Maija, Hänninen Tuomo, Kivipelto Miia, Rauramaa Rainer. 2015. British journal of nutrition. 114: 231-239 -
The Stroke RiskometerTM App : Validation of a data collection tool and stroke risk predictor
Parmar Priya, Krishnamurthi Rita, Ikram M. Arfa, Hofman Albert, Mirza Saira S, Varakin Yury, Kravchenko Michael, Piradov Michael, Thrift Amanda G, Norrving Bo, Wang Wenzhi, Mandal Dipes Kumar, Barker-Collo Suzanne, Sahathevan Ramesh, Davis Stephen, Saposnik Gustavo, Kivipelto Miia, Sindi Shireen, Bornstein Natan M, Giroud Maurice et al. 2015. International journal of stroke. 10: 231-244 -
Why has therapy development for dementia failed in the last two decades?
Gauthier S, Albert M, Fox N, Goedert M, Kivipelto M, Mestre-Ferrandiz J, Middleton LT. 2015. Alzheimer's & dementia. 2016; 12: 60-64 -
9th Key symposium introduction: Updating Alzheimer's disease diagnosis implications for prevention and treatment
Kivipelto M, Mangialasche F, Solomon A, Johansson G, Lannfelt L, Fratiglioni L, Winblad B. 2014. Journal of internal medicine. 275: 202-203 -
Advances in the prevention of Alzheimer's disease and dementia
Solomon A, Mangialasche F, Richard E, Andrieu S, Bennett DA, Breteler B, Fratiglioni L, Hooshmand B, Khachaturian AS, Schneider LS, Skoog I, Kivipelto M. 2014. Journal of internal medicine. 275: 229-250 -
Association between mid- to late life physical fitness and dementia: evidence from the CAIDE study
Kulmala J, Solomon A, Kåreholt I, Ngandu T, Rantanen T, Laatikainen T, Soininen H, Tuomilehto J, Kivipelto M. 2014. Journal of internal medicine. 276: 296-307 -
Clinical trials and late-stage drug development for Alzheimer's disease: an appraisal from 1984 to 2014
Schneider LS, Mangialasche F, Andreasen N, Feldman H, Giacobini E, Jones R, Mantua V, Mecocci P, Pani L, Winblad B, Kivipelto M. 2014. Journal of internal medicine. 275: 251-283 -
Coronary Heart Disease and Cortical Thickness, Gray Matter and White Matter Lesion Volumes on MRI
Vuorinen Miika, Damangir Soheil, Niskanen Eini, Miralbell Julia, Rusanen Minna, Spulber Gabriela, Soininen Hilkka, Kivipelto Miia, Solomon Alina. 2014. PLoS ONE. 9: e109250, 1-9 -
Future directions in Alzheimer's disease from risk factors to prevention
Imtiaz Bushra, Tolppanen Anna-Maija, Kivipelto Miia, Soininen Hilkka. 2014. Biochemical pharmacology. 88: 661-670 -
Heart diseases and long-term risk of dementia and Alzheimer's disease: a population-based CAIDE study
Rusanen Minna, Kivipelto Miia, Levälahti Esko, Laatikainen Tiina, Tuomilehto Jaakko, Soininen Hilkka, Ngandu Tiia. 2014. Journal of Alzheimer's disease. 42: 183-191 -
Late-life cynical distrust, risk of incident dementia, and mortality in a population-based cohort
Neuvonen Elisa, Rusanen Minna, Solomon Alina, Ngandu Tiia, Laatikainen Tiina, Soininen Hilkka, Kivipelto Miia, Tolppanen Anna-Maija. 2014. Neurology. 82: 2205-2212 -
Leisure-time physical activity from mid- to late life, body mass index, and risk of dementia
Tolppanen Anna-Maija, Solomon Alina, Kulmala Jenni, Kåreholt Ingemar, Ngandu Tiia, Rusanen Minna, Laatikainen Tiina, Soininen Hilkka, Kivipelto Miia. 2014. Alzheimer's & dementia. Epub ahead of print: - -
Modifiable lifestyle factors in dementia: A systematic review of longitudinal observational cohort studies
Di Marco Luigi Yuri, Marzo Alberto, Munoz-Ruiz Miguel, Arfan Ikram M, Kivipelto Miia, Ruefenacht Daniel, Venneri Annalena, Soininen Hilkka, Wanke Isabel, Ventikos Yiannis A, Frangi Alejandro F. 2014. Journal of Alzheimer's disease. 42: 119-135 -
Oophorectomy, Hysterectomy, and Risk of Alzheimer's Disease: A Nationwide Case-Control Study
Imtiaz Bushra, Tuppurainen Marjo, Tiihonen Miia, Kivipelto Miia, Soininen Hilkka, Hartikainen Sirpa, Tolppanen Anna-Maija. 2014. Journal of Alzheimer's disease. 42: 575-581 -
Vitamin D in relation to cognitive impairment, cerebrospinal fluid biomarkers, and brain volumes
Hooshmand Babak, Lökk Johan, Solomon Alina, Mangialasche Francesca, Miralbell Julia, Spulber Gabriela, Annerbo Sylvia, Andreasen Niels, Winblad Bengt, Cedazo-Minguez Angel, Wahlund Lars-Olof, Kivipelto Miia. 2014. Journals of gerontology series a: biological sciences and medical sciences. -: 7 s. -
Changes in vascular factors 28 years from midlife and late-life cortical thickness
Vuorinen M, Kåreholt I, Julkunen V, Spulber G, Niskanen E, Paajanen T, Soininen H, Kivipelto M, Solomon A. 2013. Neurobiology of aging. 34: 100-109 -
Cholesterol, statins, and late-life cognitive disorders.
Solomon A, Kivipelto M. Teoksessa: Yaffe Kristine(toim.) , 2013. Chronic Medical Disease and Cognitive Aging. Toward a healthy body and brain. s. 13-39. Oxford University Press -
Chronic obstructive pulmonary disease and asthma and the risk of mild cognitive impairment and dementia: a population based CAIDE study
Rusanen M, Ngandu T, Laatikainen T, Tuomilehto J, Soininen H, Kivipelto M. 2013. Current alzheimer research. 10: 549-555 -
Classification and prediction of clinical diagnosis of Alzheimer's disease based on MRI and plasma measures of alpha-/gamma-tocotrienols and gamma-tocopherol
Mangialasche F, Westman E, Kivipelto M, Muehlboeck J-S, Cecchetti R, Baglioni M, Tarducci R, Gobbi G, Floridi P, Soininen H, Kloszewska I, Tsolaki M, Vellas B, Spenger C, Lovestone S, Wahlund L-O, Simmons A, Mecocci P. 2013. Journal of internal medicine. 273: 602-621 -
Diagnostic power of 24S-hydroxycholesterol in cerebrospinal fluid: Candidate marker of brain health
Leoni V, Solomon A, Lövgren-Sandholm A, Blennow K, Hansson O, Wahlund L-O, Kivipelto M, Björkhem I. 2013. Journal of Alzheimer's disease. 36: 739-747 -
GRN variant rs5848 reduces plasma and brain levels of granulin in Alzheimer's disease patients
Kämäläinen A, Viswanathan J, Natunen T, Helisalmi S, Kauppinen T, Pikkarainen M, Pursiheimo J-P, Alafuzoff I, Kivipelto M, Haapasalo A, Soininen H, Herukka S-K, Hiltunen M. 2013. Journal of Alzheimer's disease. 33: 23-27 -
History of medically treated diabetes and risk of Alzheimer disease in a nationwide case-control study
Tolppanen Anna-Maija, Lavikainen Piia, Solomon Alina, Kivipelto Miia, Uusitupa Matti, Soininen Hilkka, Hartikainen Sirpa. 2013. Diabetes care. 36: 2015-2019 -
Incidence of stroke in people with Alzheimer disease. A national register-based approach
Tolppanen Anna-Maija, Lavikainen Piia, Solomon Alina, Kivipelto Miia, Soininen Hilkka, Hartikainen Sirpa. 2013. Neurology. 80: 353-358 -
Midlife and late-life body mass index and late-life dementia: results from a prospective population-based cohort
Tolppanen A-M, Ngandu T, Kåreholt I, Laatikainen T, Rusanen M, Soininen H, Kivipelto M. 2013. Journal of Alzheimer's disease. online: - -
Muistisairauksien ehkäisy ja riskitekijät
Kivipelto M, Ngandu T. Teoksessa: Hallikainen M, Mönkäre R, Nukari T, Folder M(toim.) , 2013. Muistisairaan kuntouttava hoito. s. 26-29. Kustannus Oy Duodecim -
Plasma homocysteine, Alzheimer and cerebrovascular pathology: a population-based autopsy study
Hooshmand B, Polvikoski T, Kivipelto M, Tanskanen M, Myllykangas L, Erkinjuntti T, Mäkelä M, Oinas M, Paetau A, Scheltens P, van Straaten ECW, Sulkava R, Solomon A. 2013. Brain. 136: 2707-2716 -
Prevention of Alzheimer's Disease: Moving backward through the lifespan
Solomon A, Kivipelto M, Soininen H. 2013. Journal of Alzheimer's disease. 33: S465-S469 -
Risk factors for incident dementia in the very old
Wallin K, Boström G, Kivipelto M, Gustafson Y. 2013. International psychogeriatrics. 25: 1135-43 -
Serum levels of vitamin E forms and risk of cognitive impairment in a Finnish cohort of older adults
Mangialasche F, Solomon A, Kåreholt I, Hooshmand B, Cecchetti R, Fratiglioni L, Soininen H, Laatikainen T, Mecocci P, Kivipelto M. 2013. Experimental gerontology. 48: 1428-1435 -
The Finnish Geriatric intervention study to prevent cognitive impairment and disability (FINGER): Study design and progress
Kivipelto M, Solomon A, Ahtiluoto S, Ngandu T, Lehtisalo J, Antikainen R, Bäckman L, Hänninen T, Jula A, Laatikainen T, Lindström J, Mangialasche F, Nissinen A, Paajanen T, Pajala S, Peltonen M, Rauramaa R, Stigsdotter-Neely A, Strandberg T, Tuomilehto J, Soininen H. 2013. Alzheimer's & dementia. 9: 657-665 -
Validity of dementia and Alzheimer disease diagnoses in Finnish national registers
Solomon A, Ngandu T, Soininen H, Hallikainen M, Kivipelto M, Laatikainen T. 2013. Alzheimer's & dementia. Epub: 1-7 -
Associations between serum homocysteine, holotranscobalamin, folate and cognition in the elderly: a longitudinal study
Hooshmand B, Solomon A, Kåreholt I, Rusanen M, Hänninen T, Leivistä J, Winblad B, Laatikainen T, Soininen H, Kivipelto M. 2012. Journal of internal medicine. 271: 204-212 -
Cortical thickness in frontotemporal dementia, mild cognitive impairment, and Alzheimer's Disease
Hartikainen P, Räsänen J, Julkunen V, Niskanen E, Hallikainen M, Kivipelto M, Vanninen R, Remes AM, Soininen H. 2012. Journal of Alzheimer's disease. 30: 857-874 -
Dementia after age 75: Survival in different severity stages and years of life lost
Rizzuto D, Bellocco R, Kivipelto M, Clerici F, Wimo A, Fragtiglioni L. 2012. Current alzheimer research. 9: 795-800 -
Dementia prevention: current epidemiological evidence and future perspective
Mangialasche F, Kivipelto M, Solomon M, Fratiglioni L. 2012. Alzheimer's research and therapy. 4: 1-8 -
Differences in brain cholestero metabolism and insulin in two subgroups of patients with different CSF biomarkers but similar white matter lesions suggest different pathogenic mechanisms
Besga A, Cedazo-Minguez A, Kåreholt I, Solomon A, Björkhem I, Winblad B, Leoni V, Hooshmand B, Spulber G, Gonzales-Pinto A, Kivipelto M, Wahlund LO. 2012. Neuroscience letters. 510: 121-126 -
Education halves the risk of dementia due to apolipoprotein epsilon4 allele: a collaborative study from the Swedish Brain Power initiative
Wang H-X, Gustafson DR, Kivipelto M, Pedersen NL, Skoog I, Windblad B, Fratiglioni L. 2012. Neurobiology of aging. 33: 1007.e1-1007.e7 -
Evolution of global and local grey matter atrophy on serial MRI scans during the progression from MCI to AD
Spulber G, Niskanen E, MacDonald S, Kivipelto M, Ferreira Padilla D, Julkunen V, Hallikainen M, Vanninen R, Wahlund L-O, Soininen H. 2012. Current alzheimer research. 9: 516-524 -
Grey matter and cognitive patterns in cognitive impaired subjects using CSF biomarker cut-offs
Miralbell J, Spulber G, Hooshmand B, Besga A, Mataro M, Cedazo-Minguez A, Kivipelto M, Wahlund L-O. 2012. Journal of Alzheimer's disease. 29: 741-749 -
Methodological challenges in designing dementia prevention trials - The European Dementia Prevention Initiative (EDPI)
Richard E, Andrieu S, Solomon A, Mangialasche F, Ahtiluoto S, Moll van Charante EP, Coley N, Fratiglioni L, Stigsdotter Neely A, Vellas B, van Gool WA, Kivipelto M. 2012. Journal of the neurological sciences. 322: 64-70 -
Midlife Vascular Risk Factors and Alzheimer's Disease: Evidence from Epidemiological Studies
Tolppanen AM, Solomon A, Soininen H, Kivipelto M. 2012. Journal of Alzheimer's disease. 32: 531-40 -
Midlife rheumatoid arthritis increases the risk of cognitive impairment two decades later: A population-based study
Wallin K, Solomon A, Kåreholt I, Tuomilehto J, Soininen H, Kivipelto M. 2012. Journal of Alzheimer's disease. 31: 669-676 -
Practical Lessons from Amyloid Immunotherapy Trials in Alzheimer Disease
Solomon A, Akenine U, Andreasen N, Mangialasche F, Wimo A, Jelic V, Kivipelto M, Winblad B. 2012. Current alzheimer research. 9: 1126-1134 -
Structural MRI in frontotemporal dementia: Comparisons between hippocampal volumetry, tensor-based morphometry and voxel-based morphometry
Munoz-Ruiz MA, Hartikainen P, Koikkalainen J, Wolz R, Julkunen V, Niskanen E, Herukka S-K, Kivipelto M, Vanninen R, Rueckert D, Liu Y, Lötjönen J, Soininen H. 2012. PLoS ONE. 7: e52531 -
Structural brain changes and cognition in relation to markers of vascular dysfunction
Miralbell J, Soriano JJ, Spulber G, Lopez-Cancio E, Arenillas JF, Bargallo N, Galan A, Barrios MT, Caceres C, Alzamora MT, Pera G, Kivipelto M, Wahlund L-O, Davalos A, Mataro M. 2012. Neurobiology of aging. 33: 1003.e9-1003.e17 -
Voiko muistisairauksia ehkäistä?
Kivipelto M, Ngandu T, Soininen H, Laatikainen T. Teoksessa: Reivinen J, Vähäkylä L(toim.) , 2012. Kansan terveys, yksilön hyvinvointi. s. 91-107. Gaudeamus Oy -
Changes in vascular risk factors from midlife to late life and white matter lesions: A 20-year follow-up study
Vuorinen Miika, Solomon Alina, Rovio Suvi, Nieminen Lasse, Kåreholt Ingemar, Tuomilehto Jaakko, Soininen Hilkka, Kivipelto Miia. 2011. Dementia and geriatric cognitive disorders. 31: 119-125 -
Cost-effectiveness of a health intervention program with risk reductions for getting demented: Results of a Markow model in a Swedish/Finnish setting
Zhang Y, Kivipelto M, Solomon A, Wimo A. 2011. Journal of Alzheimer's disease. 26: 735-744 -
Diffusion tensor imaging and Tract-Based Spatial Statistics in Alzheimer's disease and mild cognitive impairment
Liu Y, Spulber G, Lehtimäki KK, Könönen M, Hallikainen I, Gröhn H, Kivipelto M, Hallikainen M, Vanninen R, Soininen H. 2011. Neurobiology of aging. 32: 1558-1571 -
Heavy smoking in midlife and long-term risk of Alzheimer disease and vascular dementia
Rusanen Minna, Kivipelto Miia, Quesenberry Jr Charles P, Zhou Jufen, Whitmer Rachel A. 2011. Archives of internal medicine. 171: 333-339 -
Metabolome in progression to Alzheimer's disease
Oresic M, Hyötyläinen T, Herukka S-K, Sysi-Aho M, Mattila I, Seppänan-Laakso T, Julkunen V, Gopalacharyulu PV, Hallikainen M, Koikkalainen J, Kivipelto M, Helisalmi S, Lötjönen J, Soininen H. 2011. Translational psychiatry. 1: e57 -
Midlife healthy-diet index and late-life dementia and Alzheimer's disease
Eskelinen Marjo, Ngandu Tiia, Tuomilehto Jaakko, Soininen Hilkka, Kivipelto Miia. 2011. Dementia and geriatric cognitive disorders. 1: 103-112 -
New insights into Alzheimer's disease progression: A combined TMS and structural MRI study
Niskanen Eini, Könönen Mervi, Määttä Sara, Hallikainen Merja, Kivipelto Miia, Casarotto Silvia, Massimini Marcello, Vanninen Ritva, Mervaala Esa, Karhu Jari, Soininen Hilkka. 2011. PLoS ONE. 6: e26113 -
Alzheimer's disease: clinical trials and drug development
Mangialasche F, Solomon A, Winblad B, Mecocci P & Kivipelto M. 2010. The Lancet Neurology. 9: 702-16 -
Caffeine as a protective factor in dementia and Alzheimer's Disease
Eskelinen MH, Kivipelto M. 2010. Journal of Alzheimer's disease. 20: S167-S174 -
Diabetes, Alzheimer disease, and vascular dementia: a population-based neuropathologic study
Ahtiluoto S, Polvikoski T, Peltonen M, Solomon A, Tuomilehto J, Winblad B, Sulkava R & Kivipelto M. 2010. Neurology. 75: 1195-1202 -
Differences in cortical thickness in healthy controls, subjects with mild cognitive impairment, and Alzheimer's Diseaes patients: A longitudinal study
Julkunen V, Niskanen E, Koikkalainen J, Herukka SK, Pihlajamäki M, Hallikainen H, Kivipelto M, Muehlboeck S, Evans AC, Vanninen R & Soininen H. 2010. Journal of Alzheimer's disease. 21: 1141-1151 -
HPA axis dysregulation associated to apolipoprotein E4 genotype in Alzheimer's Disease
Gil-Bea FJ, Aisa B, Solomon A, Solas M, del Carmen Mugueta M, Winblad B, Kivipelto M, Cedazo-Minguez A, Ramirez MJ. 2010. Journal of Alzheimer's disease. 22: 829-838 -
Homocysteine and holotranscobalamin and the risk of Alzheimer disease
Hooshmand B, Solomon A, Kåreholt I, Leivistä J, Rusanen M, Ahtiluoto S, Winblad B, Laatikainen T, Soininen H & Kivipelto M. 2010. Neurology. 75: 1408-1414 -
Insulin levels are decreased in the cerebrospinal fluid of womwn with prodomal Alzheimer's disease
Gil-Bea FJ, Solas M, Solomon A, Mugueta C, Winblad B, Kivipelto M, Ramirez MJ, Cedazo-Minguez A. 2010. Journal of Alzheimer's disease. 22: 405-413 -
Links between ApoE, brain cholesterol metabolism, tau and amyloid beeta-peptide in patients with cognitive impairment
Leoni V, Solomon A & Kivipelto M. 2010. Biochemical society transactions. 38: 1021-2025 -
Lipid-Lowering Treatment Is Related to Decreased Risk of Dementia: A Population-Based Study (FINRISK)
Solomon A, Sippola R, Soininen H, Wolozin B, Tuomilehto J, Laatikainen T & Kivipelto M. 2010. Neurodegenerative diseases. 7: 180-182 -
Midlife smoking, apolipoprotein E and risk of dementia and Alzheimer's disease: A population-based cardiovascular risk factors, aging and dementia study
Rusanen M, Rovio S, Ngandu T, Nissinen A, Tuomilehto J, Soininen H, Kivipelto M. 2010. Dementia and geriatric cognitive disorders. 30: 277-284 -
Muistisairaudet
Erkinjuntti T, Rinne J & Soininen H. 2010. . . WS Bookwell Oy -
Nonpharmacological therapies in Alzheimer's Disease: A systematic review of efficacy
Olazaran J, Reisberg B, Clare L, Cruz L, Pena-Casanova J, del Ser T, Woods B, Beck C, Auer S, Lai C, Spector A, Fazio S, Bond J, Kivipelto M et al.. 2010. Dementia and geriatric cognitive disorders. 30: 161-178 -
Randomized controlled trial of atorvastatin in mild to moderate Alzheimer disease: LEADe
Feldman HH, Doody RS, Kivipelto M, Sparks DL, Waters DD, Jones RW, Schwam E, Schindler R et al. 2010. Neurology. 74: 956-964 -
Stroke: Working toward to prioritized world agenda
Hachinski V, Donnan GA, Gorelick PB, Hacke W, Cramer SC, Kaste M, Fisher M, Brainin M et al. 2010. Stroke. 41: 1084-1099 -
The effect of midlife physical activity on structural brain changes in the elderly
Rovio S, Spulber G, Nieminen LJ, Niskanen E, Winblad B, Tuomilehto J, Nissinen A, Soininen H & Kivipelto M. 2010. Neurobiology of aging. 31: 1927-1936 -
Use of angiotensin receptor blockers and risk of dementia in a predominantly male population: prospective cohort analysis
Li NC, Lee A, Whitmer RA, Kivipelto M, Lawler E, Kazis LE & Wolozin B. 2010. BMJ (INTERNATIONAL). 340: 1-10 -
Whole brain atrophy rate predicts progression from MCI to Alzheimer's disease
Spulber G, Niskanen E, MacDonald S, Smilovici O, Chen K, Reiman EM, Jauhiainen AM, Hallikainen M, Tervo S, Wahlund LO, Vanninen R, Kivipelto M, Soininen H. 2010. Neurobiology of aging. 31: 1601-1605 -
Association between mid-life marital status and cognitive function in later life: population based cohort study
Håkansson K, Rovio S, Helkala E-L, Vilska A-R, Windlad B, Soininen H, Nissinen A, Mohammed AH, Kivipelto M, Soininen H. 2009. BMJ. 339: -
Cortical thickness analysis to detect progressive mild cognitive impairment: a reference to Alzheimer's disease
Julkunen V, Niskanen E, Muehlboeck S, Pihlajamäki M, Könönen M, Hallikainen M, Kivipelto M, Tervo S, Vanninen R, Evans A, Soininen H, Soininen H. 2009. Dementia and geriatric cognitive disorders. 28: 404-412 -
Midlife coffee and tea drinking and the risk of late-life dementia: a population-based CAIDE study
Eskelinen MH, Ngandu T, Tuomilehto J, Soininen H, Kivipelto M, Soininen H. 2009. Journal of Alzheimer's disease. 16: 85-91 -
Midlife serum cholesterol and increased risk of Alzheimer's and vascular dementia three decades later
Solomon A, Kivipelto M, Wolozin B, Zhou J, Whitmer RA. 2009. Dementia and geriatric cognitive disorders. 28: 75-80 -
Plasma levels of 24S-hydroxycholesterol reflect brain volumes in patients without objective cognitive impairment but not in those with Alzheimer's disease
Solomon A, Leoni V, Kivipelto M, Besga A, Öksengård AR, Julin P, Svensson L, Wahlund L-O, Andreasen N, Winbland B, Soininen H, Björkhem I, Soininen H. 2009. Neuroscience letters. : 89-93 -
Serum total cholesterol, statins and cognition in non-demented elderly
Solomon A, Kåreholt I, Ngandu T, Wolozin B, Macdonald SW, Winbland B, Nissinen A, Tuomilehto J, Soininen H, Kivipelto M, Soininen H. 2009. Neurobiology of aging. 30: 1006-1009 -
A multi-metabolite analysis of serum by 1H NMR spectroscopy: Early systemic signs of Alzheimer's disease
Tukiainen T, Tynkkynen T, Mäkinen V-P, Jylänki P, Kangas A, Hokkanen J, Vehtari A, Gröhn O, Hallikainen M, Soininen H, Kivipelto M, Groop P-H, Kaski K, Laatikainen R, Soininen P, Pirttilä T, Ala-Korpela M, Soininen H, Pirttilä. 2008. Biochemical and biophysical research communications. 375: 356-361 -
Apolipoprotein E epsilon4 allele is associated with increased atrophy in progressive mild cognitive impairment: a voxel-based morphometric study
Hämäläinen A, Grau-Olivares M, Tervo S, Niskanen E, Pennanen C, Huuskonen J, Kivipelto M, Hänninen T, Tapiola M, Vanhanen M, Hallikainen M, Helkala E-L, Nissinen A, Vanninen RL, Soininen H, Hallikainen M, Soininen H. 2008. Neurodegenerative diseases. 5: 186-189 -
Apolipoprotein E epsilon4 magnifiles lifestyle risks for dementia: a population-based study
Kivipelto M, Rovio S, Ngandu T, Kåreholt I, Eskelinen M, Wiblad B, Hachinski V, Cedazo-Minguez A, Soininen H, Tuomilehto J, Nissinen A, Soininen H. 2008. Journal of cellular and molecular medicine. 12: 2762-2771 -
Differential hypometabolism patterns according to mild cognitive impairment subtypes
Jauhiainen AM, Kangasmaa T, Rusanen M, Niskanen E, Tervo S, Kivipelto M, Vanninen RL, Kuikka JT, Soininen H, Soininen H. 2008. Dementia and geriatric cognitive disorders. 26: 490-498 -
Fat intake at midlife and cognitive impairment later in life: a population-based CAIDE study
Eskelinen MH, Ngandu T, Helkala EL, Tuomilehto J, Nissinen A, Soininen H, Kivipelto M, Soininen H. 2008. International journal of geriatric psychiatry. 23: 741-747 -
MRI of hippocampus and entorhinal cortex in mild cognitive impairment: a follow-up study
Tapiola T, Pennanen C, Tapiola M, Tervo S, Kivipelto M, Hänninen T, Pihlajamäki M, Laakso MP, Hallikainen M, Hämäläinen A, Vanhanen M, Helkala EL, Vanninen R, Nissinen A, Rossi R, Frisoni GB, Soininen H. 2008. Neurobiology of aging. 29: 31-38 -
Alcohol drinking and cognitive functions: findings from the cardiovascular risk factors aging and dementia (CAIDE) study
Ngandu T, Helkala E-L, Soininen H, Winblad B, Tuomilehto J, Nissinen A, Kivipelto M. 2007. Dementia and geriatric cognitive disorders. 23: 140-149 -
Carotid intima-media thickness and cognitive function in elderly women: a population-based study
Komulainen P, Kivipelto M, Lakka TA, Hassinen M, Helkala E-L, Patja K, Nissinen A, Rauramaa R. 2007. Neuroepidemiology. 28: 207-213 -
Education and dementia: What lies behind the association?
Ngandu T, von Strauss E, Helkala E-L, Winblad B, Nissinen A, Tuomilehto J, Soininen H, Kivipelto M, Soininen H. 2007. Neurology. 69: 1442-1450 -
Levels of ApoE in cerebrospinal fluid are correlated with Tau and 24S-hydroxycholesterol in patients with cognitive disorders
Shafaati M, Solomon A, Kivipelto M, Björkhem I, Leoni V. 2007. Neuroscience letters. 425: 78-82 -
Metabolic syndrome and cognitive function: a population-based follow-up study in elderly women
Komulainen P, Lakka TA, Kivipelto M, Hassinen M, Helkala E-L, Haapala I, Nissinen A, Rauramaa R. 2007. Dementia and geriatric cognitive disorders. 23: 29-34 -
Serum cholesterol changes after midlife and late-life cognition. Twenty-one-year follow-up study
Solomon A, Kåreholt I, Ngandu T, Winblad B, Nissinen A, Tuomilehto J, Soininen H, Kivipelto M. 2007. Neurology. 68: 751-756 -
Serum high sensitivity C-reactive protein and cognitive function in elderly women
Komulainen P, Lakka TA, Kivipelto M, Hassinen M, Penttilä IM, Helkala E-L, Gylling H, Nissinen A, Rauramaa R. 2007. Age and ageing. 36: 443-448 -
Voxel-based morphometry to detect brain atrophy in progressive mild cognitive impairment
Hämäläinen A, Tervo S, Grau-Olivares M, Niskanen E, Pennanen C, Huuskonen J, Kivipelto M, Hänninen T, Tapiola M, Vanhanen M, Hallikainen M, Helkala E-L, Nissinen A, Vanninen R, Soininen H, Hämäläinen A, Tervo S, Vanhanen M, Hallikainen M, Soininen H. 2007. Neuroimage. 37: 1122-1131 -
Work-related physical activity and the risk of dementia and Alzheimer's disease
Rovio S, Kåreholt I, Viitanen M, Winblad B, Tuomilehto J, Soininen H, Nissinen A, Kivipelto M, Soininen H. 2007. International journal of geriatric psychiatry. 22: 874-882 -
Alzheimer's Disease: back to the future
Kivipelto M, Solomon A, Winbland B. 2006. Acta neurologica scandinavica: supplementum. 114: 119-120 -
Body mass index and the risk of Parkinson disease
Hu G, Jousilahti P, Nissinen A, Antikainen R, Kivipelto M, Tuomilehto J. 2006. Neurology. 67: 1955-1959 -
Cholesterol as a risk factor for Alzheimer¿s disease - epidemiological evidence
Kivipelto M, Solomon A. 2006. Acta neurologica scandinavica: supplementum. 114: 50-57 -
Fat intake at midlife and risk of dementia and Alzheimer¿s disease: A population-based study
Laitinen MH, Ngandu T, Rovio S, Helkala E-L, Uusitalo U, Viitanen M, Nissinen A, Tuomilehto J, Soininen H, Kivipelto M. 2006. Dementia and geriatric cognitive disorders. 22: 99-107 -
Risk score for the prediction of dementia risk in 20 years among middle aged people: a longitudinal, population-based study
Kivipelto M, Ngandu T, Laatikainen T, Winblad B, Soininen H, Tuomilehto J. 2006. The Lancet Neurology. 5: 735-741 -
The effect of apolipoprotein polymorphism on brain in mild cognitive impairment: A voxel-based morphometric study
Pennanen C, Testa C, Boccardi M, Laakso MP, Hallikainen M, Helkala E-L, Hänninen T, Kivipelto M, Könönen M, Nissinen A, Tervo S, Vanhanen M, Vanninen R, Frisoni GB, Soininen H, Könönen M, Hallikainen M, Tervo S, Soininen H, Laakso MP. 2006. Dementia and geriatric cognitive disorders. 22: 60-66 -
The new cholesterol controversy - a little bit of history repeating?
Kivipelto M, Solomon A, Blennow K, Olsson AG, Winblad B. 2006. Acta neurologica scandinavica: supplementum. 114: 1-2 -
A voxel based morphometry study on mild cognitive impairment
Pennanen C, Testa C, Laakso MP, Hallikainen M, Helkala E-L, Hänninen T, Kivipelto M, Könönen M, Nissinen A, Tervo S, Vanhanen M, Vanninen R, Frisoni GB, Soininen H, Laakso MP, Könönen M, Soininen H. 2005. Journal of neurology neurosurgery and psychiatry. 76: 11-14 -
Can mild cognitive impairment predict Alzheimer¿s disease?
Soininen H, Tuomainen S, Pennanen C, Hänninen T, Kivipelto M, Soininen H. Teoksessa: Hanin I, Cacabelos R, Fisher A(toim.) , 2005. Recent Progress in Alzheimer¿s and Parkinson¿s Disease. s. 191-195. Taylor & Francis -
High cholesterol diet induces tau hyperphosphorylation in apolipoprotein E deficient mice
Rahman A, Akterin S, Flores-Morales A, Crisby M, Kivipelto M, Schultzberg M, Cedazo-Mínguez A. 2005. Febs letters. 579: 6411-6416 -
Leisure-time physical activity at midlife and the risk of dementia and Alzheimer's disease
Rovio S, Kåreholt I, Helkala E-L, Viitanen M, Winblad B, Tuomilehto J, Soininen H, Nissinen A, Kivipelto M. 2005. The Lancet Neurology. 4: 705-711 -
Obesity and vascular risk factors at midlife and the risk of dementia and Alzheimer¿s disease
Kivipelto M, Ngandu T, Fratiglioni L, Viitanen M, Kåreholt I, Winblad B, Helkala E-L, Tuomilehto J, Soininen H, Nissinen A, Soininen H. 2005. Archives of neurology. 62: 1556-1560 -
Acetylcholinesterase and its inhibition in Alzheimer Disease
Lane RM, Kivipelto M, Greig NH, Kivipelto M. 2004. Clinical neuropharmacology. 27: 141-149 -
Alcohol drinking in middle age and subsequent risk of mild cognitive impairment and dementia in old age: a prospective population based study
Anttila T, Helkala E-L, Viitanen M, Kåreholt I, Fratiglioni L, Winblad B, Soininen H, Tuomilehto J, Nissinen A, Kivipelto M, Soininen H. 2004. BMJ international edition. 329: 539-544 -
Alzheimerin taudin genetiikka
Hiltunen M, Helisalmi S, Kivipelto M, Soininen H, Hiltunen M, Helisalmi S, Soininen H. 2004. Duodecim. 120: 2425-2431 -
Hippocampus and entorhinal cortex in mild cognitive impairment and early AD
Pennanen C, Kivipelto M, Tuomainen S, Hartikainen P, Hänninen T, Laakso MP, Hallikainen M, Vanhanen M, Nissinen A, Helkala E-L, Vainio P, Vanninen R, Partanen K, Soininen H, Pennanen C, Kivipelto M, Tuomainen S, Hänninen T, Hallikainen M, Vanhanen M. 2004. Neurobiology of aging. 25: 303-310 -
Incidence and risk factors for mild cognitive impairment: a population-based three-year follow-up study of cognitively healthy elderly subjects
Tervo S, Kivipelto M, Hänninen T, Vanhanen M, Hallikainen M, Mannermaa A, Soininen H, Tervo S, Kivipelto M, Hänninen T, Vanhanen M, Hallikainen M, Soininen H. 2004. Dementia and geriatric cognitive disorders. 17: 196-203 -
Mild cognitive impairment - beyond controversies, towards a consensus: report ot the international working group on mild cognitive impairment
Winblad B, Palmer K, Kivipelto M, Jelic V, Fratiglioni L, Wahlund L-O, Nordberg A, Bäckman L, Albert M, Almkvist O, Arai H, Basun H, Blennow K, de Leon M, Decarli C, Erkinjuntti T, Giacobini E, Graff C, Hardy J, Jack C, Jorm A, Ritchie K, van Duijn C, Visser P, Petersen RC, Kivipelto M. 2004. Journal of internal medicine. 256: 240-246 -
Risk and protective effects of the APOE gene towards Alzheimer¿s disease in the Kungsholmen project: variation by age and sex
Qiu C, Kivipelto M, Aguero-Torres H, Winblad B, Fratiglioni L, Kivipelto M. 2004. Journal of neurology neurosurgery and psychiatry. 75: 828-833 -
Serum lipids and hippocampal volume: the link to Alzheimer¿s disease?
Wolf H, Hensel A, Arendt T, Kivipelto M, Winblad B, Gertz H-J, Kivipelto M. 2004. Annals of neurology. 56: 745-749 -
Serum testosterone levels in males with Alzheimer¿s disease
Pennanen C, Laakso MP, Kivipelto M, Ramberg J, Soininen H, Laakso MP, Soininen H. 2004. Journal of neuroendocrinology. 16: 95-98 -
Utilization of cognitive support in episidic free recall as a function of apolipoprotein E and vitamin B12 or folate among adults aged 75 years and older
Bunce D, Kivipelto M, Wahlin Å, Kivipelto M. 2004. Neuropsychology. 18: 362-370 -
Apolipoprotein E epsilon4 allele, elevated midlife total cholesterol level, and high midlife systolic blood pressure are independent risk factors for late-life Alzheimer disease
Kivipelto M, Helkala E-L, Laakso MP, Hänninen T, Hallikainen M, Alhainen K, Iivonen S, Mannermaa A, Tuomilehto J, Nissinen A, Soininen H. 2002. Annals of internal medicine. 137: 149-155 -
Hypertension and hypercholesterolaemia as risk factors for Alzheimer¿s disease: potential for pharmacological intervention
Kivipelto M, Laakso MP, Tuomilehto J, Nissinen A, Soininen H. 2002. Cns drugs. 16: 435-444 -
Hypertension and white matter lesions of the brain
Kivipelto M, Soininen H, Tuomilehto J. 2002. Journal of hypertension. 20: 387-389 -
Midlife income, occupation, APOE status, and dementia
Anttila T, Helkala E-L, Kivipelto M, Hallikainen M, Alhainen K, Heinonen H, Mannermaa A, Tuomilehto J, Soininen H, Nissinen A. 2002. Neurology. 59: 887-893 -
Usefulness of repeated presentation of Mini-Mental State Examination as a diagnostic procedure - a population-based study
Helkala E-L, Kivipelto M, Hallikainen M, Alhainen K, Heinonen H, Tuomilehto J, Soininen H, Nissinen A. 2002. Acta neurologica scandinavica. 106: 341-346 -
Vascular Risk Factors in Alzheimer¿s Disease and Mild Cognitive Impairment
Kivipelto M. 2002. Kuopion yliopisto. Neurologian klinikan julkaisusarja, No -
Vascular risk factors, ApoE epsilon4 allele, and gender and the risk of Alzheimer¿s disease: perspectives on prevention
Kivipelto M, Helkala E-L, Nissinen A, Soininen H, Tuomilehto J. 2002. Drug development research. 56: 85-94 -
APOE-epsilon4 is associated with weight loss in women with AD. A population-based study
Vanhanen M, Kivipelto M, Koivisto K, Kuusisto J, Mykkänen L, Helkala E-L, Hänninen T, Kervinen K, Kesäniemi YA, Laakso MP, Soininen H, Laakso M. 2001. Neurology. 56: 655-659 -
Midlife vascular risk factors and Alzheimer¿s disease in later life: longitudinal, population based study
Kivipelto M, Helkala E-L, Laakso MP, Hänninen T, Hallikainen M, Alhainen K, Soininen H, Tuomilehto J, Nissien A. 2001. BMJ international edition. 322: 1447-1451 -
Midlife vascular risk factors and late-life mild cognitive impairment. A population-based study
Kivipelto M, Helkala E-L, Hänninen T, Laakso MP, Hallikainen M, Alhainen K, Soininen H, Tuomilehto J, Nissinen A. 2001. Neurology. 56: 1683-1689