Moustafa Hamada

Doctoral Researcher

Department of Technical Physics, Faculty of Science, Forestry and Technology

[email protected]

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Information Publications

My current research focus is to reveal new possible biochemically and biomechanically driven degradation mechanisms of articular cartilage at the onset of post-traumatic osteoarthritis. Through a set of tissue- and cell-level experiments, the aim is to deepen our understanding of the disease progression at the very early-phase.

Research groups

Biophysics of Bone and Cartilage (BBC) 01.01.1998 -

Keywords

biomechanics cartilage inflammation infrared spectroscopy osteoarthritis

Publications

2/2 items

Time-dependent computational model of post-traumatic osteoarthritis to estimate how mechanoinflammatory mechanisms impact cartilage aggrecan content
Eskelinen, Atte SA; Kosonen, Joonas P; Hamada, Moustafa; Esrafilian, Amir; Florea, Cristina; Grodzinsky, Alan J; Tanska, Petri; Korhonen, Rami K, 2025, PLoS computational biology, 21, 10, e1013641. A1 Journal article (refereed), original research
Loss of collagen content is localized near cartilage lesions on the day of injurious loading and intensified on day 12
Hamada, Moustafa; Eskelinen, Atte SA; Florea, Cristina; Mikkonen, Santtu; Nieminen, Petteri; Grodzinsky, Alan J; Tanska, Petri; Korhonen, Rami K, 2024, Journal of orthopaedic research, 43, 1, 70-83. A1 Journal article (refereed), original research

University of Eastern Finland Joensuu, Kuopio © University of Eastern Finland

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Moustafa Hamada

Research groups

Keywords

Time-dependent computational model of post-traumatic osteoarthritis to estimate how mechanoinflammatory mechanisms impact cartilage aggrecan content

Loss of collagen content is localized near cartilage lesions on the day of injurious loading and intensified on day 12