Raimo Voutilainen

Antikainen, Leena; Jääskeläinen, Jarmo; Nordman, Henrikki; Voutilainen, Raimo; Huopio, Hanna. 2021. Boys but Not Girls Exposed to Maternal Gestational Diabetes Mellitus Have Unfavorable Fat Distribution Hormone research in paediatrics 94 5-6: 194-200. 2021

Lehikoinen, Anni; Sorri, Iiris; Voutilainen, Raimo; Heinonen, Seppo. 2021. Optical coherence tomography shows decreased thickness of retinal nerve fibre layer among foetal alcohol exposed young adults in a case-control study Acta ophthalmologica 99 7: e1243-e1244. 2021

Ruohomäki, Aleksi; Toffol, Elena; Airaksinen, Ville; Backman, Katri; Voutilainen, Raimo; Hantunen, Sari; Tuomainen, Tomi-Pekka; Lampi, Jussi; Kokki, Hannu; Luoma, Ilona; Kumpulainen, Kirsti; Heinonen, Seppo; Keski-Nisula, Leea; Pekkanen, Juha; Pasanen, Markku; Lehto, Soili M.. 2021. The impact of postpartum depressive symptoms on self-reported infant health and analgesic consumption at the age of 12 months: A prospective cohort study Journal of psychiatric research 136: 388-397. 2021

Seppä, Satu; Kuiri-Hänninen, Tanja; Holopainen, Elina; Voutilainen, Raimo. 2021. Diagnosis and management of primary amenorrhea and female delayed puberty European journal of endocrinology 184 6: R225-R242. 2021

Tennilä, Jussi; Jääskeläinen, Jarmo; Utriainen, Pauliina; Voutilainen, Raimo; Häkkinen, Merja; Auriola, Seppo; Morin-Papunen, Laure; Liimatta, Jani. 2021. PCOS Features and Steroid Profiles Among Young Adult Women with a History of Premature Adrenarche Journal of clinical endocrinology and metabolism 106 9: e3335-e3345. 2021

Varimo, Tero; Miettinen, Päivi J; Laine, Tiina; Salonen, Pia; Tenhola, Sirpa; Voutilainen, Raimo; Huopio, Hanna; Hero, Matti; Raivio, Taneli. 2021. Bone structure assessed with pQCT in prepubertal males with delayed puberty or congenital hypogonadotropic hypogonadism Clinical endocrinology 95 1: 107-116. 2021

Huttunen, Heta; Varimo, Tero; Huopio, Hanna; Voutilainen, Raimo; Tenhola, Sirpa; Miettinen, Päivi J.; Raivio, Taneli; Hero, Matti. 2021. Serum testosterone and oestradiol predict the growth response during puberty promoting treatment Clinical endocrinology 2022; 96 2: 220-226. 2021

Liimatta, Jani; Jääskeläinen, Jarmo; Karvonen, Anne M; Remes, Sami; Voutilainen, Raimo; Pekkanen, Juha. 2020. Tracking of Serum DHEAS Concentrations from Age 1 to 6 Years: A Prospective Cohort Study Journal of the Endocrine Society 4 2: 1-11. 2020

Nordman, Henrikki; Jääskeläinen, Jarmo; Voutilainen, Raimo. 2020. Birth Size as a Determinant of Cardiometabolic Risk Factors in Children Hormone research in paediatrics 93 3: 144-153. 2020

Liimatta, Jani; Utriainen, Pauliina; Voutilainen, Raimo; Jääskeläinen, Jarmo. 2020. Ennenaikainen adrenarke: yleinen, moni-ilmeinen ja hyväennusteinen kehitysvariantti Duodecim 136 12: 1419-1426. 2020

Lehtonen, Anni; Uusitalo, Lauri; Auriola, Seppo; Backman, Katri; Heinonen, Seppo; Keski-Nisula, Leea; Pasanen, Markku; Pekkanen, Juha; Tuomainen, Tomi-Pekka; Voutilainen, Raimo; Hantunen, Sari; Lehtonen, Marko. 2020. Caffeine content in newborn hair correlates with maternal dietary intake European journal of nutrition 2021; 60: 193-201. 2020

Lehikoinen, Anni; Voutilainen, Raimo; Romppanen, Jarkko; Heinonen, Seppo. 2020. The effect of maternal alcohol and drug abuse on first trimester screening analytes: a retrospective cohort study Bmc pregnancy and childbirth 20: 562. 2020

Kohva, E; Varimo, T; Huopio, H; Tenhola, S; Voutilainen, R; Toppari, J; Miettinen, PJ; Vaaralahti, K; Viinamäki, J; Backman, JT; Hero, M; Raivio, T. 2020. Anti-Müllerian hormone and letrozole levels in boys with constitutional delay of growth and puberty treated with letrozole or testosterone Human reproduction 35 2: 257-264. 2020

Liimatta, J; Utriainen, P; Laitinen, T; Voutilainen, R; Jääskeläinen, J. 2019. Cardiometabolic Risk Profile Among Young Adult Females With a History of Premature Adrenarche Journal of the Endocrine Society 3 10: 1771-1783. 2019

Seppä, Satu; Tenhola, Sirpa; Voutilainen, Raimo. 2019. Association of Serum Total Osteocalcin Concentrations with Endogenous Glucocorticoids and Insulin Sensitivity Markers in 12-year-old Children: a Cross-sectional Study Frontiers in endocrinology 10: 798. 2019

Seppä, Satu; Tenhola, Sirpa; Voutilainen, Raimo. 2019. Fibroblast Growth Factor 21, Adiponectin, and Irisin as Markers of Unfavorable Metabolic Features in 12-Year-Old Children Journal of the Endocrine Society 3 4: 825-837. 2019

Varimo, T; Huopio, H; Kariola, L; Tenhola, S; Voutilainen, R; Toppari, J; Toiviainen-Salo, S; Hämäläinen, E; Pulkkinen, MA; Lääperi, M; Tarkkanen, A; Vaaralahti, K; Miettinen, PJ; Hero, M; Raivio, T. 2019. Letrozole versus testosterone for promotion of endogenous puberty in boys with constitutional delay of growth and puberty: a randomised controlled phase 3 trial The Lancet. Child & adolescent health 3 2: 109-120. 2019

Liimatta, Jani; Utriainen, Pauliina; Voutilainen, Raimo; Jääskelainen, Jarmo. 2018. Trajectories of Growth and Serum DHEAS and IGF-1 Concentrations in Girls With a History of Premature Adrenarche: Attenuation of the Phenotype by Adulthood Frontiers in endocrinology 9: 375. 2018

Vuokko, Aki; Karvala, Kirsi; Lampi, Jussi; Keski-Nisula, Leea; Pasanen, Markku; Voutilainen, Raimo; Pekkanen, Juha; Sainio, Markku. 2018. Environmental Intolerance, Symptoms and Disability Among Fertile-Aged Women. International Journal of Environmental Research and Public Health 15 2: 293. 2018

Seppä, Satu; Tenhola, Sirpa; Voutilainen, Raimo. 2018. Serum IL-1 Receptor Antagonist Concentrations Associate With Unfavorable Metabolic Features in 12-Year-Old Children Journal of the Endocrine Society 2 8: 870-881. 2018

Nordman, Henrikki; Voutilainen, Raimo; Laitinen, Tomi; Antikainen, Leena; Jääskeläinen, Jarmo. 2018. Birth size, body composition, and adrenal androgens as determinants of bone mineral density in mid-childhood. PEDIATRIC RESEARCH 83 5: 993-998. 2018

Nordman, Henrikki; Voutilainen, Raimo; Antikainen, Leena; Jääskeläinen Jarmo. 2018. Plasma IL-1 Receptor Antagonist Concentration Has an Inverse Association With Birth Weight in Prepubertal Children. Journal of the endocrine society 2 3: 232-239. 2018

Mäntyselkä, A; Lindi, V; Viitasalo, A; Eloranta, AM; Ågren, J; Väisänen, S; Voutilainen, R; Laitinen, T; Lakka, TA; Jääskeläinen, J. 2018. Associations of Dehydroepiandrosterone Sulfate with Cardiometabolic Risk Factors in Prepubertal Children JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM 103 7: 2592-2600. 2018

Hakkarainen, Heidi; Huopio, Hanna; Cederberg, Henna; Voutilainen, Raimo; Heinonen, Seppo. 2018. Future risk of metabolic syndrome in women with a previous LGA delivery stratified by gestational glucose tolerance: a prospective cohort study Bmc pregnancy and childbirth 18: 326. 2018

Liimatta, J; Sintonen, H; Utriainen, P; Voutilainen, R; Jääskeläinen, J. 2018. Children with a History of Premature Adrenarche Have Good Health-Related Quality of Life at the Age of 12 Years. HORMONE RESEARCH IN PAEDIATRICS 89 3: 1-5. 2018

Häkkinen, MR; Heinosalo, T; Saarinen, N; Linnanen, T; Voutilainen, R; Lakka, T; Jääskeläinen, J; Poutanen, M; Auriola, S. 2018. Analysis by LC-MS/MS of endogenous steroids from human serum, plasma, endometrium and endometriotic tissue JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS 152: 165-172. 2018

Häkkinen, Merja R; Murtola, Teemu; Voutilainen, Raimo; Poutanen, Matti; Linnanen, Tero; Koskivuori, Johanna; Lakka, Timo; Jääskeläinen, Jarmo; Auriola, Seppo. 2018. Simultaneous analysis by LC-MS/MS of 22 ketosteroids with hydroxylamine derivatization and underivatized estradiol from human plasma, serum and prostate tissue JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS 2019; 164: 642-652. 2018

Huuskonen, P; Keski-Nisula, L; Heinonen, S; Voutilainen, S; Tuomainen, TP; Pekkanen, J; Lampi, J; Lehto, SM; Haaparanta, H; Elomaa, AP; Voutilainen, R; Backman, K; Kokki, H; Kumpulainen, K; Paananen, J; Vähäkangas, K; Pasanen, M. 2018. Kuopio birth cohort - design of a Finnish joint research effort for identification of environmental and lifestyle risk factors for the wellbeing of the mother and the newborn child BMC PREGNANCY AND CHILDBIRTH 18: 381. 2018

Hakkarainen, Heidi; Huopio, Hanna; Cederberg, Henna; Voutilainen, Raimo; Heinonen, Seppo. 2018. Delivery of an LGA infant and the maternal risk of diabetes: A prospective cohort study Primary care diabetes 12 4: 364-370. 2018

Antikainen, Leena; Jääskeläinen, Jarmo; Nordman, Henrikki; Voutilainen, Raimo; Huopio, Hanna. 2018. Prepubertal Children Exposed to Maternal Gestational Diabetes Have Latent Low-Grade Inflammation HORMONE RESEARCH IN PAEDIATRICS 90 2: 109-115. 2018

Liimatta Jani, Utriainen Pauliina, Voutilainen Raimo, Jääskeläinen Jarmo. 2017. Girls with a History of Premature Adrenarche Have Advanced Growth and Pubertal Development at the Age of 12 Years. FRONTIERS IN ENDOCRINOLOGY 8: 291. 2017

Mäntyselkä A, Jääskeläinen J, Eloranta AM, Väistö J, Voutilainen R, Ong K, Brage S, Lakka TA, Lindi V. 2017. Associations of lifestyle factors with serum dehydroepiandrosterone sulfate and insulin-like growth factor-1 concentration in prepubertal children Clinical endocrinology 2018; 88 2: 234-242. 2017

Nordman Henrikki, Voutilainen Raimo, Antikainen Leena, Jääskeläinen Jarmo. 2017. Prepubertal children born large for gestational age have lower serum DHEAS concentrations than those with a lower birth weight. PEDIATRIC RESEARCH 82 2: 285-289. 2017

Demir A, Voutilainen R, Stenman UH, Dunkel L, Albertsson-Wikland K, Norjavaara E. 2016. First Morning Voided Urinary Gonadotropin Measurements as an Alternative to the GnRH Test. HORMONE RESEARCH IN PAEDIATRICS 85 5: 301-308. 2016

Hakkarainen H, Huopio H, Cederberg H, Pääkkönen M, Voutilainen R, Heinonen S. 2016. The risk of metabolic syndrome in women with previous GDM in a long-term follow-up. GYNECOLOGICAL ENDOCRINOLOGY 32 11: 920-925. 2016

Lehikoinen Anni, Ordén Maija-Riitta, Heinonen Seppo, Voutilainen Raimo. 2016. Maternal drug or alcohol abuse is associated with decreased head size from mid-pregnancy to childhood. ACTA PAEDIATRICA 105 7: 817-822. 2016

Tenhola Sirpa, Voutilainen Raimo, Reyes Monica, Toiviainen-Salo Sanna, Jüppner Harald, Mäkitie Outi. 2016. Impaired growth and intracranial calcifications in autosomal dominant hypocalcemia caused by a GNA11 mutation. EUROPEAN JOURNAL OF ENDOCRINOLOGY 175 3: 211-218. 2016

Utriainen P, Laakso S, Liimatta J, Jääskeläinen J, Voutilainen R. 2015. Premature Adrenarche - A Common Condition with Variable Presentation HORMONE RESEARCH IN PAEDIATRICS 83 4: 221-231. 2015

Seppä Satu, Voutilainen Raimo, Tenhola Sirpa. 2015. Markers of Insulin Sensitivity in 12-Year-Old Children Born from Preeclamptic Pregnancies. JOURNAL OF PEDIATRICS epub ahead of print 9 May 2015. 2015

Hakkarainen Heidi, Huopio Hanna, Cederberg Henna, Pääkkönen Mirja, Voutilainen Raimo, Heinonen Seppo. 2015. Post-challenge glycemia during pregnancy as a marker of future risk of type 2 diabetes: a prospective cohort study. GYNECOLOGICAL ENDOCRINOLOGY 31 7: 573-577. 2015

Nordman H, Voutilainen R, Laitinen T, Antikainen L, Huopio H, Heinonen S, Jääskeläinen J. 2015. Growth and Cardiovascular Risk Factors in Prepubertal Children Born Large or Small for Gestational Age. HORMONE RESEARCH IN PAEDIATRICS 2016; 85 1: 11-17. 2015

Huopio Hanna, Hakkarainen Heidi, Pääkkönen Mirja, Kuulasmaa Teemu, Voutilainen Raimo, Heinonen Seppo, Cederberg Henna. 2014. Long-term changes in glucose metabolism after gestational diabetes: a double cohort study. BMC PREGNANCY AND CHILDBIRTH 14: 296. 2014

Liimatta Jani, Laakso Saila, Utriainen Pauliina, Voutilainen Raimo, Palvimo Jorma J, Jääskeläinen Tiina, Jääskeläinen Jarmo. 2014. Serum androgen bioactivity is low in children with premature adrenarche. PEDIATRIC RESEARCH 75 5: 645-650. 2014

Mäntyselkä Aino, Jääskeläinen Jarmo, Lindi Virpi, Viitasalo Anna, Tompuri Tuomo, Voutilainen Raimo, Lakka Timo A. 2014. Ennenaikaisen adrenarken sukupuolierot saattavat johtua erilaisesta kehon rasvakoostumuksesta. DUODECIM 130: 101. 2014

Mäntyselkä Aino, Jääskeläinen Jarmo, Lindi Virpi, Viitasalo Anna, Tompuri Tuomo, Voutilainen Raimo, Lakka Timo A. 2014. The presentation of adrenarche is sexually dimorphic and modified by body adiposity. JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM 99 10: 3889-3894. 2014

Voutilainen Raimo, Jääskeläinen Jarmo. 2014. Premature adrenarche: Etiology, clinical findings, and consequences. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY 2014: SBMB 4213 No. of Pages 11. 2014

Jääskeläinen, J; Voutilainen, R. 2012. Lisämunuaiskuoren vajaatoiminta: Korppi, M; Kröger, L; Rantala, H, Lastentautien päivystyskirja, 2. painos.Kustannus Oy Duodecim. 183-186. 2012

Todorova B, Salonen M, Jääskeläinen J, Tapio A, Jääskeläinen T, Palvimo J, Turpeinen U, Hämäläinen E, Räsänen M, Tenhola S, Voutilainen R. 2012. Adrenocortical hormonal activity in 20-year-old subjects born small or appropriate for gestational age. HORMONE RESEARCH IN PAEDIATRICS 77: 294-304. 2012

Utriainen, P; Jääskeläinen, J; Voutilainen, R. 2012. Blood Erythrocyte and Hemoglobin Concentrations in Premature Adrenarche. JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM 97 11: E1-5. 2012

Utriainen, P; Laakso, S; Jääskeläinen, J; Voutilainen, R. 2012. Polymorphisms of POR, SULT2A1 and HSD11B1 in children with premature adrenarche. METABOLISM 61 9: 1215-1219. 2012

Voutilainen, R; Tenhola, S. 2012. Catch-Up Growth and Corticosteroids: A Focus on Mechanisms and Clinical Conditions. In: Victor R. Preedy (ed.) , Handbook of Growth and Growth Monitoring in Health and Disease, printed in 3 volumes.Springer. ss. 893-904. 2012

Tkachenko Irina V, Jääskeläinen Tiina, Jääskeläinen Jarmo, Palvimo Jorma J, Voutilainen Raimo. 2011. Interleukins 1alfa and 1 beta as regulators of steroidogenesis in human NCI-H295R adrenocortical cells. STEROIDS (NEW YORK NY) 76: 1103-1115. 2011

Voutilainen, R. 2011. ESPE from a Personal and Finnish Perspective: Sippell WG, Sippell WG (ed): ESPE - The First 50 Years. A History of the European Society for Paediatric Endocrinology.S.Karger AG. 122-125. 2011

Utriainen P, Jääskeläinen J & Voutilainen R. 2010. Ennenaikainen adrenarke. Mitä tehdä, kun lapsen hiki haisee? SUOMEN LÄÄKÄRILEHTI 65 47: 3875-3881. 2010

Utriainen P, Jääskeläinen J & Voutilainen R. 2010. Serum Anti-Müllerian Hormone Concentrations in Prepubertal Girls with and without Premature Adrenarche: The Influence Of Body Mass Index HORMONE RESEARCH IN PAEDIATRICS 74: 207-211. 2010

Utriainen P, Jääskeläinen J, Gröhn O, Kuusisto J, Pulkki K & Voutilainen R. 2010. Circulating TNF-alpha and IL-6 concentrations and TNF-alpha-308 G > A polymorphism in children with premature adrenarche FRONTIERS IN ENDOCRINOLOGY 1: doi: 10.3389/fendo.2010.00006, Article 6: 1-6. 2010

Salonen M, Tenhola S, Laitinen T, Lyyra-Laitinen T, Romppanen J, Jääskeläinen J & Voutilainen R. 2010. Tracking Serum Lipid Levels and the Association of Cholesterol Concentrations, Blood Pressure and Cigarette Smoking With Carotid Artery Intima-Media Thickness in Young Adults Born Small for Gestational Age. CIRCULATION JOURNAL 74: 2419-2425. 2010

Nykänen P, Heinonen K, Riepe FG, Sippell WG & Voutilainen R. 2010. Serum Concentrations of Adrenal Steroids and Their Precursors as a Measure of Maturity of Adrenocortical Function in Very Premature Newborn. HORMONE RESEARCH IN PAEDIATRICS 74: 358-364. 2010

Laakso S, Utriainen P, Laakso M, Voutilainen R & Jääskeläinen J. 2010. Polymorphism Pro12Ala of PPARG in Prepubertal Children with Premature Adrenarche and Its Association with Growth in Healthy Children. HORMONE RESEARCH IN PAEDIATRICS 74: 365-371. 2010

S Tenhola, B Todorova, J Jääskeläinen, OA Jänne, T Raivio & R Voutilainen. 2010. Serum glucocorticoids and adiponectin associate with insulin resistance in children born small for gestational age. EUROPEAN JOURNAL OF ENDOCRINOLOGY 162 3: 551-557. 2010

Jääskeläinen J, Voutilainen R. 2009. Lisämunuaiskuoren vajaatoiminta: Korppi M, Kröger L, Rantala H, Lastentautien päivystyskirja. 1. p..Duodecim. 156-159. 2009

Lappalainen S, Saarinen A, Utriainen P, Voutilainen R, Jääskeläinen J, Mäkitie O. 2009. LRP5 in premature adrenarche and metabolic characteristics of prepubertal children CLINICAL ENDOCRINOLOGY 70: 725-731. 2009

Liu J, Bützow R, Hydén-Granskog C, Voutilainen R. 2009. Expression of adrenomedullin in human ovaries, ovarian sex cord-stromal tumors and cultured granulosa-luteal cells. GYNECOLOGICAL ENDOCRINOLOGY 25 2: 96-103. 2009

Utriainen P, Jääskeläinen J, Saarinen A, Vanninen E, Mäkitie O, Voutilainen R. 2009. Body composition and bone mineral density in children with premature adrenarche and the association of LRP5 gene polymorphisms with bone mineral density. JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM 94 11: 4144-4151. 2009

Utriainen P, Voutilainen R, Jääskeläinen J. 2009. Continuum of phenotypes and sympathoadrenal function in premature adrenarche. EUROPEAN JOURNAL OF ENDOCRINOLOGY 160: 657-665. 2009

Utriainen P, Voutilainen R, Jääskeläinen J. 2009. Girls with premature adrenarche have accelerated early childhood growth. JOURNAL OF PEDIATRICS 154: 882-887. 2009

Lappalainen S, Utriainen P, Kuulasmaa T, Voutilainen R, Jääskeläinen J. 2008. Androgen receptor gene CAG repeat polymorphism and X-chromosome inactivation in children with premature adrenarche JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM 93 4: 1304-1309. 2008

Mikhaylova IV, Jääskeläinen T, Jääskeläinen J, Palvimo JJ, Voutilainen R. 2008. Leukemia inhibitory factor as a regulator of steroidogenesis in human NCI-H295R adrenocortical cells JOURNAL OF ENDOCRINOLOGY 199: 435-444. 2008

Kuulasmaa T, Jääskeläinen J, Suppola S, Pietiläinen T, Heikkilä P, Aaltomaa S, Kosma V-M, Voutilainen R. 2008. WNT-4 mRNA expression in human adrenocortical tumors and cultured adrenal cells HORMONE AND METABOLIC RESEARCH 40: 668-673. 2008

Lappalainen S, Utriainen P, Kuulasmaa T, Voutilainen R, Jääskeläinen J. 2008. ACTH receptor promoter polymorphism associates with severity of premature adrenarche and modulates hypothalamo-pituitary-adrenal axis in children. PEDIATRIC RESEARCH 63 4: 410-414. 2008

Jääskeläinen J, Korhonen S, Kuulasmaa T, Kurl S, Niskanen L, Vanhala M, Hippeläinen M, Voutilainen R, Heinonen S. 2008. Androgen receptor gene CAG repeat length in women with metabolic syndrome. GYNECOLOGICAL ENDOCRINOLOGY 24 7: 411-416. 2008

Mikhaylova IV, Kuulasmaa T, Jääskeläinen J, Voutilainen R. 2007. Tumor necrosis factor-alfa regulates steroidogenesis, apoptosis, and cell viability in the human adrenocortical cell line NCI-H295R. ENDOCRINOLOGY 148 1: 386-392. 2007

Nykänen P, Anttila E, Heinonen K, Hallman M, Voutilainen R. 2007. Early hypoadrenalism in premature infants at risk for bronchopulmonary dysplasia or death. ACTA PAEDIATRICA 96: 1600-1605. 2007

Nykänen P, Raivio T, Heinonen K, Jänne OA, Voutilainen R. 2007. Circulating glucocorticoid bioactivity and serum cortisol concentrations in premature infants: the influence of exogenous glucocorticoids and clinical factors EUROPEAN JOURNAL OF ENDOCRINOLOGY 156: 577-583. 2007

Utriainen P, Jääskeläinen J, Romppanen J, Voutilainen R. 2007. Childhood metabolic syndrome and its components in premature adrenarche. JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM 92 11: 4282-4285. 2007

Tenhola S, Rahiala E, Halonen P, Vanninen E, Voutilainen R. 2006. Maternal preeclampsia predicts elevated blood pressure in 12-year-old children: Evaluation by ambulatory blood pressure monitoring. PEDIATRIC RESEARCH 59 2: 320-324. 2006

Utriainen P, Liu J, Kuulasmaa T, Voutilainen R. 2006. Inhibition of DNA methylation increases follistatin expression and secretion in the human adrenocortical cell line NCI-H295R. JOURNAL OF ENDOCRINOLOGY 188: 305-310. 2006

Tenhola S, Turpeinen U, Halonen P, Hämäläinen E, Voutilainen R. 2005. Association of serum lipid concentrations, insulin resistance index and catch-up growth with serum cortisol/cortisone ratio by liquid chromatography tandem mass spectrometry in children born small for gestational age. PEDIATRIC RESEARCH 58 3: 467-471. 2005

Tenhola S, Halonen P, Jääskeläinen J, Voutilainen R. 2005. Serum markers of GH and insulin action in 12-year-old children born small for gestational age. EUROPEAN JOURNAL OF ENDOCRINOLOGY 125: 335-340. 2005

Peltoniemi O, Kari A, Heinonen K, Saarela T, Nikolajev K, Andersson S, Voutilainen R, Hallman M. 2005. Pretreatment cortisol values may predict responses to hydrocortisone administration for the prevention of bronchopulmonary dysplasia in high-risk infants. JOURNAL OF PEDIATRICS 146 6: 632-637. 2005

Saarela T, Jääskeläinen J, Tenhola S, Voutilainen R, Heinonen S. 2005. Preeclampsia and androgen receptor gene CAG repeat length: results from both children and women. JOURNAL OF ASSISTED REPRODUCTION AND GENETICS 22 7: 269-275. 2005

Jääskeläinen J, Korhonen S, Voutilainen R, Hippeläinen M, Heinonen S. 2005. Androgen receptor gene CAG length polymorphism in women with polycystic ovary syndrome. FERTILITY AND STERILITY 83 6: 1724-1728. 2005

Kiiveri S, Liu J, Arola J, Heikkilä P, Kuulasmaa T, Lehtonen E, Voutilainen R, Heikinheimo M. 2005. Transcription factors GATA-6, SF-1, and cell proliferation in human adrenocortical tumors. MOLECULAR AND CELLULAR ENDOCRINOLOGY 233: 47-56. 2005

Astuti D, Morris M, Krona C, Abel F, Gentle D, Martinsson T, Kogner P, Neumann HPH, Voutilainen R, Eng C, Rustin P, Latif F, Maher ER. 2004. Investigation of the role of SDHB inactivation in sporadic phaeochromocytoma and neuroblastoma BRITISH JOURNAL OF CANCER 91: 1835-1841. 2004

Kannisto S, Laatikainen A, Taivainen A, Savolainen K, Tukiainen H, Voutilainen R. 2004. Serum dehydroepiandrosterone sulfate concentration as an indicator of adrenocortical suppression during inhaled steroid therapy in adult asthmatic patients EUROPEAN JOURNAL OF ENDOCRINOLOGY 150: 687-690. 2004

Kiiveri S, Liu J, Heikkilä P, Arola J, Lehtonen E, Voutilainen R, Heikinheimo M. 2004. Transcription factors GATA-4 and GATA-6 human adrenocortical tumors. ENDOCRINE RESEARCH 30 4: 919-923. 2004

Liu J, Li X-D, Ora A, Heikkilä P, Vaheri A, Voutilainen R. 2004. cAMP-dependent protein kinase activation inhibits proliferation and enhances apoptotic effect of tumor necrosis factor-alfa in NCI-H295R adrenocortical cells. JOURNAL OF MOLECULAR ENDOCRINOLOGY 33: 511-522. 2004

Liu J, Li X-D, Vaheri A, Voutilainen R. 2004. DNA methylation affects cell proliferation, cortisol secretion and steroidogenic gene expression in human adrenocortical NCI-H295R cells. JOURNAL OF MOLECULAR ENDOCRINOLOGY 33: 651-662. 2004

Vänttinen T, Liu J, Kuulasmaa T, Kivinen P, Voutilainen R. 2003. Expression of activin/inhibin signaling components in the human adrenal gland and the effects of activins and inhibins on adrenocortical steroidogenesis and apoptosis. JOURNAL OF ENDOCRINOLOGY 178: 479-489. 2003

Arikoski P, Voutilainen R, Kröger H, Kröger H. 2003. Bone mineral density in long-term survivors of childhood cancer. JOURNAL OF PEDIATRIC ENDOCRINOLOGY AND METABOLISM 16: 343-353. 2003

Tenhola S, Rahiala E, Martikainen A, Halonen P, Voutilainen R. 2003. Blood pressure, serum lipids, fasting insulin, and adrenal hormones in 12-year-old children born with maternal preeclampsia. JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM 88 3: 1217-1222. 2003

Liu J, Kuulasmaa T, Kosma V-M, Bützow R, Vänttinen T, Hydén-Granskog C, Voutilainen R. 2003. Expression of betaglycan, an inhibin coreceptor, in normal human ovaries and ovarian sex cord-stromal tumors and its regulation in cultured human granulosa-luteal cells. JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM 88 10: 5002-5008. 2003

Liu J, Vänttinen T, Hyden-Granskog C, Voutilainen R. 2002. Regulation of follistatin-related gene (FLRG) expression by protein kinase C and prostaglandin E2 in cultured granulosa-luteal cells. MOLECULAR HUMAN REPRODUCTION 8 11: 992-997. 2002

Vänttinen T, Liu J, Hyden-Granskog C, Voutilainen R. 2002. Biphasic regulation of activin A secretion by gonadotropins in cultured human ovarian granulosa-luteal cells leads to decreasing activin: inhibin ratios during continuing gonadotropin stimulation. JOURNAL OF ENDOCRINOLOGY 172: 557-563. 2002

Vänttinen T, Kuulasmaa T, Liu J, Voutilainen R. 2002. Expression of activin/inhibin receptor and binding protein genes and regulation of activin/inhibin peptide secretion in human adrenocortical cells. JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM 87 9: 4257-4263. 2002

Tenhola S, Martikainen A, Rahiala E, Parviainen M, Halonen P, Voutilainen R. 2002. Increased adrenocortical and adrenomedullary hormonal activity in 12-year-old children born small for gestational age. JOURNAL OF PEDIATRICS 141: 477-482. 2002

Raivio T, Palvimo JJ, Kannisto S, Voutilainen R, Jänne OA. 2002. Transactivation assay for determination of glucocorticoid bioactivity in human serum. JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM 87 8: 3740-3744. 2002

Kiiveri S, Liu J, Westerholm-Ormio M, Narita N, Wilson DB, Voutilainen R, Heikinheimo M. 2002. Differential expression of GATA-4 and GATA-6 in fetal and adult mouse and human adrenal tissue. ENDOCRINOLOGY 143 8: 3136-3143. 2002

Liu J, Kosma V-M, Vänttinen T, Hyden-Granskog C, Voutilainen R. 2002. Gonadotrophins inhibit the expression of insulin-like growth factor binding protein-related protein-2 mRNA in cultured human granulosa-luteal cells. MOLECULAR HUMAN REPRODUCTION 8 2: 136-141. 2002

Kannisto S, Voutilainen R, Remes K, Korppi M. 2002. Efficacy and safety of inhaled steroid and cromone treatment in school-age children: A randomized pragmatic pilot study. PEDIATRIC ALLERGY AND IMMUNOLOGY 13: 24-30. 2002

Kannisto S, Korppi M, Arikoski P, Remes K, Voutilainen R. 2002. Biochemical markers of bone metabolism in relation to adrenocortical and growth suppression during the initiation phase of inhaled steroid therapy. PEDIATRIC RESEARCH 52 2: 258-262. 2002

Huopio H, Jääskeläinen J, Komulainen J, Miettinen R, Kärkkäinen P, Laakso M, Tapanainen P, Voutilainen R, Otonkoski T. 2002. Acute insulin response tests for the differential diagnosis of congenital hyperinsulinism. JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM 87: 4502-4507. 2002

Gao Z-H, Suppola S, Liu J, Heikkilä P, Jänne J, Voutilainen R. 2002. Association of H19 promoter methylation with the expression of H19 and IGF-II genes in adrenocortical tumors. JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM 87 3: 1170-1176. 2002

Arikoski P, Komulainen J, Voutilainen R, Kröger L, Kröger H. 2002. Lumbar bone mineral density in normal subjects aged 3-6 years: a prospective study. ACTA PAEDIATRICA 91: 287-291. 2002

Astuti D, Agathanggelou A, Honorio S, Dallol A, Martinsson T, Kogner P, Cummins C, Neumann HPH, Voutilainen R, Dahia P, Eng C, Maher ER, Latif F. 2001. RASSF1A promoter region CpG island hypermethylation in phaeochromocytomas and neuroblastoma tumours. ONCOGENE (LONDON) 20: 7573-7577. 2001

Jääskeläinen J, Tiitinen A, Voutilainen R. 2001. Sexual function and fertility in adult females and males with congenital adrenal hyperplasia. HORMONE RESEARCH 56: 73-80. 2001

Kannisto S, Korppi M, Remes K, Voutilainen R. 2001. Serum dehydroepiandrosterone sulfate concentration as an indicator of adrenocortical suppression in asthmatic children treated with inhaled steroids JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM 86 10: 4908-4912. 2001

Liu J, Hydén-Granskog C, Voutilainen R. 2001. Gonadotrophins inhibit and activin induces expression of inhibin /activin beta-B subunit mRNA in cultured human granulosa-luteal cells. MOLECULAR HUMAN REPRODUCTION 7 4: 319-323. 2001

Salmenkivi K, Arola J, Voutilainen R, Ilvesmäki V, Haglund C, Kahri AI, Heikkilä P, Liu J. 2001. Inhibin/activin beta-B-subunit expression in pheochromocytomas favors benign diagnosis JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM 86 5: 2231-2235. 2001

Välimäki MJ, Voutilainen R, Kaitila I, Tuomi T. 2001. Lasten riisitaudista aikuisten osteomalasiaan. DUODECIM 117: 2171-2180. 2001

Liu J, Heikkilä P, Kahri AI, Voutilainen R. 2000. Expression of activin A and its receptors in human pheochromocytomas JOURNAL OF ENDOCRINOLOGY 165: 503-508. 2000

Tenhola S, Martikainen A, Rahiala E, Herrgård E, Halonen P, Voutilainen R. 2000. Serum lipid concentrations and growth characteristics in 12-year-old children born small for gestational age. PEDIATRIC RESEARCH 48 5: 623-628. 2000

Nykänen P, Heinonen K, Voutilainen R. 2000. Comparison between low- and standard-dose ACTH tests in premature infants at risk for chronic lung disease. HORMONE RESEARCH (1999)52: 274-278. 2000

Liu J, Heikkilä P, Meng Q-H, Kahri AI, Tikkanen MJ, Voutilainen R. 2000. Expression of low and high density lipoprotein receptor genes in human adrenals EUROPEAN JOURNAL OF ENDOCRINOLOGY 142: 677-682. 2000

Vänttinen T, Liu J, Hyden-Granskog C, Parviainen M, Penttilä I, Voutilainen R. 2000. Regulation of immunoreactive inhibin A and B secretion in cultured human granulosa-luteal cells by gonadotropins, activin A and insulin-like growth factor type-1 receptor. JOURNAL OF ENDOCRINOLOGY 167 2: 289-294. 2000

Kannisto S, Korppi M, Remes K, Voutilainen R. 2000. Adrenal suppression, evaluated by a low dose adrenocorticotropin test, and growth in asthmatic children treated with inhale steroids JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM 85 2: 652-657. 2000

Jääskeläinen J, Voutilainen R. 2000. Long-term outcome of classical 21-hydroxylase deficiency: diagnosis, complications and quality of life. ACTA PAEDIATRICA 89: 183-187. 2000

Jääskeläinen J, Kiekara O, Hippeläinen M, Voutilainen R. 2000. Pituitary gonadal axis and child rate in males with classical 21-hydroxylase deficiency. JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION (MILANO) 23: 23-27. 2000

Jääskeläinen J, Hippeläinen M, Kiekara O, Voutilainen R. 2000. Child rate, pregnancy outcome and ovarian function in females with classical 21-hydroxylase deficiency ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA 79: 687-692. 2000

Arola J, Liu J, Heikkilä P, Ilvesmäki V, Salmenkivi K, Voutilainen R, Kahri AI. 2000. Expression of inhibin alpha in adrenocortical tumours reflects the hormonal status of the neoplasm JOURNAL OF ENDOCRINOLOGY 165: 223-229. 2000

Liu J, Voutilainen R, Heikkilä P, Kahri AI. 1999. pG2 gene expression and its regulation in human adrenocortical and medullary tumors. EUROPEAN JOURNAL OF ENDOCRINOLOGY 140: 590-596. 1999

Liu J, Kahri AI, Heikkilä P, Voutilainen R. 1999. Regulation of neuropeptide Y mRNA expression in cultured human pheochromocytoma cells. EUROPEAN JOURNAL OF ENDOCRINOLOGY 141: 431-435. 1999

Levo A, Jääskeläinen J, Sistonen P, Sirén M-K, Voutilainen R, Partanen J. 1999. Tracing past population migrations: genealogy of steroid 21-hydroxylase (CYP21) gene mutations in Finland EUROPEAN JOURNAL OF HUMAN GENETICS 7: 188-196. 1999

Jääskeläinen J, Voutilainen R. 1999. Lisämunuaiskuoren vajaatoiminta: Jääskeläinen J, Herrgård E, Komulainen J, Tikanoja T, Korppi M, Lastenlääkärin päivystyskirja.KYS, lastenklinikka. 107-109. 1999

Heikinheimo AK, Laine MA, Ritvos OV-P, Voutilainen RJ, Hogan BLM, Leivo IV. 1999. Bone morphogenetic protein-6 is a marker of serous acinar cell differentiation in normal and neoplastic human salivary gland. CANCER RESEARCH 59: 5815-5821. 1999

Arikoski P, Kröger H, Riikonen P, Parviainen M, Voutilainen R, Komulainen J. 1999. Disturbance in bone turnover in children with a malignancy at completion of chemotherapy. PEDIATRIC BLOOD AND CANCER 33: 455-461. 1999

Arikoski P, Komulainen J, Riikonen P, Voutilainen R, Knip M, Kröger H. 1999. Alterations in bone turnover and impaired development of bone mineral density in newly diagnosed children with cancer: a 1-year prospective study. JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM 84: 3174-3181. 1999

Arikoski P, Komulainen J, Riikonen P, Parviainen M, Jurvelin JS, Voutilainen R, Kröger H. 1999. Impaired development of bone mineral density during chemotherapy: a prospective analysis of 46 children newly diagnosed with cancer. JOURNAL OF BONE AND MINERAL RESEARCH 14 12: 2002-2009. 1999

Arikoski P, Komulainen J, Riikonen P, Jurvelin JS, Voutilainen R, Kröger H. 1999. Reduced bone density at completion of chemotherapy for a malignancy. ARCHIVES OF DISEASE IN CHILDHOOD 80: 143-148. 1999

Arikoski P, Komulainen J, Voutilainen R, Riikonen P, Parviainen M, Tapanainen P, Knip M, Kröger H. 1998. Reduced bone mineral density in long-term survivors of childhood acute lymphoblastic leukemia. JOURNAL OF PEDIATRIC HEMATOLOGY/ONCOLOGY 20 3: 234-240. 1998

Ilvesmäki V, Liu J, Heikkilä P, Kahri AI, Voutilainen R. 1998. Expression of insulin-like growth factor binding protein 1-6 genes in adrenocortical tumors and pheochromocytomas. HORMONE AND METABOLIC RESEARCH 30 10: 619-623. 1998

Martikainen A, Voutilainen R. 1998. Miten opettaja voi parantaa opetustaan - esimerkki lastentautien perusopetuksesta. DUODECIM 114: 2174-2180. 1998

Voutilainen R. 1998. Adrenocortical cells are the site of secretion and action of insulin-like growth factors and TNF-alpha. HORMONE AND METABOLIC RESEARCH 30 6/7: 432-435. 1998

Woodward ER, Eng C, McMahon R, Voutilainen R, Affara NA, Ponder BAJ, Maher ER. 1997. Genetic predisposition to phaeochromocytoma: analysis of candidate genes GDNF, RET and VHL. HUMAN MOLECULAR GENETICS 6 7: 1051-1056. 1997

Liu J, Voutilainen R, Kahri AI, Heikkilä P. 1997. Expression patterns of the c-myc gene in adrenocortical tumors and pheochromocytomas. JOURNAL OF ENDOCRINOLOGY 152: 175-181. 1997

Liu J, Voutilainen R, Heikkilä P, Kahri AI. 1997. Ribonucleic acid expression of the CLA-1 gene, a human homolog to mouse high density lipoprotein receptor SR-BI, in human adrenal tumors and cultured adrenal cells. JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM 82 8: 2522-2527. 1997

Liu J, Kahri AI, Heikkilä P, Voutilainen R. 1997. Adrenomedullin gene expression and its different regulation in human adrenocortical and medullary tumors JOURNAL OF ENDOCRINOLOGY 155: 483-490. 1997

Liu J, Kahri AI, Heikkilä P, Voutilainen R. 1997. Ribonucleic acid expression of the clustered imprinted genes, p57KIP2, insulin-like growth factor II, and H19, in adrenal tumors and cultured adrenal cells. JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM 82: 1766-1771. 1997

Jääskeläinen J, Levo A, Voutilainen R, Partanen J. 1997. Population-wide evaluation of disease manifestation in relation to molecular genotype in steroid 21-hydroxylase (CYP21) deficiency: Good correlation in a well defined population. JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM 82 10: 3293-3297. 1997

Ariel I, Weinstein D, Voutilainen R, Schneider T, Lustig-Yariv O, de Groot N, Hochenberg A. 1997. Genomic imprinting and the endometrial cycle. The expression of the imprinted gene H19 in the human female reproductive organs. DIAGNOSTIC MOLECULAR PATHOLOGY (NEW YORK NY) 6 1: 17-25. 1997

Jääskeläinen J, Voutilainen R. 1997. Growth of patients with 21-Hydroxylase deficiency: An analysis of the factors influencing adult height PEDIATRIC RESEARCH 41 1: 30-33. 1997

Liu J, Heikkilä P, Kahri AI, Voutilainen R. 1996. Expression of the steroidogenic acute regulatory protein mRNA in adrenal tumors and cultured adrenal cells. JOURNAL OF ENDOCRINOLOGY 150: 43-50. 1996

XXII Spring Meeting of The Finnish Endocrine Society. Kuopio, Finland 10.-11.5.1996. Program and Abstracts. Niskanen L, Voutilainen R. 1996 1996

Liu J, Voutilainen R, Kahri AI, Heikkilä P. 1996. Expression of the c-myc gene in human adrenals: regulation by adrenocorticotropin in primary cultures. JOURNAL OF ENDOCRINOLOGY 148: 523-529. 1996

Voutilainen R, Franks S, Mason HD, Martikainen H. 1996. Expression of insulin-like growth factor (IGF), IGF-binding protein, and IGF receptor messenger ribonucleic acids in normal and polycystic ovaries. JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM 81 3: 1003-1008. 1996

Kari MA, Raivio KO, Stenman U-H, Voutilainen R. 1996. Serum cortisol, dehydroepiandrosterone sulfate, and steroid-binding globulins in preterm neonates: effect of gestational age and dexamethasone therapy. PEDIATRIC RESEARCH 40 2: 319-324. 1996

Jääskeläinen J, Voutilainen R. 1996. Bone mineral density in relation to glucocorticoid substitution therapy in adult patients with 21-hydroxylase deficiency. CLINICAL ENDOCRINOLOGY 45: 707-713. 1996

Jääskeläinen J, Partanen J, Hippeläinen M, Levo A, Voutilainen R. 1996. 21-hydroksylaasivajeen sikiökautinen diagnostiikka ja deksametasonihoito. DUODECIM 112: 1258-1263. 1996

Demir A, Voutilainen R, Juul A, Dunkel L, Alfthan H, Skakkebaek NE, Stenman U-H. 1996. Increase in first morning voided urinary luteinizing hormone levels precedes the physical onset of puberty. JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM 81 8: 2963-2967. 1996

Demir A, Dunkel L, Stenman U-H, Voutilainen R. 1995. Age-related course of urinary gonadotropins in children. JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM 80 4: 1457-1460. 1995

Komulainen J, Pietikäinen M, Kalavainen M, Voutilainen R. 1995. Lapsuusiän lihavuuden hoidon järjestäminen SUOMEN LÄÄKÄRILEHTI 50 12: 1440-1441. 1995

Koskinen T, Pihko H, Voutilainen R. 1995. Primary hypogonadism in females with infantile onset spinocerebellar ataxia. NEUROPEDIATRICS 26: 263-266. 1995

Laatikainen TJ, Tomás EI, Voutilainen RJ. 1995. The expression of insulin-like growth factor and its protein mRNA in the endometrium of postmenopausal patients with breast cancer receiving tamoxifen. CANCER 76 8: 1406-1410. 1995

Liu J, Kahri AI, Heikkilä P, Ilvesmäki V, Voutilainen R. 1995. H19 and insulin-like growth factor-II gene expression in adrenal tumors and cultured adrenal cells. JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM 80 2: 492-496. 1995

Pere A, Perheentupa J, Peter M, Voutilainen R. 1995. Follow up of growth and steroids in premature adrenarche. EUROPEAN JOURNAL OF PEDIATRICS 154: 346-352. 1995

Voutilainen R. 1995. What is the function of adrenal inhibins?. EUROPEAN JOURNAL OF ENDOCRINOLOGY 132: 290-291. 1995

Ilvesmäki V, Voutilainen R. 1994. Kasvutekijät ja sytokiinit hormonivaikutusten välittäjinä. DUODECIM 110: 949-957. 1994

Niskanen L, Voutilainen R, Teräsvirta M, Lehtinen J, Teppo AM, Groop L, Uusitupa M. 1993. A prospective study on clinical and metabolic associates of proteinuria in patients with type 2 diabetes mellitus. DIABETIC MEDICINE 10: 543-549. 1993

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