MINNA KAIKKONEN-MääTTä
Academy Research Fellow
Our research is focused on the fundamental mechanisms underlying coronary artery disease (CAD). We employ a wide-array of next-generation sequencing methods (GRO-Seq, TRAP-Seq, scRNA-Seq, RIBO-Seq, RNA-Seq, miRNA-Seq, Hi-C) to 1) study the contributions of different cell types in disease progression (cell types of the vessel wall, adipose tissue and liver), 2) characterize the gene regulatory mechanisms driving cell identity such as the role of non-coding RNAs and to 3) study molecular mechanisms of how CAD risk variants act by altering the activity of regulatory regions such as enhancers.
Contact info
Organization
Faculty of Health Sciences, A.I. Virtanen Institute for Molecular Sciences
minna.kaikkonen@uef.fi
Phone
+358 40 355 2413