Niina Aaltonen - UEFConnect

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Transcription factor crosstalk in cancers - Paakinaho lab 01.01.2022 -

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Central role of SUMOylation in the regulation of chromatin interactions and transcriptional outputs of the androgen receptor in prostate cancer cells
Launonen, Kaisa-Mari; Varis, Vera; Aaltonen, Niina; Niskanen, Einari A; Varjosalo, Markku; Paakinaho, Ville; Palvimo, Jorma J. 2024. Nucleic acids research. 52: 9519-9535 A1 Journal article (refereed), original research
Development of Focused Ultrasound-Assisted Nanoplexes for RNA Delivery
Ranjan, Sanjeev; Bosch, Stef; Lukkari, Hannamari; Schirmer, Johanna; Aaltonen, Niina; Nieminen, Heikki J; Lehto, Vesa-Pekka; Urtti, Arto; Lajunen, Tatu; Rilla, Kirsi. 2024. Nanomaterials. 14: A1 Journal article (refereed), original research
EP300/CREBBP acetyltransferase inhibition limits steroid receptor and FOXA1 signaling in prostate cancer cells
Huttunen, Jasmin; Aaltonen, Niina; Helminen, Laura; Rilla, Kirsi; Paakinaho, Ville. 2024. Cellular and molecular life sciences. 81: . 160 A1 Journal article (refereed), original research
Increased secretion of adipocyte-derived extracellular vesicles is associated with adipose tissue inflammation and the mobilization of excess lipid in human obesity
Matilainen, Johanna; Berg, Viivi; Vaittinen, Maija; Impola, Ulla; Mustonen, Anne-Mari; Männistö, Ville; Malinen, Marjo; Luukkonen, Veera; Rosso, Natalia; Turunen, Tanja; Käkelä, Pirjo; Palmisano, Silvia; Arasu, Uma Thanigai; Sihvo, Sanna P.; Aaltonen, Niina; Härkönen, Kai; Caddeo, Andrea; Kaminska, Dorota; Pajukanta, Päivi; Kaikkonen, Minna U.; Tiribelli, Claudio; Käkelä, Reijo; Laitinen, Saara; Pihlajamäki, Jussi; Nieminen, Petteri; Rilla, Kirsi. 2024. Journal of translational medicine. 22: . 623 A1 Journal article (refereed), original research
Chromatin accessibility and pioneer factor FOXA1 restrict glucocorticoid receptor action in prostate cancer
Helminen, Laura; Huttunen, Jasmin; Tulonen, Melina; Aaltonen, Niina; Niskanen, Einari A; Palvimo, Jorma J; Paakinaho, Ville. 2023. Nucleic acids research. 2024; 52: 625-642 A1 Journal article (refereed), original research
M1 Macrophages Induce Protumor Inflammation in Melanoma Cells through TNFR–NF-κB Signaling
Kainulainen, Kirsi; Takabe, Piia; Heikkinen, Sami; Aaltonen, Niina; de la Motte, Carol; Rauhala, Leena; Durst, Franziska C; Oikari, Sanna; Hukkanen, Taija; Rahunen, Eija; Ikonen, Ella; Hartikainen, Jaana M; Ketola, Kirsi; Pasonen-Seppänen, Sanna. 2022. Journal of investigative dermatology. 1412: 3041-3051.e10 A1 Journal article (refereed), original research
MCF10CA Breast Cancer Cells Utilize Hyaluronan-Coated EV-Rich Trails for Coordinated Migration
Aaltonen, Niina; Kyykallio, Heikki; Tollis, Sylvain; Capra, Janne; Hartikainen, Jaana M.; Matilainen, Johanna; Oikari, Sanna; Rilla, Kirsi. 2022. Frontiers in oncology. 12: . 869417 A1 Journal article (refereed), original research
The role of FoxP3+ regulatory T cells and IDO+ immune and tumor cells in malignant melanoma - an immunohistochemical study
Salmi, Satu; Lin, Anton; Hirschovits-Gerz, Benjamin; Valkonen, Mari; Aaltonen, Niina; Sironen, Reijo; Siiskonen, Hanna; Pasonen-Seppänen, Sanna. 2021. Bmc cancer. 21: 641 A1 Journal article (refereed), original research
High-Resolution Confocal Fluorescence Imaging of Serine Hydrolase Activity in Cryosections - Application to Glioma Brain Unveils Activity Hotspots Originating from Tumor-Associated Neutrophils
Aaltonen, Niina; Singha, Prosanta; Jakupovic, Hermina; Wirth, Thomas; Samaranayake, Haritha; Pasonen-Seppänen, Sanna; Rilla, Kirsi; Varjosalo, Markku; Edgington-Mitchell, Laura; Kasperkiewicz, Paulina; Drag, Marcin; Kälvälä, Sara; Moisio, Eemeli; Savinainen, Juha; Laitinen, Jarmo. 2020. Biological procedures online. 22: 6 A1 Journal article (refereed), original research
In vivo characterization of the ultrapotent monoacylglycerol lipase inhibitor {4-[bis-(benzo[d][1,3]dioxol-5-yl)methyl]-piperidin-1-yl} (1H-1,2,4-triazol-1-yl)methanone (JJKK-048)
Aaltonen Niina, Kedzierska Ewa, Orzelska-Gorka Jolanta, Lehtonen Marko, Navia-Paldanius Dina, Jakupovic Hermina, Savinainen Juha, Nevalainen Tapio, Laitinen Jarmo T, Parkkari Teija, Gynther Mikko. 2016. Journal of pharmacology and experimental therapeutics. 359: 62-72 A1 Journal article (refereed), original research
Increased tonic cannabinoid CB1R activity and brain region-specific desensitization of CB1R Gi/o signaling axis in mice with global genetic knockout of monoacylglycerol lipase
Navia-Paldanius Dina, Aaltonen Niina, Lehtonen Marko, Savinainen Juha R, Taschler Ulrike, Radner Franz PW, Zimmermann Robert, Laitinen Jarmo T. 2015. European journal of pharmaceutical sciences. 77: 180-188 A1 Journal article (refereed), original research
Optimization of 1,2,5-thiadiazole carbamates as potent and selective ABHD6 inhibitors
Patel Jayendra Z, Nevalainen Tapio J, Savinainen Juha R, Adams Yahaya, Laitinen Tuomo, Runyon Robert S, Vaara Miia, Ahenkorah Stephen, Kaczor Agnieszka A, Navia-Paldanius Dina, Gynther Mikko, Aaltonen Niina, Joharapurkar Amit A, Jain Mukul R, Haka Abigail S, Maxfield Frederick R, Laitinen Jarmo T, Parkkari Teija. 2014. Chemmedchem. 2015; 10: 253-265 A1 Journal article (refereed), original research
Brain regional cannabinoid CB1 receptor signalling and alternative enzymatic pathways for 2-arachidonoylglycerol generation in brain sections of diacylglycerol lipase deficient mice
Aaltonen Niina, Ribas Casandra R, Lehtonen Marko, Savinainen Juha R, Laitinen Jarmo T. 2013. European journal of pharmaceutical sciences. 2014:51: 87-95 A1 Journal article (refereed), original research
Piperazine and piperidine triazole ureas as ultrapotent and highly selective inhibitors of monoacylglycerol lipase
Aaltonen Niina, Savinainen Juha R, Ribas Casandra R, Rönkkö Jani, Kuusisto Anne, Korhonen Jani, Navia-Paldanius Dina, Häyrinen Jukka, Takabe Piia, Käsnänen Heikki, Pantsar Tatu, Laitinen Tuomo, Lehtonen Marko, Pasonen-Seppänen Sanna, Poso Antti, Nevalainen Tapio, Laitinen Jarmo T. 2013. Chemistry and biology. 20: 379-390 A1 Journal article (refereed), original research
Quantification of endocannabinoids in postmortem brain of schizophrenic subjects
Muguruza Carolina, Lehtonen Marko, Aaltonen Niina, Morentin Benito, Meana J. Javier, Callado Luis F. 2013. Schizophrenia research. 148: 145-150 A1 Journal article (refereed), original research
Lipid phosphate phosphatase inhibitors locally amplify lysophosphatidic acid LPA1 receptor signalling in rat brain cryosections without affecting global LPA degradation
Aaltonen Niina, Lehtonen Marko, Varonen Katri, Goterris Gemma Arrufat, Laitinen Jarmo T. 2012. Bmc pharmacology. 12: 7 A1 Journal article (refereed), original research
Quantification of lysophosphatidic acids in rat brain tissue by liquid chromatography-electrospray tandem mass spectrometry
Aaltonen N, Laitinen JT & Lehtonen M. 2010. Journal of chromatography b: analytical technologies in the biomedical and life sciences. 878: 1145 - 1152 A1 Journal article (refereed), original research
Neuroanatomical mapping of juvenile rat brain regions with prominent basal signal in [35S]GTPgammaS autoradiography
Aaltonen N, Palomäki VAB, Lecklin A, Laitinen JT. 2008. Journal of chemical neuroanatomy. 35: 233-241 A1 Journal article (refereed), original research