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Alina Solomon

Alina Solomon

Apulaisprofessori

Lääketieteen laitos, Kliinisen lääketieteen yksikkö

alina.solomon@uef.fi | 040 355 2015

0403552015
040 3552015
040 355 2015
+358 40 355 2015
+35840 355 2015
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Tiedot Julkaisut

Tutkimusryhmät

Aivotutkimusyksikkö 01.01.2022 -
Clinical Alzheimer Research 01.01.2022 -
UEF - Nordic-UK Brain Network (UEF-NBN) 01.01.2022 -

Projektit

CAIDE - Cardiovascular Risk Factors, Aging and Dementia Päättynyt 01.01.1998 - 31.12.2022
e-FINGERS virtuaalinen fasilitaattori yksilöllisen aivoterveyden edistämiseksi ja dementian ehkäisyksi 01.06.2022 - 31.03.2023
Neuro-Innovation 01.05.2021 - 30.04.2026

Julkaisut

97 kappaletta

Quantifying dementia prevention potential in the FINGER randomized controlled trial using the LIBRA prevention index.
Deckers, Kay; Köhler, Sebastian; Ngandu, Tiia; Antikainen, Riitta; Laatikainen, Tiina; Soininen, Hilkka; Strandberg, Timo; Verhey, Frans; Kivipelto, Miia; Solomon, Alina. Alzheimer's & dementia 17 7: 1205-1212. 2021
Facilitators and barriers to implementing lifestyle intervention programme to prevent cognitive decline
Kulmala, J; Rosenberg, A; Ngandu, T; Hemiö, K; Tenkula, T; Hyytiä, A; Vienola, M; Huhtamäki-Kuoppala, M; Saarinen, A; Korkki, S; Laatikainen, T; Solomon, A; Kivipelto, M. European journal of public health 31 4: 816-822. 2021
Personal Social Networks of Community-Dwelling Oldest Old During the Covid-19 Pandemic - A Qualitative Study
Kulmala, Jenni; Tiilikainen, Elisa; Lisko, Inna; Ngandu, Tiia; Kivipelto, Miia; Solomon, Alina. Frontiers in public health 9: 770965. 2021
Changes in Lifestyle, Behaviors, and Risk Factors for Cognitive Impairment in Older Persons During the First Wave of the Coronavirus Disease 2019 Pandemic in Finland: Results From the FINGER Study
Lehtisalo, Jenni; Palmer, Katie; Mangialasche, Francesca; Solomon, Alina; Kivipelto, Miia; Ngandu, Tiia. Frontiers in psychiatry 12: 624125. 2021
The effect of adherence on cognition in a multidomain lifestyle intervention (FINGER)
Ngandu, Tiia; Lehtisalo, Jenni; Korkki, Saana; Solomon, Alina; Coley, Nicola; Antikainen, Riitta; Bäckman, Lars; Hänninen, Tuomo; Lindström, Jaana; Laatikainen, Tiina; Paajanen, Teemu; Havulinna, Satu; Peltonen, Markku; Neely, Anna Stigsdotter; Strandberg, Timo; Tuomilehto, Jaakko; Soininen, Hilkka; Kivipelto, Miia. Alzheimer's & dementia First published: 20 October 2021: 1 - 10. 2021
Research diagnostic criteria for Alzheimer's disease: findings from the LipiDiDiet randomized controlled trial
Rosenberg, Anna; Solomon, Alina; Soininen, Hilkka; Visser, Pieter Jelle; Blennow, Kaj; Hartmann, Tobias; Kivipelto, Miia; on behalf of the LipiDiDiet clinical study group [incl. Hallikainen, Ilona; Hallikainen, Merja; Helisalmi, Seppo; Lappalainen, Tarja; Liu, Yawu; Paajanen, Teemu]. Alzheimer's research and therapy 13: 64. 2021
27-Hydroxycholesterol, cognition, and brain imaging markers in the FINGER randomized controlled trial
Sandebring-Matton, Anna; Goikolea, Julen; Björkhem, Ingemar; Paternain, Laura; Kemppainen, Nina; Laatikainen, Tiina; Ngandu, Tiia; Rinne, Juha; Soininen, Hilkka; Cedazo-Minguez, Angel; Solomon, Alina; Kivipelto, Miia. Alzheimer's research and therapy 13 1: 56. 2021
Telomere length change in a multidomain lifestyle intervention to prevent cognitive decline: a randomized clinical trial
Sindi, Shireen; Solomon, Alina; Kåreholt, Ingemar; Hovatta, Iiris; Antikainen, Riitta; Hänninen, Tuomo; Levälahti, Esko; Laatikainen, Tiina; Lehtisalo, Jenni; Lindström, Jaana; Paajanen, Teemu; Peltonen, Markku; Singh Khalsa, Dharma; Wolozin, Benjamin; Strandberg, Timo; Tuomilehto, Jaakko; Soininen, Hilkka; Ngandu, Tiia; Kivipelto, Miia; for the FINGER Study Group. Journals of gerontology series a: biological sciences and medical sciences 76 3: 491-498. 2021
Effect of a Multidomain Lifestyle Intervention on Estimated Dementia Risk
Solomon, Alina; Handels, Ron; Wimo, Anders; Antikainen, Riitta; Laatikainen, Tiina; Levälahti, Esko; Peltonen, Markku; Soininen, Hilkka; Strandberg, Timo; Tuomilehto, Jaakko; Kivipelto, Miia; Ngandu, Tiia. Journal of Alzheimer's disease 82 4: 1461-1466. 2021
Multidomain interventions: state-of-the-art and future directions for protocols to implement precision dementia risk reduction. A user manual for Brain Health Services-part 4 of 6
Solomon, Alina; Stephen, Ruth; Altomare, Daniele; Carrera, Emmanuel; Frisoni, Giovanni B.; Kulmala, Jenni; Molinuevo, José Luis; Nilsson, Peter; Ngandu, Tiia; Ribaldi, Federica; Vellas, Bruno; Scheltens, Philip; Kivipelto, Miia; European Task Force for Brain Health Services. Alzheimer's research and therapy 13 1: 171. 2021
Development of the First WHO Guidelines for Risk Reduction of Cognitive Decline and Dementia: Lessons Learned and Future Directions
Stephen, Ruth; Barbera, Mariagnese; Peters, Ruth; Ee, Nicole; Zheng, Lidan; Lehtisalo, Jenni; Kulmala, Jenni; Håkansson, Krister; Chowdhary, Neerja; Dua, Tarun; Solomon, Alina; Anstey, Kaarin J; Kivipelto, Miia. Frontiers in neurology 12: 763573. 2021
Change in CAIDE Dementia Risk Score and neuroimaging biomarkers during a 2-year multidomain lifestyle randomized controlled trial: results of a post-hoc subgroup analysis
Stephen, Ruth; Ngandu, Tiia; Liu, Yawu; Peltonen, Markku; Antikainen, Riitta; Kemppainen, Nina; Laatikainen, Tiina; Lötjönen, Jyrki; Rinne, Juha; Strandberg, Timo; Tuomilehto, Jaakko; Vanninen, Ritva; Soininen, Hilkka; Kivipelto, Miia; Solomon, Alina. Journals of gerontology series a: biological sciences and medical sciences 76 8: 1407-1414. 2021
Everyday Life Meaningfulness for the Community-Dwelling Oldest Old During the COVID-19 Pandemic
Tiilikainen, Elisa; Lisko, Inna; Kekkonen, Eija; Solomon, Alina; Ngandu, Tiia; Kivipelto, Miia; Kulmala, Jenni. Frontiers in psychology 12: 716428. 2021
Third follow-up of the Cardiovascular Risk Factors, Aging and Dementia (CAIDE) cohort investigating determinants of cognitive, physical, and psychosocial wellbeing among the oldest old: the CAIDE85+ study protocol
Barbera, Mariagnese; Kulmala, Jenni; Lisko, Inna; Pietilä, Eija; Rosenberg, Anna; Hallikainen, Ilona; Hallikainen, Merja; Laatikainen, Tiina; Lehtisalo, Jenni; Neuvonen, Elisa; Rusanen, Minna; Soininen, Hilkka; Tuomilehto, Jaakko; Ngandu, Tiia; Solomon, Alina; Kivipelto, Miia. Bmc geriatrics 20: 238. 2020
World-Wide FINGERS Network: A global approach to risk reduction and prevention of dementia
Kivipelto, M; Mangialasche, F; Snyder, HM; Allegri, R; Andrieu, S; Arai, H; Baker, L; Belleville, S; Brodaty, H; Brucki, SM; Calandri, I; Caramelli, P; Chen, C; Chertkow, H; Chew, E; Choi, SH; Chowdhary, N; Crivelli, L; De La Torre, R; Du, Y; et al. [Incl. Lehtisalo, J; Rosenberg, A; Soininen, H; Solomon, A]. Alzheimer's & dementia 16 7: 1078-1094. 2020
Late-life personality traits, cognitive impairment, and mortality in a population-based cohort
Neuvonen, Elisa; Hall, Anette; Tolppanen, Anna-Maija; Ngandu, Tiia; Rusanen, Minna; Laatikainen, Tiina; Soininen, Hilkka; Kivipelto, Miia; Solomon, Alina. International journal of geriatric psychiatry 35 9: 989-999. 2020
Association of Peripheral Insulin Resistance and Other Markers of Type 2 Diabetes Mellitus With Brain Amyloid Deposition in Healthy Individuals at Risk of Dementia
Pekkala, Timo; Hall, Anette; Mangialasche, Francesca; Kemppainen, Niina; Mecocci, Patrizia; Ngandu, Tiia; Rinne, Juha O; Soininen, Hilkka; Tuomilehto, Jaakko; Kivipelto. Miia; Solomon. Alina 1 2. Journal of Alzheimer's disease 76 4: 1243-1248. 2020
Detecting Amyloid Positivity in Elderly With Increased Risk of Cognitive Decline
Pekkala, Timo; Hall, Anette; Ngandu, Tiia; Gils, Mark van; Helisalmi, Seppo; Hänninen, Tuomo; Kemppainen, Nina; Liu, Yawu; Lötjönen, Jyrki; Paajanen, Teemu; Rinne, Juha O; Soininen, Hilkka; Kivipelto, Miia; Solomon, Alina. Frontiers in aging neuroscience 12: 228. 2020
White Matter Changes on Diffusion Tensor Imaging in the FINGER Randomized Controlled Trial
Stephen, Ruth; Solomon, Alina; Ngandu, Tiia; Levälahti, Esko; Rinne, Juha O; Kemppainen, Nina; Parkkola, Riitta; Antikainen, Riitta; Strandberg, Timo; Kivipelto, Miia; Soininen, Hilkka; Liu, Yawu. Journal of Alzheimer's disease 78 1: 75-86. 2020
Prescreening for European Prevention of Alzheimer Dementia (EPAD) trial-ready cohort: impact of AD risk factors and recruitment settings
Vermunt, L; Muniz-Terrera, G; Ter Meulen, L; Veal, C; Blennow, K; Campbell, A; Carrié, I; Delrieu, J; Fauria, K; Huesa Rodríguez, G; Ingala, S; Jenkins, N; Molinuevo, JL; Ousset, PJ; Porteous, D; Prins, ND; Solomon, A; Tom, BD; Zetterberg, H; Zwan, M; et al.. Alzheimers research and therapy 12: 8. 2020
Long-term dementia risk prediction by the LIBRA score: a 30-year follow-up of the CAIDE study
Deckers, K; Barbera, M; Köhler, S; Ngandu, T; van Boxtel, M; Rusanen, M; Laatikainen, T; Verhey, F; Soininen, H; Kivipelto, M; Solomon, A. International journal of geriatric psychiatry 2020; 35 2: 195-203. 2019
From prediction to dementia prevention
Solomon, A; Ngandu, T; Kivipelto, M / New Developments in Dementia Prevention Research : State of the Art and Future Possibilities. 2019. 2019
Prediction models for dementia and neuropathology in the oldest old: the Vantaa 85+ cohort study
Hall, A; Pekkala, T; Polvikoski, T; van Gils, M; Kivipelto, M; Lötjönen, J; Mattila, J; Kero, M; Myllykangas, L; Mäkelä, M; Oinas, M; Paetau, A; Soininen, H; Tanskanen, M; Solomon, A. Alzheimer's research and therapy 11: 11. 2019
Alzheimer's Disease Composite Score: A Post-Hoc Analysis Using Data from the LipiDiDiet Trial in Prodromal Alzheimer's Disease
Hendrix, Suzanne B; Soininen, H; van Hees, AMJ; Ellison, N; Visser, PJ; Solomon, A; Attali, A; Blennow, K; Kivipelto, M; Hartmann, T. The Journal of Prevention of Alzheimer's Disease 6 4: 232-236. 2019
FINGER-elintapaohjelma -toimintamalli kognitiivisen toimintakyvyn tukemiseen
Kivipelto, Miia; Kulmala, Jenni; Lehtisalo, Jenni; Solomon, Alina; Lindström, Jaana; Rauramaa, Rainer; Peltonen, Markku; Laatikainen, Tiina; Havulinna, Satu; Soininen, Hilkka; Tuomilehto, Jaakko; Hänninen, Tuomo; Paajanen, Teemu; Antikainen, Riitta; Strandberg, Timo; Ngandu, Tiia. Lääkärilehti 74 4: 183-186. 2019
The Effect of Multidomain Lifestyle Intervention on Daily Functioning in Older People
Kulmala, J; Ngandu, T; Havulinna, S; Levälahti, E; Lehtisalo, J; Solomon, A; Antikainen, R; Laatikainen, T; Pippola, P; Peltonen, M; Rauramaa, R; Soininen, H; Strandberg, T; Tuomilehto, J; Kivipelto, M. Journal of the american geriatrics society 67 6: 1138-1144. 2019
Predicting Development of Alzheimer's Disease in Patients with Shunted Idiopathic Normal Pressure Hydrocephalus
Luikku, AJ; Hall, A; Nerg, O; Koivisto, AM; Hiltunen, M; Helisalmi, S; Herukka, SK; Junkkari, A; Sutela, A; Kojoukhova, M; Korhonen, V; Mattila, J; Lötjönen, J; Rummukainen, J; Alafuzoff, I; Jääskeläinen, JE; Remes, AM; Solomon, A; Kivipelto, M; Soininen, H; et al. [Incl. Rauramaa, T; Leinonen, V]. Journal of Alzheimer's disease 71 4: 1233-1243. 2019
Multidomain Interventions to Prevent Cognitive Impairment, Alzheimer's Disease, and Dementia: From FINGER to World-Wide FINGERS
Rosenberg, A; Mangialasche, F; Ngandu, T; Solomon, A; Kivipelto, M. The Journal of Prevention of Alzheimer's Disease 2020; 7 1: 29-36. 2019
Progression to dementia in memory clinic patients with mild cognitive impairment and normal ß-amyloid
Rosenberg, A; Solomon, A; Jelic, V; Hagman, G; Bogdanovic, N; Kivipelto, M. Alzheimer's research and therapy 11: 99. 2019
European Prevention of Alzheimer's Dementia Longitudinal Cohort Study (EPAD LCS): study protocol
Solomon, A; Kivipelto, M; Molinuevo, JL; Tom, B; Ritchie, CW. BMJ open 8 12: e021017. 2019
Brain volumes and cortical thickness on MRI in the Finnish Geriatric Intervention Study to Prevent Cognitive Impairment and Disability (FINGER)
Stephen, R; Liu, Y; Ngandu, T; Antikainen, R; Hulkkonen, J; Koikkalainen, J; Kemppainen, N; Lötjönen, J; Levälahti, E; Parkkola, R; Pippola, P; Rinne, J; Strandberg, T; Tuomilehto, J; Vanninen, R; Kivipelto, M; Soininen, H; Solomon, A. Alzheimer's research and therapy 11: 53. 2019
CAIDE dementia risk score, Alzheimer and cerebrovascular pathology: a population-based autopsy study
Hooshmand, B; Polvikoski, T; Kivipelto, M; Tanskanen, M; Myllykangas, L; Mäkelä, M; Oinas, M; Paetau, A; Solomon, A. JOURNAL OF INTERNAL MEDICINE 283 6: 597-603. 2018
Decreased plasma C-reactive protein levels in APOE E 4 allele carriers
Martiskainen, Henna; Takalo, Mari; Solomon, Alina; Stancáková, Alena; Marttinen, Mikael; Natunen, Teemu; Haapasalo, Annakaisa; Herukka, Sanna-Kaisa; Kuusisto, Johanna; Soininen, Hilkka; Kivipelto, Miia; Laakso, Markku; Hiltunen, Mikko. Annals of Clinical and Translational Neurology 5 10: 1229-1240. 2018
Multidomain lifestyle intervention benefits a large elderly population at risk for cognitive decline and dementia regardless of baseline characteristics: The FINGER trial
Rosenberg, A; Ngandu, T; Rusanen, M; Antikainen, R; Bäckman, L; Havulinna, S; Hänninen, T; Laatikainen, T; Lehtisalo, J; Levälahti, E; Lindström, J; Paajanen, T; Peltonen, M; Soininen, H; Stigsdotter-Neely, A; Strandberg, T; Tuomilehto, J; Solomon, A; Kivipelto, M. Alzheimer's & Dementia 14 3: 263-270. 2018
Sleep disturbances and later cognitive status: a multi-centre study
Sindi, S; Johansson, L; Skoog, J; Mattsson, AD; Sjöberg, L; Wang, HX; Fratiglioni, L; Kulmala, J; Soininen, H; Solomon, A; Johansson, B; Skoog, I; Kivipelto, M; Kåreholt, I. SLEEP MEDICINE 52: 26-33. 2018
Sleep disturbances and dementia risk: A multicenter study
Sindi, S; Kåreholt, I; Johansson, L; Skoog, J; Sjöberg, L; Wang, HX; Johansson, B; Fratiglioni, L; Soininen, H; Solomon, A; Skoog, I; Kivipelto, M. Alzheimer's & Dementia 14 10: 1235-1242. 2018
Effect of the Apolipoprotein E Genotype on Cognitive Change During a Multidomain Lifestyle Intervention: A Subgroup Analysis of a Randomized Clinical Trial
Solomon, A; Turunen, H; Ngandu, T; Peltonen, M; Levälahti, E; Helisalmi, S; Antikainen, R; Bäckman, L; Hänninen, T; Jula, A; Laatikainen, T; Lehtisalo, J; Lindström, J; Paajanen, T; Pajala, S; Stigsdotter-Neely, A; Strandberg, T; Tuomilehto, J; Soininen, H; Kivipelto, M. JAMA neurology 75 4: 462-470. 2018
Tutkimusnäytöstä kohti uusia käytäntöjä: Liikunta- ja elintapamuutoksilla muistisairauksia ehkäisemään
Kulmala Jenni, Rosenberg Anna, Ngandu Tiia, Solomon Alina, Kivipelto Miia. LIIKUNTA JA TIEDE 54 4: 17-21. 2017
Hippocampal Sclerosis and Epilepsy in Elderly Population
Rauramaa Tuomas, Solomon Alina, Pikkarainen Maria, Kälviäinen Reetta, Alafuzoff Irina. Journal of Alzheimers Disease & Parkinsonism 7 5: 384. 2017
Baseline Telomere Length and Effects of a Multidomain Lifestyle Intervention on Cognition: The FINGER Randomized Controlled Trial
Sindi Shireen, Ngandu Tiia, Hovatta Iiris, Kåreholt Ingemar, Antikainen Riitta, Hänninen Tuomo, Levälahti Esko, Laatikainen Tiina, Lindström Jaana, Paajanen Teemu, Peltonen Markku, Khalsa Dharma Singh, Wolozin Benjamin, Strandberg Timo, Tuomilehto Jaakko, Soininen Hilkka, Kivipelto Miia, Solomon Alina. Journal of Alzheimer's Disease 59 4: 1459-1470. 2017
Midlife Work-Related Stress is Associated with Late-Life Gray Matter Volume Atrophy
Sindi, Shireen; Kåreholt, Ingemar; Spulber, Gabriela; Soininen, Hilkka; Kivipelto, Miia; Solomon, Alina. Journal of Alzheimer's Disease Reports 1 1: 219-227. 2017
24-month intervention with a specific multinutrient in people with prodromal Alzheimer's disease (LipiDiDiet): a randomised, double-blind, controlled trial
Soininen Hilkka, Solomon Alina, Jelle Visser Pieter, Hendrix Suzanne B, Blennow Kaj, Kivipelto Miia, Hartmann Tobias, LipiDiDiet clinical study group. LANCET NEUROLOGY 16 12: 965-975. 2017
Self-rated physical fitness and estimated maximal oxygen uptake in relation to all-cause and cause-specific mortality
Solomon A, Borodulin, Ngandu T, Kivipelto M, Laatikainen T, Kulmala J. SCANDINAVIAN JOURNAL OF MEDICINE & SCIENCE IN SPORTS 2018; 28 2: 532-540. 2017
Associations of CAIDE Dementia Risk Score with MRI, PIB-PET measures, and cognition
Stephen R, Liu Y, Ngandu T, Rinne JO, Kemppainen N, Parkkola R, Laatikainen T, Paajanen T, Hänninen T, Strandberg T, Antikainen R, Tuomilehto J, Keinänen Kiukaanniemi S, Vanninen R, Helisalmi S, Levälahti E, Kivipelto M, Soininen H, Solomon A. Journal of Alzheimer's Disease 59 2: 695-705. 2017
Physical Activity and Alzheimer's Disease: A Systematic Review
Stephen Ruth, Hongisto Kristiina, Solomon Alina, Lönnroos Eija. JOURNALS OF GERONTOLOGY. SERIES A, BIOLOGICAL SCIENCES AND MEDICAL SCIENCES 72 6: 733-739. 2017
Health-related quality of life in a multidomain intervention trial to prevent cognitive decline (FINGER)
Strandberg TE, Levälahti E, Ngandu T, Solomon A, Kivipelto M, Lehtisalo J, Laatikainen T, Soininen H, Antikainen R, Jula A, Tuomilehto J, Peltonen M, Lindström J, Rauramaa R, Pajala S, Hänninen T, Solomon A, Paajanen T, Mangialasche F, FINGER Study Group. European Geriatric Medicine 8 2: 164-167. 2017
CAIDE Dementia Risk Score and biomarkers of neurodegeneration in memory clinic patients without dementia.
Enache D, Solomon A, Cavallin L, Kåreholt I, Kramberger MG, Aarsland D, Kivipelto M, Eriksdotter M, Winblad B, Jelic V. NEUROBIOLOGY OF AGING 42: 124-131. 2016
Association of Vitamin B12, Folate, and Sulfur Amino Acids With Brain Magnetic Resonance Imaging Measures in Older Adults: A Longitudinal Population-Based Study
Hooshmand B, Mangialasche F, Kalpouzos G, Solomon A, Kåreholt I, Smith AD, Refsum H, Wang R, Mühlmann M, Ertl-Wagner B, Laukka EJ, Bäckman L, Fratiglioni L, Kivipelto M. JAMA Psychiatry 73 6: 606-613. 2016
Estradiol and Cognition in the Cardiovascular Risk Factors, Aging and Dementia (CAIDE) Cohort Study
Imtiaz Bushra, Tolppanen Anna-Maija, Solomon Alina, Soininen Hilkka, Kivipelto Miia. Journal of Alzheimer's Disease 2017; 56 2: 453-458. 2016
Development of a Late-Life Dementia Prediction Index with Supervised Machine Learning in the Population-Based CAIDE Study
Pekkala Timo, Hall Anette, Lötjönen Jyrki, Mattila Jussi, Soininen Hilkka, Ngandu Tiia, Laatikainen Tiina, Kivipelto Miia, Solomon Alina. Journal of Alzheimer's Disease 2017; 55 3: 1055-1067. 2016
Midlife work-related stress increases dementia risk in later life: the CAIDE 30-year study
Sindi Shireen, Hagman Göran, Håkansson Krister, Kulmala Jenni, Nilsen Charlotta, Kåreholt Ingemar, Soininen Hilkka, Solomon Alina, Kivipelto Miia. The journals of gerontology. Series B, Psychological sciences and social sciences 2017; 72 6: 1044-1053. 2016
Pointing the FINGER at multimodal dementia prevention - Authors' reply
Kivipelto Miia, Mangialasched Francesca, Solomon Alina on behalf of the FINGER Study Group. LANCET 386 10004: 1627. 2015
A 2 year multidomain intervention of diet, exercise, cognitive training, and vascular risk monitoring versus control to prevent cognitive decline in at-risk elderly people (FINGER): a randomised controlled trial
Ngandu Tiia, Lehtisalo Jenni, Solomon Alina, Levälahti Esko, Ahtiluoto Satu, Antikainen Riitta, Bäckman Lars, Hänninen Tuomo, Jula Antti, Laatikainen Tiina, Lindström Jaana, Mangialasche Francesca, Paajanen Teemu, Pajala Satu, Peltonen Markku, Rauramaa Rainer, Stigsdotter-Neely Anna, Strandberg T, Tuomilehto J, Soininen Hilkka, Kivipelto Miia. LANCET 385 9984: 2255-2263. 2015
Dementia: Risk prediction models in dementia prevention
Solomon Alina, Soininen Hilkka. Nature Reviews Neurology 11: 375-377. 2015
Midlife CAIDE Dementia Risk Score and Dementia-Related Brain Changes up to 30 Years Later on Magnetic Resonance Imaging
Vuorinen Miika, Spulber Gabriela, Soheil Damingir, Niskanen Eini, Ngandu Tiia, Soininen Hilkka, Kivipelto Miia, Soloman Alina. Journal of Alzheimer's Disease 44 1: 93-101. 2015
Vitamin D in relation to cognitive impairment, cerebrospinal fluid biomarkers, and brain volumes
Hooshmand Babak, Lökk Johan, Solomon Alina, Mangialasche Francesca, Miralbell Julia, Spulber Gabriela, Annerbo Sylvia, Andreasen Niels, Winblad Bengt, Cedazo-Minguez Angel, Wahlund Lars-Olof, Kivipelto Miia. JOURNALS OF GERONTOLOGY. SERIES A, BIOLOGICAL SCIENCES AND MEDICAL SCIENCES - 2014 Feb 25. [Epub ahead of print]: 7 s.. 2014
9th Key symposium introduction: Updating Alzheimer's disease diagnosis implications for prevention and treatment
Kivipelto M, Mangialasche F, Solomon A, Johansson G, Lannfelt L, Fratiglioni L, Winblad B. JOURNAL OF INTERNAL MEDICINE 275: 202-203. 2014
Association between mid- to late life physical fitness and dementia: evidence from the CAIDE study
Kulmala J, Solomon A, Kåreholt I, Ngandu T, Rantanen T, Laatikainen T, Soininen H, Tuomilehto J, Kivipelto M. JOURNAL OF INTERNAL MEDICINE 276 3: 296-307. 2014
Late-life cynical distrust, risk of incident dementia, and mortality in a population-based cohort
Neuvonen Elisa, Rusanen Minna, Solomon Alina, Ngandu Tiia, Laatikainen Tiina, Soininen Hilkka, Kivipelto Miia, Tolppanen Anna-Maija. NEUROLOGY 82: 2205-2212. 2014
Recruitment and baseline characteristics of participants in the Finnish Geriatric Intervention Study to Prevent Cognitive Impairment and Disability (FINGER)-a randomized controlled lifestyle trial
Ngandu Tiia, Lehtisalo Jenni, Levälahti Esko, Laatikainen Tiina, Lindström Jaana, Peltonen Markku, Solomon Alina, Ahtiluoto Satu, Antikainen Riitta, Hänninen Tuomo, Jula Antti, Mangialasche Francesca, Paajanen Teemu, Pajala Satu, Rauramaa Rainer, Strandberg Timo, Tuomilehto Jaakko, Soininen Hilkka, Kivipelto Miia. International Journal of Environmental Research and Public Health 11 9: 9345-9360. 2014
Advances in the prevention of Alzheimer's disease and dementia
Solomon A, Mangialasche F, Richard E, Andrieu S, Bennett DA, Breteler B, Fratiglioni L, Hooshmand B, Khachaturian AS, Schneider LS, Skoog I, Kivipelto M. JOURNAL OF INTERNAL MEDICINE 275 3: 229-250. 2014
Leisure-time physical activity from mid- to late life, body mass index, and risk of dementia
Tolppanen Anna-Maija, Solomon Alina, Kulmala Jenni, Kåreholt Ingemar, Ngandu Tiia, Rusanen Minna, Laatikainen Tiina, Soininen Hilkka, Kivipelto Miia. Alzheimer's & Dementia Epub ahead of print: -. 2014
Coronary Heart Disease and Cortical Thickness, Gray Matter and White Matter Lesion Volumes on MRI
Vuorinen Miika, Damangir Soheil, Niskanen Eini, Miralbell Julia, Rusanen Minna, Spulber Gabriela, Soininen Hilkka, Kivipelto Miia, Solomon Alina. PLOS ONE [ONLINE] 9 10: e109250, 1-9. 2014
Plasma homocysteine, Alzheimer and cerebrovascular pathology: a population-based autopsy study
Hooshmand B, Polvikoski T, Kivipelto M, Tanskanen M, Myllykangas L, Erkinjuntti T, Mäkelä M, Oinas M, Paetau A, Scheltens P, van Straaten ECW, Sulkava R, Solomon A. BRAIN 136: 2707-2716. 2013
The Finnish Geriatric intervention study to prevent cognitive impairment and disability (FINGER): Study design and progress
Kivipelto M, Solomon A, Ahtiluoto S, Ngandu T, Lehtisalo J, Antikainen R, Bäckman L, Hänninen T, Jula A, Laatikainen T, Lindström J, Mangialasche F, Nissinen A, Paajanen T, Pajala S, Peltonen M, Rauramaa R, Stigsdotter-Neely A, Strandberg T, Tuomilehto J, Soininen H. Alzheimer's & Dementia 9 6: 657-665. 2013
Diagnostic power of 24S-hydroxycholesterol in cerebrospinal fluid: Candidate marker of brain health
Leoni V, Solomon A, Lövgren-Sandholm A, Blennow K, Hansson O, Wahlund L-O, Kivipelto M, Björkhem I. Journal of Alzheimer's Disease 36: 739-747. 2013
Serum levels of vitamin E forms and risk of cognitive impairment in a Finnish cohort of older adults
Mangialasche F, Solomon A, Kåreholt I, Hooshmand B, Cecchetti R, Fratiglioni L, Soininen H, Laatikainen T, Mecocci P, Kivipelto M. EXPERIMENTAL GERONTOLOGY 48: 1428-1435. 2013
Prevention of Alzheimer's Disease: Moving backward through the lifespan
Solomon A, Kivipelto M, Soininen H. Journal of Alzheimer's Disease 33: S465-S469. 2013
Cholesterol, statins, and late-life cognitive disorders.
Solomon A, Kivipelto M. Yaffe Kristine, Chronic Medical Disease and Cognitive Aging. Toward a healthy body and brain. 13-39. 2013
Validity of dementia and Alzheimer disease diagnoses in Finnish national registers
Solomon A, Ngandu T, Soininen H, Hallikainen M, Kivipelto M, Laatikainen T. Alzheimer's & Dementia Epub: 1-7. 2013
Incidence of stroke in people with Alzheimer disease. A national register-based approach
Tolppanen Anna-Maija, Lavikainen Piia, Solomon Alina, Kivipelto Miia, Soininen Hilkka, Hartikainen Sirpa. NEUROLOGY 80 4: 353-358. 2013
History of medically treated diabetes and risk of Alzheimer disease in a nationwide case-control study
Tolppanen Anna-Maija, Lavikainen Piia, Solomon Alina, Kivipelto Miia, Uusitupa Matti, Soininen Hilkka, Hartikainen Sirpa. DIABETES CARE 36: 2015-2019. 2013
Changes in vascular factors 28 years from midlife and late-life cortical thickness
Vuorinen M, Kåreholt I, Julkunen V, Spulber G, Niskanen E, Paajanen T, Soininen H, Kivipelto M, Solomon A. Neurobiology of aging 34: 100-109. 2013
Differences in brain cholestero metabolism and insulin in two subgroups of patients with different CSF biomarkers but similar white matter lesions suggest different pathogenic mechanisms
Besga A, Cedazo-Minguez A, Kåreholt I, Solomon A, Björkhem I, Winblad B, Leoni V, Hooshmand B, Spulber G, Gonzales-Pinto A, Kivipelto M, Wahlund LO. NEUROSCIENCE LETTERS 510 2: 121-126. 2012
Associations between serum homocysteine, holotranscobalamin, folate and cognition in the elderly: a longitudinal study
Hooshmand B, Solomon A, Kåreholt I, Rusanen M, Hänninen T, Leivistä J, Winblad B, Laatikainen T, Soininen H, Kivipelto M. JOURNAL OF INTERNAL MEDICINE 271: 204-212. 2012
Dementia prevention: current epidemiological evidence and future perspective
Mangialasche F, Kivipelto M, Solomon M, Fratiglioni L. Alzheimer's research and therapy 4 6: 1-8. 2012
Methodological challenges in designing dementia prevention trials - The European Dementia Prevention Initiative (EDPI)
Richard E, Andrieu S, Solomon A, Mangialasche F, Ahtiluoto S, Moll van Charante EP, Coley N, Fratiglioni L, Stigsdotter Neely A, Vellas B, van Gool WA, Kivipelto M. JOURNAL OF THE NEUROLOGICAL SCIENCES 322: 64-70. 2012
Practical Lessons from Amyloid Immunotherapy Trials in Alzheimer Disease
Solomon A, Akenine U, Andreasen N, Mangialasche F, Wimo A, Jelic V, Kivipelto M, Winblad B. CURRENT ALZHEIMER RESEARCH 9: 1126-1134. 2012
Midlife Vascular Risk Factors and Alzheimer's Disease: Evidence from Epidemiological Studies
Tolppanen AM, Solomon A, Soininen H, Kivipelto M. Journal of Alzheimer's Disease 32 3: 531-40. 2012
Midlife rheumatoid arthritis increases the risk of cognitive impairment two decades later: A population-based study
Wallin K, Solomon A, Kåreholt I, Tuomilehto J, Soininen H, Kivipelto M. Journal of Alzheimer's Disease 31: 669-676. 2012
IAGG Workshop: Health promotion program on prevention of late onset dementia
Andrieu S, Aboderin I, Baeyens J-P, Beard J, Benetos A, Berrut G, Brainin M, Cha HB, Chen L-K, Forette B, Forette F, Franco A, Fratigkioni L, Gillette-Guyonnet S, Gold G, Gomez F, Guimaraes R, Gustafson D, Khachaturian A, Luchsinger J, Mangialasche F, Mathiex-Fortunet H, Michel J-P, Richard E, Schneider LS, Solomon A, Vellas B. JOURNAL OF NUTRITION, HEALTH & AGING 15: 562-575. 2011
Comorbidity and the rate of cognitive decline in patients with Alzheimer dementia
Solomon A, Dobranici L, Kåreholt I, Tudose C, Lazarescu M. INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY 26: 1244-1251. 2011
Changes in vascular risk factors from midlife to late life and white matter lesions: A 20-year follow-up study
Vuorinen Miika, Solomon Alina, Rovio Suvi, Nieminen Lasse, Kåreholt Ingemar, Tuomilehto Jaakko, Soininen Hilkka, Kivipelto Miia. DEMENTIA AND GERIATRIC COGNITIVE DISORDERS 31: 119-125. 2011
Cost-effectiveness of a health intervention program with risk reductions for getting demented: Results of a Markow model in a Swedish/Finnish setting
Zhang Y, Kivipelto M, Solomon A, Wimo A. Journal of Alzheimer's Disease 26: 735-744. 2011
Diabetes, Alzheimer disease, and vascular dementia: a population-based neuropathologic study
Ahtiluoto S, Polvikoski T, Peltonen M, Solomon A, Tuomilehto J, Winblad B, Sulkava R & Kivipelto M. NEUROLOGY 75 13: 1195-1202. 2010
Homocysteine and holotranscobalamin and the risk of Alzheimer disease
Hooshmand B, Solomon A, Kåreholt I, Leivistä J, Rusanen M, Ahtiluoto S, Winblad B, Laatikainen T, Soininen H & Kivipelto M. NEUROLOGY 75: 1408-1414. 2010
Links between ApoE, brain cholesterol metabolism, tau and amyloid beeta-peptide in patients with cognitive impairment
Leoni V, Solomon A & Kivipelto M. BIOCHEMICAL SOCIETY TRANSACTIONS 38: 1021-2025. 2010
Alzheimer's disease: clinical trials and drug development
Mangialasche F, Solomon A, Winblad B, Mecocci P & Kivipelto M. LANCET NEUROLOGY 9: 702-16. 2010
Lipid-Lowering Treatment Is Related to Decreased Risk of Dementia: A Population-Based Study (FINRISK)
Solomon A, Sippola R, Soininen H, Wolozin B, Tuomilehto J, Laatikainen T & Kivipelto M. NEURODEGENERATIVE DISEASES 7: 180-182. 2010
Midlife serum cholesterol and increased risk of Alzheimer's and vascular dementia three decades later
Solomon A, Kivipelto M, Wolozin B, Zhou J, Whitmer RA. DEMENTIA AND GERIATRIC COGNITIVE DISORDERS 28: 75-80. 2009
Cholesterol and Late-Life Cognition. An Epidemiological and Clinical Approach
Solomon A. Kuopion yliopisto. Neurologian klinikan julkaisusarja, No. 2009
Levels of ApoE in cerebrospinal fluid are correlated with Tau and 24S-hydroxycholesterol in patients with cognitive disorders
Shafaati M, Solomon A, Kivipelto M, Björkhem I, Leoni V. NEUROSCIENCE LETTERS 425: 78-82. 2007
Serum cholesterol changes after midlife and late-life cognition. Twenty-one-year follow-up study
Solomon A, Kåreholt I, Ngandu T, Winblad B, Nissinen A, Tuomilehto J, Soininen H, Kivipelto M. NEUROLOGY 68: 751-756. 2007
The new cholesterol controversy - a little bit of history repeating?
Kivipelto M, Solomon A, Blennow K, Olsson AG, Winblad B. ACTA NEUROLOGICA SCANDINAVICA. SUPPLEMENTUM 114 185: 1-2. 2006
Alzheimer's Disease: back to the future
Kivipelto M, Solomon A, Winbland B. ACTA NEUROLOGICA SCANDINAVICA. SUPPLEMENTUM 114 185: 119-120. 2006
Cerebral embolism and Alzheimer¿s disease
Kivipelto M, Solomon A. BMJ (COMPACT) 332: 1104-1105. 2006
Cholesterol as a risk factor for Alzheimer¿s disease - epidemiological evidence
Kivipelto M, Solomon A. ACTA NEUROLOGICA SCANDINAVICA. SUPPLEMENTUM 114 185: 50-57. 2006

University of Eastern Finland Joensuu, Kuopio © University of Eastern Finland

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Näytä asetukset

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Alina Solomon

Tutkimusryhmät

Projektit

Quantifying dementia prevention potential in the FINGER randomized controlled trial using the LIBRA prevention index.

Facilitators and barriers to implementing lifestyle intervention programme to prevent cognitive decline

Personal Social Networks of Community-Dwelling Oldest Old During the Covid-19 Pandemic - A Qualitative Study

Changes in Lifestyle, Behaviors, and Risk Factors for Cognitive Impairment in Older Persons During the First Wave of the Coronavirus Disease 2019 Pandemic in Finland: Results From the FINGER Study

The effect of adherence on cognition in a multidomain lifestyle intervention (FINGER)

Research diagnostic criteria for Alzheimer's disease: findings from the LipiDiDiet randomized controlled trial

27-Hydroxycholesterol, cognition, and brain imaging markers in the FINGER randomized controlled trial

Telomere length change in a multidomain lifestyle intervention to prevent cognitive decline: a randomized clinical trial

Effect of a Multidomain Lifestyle Intervention on Estimated Dementia Risk

Multidomain interventions: state-of-the-art and future directions for protocols to implement precision dementia risk reduction. A user manual for Brain Health Services-part 4 of 6

Development of the First WHO Guidelines for Risk Reduction of Cognitive Decline and Dementia: Lessons Learned and Future Directions

Change in CAIDE Dementia Risk Score and neuroimaging biomarkers during a 2-year multidomain lifestyle randomized controlled trial: results of a post-hoc subgroup analysis

Everyday Life Meaningfulness for the Community-Dwelling Oldest Old During the COVID-19 Pandemic

Third follow-up of the Cardiovascular Risk Factors, Aging and Dementia (CAIDE) cohort investigating determinants of cognitive, physical, and psychosocial wellbeing among the oldest old: the CAIDE85+ study protocol

World-Wide FINGERS Network: A global approach to risk reduction and prevention of dementia

Late-life personality traits, cognitive impairment, and mortality in a population-based cohort

Association of Peripheral Insulin Resistance and Other Markers of Type 2 Diabetes Mellitus With Brain Amyloid Deposition in Healthy Individuals at Risk of Dementia

Detecting Amyloid Positivity in Elderly With Increased Risk of Cognitive Decline

White Matter Changes on Diffusion Tensor Imaging in the FINGER Randomized Controlled Trial

Prescreening for European Prevention of Alzheimer Dementia (EPAD) trial-ready cohort: impact of AD risk factors and recruitment settings

Long-term dementia risk prediction by the LIBRA score: a 30-year follow-up of the CAIDE study

From prediction to dementia prevention

Prediction models for dementia and neuropathology in the oldest old: the Vantaa 85+ cohort study

Alzheimer's Disease Composite Score: A Post-Hoc Analysis Using Data from the LipiDiDiet Trial in Prodromal Alzheimer's Disease

FINGER-elintapaohjelma -toimintamalli kognitiivisen toimintakyvyn tukemiseen

The Effect of Multidomain Lifestyle Intervention on Daily Functioning in Older People

Predicting Development of Alzheimer's Disease in Patients with Shunted Idiopathic Normal Pressure Hydrocephalus

Multidomain Interventions to Prevent Cognitive Impairment, Alzheimer's Disease, and Dementia: From FINGER to World-Wide FINGERS

Progression to dementia in memory clinic patients with mild cognitive impairment and normal ß-amyloid

European Prevention of Alzheimer's Dementia Longitudinal Cohort Study (EPAD LCS): study protocol

Brain volumes and cortical thickness on MRI in the Finnish Geriatric Intervention Study to Prevent Cognitive Impairment and Disability (FINGER)

CAIDE dementia risk score, Alzheimer and cerebrovascular pathology: a population-based autopsy study

Decreased plasma C-reactive protein levels in APOE E 4 allele carriers

Multidomain lifestyle intervention benefits a large elderly population at risk for cognitive decline and dementia regardless of baseline characteristics: The FINGER trial

Sleep disturbances and later cognitive status: a multi-centre study

Sleep disturbances and dementia risk: A multicenter study

Effect of the Apolipoprotein E Genotype on Cognitive Change During a Multidomain Lifestyle Intervention: A Subgroup Analysis of a Randomized Clinical Trial

Tutkimusnäytöstä kohti uusia käytäntöjä: Liikunta- ja elintapamuutoksilla muistisairauksia ehkäisemään

Hippocampal Sclerosis and Epilepsy in Elderly Population

Baseline Telomere Length and Effects of a Multidomain Lifestyle Intervention on Cognition: The FINGER Randomized Controlled Trial

Midlife Work-Related Stress is Associated with Late-Life Gray Matter Volume Atrophy

24-month intervention with a specific multinutrient in people with prodromal Alzheimer's disease (LipiDiDiet): a randomised, double-blind, controlled trial

Self-rated physical fitness and estimated maximal oxygen uptake in relation to all-cause and cause-specific mortality

Associations of CAIDE Dementia Risk Score with MRI, PIB-PET measures, and cognition

Physical Activity and Alzheimer's Disease: A Systematic Review

Health-related quality of life in a multidomain intervention trial to prevent cognitive decline (FINGER)

CAIDE Dementia Risk Score and biomarkers of neurodegeneration in memory clinic patients without dementia.

Association of Vitamin B12, Folate, and Sulfur Amino Acids With Brain Magnetic Resonance Imaging Measures in Older Adults: A Longitudinal Population-Based Study

Estradiol and Cognition in the Cardiovascular Risk Factors, Aging and Dementia (CAIDE) Cohort Study

Development of a Late-Life Dementia Prediction Index with Supervised Machine Learning in the Population-Based CAIDE Study

Midlife work-related stress increases dementia risk in later life: the CAIDE 30-year study

Pointing the FINGER at multimodal dementia prevention - Authors' reply

A 2 year multidomain intervention of diet, exercise, cognitive training, and vascular risk monitoring versus control to prevent cognitive decline in at-risk elderly people (FINGER): a randomised controlled trial

Dementia: Risk prediction models in dementia prevention

Midlife CAIDE Dementia Risk Score and Dementia-Related Brain Changes up to 30 Years Later on Magnetic Resonance Imaging

Vitamin D in relation to cognitive impairment, cerebrospinal fluid biomarkers, and brain volumes

9th Key symposium introduction: Updating Alzheimer's disease diagnosis implications for prevention and treatment

Association between mid- to late life physical fitness and dementia: evidence from the CAIDE study

Late-life cynical distrust, risk of incident dementia, and mortality in a population-based cohort

Recruitment and baseline characteristics of participants in the Finnish Geriatric Intervention Study to Prevent Cognitive Impairment and Disability (FINGER)-a randomized controlled lifestyle trial

Advances in the prevention of Alzheimer's disease and dementia

Leisure-time physical activity from mid- to late life, body mass index, and risk of dementia

Coronary Heart Disease and Cortical Thickness, Gray Matter and White Matter Lesion Volumes on MRI

Plasma homocysteine, Alzheimer and cerebrovascular pathology: a population-based autopsy study

The Finnish Geriatric intervention study to prevent cognitive impairment and disability (FINGER): Study design and progress

Diagnostic power of 24S-hydroxycholesterol in cerebrospinal fluid: Candidate marker of brain health

Serum levels of vitamin E forms and risk of cognitive impairment in a Finnish cohort of older adults

Prevention of Alzheimer's Disease: Moving backward through the lifespan

Cholesterol, statins, and late-life cognitive disorders.

Validity of dementia and Alzheimer disease diagnoses in Finnish national registers

Incidence of stroke in people with Alzheimer disease. A national register-based approach

History of medically treated diabetes and risk of Alzheimer disease in a nationwide case-control study

Changes in vascular factors 28 years from midlife and late-life cortical thickness

Differences in brain cholestero metabolism and insulin in two subgroups of patients with different CSF biomarkers but similar white matter lesions suggest different pathogenic mechanisms

Associations between serum homocysteine, holotranscobalamin, folate and cognition in the elderly: a longitudinal study

Dementia prevention: current epidemiological evidence and future perspective

Methodological challenges in designing dementia prevention trials - The European Dementia Prevention Initiative (EDPI)