Mikko Laitaoja - UEFConnect

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Bioorganic Chemistry 01.01.2010 -

Publications

18/18 items

One ring closer to a closure: the crystal structure of the ES3 hydroxymethylbilane synthase intermediate
Bustad, Helene J; Christie, Marthe S; Laitaoja, Mikko; Aarsand, Aasne K; Martinez, Aurora; Jänis, Janne; Kallio, Juha P. 2023. Febs journal. 2024; 291: 510-526
Primary structure determination and physicochemical characterization of DSP-3, a phosphatidylcholine binding glycoprotein of donkey seminal plasma
Alim, Sk; Laitaoja, Mikko; Pawar, Sonali; Talluri, Thirumala Rao; Jänis, Janne; Swamy, Musti J. 2023. International journal of biological macromolecules. 239:
Biochemical and Biophysical Characterization of Carbonic Anhydrase VI from Human Milk and Saliva
Yrjänäinen, Alma; Patrikainen, Maarit S; Azizi, Latifeh; Tolvanen, Martti EE; Laitaoja, Mikko; Jänis, Janne; Hytönen, Vesa P; Nocentini, Alessio; Supuran, Claudiu T; Parkkila, Seppo. 2022. Protein journal. 41: 489-503
Characterisation of a common hotspot variant in acute intermittent porphyria sheds light on the mechanism of hydroxymethylbilane synthase function
Christie, Marthe S; Laitaoja, Mikko; Aarsand, Aasne K; Kallio, Juha P; Bustad, Helene J. 2022. FEBS open bio. 12: 2136-2146
Crystal structure of the collagen prolyl 4-hydroxylase (C-P4H) catalytic domain complexed with PDI: towards a model of the C-P4H α2β2 tetramer
Murthy, Abhinandan V; Sulu, Ramita; Lebedev, Andrey; Salo, Antti M; Korhonen, Kati; Venkatesan, Rajaram; Tu, Hongmin; Bergmann, Ulrich; Jänis, Janne; Laitaoja, Mikko; Ruddock, Lloyd; Myllyharju, Johanna; Koski, M Kristian; Wierenga, Rik K. 2022. Journal of biological chemistry. 298:
Characterization of porphobilinogen deaminase mutants reveals that arginine-173 is crucial for polypyrrole elongation mechanism
Bustad, Helene J; Kallio, Juha P; Laitaoja, Mikko; Toska, Karen; Kursula, Inari; Martinez, Aurora; Jänis, Janne. 2021. iScience. 24: 102152
Purification, molecular characterization and ligand binding properties of the major donkey seminal plasma protein DSP-1
Alim, Sk; Cheppali, Sudheer K; Laitaoja, Mikko; Talluri, Thirumala Rao; Jänis, Janne; Swamy, Musti J. 2021. International journal of biological macromolecules. 2022; 194: 213-222
Structural insights into the substrate-binding proteins Mce1A and Mce4A from Mycobacterium tuberculosis
Asthana, Pooja; Singh, Dhirendra; Pedersen, Jan Skov; Hynönen, Mikko J.; Sulu, Ramita; Murthy, Abhinandan V.; Laitaoja, Mikko; Jänis, Janne; Riley, Lee W.; Venkatesan, Rajaram. 2021. IUCrJ. 8: 757 - 774
The F1 loop of the talin head domain acts as a gatekeeper in integrin activation and clustering
Kukkurainen, Sampo; Azizi, Latifeh; Zhang, Pingfeng; Jacquier, Marie-Claude; Baikoghli, Mo; von Essen, Magdaléna; Tuukkanen, Anne; Laitaoja, Mikko; Liu, Xiaonan; Rahikainen, Rolle; Orlowski, Adam; Jänis, Janne; Määttä, Juha AE; Varjosalo, Markku; Vattulainen, Ilpo; Róg, Tomasz; Svergun, Dmitri; Cheng, R Holland; Wu, Jinhua; Hytönen, Vesa P; et al.. 2020. Journal of cell science. 133: jcs239202
Structural and functional insights into the unique CBS-CP12 fusion protein family in cyanobacteria
Hackenberg, Claudia; Hakanpää, Johanna; Cai, Fei; Antonyuk, Svetlana; Eigner, Caroline; Meissner, Sven; Laitaoja, Mikko; Jänis, Janne; Kerfeld, Cheryl A; Dittmann, Elke; Lamzin, Victor S. 2018. Proceedings of the National Academy of Sciences of the United States of America. 115: 7141-7146
Identification and characterization of a novel zebrafish (Danio rerio) pentraxin-carbonic anhydrase
Patrikainen MS, Tolvanen MEE, Aspatwar A, Barker HR, Ortutay C, Jänis J, Laitaoja M, Hytönen VP, Azizi L, Manandhar P, Jáger E, Vullo D, Kukkurainen S, Hilvo M, Supuran CT, Parkkila S. 2017. PeerJ. : e4128
Deciphering metal ion preference and primary coordination sphere robustness of a designed zinc finger with high-resolution mass spectrometry
Laitaoja Mikko, Isoniemi Sari, Valjakka Jarkko, Mándity István M, Jänis Janne. 2016. Protein science. 2017; 26: 198-207
Redox-dependent disulfide bond formation in SAP30L corepressor protein: Implications for structure and function
Laitaoja Mikko, Tossavainen Helena, Pihlajamaa Tero, Valjakka Jarkko, Viiri Keijo, Lohi Olli, Permi Perttu, Jänis Janne. 2016. Protein science. 25: 572-586
Structure-function studies of zinc proteins
Laitaoja Mikko. 2016. Dissertations. Department of Chemistry. University of Eastern Finland
Zinc coordination spheres in protein structures
Laitaoja M, Valjakka J, Jänis J. 2013. Inorganic chemistry. 52: 10983-10991
Top-down mass spectrometry reveals new sequence variants of the major bovine seminal plasma protein PDC-109
Laitaoja M, Sankhala RS, Swamy MJ, Jänis J. 2012. Journal of mass spectrometry. 47: 853-859
Bifunctional avidin with covalently modifiable ligand binding site
Leppiniemi J, Määttä JA, Hammaren H, Soikkeli M, Laitaoja M, Jänis J, Kulomaa MS, Hytönen VP. 2011. PLoS ONE. 6: e16576
Effect of Glycosylation and Additional Domains on the Thermostability of a Family 10 Xylanase Produced by Thermopolyspora flexuosa
Sasikala Anbarasan, Janne Jänis, Marja Paloheimo, Mikko Laitaoja, Minna Vuolanto, Johanna Karimäki, Pirjo Vainiotalo, Matti Leisola, and Ossi Turunen. 2010. Applied and environmental microbiology. 76: 356-360