Ruth Stephen

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My research interests are the prevention of Alzheimer’s disease and dementia with a special focus on dementia risk scores, biomarkers and interventions.

Research groups

Keywords

CAIDE clinical research clinical trials dementia MRI multimodal interventions neurology prevention public health risk factors

Publications

18/18 items

The Australian National University Alzheimer's Disease Risk Index (ANU‐ADRI) score as a predictor for cognitive decline and potential surrogate outcome in the FINGER lifestyle randomized controlled trial
Hall, Anette; Barbera, Mariagnese; Lehtisalo, Jenni; Antikainen, Riitta; Huque, Hamidul; Laatikainen, Tiina; Ngandu, Tiia; Soininen, Hilkka; Stephen, Ruth; Strandberg, Timo; Kivipelto, Miia; Anstey, Kaarin J; Solomon, Alina. 2024. European journal of neurology. [Epub ahead of print 7 Feb 2024]:
Association of tooth count with cognitive decline and dementia in the Finnish adult population
Asher, Sam; Suominen, Anna Liisa; Stephen, Ruth; Ngandu, Tiia; Koskinen, Seppo; Solomon, Alina. 2023. Journal of clinical periodontology. 50: 1154-1166
Dementia prevention in memory clinics: recommendations from the European task force for brain health services
Frisoni, Giovanni B.; Altomare, Daniele; Ribaldi, Federica; Villain, Nicolas; Brayne, Carol; Mukadam, Naaheed; Abramowicz, Marc; Barkhof, Frederik; Berthier, Marcelo; Bieler-Aeschlimann, Melanie; Blennow, Kaj; Brioschi Guevara, Andrea; Carrera, Emmanuel; Chételat, Gaël; Csajka, Chantal; Demonet, Jean-François; Dodich, Alessandra; Garibotto, Valentina; Georges, Jean; Hurst, Samia; Jessen, Frank; Kivipelto, Miia; Llewellyn, David J.; McWhirter, Laura; Milne, Richard; Minguillón, Carolina; Miniussi. 2023. The Lancet regional health – Europe. 26:
The role of brain integrity in the association between occupational complexity and cognitive performance in subjects with increased risk of dementia
Rydstrom, Anders; Stephen, Ruth; Kareholt, Ingemar; Mattsson, Alexander Darin; Ngandu, Tiia; Lehtisalo, Jenni; Backman, Lars; Kemppainen, Nina; Rinne, Juha; Sindi, Shireen; Soininen, Hilkka; Vanninen, Ritva; Solomon, Alina; Mangialasche, Francesca. 2023. Gerontology. 69: 972-985
Dementia Risk Scores and Their Role in the Implementation of Risk Reduction Guidelines
Anstey, Kaarin J; Zheng, Lidan; Peters, Ruth; Kootar, Scherazad; Barbera, Mariagnese; Stephen, Ruth; Dua, Tarun; Chowdhary, Neerja; Solomon, Alina; Kivipelto, Miia. 2022. Frontiers in neurology. 12: . 765454
Periodontal health, cognitive decline, and dementia: A systematic review and meta‐analysis of longitudinal studies
Asher, Sam; Stephen, Ruth; Mäntylä, Päivi; Suominen, Anna Liisa; Solomon, Alina. 2022. Journal of the american geriatrics society. 70: 2695-2709
Reducing the Risk of Cognitive Decline and Dementia: WHO Recommendations
Chowdhary, Neerja; Barbui, Corrado; Anstey, Kaarin J.; Kivipelto, Miia; Barbera, Mariagnese; Peters, Ruth; Zheng, Lidan; Kulmala, Jenni; Stephen, Ruth; Ferri, Cleusa P.; Joanette, Yves; Wang, Huali; Comas-Herrera, Adelina; Alessi, Charles; Suharya (Dy), Kusumadewi; Mwangi, Kibachio J.; Petersen, Ronald C.; Motala, Ayesha A.; Mendis, Shanthi; Prabhakaran, Dorairaj; Bibi Mia Sorefan, Ameenah; Dias, Amit; Gouider, Riadh; Shahar, Suzana; Ashby-Mitchell, Kimberly; Prince, Martin; Dua, Tarun. 2022. Frontiers in neurology. 12: . 765584
Change in CAIDE Dementia Risk Score and neuroimaging biomarkers during a 2-year multidomain lifestyle randomized controlled trial: results of a post-hoc subgroup analysis
Stephen, Ruth; Ngandu, Tiia; Liu, Yawu; Peltonen, Markku; Antikainen, Riitta; Kemppainen, Nina; Laatikainen, Tiina; Lötjönen, Jyrki; Rinne, Juha; Strandberg, Timo; Tuomilehto, Jaakko; Vanninen, Ritva; Soininen, Hilkka; Kivipelto, Miia; Solomon, Alina. 2021. Journals of gerontology series a: biological sciences and medical sciences. 76: 1407-1414
Development of the First WHO Guidelines for Risk Reduction of Cognitive Decline and Dementia: Lessons Learned and Future Directions
Stephen, Ruth; Barbera, Mariagnese; Peters, Ruth; Ee, Nicole; Zheng, Lidan; Lehtisalo, Jenni; Kulmala, Jenni; Håkansson, Krister; Chowdhary, Neerja; Dua, Tarun; Solomon, Alina; Anstey, Kaarin J; Kivipelto, Miia. 2021. Frontiers in neurology. 12: 763573
Multidomain interventions: state-of-the-art and future directions for protocols to implement precision dementia risk reduction. A user manual for Brain Health Services-part 4 of 6
Solomon, Alina; Stephen, Ruth; Altomare, Daniele; Carrera, Emmanuel; Frisoni, Giovanni B.; Kulmala, Jenni; Molinuevo, José Luis; Nilsson, Peter; Ngandu, Tiia; Ribaldi, Federica; Vellas, Bruno; Scheltens, Philip; Kivipelto, Miia; European Task Force for Brain Health Services. 2021. Alzheimer's research and therapy. 13: 171
Sex and gender differences in genetic and lifestyle risk and protective factors for dementia
Sindi, Shireen; Toopchiani, Sima; Barbera, Mariagnese; Håkansson, Krister; Lehtisalo, Jenni; Rosenberg, Anna; Stephen, Ruth; Udeh-Momoh, Chinedu; Kivipelto, Miia. Teoksessa: Ferretti, Maria Teresa; Schumacher Dimech, Annemarie; Santuccione Chadha, Antonella(toim.) , 2021. Sex and Gender Differences in Alzheimer's Disease. s. 269-308. Academic press
Biomarker validation of a dementia risk prediction score
Stephen, Ruth; Soininen, Hilkka. 2020. Nature reviews neurology. 16: 135-136
The Finnish geriatric intervention study to prevent cognitive impairment and disability (FINGER): Findings from the structural brain MRI sub-study
Stephen, Ruth. 2020. Publications of the University of Eastern Finland. Dissertations in Health Sciences
White Matter Changes on Diffusion Tensor Imaging in the FINGER Randomized Controlled Trial
Stephen, Ruth; Solomon, Alina; Ngandu, Tiia; Levälahti, Esko; Rinne, Juha O; Kemppainen, Nina; Parkkola, Riitta; Antikainen, Riitta; Strandberg, Timo; Kivipelto, Miia; Soininen, Hilkka; Liu, Yawu. 2020. Journal of Alzheimer's disease. 78: 75-86
Brain volumes and cortical thickness on MRI in the Finnish Geriatric Intervention Study to Prevent Cognitive Impairment and Disability (FINGER)
Stephen, R; Liu, Y; Ngandu, T; Antikainen, R; Hulkkonen, J; Koikkalainen, J; Kemppainen, N; Lötjönen, J; Levälahti, E; Parkkola, R; Pippola, P; Rinne, J; Strandberg, T; Tuomilehto, J; Vanninen, R; Kivipelto, M; Soininen, H; Solomon, A. 2019. Alzheimer's research and therapy. 11: 53
Associations of CAIDE Dementia Risk Score with MRI, PIB-PET measures, and cognition
Stephen R, Liu Y, Ngandu T, Rinne JO, Kemppainen N, Parkkola R, Laatikainen T, Paajanen T, Hänninen T, Strandberg T, Antikainen R, Tuomilehto J, Keinänen Kiukaanniemi S, Vanninen R, Helisalmi S, Levälahti E, Kivipelto M, Soininen H, Solomon A. 2017. Journal of Alzheimer's disease. 59: 695-705
Brain amyloid load and its associations with cognition and vascular risk factors in FINGER study
Kemppainen Nina, Johansson Jarkko, Teuho Jarmo, Parkkola Riitta, Joutsa Juho, Ngandu Tiika, Solomon Alina, Stephen Ruth, Liu Yawu, Hänninen Tuomo, Paajanen Teemu, Laatikainen Tiina, Soininen Hilkka, Jula Antti, Rokka Johanna, Rissanen Eero, Vahlberg Tero, Peltoniemi Julia, Kivipelto Miia, Rinne Juha O. 2017. Neurology. 2018; 90: e206-e213
Physical Activity and Alzheimer's Disease: A Systematic Review
Stephen Ruth, Hongisto Kristiina, Solomon Alina, Lönnroos Eija. 2017. Journals of gerontology series a: biological sciences and medical sciences. 72: 733-739

Refine your search

Research groups

Keywords

The Australian National University Alzheimer's Disease Risk Index (ANU‐ADRI) score as a predictor for cognitive decline and potential surrogate outcome in the FINGER lifestyle randomized controlled trial

Association of tooth count with cognitive decline and dementia in the Finnish adult population

Dementia prevention in memory clinics: recommendations from the European task force for brain health services

The role of brain integrity in the association between occupational complexity and cognitive performance in subjects with increased risk of dementia

Dementia Risk Scores and Their Role in the Implementation of Risk Reduction Guidelines

Periodontal health, cognitive decline, and dementia: A systematic review and meta‐analysis of longitudinal studies

Reducing the Risk of Cognitive Decline and Dementia: WHO Recommendations

Change in CAIDE Dementia Risk Score and neuroimaging biomarkers during a 2-year multidomain lifestyle randomized controlled trial: results of a post-hoc subgroup analysis

Development of the First WHO Guidelines for Risk Reduction of Cognitive Decline and Dementia: Lessons Learned and Future Directions

Multidomain interventions: state-of-the-art and future directions for protocols to implement precision dementia risk reduction. A user manual for Brain Health Services-part 4 of 6

Sex and gender differences in genetic and lifestyle risk and protective factors for dementia

Biomarker validation of a dementia risk prediction score

The Finnish geriatric intervention study to prevent cognitive impairment and disability (FINGER): Findings from the structural brain MRI sub-study

White Matter Changes on Diffusion Tensor Imaging in the FINGER Randomized Controlled Trial

Brain volumes and cortical thickness on MRI in the Finnish Geriatric Intervention Study to Prevent Cognitive Impairment and Disability (FINGER)

Associations of CAIDE Dementia Risk Score with MRI, PIB-PET measures, and cognition

Brain amyloid load and its associations with cognition and vascular risk factors in FINGER study

Physical Activity and Alzheimer's Disease: A Systematic Review