Department of Technical Physics, Faculty of Science, Forestry and Technology
firstname.lastname@example.org | +358 50 595 5517
Dr. Nissi is an Associate Professor at the Department of Technical Physics at the University of Eastern Finland, Kuopio, Finland. Dr. Nissi leads a research group focusing on pre-clinical quantitative magnetic resonance imaging (qMRI). In 2021, Dr. Nissi also served as a deputy head of the department. The research topics in the group include relaxometry methods, such as various rotating and laboratory frame relaxation methods and imaging strategies, as well as quantitative susceptibility mapping. While the primary field of target applications for qMRI in Dr. Nissi’s group has been musculoskeletal diseases and their diagnostics, the research interests of his group concern especially methodological development of ultra-short echo time / SWIFT imaging sequences as well as image acquisition and reconstruction strategies for various target applications.
The most recent project fundings granted to Dr. Nissi concern development of AI-assisted virtual histology using magnetic resonance fingerprinting (Research Council of Finland, grant #354693), depelopment of rapid quantitative ultra-short echo time MRI methods using primarily the SWIFT sequence and its variants and iterative compressed sensing reconstruction methods (Research Council of Finland, grant #325146) and developing an innovation and development environment for industrial applications of material research using microMRI, consisting of investment of an 11.74 T microMRI device and of various pilot projects on microMRI of agricultural and industrial products (European Regional Development Fund, grants #A73998 and #A74016).
Teaching and other activities
3-D T1 relaxation time measurements in an equine model of subtle post-traumatic osteoarthritis using MB-SWIFTPala, Swetha; Hänninen, Nina E; Mohammadi, Ali; Ebrahimi, Mohammadhossein; te Moller, Nikae CR; Brommer, Harold; René van Weeren, P; Mäkelä, Janne TA; Korhonen, Rami K; Afara, Isaac O; Töyräs, Juha; Mikkonen, Santtu; Nissi, Mikko J; Nykänen, Olli. 2023. Journal of orthopaedic research. 41: 2657-2666
Assessing post-traumatic changes in cartilage using T1 dispersion parametersElsayed, Hassaan; Karjalainen, Jouni; Nissi, Mikko J.; Ketola, Juuso; Kajabi, Abdul Wahed; Casula, Victor; Zbýň, Štefan; Nieminen, Miika T.; Hanni, Matti. 2023. Magnetic resonance imaging. 97: 91-101
Axon fiber orientation as the source of T1 relaxation anisotropy in white matter: A study on corpus callosum in vivo and ex vivoKauppinen, Risto A; Thothard, Jeromy; Leskinen, Henri PP; Pisharady, Pramod K; Manninen, Eppu; Kettunen, Mikko; Lenglet, Christophe; Gröhn, Olli HJ; Garwood, Michael; Nissi, Mikko J. 2023. Magnetic resonance in medicine. 90: 708-721
Does T1ρ Measure Proteoglycan Concentration in Cartilage?Casula, Victor; Karjalainen, Jouni; Mlynarik, Vladimir; Liimatainen, Timo; Hanni, Matti; Oei, Edwin H.G.; Nissi, Mikko J.; Nieminen, Miika T.. 2023. Journal of magnetic resonance imaging. [First published: 12 September 2023]: 1-2
Fast Compressed Sensing of 3D Radial T1 Mapping with Different Sparse and Low-Rank ModelsPaajanen, Antti; Hanhela, Matti; Hänninen, Nina; Nykänen, Olli; Kolehmainen, Ville; Nissi, Mikko J. 2023. Journal of imaging. 9:
Magnetic resonance imaging of water vapor absorption in simulated corrugated boardTuomainen, Teemu V; Silvennoinen, Jukka; Mattila, Terhi; Kettunen, Mikko I; Nissi, Mikko J. 2023. Cellulose. 30: 9271-9281
T2 orientation anisotropy mapping of articular cartilage using qMRILeskinen, Henri PP; Hänninen, Nina; Nissi, Mikko J. 2023. Physics in medicine and biology. 68:
A musculoskeletal finite element model of rat knee joint for evaluating cartilage biomechanics during gaitOrozco, Gustavo A.; Karjalainen, Kalle; Moo, Eng Kuan; Stenroth, Lauri; Tanska, Petri; Rios, Jaqueline Lourdes; Tuomainen, Teemu V.; Nissi, Mikko J.; Isaksson, Hanna; Herzog, Walter; Korhonen, Rami K.. 2022. PLoS computational biology. 18:
Anisotropy of T2 and T1ρ Relaxation in Bovine Articular Cartilage at 3 TKantola, Ville; Karjalainen, Jouni; Jaakola, Tomi; Leskinen, Henri; Nissi, Mikko; Nieminen, Miika; Casula, Victor. 2022. Proceedings of the International Society for Magnetic Resonance in Medicine, Scientific Meeting and Exhibition
Compositional MRI of articular cartilage — current status and the way forwardNieminen, M.T.; Casula, V.; Nissi, M.J.. 2022. Osteoarthritis and cartilage. 30: 633-635