Tarja Kokkola
Research Coordinator
Quality Coordinator
PhD, docent
Institute of Clinical Medicine, School of Medicine, Faculty of Health Sciences
tarja.kokkola@uef.fi | +358 46 922 7547
- Management and development of quality systems at the Clinical Research Centre / School of Medicine, including two diagnostic laboratories with ISO 15189 accreditation.
- Development, validation and quality assurance of methodology and instrumentation (clinical chemistry, clinical research, biochemistry).
- Lectures and training in quality management, auditing and risk assessment.
- Several collaborative research projects (Biomarkers of neurodegenerative diseases, type 2 diabetes, sirtuins).
Research groups
Publications
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A FinnGen pilot clinical recall study for Alzheimer’s disease
Julkunen, Valtteri; Schwarz, Claudia; Kalapudas, Juho; Hallikainen, Merja; Piironen, Aino-Kaisa; Mannermaa, Arto; Kujala, Hanna; Laitinen, Timo; Kosma, Veli-Matti; Paajanen, Teemu I.; Kälviäinen, Reetta; Hiltunen, Mikko; Herukka, Sanna-Kaisa; Kärkkäinen, Sari; Kokkola, Tarja; Urjansson, Mia; FinnGen; Perola, Markus; Palotie, Aarno; Vuoksimaa, Eero; Runz, Heiko. 2023. Scientific reports. 13: . 12641 -
Cerebrospinal Fluid Diagnostics of Alzheimer's Disease in Patients with Idiopathic Normal Pressure Hydrocephalus
Vanninen, Aleksi; Lukkarinen, Heikki; Kokkola, Tarja; Koivisto, Anne M.; Kokki, Merja; Musialowicz, Tadeusz; Hiltunen, Mikko; Zetterberg, Henrik; Leinonen, Ville; Herukka, Sanna Kaisa; Rauramaa, Tuomas. 2023. Journal of Alzheimer's disease. 94: 727-736 -
Concordance of Alzheimer’s Disease-Related Biomarkers Between Intraventricular and Lumbar Cerebrospinal Fluid in Idiopathic Normal Pressure Hydrocephalus
Lukkarinen, Heikki; Vanninen, Aleksi; Tesseur, Ina; Pemberton, Darrel; Van Der Ark, Peter; Kokkola, Tarja; Herukka, Sanna-Kaisa; Rauramaa, Tuomas; Hiltunen, Mikko; Blennow, Kaj; Zetterberg, Henrik; Leinonen, Ville. 2023. Journal of Alzheimer's disease. 91: 305-319 -
Discovery of drug–omics associations in type 2 diabetes with generative deep-learning models
Allesøe, Rosa Lundbye; Lundgaard, Agnete Troen; Hernández Medina, Ricardo; Aguayo-Orozco, Alejandro; Johansen, Joachim; Nissen, Jakob Nybo; Brorsson, Caroline; Mazzoni, Gianluca; Niu, Lili; Biel, Jorge Hernansanz; Brasas, Valentas; Webel, Henry; Benros, Michael Eriksen; Pedersen, Anders Gorm; Chmura, Piotr Jaroslaw; Jacobsen, Ulrik Plesner; Mari, Andrea; Koivula, Robert; Mahajan, Anubha; Vinuela, Ana; Tajes, Juan Fernandez; Sharma, Sapna; Haid, Mark; Hong, Mun-Gwan; Musholt, Petra B.; De Masi, F. 2023. Nature biotechnology. 41: 399-408 -
Genetic analysis of blood molecular phenotypes reveals common properties in the regulatory networks affecting complex traits
Brown, Andrew A.; Fernandez-Tajes, Juan J.; Hong, Mun-gwan; Brorsson, Caroline A.; Koivula, Robert W.; Davtian, David; Dupuis, Théo; Sartori, Ambra; Michalettou, Theodora-Dafni; Forgie, Ian M.; Adam, Jonathan; Allin, Kristine H.; Caiazzo, Robert; Cederberg, Henna; De Masi, Federico; Elders, Petra J. M.; Giordano, Giuseppe N.; Haid, Mark; Hansen, Torben; Hansen, Tue H.; Hattersley, Andrew T.; Heggie, Alison J.; Howald, Cédric; Jones, Angus G.; Kokkola, Tarja; Laakso, Markku; Mahajan, Anubha; Mar. 2023. Nature communications. 14: . 5062 -
Novel cerebrospinal fluid biomarkers correlating with shunt responsiveness in patients with idiopathic normal pressure hydrocephalus
Weiner, Sophia; Junkkari, Antti; Sauer, Mathias; Luikku, Antti; Rauramaa, Tuomas; Kokkola, Tarja; Herukka, Sanna-Kaisa; Blennow, Kaj; Zetterberg, Henrik; Leinonen, Ville; Gobom, Johan. 2023. Fluids and barriers of the cns. 20: . 40 -
Protective Alzheimer's disease-associated APP A673T variant predominantly decreases sAPPβ levels in cerebrospinal fluid and 2D/3D cell culture models
Wittrahm, Rebekka; Takalo, Mari; Kuulasmaa, Teemu; Mäkinen, Petra M; Mäkinen, Petri; Končarević, Saša; Fartzdinov, Vadim; Selzer, Stefan; Kokkola, Tarja; Antikainen, Leila; Martiskainen, Henna; Kemppainen, Susanna; Marttinen, Mikael; Jeskanen, Heli; Rostalski, Hannah; Rahunen, Eija; Kivipelto, Miia; Ngandu, Tiia; Natunen, Teemu; Lambert, Jean-Charles; Tanzi, Rudolph E; Kim, Doo Yeon; Rauramaa, Tuomas; Herukka, Sanna-Kaisa; Soininen, Hilkka; Laakso, Markku; Pike, Ian; Leinonen, Ville; Haapasalo, . 2023. Neurobiology of disease. 182: -
Serum Cathepsin S Levels Do Not Show Alterations in Different Clinical, Neuropathological, or Genetic Subtypes of Frontotemporal Dementia Patients nor in Comparison to Healthy Control Individuals
Heikkinen, Sami; Huber, Nadine; Katisko, Kasper; Kokkola, Tarja; Hartikainen, Päivi; Krüger, Johanna; Leinonen, Ville; Korhonen, Ville E; Herukka, Sanna-Kaisa; Remes, Anne M; Borroni, Barbara; Alberici, Antonella; Libri, Ilenia; Solje, Eino; Haapasalo, Annakaisa. 2023. Journal of Alzheimer's disease. 93: 395-401 -
Four groups of type 2 diabetes contribute to the etiological and clinical heterogeneity in newly diagnosed individuals: An IMI DIRECT study
Wesolowska-Andersen, Agata; Brorsson, Caroline A.; Bizzotto, Roberto; Mari, Andrea; Tura, Andrea; Koivula, Robert; Mahajan, Anubha; Vinuela, Ana; Tajes, Juan Fernandez; Sharma, Sapna; Haid, Mark; Prehn, Cornelia; Artati, Anna; Hong, Mun-Gwan; Musholt, Petra B.; Kurbasic, Azra; De Masi, Federico; Tsirigos, Kostas; Pedersen, Helle Krogh; Gudmundsdottir, Valborg; Thomas, Cecilia Engel; Banasik, Karina; Jennison, Chrisopher; Jones, Angus; Kennedy, Gwen; Bell, Jimmy; Thomas, Louise; Frost, Gary; Thom. 2022. Cell reports medicine. 3: -
Laadukasta palvelua ja tutkimusta Itä-Suomen yliopiston aivotutkimusyksikön Biomarkkerilaboratoriossa
Kokkola, Tarja; Kärkkäinen, Sari; Herukka, Sanna-Kaisa. 2022. Kliin lab. 39: 72-75