Tomi Tuomainen - UEFConnect

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Research groups

Molecular Physiology 01.01.2009 -

Publications

18/18 items

Blueprint of the distinct metabolite profiles of healthy pig heart chambers
Haikonen, Retu; Meuronen, Topi; Koistinen, Ville; Kärkkäinen, Olli; Tuomainen, Tomi; Solano-Aguilar, Gloria I; Urban, Joseph F; Lehtonen, Marko; Tavi, Pasi; Hanhineva, Kati. 2025. Journal of molecular and cellular cardiology plus. 13: . 100462 A1 Journal article (refereed), original research
Presenilin-1 ΔE9 mutation associated sarcoplasmic reticulum leak alters [Ca2+]i distribution in human iPSC-derived cardiomyocytes
Naumenko, Nikolay; Koivumäki, Jussi T; Lunko, Olesia; Tuomainen, Tomi; Leigh, Robert; Rabiee, Mina; Laurila, Jalmari; Oksanen, Minna; Lehtonen, Sarka; Koistinaho, Jari; Tavi, Pasi. 2024. Journal of molecular and cellular cardiology. 193: 78-87 A1 Journal article (refereed), original research
BIN1, Myotubularin, and Dynamin-2 Coordinate T-Tubule Growth in Cardiomyocytes
Perdreau-Dahl, Harmonie; Lipsett, David B; Frisk, Michael; Kermani, Fatemeh; Carlson, Cathrine R; Brech, Andreas; Shen, Xin; Bergan-Dahl, Anna; Hou, Yufeng; Tuomainen, Tomi; Tavi, Pasi; Jones, Peter P; Lunde, Marianne; Wasserstrom, J Andrew.; Laporte, Jocelyn; Ullrich, Nina D; Christensen, Geir; Morth, J Preben; Louch, William E. 2023. Circulation research. 132: e188-e205 A1 Journal article (refereed), original research
PGC-1α deficiency reveals sex-specific links between cardiac energy metabolism and EC-coupling during development of heart failure in mice
Naumenko, Nikolay; Mutikainen, Maija; Holappa, Lari; Ruas, Jorge L; Tuomainen, Tomi; Tavi, Pasi. 2022. Cardiovascular research. 118: 1520-1534 A1 Journal article (refereed), original research
PGC-1α4 Interacts with REST to Upregulate Neuronal Genes and Augment Energy Consumption in Developing Cardiomyocytes
Tuomainen, Tomi; Naumenko, Nikolay; Mutikainen, Maija; Shakirzyanova, Anastasia; Sczelecki, Sarah; Estall, Jennifer L.; Ruas, Jorge L.; Tavi, Pasi. 2022. Cells. 11: A1 Journal article (refereed), original research
The Ablation of VEGFR-1 Signaling Promotes Pressure Overload-Induced Cardiac Dysfunction and Sudden Death
Tirronen, Annakaisa; Downes, Nicholas L; Huusko, Jenni; Laakkonen, Johanna P; Tuomainen, Tomi; Tavi, Pasi; Hedman, Marja; Ylä-Herttuala, Seppo. 2021. Biomolecules. 11: 452 A1 Journal article (refereed), original research
Short High-Fat Diet Interferes With the Physiological Maturation of the Late Adolescent Mouse Heart
Hynynen, H; Mutikainen, M; Naumenko, N; Shakirzyanova, A; Tuomainen, T; Tavi, P. 2020. Physiological reports. 8: e14474 A1 Journal article (refereed), original research
Nrf2 and SQSTM1/p62 jointly contribute to mesenchymal transition and invasion in glioblastoma
Pölönen, P; Jawahar Deen, A; Leinonen, HM; Jyrkkänen, HK; Kuosmanen, S; Mononen, M; Jain, A; Tuomainen, T; Pasonen-Seppänen, S; Hartikainen, JM; Mannermaa, A; Nykter, M; Tavi, P; Johansen, T; Heinäniemi, M; Levonen, AL. 2019. Oncogene. 38: 7473-7490 A1 Journal article (refereed), original research
Structural Immaturity of Human iPSC-Derived Cardiomyocytes: In Silico Investigation of Effects on Function and Disease Modeling
Koivumäki, Jussi T; Naumenko, Nikolay; Tuomainen, Tomi; Takalo, Jouni; Oksanen, Minna; Puttonen, Katja A; Lehtonen, Sarka; Kuusisto, Johanna; Laakso, Markku; Koistinaho, Jari; Tavi, Pasi. 2018. Frontiers in physiology. 9: 80 A1 Journal article (refereed), original research
Whole grain intake associated molecule 5-aminovaleric acid betaine decreases ß-oxidation of fatty acids in mouse cardiomyocytes
Kärkkäinen, Olli; Tuomainen, Tomi; Koistinen, Ville; Tuomainen, Marjo; Leppänen, Jukka; Laitinen, Tuomo; Lehtonen, Marko; Rysä, Jaana; Auriola, Seppo; Poso, Antti; Tavi, Pasi; Hanhineva, Kati. 2018. Scientific reports. 8: 13036 A1 Journal article (refereed), original research
Genome-Wide Dynamics of Nascent Noncoding RNA Transcription in Porcine Heart After Myocardial Infarction
Kaikkonen Minna U, Halonen Paavo, Liu Oscar Hsin-Fu, Turunen Tiia A, Pajula Juho, Moreau Pierre, Selvarajan Ilakya, Tuomainen Tomi, Aavik Einari, Tavi Pasi, Ylä-Herttuala Seppo. 2017. Circulation: cardiovascular genetics. 10: e001702 A1 Journal article (refereed), original research
The role of cardiac energy metabolism in cardiac hypertrophy and failure
Tuomainen Tomi, Tavi Pasi. 2017. Experimental cell research. 360: 12-18 A1 Journal article (refereed), original research
Vascular Endothelial Growth Factor-B Induces a Distinct Electrophysiological Phenotype in Mouse Heart
Naumenko N, Huusko J, Tuomainen T, Koivumäki JT, Merentie M, Gurzeler E, Alitalo K, Kivelä R, Ylä-Herttuala S, Tavi P. 2017. Frontiers in physiology. 8: 373 A1 Journal article (refereed), original research
Peroxisome Proliferator-activated Receptor-gamma Coactivator 1 alfa1 Induces a Cardiac Excitation-contraction Coupling Phenotype Without Metabolic Remodelling
Mutikainen Maija, Tuomainen Tomi, Naumenko Nikolay, Huusko Jenni, Smirin Boris, Laidinen S, Kokki K, Hynynen H, Ylä-Herttuala S, Heinäniemi M, Ruas JL, Tavi P. 2016. Journal of physiology: london. 594: 7049-7071 A1 Journal article (refereed), original research
Potassium channel interacting protein 2 (KChIP2) is not a transcriptional regulator of cardiac electrical remodeling
Winther SV, Tuomainen T, Borup R, Tavi P, Antoons G, Thomsen MB. 2016. Scientific reports. 6: 28760 A1 Journal article (refereed), original research
Ca2+-activated K+ current is essential for maintaining excitability and gene transcription in early embryonic cardiomyocytes
Karppinen S, Rapila R, Naumenko N, Tuomainen T, Koivumäki JT, Hänninen SL, Korhonen T, Tavi P. 2015. Acta physiologica. [epub 28 JUN 2015]: - A1 Journal article (refereed), original research
Endothelial Bmx tyrosine kinase activity is essential for myocardial hypertrophy and remodeling
Holopainen T, Räsänen M, Anisimov A, Tuomainen T, Zheng W, Tvorogov D, Hulmi JJ, Andersson LC, Cenni B, Tavi P, Mervaala E, Kivelä R, Alitalo K. 2015. Proceedings of the National Academy of Sciences of the United States of America. 112: 13036-13068 A1 Journal article (refereed), original research
Hypoxia-inducible factor 1-induced G protein-coupled receptor 35 expression is an early marker of progressive cardiac remodelling
Ronkainen Veli-Pekka, Tuomainen Tomi, Huusko Jenni, Laidinen Svetlana, Malinen Marjo, Palvimo Jorma J, Ylä-Herttuala Seppo, Vuolteenaho Olli, Tavi Pasi. 2014. Cardiovascular research. 2014 Jan 1;101(1): 69-77 A1 Journal article (refereed), original research