Raimo Voutilainen
Professor, Emeritus
Institute of Clinical Medicine, School of Medicine, Faculty of Health Sciences
raimo.voutilainen@uef.fi
Research groups
Publications
170/170 items-
Accelerated early childhood growth associates with the development of earlier adrenarche and puberty
Liimatta, Jani; Jääskeläinen, Jarmo; Mäntyselkä, Aino; Häkkinen, Merja R; Auriola, Seppo; Voutilainen, Raimo; Flück, Christa E; Lakka, Timo A. 2024. Journal of the Endocrine Society. 8: . bvae026 -
Health-Related Quality of Life of Young Adult Women with a History of Premature Adrenarche
Tennilä, Jussi; Sintonen, Harri; Utriainen, Pauliina; Voutilainen, Raimo; Jääskeläinen, Jarmo; Liimatta, Jani. 2024. Hormone research in paediatrics. [Epub ahead of print March 12 2024]: 1-5 -
Maternal caffeine intake during pregnancy and the risk of delivering a small for gestational age baby: Kuopio Birth Cohort
Kukkonen, Anni; Hantunen, Sari; Voutilainen, Ari; Ruusunen, Anu; Backman, Katri; Kirjavainen, Pirkka V.; Ylilauri, Maija; Voutilainen, Raimo; Pasanen, Markku; Keski-Nisula, Leea. 2024. Archives of gynecology and obstetrics. [Epub ahead of print 20 May 2024]: 1-10 -
Maternal caffeine, coffee and cola drink intake and the risk of gestational diabetes – Kuopio Birth Cohort
Kukkonen, Anni; Hantunen, Sari; Voutilainen, Ari; Ruusunen, Anu; Uusitalo, Lauri; Backman, Katri; Voutilainen, Raimo; Pasanen, Markku; Kirjavainen, Pirkka V; Keski-Nisula, Leea. 2024. Primary care diabetes. 18: 362-367 -
Quantification of urinary gonadotropins by specific assays may improve the evaluation of sex-specific hormonal changes in early infancy
Demir, And; Voutilainen, Raimo; Hero, Matti. 2024. Clinical endocrinology. [Epub ahead of print 25 April 2024]: 1-7 -
Cardiorespiratory Fitness in Young Adult Women With a History of Premature Adrenarche
Tennilä, Jussi; Jääskeläinen, Jarmo; Utriainen, Pauliina; Voutilainen, Raimo; Laitinen, Tomi; Liimatta, Jani. 2023. Journal of the Endocrine Society. 7: 1-8 -
Comparative steroid profiling of newborn hair and umbilical cord serum highlights the role of fetal adrenals, placenta, and pregnancy outcomes in fetal steroid metabolism
Koskivuori, Johanna; Voutilainen, Raimo; Storvik, Markus; Hakkinen, Merja R.; Uusitalo, Lauri; Keski-Nisula, Leea; Backman, Katri; Auriola, Seppo; Lehtonen, Marko. 2023. Journal of steroid biochemistry and molecular biology. 232: -
Effects of 2-Year Physical Activity and Dietary Intervention on Adrenarchal and Pubertal Development: The PANIC Study
Liimatta, Jani; Flück, Christa E; Mäntyselkä, Aino; Häkkinen, Merja R; Auriola, Seppo; Voutilainen, Raimo; Jääskelainen, Jarmo; Lakka, Timo A. 2023. Journal of clinical endocrinology and metabolism. 108: e1603-e1613 -
A quantitative ultra-performance liquid chromatography high-resolution mass spectrometry analysis of steroids from human scalp hair
Koskivuori, Johanna; Voutilainen, Raimo; Uusitalo, Lauri; Lehtonen, Marko; Lakka, Timo; Auriola, Seppo; Häkkinen, Merja R. 2022. Journal of pharmaceutical and biomedical analysis. 215: -
Circulating Liver-enriched Antimicrobial Peptide-2 Decreases During Male Puberty
Varimo, Tero; Miettinen, Päivi J; Vaaralahti, Kirsi; Toppari, Jorma; Huopio, Hanna; Voutilainen, Raimo; Tenhola, Sirpa; Hero, Matti; Raivio, Taneli. 2022. Journal of the Endocrine Society. 6: . bvac013 -
Health-related quality of life in boys with constitutional delay of growth and puberty
Kariola, Laura; Varimo, Tero; Huopio, Hanna; Tenhola, Sirpa; Voutilainen, Raimo; Kosola, Silja; Toppari, Jorma; Sintonen, Harri; Miettinen, Päivi J; Raivio, Taneli; Hero, Matti. 2022. Frontiers in endocrinology. 13: . 1028828 -
The Mediating Role of Endocrine Factors in the Positive Relationship Between Fat Mass and Bone Mineral Content in Children Aged 9–11 Years: The Physical Activity and Nutrition in Children Study
Constable, Annie M.; Vlachopoulos, Dimitris; Barker, Alan R.; Moore, Sarah A.; Soininen, Sonja; Haapala, Eero A.; Väistö, Juuso; Jääskeläinen, Jarmo; Voutilainen, Raimo; Auriola, Seppo; Häkkinen, Merja R.; Laitinen, Tomi; Lakka, Timo A.. 2022. Frontiers in endocrinology. 13: . 850448 -
Bone structure assessed with pQCT in prepubertal males with delayed puberty or congenital hypogonadotropic hypogonadism
Varimo, Tero; Miettinen, Päivi J; Laine, Tiina; Salonen, Pia; Tenhola, Sirpa; Voutilainen, Raimo; Huopio, Hanna; Hero, Matti; Raivio, Taneli. 2021. Clinical endocrinology. 95: 107-116 -
Boys but Not Girls Exposed to Maternal Gestational Diabetes Mellitus Have Unfavorable Fat Distribution
Antikainen, Leena; Jääskeläinen, Jarmo; Nordman, Henrikki; Voutilainen, Raimo; Huopio, Hanna. 2021. Hormone research in paediatrics. 94: 194-200 -
Diagnosis and management of primary amenorrhea and female delayed puberty
Seppä, Satu; Kuiri-Hänninen, Tanja; Holopainen, Elina; Voutilainen, Raimo. 2021. European journal of endocrinology. 184: R225-R242 -
Optical coherence tomography shows decreased thickness of retinal nerve fibre layer among foetal alcohol exposed young adults in a case-control study
Lehikoinen, Anni; Sorri, Iiris; Voutilainen, Raimo; Heinonen, Seppo. 2021. Acta ophthalmologica. 99: e1243-e1244 -
PCOS Features and Steroid Profiles Among Young Adult Women with a History of Premature Adrenarche
Tennilä, Jussi; Jääskeläinen, Jarmo; Utriainen, Pauliina; Voutilainen, Raimo; Häkkinen, Merja; Auriola, Seppo; Morin-Papunen, Laure; Liimatta, Jani. 2021. Journal of clinical endocrinology and metabolism. 106: e3335-e3345 -
Serum testosterone and oestradiol predict the growth response during puberty promoting treatment
Huttunen, Heta; Varimo, Tero; Huopio, Hanna; Voutilainen, Raimo; Tenhola, Sirpa; Miettinen, Päivi J.; Raivio, Taneli; Hero, Matti. 2021. Clinical endocrinology. 2022; 96: 220-226 -
The impact of postpartum depressive symptoms on self-reported infant health and analgesic consumption at the age of 12 months: A prospective cohort study
Ruohomäki, Aleksi; Toffol, Elena; Airaksinen, Ville; Backman, Katri; Voutilainen, Raimo; Hantunen, Sari; Tuomainen, Tomi-Pekka; Lampi, Jussi; Kokki, Hannu; Luoma, Ilona; Kumpulainen, Kirsti; Heinonen, Seppo; Keski-Nisula, Leea; Pekkanen, Juha; Pasanen, Markku; Lehto, Soili M.. 2021. Journal of psychiatric research. 136: 388-397 -
Anti-Müllerian hormone and letrozole levels in boys with constitutional delay of growth and puberty treated with letrozole or testosterone
Kohva, E; Varimo, T; Huopio, H; Tenhola, S; Voutilainen, R; Toppari, J; Miettinen, PJ; Vaaralahti, K; Viinamäki, J; Backman, JT; Hero, M; Raivio, T. 2020. Human reproduction. 35: 257-264 -
Birth Size as a Determinant of Cardiometabolic Risk Factors in Children
Nordman, Henrikki; Jääskeläinen, Jarmo; Voutilainen, Raimo. 2020. Hormone research in paediatrics. 93: 144-153 -
Caffeine content in newborn hair correlates with maternal dietary intake
Lehtonen, Anni; Uusitalo, Lauri; Auriola, Seppo; Backman, Katri; Heinonen, Seppo; Keski-Nisula, Leea; Pasanen, Markku; Pekkanen, Juha; Tuomainen, Tomi-Pekka; Voutilainen, Raimo; Hantunen, Sari; Lehtonen, Marko. 2020. European journal of nutrition. 2021; 60: 193-201 -
Ennenaikainen adrenarke: yleinen, moni-ilmeinen ja hyväennusteinen kehitysvariantti
Liimatta, Jani; Utriainen, Pauliina; Voutilainen, Raimo; Jääskeläinen, Jarmo. 2020. Duodecim. 136: 1419-1426 -
The effect of maternal alcohol and drug abuse on first trimester screening analytes: a retrospective cohort study
Lehikoinen, Anni; Voutilainen, Raimo; Romppanen, Jarkko; Heinonen, Seppo. 2020. Bmc pregnancy and childbirth. 20: 562 -
Tracking of Serum DHEAS Concentrations from Age 1 to 6 Years: A Prospective Cohort Study
Liimatta, Jani; Jääskeläinen, Jarmo; Karvonen, Anne M; Remes, Sami; Voutilainen, Raimo; Pekkanen, Juha. 2020. Journal of the Endocrine Society. 4: 1-11 -
Association of Serum Total Osteocalcin Concentrations with Endogenous Glucocorticoids and Insulin Sensitivity Markers in 12-year-old Children: a Cross-sectional Study
Seppä, Satu; Tenhola, Sirpa; Voutilainen, Raimo. 2019. Frontiers in endocrinology. 10: 798 -
Cardiometabolic Risk Profile Among Young Adult Females With a History of Premature Adrenarche
Liimatta, J; Utriainen, P; Laitinen, T; Voutilainen, R; Jääskeläinen, J. 2019. Journal of the Endocrine Society. 3: 1771-1783 -
Fibroblast Growth Factor 21, Adiponectin, and Irisin as Markers of Unfavorable Metabolic Features in 12-Year-Old Children
Seppä, Satu; Tenhola, Sirpa; Voutilainen, Raimo. 2019. Journal of the Endocrine Society. 3: 825-837 -
Letrozole versus testosterone for promotion of endogenous puberty in boys with constitutional delay of growth and puberty: a randomised controlled phase 3 trial
Varimo, T; Huopio, H; Kariola, L; Tenhola, S; Voutilainen, R; Toppari, J; Toiviainen-Salo, S; Hämäläinen, E; Pulkkinen, MA; Lääperi, M; Tarkkanen, A; Vaaralahti, K; Miettinen, PJ; Hero, M; Raivio, T. 2019. The Lancet. Child & adolescent health. 3: 109-120 -
Analysis by LC-MS/MS of endogenous steroids from human serum, plasma, endometrium and endometriotic tissue
Häkkinen, MR; Heinosalo, T; Saarinen, N; Linnanen, T; Voutilainen, R; Lakka, T; Jääskeläinen, J; Poutanen, M; Auriola, S. 2018. Journal of pharmaceutical and biomedical analysis. 152: 165-172 -
Associations of Dehydroepiandrosterone Sulfate with Cardiometabolic Risk Factors in Prepubertal Children
Mäntyselkä, A; Lindi, V; Viitasalo, A; Eloranta, AM; Ågren, J; Väisänen, S; Voutilainen, R; Laitinen, T; Lakka, TA; Jääskeläinen, J. 2018. Journal of clinical endocrinology and metabolism. 103: 2592-2600 -
Birth size, body composition, and adrenal androgens as determinants of bone mineral density in mid-childhood
Nordman, Henrikki; Voutilainen, Raimo; Laitinen, Tomi; Antikainen, Leena; Jääskeläinen, Jarmo. 2018. Pediatric research. 83: 993-998 -
Children with a History of Premature Adrenarche Have Good Health-Related Quality of Life at the Age of 12 Years
Liimatta, J; Sintonen, H; Utriainen, P; Voutilainen, R; Jääskeläinen, J. 2018. Hormone research in paediatrics. 89: 1-5 -
Delivery of an LGA infant and the maternal risk of diabetes: A prospective cohort study
Hakkarainen, Heidi; Huopio, Hanna; Cederberg, Henna; Voutilainen, Raimo; Heinonen, Seppo. 2018. Primary care diabetes. 12: 364-370 -
Environmental Intolerance, Symptoms and Disability Among Fertile-Aged Women
Vuokko, Aki; Karvala, Kirsi; Lampi, Jussi; Keski-Nisula, Leea; Pasanen, Markku; Voutilainen, Raimo; Pekkanen, Juha; Sainio, Markku. 2018. International journal of environmental research and public health. 15: 293 -
Future risk of metabolic syndrome in women with a previous LGA delivery stratified by gestational glucose tolerance: a prospective cohort study
Hakkarainen, Heidi; Huopio, Hanna; Cederberg, Henna; Voutilainen, Raimo; Heinonen, Seppo. 2018. Bmc pregnancy and childbirth. 18: 326 -
Kuopio birth cohort - design of a Finnish joint research effort for identification of environmental and lifestyle risk factors for the wellbeing of the mother and the newborn child
Huuskonen, P; Keski-Nisula, L; Heinonen, S; Voutilainen, S; Tuomainen, TP; Pekkanen, J; Lampi, J; Lehto, SM; Haaparanta, H; Elomaa, AP; Voutilainen, R; Backman, K; Kokki, H; Kumpulainen, K; Paananen, J; Vähäkangas, K; Pasanen, M. 2018. Bmc pregnancy and childbirth. 18: 381 -
Plasma IL-1 Receptor Antagonist Concentration Has an Inverse Association With Birth Weight in Prepubertal Children
Nordman, Henrikki; Voutilainen, Raimo; Antikainen, Leena; Jääskeläinen Jarmo. 2018. Journal of the Endocrine Society. 2: 232-239 -
Prepubertal Children Exposed to Maternal Gestational Diabetes Have Latent Low-Grade Inflammation
Antikainen, Leena; Jääskeläinen, Jarmo; Nordman, Henrikki; Voutilainen, Raimo; Huopio, Hanna. 2018. Hormone research in paediatrics. 90: 109-115 -
Serum IL-1 Receptor Antagonist Concentrations Associate With Unfavorable Metabolic Features in 12-Year-Old Children
Seppä, Satu; Tenhola, Sirpa; Voutilainen, Raimo. 2018. Journal of the Endocrine Society. 2: 870-881 -
Simultaneous analysis by LC-MS/MS of 22 ketosteroids with hydroxylamine derivatization and underivatized estradiol from human plasma, serum and prostate tissue
Häkkinen, Merja R; Murtola, Teemu; Voutilainen, Raimo; Poutanen, Matti; Linnanen, Tero; Koskivuori, Johanna; Lakka, Timo; Jääskeläinen, Jarmo; Auriola, Seppo. 2018. Journal of pharmaceutical and biomedical analysis. 2019; 164: 642-652 -
Trajectories of Growth and Serum DHEAS and IGF-1 Concentrations in Girls With a History of Premature Adrenarche: Attenuation of the Phenotype by Adulthood
Liimatta, Jani; Utriainen, Pauliina; Voutilainen, Raimo; Jääskelainen, Jarmo. 2018. Frontiers in endocrinology. 9: 375 -
Associations of lifestyle factors with serum dehydroepiandrosterone sulfate and insulin-like growth factor-1 concentration in prepubertal children
Mäntyselkä A, Jääskeläinen J, Eloranta AM, Väistö J, Voutilainen R, Ong K, Brage S, Lakka TA, Lindi V. 2017. Clinical endocrinology. 2018; 88: 234-242 -
Girls with a History of Premature Adrenarche Have Advanced Growth and Pubertal Development at the Age of 12 Years
Liimatta Jani, Utriainen Pauliina, Voutilainen Raimo, Jääskeläinen Jarmo. 2017. Frontiers in endocrinology. 8: 291 -
Prepubertal children born large for gestational age have lower serum DHEAS concentrations than those with a lower birth weight
Nordman Henrikki, Voutilainen Raimo, Antikainen Leena, Jääskeläinen Jarmo. 2017. Pediatric research. 82: 285-289 -
First Morning Voided Urinary Gonadotropin Measurements as an Alternative to the GnRH Test
Demir A, Voutilainen R, Stenman UH, Dunkel L, Albertsson-Wikland K, Norjavaara E. 2016. Hormone research in paediatrics. 85: 301-308 -
Impaired growth and intracranial calcifications in autosomal dominant hypocalcemia caused by a GNA11 mutation
Tenhola Sirpa, Voutilainen Raimo, Reyes Monica, Toiviainen-Salo Sanna, Jüppner Harald, Mäkitie Outi. 2016. European journal of endocrinology. 175: 211-218 -
Maternal drug or alcohol abuse is associated with decreased head size from mid-pregnancy to childhood
Lehikoinen Anni, Ordén Maija-Riitta, Heinonen Seppo, Voutilainen Raimo. 2016. Acta paediatrica. 105: 817-822 -
The risk of metabolic syndrome in women with previous GDM in a long-term follow-up
Hakkarainen H, Huopio H, Cederberg H, Pääkkönen M, Voutilainen R, Heinonen S. 2016. Gynecological endocrinology. 32: 920-925 -
Growth and Cardiovascular Risk Factors in Prepubertal Children Born Large or Small for Gestational Age
Nordman H, Voutilainen R, Laitinen T, Antikainen L, Huopio H, Heinonen S, Jääskeläinen J. 2015. Hormone research in paediatrics. 2016; 85: 11-17 -
Markers of Insulin Sensitivity in 12-Year-Old Children Born from Preeclamptic Pregnancies
Seppä Satu, Voutilainen Raimo, Tenhola Sirpa. 2015. Journal of pediatrics. epub ahead of print 9 May 2015: -
Post-challenge glycemia during pregnancy as a marker of future risk of type 2 diabetes: a prospective cohort study
Hakkarainen Heidi, Huopio Hanna, Cederberg Henna, Pääkkönen Mirja, Voutilainen Raimo, Heinonen Seppo. 2015. Gynecological endocrinology. 31: 573-577 -
Premature Adrenarche - A Common Condition with Variable Presentation
Utriainen P, Laakso S, Liimatta J, Jääskeläinen J, Voutilainen R. 2015. Hormone research in paediatrics. 83: 221-231 -
Ennenaikaisen adrenarken sukupuolierot saattavat johtua erilaisesta kehon rasvakoostumuksesta
Mäntyselkä Aino, Jääskeläinen Jarmo, Lindi Virpi, Viitasalo Anna, Tompuri Tuomo, Voutilainen Raimo, Lakka Timo A. 2014. Duodecim. 130: 101 -
Long-term changes in glucose metabolism after gestational diabetes: a double cohort study
Huopio Hanna, Hakkarainen Heidi, Pääkkönen Mirja, Kuulasmaa Teemu, Voutilainen Raimo, Heinonen Seppo, Cederberg Henna. 2014. Bmc pregnancy and childbirth. 14: 296 -
Premature adrenarche: Etiology, clinical findings, and consequences
Voutilainen Raimo, Jääskeläinen Jarmo. 2014. Journal of steroid biochemistry and molecular biology. 2014: SBMB 4213 No. of Pages 11 -
Serum androgen bioactivity is low in children with premature adrenarche
Liimatta Jani, Laakso Saila, Utriainen Pauliina, Voutilainen Raimo, Palvimo Jorma J, Jääskeläinen Tiina, Jääskeläinen Jarmo. 2014. Pediatric research. 75: 645-650 -
The presentation of adrenarche is sexually dimorphic and modified by body adiposity
Mäntyselkä Aino, Jääskeläinen Jarmo, Lindi Virpi, Viitasalo Anna, Tompuri Tuomo, Voutilainen Raimo, Lakka Timo A. 2014. Journal of clinical endocrinology and metabolism. 99: 3889-3894 -
Adrenocortical hormonal activity in 20-year-old subjects born small or appropriate for gestational age
Todorova B, Salonen M, Jääskeläinen J, Tapio A, Jääskeläinen T, Palvimo J, Turpeinen U, Hämäläinen E, Räsänen M, Tenhola S, Voutilainen R. 2012. Hormone research in paediatrics. 77: 294-304 -
Blood Erythrocyte and Hemoglobin Concentrations in Premature Adrenarche
Utriainen, P; Jääskeläinen, J; Voutilainen, R. 2012. Journal of clinical endocrinology and metabolism. 97: E1-5 -
Catch-Up Growth and Corticosteroids: A Focus on Mechanisms and Clinical Conditions
Voutilainen, R; Tenhola, S. Teoksessa: Victor R. Preedy(toim.) , 2012. Handbook of Growth and Growth Monitoring in Health and Disease, printed in 3 volumes. s. 893-904. Springer -
Lisämunuaiskuoren vajaatoiminta
Jääskeläinen, J; Voutilainen, R. Teoksessa: Korppi, M; Kröger, L; Rantala, H(toim.) , 2012. Lastentautien päivystyskirja, 2. painos. s. 183-186. Kustannus Oy Duodecim -
Polymorphisms of POR, SULT2A1 and HSD11B1 in children with premature adrenarche
Utriainen, P; Laakso, S; Jääskeläinen, J; Voutilainen, R. 2012. Metabolism: clinical and experimental. 61: 1215-1219 -
ESPE from a Personal and Finnish Perspective
Voutilainen, R. Teoksessa: Sippell WG(toim.) , 2011. Sippell WG (ed): ESPE - The First 50 Years. A History of the European Society for Paediatric Endocrinology. s. 122-125. S.Karger AG -
Interleukins 1alfa and 1 beta as regulators of steroidogenesis in human NCI-H295R adrenocortical cells
Tkachenko Irina V, Jääskeläinen Tiina, Jääskeläinen Jarmo, Palvimo Jorma J, Voutilainen Raimo. 2011. Steroids. 76: 1103-1115 -
Circulating TNF-alpha and IL-6 concentrations and TNF-alpha-308 G > A polymorphism in children with premature adrenarche
Utriainen P, Jääskeläinen J, Gröhn O, Kuusisto J, Pulkki K & Voutilainen R. 2010. Frontiers in endocrinology. 1: doi: 10.3389/fendo.2010.00006, Article 6: 1-6 -
Ennenaikainen adrenarke. Mitä tehdä, kun lapsen hiki haisee?
Utriainen P, Jääskeläinen J & Voutilainen R. 2010. Lääkärilehti. 65: 3875-3881 -
Polymorphism Pro12Ala of PPARG in Prepubertal Children with Premature Adrenarche and Its Association with Growth in Healthy Children
Laakso S, Utriainen P, Laakso M, Voutilainen R & Jääskeläinen J. 2010. Hormone research in paediatrics. 74: 365-371 -
Serum Anti-Müllerian Hormone Concentrations in Prepubertal Girls with and without Premature Adrenarche: The Influence Of Body Mass Index
Utriainen P, Jääskeläinen J & Voutilainen R. 2010. Hormone research in paediatrics. 74: 207-211 -
Serum Concentrations of Adrenal Steroids and Their Precursors as a Measure of Maturity of Adrenocortical Function in Very Premature Newborn
Nykänen P, Heinonen K, Riepe FG, Sippell WG & Voutilainen R. 2010. Hormone research in paediatrics. 74: 358-364 -
Serum glucocorticoids and adiponectin associate with insulin resistance in children born small for gestational age
S Tenhola, B Todorova, J Jääskeläinen, OA Jänne, T Raivio & R Voutilainen. 2010. European journal of endocrinology. 162: 551-557 -
Tracking Serum Lipid Levels and the Association of Cholesterol Concentrations, Blood Pressure and Cigarette Smoking With Carotid Artery Intima-Media Thickness in Young Adults Born Small for Gestational Age
Salonen M, Tenhola S, Laitinen T, Lyyra-Laitinen T, Romppanen J, Jääskeläinen J & Voutilainen R. 2010. Circulation journal. 74: 2419-2425 -
Body composition and bone mineral density in children with premature adrenarche and the association of LRP5 gene polymorphisms with bone mineral density
Utriainen P, Jääskeläinen J, Saarinen A, Vanninen E, Mäkitie O, Voutilainen R. 2009. Journal of clinical endocrinology and metabolism. 94: 4144-4151 -
Continuum of phenotypes and sympathoadrenal function in premature adrenarche
Utriainen P, Voutilainen R, Jääskeläinen J. 2009. European journal of endocrinology. 160: 657-665 -
Expression of adrenomedullin in human ovaries, ovarian sex cord-stromal tumors and cultured granulosa-luteal cells
Liu J, Bützow R, Hydén-Granskog C, Voutilainen R. 2009. Gynecological endocrinology. 25: 96-103 -
Girls with premature adrenarche have accelerated early childhood growth
Utriainen P, Voutilainen R, Jääskeläinen J. 2009. Journal of pediatrics. 154: 882-887 -
LRP5 in premature adrenarche and metabolic characteristics of prepubertal children
Lappalainen S, Saarinen A, Utriainen P, Voutilainen R, Jääskeläinen J, Mäkitie O. 2009. Clinical endocrinology. 70: 725-731 -
Lisämunuaiskuoren vajaatoiminta
Jääskeläinen J, Voutilainen R. Teoksessa: Korppi M, Kröger L, Rantala H(toim.) , 2009. Lastentautien päivystyskirja. 1. p.. s. 156-159. Duodecim -
ACTH receptor promoter polymorphism associates with severity of premature adrenarche and modulates hypothalamo-pituitary-adrenal axis in children
Lappalainen S, Utriainen P, Kuulasmaa T, Voutilainen R, Jääskeläinen J. 2008. Pediatric research. 63: 410-414 -
Androgen receptor gene CAG repeat length in women with metabolic syndrome
Jääskeläinen J, Korhonen S, Kuulasmaa T, Kurl S, Niskanen L, Vanhala M, Hippeläinen M, Voutilainen R, Heinonen S. 2008. Gynecological endocrinology. 24: 411-416 -
Androgen receptor gene CAG repeat polymorphism and X-chromosome inactivation in children with premature adrenarche
Lappalainen S, Utriainen P, Kuulasmaa T, Voutilainen R, Jääskeläinen J. 2008. Journal of clinical endocrinology and metabolism. 93: 1304-1309 -
Leukemia inhibitory factor as a regulator of steroidogenesis in human NCI-H295R adrenocortical cells
Mikhaylova IV, Jääskeläinen T, Jääskeläinen J, Palvimo JJ, Voutilainen R. 2008. Journal of endocrinology. 199: 435-444 -
WNT-4 mRNA expression in human adrenocortical tumors and cultured adrenal cells
Kuulasmaa T, Jääskeläinen J, Suppola S, Pietiläinen T, Heikkilä P, Aaltomaa S, Kosma V-M, Voutilainen R. 2008. Hormone and metabolic research. 40: 668-673 -
Childhood metabolic syndrome and its components in premature adrenarche
Utriainen P, Jääskeläinen J, Romppanen J, Voutilainen R. 2007. Journal of clinical endocrinology and metabolism. 92: 4282-4285 -
Circulating glucocorticoid bioactivity and serum cortisol concentrations in premature infants: the influence of exogenous glucocorticoids and clinical factors
Nykänen P, Raivio T, Heinonen K, Jänne OA, Voutilainen R. 2007. European journal of endocrinology. 156: 577-583 -
Early hypoadrenalism in premature infants at risk for bronchopulmonary dysplasia or death
Nykänen P, Anttila E, Heinonen K, Hallman M, Voutilainen R. 2007. Acta paediatrica. 96: 1600-1605 -
Tumor necrosis factor-alfa regulates steroidogenesis, apoptosis, and cell viability in the human adrenocortical cell line NCI-H295R
Mikhaylova IV, Kuulasmaa T, Jääskeläinen J, Voutilainen R. 2007. Endocrinology. 148: 386-392 -
Inhibition of DNA methylation increases follistatin expression and secretion in the human adrenocortical cell line NCI-H295R
Utriainen P, Liu J, Kuulasmaa T, Voutilainen R. 2006. Journal of endocrinology. 188: 305-310 -
Maternal preeclampsia predicts elevated blood pressure in 12-year-old children: Evaluation by ambulatory blood pressure monitoring
Tenhola S, Rahiala E, Halonen P, Vanninen E, Voutilainen R. 2006. Pediatric research. 59: 320-324 -
Androgen receptor gene CAG length polymorphism in women with polycystic ovary syndrome
Jääskeläinen J, Korhonen S, Voutilainen R, Hippeläinen M, Heinonen S. 2005. Fertility and sterility. 83: 1724-1728 -
Association of serum lipid concentrations, insulin resistance index and catch-up growth with serum cortisol/cortisone ratio by liquid chromatography tandem mass spectrometry in children born small for gestational age
Tenhola S, Turpeinen U, Halonen P, Hämäläinen E, Voutilainen R. 2005. Pediatric research. 58: 467-471 -
Preeclampsia and androgen receptor gene CAG repeat length: results from both children and women
Saarela T, Jääskeläinen J, Tenhola S, Voutilainen R, Heinonen S. 2005. Journal of assisted reproduction and genetics. 22: 269-275 -
Pretreatment cortisol values may predict responses to hydrocortisone administration for the prevention of bronchopulmonary dysplasia in high-risk infants
Peltoniemi O, Kari A, Heinonen K, Saarela T, Nikolajev K, Andersson S, Voutilainen R, Hallman M. 2005. Journal of pediatrics. 146: 632-637 -
Serum markers of GH and insulin action in 12-year-old children born small for gestational age
Tenhola S, Halonen P, Jääskeläinen J, Voutilainen R. 2005. European journal of endocrinology. 125: 335-340 -
Transcription factors GATA-6, SF-1, and cell proliferation in human adrenocortical tumors
Kiiveri S, Liu J, Arola J, Heikkilä P, Kuulasmaa T, Lehtonen E, Voutilainen R, Heikinheimo M. 2005. Molecular and cellular endocrinology. 233: 47-56 -
DNA methylation affects cell proliferation, cortisol secretion and steroidogenic gene expression in human adrenocortical NCI-H295R cells
Liu J, Li X-D, Vaheri A, Voutilainen R. 2004. Journal of molecular endocrinology. 33: 651-662 -
Investigation of the role of SDHB inactivation in sporadic phaeochromocytoma and neuroblastoma
Astuti D, Morris M, Krona C, Abel F, Gentle D, Martinsson T, Kogner P, Neumann HPH, Voutilainen R, Eng C, Rustin P, Latif F, Maher ER. 2004. British journal of cancer. 91: 1835-1841 -
Serum dehydroepiandrosterone sulfate concentration as an indicator of adrenocortical suppression during inhaled steroid therapy in adult asthmatic patients
Kannisto S, Laatikainen A, Taivainen A, Savolainen K, Tukiainen H, Voutilainen R. 2004. European journal of endocrinology. 150: 687-690 -
Transcription factors GATA-4 and GATA-6 human adrenocortical tumors
Kiiveri S, Liu J, Heikkilä P, Arola J, Lehtonen E, Voutilainen R, Heikinheimo M. 2004. Endocrine research. 30: 919-923 -
cAMP-dependent protein kinase activation inhibits proliferation and enhances apoptotic effect of tumor necrosis factor-alfa in NCI-H295R adrenocortical cells
Liu J, Li X-D, Ora A, Heikkilä P, Vaheri A, Voutilainen R. 2004. Journal of molecular endocrinology. 33: 511-522 -
Blood pressure, serum lipids, fasting insulin, and adrenal hormones in 12-year-old children born with maternal preeclampsia
Tenhola S, Rahiala E, Martikainen A, Halonen P, Voutilainen R. 2003. Journal of clinical endocrinology and metabolism. 88: 1217-1222 -
Bone mineral density in long-term survivors of childhood cancer
Arikoski P, Voutilainen R, Kröger H, Kröger H. 2003. Journal of pediatric endocrinology and metabolism. 16: 343-353 -
Expression of activin/inhibin signaling components in the human adrenal gland and the effects of activins and inhibins on adrenocortical steroidogenesis and apoptosis
Vänttinen T, Liu J, Kuulasmaa T, Kivinen P, Voutilainen R. 2003. Journal of endocrinology. 178: 479-489 -
Expression of betaglycan, an inhibin coreceptor, in normal human ovaries and ovarian sex cord-stromal tumors and its regulation in cultured human granulosa-luteal cells
Liu J, Kuulasmaa T, Kosma V-M, Bützow R, Vänttinen T, Hydén-Granskog C, Voutilainen R. 2003. Journal of clinical endocrinology and metabolism. 88: 5002-5008 -
Acute insulin response tests for the differential diagnosis of congenital hyperinsulinism
Huopio H, Jääskeläinen J, Komulainen J, Miettinen R, Kärkkäinen P, Laakso M, Tapanainen P, Voutilainen R, Otonkoski T. 2002. Journal of clinical endocrinology and metabolism. 87: 4502-4507 -
Association of H19 promoter methylation with the expression of H19 and IGF-II genes in adrenocortical tumors
Gao Z-H, Suppola S, Liu J, Heikkilä P, Jänne J, Voutilainen R. 2002. Journal of clinical endocrinology and metabolism. 87: 1170-1176 -
Biochemical markers of bone metabolism in relation to adrenocortical and growth suppression during the initiation phase of inhaled steroid therapy
Kannisto S, Korppi M, Arikoski P, Remes K, Voutilainen R. 2002. Pediatric research. 52: 258-262 -
Biphasic regulation of activin A secretion by gonadotropins in cultured human ovarian granulosa-luteal cells leads to decreasing activin: inhibin ratios during continuing gonadotropin stimulation
Vänttinen T, Liu J, Hyden-Granskog C, Voutilainen R. 2002. Journal of endocrinology. 172: 557-563 -
Differential expression of GATA-4 and GATA-6 in fetal and adult mouse and human adrenal tissue
Kiiveri S, Liu J, Westerholm-Ormio M, Narita N, Wilson DB, Voutilainen R, Heikinheimo M. 2002. Endocrinology. 143: 3136-3143 -
Efficacy and safety of inhaled steroid and cromone treatment in school-age children: A randomized pragmatic pilot study
Kannisto S, Voutilainen R, Remes K, Korppi M. 2002. Pediatric allergy and immunology. 13: 24-30 -
Expression of activin/inhibin receptor and binding protein genes and regulation of activin/inhibin peptide secretion in human adrenocortical cells
Vänttinen T, Kuulasmaa T, Liu J, Voutilainen R. 2002. Journal of clinical endocrinology and metabolism. 87: 4257-4263 -
Gonadotrophins inhibit the expression of insulin-like growth factor binding protein-related protein-2 mRNA in cultured human granulosa-luteal cells
Liu J, Kosma V-M, Vänttinen T, Hyden-Granskog C, Voutilainen R. 2002. Molecular human reproduction. 8: 136-141 -
Increased adrenocortical and adrenomedullary hormonal activity in 12-year-old children born small for gestational age
Tenhola S, Martikainen A, Rahiala E, Parviainen M, Halonen P, Voutilainen R. 2002. Journal of pediatrics. 141: 477-482 -
Lumbar bone mineral density in normal subjects aged 3-6 years: a prospective study
Arikoski P, Komulainen J, Voutilainen R, Kröger L, Kröger H. 2002. Acta paediatrica. 91: 287-291 -
Regulation of follistatin-related gene (FLRG) expression by protein kinase C and prostaglandin E2 in cultured granulosa-luteal cells
Liu J, Vänttinen T, Hyden-Granskog C, Voutilainen R. 2002. Molecular human reproduction. 8: 992-997 -
Transactivation assay for determination of glucocorticoid bioactivity in human serum
Raivio T, Palvimo JJ, Kannisto S, Voutilainen R, Jänne OA. 2002. Journal of clinical endocrinology and metabolism. 87: 3740-3744 -
Gonadotrophins inhibit and activin induces expression of inhibin /activin beta-B subunit mRNA in cultured human granulosa-luteal cells
Liu J, Hydén-Granskog C, Voutilainen R. 2001. Molecular human reproduction. 7: 319-323 -
Inhibin/activin beta-B-subunit expression in pheochromocytomas favors benign diagnosis
Salmenkivi K, Arola J, Voutilainen R, Ilvesmäki V, Haglund C, Kahri AI, Heikkilä P, Liu J. 2001. Journal of clinical endocrinology and metabolism. 86: 2231-2235 -
Lasten riisitaudista aikuisten osteomalasiaan
Välimäki MJ, Voutilainen R, Kaitila I, Tuomi T. 2001. Duodecim. 117: 2171-2180 -
RASSF1A promoter region CpG island hypermethylation in phaeochromocytomas and neuroblastoma tumours
Astuti D, Agathanggelou A, Honorio S, Dallol A, Martinsson T, Kogner P, Cummins C, Neumann HPH, Voutilainen R, Dahia P, Eng C, Maher ER, Latif F. 2001. Oncogene. 20: 7573-7577 -
Serum dehydroepiandrosterone sulfate concentration as an indicator of adrenocortical suppression in asthmatic children treated with inhaled steroids
Kannisto S, Korppi M, Remes K, Voutilainen R. 2001. Journal of clinical endocrinology and metabolism. 86: 4908-4912 -
Sexual function and fertility in adult females and males with congenital adrenal hyperplasia
Jääskeläinen J, Tiitinen A, Voutilainen R. 2001. Hormone research. 56: 73-80 -
Adrenal suppression, evaluated by a low dose adrenocorticotropin test, and growth in asthmatic children treated with inhale steroids
Kannisto S, Korppi M, Remes K, Voutilainen R. 2000. Journal of clinical endocrinology and metabolism. 85: 652-657 -
Child rate, pregnancy outcome and ovarian function in females with classical 21-hydroxylase deficiency
Jääskeläinen J, Hippeläinen M, Kiekara O, Voutilainen R. 2000. Acta obstetricia et gynecologica scandinavica. 79: 687-692 -
Comparison between low- and standard-dose ACTH tests in premature infants at risk for chronic lung disease
Nykänen P, Heinonen K, Voutilainen R. 2000. Hormone research. (1999)52: 274-278 -
Expression of activin A and its receptors in human pheochromocytomas
Liu J, Heikkilä P, Kahri AI, Voutilainen R. 2000. Journal of endocrinology. 165: 503-508 -
Expression of inhibin alpha in adrenocortical tumours reflects the hormonal status of the neoplasm
Arola J, Liu J, Heikkilä P, Ilvesmäki V, Salmenkivi K, Voutilainen R, Kahri AI. 2000. Journal of endocrinology. 165: 223-229 -
Expression of low and high density lipoprotein receptor genes in human adrenals
Liu J, Heikkilä P, Meng Q-H, Kahri AI, Tikkanen MJ, Voutilainen R. 2000. European journal of endocrinology. 142: 677-682 -
Long-term outcome of classical 21-hydroxylase deficiency: diagnosis, complications and quality of life
Jääskeläinen J, Voutilainen R. 2000. Acta paediatrica. 89: 183-187 -
Pituitary gonadal axis and child rate in males with classical 21-hydroxylase deficiency
Jääskeläinen J, Kiekara O, Hippeläinen M, Voutilainen R. 2000. Journal of endocrinological investigation. 23: 23-27 -
Regulation of immunoreactive inhibin A and B secretion in cultured human granulosa-luteal cells by gonadotropins, activin A and insulin-like growth factor type-1 receptor
Vänttinen T, Liu J, Hyden-Granskog C, Parviainen M, Penttilä I, Voutilainen R. 2000. Journal of endocrinology. 167: 289-294 -
Serum lipid concentrations and growth characteristics in 12-year-old children born small for gestational age
Tenhola S, Martikainen A, Rahiala E, Herrgård E, Halonen P, Voutilainen R. 2000. Pediatric research. 48: 623-628 -
Alterations in bone turnover and impaired development of bone mineral density in newly diagnosed children with cancer: a 1-year prospective study
Arikoski P, Komulainen J, Riikonen P, Voutilainen R, Knip M, Kröger H. 1999. Journal of clinical endocrinology and metabolism. 84: 3174-3181 -
Bone morphogenetic protein-6 is a marker of serous acinar cell differentiation in normal and neoplastic human salivary gland
Heikinheimo AK, Laine MA, Ritvos OV-P, Voutilainen RJ, Hogan BLM, Leivo IV. 1999. Cancer research. 59: 5815-5821 -
Disturbance in bone turnover in children with a malignancy at completion of chemotherapy
Arikoski P, Kröger H, Riikonen P, Parviainen M, Voutilainen R, Komulainen J. 1999. Pediatric blood and cancer. 33: 455-461 -
Impaired development of bone mineral density during chemotherapy: a prospective analysis of 46 children newly diagnosed with cancer
Arikoski P, Komulainen J, Riikonen P, Parviainen M, Jurvelin JS, Voutilainen R, Kröger H. 1999. Journal of bone and mineral research. 14: 2002-2009 -
Lisämunuaiskuoren vajaatoiminta
Jääskeläinen J, Voutilainen R. Teoksessa: Jääskeläinen J, Herrgård E, Komulainen J, Tikanoja T, Korppi M(toim.) , 1999. Lastenlääkärin päivystyskirja. s. 107-109. KYS, lastenklinikka -
Reduced bone density at completion of chemotherapy for a malignancy
Arikoski P, Komulainen J, Riikonen P, Jurvelin JS, Voutilainen R, Kröger H. 1999. Archives of disease in childhood. 80: 143-148 -
Regulation of neuropeptide Y mRNA expression in cultured human pheochromocytoma cells
Liu J, Kahri AI, Heikkilä P, Voutilainen R. 1999. European journal of endocrinology. 141: 431-435 -
Tracing past population migrations: genealogy of steroid 21-hydroxylase (CYP21) gene mutations in Finland
Levo A, Jääskeläinen J, Sistonen P, Sirén M-K, Voutilainen R, Partanen J. 1999. European journal of human genetics. 7: 188-196 -
pG2 gene expression and its regulation in human adrenocortical and medullary tumors
Liu J, Voutilainen R, Heikkilä P, Kahri AI. 1999. European journal of endocrinology. 140: 590-596 -
Adrenocortical cells are the site of secretion and action of insulin-like growth factors and TNF-alpha
Voutilainen R. 1998. Hormone and metabolic research. 30: 432-435 -
Expression of insulin-like growth factor binding protein 1-6 genes in adrenocortical tumors and pheochromocytomas
Ilvesmäki V, Liu J, Heikkilä P, Kahri AI, Voutilainen R. 1998. Hormone and metabolic research. 30: 619-623 -
Miten opettaja voi parantaa opetustaan - esimerkki lastentautien perusopetuksesta
Martikainen A, Voutilainen R. 1998. Duodecim. 114: 2174-2180 -
Reduced bone mineral density in long-term survivors of childhood acute lymphoblastic leukemia
Arikoski P, Komulainen J, Voutilainen R, Riikonen P, Parviainen M, Tapanainen P, Knip M, Kröger H. 1998. Journal of pediatric hematology oncology. 20: 234-240 -
Adrenomedullin gene expression and its different regulation in human adrenocortical and medullary tumors
Liu J, Kahri AI, Heikkilä P, Voutilainen R. 1997. Journal of endocrinology. 155: 483-490 -
Expression patterns of the c-myc gene in adrenocortical tumors and pheochromocytomas
Liu J, Voutilainen R, Kahri AI, Heikkilä P. 1997. Journal of endocrinology. 152: 175-181 -
Genetic predisposition to phaeochromocytoma: analysis of candidate genes GDNF, RET and VHL
Woodward ER, Eng C, McMahon R, Voutilainen R, Affara NA, Ponder BAJ, Maher ER. 1997. Human molecular genetics. 6: 1051-1056 -
Genomic imprinting and the endometrial cycle. The expression of the imprinted gene H19 in the human female reproductive organs
Ariel I, Weinstein D, Voutilainen R, Schneider T, Lustig-Yariv O, de Groot N, Hochenberg A. 1997. Diagnostic molecular pathology. 6: 17-25 -
Growth of patients with 21-Hydroxylase deficiency: An analysis of the factors influencing adult height
Jääskeläinen J, Voutilainen R. 1997. Pediatric research. 41: 30-33 -
Population-wide evaluation of disease manifestation in relation to molecular genotype in steroid 21-hydroxylase (CYP21) deficiency: Good correlation in a well defined population
Jääskeläinen J, Levo A, Voutilainen R, Partanen J. 1997. Journal of clinical endocrinology and metabolism. 82: 3293-3297 -
Ribonucleic acid expression of the CLA-1 gene, a human homolog to mouse high density lipoprotein receptor SR-BI, in human adrenal tumors and cultured adrenal cells
Liu J, Voutilainen R, Heikkilä P, Kahri AI. 1997. Journal of clinical endocrinology and metabolism. 82: 2522-2527 -
Ribonucleic acid expression of the clustered imprinted genes, p57KIP2, insulin-like growth factor II, and H19, in adrenal tumors and cultured adrenal cells
Liu J, Kahri AI, Heikkilä P, Voutilainen R. 1997. Journal of clinical endocrinology and metabolism. 82: 1766-1771 -
21-hydroksylaasivajeen sikiökautinen diagnostiikka ja deksametasonihoito
Jääskeläinen J, Partanen J, Hippeläinen M, Levo A, Voutilainen R. 1996. Duodecim. 112: 1258-1263 -
Bone mineral density in relation to glucocorticoid substitution therapy in adult patients with 21-hydroxylase deficiency
Jääskeläinen J, Voutilainen R. 1996. Clinical endocrinology. 45: 707-713 -
Expression of insulin-like growth factor (IGF), IGF-binding protein, and IGF receptor messenger ribonucleic acids in normal and polycystic ovaries
Voutilainen R, Franks S, Mason HD, Martikainen H. 1996. Journal of clinical endocrinology and metabolism. 81: 1003-1008 -
Expression of the c-myc gene in human adrenals: regulation by adrenocorticotropin in primary cultures
Liu J, Voutilainen R, Kahri AI, Heikkilä P. 1996. Journal of endocrinology. 148: 523-529 -
Expression of the steroidogenic acute regulatory protein mRNA in adrenal tumors and cultured adrenal cells
Liu J, Heikkilä P, Kahri AI, Voutilainen R. 1996. Journal of endocrinology. 150: 43-50 -
Increase in first morning voided urinary luteinizing hormone levels precedes the physical onset of puberty
Demir A, Voutilainen R, Juul A, Dunkel L, Alfthan H, Skakkebaek NE, Stenman U-H. 1996. Journal of clinical endocrinology and metabolism. 81: 2963-2967 -
Serum cortisol, dehydroepiandrosterone sulfate, and steroid-binding globulins in preterm neonates: effect of gestational age and dexamethasone therapy
Kari MA, Raivio KO, Stenman U-H, Voutilainen R. 1996. Pediatric research. 40: 319-324 -
XXII Spring Meeting of The Finnish Endocrine Society. Kuopio, Finland 10.-11.5.1996. Program and Abstracts
Niskanen L, Voutilainen R. 1996. Kuopio University Publications D. Medical Sciences. . - -
Age-related course of urinary gonadotropins in children
Demir A, Dunkel L, Stenman U-H, Voutilainen R. 1995. Journal of clinical endocrinology and metabolism -
Follow up of growth and steroids in premature adrenarche
Pere A, Perheentupa J, Peter M, Voutilainen R. 1995. European journal of pediatrics. 154: 346-352 -
H19 and insulin-like growth factor-II gene expression in adrenal tumors and cultured adrenal cells
Liu J, Kahri AI, Heikkilä P, Ilvesmäki V, Voutilainen R. 1995. Journal of clinical endocrinology and metabolism. 80: 492-496 -
Lapsuusiän lihavuuden hoidon järjestäminen
Komulainen J, Pietikäinen M, Kalavainen M, Voutilainen R. 1995. Lääkärilehti. 50: 1440-1441 -
Primary hypogonadism in females with infantile onset spinocerebellar ataxia
Koskinen T, Pihko H, Voutilainen R. 1995. Neuropediatrics. 26: 263-266 -
The expression of insulin-like growth factor and its protein mRNA in the endometrium of postmenopausal patients with breast cancer receiving tamoxifen
Laatikainen TJ, Tomás EI, Voutilainen RJ. 1995. Cancer. 76: 1406-1410 -
What is the function of adrenal inhibins?
Voutilainen R. 1995. European journal of endocrinology -
Kasvutekijät ja sytokiinit hormonivaikutusten välittäjinä
Ilvesmäki V, Voutilainen R. 1994. Duodecim. 110: 949-957 -
A prospective study on clinical and metabolic associates of proteinuria in patients with type 2 diabetes mellitus
Niskanen L, Voutilainen R, Teräsvirta M, Lehtinen J, Teppo AM, Groop L, Uusitupa M. 1993. Diabetic medicine. 10: 543-549