Petra Mäkinen

A Small TAT-TrkB Peptide Prevents BDNF Receptor Cleavage and Restores Synaptic Physiology in Alzheimer’s Disease

Fonseca-Gomes, João; Costa-Coelho, Tiago; Ferreira-Manso, Mafalda; Inteiro-Oliveira, Sara; Vaz, Sandra H; Alemãn-Serrano, Nuno; Atalaia-Barbacena, Henrique; Ribeiro-Rodrigues, Leonor; Ramalho, Rita M; Pinto, Rui; Miranda, Hugo Vicente; Tanqueiro, Sara R; de Almeida-Borlido, Carolina; Ramalho, Maria João; Miranda-Lourenço, Catarina; Belo, Rita F; Ferreira, Catarina B; Neves, Vera; Rombo, Diogo M; Viais, Ricardo; Martins, Ivo C; Jerónimo-Santos, André; Caetano, António; Manso, Nuno; Mäkinen, Petra. 2024. Molecular therapy. 32: 3372-3401 A1 Journal article (refereed), original research

Organotypic Hippocampal Slice Cultures from Adult Tauopathy Mice and Theragnostic Evaluation of Nanomaterial Phospho-TAU Antibody-Conjugates

Kemppainen, Susanna; Huber, Nadine; Willman, Roosa-Maria; Zamora, Ana; Makinen, Petra; Martiskainen, Henna; Takalo, Mari; Haapasalo, Annakaisa; Sobrino, Tomas; Gomez, Manuel Antonio Gonzalez; Pineiro, Yolanda; Rivas, Jose; Himmelreich, Uwe; Hiltunen, Mikko. 2023. Cells. 12: A1 Journal article (refereed), original research

Protective Alzheimer's disease-associated APP A673T variant predominantly decreases sAPPβ levels in cerebrospinal fluid and 2D/3D cell culture models

Wittrahm, Rebekka; Takalo, Mari; Kuulasmaa, Teemu; Mäkinen, Petra M; Mäkinen, Petri; Končarević, Saša; Fartzdinov, Vadim; Selzer, Stefan; Kokkola, Tarja; Antikainen, Leila; Martiskainen, Henna; Kemppainen, Susanna; Marttinen, Mikael; Jeskanen, Heli; Rostalski, Hannah; Rahunen, Eija; Kivipelto, Miia; Ngandu, Tiia; Natunen, Teemu; Lambert, Jean-Charles; Tanzi, Rudolph E; Kim, Doo Yeon; Rauramaa, Tuomas; Herukka, Sanna-Kaisa; Soininen, Hilkka; Laakso, Markku; Pike, Ian; Leinonen, Ville; Haapasalo, . 2023. Neurobiology of disease. 182: A1 Journal article (refereed), original research

Elevated CSF LRG and Decreased Alzheimer's Disease Biomarkers in Idiopathic Normal Pressure Hydrocephalus

Vanninen, Aleksi; Nakajima, Madoka; Miyajima, Masakazu; Rauramaa, Tuomas; Kokki, Merja; Musialowicz, Tadeusz; Mäkinen, Petra M; Herukka, Sanna-Kaisa; Koivisto, Anne M; Jääskeläinen, Juha E; Hiltunen, Mikko; Leinonen, Ville. 2021. Journal of clinical medicine. 10: 1105 A1 Journal article (refereed), original research

Hyvät pahat mikrogliat Alzheimerin taudissa

Mäkinen, Petra; Holappa-Girginkaya, Jaana. 2021. BIOANALYYTIKKO. 4: 37-39 D1 Article in a trade journal

Isoflurane affects brain functional connectivity in rats 1 month after exposure

Stenroos, Petteri; Pirttimäki, Tiina; Paasonen, Jaakko; Paasonen, Ekaterina; Salo, Raimo A; Koivisto, Hennariikka; Natunen, Teemu; Mäkinen, Petra; Kuulasmaa, Teemu; Hiltunen, Mikko; Tanila, Heikki; Gröhn, Olli. 2021. Neuroimage. 234: 117987 A1 Journal article (refereed), original research

MECP2 Increases the Pro-Inflammatory Response of Microglial Cells and Phosphorylation at Serine 423 Regulates Neuronal Gene Expression upon Neuroinflammation

Wittrahm, Rebekka; Takalo, Mari; Marttinen, Mikael; Kuulasmaa, Teemu; Mäkinen, Petra; Kemppainen, Susanna; Martiskainen, Henna; Rauramaa, Tuomas; Pike, Ian; Leinonen, Ville; Natunen, Teemu; Haapasalo, Annakaisa; Hiltunen, Mikko. 2021. Cells. 10: 860 A1 Journal article (refereed), original research

S327 phosphorylation of the presynaptic protein SEPTIN5 increases in the early stages of neurofibrillary pathology and alters the functionality of SEPTIN5

Ferreira, Catarina B.; Marttinen, Mikael; Coelho, Joana E.; Paldanius, Kaisa M.A.; Takalo, Mari; Mäkinen, Petra; Leppänen, Luukas; Miranda-Lourenço, Catarina; Fonseca-Gomes, João; Tanqueiro, Sara R.; Vaz, Sandra H.; Belo, Rita F.; Sebastião, Ana Maria; Leinonen, Ville; Soininen, Hilkka; Pike, Ian; Haapasalo, Annakaisa; Lopes, Luísa V.; de Mendonça, Alexandre; Diógenes, Maria José; Hiltunen, Mikko. 2021. Neurobiology of disease. 2022; 163: 105603 A1 Journal article (refereed), original research

BV-2 Microglial Cells Overexpressing C9orf72 Hexanucleotide Repeat Expansion Produce DPR Proteins and Show Normal Functionality but No RNA Foci

Rostalski, Hannah; Hietanen, Tomi; Leskelä, Stina; Behánová, Andrea; Abdollahzadeh, Ali; Wittrahm, Rebekka; Mäkinen, Petra; Huber, Nadine; Hoffmann, Dorit; Solje, Eino; Remes, Anne M; Natunen, Teemu; Takalo, Mari; Tohka, Jussi; Hiltunen, Mikko; Haapasalo, Annakaisa. 2020. Frontiers in neurology. 11: 550140 A1 Journal article (refereed), original research

Diabetic phenotype in mouse and humans reduces the number of microglia around ß-amyloid plaques

Natunen, Teemu; Martiskainen, Henna; Marttinen, Mikael; Gabbouj, Sami; Koivisto, Hennariikka; Kemppainen, Susanna; Kaipainen, Satu; Takalo, Mari; Svobodová, Helena; Leppänen, Luukas; Kemiläinen, Benjam; Ryhänen, Simo; Kuulasmaa, Teemu: Rahunen, Eija: Juutinen, Sisko; Mäkinen, Petra; Miettinen, Pasi; Rauramaa, Tuomas; Pihlajamäki, Jussi; Haapasalo, Annakaisa; et al [incl. Leinonen, Ville; Tanila, Heikki; Hiltunen, Mikko]. 2020. Molecular neurodegeneration. 15: 66 A1 Journal article (refereed), original research

PTPR type Q in cerebrospinal fluid reflects ependymal cells dysfunction and is a potential biomarker for adult chronic hydrocephalus

Nakajima, Madoka; Rauramaa, Tuomas; Mäkinen, Petra M; Hiltunen, Mikko; Herukka, Sanna-Kaisa; Kokki, Merja; Musialowicz, Tadeusz; Jyrkkänen, Henna-Kaisa; Danner, Nils; Junkkari, Antti; Koivisto, Anne M; Jääskeläinen, Juha E; Miyajima, Masakazu; Ogino, Ikuko; Furuta, Akiko; Akiba, Chihiro; Kawamura, Kaito; Kamohara, Chihiro; Sugano, Hidenori; Tange, Yuichi; et al. [incl. Leinonen, Ville]. 2020. European journal of neurology. 2021; 28: 389-400 A1 Journal article (refereed), original research

Presynaptic Vesicle Protein SEPTIN5 Regulates the Degradation of APP C-Terminal Fragments and the Levels of Aß

Marttinen, Mikael; Ferreira, Catarina B; Paldanius, Kaisa M A; Takalo, Mari; Natunen, Teemu; Mäkinen, Petra; Leppänen, Luukas; Leinonen, Ville; Tanigaki, Kenji; Kang, Gina; Hiroi, Noboru; Soininen, Hilkka; Rilla, Kirsi; Haapasalo, Annakaisa; Hiltunen, Mikko. 2020. Cells. 9: 2482 A1 Journal article (refereed), original research

The Alzheimer's disease-associated protective Plcγ2-P522R variant promotes immune functions

Takalo, Mari; Wittrahm, Rebekka; Wefers, Benedikt; Parhizkar, Samira; Jokivarsi, Kimmo; Kuulasmaa, Teemu; Mäkinen, Petra; Martiskainen, Henna; Wurst, Wolfgang; Xiang, Xianyuan; Marttinen, Mikael; Poutiainen, Pekka; Haapasalo, Annakaisa; Hiltunen, Mikko; Haass, Christian. 2020. Molecular neurodegeneration. 15: 52 A1 Journal article (refereed), original research

BIN1 recovers tauopathy-induced long-term memory deficits in mice and interacts with Tau through Thr348 phosphorylation

Sartori, M; Mendes, T; Desai, S; Lasorsa, A; Herledan, A; Malmanche, N; Mäkinen, P; Marttinen, M; Malki, I; Chapuis, J; Flaig, A; Vreulx, AC; Ciancia, M; Amouyel, P; Leroux, F; Déprez, B; Cantrelle, FX; Maréchal, D; Pradier, L; Hiltunen, M; et al.. 2019. Acta neuropathologica. 138: 631-652 A1 Journal article (refereed), original research

A multiomic approach to characterize the temporal sequence in Alzheimer's disease-related pathology

Marttinen, M; Paananen, J; Neme, A; Mitra, V; Takalo, M; Natunen, T; Paldanius, KMA; Mäkinen, P; Bremang, M; Kurki, MI; Rauramaa, T; Leinonen, V; Soininen, H; Haapasalo, A; Pike, I; Hiltunen, M. 2018. Neurobiology of disease. 2019; 124: 454-468 A1 Journal article (refereed), original research

Interrelationship between the Levels of C9orf72 and Amyloid-ß Protein Precursor and Amyloid-ß in Human Cells and Brain Samples

Leskelä, S; Takalo, M; Marttinen, M; Huber, N; Paananen, J; Mitra, V; Rauramaa, T; Mäkinen, P; Leinonen, V; Soininen, H; Pike, I; Remes, AM; Hiltunen, M; Haapasalo, A. 2018. Journal of Alzheimer's disease. 62: 269-278 A1 Journal article (refereed), original research

Intranasal insulin activates Akt2 signaling pathway in the hippocampus of wild-type but not in APP/PS1 Alzheimer model mice

Gabbouj, S; Natunen, T; Koivisto, H; Jokivarsi, K; Takalo, M; Marttinen, M; Wittrahm, R; Kemppainen, S; Naderi, R; Posado-Fernández, A; Ryhänen, S; Mäkinen, P; Paldanius, KMA; Doria, G; Poutiainen, P; Flores, O; Haapasalo, A; Tanila, H; Hiltunen, M. 2018. Neurobiology of aging. 2019; 75: 98-108 A1 Journal article (refereed), original research

Protein kinase C -activating isophthalate derivatives mitigate Alzheimer's disease-related cellular alterations

Sarajärvi, T; Jäntti, M; Paldanius, KMA; Natunen, T; Wu, JC; Mäkinen, P; Tarvainen, I; Tuominen, RK; Talman, V; Hiltunen, M. 2018. Neuropharmacology. 141: 76-88 A1 Journal article (refereed), original research

DHCR24 exerts neuroprotection upon inflammation-induced neuronal death

Martiskainen H, Paldanius KMA, Natunen T, Takalo M, Marttinen M, Leskelä S, Huber N, Mäkinen P, Bertling E, Dhungana H, Huuskonen M, Honkakoski P, Hotulainen P, Rilla K, Koistinaho J, Soininen H, Malm T, Haapasalo A, Hiltunen M. 2017. Journal of neuroinflammation. : 215 A1 Journal article (refereed), original research

SEPT8 modulates ß-amyloidogenic processing of APP by affecting the sorting and accumulation of BACE1

Kurkinen Kaisa MA, Marttinen Mikael, Turner Laura, Natunen Teemu, Mäkinen Petra, Haapalinna Fanni, Sarajärvi Timo, Gabbouj Sami, Kurki Mitja, Paananen Jussi, Koivisto Anne M, Rauramaa Tuomas, Leinonen Ville, Tanila Hanila, Soininen Hilkka, Lucas Fiona R, Haapasalo Annakaisa, Hiltunen Mikko. 2016. Journal of cell science. 129: 2224-2238 A1 Journal article (refereed), original research

Effects of Alzheimer's Disease-Associated Risk Loci on Cerebrospinal Fluid Biomarkers and Disease Progression: A Polygenic Risk Score Approach

Martiskainen Henna, Helisalmi Seppo, Viswanathan Jayashree, Kurki Mitja, Hall Anette, Herukka Sanna-Kaisa, Sarajärvi Timo, Natunen Teemu, Kurkinen Kaisa M.A., Huovinen Jaakko, Mäkinen Petra, Laitinen Marjo, Koivisto Anne M., Mattila Kari M., Lehtimäki Terho, Remes Anne M., Leinonen Ville, Haapasalo Annakaisa, Soininen Hilkka, Hiltunen Mikko. 2015. Journal of Alzheimer's disease. 43: 565-573 A1 Journal article (refereed), original research

Genetic Variation in delta-Opioid Receptor Associates with Increased ß- and gamma-Secretase Activity in the Late Stages of Alzheimer's Disease

Sarajärvi Timo, Marttinen Mikael, Natunen Teemu, Kauppinen Tarja, Mäkinen Petra, Helisalmi Seppo, Laitinen Marjo, Rauramaa Tuomas, Leinonen Ville, Petäjä-Repo Ulla, Soininen Hilkka, Haapasalo Annakaisa, Hiltunen Mikko. 2015. Journal of Alzheimer's disease. 48: 507-516 A1 Journal article (refereed), original research

Relationship between ubiquilin-1 and BACE1 in human Alzheimer's disease and APdE9 transgenic mouse brain and cell-based models

Natunen Teemu, Takalo Mari, Kemppainen Ssusanna, Leskelä Stina, Marttinen Mikael, Kurkinen Kaisa MA, Pursiheimo Juha-Pekka, Sarajärvi Timo, Viswanathan Jayashree, Gabbouj Sami, Solje Eino, Tahvanainen Eveliina, Pirttimäki Tiina, Kurki Mitja, Paananen Jussi, Rauramaa Tuomas, Miettinen Pasi, Mäkinen Petra, Leinonen Ville, Soininen Hilkka et al. 2015. Neurobiology of disease. 2016; 85: 187-205 A1 Journal article (refereed), original research

High-fat diet increases tau expression in the brain of T2DM and AD mice independently of peripheral metabolic status

Takalo M, Haapasalo A, Martiskainen H, Kurkinen KM, Koivisto H, Miettinen P, Khandelwal VK, Kemppainen S, Kaminska D, Mäkinen P, Leinonen V, Pihlajamäki J, Soininen H, Laakso M, Tanila H, Hiltunen M. 2014. Journal of nutritional biochemistry. 25: 634-641 A1 Journal article (refereed), original research

KB-R7943, an inhibitor of the reverse Na(+)/Ca(2+) exchanger, does not modify secondary pathology in the thalamus following focal cerebral stroke in rats

Lipsanen Anu, Parkkinen Saara, Khabbal Joonas, Mäkinen Petra, Peräniemi Sirpa, Hiltunen Mikko, Jolkkonen Jukka. 2014. Neuroscience letters. 580: 173-177 A1 Journal article (refereed), original research

Effects of NR1H3 genetic variation on the expression of liver X receptor alfa and the progression of Alzheimer's Disease

Natunen Teemu, Martiskainen Henna, Sarajärvi Timo, Helisalmi Seppo, Pursiheimo Juha-Pekka, Viswanathan Jayashree, Laitinen Marjo, Kauppinen Tarja, Rauramaa Tuomas, Leinonen Ville, Alafuzoff Irina, Haapasalo Annakaisa, Soininen Hilkka, Hiltunen Mikko. 2013. PLoS ONE. 8: e80700 A1 Journal article (refereed), original research

Elucidation of the BACE1 regulating factor GGA3 in Alzheimer's Disease

Natunen T, Parrado AR, Helisalmi S, Pursiheimo J-P, Sarajärvi T, Mäkinen P, Kurkinen KMA, Mullin K, Alafuzoff I, Haapasalo A, Bertram L, Soininen H, Tanzi RE, Hiltunen M. 2013. Journal of Alzheimer's disease. 37: 217-232 A1 Journal article (refereed), original research

Ubiquilin-1 modulates gamma-secretase-mediated epsilon-site cleavage in neuronal cells

Viswanathan J, Haapasalo A, Kurkinen KMA, Natunen T, Mäkinen P, Bertram L, Soininen H, Tanzi RE, Hiltunen M. 2013. Biochemistry. 52: 3899-3912 A1 Journal article (refereed), original research

Anthocyanin-enriched bilberry and blackcurrant extracts modulate amyloid precursor protein processing and alleviate behavioral abnormalities in the APP/PS1 mouse model of Alzheimer's disease

Vepsäläinen Saila, Koivisto Henna, Pekkarinen Elina, Mäkinen Petra, Dobson Gary, McDougall Gordon J, Stewart Derek, Haapasalo Annakaisa, Karjalainen Reijo O, Tanila Heikki, Hiltunen Mikko. 2012. Journal of nutritional biochemistry. 24: 360-370 A1 Journal article (refereed), original research

Bepridil decreases A&#946 and calcium levels in the thalamus after middle cerebral artery occlusion in rats

Sarajärvi Timo, Lipsanen Anu, Mäkinen Petra, Peräniemi Sirpa, Soininen Hilkka, Haapasalo Annakaisa, Jolkkonen Jukka, Hiltunen Mikko. 2012. Journal of cellular and molecular medicine. 16: 2754-2767 A1 Journal article (refereed), original research

Contribution of genetic and dietary insulin resistance to Alzheimer phenotype in APP/PS1 transgenic mice

Hiltunen M, Khandelwal VKM, Yaluri N, Tiilikainen T, Tusa M, Koivisto H, Krzisch M, Vepsäläinen S, Mäkinen P, Kemppainen S, Miettinen P, Haapasalo A, Soininen H, Laakso M, Tanila H. 2012. Journal of cellular and molecular medicine. 16: 1206-1222 A1 Journal article (refereed), original research

Genetic analysis of genes involved in amyloid-beta degradation and clearance in Alzheimer's Disease

Natunen T, Helisalmi S, Vepsäläinen S, Sarajärvi T, Antikainen L, Mäkinen P, Herukka S-K, Koivisto AM, Haapasalo A, Soininen H, Hiltunen M. 2012. Journal of Alzheimer's disease. 28: 553-559 A1 Journal article (refereed), original research

Cysteine 27 variant of the delta-opioid receptor affects amyloid precursor protein processing through altered endocytic trafficking

Sarajärvi Timo, Tuusa Jussi T, Haapasalo Annakaisa, Lackman Jarkko T, Sormunen Raija, Helisalmi Seppo, Roehr Johannes T, Parrado Antonio R, Mäkinen Petra, Bertram Lars, Soininen Hilkka, Tanzi Rudolph E, Petäjä-Repo Ulla E, Hiltunen Mikko. 2011. Molecular and cellular biology. 31: 2326-2340 A1 Journal article (refereed), original research

No association between high temperature requirement 1 (HTRA1) gene polymorphisms and Alzheimer's disease

Turunen Mari, Vepsäläinen Saila, Mäkinen Petra, Helisalmi Seppo, Haapasalo Annakaisa, Soininen Hilkka, Hiltunen Mikko. 2011. Neurobiology of aging. 32: 547.e7-547.e9 A1 Journal article (refereed), original research

An association study of 21 potential Alzheimer's disease risk genes in a Finnish population

Sarajärvi T, Helisalmi S, Antikainen L, Mäkinen P, Koivisto AM, Herukka SK, Haapasalo A, Soininen H, Hiltunen M. 2010. Journal of Alzheimer's disease. 21: 763-767 A1 Journal article (refereed), original research

An association study between granulin gene polymorphisms and Alzheimer's disease in Finnish population

Viswanathan J, Mäkinen P, Helisalmi S, Haapasalo A, Soininen H, Hiltunen M, Soininen H, Hiltunen M, Helisalmi S. 2009. American journal of medical genetics. Part B : neuropsychiatric genetics. 150B: 747-750 A1 Journal article (refereed), original research

Down-regulation of seladin-1 increases BACE1 levels and activity through enhanced GGA3 depletion during apoptosis

Sarajärvi T, Haapasalo A, Viswanathan J, Mäkinen P, Laitinen M, Soininen H, Hiltunen M, Soininen H, Hiltunen M. 2009. Journal of biological chemistry. 284: 34433-34443 A1 Journal article (refereed), original research

Focal cerebral ischemia in rats alters APP processing and expression of Abeta peptide degrading enzymes in the thalamus

Hiltunen M, Mäkinen P, Peräniemi S, Sivenius J, van Groen T, Soininen H, Jolkkonen J, Hiltunen M, Sivenius J, Soininen H. 2009. Neurobiology of disease. 35: 103-113 A1 Journal article (refereed), original research

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A Small TAT-TrkB Peptide Prevents BDNF Receptor Cleavage and Restores Synaptic Physiology in Alzheimer’s Disease

Organotypic Hippocampal Slice Cultures from Adult Tauopathy Mice and Theragnostic Evaluation of Nanomaterial Phospho-TAU Antibody-Conjugates

Protective Alzheimer's disease-associated APP A673T variant predominantly decreases sAPPβ levels in cerebrospinal fluid and 2D/3D cell culture models

Elevated CSF LRG and Decreased Alzheimer's Disease Biomarkers in Idiopathic Normal Pressure Hydrocephalus

Hyvät pahat mikrogliat Alzheimerin taudissa

Isoflurane affects brain functional connectivity in rats 1 month after exposure

MECP2 Increases the Pro-Inflammatory Response of Microglial Cells and Phosphorylation at Serine 423 Regulates Neuronal Gene Expression upon Neuroinflammation

S327 phosphorylation of the presynaptic protein SEPTIN5 increases in the early stages of neurofibrillary pathology and alters the functionality of SEPTIN5

BV-2 Microglial Cells Overexpressing C9orf72 Hexanucleotide Repeat Expansion Produce DPR Proteins and Show Normal Functionality but No RNA Foci

Diabetic phenotype in mouse and humans reduces the number of microglia around ß-amyloid plaques

PTPR type Q in cerebrospinal fluid reflects ependymal cells dysfunction and is a potential biomarker for adult chronic hydrocephalus

Presynaptic Vesicle Protein SEPTIN5 Regulates the Degradation of APP C-Terminal Fragments and the Levels of Aß

The Alzheimer's disease-associated protective Plcγ2-P522R variant promotes immune functions

BIN1 recovers tauopathy-induced long-term memory deficits in mice and interacts with Tau through Thr348 phosphorylation

A multiomic approach to characterize the temporal sequence in Alzheimer's disease-related pathology

Interrelationship between the Levels of C9orf72 and Amyloid-ß Protein Precursor and Amyloid-ß in Human Cells and Brain Samples

Intranasal insulin activates Akt2 signaling pathway in the hippocampus of wild-type but not in APP/PS1 Alzheimer model mice

Protein kinase C -activating isophthalate derivatives mitigate Alzheimer's disease-related cellular alterations

DHCR24 exerts neuroprotection upon inflammation-induced neuronal death

SEPT8 modulates ß-amyloidogenic processing of APP by affecting the sorting and accumulation of BACE1

Effects of Alzheimer's Disease-Associated Risk Loci on Cerebrospinal Fluid Biomarkers and Disease Progression: A Polygenic Risk Score Approach

Genetic Variation in delta-Opioid Receptor Associates with Increased ß- and gamma-Secretase Activity in the Late Stages of Alzheimer's Disease

Relationship between ubiquilin-1 and BACE1 in human Alzheimer's disease and APdE9 transgenic mouse brain and cell-based models

High-fat diet increases tau expression in the brain of T2DM and AD mice independently of peripheral metabolic status

KB-R7943, an inhibitor of the reverse Na(+)/Ca(2+) exchanger, does not modify secondary pathology in the thalamus following focal cerebral stroke in rats

Effects of NR1H3 genetic variation on the expression of liver X receptor alfa and the progression of Alzheimer's Disease

Elucidation of the BACE1 regulating factor GGA3 in Alzheimer's Disease

Ubiquilin-1 modulates gamma-secretase-mediated epsilon-site cleavage in neuronal cells

Anthocyanin-enriched bilberry and blackcurrant extracts modulate amyloid precursor protein processing and alleviate behavioral abnormalities in the APP/PS1 mouse model of Alzheimer's disease

Bepridil decreases A&#946 and calcium levels in the thalamus after middle cerebral artery occlusion in rats

Contribution of genetic and dietary insulin resistance to Alzheimer phenotype in APP/PS1 transgenic mice

Genetic analysis of genes involved in amyloid-beta degradation and clearance in Alzheimer's Disease

Cysteine 27 variant of the delta-opioid receptor affects amyloid precursor protein processing through altered endocytic trafficking

No association between high temperature requirement 1 (HTRA1) gene polymorphisms and Alzheimer's disease

An association study of 21 potential Alzheimer's disease risk genes in a Finnish population

An association study between granulin gene polymorphisms and Alzheimer's disease in Finnish population

Down-regulation of seladin-1 increases BACE1 levels and activity through enhanced GGA3 depletion during apoptosis

Focal cerebral ischemia in rats alters APP processing and expression of Abeta peptide degrading enzymes in the thalamus