Mika Reinisalo

Hellinen, Laura; Bahrpeyma, Sina; Rimpelä, Anna-Kaisa; Hagström, Marja; Reinisalo, Mika; Urtti, Arto. 2020. Microscale Thermophoresis as a Screening Tool to Predict Melanin Binding of Drugs Pharmaceutics 12 6: 554. 2020

Fayyaz, A; Ranta, VP; Toropainen, E; Vellonen, KS; Ricci, GD; Reinisalo, M; Heikkinen, EM; Gardner, I; Urtti, A; Jamei, M; del Amo, EM. 2019. Ocular Intracameral Pharmacokinetics for a Cocktail of Timolol, Betaxolol, and Atenolol in Rabbits Molecular pharmaceutics 12 4: e007045. 2019

Hellinen, L; Hagström, M; Knuutila, H; Ruponen, M; Urtti, A; Reinisalo, M. 2019. Characterization of artificially re-pigmented ARPE-19 retinal pigment epithelial cell model Scientific reports 9 1: 13761. 2019

Hellinen, L; Pirskanen, L; Tengvall-Unadike, U; Urtti, A; Reinisalo, M. 2019. Retinal Pigment Epithelial Cell Line with Fast Differentiation and Improved Barrier Properties Pharmaceutics 11 8: 412. 2019

Hellinen, Laura; Sato, Kazuki; Reinisalo, Mika; Kidron, Heidi; Rilla, Kirsi; Tachikawa, Masanori; Uchida, Yasuo; Terasaki, Tetsuya; Urtti, Arto. 2019. Quantitative Protein Expression in the Human Retinal Pigment Epithelium: Comparison Between Apical and Basolateral Plasma Membranes With Emphasis on Transporters Investigative ophthalmology and visual science 60 15: 5022-5034. 2019

Subia, B; Reinisalo, M; Dey, N; Tavakoli, S; Subrizi, A; Ganguli, M; Ruponen, M. 2019. Nucleic acid delivery to differentiated retinal pigment epithelial cells using cell-penetrating peptide as a carrier European journal of pharmaceutics and biopharmaceutics 140: 91-99. 2019

Touloupi, K; Kublbeck, J; Magklara, A; Molnar, F; Reinisalo, M; Konstandi, M; Honkakoski, P; Pappas, P. 2019. The basis for strain-dependent rat aldehyde dehydrogenase 1A7 (ALDH1A7) gene expression Molecular pharmacology 96 5: 655-663. 2019

Felszeghy, S; Viiri, J; Paterno, JJ; Hyttinen, JMT; Koskela, A; Chen, M; Leinonen, H; Tanila, H; Kivinen, N; Koistinen, A; Toropainen, E; Amadio, M; Smedowski, A; Reinisalo, M; Winiarczyk, M; Mackiewicz, J; Mutikainen, M; Ruotsalainen, AK; Kettunen, M; Jokivarsi, K; et al [Incl Kaarniranta, K; Kauppinen, A; Kinnunen, K; Levonen, A-L; Salminen, A; Tavi, P-P; Urtti, A]. 2018. Loss of NRF-2 and PGC-1[alpha] genes leads to retinal pigment epithelium damage resembling dry age-related macular degeneration Redox biology 2019; 20: 1-12. 2018

Rimpelä, Anna-Kaisa; Reinisalo, Mika; Hellinen, Laura; Grazhdankin, Evgeni; Kidron, Heidi; Urtti Arto; del Amo, Eva M. 2018. Implications of melanin binding in ocular drug delivery ADVANCED DRUG DELIVERY REVIEWS 126: 23-43. 2018

del Amo Eva M, Rimpelä Anna-Kaisa, Heikkinen Emma, Kari Otto K, Ramsay Eva, Lajunen Tatu, Schmitt Mechthild, Pelkonen Laura, Bhattacharya Madhushree, Richardson Dominique, Subrizi Astrid, Turunen Tiina, Reinisalo Mika, Itkonen Jaakko, Toropainen Elisa, Casteleijn Marco, Kidron Heidi, Antopolsky Maxim, Vellonen Kati-Sisko, Ruponen Marika, et al.. 2017. Pharmacokinetic aspects of retinal drug delivery PROGRESS IN RETINAL AND EYE RESEARCH 57: 134-185. 2017

Juuti-Uusitalo K, Koskela A, Kivinen N, Viiri J, Hyttinen JMT, Reinisalo M, Koistinen A, Uusitalo H, Sinha D, Skottman H, Kaarniranta K. 2017. Autophagy Regulates Proteasome Inhibitor-Induced Pigmentation in Human Embryonic Stem Cell-Derived Retinal Pigment Epithelial Cells. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 18 5: 1089. 2017

Pelkonen L, Sato K, Reinisalo M, Kidron H, Tachikawa M, Watanabe M, Uchida Y, Urtti A, Terasaki T. 2017. LC-MS/MS Based Quantitation of ABC and SLC Transporter Proteins in Plasma Membranes of Cultured Primary Human Retinal Pigment Epithelium Cells and Immortalized ARPE19 Cell Line. Molecular Pharmaceutics 14 3: 605-613. 2017

Pelkonen L, Tengvall-Unadike U, Ruponen M, Kidron H, del Amo EM, Reinisalo M, Urtti A. 2017. Melanin binding study of clinical drugs with cassette dosing and rapid equilibrium dialysis inserts. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES 109: 162-168. 2017

Hakkarainen Jenni J, Reinisalo Mika, Ragauskas Symantas, Seppänen Aila, Kaja Simon, Kalesnykas Giedrius. 2016. Acute cytotoxic effects of marketed ophthalmic formulations on human corneal epithelial cells. INTERNATIONAL JOURNAL OF PHARMACEUTICS 511 1: 73-78. 2016

Koskela Ali, Reinisalo Mika, Petrovski Goran, Sinha Debasish, Olmiere Céline, Karjalainen Reijo, Kaarniranta Kai. 2016. Nutraceutical with Resveratrol and Omega-3 Fatty Acids Induces Autophagy in ARPE-19 Cells. Nutrients 8 5: 284. 2016

Pelkonen Laura, Reinisalo Mika, Morin-Picardat Emmanuelle, Kidron Heidi, Urtti Arto. 2016. Isolation of Intact and Functional Melanosomes from the Retinal Pigment Epithelium. PLOS ONE 11 8: e0160352. 2016

Reinisalo Mika, Kårlund Anna, Koskela Ali, Kaaniranta Kai, Karjalainen Reijo O.. 2015. Polyphenol Stilbenes: Molecular Mechanisms of Defence against Oxidative Stress and Aging-Related Diseases. Oxidative Medicine and Cellular Longevity 2015, Article ID 340520: 24 p.. 2015

Koskela Ali, Reinisalo Mika, Hyttinen Juha MT, Kaarniranta Kai, Karjalainen Reijo O. 2014. Pinosylvin-mediated protection against oxidative stress in human retinal pigment epithelial cells. MOLECULAR VISION [ONLINE: HTTP://WWW.MOLVIS.ORG/MOLVIS/] 20: 760-769. 2014

Reinisalo Mika, Putula Jaana, Mannermaa Eliisa, Urtti Arto, Honkakoski Paavo. 2012. Regulation of the human tyrosinase gene in retinal pigment epithelium cells: the significance of transcription factor orthodenticle homeobox 2 and its polymorphic binding site MOLECULAR VISION [ONLINE: HTTP://WWW.MOLVIS.ORG/MOLVIS/] 18: 38-54. 2012

Reinisalo Mika. 2012. Studies on Retina-specific Gene Expression. Publications of the University of Eastern Finland. Dissertations in Health Sciences 119. 2012

Kauppinen Ari, Reinisalo Mika, Pellinen Riikka, Korhonen Ossi, Järvinen Kristiina, Ketolainen Jarkko. 2010. Effect of freeze-drying conditions on transfection efficiency of cationic polymer DNA complexes. In: (ed.) , The XXI Symposium of the Finnish Society of Physical Pharmacy. ss. 50. 2010

Küblbeck J, Reinisalo M, Mustonen R & Honkakoski P. 2010. Up-regulation of CYP expression in hepatoma cells stably transfected by chimeric nuclear receptors. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES 40: 263-272. 2010

Mannermaa E, Reinisalo M, Ranta V-P, Vellonen K-S, Kokki H, Saarikko A, Kaarniranta K & Urtti A. 2010. Filter-cultured ARPE-19 cells as outer blood-retinal barrier model. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES 40: 289-296. 2010

Kauppinen Ari, Reinisalo Mika, Pellinen Riikka, Gieseler Henning, Schneid Stefan, Rutzinger Susanne, Beirowski Jakob, Korhonen Ossi, Järvinen Kristiina, Ketolainen Jarkko. 2009. Determining the critical properties of formulations for freeze drying by DSC and FDM, 4th FinPharmaNet. 1. 2009

Ruponen M, Arkko S, Urtti A, Reinisalo M, Ranta V-P. 2009. Intracellular DNA release and elimination correlate poorly with transgene expression after non-viral transfection. JOURNAL OF CONTROLLED RELEASE 136: 226-231. 2009

Huuskonen P, Storvik M, Reinisalo M, Honkakoski P, Rysä J, Hakkola J, Pasanen M. 2008. Microarray analysis of the global alterations in the gene expression in the placentas from cigarette-smoking mothers. CLINICAL PHARMACOLOGY AND THERAPEUTICS 83: 542-550. 2008

Männistö M, Reinisalo M, Ruponen M, Honkakoski P, Tammi M, Urtti A. 2007. Polyplex-mediated gene transfer and cell cycle: effect of carrier on cellular uptake and intracellular kinetics, and significance of glycosaminoglycans. JOURNAL OF GENE MEDICINE 9: 479-487. 2007

Reinisalo M, Urtti A, Honkakoski P. 2006. Freeze-drying of cationic polymer DNA complexes enables their long-term storage and reverse transfection of post-mitotic cells JOURNAL OF CONTROLLED RELEASE 110: 437-443. 2006

Korjamo T, Honkakoski P, Toppinen M-R, Niva S, Reinisalo M, Palmgrén JJ, Mönkkönen J. 2005. Absorption properties and P-glycoprotein activity of modified Caco-2 cell lines. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES 26: 266-279. 2005

Mannermaa E, Rönkkö S, Ruponen M, Reinisalo M, Urtti A. 2005. Long-lasting secretion of transgene product from differentiated and filter-grown retinal pigment epithelial cells after nonviral gene transfer. CURRENT EYE RESEARCH 30: 345-353. 2005

Mäkinen J, Reinisalo M, Niemi K, Viitala P, Jyrkkärinne J, Chung H, Pelkonen O, Honkakoski P. 2003. Dual action of oestrogens on the mouse constitutive androstane receptor BIOCHEMICAL JOURNAL 376: 465-472. 2003

Reinisalo M, Urtti A, Honkakoski P. 2003. Retina-specific gene expression and improved DNA transfection in WERI-Rb1 retinoblastoma cells. BIOCHIMICA ET BIOPHYSICA ACTA - GENE STRUCTURE AND EXPRESSION 1628: 169-176. 2003

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