I am senior scientist (Docent/Adjunct Professor) and an initiator of the brain tumor research line which utilizes patient material. The current interest involve malignant brain tumors, particularly glioblastoma. We are determing its characteristics and aiming for the discovery of new cancer biomarkers. In addition, we are using multiple approaches to modeling disease. I have coordinating role in the study which is working in the network manner. More detailed information of biomarkers may benefit patient diagnostics and help to select and design better and more personalized therapies in the future.
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Pahanlaatuisen gliooman hoidon tulevaisuuden näkymiä
Olsson, Venla; Niittykoski, Minna; Stedt, Hanna; Virsunen, Heli; Ylä-Herttuala, Seppo. 2020. Duodecim. 136: 1242-1248 -
The Regulation of NFE2L2 (NRF2) Signalling and Epithelial-to-Mesenchymal Transition in Age-Related Macular Degeneration Pathology
Hyttinen, JMT; Kannan, R; Felszeghy, S; Niittykoski, M; Salminen, A; Kaarniranta, K. 2019. International journal of molecular sciences. 20: 5800 -
Immunohistochemical Characterization and Sensitivity to Human Adenovirus Serotypes 3, 5, and 11p of New Cell Lines Derived from Human Diffuse Grade II to IV Gliomas
Niittykoski Minna, von und zu Fraunberg Mikael, Martikainen Miika, Rauramaa, Immonen Arto, Koponen Susanna, Leinonen Ville, Vähä-Koskela Markus, Zhang Qiwei, Kühnel Florian, Mei Ya-Fang, Ylä-Herttuala Seppo, Jääskeläinen Juha E, Hinkkanen Ari. 2017. Translational oncology. 10: 772-779 -
Attenuated Semliki Forest virus for cancer treatment in dogs: safety assessment in two laboratory Beagles
Autio Karoliina PM, Ruotsalainen Janne J, Anttila Marjukka O, Niittykoski Minna, Waris Matti, Hemminki Akseli, Vähä-Koskela Markus JV, Hinkkanen Ari E. 2015. Bmc veterinary research. 11: 170 -
MicroRNA-attenuated Clone of Virulent Semliki Forest Virus Overcomes Antiviral Type I Interferon in Resistant Mouse CT-2A Glioma
Martikainen Miika, Niittykoski Minna, von und zu Fraunberg Mikael, Immonen Arto, Koponen Susanna, van Geenen Maartje, Vähä-Koskela Markus, Ylösmäki Erkko, Jääskeläinen Juha E, Saksela Kalle, Hinkkanen Ari. 2015. Journal of virology. 89: 10637-10647 -
Clonal variation in interferon response determines the outcome of oncolytic virotherapy in mouse CT26 colon carcinoma model
Ruotsalainen JJ, Kaikkonen MU, Niittykoski M, Martikainen MW, Lemay CG, Cox J, De Silva NS, Kus A, Falls TJ, Diallo JS, Le Boeuf F, Bell JC, Ylä-Herttuala S, Hinkkanen AE, Vähä-Koskela MJ. 2014. Gene therapy. : -- -
Maturation of autophagosomes and endosomes: A key role for Rab7
Hyttinen JMT, Niittykoski M, Salminen A, Kaarniranta K. 2013. Biochimica et biophysica acta: international journal of biochemistry and biophysics. 1833: 503-510 -
The role of NMDA and mGluR5 receptors in calcium mobilization and neurotoxicity of homocysteine in trigeminal and cortical neurons and glial cells
Abushik PA, Niittykoski M, Giniatullina R, Shakirzyanova A, Bart G, Fayuk D, Sibarov DA, Antonov SM, Giniatullin R. 2013. Journal of neurochemistry. [Epub ahead of print]: x-x -
Interferon-β sensitivity of tumor cells correlates with poor response to VA7 virotherapy in mouse glioma models
Ruotsalainen J, Martikainen M, Niittykoski M, Huhtala T, Aaltonen T, Heikkilä J, Bell J, Vähä-Koskela M, Hinkkanen A. 2012. Molecular therapy. 2012 Aug;20(8): 1529-39 -
Unusually strong temperature dependence of P2X3 receptor traffic to the plasma membrane
Pryazhnikov E, Fayuk D, Niittykoski M, Giniatullin R, Khiroug L. 2011. Frontiers in cellular neuroscience. : --