Mikko Kettunen

Ahl, Matilda; Avdic, Una; Chary, Karthik; Shibata, Keisuke; Chugh, Deepti; Lindén Mickelsson, Pernilla; Kettunen, Mikko; Compagno Strandberg, Maria; Johansson, Ulrica Englund; Sierra, Alejandra; Ekdahl, Christine T. 2021. Inflammatory reaction in the retina after focal non-convulsive status epilepticus in mice investigated with high resolution magnetic resonance and diffusion tensor imaging Epilepsy research 176: 106730. 2021

Hyppönen, Viivi; Stenroos, Petteri; Nivajärvi, Riikka; Ardenkjaer-Larsen, Jan Henrik; Gröhn, Olli; Paasonen, Jaakko; Kettunen, Mikko I. 2021. Metabolism of hyperpolarised [1-13C]pyruvate in awake and anaesthetised rat brains Nmr in biomedicine 2022; 35 2: e4635. 2021

Bassetto M, Ajoy D, Poulhes F, Obringer C, Walter A, Messadeq N, Sadeghi A, Puranen J, Ruponen M, Kettunen M, Toropainen E, Urtti A, Dollfus H, Zelphati O, Marion V. 2021. Magnetically Assisted Drug Delivery of Topical Eye Drops Maintains Retinal Function In Vivo in Mice Pharmaceutics 13 10: 1650. 2021

Hanhela, Matti; Gröhn, Olli; Kettunen, Mikko; Niinimäki, Kati; Vauhkonen, Marko; Kolehmainen, Ville. 2021. Data-Driven Regularization Parameter Selection in Dynamic MRI Journal of imaging 7 2: 38. 2021

Grotell, Milo; den Hollander, Bjørnar; Jalkanen, Aaro; Törrönen, Essi; Ihalainen, Jouni; de Miguel, Elena; Dudek, Mateusz; Kettunen, Mikko I; Hyytiä, Petri; Forsberg, Markus M; Kankuri, Esko; Korpi, Esa R. 2021. Alcohol Co-Administration Changes Mephedrone-Induced Alterations of Neuronal Activity Frontiers in pharmacology 12: 679579. 2021

Hanhela, Matti; Kettunen, Mikko; Gröhn, Olli; Vauhkonen, Marko; Kolehmainen, Ville. 2020. Temporal Huber Regularization for DCE-MRI Journal of mathematical imaging and vision 62: 1334-1346. 2020

Melone, Lucio; Bach, Alice; Lamura, Gianrico; Canepa, Fabio; Nivajärvi, Riikka; Olsson, Venla; Kettunen, Mikko. 2020. Cyclodextrin-based organic radical contrast agents for in vivo imaging of glioma ChemPlusChem 85 6: 1171-1178. 2020

Nivajärvi, R; Olsson, V; Hyppönen, V; Bowen, S; Leinonen, HM; Lesch, HP; Ardenkjaer-Larsen, JH; Gröhn, OHJ; Ylä-Herttuala, S; Kettunen, MI. 2020. Detection of lentiviral suicide gene therapy in C6 rat glioma using hyperpolarised [1-13 C]pyruvate Nmr in biomedicine 33 4: e4250. 2020

Soikkeli, Maiju; Kettunen, Mikko I; Nivajärvi, Riikka; Olsson, Venla; Rönkkö, Seppo; Laakkonen, Johanna P; Lehto, Vesa-Pekka; Kavakka, Jari; Heikkinen, Sami. 2019. Assessment of the Relaxation-Enhancing Properties of a Nitroxide-Based Contrast Agent TEEPO-Glc with In Vivo Magnetic Resonance Imaging Contrast media and molecular imaging 2019: 5629597. 2019

Hyperpolarized MRI for Studying Tumor Metabolism. Kettunen, Mikko I / Cancer Metabolism. 2019. 2019

Choo, Xin Yi; Liddell, Jeffrey R; Huuskonen, Mikko T; Grubman, Alexandra; Moujalled, Diane; Roberts, Jessica; Kysenius, Kai; Patten, Lauren; Quek, Hazel; Oikari, Lotta E; Duncan, Clare; James, Simon A; McInnes, Lachlan E; Hayne, David J; Donnelly, Paul S; Pollari, Eveliina; Vähätalo, Suvi; Lejavová, Katarína; Kettunen, Mikko I; Malm, Tarja; et al. [Incl Koistinaho, Jari; Kanninen, Katja]. 2018. CuII(atsm) Attenuates Neuroinflammation Frontiers in neuroscience 12: 668. 2018

Felszeghy, S; Viiri, J; Paterno, JJ; Hyttinen, JMT; Koskela, A; Chen, M; Leinonen, H; Tanila, H; Kivinen, N; Koistinen, A; Toropainen, E; Amadio, M; Smedowski, A; Reinisalo, M; Winiarczyk, M; Mackiewicz, J; Mutikainen, M; Ruotsalainen, AK; Kettunen, M; Jokivarsi, K; et al [Incl Kaarniranta, K; Kauppinen, A; Kinnunen, K; Levonen, A-L; Salminen, A; Tavi, P-P; Urtti, A]. 2018. Loss of NRF-2 and PGC-1[alpha] genes leads to retinal pigment epithelium damage resembling dry age-related macular degeneration Redox biology 2019; 20: 1-12. 2018

Näkki, S; Wang, JT; Wu, J; Fan, L; Rantanen, J; Nissinen, T; Kettunen, MI; Backholm, M; Ras, RHA; Al-Jamal, KT; Lehto, VP; Xu, W. 2018. Designed inorganic porous nanovector with controlled release and MRI features for safe administration of doxorubicin INTERNATIONAL JOURNAL OF PHARMACEUTICS 2019; 554: 327-336. 2018

Rasch, Julian; Kolehmainen, Ville; Nivajärvi, Riikka; Kettunen, Mikko; Grohn, Olli; Burger, Martin; Brinkmann, Eva-Maria. 2018. Dynamic MRI reconstruction from undersampled data with an anatomical prescan INVERSE PROBLEMS 34 7: 074001. 2018

Serrao, EM; Kettunen, MI; Rodrigues, TB; Lewis, DY; Gallagher, FA; Hu, DE; Brindle, KM. 2018. Analysis of 13 C and 14 C labeling in pyruvate and lactate in tumor and blood of lymphoma-bearing mice injected with 13 C- and 14 C-labeled pyruvate Nmr in biomedicine 31 5: e3901. 2018

State estimation in dynamic MRI. Wettenhovi, Ville-Veikko; Kolehmainen, Ville; Huttunen, Joanna; Kettunen, Mikko; Gröhn, Olli; Vauhkonen, Marko / 2018 IEEE Nuclear Science Symposium and Medical Imaging (NSS/MIC): Conference Proceedings. 2018. 2018

Zou J, Peng B, Ostrovsky S, Li B, Li C, Kettunen MI, Lellouche JP, Pyykkö I. 2017. Biological Effect Tetra-Branched Anti-TNF-Peptide and Coating Ratio-Dependent Penetration of the Peptide-Conjugated Cerium3/4+ Cation-Stabilized Gamma-Maghemite Nanoparticles into Rat Inner Ear after Transtympanic Injection Visualized By MRI. Journal of Materials Science & NanotechnologyAbstractObjective: 5 2: 204. 2017

Abdurakhmanova Shamsiiat, Chary Karthik, Kettunen Mikko, Sierra Alejandra, Panula Pertti. 2017. Behavioral and stereological characterization of Hdc KO mice: Relation to Tourette syndrome. JOURNAL OF COMPARATIVE NEUROLOGY 525 16: 3476-3487. 2017

Wettenhovi Ville-Veikko, Kolehmainen Ville, Huttunen Joanna, Kettunen Mikko, Gröhn Olli, Vauhkonen Marko. 2017. State Estimation with Structural Priors in fMRI. Journal of Mathematical Imaging and Vision 2018; 60 2: 174-188. 2017

Neves AA, Wainman Y A, Wright A, Kettunen MI, Rodrigues TB, McGuire S, Hu D-E, Bulat F, Geninatti Crich S, Stöckmann S, Leeper F J, Brindle KM. 2016. Imaging Glycosylation In Vivo by Metabolic Labeling and Magnetic Resonance Imaging. ANGEWANDTE CHEMIE (INTERNATIONAL ED. IN ENGLISH) 55 4: 1286-1290. 2016

Nissinen Tuomo, Näkki Simo, Laakso Hanne, Kuciauskas Dalius, Kaupinis Algirdas, Kettunen Mikko I, Liimatainen Timo, Hyvönen Mervi, Valius Mindaugas, Gröhn Olli, Lehto Vesa-Pekka. 2016. Tailored Dual PEGylation of Inorganic Porous Nanocarriers for Extremely Long Blood Circulation in Vivo. ACS Applied Materials & Interfaces 8 48: 32723-32731. 2016

Pirttimäki T, Salo RA, Shatillo A, Kettunen MI, Paasonen J, Sierra A, Jokivarsi K, Leinonen V, Andrade P, Quittek S, Pitkänen A, Gröhn O. 2016. Implantable RF-coil with multiple electrodes for long-term EEG-fMRI monitoring in rodents. JOURNAL OF NEUROSCIENCE METHODS 274: 154-163. 2016

Serrao EM, Rodrigues TB, Gallagher FA, Kettunen MI, Kennedy BWC, Vowler SL, Burling KA, Brindle KM. 2016. Effects of fasting on serial measurements of hyperpolarized [1-13C]pyruvate metabolism in tumors. NMR IN BIOMEDICINE 29 8: 1048-1055. 2016

Zou Jing, Ostrovsky Stella, Israel Liron L, Feng Hao, Kettunen Mikko I, Lellouche Jean-Paul (Moshe), Pyykkö Ilmari. 2016. Efficient penetration of ceric ammonium nitrate oxidant-stabilized gamma-maghemite nanoparticles through the oval and round windows into the rat inner ear as demonstrated by MRI. JOURNAL OF BIOMEDICAL MATERIALS RESEARCH B. APPLIED BIOMATERIALS 105 7: 1883-1891. 2016

Dzien Piotr, Kettunen Mikko I, Marco-Rius Irene, Serrao Eva M, Rodrigues Tiago B, Larkin Timothy J, Timm Kerstin N, Brindle Kevin M. 2015. 13C magnetic resonance spectroscopic imaging of hyperpolarized [1-13C, U-2H5] ethanol oxidation can be used to assess aldehyde dehydrogenase activity in vivo. MAGNETIC RESONANCE IN MEDICINE 73 5: 1733-1740. 2015

Dzien Piotr, Tee Sui-Seng, Kettunen Mikko I, Lyons Scott K., Larkin Timothy J, Timm Kerstin, Hu De-En, Wright Alan, Rodrigues Tiago B, Serrao Eva M, Marco-Rius Irene, Mannion Elizabeth, D'Santos Paula, Kennedy Brett W.C, Brindle Kevin M. 2015. 13C magnetic resonance spectroscopy measurements with hyperpolarized [1-13C] pyruvate can be used to detect the expression of transgenic pyruvate decarboxylase activity in vivo. MAGNETIC RESONANCE IN MEDICINE [Epub ahead of print 21 SEP 2015]. 2015

Serrao Eva M, Kettunen Mikko I, Rodrigues Tiago B, Dzien Piotr, Wright Alan J, Gopinathan Aarthi, Gallagher Ferdia A, Lewis David Y, Frese Kristopher K, Almeida Jaime, Howat William J, Tuveson David A, Brindle Kevin M. 2015. MRI with hyperpolarised [1-13C]pyruvate detects advanced pancreatic preneoplasia prior to invasive disease in a mouse model. GUT 65 3 (2016): 465-475. 2015

Timm Kerstin N, Hartl Johannes, Keller Markus A, Hu De-En, Kettunen Mikko I, Rodrigues Tiago B, Ralser Markus, Brindle Kevin M. 2015. Hyperpolarized [U-2H, U-13C]Glucose reports on glycolytic and pentose phosphate pathway activity in EL4 tumors and glycolytic activity in yeast cells. MAGNETIC RESONANCE IN MEDICINE 74 6: 1543-1547. 2015

Patrick PS, Kettunen MI, Tee SS, Rodrigues TB, Serrao E, Timm KN, McGuire S, Brindle KM. 2014. Detection of transgene expression using hyperpolarized 13 C urea and diffusion-weighted magnetic resonance spectroscopy. MAGNETIC RESONANCE IN MEDICINE Epub 14 APR 2014: --. 2014

Kettunen MI, Sierra A, Närväinen MJ, Valonen PK, Ylä-Herttuala S, Kauppinen RA, Gröhn OHJ. 2007. Low spin-lock field T1 relaxation in the rotating frame as a sensitive MR imaging marker for gene therapy treatment response in rat glioma. RADIOLOGY 243: 796-803. 2007

Pirinen E, Kuulasmaa T, Pietilä M, Heikkinen S, Tusa M, Itkonen P, Boman S, Skommer J, Virkamäki A, Hohtola E, Kettunen M, Fatrai S, Kansanen E, Koota S, Niiranen K, Parkkinen J, Levonen A-L, Ylä-Herttuala S, Hiltunen JK, Alhonen L, Smith U, Jänne J. 2007. Enhanced polyamine catabolism alters homeostatic control of white adipose tissue mass, energy expenditure, and glucose metabolism MOLECULAR AND CELLULAR BIOLOGY 27 13: 4953-4967. 2007

Siiskonen H, Oikari S, Korhonen V-P, Pitkänen A, Voikar V, Kettunen M, Hakumäki J, Wahlfors T, Pussinen R, Penttonen M, Kiehne K, Kaasinen SK, Alhonen L, Jänne J, Herzig K-H. 2007. Diazepam binding inhibitor overexpression in mice causes hydrocephalus, decreases plasticity in excitatory synapses and impairs hippocamus-depend learning. MOLECULAR AND CELLULAR NEUROSCIENCE (SAN DIEGO CA) 34 2: 199-208. 2007

Yrjänheikki J, Koistinaho J, Kettunen M, Kauppinen RA, Appel K, Hüll M, Fiebich BL. 2005. Long-term protective effect of atorvastatin in permanent focal cerebral ischemia. BRAIN RESEARCH 1052 2: 174-179. 2005

Kettunen MI, Kauppinen RA, Gröhn OHJ. 2005. Dispersion of cerebral on-resonance T1 in the rotating frame (T1 rho) in global ischaemia. APPLIED MAGNETIC RESONANCE 29: 89-106. 2005

Kettunen MI, Gröhn OHJ. 2005. Tumour gene therapy monitoring using magnetic resonance imaging and spectroscopy. CURRENT GENE THERAPY 5: 685-696. 2005

Koistinaho M, Malm TM, Kettunen MI, Goldsteins G, Starckx S, Kauppinen RA, Opdenakker G, Koistinaho J. 2005. Minocycline protects against permanent cerebral ischemia in wild type but not in matrix metalloprotease-9-deficient mice JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM 25: 460-467. 2005

Kavec M, Gröhn OHJ, Kettunen MI, Silvennoinen MJ, Garwood M, Kauppinen RA. 2004. Acute cerebral ischemia in rats studied by Carr-Purcell spin-echo magnetic resonance imaging: Assessment of blood oxygenation level-dependent and tissue effects on the transverse relaxation. MAGNETIC RESONANCE IN MEDICINE 51 6: 1138-1146. 2004

Kettunen MI, Gröhn OHJ, Kauppinen RA. 2004. Quantitative T1rho NMR spectroscopy of rat cerebral metabolites in vivo: Effects of global ischemia. MAGNETIC RESONANCE IN MEDICINE 51 5: 875-880. 2004

Mäkelä HI, De Vita E, Gröhn OHJ, Kettunen MI, Kavec M, Lythgoe M, Garwood M, Ordidge R, Kauppinen RA. 2004. B0 dependence of the on-resonance longitudinal relaxation time in the rotating frame (T1rho) in protein phantoms and rat brain in vivo. MAGNETIC RESONANCE IN MEDICINE 51 1: 4-8. 2004

Nairismägi J, Gröhn OHJ, Kettunen MI, Nissinen J, Kauppinen RA, Pitkänen A. 2004. Progression of brain damage after status epilepticus and its association with epileptogenesis: a quantitative MRI study in a rat model of temporal lobe epilepy EPILEPSIA (NY) 45 9: 1024-1034. 2004

Utriainen A, Sormunen R, Kettunen M, Carvalhaes LS, Sajanti E, Eklund L, Kauppinen R, Kitten GT, Pihlajaniemi T. 2004. Structurally altered basement membranes and hydrocephalus in a type XVIII collagen deficient mouse line. HUMAN MOLECULAR GENETICS 13 18: 2089-2099. 2004

Valonen PK, Lehtimäki KK, Väisänen TH, Kettunen MI, Gröhn OHJ, Ylä-Herttuala S, Kauppinen RA. 2004. Water diffusion in a rat glioma during ganciclovir-thymidine kinase gene therapy-induced programmed cell death in vivo: Correlation with cell density JOURNAL OF MAGNETIC RESONANCE IMAGING 19 4: 389-396. 2004

Rissanen TT, Markkanen JE, Gruchala M, Heikura T, Puranen A, Kettunen MI, Kholová I, Kauppinen RA, Achen MG, Stacker SA, Alitalo K, Ylä-Herttuala S. 2003. VEGF-D is the strongest angiogenic and lymphangiogenic effector among VEGFs delivered into skeletal muscle via adenoviruses CIRCULATION RESEARCH 92: 1098-1106. 2003

Silvennoinen MJ, Kettunen MI, Kauppinen RA. 2003. Effects of hematocrit and oxygen saturation level on blood spin-lattice relaxation. MAGNETIC RESONANCE IN MEDICINE 49 3: 568-571. 2003

Gröhn OHJ, Valonen PK, Lehtimäki KK, Väisänen TH, Kettunen MI, Ylä-Herttuala S, Kauppinen RA, Garwood M. 2003. Novel magnetic resonance imaging contrasts for monitoring response to gene therapy in rat glioma. CANCER RESEARCH 63: 7571-7574. 2003

Rissanen TT, Markkanen JE, Arve K, Rutanen J, Kettunen MI, Vajanto I, Jauhiainen S, Cashion L, Gruchala M, Närvänen O, Taipale P, Kauppinen RA, Rubanyi GM, Ylä-Herttuala S. 2003. Fibroblast growth factor-4 induces vascular permeability, angiogenesis, and arteriogenesis in a rabbit hind limb ischemia model. FASEB JOURNAL 17: 100-102. 2003

Lehtimäki KK, Valonen PK, Griffin JL, Väisänen TH, Gröhn OHJ, Kettunen MI, Vepsäläinen J, Ylä-Herttuala S, Nicholson J, Kauppinen RA. 2003. Metabolite changes in BT4C rat gliomas undergoing ganciclovir-thymidine kinase gene therapy-induced programmed cell death as studied by 1H NMR spectroscopy in vivo, ex vivo, and in vitro*. JOURNAL OF BIOLOGICAL CHEMISTRY 278 46: 45915-45923. 2003

Griffin JL, Lehtimäki KK, Valonen PK, Gröhn OHJ, Kettunen MI, Ylä-Herttuala S, Pitkänen A, Nicholson JK, Kauppinen RA. 2003. Assignment of 1H nuclear magnetic resonance visible polyunsaturated fatty acids in BT4C gliomas undergoing ganciclovir-thymidine kinase gene therapy-induced programmed cell death. CANCER RESEARCH 63: 3195-3201. 2003

Mäkelä HI, Kettunen MI, Gröhn OHJ, Kauppinen RA. 2002. Quantitative T (1rho) and magnetization transfer magnetic resonance imaging of acute cerebral ischemia in the rat. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM 22 5: 547-558. 2002

Silvennonen MJ, Kettunen MI, Clingman CS, Kauppinen RA. 2002. Blood NMR relaxation in the rotating frame: mechanistic implications. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 405 1: 78-86. 2002

Rissanen TT, Vajanto I, Hiltunen MO, Rutanen J, Kettunen MI, Niemi M, Leppänen P, Turunen MP, Markkanen JE, Arve K, Alhava E, Kauppinen RA, Ylä-Herttuala S. 2002. Expression of vascular endothelial growth factor and vascular endothelial growth factor receptor-2 (KDR/Flk-1) in ischemic skeletal muscle and its regeneration. AMERICAN JOURNAL OF PATHOLOGY 160 4: 1393-1403. 2002

Pulkkanen KJ, Laukkanen JM, Fuxe J, Kettunen MI, Rehn M, Kannasto JM, Parkkinen JJ, Kauppinen RA, Pettersson RF, Yla-Herttuala S. 2002. The combination of HSV-tk and endostatin gene therapy eradicates orthotopic human renal cell carcinomas in nude mice CANCER GENE THERAPY 9: 908-916. 2002

Kettunen MI, Gröhn OHJ, Silvennoinen MJ, Penttonen M, Kauppinen RA. 2002. Quantitative assessment of the balance between oxygen delivery and consumption in the rat brain after transient ischemia with T2-BOLD magnetic resonance imaging. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM 22 3: 262-270. 2002

Koistinaho M, Kettunen MI, Holtzman DM, Kauppinen RA, Higgins LS, Koistinaho J. 2002. Expression of human apolipoprotein E downregulates amyloid precursor protein-induced ischemic susceptibility STROKE 33: 1905-1910. 2002

Koistinaho M, Kettunen MI, Goldsteins G, Keinänen R, Salminen A, Ort M, Bures J, Liu D, Kauppinen RA, Higgins LS, Koistinaho J. 2002. Beta-amyloid precursor protein transgenic mice that harbor diffuse A beta deposits but do not form plaques show increased ischemic vulnerability: Role of inflammation. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 99 3: 1610-1615. 2002

Kettunen MI, Gröhn OHJ, Silvennoinen MJ, Penttonen M, Kauppinen RA. 2002. Effects of intracellular pH, blood, and tissue oxygen tension on T-1rho relaxation in rat brain. MAGNETIC RESONANCE IN MEDICINE 48 3: 470-477. 2002

Kettunen M. 2002. A Study of Magnetic Resonance Imaging Contrast Generation and Pathophysiology in Acute Cerebral Ischaemia. Kuopion yliopiston julkaisuja G.- A.I. Virtanen -instituutti. 2002

Karkkainen MJ, Saaristo A, Jussila L, Karila KA, Lawrence EC, Pajusola K, Bueler H, Eichmann A, Kauppinen R, Kettunen MI, Ylä-Herttuala S, Finegold DN, Ferrell RE, Alitalo K. 2001. A model for gene therapy of human hereditary lymphedema. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 98 22: 12677-12682. 2001

Kavec M, Gröhn OHJ, Kettunen MI, Silvennoinen MJ, Penttonen M, Kauppinen RA. 2001. Use of spin echo T2 BOLD in assessment of cerebral misery perfusion at 1.5 T. MAGNETIC RESONANCE MATERIALS IN PHYSICS, BIOLOGY AND MEDICINE 12: 32-39. 2001

Kettunen MI, Gröhn OHJ, Penttonen M, Kauppinen RA. 2001. Cerebral T1rho relaxation time increases immediately upon global ischemia in the rat independently of blood glucose and anoxic depolarization MAGNETIC RESONANCE IN MEDICINE 46: 565-572. 2001

Mäkelä HI, Gröhn OHJ, Kettunen MI, Kauppinen RA. 2001. Proton exchange as a relaxation mechanism for T1 in the rotating frame in native and immobilized protein solutions. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 289: 813-818. 2001

Mäkinen T, Jussila L, Veikkola T, Karpanen T, Kettunen MI, Pulkkanen KJ, Kauppinen R, Jackson DG, Kubo H, Nishikawa S-I, Ylä-Herttuala S, Alitalo K. 2001. Inhibition of lymphangiogenesis with resulting lymphedema in transgenic mice expressing soluble VEGF receptor-3 NATURE MEDICINE 7 2: 199-205. 2001

Pulkkanen KJ, Parkkinen JJ, Laukkanen JM, Kettunen MI, Tyynela K, Kauppinen RA, Ala-Opas MY, Yla-Herttuala S. 2001. HSV-tk gene therapy for human renal cell carcinoma in nude mice. CANCER GENE THERAPY 8: 529-536. 2001

Gröhn OHJ, Kettunen MI, Mäkelä HI, Penttonen M, Pitkänen A, Lukkarinen JA, Kauppinen RA. 2000. Early detection of irreversible cerebral ischemia in the rat using dispersion of the magnetic resonance imaging relaxation time, T1rho. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM 20: 1457-1466. 2000

Gröhn OHJ, Kettunen MI, Penttonen M, Oja JME, van Zijl PCM, Kauppinen RA. 2000. Graded reduction of cerebral blood flow in rat as detected by the nuclear magnetic resonance relaxation time T2: a theoretical and experimental approach JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM 20: 316-326. 2000

Kettunen MI, Gröhn OHJ, Lukkarinen JA, Vainio P, Silvennoinen MJ, Kauppinen RA. 2000. Interrelations of T1 and diffusion of water in acute cerebral ischemia of the rat MAGNETIC RESONANCE IN MEDICINE 44: 833-839. 2000

Pulkkanen KJ, Parkkinen JJ, Kettunen MI, Kauppinen RA, Lappalainen M, Ala-Opas MY, Ylä-Herttuala S. 2000. Characterization of a new animal model for human renal cell carcinoma. IN VIVO (ATHENS) 14: 393-400. 2000

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