RUTH STEPHEN
Postdoctoral Researcher
My research interests are the prevention of Alzheimer's disease and dementia with a special focus on dementia risk scores, biomarkers and interventions.
Contact info
Organization
School of Medicine, Institute of Clinical Medicine
ruth.stephen@uef.fi
Phone
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Keywords
CAIDE
clinical research
clinical trials
dementia
MRI
multimodal interventions
neurology
prevention
public health
risk factors
Research groups and research projects
Nordic Brain Network, led by Prof. Miia Kivipelto
Research groups - UEF
Publications
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Sex and gender differences in genetic and lifestyle risk and protective factors for dementia. Sindi, Shireen; Toopchiani, Sima; Barbera, Mariagnese; Håkansson, Krister; Lehtisalo, Jenni; Rosenberg, Anna; Stephen, Ruth; Udeh-Momoh, Chinedu; Kivipelto, Miia / Sex and Gender Differences in Alzheimer's Disease. 2021. 2021
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Solomon, Alina; Stephen, Ruth; Altomare, Daniele; Carrera, Emmanuel; Frisoni, Giovanni B.; Kulmala, Jenni; Molinuevo, José Luis; Nilsson, Peter; Ngandu, Tiia; Ribaldi, Federica; Vellas, Bruno; Scheltens, Philip; Kivipelto, Miia; European Task Force for Brain Health Services. 2021. Multidomain interventions: state-of-the-art and future directions for protocols to implement precision dementia risk reduction. A user manual for Brain Health Services-part 4 of 6 Alzheimer's research and therapy 13 1: 171. 2021
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Stephen, Ruth; Barbera, Mariagnese; Peters, Ruth; Ee, Nicole; Zheng, Lidan; Lehtisalo, Jenni; Kulmala, Jenni; Håkansson, Krister; Chowdhary, Neerja; Dua, Tarun; Solomon, Alina; Anstey, Kaarin J; Kivipelto, Miia. 2021. Development of the First WHO Guidelines for Risk Reduction of Cognitive Decline and Dementia: Lessons Learned and Future Directions Frontiers in neurology 12: 763573. 2021
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Stephen, Ruth; Ngandu, Tiia; Liu, Yawu; Peltonen, Markku; Antikainen, Riitta; Kemppainen, Nina; Laatikainen, Tiina; Lötjönen, Jyrki; Rinne, Juha; Strandberg, Timo; Tuomilehto, Jaakko; Vanninen, Ritva; Soininen, Hilkka; Kivipelto, Miia; Solomon, Alina. 2021. Change in CAIDE Dementia Risk Score and neuroimaging biomarkers during a 2-year multidomain lifestyle randomized controlled trial: results of a post-hoc subgroup analysis Journals of gerontology series a: biological sciences and medical sciences 76 8: 1407-1414. 2021
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Stephen, Ruth (ed.) . 2020. The Finnish geriatric intervention study to prevent cognitive impairment and disability (FINGER): Findings from the structural brain MRI sub-study. Itä-Suomen yliopisto. Publications of the University of Eastern Finland. Dissertations in Health Sciences 572. 2020
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Stephen, Ruth; Soininen, Hilkka. 2020. Biomarker validation of a dementia risk prediction score Nature reviews neurology 16: 135-136. 2020
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Stephen, Ruth; Solomon, Alina; Ngandu, Tiia; Levälahti, Esko; Rinne, Juha O; Kemppainen, Nina; Parkkola, Riitta; Antikainen, Riitta; Strandberg, Timo; Kivipelto, Miia; Soininen, Hilkka; Liu, Yawu. 2020. White Matter Changes on Diffusion Tensor Imaging in the FINGER Randomized Controlled Trial Journal of Alzheimer's disease 78 1: 75-86. 2020
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Stephen, R; Liu, Y; Ngandu, T; Antikainen, R; Hulkkonen, J; Koikkalainen, J; Kemppainen, N; Lötjönen, J; Levälahti, E; Parkkola, R; Pippola, P; Rinne, J; Strandberg, T; Tuomilehto, J; Vanninen, R; Kivipelto, M; Soininen, H; Solomon, A. 2019. Brain volumes and cortical thickness on MRI in the Finnish Geriatric Intervention Study to Prevent Cognitive Impairment and Disability (FINGER) Alzheimer's research and therapy 11: 53. 2019
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Kemppainen Nina, Johansson Jarkko, Teuho Jarmo, Parkkola Riitta, Joutsa Juho, Ngandu Tiika, Solomon Alina, Stephen Ruth, Liu Yawu, Hänninen Tuomo, Paajanen Teemu, Laatikainen Tiina, Soininen Hilkka, Jula Antti, Rokka Johanna, Rissanen Eero, Vahlberg Tero, Peltoniemi Julia, Kivipelto Miia, Rinne Juha O. 2017. Brain amyloid load and its associations with cognition and vascular risk factors in FINGER study Neurology 2018; 90 3: e206-e213. 2017
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Stephen R, Liu Y, Ngandu T, Rinne JO, Kemppainen N, Parkkola R, Laatikainen T, Paajanen T, Hänninen T, Strandberg T, Antikainen R, Tuomilehto J, Keinänen Kiukaanniemi S, Vanninen R, Helisalmi S, Levälahti E, Kivipelto M, Soininen H, Solomon A. 2017. Associations of CAIDE Dementia Risk Score with MRI, PIB-PET measures, and cognition. Journal of Alzheimer's Disease 59 2: 695-705. 2017