Tapio Nevalainen
University Lecturer
School of Pharmacy, Faculty of Health Sciences
[email protected] | +358 40 355 2479
Research groups
Publications
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Synthesis, relative configuration and CB1 receptor affinity studies for a set of 1,2,3-triazole derivatives
Szafrański, Przemysław W; Siwek, Agata; Smaga-Maślanka, Irena; Pomierny-Chamioło, Lucyna; Ilnicki, Piotr; Żuchowski, Grzegorz; Nevalainen, Tapio; Filip, Małgorzata; Zajdel, Paweł; Cegła, Marek T. 2023. Journal of molecular structure. 1282: A1 Journal article (refereed), original research -
Evaluation of FASN inhibitors by a versatile toolkit reveals differences in pharmacology between human and rodent FASN preparations and in antiproliferative efficacy in vitro vs. in situ in human cancer cells
Singha, Prosanta; Mäklin, Kiira; Vihavainen, Taina; Laitinen, Tuomo; Nevalainen, Tapio; Patil, Mahadeo; Tonduru, Arun; Poso, Antti; Laitinen, Jarmo; Savinainen, Juha. 2020. European journal of pharmaceutical sciences. 149: 105321 A1 Journal article (refereed), original research -
CB2 receptor activation causes an ERK1/2-dependent inflammatory response in human RPE cells
Hytti M, Andjelic S, Josifovska N, Piippo N, Korhonen E, Hawlina M, Kaarniranta K, Nevalainen TJ, Petrovski G, Parkkari T, Kauppinen A. 2017. Scientific reports. 7: 16169 A1 Journal article (refereed), original research -
Design, Synthesis, and Biological Evaluation of 2,4-Dihydropyrano[2,3-c]pyrazole Derivatives as Autotaxin Inhibitors
Pantsar T, Singha P, Nevalainen TJ, Koshevoy I, Leppänen J, Poso A, Niskanen JMA, Pasonen-Seppänen S, Savinainen JR, Laitinen T, Laitinen JT. 2017. European journal of pharmaceutical sciences. 107: 97-111 A1 Journal article (refereed), original research -
Chemoproteomic, biochemical and pharmacological approaches in the discovery of inhibitors targeting human alfa/beta-hydrolase domain containing 11 (ABHD11)
Navia-Paldanius D, Patel JZ, López Navarro M, Jakupovic H, Goffart S, Pasonen-Seppänen S, Nevalainen TJ, Jääskeläinen T, Laitinen T, Laitinen JT, Savinainen JR. 2016. European journal of pharmaceutical sciences. 93: 253-263 A1 Journal article (refereed), original research -
In vivo characterization of the ultrapotent monoacylglycerol lipase inhibitor {4-[bis-(benzo[d][1,3]dioxol-5-yl)methyl]-piperidin-1-yl} (1H-1,2,4-triazol-1-yl)methanone (JJKK-048)
Aaltonen Niina, Kedzierska Ewa, Orzelska-Gorka Jolanta, Lehtonen Marko, Navia-Paldanius Dina, Jakupovic Hermina, Savinainen Juha, Nevalainen Tapio, Laitinen Jarmo T, Parkkari Teija, Gynther Mikko. 2016. Journal of pharmacology and experimental therapeutics. 359: 62-72 A1 Journal article (refereed), original research -
Comparative molecular field analysis and molecular dynamics studies of alpha/beta hydrolase domain containing 6 (ABHD6) inhibitors
Kaczor Agnieszka A, Targowska-Duda Katarzyna M, Patel Jayendra Z, Laitinen Tuomo, Parkkari Teija, Adams Yahaya, Nevalainen Tapio J, Poso Antti. 2015. Journal of molecular modeling. 21:250: . A1 Journal article (refereed), original research -
Inhibitory effects and oxidation of 6-methylcoumarin, 7-methylcoumarin and 7-formylcoumarin via human CYP2A6 and its mouse and pig orthologous enzymes
Juvonen Risto O, Kuusisto Mira, Fohrgrup Carolin, Pitkänen Mari H, Nevalainen Tapio J, Auriola Seppo, Raunio Hannu, Pasanen Markku, Pentikäinen Olli T. 2015. Xenobiotica. 2016; 46: 14-24 A1 Journal article (refereed), original research -
Loratadine analogues as MAGL inhibitors
Patel Jayendra Z, Ahenkorah Stephen, Vaara Miia, Staszewski Marek, Adams Yahaya, Laitinen Tuomo, Navia-Paldanius Dina, Parkkari Teija, Savinainen Juha R, Walczynski Krzysztof, Laitinen Jarmo T, Nevalainen Tapio J. 2015. Bioorganic and medicinal chemistry letters. 25: 1436-1442 A1 Journal article (refereed), original research -
Potent and selective N-(4-sulfamoylphenyl)thiourea-based GPR55 agonists
Yrjölä Sari, Parkkari Teija, Navia-Paldanius Dina, Laitinen Tuomo, Kaczor Agnieszka A, Kokkola Tarja, Adusei-Mensah Frank, Savinainen Juha R, Laitinen Jarmo T, Poso Antti, Alexander Amy, Penman June, Stott Lisa, Anskat Marie, Irving Andrew J, Nevalainen Tapio J. 2015. European journal of medicinal chemistry. 107 (2016): 119-132 A1 Journal article (refereed), original research