Anna-Maija Tolppanen
Professori
Toimin hoidon vaikuttavuuden professorina.Opetan lääke-epidemiologiaa ja johdan monitieteellistä,ulkopuolisella rahoituksella toimivaa tutkimusryhmää.Tutkimme hoidon vaikuttavuutta perinteisen tilastotieteen ja tiedonlouhinnan menetelmin.
Farmasian laitos, Terveystieteiden tiedekunta
anna-maija.tolppanen@uef.fi | 050 575 9530
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050 5759530
050 575 9530
+358 50 575 9530
+35850 575 9530
050 5759 530
+358 50 5759 530
+35850 5759 530
+358 50 5759530
+35850 5759530
+358505759530
Tutkimusryhmät
Projektit
Julkaisut
188 kappaletta-
Agreement between physician- and patient-reported Canadian cardiovascular society scores among patients undergoing elective coronary angiography–The CATS study
Lavikainen, Piia; Hartikainen, Juha; Miettinen, Heikki; Viljakainen, Marketta; Martikainen, Janne; Tolppanen, Anna-Maija; Roine, Risto P. 2023. PLoS ONE. 18: -
Association of Personal Wealth Indicators and Health Care Costs in Persons With Alzheimer's Disease
Jarroch, Rand; Hartikainen, Sirpa; Kauhanen, Jussi; Knapp, Martin; Tolppanen, Anna-Maija. 2023. Journal of the american medical directors association. 24: 1974-1980 -
Diagnostic groups of hospital stays and outpatient visits during 10 years before Alzheimer’s disease
Mäklin, Kiira; Lampela, Pasi; Lin, Julian; Sirpa, Hartikainen; Tolppanen, Anna-Maija. 2023. Bmc health services research. 23: . 339 -
Finding Answers
Tolppanen, Anna-Maija. 2023. JAMA : Journal of the American Medical Association. 329: 709-710 -
Global epidemiology of hip fractures: secular trends in incidence rate, post‐fracture treatment, and all‐cause mortality
Sing, Chor‐Wing; Lin, Tzu‐Chieh; Bartholomew, Sharon; J, Simon Bell; Bennett, Corina; Beyene, Kebede; Bosco‐Levy, Pauline; Bradbury, Brian D; Chan, Amy Hai Yan; Chandran, Manju; Cooper, Cyrus; de Ridder, Maria; Y, Caroline Doyon; Droz‐Perroteau, Cécile; Ganesan, Ganga; Hartikainen, Sirpa; Ilomaki, Jenni; Jeong, Han Eol; Kiel, Douglas P; Kubota, Kiyoshi; Chia‐Cheng Lai, Edward; Lange, Jeff L; Lewiecki, E Michael; Lin, Julian; Liu, Jiannong; Maskell, Joe; de Abreu, Mirhelen Mendes; O'Kelly, James;. 2023. Journal of bone and mineral research. 38: 1064-1075 -
Hospitalization and the Risk of Initiation of Antipsychotics in Persons With Parkinson's Disease
Pirttilä, Aki; Tiihonen, Miia; Paakinaho, Anne; Hartikainen, Sirpa; Tolppanen, Anna-Maija. 2023. Journal of the american medical directors association. 24: 1290-1296.e4 -
Letter in response to Cole-Hunter et al., 2023: What does "Parkinson's disease mortality" mean?
Rumrich, Isabell Katharina; Kaasinen, Valtteri; Hänninen, Otto; Hartikainen, Sirpa; Tolppanen, Anna Maija. 2023. Environment international. 173: 107852 -
Long-term exposure to low-level particulate air pollution and Parkinson's disease diagnosis - A Finnish register-based study
Rumrich, Isabell Katharina; Lin, Julian; Korhonen, Antti; Frohn, Lise Marie; Geels, Camilla; Brandt, Jørgen; Hartikainen, Sirpa; Hänninen, Otto; Tolppanen, Anna-Maija. 2023. Environmental research. 229: -
Recent Hospitalization and Initiation of Antiepileptics Among Persons With Alzheimer’s Disease
Elo, Jenna; Tolppanen, Anna-Maija; Koponen, Marjaana; Tiihonen, Miia; Hartikainen, Sirpa. 2023. Journal of the american medical directors association. 24: 213-219.e6 -
Risk factors of pneumonia in persons with and without Alzheimer's disease: a matched cohort study
Järvinen, Heli; Tolppanen, Anna Maija; Hartikainen, Sirpa. 2023. Bmc geriatrics. 23: -
The Cumulative Use of Muscle Relaxants and the Risk of Alzheimer’s Disease: A Nationwide Case-Control Study
Rahkonen, Atte; Taipale, Heidi; Koponen, Marjaana; Hartikainen, Sirpa; Tolppanen, Anna-Maija; Tanskanen, Antti; Tiihonen, Miia. 2023. Journal of Alzheimer's disease. 91: 1283-1290 -
The Incidence and Outcomes of Head Injuries in People with and without Parkinson's Disease
Ilmaniemi, Sarianna; Tolppanen, Anna‐Maija; Herukka, Sanna‐Kaisa; Hartikainen, Päivi; Hartikainen, Sirpa. 2023. European journal of neurology. 30: 1648-1657 -
β2-Adrenoceptor Agonists in Asthma or Chronic Obstructive Pulmonary Disease and Risk of Parkinson’s Disease: Nested Case-Control Study
Paakinaho, Anne; Tiihonen, Miia; Koskela, Heikki; Koponen, Marjaana; Tiihonen, Jari; Hartikainen, Sirpa; Tolppanen, Anna-Maija. 2023. Clinical epidemiology. 15: 695-705 -
Antipsychotic Use and Risk of Stroke Among Community-Dwelling People With Alzheimer's Disease
Koponen, Marjaana; Rajamaki, Blair; Lavikainen, Piia; Bell, J Simon; Taipale, Heidi; Tanskanen, Antti; Hartikainen, Sirpa; Tolppanen, Anna-Maija. 2022. Journal of the american medical directors association. 23: 1059-1065 -
Association between different diabetes medication classes and risk of Parkinson's disease in people with diabetes
Sunnarborg, Katriina; Tiihonen, Miia; Huovinen, Marjo; Koponen, Marjaana; Hartikainen, Sirpa; Tolppanen, Anna‐Maija. 2022. Pharmacoepidemiology and drug safety. 31: 875-882 -
Coronary artery revascularizations and cognitive decline - A systematic review
Lappalainen, Laura; Rajamaki, Blair; Tolppanen, Anna-Maija; Hartikainen, Sirpa. 2022. Current problems in cardiology. 47: -
Correlation of the disease-specific Canadian Cardiovascular Society (CCS) classification and health-related quality of life (15D) in coronary artery disease patients
Kotajärvi, Jarno; Tolppanen, Anna-Maija; Hartikainen, Juha; Miettinen, Heikki; Viljakainen, Marketta; Martikainen, Janne; Roine, Risto P; Lavikainen, Piia. 2022. PLoS ONE. 17: -
Disease-Modifying Antirheumatic Drugs and Risk of Parkinson Disease
Paakinaho, Anne; Koponen, Marjaana; Tiihonen, Miia; Kauppi, Markku; Hartikainen, Sirpa; Tolppanen, Anna-Maija. 2022. Neurology. 98: e1273-e1281 -
Geriatric impairments were directly and indirectly associated with mortality in older patients with cancer: a structural equation analysis
Canouï-Poitrine, Florence; Martinez-Tapia, Claudia; Paillaud, Elena; Mathoulin-Pelissier, Simone; Pamoukdjian, Frédéric; Frasca, Matthieu; Tolppanen, Anna-Maija; Bringuier, Michael; Brain, Etienne; Broussier, Amaury; Bastuji-Garin, Sylvie; Laurent, Marie; Audureau, Etienne. 2022. Journal of clinical epidemiology. 148: 17-26 -
Identification of Drugs Associated with Lower Risk of Parkinson’s Disease Using a Systematic Screening Approach in a Nationwide Nested Case–Control Study
Koponen, Marjaana; Paakinaho, Anne; Lin, Julian; Hartikainen, Sirpa; Tolppanen, Anna-Maija. 2022. Clinical epidemiology. 14: 1217-1227 -
Incidence of antipsychotic use among community dwellers with and without Parkinson's disease
Lilja, Satu; Tolppanen, Anna-Maija; Koponen, Marjaana; Hartikainen, Sirpa; Tiihonen, Miia. 2022. Parkinsonism and related disorders. 103: 69-72 -
Incidence of cataract surgeries in relation to diagnosis of Parkinson's disease
Lampela, Pasi; Tolppanen, Anna-Maija; Kaarniranta, Kai; Hokkinen, Kaisa; Hartikainen, Sirpa. 2022. Archives of gerontology and geriatrics. 2023; 104: -
Kvantitatiiviset tutkimusmenetelmät sosiaalisen median tekstipohjaisten aineistojen tutkimuksen tukena – apteekeista käytävän verkkokeskustelun aihemallinnus Suomi24-keskustelupalstasta
Pylkkö, Eeva; Tolppanen, Anna-Maija; Timonen, Johanna; LIn, Julian. 2022. Dosis. 38: 434-452 -
Prevalence and characteristics of psychiatric morbidity treated in specialized health care in a nationwide cohort of people with newly diagnosed Alzheimer's disease
Alastalo, Aleksi; Tolppanen, Anna‐Maija; Nietola, Miika; Haapea, Marianne; Miettunen, Jouko; Hartikainen, Sirpa; Jääskeläinen, Erika. 2022. Acta psychiatrica scandinavica. 145: 507-516 -
Prevalence of oral anticoagulant use among people with and without Alzheimer’s disease
Ali Babar, Barkat; Vu, Mai; Koponen, Marjaana; Taipale, Heidi; Tanskanen, Antti; Kettunen, Raimo; Tiihonen, Miia; Hartikainen, Sirpa; Tolppanen, Anna-Maija. 2022. Bmc geriatrics. 22: . 464 -
Recent hospitalization and risk of antidepressant initiation in people with Parkinson’s disease
Hämäläinen, Iida; Tiihonen, Miia; Hartikainen, Sirpa; Tolppanen, Anna-Maija. 2022. Bmc geriatrics. 22: . 974 -
Sexual Activity and Dyspareunia After Pelvic Organ Prolapse Surgery: A 5-Year Nationwide Follow-up Study
Wihersaari, Olga; Karjalainen, Päivi; Tolppanen, Anna-Maija; Mattsson, Nina; Nieminen, Kari; Jalkanen, Jyrki. 2022. European urology open science. 45: 81-89 -
Statin discontinuation in persons with and without Alzheimer’s disease
Vu, Mai; Kettunen, Raimo; Tolppanen, Anna-Maija; Hartikainen, Sirpa; Taipale, Heidi. 2022. European journal of clinical pharmacology. 78: 1145-1153 -
Use of α1‐Adrenoceptor Antagonists Tamsulosin and Alfuzosin and The Risk of Alzheimer's Disease
Latvala, Laura; Tiihonen, Miia; Murtola, Teemu J; Hartikainen, Sirpa; Tolppanen, Anna‐Maija. 2022. Pharmacoepidemiology and drug safety. 31: 1110-1120 -
Vaikuttavuuden mittaus voi parantaa potilasturvallisuutta
Heiskanen, Jari; Tolppanen, Anna-Maija; Roine, Risto P . 2022. Lääkärilehti. 77: 594-595 -
Validity of the Finnish Care Register for Social Welfare in a nationwide cohort of people with Alzheimer’s disease
Hyttinen, Virva; Selander, Kirsikka; Tolppanen, Anna-Maija; Väyrynen, Riikka; Mielikäinen, Lasse; Linnosmaa, Ismo; Hartikainen, Sirpa. 2022. Scandinavian journal of public health. [First published online November 7, 2022]: 1-9 -
Association of recent hospitalisation with antidepressant initiation among community dwellers with Alzheimer's disease
Tarvainen, Anniina; Hartikainen, Sirpa; Taipale, Heidi; Tanskanen, Antti; Koponen, Marjaana; Tolppanen, Anna-Maija. 2021. International journal of geriatric psychiatry. 36: 1075-1084 -
Automated multi-dose dispensing in persons with and without Alzheimer's disease - impacts on pharmacotherapy
Vallius, Sanna; Taipale, Heidi; Koponen, Marjaana; Tolppanen, Anna-Maija; Tanskanen, Antti; Hartikainen, Sirpa; Tiihonen, Miia. 2021. European journal of clinical pharmacology. 2022; 78: 513-521 -
Bentsodiatsepiinien käytön suosittaminen iäkkäille on vaarallista
Roitto, Hanna-Maria; Tolppanen, Anna-Maija; Laurila, Jouko; Tiihonen, Miia; Öhman, Hanna Aalto, Ulla; Jämsen, Esa; Hartikainen, Sirpa. 2021. Lääkärilehti. 76: 1215 -
Changes in the use of diabetes drugs among community-dwelling people with Alzheimer's disease
López-Rubio, Carlos; Koponen, Marjaana; Lampela, Pasi; Taipale, Heidi; Tanskanen, Antti; Bell, J. Simon; Tolppanen, Anna-Maija; Hartikainen, Sirpa. 2021. Bmc geriatrics. 21: 701 -
Coronary Revascularization and Postoperative Outcomes in People With and Without Alzheimer's Disease
Vu, Mai; Koponen, Marjaana; Taipale, Heidi; Kettunen, Raimo; Hartikainen, Sirpa; Tolppanen, Anna-Maija. 2021. Journals of gerontology series a: biological sciences and medical sciences. 76: 1524-1530 -
Does Recent Hospitalization Increase Antipsychotic Initiation Among Community Dwellers With Alzheimer's Disease?
Hakala Anna; Tolppanen, Anna-Maija; Koponen, Marjaana; Taipale, Heidi; Tanskanen, Antti; Hartikainen, Sirpa; Tiihonen, Miia. 2021. Journal of the american medical directors association. 22: 1543--547.e3 -
Hip Fracture Risk in Antiepileptic Drug Initiators and Non-Initiators with Alzheimer's Disease
Pisa, Federica; Reinold, Jonas; Lavikainen, Piia; Koponen, Marjaana; Taipale, Heidi; Tanskanen, Antti; Tiihonen, Jari; Hartikainen, Sirpa; Tolppanen, Anna-Maija. 2021. Clinical epidemiology. 13: 295-307 -
Incidence of antidepressant use among community dwellers with and without Parkinson's disease - a nationwide cohort study
Hentilä, Eerik; Tiihonen, Miia; Taipale, Heidi; Hartikainen, Sirpa; Tolppanen, Anna-Maija. 2021. Bmc geriatrics. 21: 202 -
Incidence of cataract surgeries in people with and without Alzheimer's disease
Hokkinen, K; Kaarniranta, K; Jämsen, E; Lampela, P; Hartikainen, S; Tolppanen, AM. 2021. Acta ophthalmologica. 2022; 100: 68-73 -
Increased Risk of Parkinson's Disease in Patients With Schizophrenia Spectrum Disorders
Kuusimäki, Tomi; Al-Abdulrasul, Haidar; Kurki, Samu; Hietala, Jarmo; Hartikainen, Sirpa; Koponen, Marjaana; Tolppanen, Anna-Maija; Kaasinen, Valtteri. 2021. Movement disorders. 36: 1353-1361 -
Patient-reported outcomes in coronary artery disease: the relationship between the standard, disease-specific set by the International Consortium for Health Outcomes Measurement (ICHOM) and the generic health-related quality of life instrument 15D
Lappalainen, Laura; Stenvall, Harriet; Lavikainen, Piia; Miettinen, Heikki; Martikainen, Janne; Sintonen, Harri; Tolppanen, Anna-Maija; Roine, Risto P; Hartikainen, Juha. 2021. Health and quality of life outcomes. 19: 206 -
Pelvic organ prolapse surgery and overactive bladder symptoms - a population-based cohort (FINPOP)
Karjalainen, Päivi K; Tolppanen, Anna-Maija; Mattsson, Nina K; Wihersaari, Olga AE; Jalkanen, Jyrki T; Nieminen, Kari. 2021. International urogynecology journal. 2022; 33: 95-105 -
The effect of comorbidities on survival in persons with Alzheimer's disease: a matched cohort study
Rajamaki, Blair; Hartikainen, Sirpa; Tolppanen, Anna-Maija. 2021. Bmc geriatrics. 21: 173 -
Agreement between patient global impression scale of improvement, pelvic floor distress inventory and 15D in measuring the outcome of pelvic organ prolapse surgery
Mattsson, Nina K; Karjalainen, Päivi; Heikkinen, Anna-Mari; Nieminen, Kari; Jalkanen, Jyrki; Tolppanen, Anna-Maija. 2020. Neurourology and urodynamics. 39: 2171-2178 -
Antiepileptic drug use and mortality among community-dwelling persons with Alzheimer disease
Sarycheva, Tatyana; Lavikainen, Piia; Taipale, Heidi; Tiihonen, Jari; Tanskanen, Antti; Hartikainen, Sirpa; Tolppanen, Anna-Maija. 2020. Neurology. 94: e2099-e2108 -
Application of Healthcare 'Big Data' in CNS Drug Research: The Example of the Neurological and Mental Health Global Epidemiology Network (NeuroGEN)
Ilomäki, J; Bell, JS; Chan, AYL; Tolppanen, AM; Luo, H; Wei, L; Lai, EC; Shin, JY; De Paoli, G; Pajouheshnia, R; Ho, FK; Reynolds, L; Lau, KK; Crystal, S; Lau, WCY; Man, KKC; Brauer, R; Chan, EW; Shen, CY; Kim, JH; et al. [incl. Hartikainen, S; Koponen, M]. 2020. Cns drugs. 34: 897-913 -
Asthma and Chronic Obstructive Pulmonary Disease as a Comorbidity and Association with the Choice of Antidementia Medication Among Persons with Alzheimer's Disease
Lampela, P; Tolppanen, AM; Koponen, M; Tanskanen, A; Tiihonen, J; Hartikainen, S; Taipale, H. 2020. Journal of Alzheimer's disease. 73: 1243-1251 -
Causes of death in a nationwide cohort of community-dwellers with Alzheimer's disease
Tolppanen, Anna-Maija; Taipale, Heidi; Koponen, Marjaana; Tiihonen, Jari; Hartikainen, Sirpa. 2020. Bmc geriatrics. 20: 441 -
Complications of Pelvic Organ Prolapse Surgery in the 2015 Finnish Pelvic Organ Prolapse Surgery Survey Study
Wihersaari, Olga; Karjalainen, Päivi; Tolppanen, Anna-Maija; Mattsson, Nina; Jalkanen, Jyrki; Nieminen, Kari. 2020. Obstetrics and gynecology. 136: 1135-1144 -
Detection of medications associated with Alzheimer's disease using ensemble methods and cooperative game theory
Braithwaite, B; Paananen, J; Taipale, H; Tanskanen, A; Tiihonen, J; Hartikainen, S; Tolppanen, A-M. 2020. International journal of medical informatics. 141: 104142 -
Incidence of muscle relaxant use in relation to diagnosis of Parkinson's disease
Paakinaho, Anne; Karttunen, Niina; Koponen, Marjaana; Taipale, Heidi; Tolppanen, Anna-Maija; Hartikainen, Sirpa; Tiihonen, Miia. 2020. International journal of clinical pharmacy. 42: 336-340 -
Late-life personality traits, cognitive impairment, and mortality in a population-based cohort
Neuvonen, Elisa; Hall, Anette; Tolppanen, Anna-Maija; Ngandu, Tiia; Rusanen, Minna; Laatikainen, Tiina; Soininen, Hilkka; Kivipelto, Miia; Solomon, Alina. 2020. International journal of geriatric psychiatry. 35: 989-999 -
Length of hospital stay after hip fracture and readmission rates of persons with and without Alzheimer's disease: a matched cohort study
Rajamaki, Blair; Koponen, Marjaana; Hartikainen, Sirpa; Tolppanen, Anna-Maija. 2020. Bmc geriatrics. 20: 214 -
Length of hospital stay for hip fracture and 30-day mortality in people with Alzheimer's disease: a cohort study in Finland
Lavikainen, Piia; Koponen, Marjaana; Taipale, Heidi; Tanskanen, Antti; Tiihonen, Jari; Hartikainen, Sirpa; Tolppanen, Anna-Maija. 2020. Journals of gerontology series a: biological sciences and medical sciences. 75: 2184-2192 -
Metformin and risk of Alzheimer's disease among community-dwelling people with diabetes: a national case-control study
Sluggett, JK; Koponen, M; Bell, JS; Taipale, H; Tanskanen, A; Tiihonen, J; Uusitupa, M; Tolppanen, AM; Hartikainen, S. 2020. Journal of clinical endocrinology and metabolism. 105: dgz234 -
Minimal important difference and patient acceptable symptom state for PFDI-20 and POPDI-6 in POP surgery
Karjalainen, Päivi K; Mattsson, Nina K; Jalkanen, Jyrki T; Nieminen, Kari; Tolppanen, Anna-Maija. 2020. International urogynecology journal. 2021; 32: 3169-3176 -
Parkinsonin taudin lääkkeiden erityiskorvausoikeuden saajien määrän muutos vuosina 1996-2015
Anttila, Margareta; Hartikainen, Sirpa; Herukka, Sanna-Kaisa; Kaasinen, Valtteri; Tolppanen, Anna-Maija. 2020. Lääkärilehti. 75: 2297-2303 -
Pelvic organ prolapse surgery and quality of life - a nationwide cohort study
Mattsson, NK; Karjalainen, P; Tolppanen, AM; Heikkinen, AM; Sintonen, H; Härkki, P; Nieminen, K; Jalkanen, J. 2020. American journal of obstetrics and gynecology. 222: 588.e1-588.e10 -
Prevalence of cardiovascular drug use before and after diagnosis of Alzheimer's disease
Vu, Mai; Koponen, Marjaana; Taipale, Heidi; Tanskanen, Antti; Tiihonen, Jari; Kettunen, Raimo; Hartikainen, Sirpa; Tolppanen, Anna-Maija. 2020. International journal of cardiology. 300: 221-225 -
Psychotropic Drug-Associated Pneumonia in Older Adults
Rajamäki, Blair; Hartikainen, Sirpa; Tolppanen, Anna-Maija. 2020. Drugs and aging. 37: 241-261 -
Psykoosilääkkeiden käyttö on pitkäkestoista Alzheimerin tautia sairastavilla
Liehu, Maija; Tiihonen, Miia; Taipale, Heidi; Tanskanen, Antti; Tiihonen, Jari; Tolppanen, Anna-Maija; Hartikainen, Sirpa; Koponen, Marjaana. 2020. Dosis. 36: 6-23 -
The Risk of Head Injuries Associated With Antipsychotic Use Among Persons With Alzheimer's disease
Tapiainen, V; Lavikainen, P; Koponen, M; Taipale, H; Tanskanen, A; Tiihonen, J; Hartikainen, S; Tolppanen, AM. 2020. Journal of the american geriatrics society. 68: 595-602 -
Tiatsididiureettien käyttö suurentaa luuntiheyttä ja pienentää murtumariskiä - järjestelmällinen kirjallisuuskatsaus ja meta-analyysi
Rysä, Jaana; Lehtonen, Elise; Tolppanen, Anna-Maija; Hukkanen, Janne. 2020. Dosis. 36: 180-195 -
Accumulation of Hospital Days Among Antipsychotic Initiators With Alzheimer's Disease
Koponen, Marjaana; Lavikainen, Piia; Taipale, Heidi; Tanskanen, Antti; Tiihonen, Jari; Hartikainen, Sirpa; Tolppanen, Anna-Maija. 2019. Journal of the american medical directors association. 20: 1488-1494.e3 -
Alzheimer-potilaat ja psyykenlääkkeiden käyttö 2005-2011
Juhola, Laura; Taipale, Heidi; Koponen, Marjaana; Tanskanen, Antti; Tiihonen, Jari; Hartikainen, Sirpa; Tolppanen, Anna-Maija. 2019. Lääkärilehti. 74: 609-616 -
Antiepileptic Drug Use Is Associated with an Increased Risk of Pneumonia Among Community-Dwelling Persons with Alzheimer's Disease-Matched Cohort Study
Taipale, H; Lampela, P; Koponen, M; Tanskanen, A; Tiihonen, J; Hartikainen, S; Tolppanen, AM. 2019. Journal of Alzheimer's disease. 68: 127-136 -
Antiepileptic Drugs and Accumulation of Hospital Days Among Persons With Alzheimer's Disease
Lavikainen, Piia; Taipale, Heidi; Tanskanen, Antti; Koponen, Marjaana; Tiihonen, Jari; Hartikainen, Sirpa; Tolppanen, Anna-Maija. 2019. Journal of the american medical directors association. 20: 751-758 -
Cell therapy for ischemic stroke: are differences in preclinical and clinical study design responsible for the translational loss of efficacy?
Cui, LL; Golubczyk, D; Tolppanen, AM; Boltze, J; Jolkkonen, J. 2019. Annals of neurology. 86: 5-16 -
Hospital-Treated Pneumonia Associated with Opioid Use Among Community Dwellers with Alzheimer's Disease
Hamina, A; Taipale, H; Karttunen, N; Tanskanen, A; Tiihonen, J; Tolppanen, AM; Hartikainen, S. 2019. Journal of Alzheimer's disease. 69: 807-816 -
Incidence of head injury and traumatic brain injury among people with Alzheimer's disease
Ilmaniemi, S; Taipale, H; Tanskanen, A; Tiihonen, J; Hartikainen, S; Tolppanen, AM. 2019. Journal of epidemiology and community health. 73: 451-454 -
Incidence of prescription vitamin B12 use in relation to diagnosis of Alzheimer's disease among community-dwelling persons
Pölönen, Satu; Tiihonen, Miia; Nykänen, Irma; Taipale, Heidi; Tolppanen, Anna-Maija; Hartikainen, Sirpa. 2019. Journal of public health. 27: 775-779 -
Long-term thiazide use and risk of low-energy fractures among persons with Alzheimer's disease-nested case-control study
Taipale, H; Rysä, J; Hukkanen, J; Koponen, M; Tanskanen, A; Tiihonen, J; Kröger, H; Hartikainen, S; Tolppanen, AM. 2019. Osteoporosis international. 30: 1481-1489 -
Methodological Challenges in Epidemiological Studies
Ilomäki, Jenni; Tolppanen, Anna-Maija. Teoksessa: Babar, Zaaher-Ud-Din(toim.) , 2019. Encyclopedia of Pharmacy Practice and Clinical Pharmacy. Volume 2. s. 382-390. Academic press -
Methods of surgery for pelvic organ prolapse in a nationwide Cohort (FINPOP 2015)
Mattsson, NK; Karjalainen, P; Tolppanen, AM; Heikkinen, AM; Jalkanen, J; Härkki, P; Nieminen K. 2019. Acta obstetricia et gynecologica scandinavica. 98: 451-459 -
Opioid Use After Hospital Care due to Hip Fracture Among Community-Dwelling Persons With and Without Alzheimer's Disease
Lintula, E; Tiihonen, M; Taipale, H; Tolppanen, AM; Tanskanen, A; Tiihonen, J; Hartikainen, S; Hamina, A. 2019. Drugs and aging. 2020; 37: 193-203 -
Predictors of high hospital care and medication costs and cost trajectories in community-dwellers with Alzheimer's disease
Kalamägi, J; Lavikainen, P; Taipale, H; Tanskanen, A; Tiihonen, J; Hartikainen, S; Tolppanen, AM. 2019. Annals of medicine. 51: 294-305 -
Purchases of medical therapy recommended for coronary artery disease before and after elective revascularisation
Heiskanen, J; Hartikainen, J; Martikainen, J; Miettinen, H; Hippeläinen, M; Roine, RP; Tolppanen, AM. 2019. European journal of clinical pharmacology. 2020; 76: 81-88 -
The relationship of defecation symptoms and posterior vaginal wall prolapse in women undergoing pelvic organ prolapse surgery
Karjalainen, PK; Mattsson, NK; Nieminen, K; Tolppanen, AM; Jalkanen, JT. 2019. American journal of obstetrics and gynecology. 221: 480.e1-480.e10 -
Antiepileptic Drug Use and the Risk of Stroke Among Community-Dwelling People With Alzheimer Disease: A Matched Cohort Study
Sarycheva, Tatyana; Lavikainen, Piia; Taipale, Heidi; Tiihonen, Jari; Tanskanen; Antti; Hartikainen, Sirpa; Tolppanen, Anna-Maija. 2018. Journal of the american heart association. Cardiovascular and cerebrovascular disease. 7: e009742 -
Antipsychotic Use and the Risk of Initiating Medication for Benign Prostate Hyperplasia in Persons With Alzheimer Disease: A Matched Cohort Study
Orsel, Kim; Taipale, Heidi; Raatikainen, Sami; Lampela, Pasi; Tolppanen, Anna-Maija; Koponen, Marjaana; Tanskanen, Antti; Tiihonen, Jari; Gardarsdottir, Helga; Hartikainen, Sirpa. 2018. Journal of clinical psychopharmacology. 38: 494-497 -
Concomitant use of benzodiazepines and opioids in community-dwelling older people with or without Alzheimer's disease - A nationwide register-based study in Finland
Karttunen, Niina; Taipale, Heidi; Hamina, Aleksi; Tanskanen, Antti; Tiihonen, Jari; Tolppanen, Anna-Maija; Hartikainen, Sirpa. 2018. International journal of geriatric psychiatry. 2019; 34: 280-288 -
Duration of new antidepressant use and factors associated with discontinuation among community-dwelling persons with Alzheimer's disease
Kettunen, Reetta; Taipale, Heidi; Tolppanen, Anna-Maija; Tanskanen, Antti; Tiihonen, Jari; Hartikainen, Sirpa; Koponen, Marjaana. 2018. European journal of clinical pharmacology. 2019; 75: 417-425 -
Editorial: let's take a break from studying the PPI-fracture association - Authors' reply
Torvinen-Kiiskinen, S; Tolppanen, AM; Koponen, M; Tanskanen, A; Tiihonen, J; Hartikainen, S; Taipale, H. 2018. Alimentary pharmacology and therapeutics. 47: 1544-1545 -
Hospitalization after Oral Antibiotic Initiation in Finnish Community Dwellers with and without Alzheimer's Disease: Retrospective Register-Based Cohort Study
Järvinen, Heli; Taipale, Heidi; Koponen, Marjaana; Tanskanen, Antti; Tiihonen, Jari; Tolppanen, Anna-Maija; Hartikainen, Sirpa. 2018. Journal of Alzheimer's disease. 64: 437-445 -
Impact of opioid initiation on antipsychotic and benzodiazepine and related drug use among persons with Alzheimer's disease
Hamina, Aleksi; Lavikainen, Piia; Tanskanen, Antti; Tolppanen, Anna-Maija; Tiihonen, Jari; Hartikainen, Sirpa; Taipale, Heidi. 2018. International psychogeriatrics. 30: 947-956 -
Incidence and Prevalence of Antiepileptic Medication Use in Community-Dwelling Persons with and without Alzheimer's Disease
Sarycheva, Tatyana; Taipale, Heidi; Lavikainen, Piia; Tiihonen, Jari; Tanskanen, Antti; Hartikainen, Sirpa; Tolppanen, Anna-Maija. 2018. Journal of Alzheimer's disease. 66: 387-395 -
Incident opioid use and risk of hip fracture among persons with Alzheimer's disease, a nationwide matched cohort study
Taipale, Heidi; Hamina, Aleksi; Karttunen, Niina; Koponen, Marjaana; Tanskanen, Antti; Tiihonen, Jari; Hartikainen, Sirpa; Tolppanen, Anna-Maija. 2018. Pain. 2019; 160: 417-423 -
Kansalliset rekisteritiedot lääke-epidemiologisen tutkimuksen perustana
Sund, Reijo; Tolppanen, Anna-Maija. 2018. Sic!. 8: 25-26 -
Proton pump inhibitor use and risk of hip fractures among community-dwelling persons with Alzheimer's disease - a nested case-control study
Torvinen-Kiiskinen, S; Tolppanen, AM; Koponen, M; Tanskanen, A; Tiihonen, J; Hartikainen, S; Taipale, H. 2018. Alimentary pharmacology and therapeutics. 47: 1135-1142 -
Psychotropic drugs use and psychotropic polypharmacy among persons with Alzheimer's disease
Orsel, Kim; Taipale, Heidi; Tolppanen, Anna-Maija; Koponen, Marjaana; Tanskanen, Antti; Tiihonen, Jari; Gardarsdottir, Helga; Hartikainen, Sirpa. 2018. European neuropsychopharmacology. 28: 1260-1269 -
Reply to: Use of Antiepileptic Drugs and Dementia Risk - an Analysis of Finnish Health Register and German Health Insurance Data
Taipale, Heidi; Gomm, Willy; Broich, Karl; Maier, Wolfgang; Tolppanen, Anna-Maija; Hartikainen, Sirpa; Haenisch, Britta. 2018. Journal of the american geriatrics society. 66: 1853-1854 -
Systemic Estrogen Use and Discontinuation After Alzheimer's Disease Diagnosis in Finland 2005-2012: A Nationwide Exposure-Matched Cohort Study
Tolppanen, Anna-Maija; Tiihonen, Miia; Taipale, Heidi; Koponen, Marjaana; Tanskanen, Antti; Lavikainen, Piia; Tiihonen, Jari; Hartikainen, Sirpa. 2018. Drugs and aging. 35: 985-992 -
The risk of Alzheimer's disease associated with benzodiazepines and related drugs: a nested case-control study
Tapiainen, V; Taipale, H; Tanskanen, A; Tiihonen, J; Hartikainen, S; Tolppanen, A-M. 2018. Acta psychiatrica scandinavica. 138: 91-100 -
Use of antiepileptic drugs and dementia risk - an analysis of Finnish health register and German health insurance data
Taipale, H; Gomm, W; Broich, K; Maier, W; Tolppanen, AM; Tanskanen, A; Tiihonen, J; Hartikainen, S; Haenisch, B. 2018. Journal of the american geriatrics society. 66: 1123-1129 -
Antidepressant use and risk of hip fractures among community-dwelling persons with and without Alzheimer's disease
Torvinen-Kiiskinen Sanna, Tolppanen Anna-Maija, Koponen Marjaana, Tanskanen Antti, Tiihonen Jari, Hartikainen Sirpa, Taipale Heidi. 2017. International journal of geriatric psychiatry. 32: e107-e115 -
Antipsychotic use and the risk of hip fracture among community-dwelling persons with Alzheimer's disease
Koponen M, Taipale H, Lavikainen P, Tanskanen A, Tiihonen J, Tolppanen AM, Ahonen R, Hartikainen S. 2017. Journal of clinical psychiatry. 78: e257-e263 -
Does routinely collected patient-reported outcome data represent the actual case-mix of elective coronary revascularization patients?
Oinasmaa S, Heiskanen J, Hartikainen J, Hippeläinen M, Miettinen H, Martikainen J, Roine RP, Tolppanen AM. 2017. European heart journal : quality of care and clinical outcomes. 2018; 4: 113-119 -
Drug exposure in register-based research - An expert-opinion based evaluation of methods
Tanskanen A, Taipale H, Koponen M, Tolppanen AM, Hartikainen S, Ahonen R, Tiihonen J. 2017. PLoS ONE. 12: e0184070 -
Head or brain injuries and Alzheimer's disease : a nested case-control register study
Tolppanen Anna-Maija, Taipale Heidi, Hartikainen Sirpa. 2017. Alzheimer's & dementia. 13: 1371-1379 -
Hospital-treated mental and behavioral disorders and risk of Alzheimer's disease: A nationwide nested case-control study
Tapiainen V, Hartikainen S, Taipale H, Tiihonen J, Tolppanen A-M. 2017. European psychiatry. 43: 92-98 -
Incident Use of a Potentially Inappropriate Medication and Hip Fracture in Community-Dwelling Older Persons With Alzheimer's Disease
Hyttinen V, Taipale H, Tolppanen A-M, Tanskanen A, Tiihonen J, Hartikainen S, Valtonen H. 2017. Annals of pharmacotherapy. 51: 725-734 -
Is Alzheimer's Disease Associated with Previous Opioid Use?
Taipale H, Hamina A, Lampela P, Tanskanen A, Tiihonen J, Karttunen N, Tolppanen AM, Hartikainen S. 2017. Pain medicine. 2018; 19: 2115-2121 -
Long-term use of proton pump inhibitors among community-dwelling persons with and without Alzheimer's disease
Juntunen Heidi, Taipale Heidi, Tanskanen Antti, Tolppanen Anna-Maija, Tiihonen Jari, Hartikainen Sirpa, Tiihonen Miia. 2017. European journal of clinical pharmacology. 73: 1149-1158 -
No Association Between Proton Pump Inhibitor Use and Risk of Alzheimer's Disease
Taipale Heidi, Tolppanen Anna-Maija, Tiihonen Miia, Tanskanen Antti, Tiihonen Jari, Hartikainen Sirpa. 2017. American journal of gastroenterology. 112: 1802-1808 -
Postmenopausal hormone therapy and Alzheimer disease. A prospective cohort study
Imtiaz B, Tuppurainen M, Rikkonen T, Kivipelto M, Soininen H, Kröger H, Tolppanen A-M. 2017. Neurology. 88: 1062-1068 -
Regional changes in psychotropic use among Finnish persons with newly diagnosed Alzheimer's disease in 2005-2011
Tolppanen A-M, Voutilainen A, Taipale H, Tanskanen A, Lavikainen P, Koponen M, Tiihonen J, Hartikainen S. 2017. PLoS ONE. 12: e0173450 -
Risk of Alzheimer's disease among users of postmenopausal hormonetherapy: A nationwide case-control study
Imtiaz B, Taipale H, Tanskanen A, Tiihonen M, Kivipelto M, Heikkinen A-M, Tiihonen J, Soininen H, Hartikainen S, Tolppanen A-M. 2017. Maturitas. 98: 7-13 -
Risk of death associated with new benzodiazepine use among persons with Alzheimer disease: A matched cohort study
Saarelainen Laura, Tolppanen Anna-Maija, Koponen Marjaana, Tanskanen Antti, Tiihonen Jari, Hartikainen Sirpa, Taipale Heidi. 2017. International journal of geriatric psychiatry. 2018; 33: 583-590 -
Risk of head and traumatic brain injuries associated with antidepressant use among community-dwelling persons with Alzheimer's disease: a nationwide matched cohort study
Taipale Heidi, Koponen Marjaana, Tanskanen Antti, Lavikainen Piia, Sund Reijo, Tiihonen Jari, Hartikainen Sirpa, Tolppanen Anna-Maija. 2017. Alzheimer's research and therapy. 9: 59 -
Risk of pneumonia associated with incident benzodiazepine use among community-dwelling persons with Alzheimer's disease
Taipale Heidi, Tolppanen Anna-Maija, Koponen Marjaana, Tanskanen Antti, Lavikainen Piia, Sund Reijo, Tiihonen Jari, Hartikainen Sirpa. 2017. Canadian medical association journal. 189: E519-E529 -
Screening approach for identifying candidate drugs and drug-drug interactions related to hip fracture risk in persons with Alzheimer disease
Tolppanen A-M, Taipale H, Koponen M, Tanskanen A, Lavikainen P, Paananen J, Tiihonen J, Hartikainen S. 2017. Pharmacoepidemiology and drug safety. 26: 875-889 -
Targeted identification of adverse events in coronary artery disease patients based on patient-reported outcomes
Heiskanen J, Tolppanen A-M, Martikainen J, Hartikainen J, Miettinen H, Hippeläinen M, Roine RP. 2017. Journal of comparative effectiveness research. 6: 583-589 -
Use of benzodiazepines and related drugs is associated with risk of stroke among persons with Alzheimer's disease
Taipale Heidi, Koponen Marjaana, Tanskanen Antti, Lavikainen Piia, Tolppanen Anna-Maija, Sund Reijo, Tiihonen Jari, Hartikainen Sirpa. 2017. International clinical psychopharmacology. 32: 135-141 -
Validation of the short forms of the Pelvic Floor Distress Inventory (PFDI-20), Pelvic Floor Impact Questionnaire (PFIQ-7), and Pelvic Organ Prolapse/Urinary Incontinence Sexual Questionnaire (PISQ-12) in Finnish
Mattsson NK, Nieminen K, Heikkinen A-M, Jalkanen J, Koivurova S, Eloranta M-L, Suvitie P, Tolppanen A-M. 2017. Health and quality of life outcomes. 15: 88 -
A Comparison of Sex Differences in Psychotropic Medication Use in Older People with Alzheimer's Disease in the US and Finland
Moga Daniela C, Taipale Heidi, Tolppanen Anna-Maija, Tanskanen Antti, Tiihonen Jari, Hartikainen Sirpa, Wu Qishan, Jicha Gregory A, Gnjidic Danijela. 2016. Drugs and aging. 2017; 34: 55-65 -
Agreement between PRE2DUP register data modeling method and comprehensive drug use interview among older persons
Taipale Heidi, Tanskanen Antti, Koponen Marjaana, Tolppanen Anna-Maija, Tiihonen Jari, Hartikainen Sirpa. 2016. Clinical epidemiology. 8: 363-371 -
Alueelliset erot sairaalapäivissä ja lääkekustannuksissa Alzheimerin tautia sairastavilla ja verrokeilla [English Summary: Regional differences in number of hospital days and drug costs in people with and without Alzheimer's disease]
Taipale Heidi, Tolppanen Anna-Maija, Purhonen Maija, Tanskanen Antti, Ahonen Riitta, Tiihonen Jari, Hartikainen Sirpa. 2016. Lääkärilehti. 71: 1613-1619a -
Anticholinergic Exposure and Risk of Pneumonia in Persons with Alzheimer's Disease: A Nested Case-Control Study
Lampela Pasi, Tolppanen Anna-Maija, Tanskanen Antti, Tiihonen Jari, Hartikainen Sirpa, Taipale Heidi. 2016. Journal of Alzheimer's disease. 2017; 56: 119-128 -
Antipsychotic use and risk of hospitalization or death due to pneumonia in persons with and without Alzheimer's disease
Tolppanen Anna-Maija, Koponen Marjaana, Tanskanen Antti, Lavikainen Piia, Sund Reijo, Tiihonen Jari, Hartikainen Sirpa, Taipale Heidi. 2016. Chest. 150: 1233-1241 -
Cohort profile: the Finnish Medication and Alzheimer's disease (MEDALZ) study
Tolppanen Anna-Maija, Taipale Heidi, Koponen Marjaana, Lavikainen Piia, Tanskanen Antti, Tiihonen Jari, Hartikainen Sirpa. 2016. BMJ open. 6: e012100 -
Comparison of EQ-5D and 15D instruments for assessing the health-related quality of life in cardiac surgery patients
Heiskanen Jari, Tolppanen Anna-Maija, Roine Risto P, Hartikainen Juha, Hippeläinen Mikko, Miettinen Heikki, Martikainen Janne. 2016. European heart journal : quality of care and clinical outcomes. 2: 193-200 -
Comparison of predictors of hip fracture and mortality after hip fracture in community-dwellers with and without Alzheimer's disease - exposure-matched cohort study
Tolppanen Anna-Maija, Taipale Heidi, Tanskanen Antti, Tiihonen Jari, Hartikainen Sirpa. 2016. Bmc geriatrics. 16: 204 -
Dementialääkkeitä käytetään esitettyä pidempään [Ajassa
Hartikainen Sirpa, Paananen Jussi, Taipale Heidi, Tanskanen Antti, Tiihonen Jari, Tolppanen Anna-Maija. 2016. Lääkärilehti. 71: 3003 -
Differences in analgesic use in community-dwelling persons with and without Alzheimer's disease
Hamina Aleksi, Taipale Heidi, Tanskanen Antti, Tolppanen Anna-Maija, Tiihonen Jari, Hartikainen Sirpa. 2016. European journal of pain. 2017; 21: 658-667 -
Drug use in persons with and without Alzheimer's disease aged 90 years or more
Taipale Heidi, Koponen Marjaana, Tanskanen Antti, Tolppanen Anna-Maija, Tiihonen Jari, Hartikainen Sirpa. 2016. Age and ageing. 45: 900-904 -
Estradiol and Cognition in the Cardiovascular Risk Factors, Aging and Dementia (CAIDE) Cohort Study
Imtiaz Bushra, Tolppanen Anna-Maija, Solomon Alina, Soininen Hilkka, Kivipelto Miia. 2016. Journal of Alzheimer's disease. 2017; 56: 453-458 -
Incidence of Bisphosphonate Use in Relation to Diagnosis of Alzheimer's Disease in Community-Dwelling Persons
Tiihonen Miia, Taipale Heidi, Tolppanen Anna-Maija, Hartikainen Sirpa. 2016. Journal of the american geriatrics society. 64: e48 - e49 -
Incidence of antidepressant use in community-dwelling persons with and without Alzheimer's disease: 13-year follow-up
Puranen Arto, Taipale Heidi, Koponen Marjaana, Tanskanen Antti, Tolppanen Anna-Maija, Tiihonen Jari, Hartikainen Sirpa. 2016. International journal of geriatric psychiatry. 2017; 32: 94-101 -
Long-term use of opioids for non-malignant pain among community-dwelling persons with and without Alzheimer disease in Finland: a nationwide register-based study
Hamina Aleksi, Taipale Heidi, Tanskanen Antti, Tolppanen Anna-Maija, Karttunen Niina, Pylkkänen Liisa, Tiihonen Jari, Hartikainen Sirpa. 2016. Pain. 2017; 158: 252-260 -
Month and Season of Birth as a Risk Factor for Alzheimer's Disease: A Nationwide Nested Case-control Study
Tolppanen Anna-Maija, Ahonen Riitta, Koponen Marjaana, Lavikainen Piia, Purhonen Maija, Taipale Heidi, Tanskanen Antti, Tiihonen Jari, Tiihonen Miia, Hartikainen Sirpa. 2016. Journal of preventive medicine and public health. 49: 134-138 -
Muistisairauksista aiheutuva erikoissairaanhoito ennen Alzheimerin taudin lääkekorvausoikeutta [English summary: Periods of hospital treatment and hospital visits before entitlement to special reimbursement for antidemetia medication]
Heiskanen Jari, Hartikainen Sirpa, Taipale Heidi, Tolppanen Anna-Maija. 2016. Lääkärilehti. 71: 1607-1611a -
Psykoosilääkkeet yhteydessä Alzheimer-potilaiden keuhkokuumeriskiin
Tolppanen Anna-Maija, Koponen Marjaana, Tanskanen Antti, Lavikainen Piia, Sund Reijo, Tiihonen Jari, Hartikainen Sirpa, Taipale Heidi. 2016. Duodecim. 132: 1490 -
Risk Factors for Initiation of Potentially Inappropriate Medications in Community-Dwelling Older Adults with and without Alzheimer's Disease
Hyttinen Virva, Taipale Heidi, Tanskanen Antti, Tiihonen Jari, Tolppanen Anna-Maija, Hartikainen Sirpa, Valtonen Hannu. 2016. Drugs and aging. 2017; 34: 67-77 -
Risk of Hip Fracture in Benzodiazepine Users With and Without Alzheimer Disease
Saarelainen Laura, Tolppanen Anna-Maija, Koponen Marjaana, Tanskanen Antti, Sund Reijo, Tiihonen Jari, Hartikainen Sirpa, Taipale Heidi. 2016. Journal of the american medical directors association. 2017; 18: 87.e15-87.e21 -
Risk of Mortality associated with Antipsychotic Monotherapy and Polypharmacy among Community-Dwelling Persons with Alzheimer's Disease
Koponen Marjaana, Taipale Heidi, Lavikainen Piia, Tanskanen Antti, Tiihonen Jari, Tolppanen Anna-Maija, Ahonen Riitta, Hartikainen Sirpa. 2016. Journal of Alzheimer's disease. 2017; 56: 107-118 -
The coverage of elective revascularisation procedure codes in the National Finnish Hospital Discharge Register
Heiskanen Jari, Martikainen Janne, Miettinen Heikki, Hippeläinen Mikko, Roine Risto P, Hartikainen Juha, Tolppanen Anna-Maija. 2016. Annals of medicine. 48: 552-558 -
Use of antidementia drugs and risk of pneumonia in older persons with Alzheimer's disease
Lampela Pasi, Tolppanen Anna-Maija, Tanskanen Antti, Tiihonen Jari, Lavikainen Piia, Hartikainen Sirpa, Taipale Heidi. 2016. Annals of medicine. 2017; 49: 230-239 -
30-Day Mortality after Cardiovascular Events in Persons with or without Alzheimer's Disease
Heiskanen Jari, Hartikainen Sirpa, Roine Risto P, Tolppanen Anna-Maija. 2015. Journal of Alzheimer's disease. 48: 241-249 -
Associations across spatial patterns of disease incidences, socio-demographics, and land use in Finland 1991-2010
Voutilainen Ari, Hartikainen Sirpa, Sherwood Paula R, Taipale Heidi, Tolppanen Anna-Maija, Vehviläinen-Julkunen Katri. 2015. Scandinavian journal of public health. 43: 356-363 -
From prescription drug purchases to drug use periods - a second generation method (PRE2DUP)
Tanskanen Antti, Taipale Heidi, Koponen Marjaana, Tolppanen Anna-Maija, Hartikainen Sirpa, Ahonen Riitta, Tiihonen Jari. 2015. Bmc medical informatics and decision making. 15: 21 -
Health condition and physical function as predictors of adherence in long-term strength and balance training among community-dwelling older adults
Aartolahti Eeva, Tolppanen Anna-Maija, Lönnroos Eija, Hartikainen Sirpa, Häkkinen Arja. 2015. Archives of gerontology and geriatrics. 61: 452-457 -
Hospital care and drug costs from five years before until two years after the diagnosis of Alzheimer's disease in a Finnish nationwide cohort
Taipale Heidi, Purhonen Maija, Tolppanen Anna-Maija, Tanskanen Antti, Tiihonen Jari, Hartikainen Sirpa. 2015. Scandinavian journal of public health. 44(2016): 150-158 -
Incidence of antipsychotic use in relation to diagnosis of Alzheimer's disease among community-dwelling persons
Koponen Marjaana, Tolppanen Anna-Maija, Taipale Heidi, Tanskanen Antti, Tiihonen Jari, Johnell Kristina, Fastbom Johan, Ahonen Riitta, Hartikainen Sirpa. 2015. British journal of psychiatry. 207: 444-449 -
Long-term use of antipsychotics among community-dwelling persons with Alzheimer's disease: A nationwide register-based study
Koponen Marjaana, Taipale Heidi, Tanskanen Antti, Tolppanen Anna-Maija, Tiihonen Jari, Ahonen Riitta, Hartikainen Sirpa. 2015. European neuropsychopharmacology. 25: 1706-1713 -
Long-term use of benzodiazepines and related drugs among community-dwelling individuals with and without Alzheimer's disease
Taipale Heidi, Koponen Marjaana, Tanskanen Antti, Tolppanen Anna-Maija, Tiihonen Jari, Hartikainen Sirpa. 2015. International clinical psychopharmacology. 30: 202-208 -
The Incidence of Benzodiazepine and Related Drug Use in Persons with and without Alzheimer's Disease
Saarelainen Laura, Taipale Heidi, Koponen Marjaana, Tanskanen Antti, Tolppanen Anna-Maija, Tiihonen Jari, Hartikainen Sirpa. 2015. Journal of Alzheimer's disease. 2016; 49: 809-818 -
Antidementia drug use among community-dwelling individuals with Alzheimer's disease in Finland: a nationwide register-based study
Taipale Heidi, Tanskanen Antti, Koponen Marjaana, Tolppanen Anna-Maija, Tiihonen Jari, Hartikainen Sirpa. 2014. International clinical psychopharmacology. 29: 216-223 -
Antipsychotic Doses Among Community-Dwelling Persons With Alzheimer Disease in Finland
Taipale Heidi, Koponen Marjaana, Tanskanen Antti, Tolppanen Anna-Maija, Tiihonen Jari, Hartikainen Sirpa. 2014. Journal of clinical psychopharmacology. 34: 435-440 -
Antipsychotic Polypharmacy among a Nationwide Sample of Community-Dwelling Persons with Alzheimer's Disease
Taipale Heidi, Koponen Marjaana, Tanskanen Antti, Tolppanen Anna-Maija, Tiihonen Jari, Hartikainen Sirpa. 2014. Journal of Alzheimer's disease. 41: 1223-1228 -
From prescriptions to drug use periods - things to notice
Tanskanen Antti, Taipale Heidi, Koponen Marjaana, Tolppanen Anna-Maija, Hartikainen Sirpa, Ahonen Riitta, Tiihonen Jari. 2014. Bmc research notes. 7: 796 -
From spatial ecology to spatial epidemiology: modeling spatial distributions of different cancer types with principal coordinates of neighbor matrices
Voutilainen Ari, Tolppanen Anna-Maija, Vehviläinen-Julkunen Katri, Sherwood Paula R.. 2014. Emerging themes in epidemiology. 11: 11 -
Future directions in Alzheimer's disease from risk factors to prevention
Imtiaz Bushra, Tolppanen Anna-Maija, Kivipelto Miia, Soininen Hilkka. 2014. Biochemical pharmacology. 88: 661-670 -
High prevalence of psychotropic drug use among persons with and without Alzheimer's disease in Finnish nationwide cohort
Taipale Heidi, Koponen Marjaana, Tanskanen Antti, Tolppanen Anna-Maija, Tiihonen Jari, Hartikainen Sirpa. 2014. European neuropsychopharmacology. 24: 1729-1737 -
Hospital admissions, outpatient visits and healthcare costs of community-dwellers with Alzheimer's disease
Tolppanen Anna-Maija, Taipale Heidi, Purmonen Timo, Koponen Marjaana, Soininen Hilkka, Hartikainen Sirpa. 2014. Alzheimer's & dementia. 2015; 11: 955-963 -
Impact of high risk drug use on hospitalization and mortality in older people with and without Alzheimer's disease: a national population cohort study
Gnjidic Danijela, Hilmer Sarah N, Hartikainen Sirpa, Tolppanen Anna-Maija, Taipale Heidi, Koponen Marjaana, Bell J. Simon. 2014. PLoS ONE. 9: e83224 -
Late-life cynical distrust, risk of incident dementia, and mortality in a population-based cohort
Neuvonen Elisa, Rusanen Minna, Solomon Alina, Ngandu Tiia, Laatikainen Tiina, Soininen Hilkka, Kivipelto Miia, Tolppanen Anna-Maija. 2014. Neurology. 82: 2205-2212 -
Leisure-time physical activity from mid- to late life, body mass index, and risk of dementia
Tolppanen Anna-Maija, Solomon Alina, Kulmala Jenni, Kåreholt Ingemar, Ngandu Tiia, Rusanen Minna, Laatikainen Tiina, Soininen Hilkka, Kivipelto Miia. 2014. Alzheimer's & dementia. Epub ahead of print: - -
MEDALZ -Medication use and Alzheimer's disease
Hartikainen Sirpa, Tolppanen Anna-Maija, Taipale Heidi, Koponen Marjaana. 2014. Dosis. 30: 234 -
Oophorectomy, Hysterectomy, and Risk of Alzheimer's Disease: A Nationwide Case-Control Study
Imtiaz Bushra, Tuppurainen Marjo, Tiihonen Miia, Kivipelto Miia, Soininen Hilkka, Hartikainen Sirpa, Tolppanen Anna-Maija. 2014. Journal of Alzheimer's disease. 42: 575-581 -
History of medically treated diabetes and risk of Alzheimer disease in a nationwide case-control study
Tolppanen Anna-Maija, Lavikainen Piia, Solomon Alina, Kivipelto Miia, Uusitupa Matti, Soininen Hilkka, Hartikainen Sirpa. 2013. Diabetes care. 36: 2015-2019 -
Incidence of stroke in people with Alzheimer disease. A national register-based approach
Tolppanen Anna-Maija, Lavikainen Piia, Solomon Alina, Kivipelto Miia, Soininen Hilkka, Hartikainen Sirpa. 2013. Neurology. 80: 353-358 -
Incident Hip Fractures among Community Dwelling Persons with Alzheimer's Disease in a Finnish Nationwide Register-Based Cohort
Tolppanen A-M, Lavikainen P, Soininen H, Hartikainen S. 2013. PLoS ONE. 8: e59124 -
Incident ischaemic heart disease in persons with Alzheimer's disease in a Finnish nationwide exposure-matched cohort
Tolppanen Anna-Maija, Kettunen Raimo, Ahonen Riitta, Soininen Hilkka, Hartikainen Sirpa. 2013. International journal of cardiology. 170: 195-201 -
Midlife and late-life body mass index and late-life dementia: results from a prospective population-based cohort
Tolppanen A-M, Ngandu T, Kåreholt I, Laatikainen T, Rusanen M, Soininen H, Kivipelto M. 2013. Journal of Alzheimer's disease. online: - -
Prediction of dementia in people with diabetes
Tolppanen Anna-Maija. 2013. The Lancet Diabetes & Endocrinology. 1: 164-165 -
Prospective association of 25-hydroxyvitamin d3 and d2 with childhood lung function, asthma, wheezing, and flexural dermatitis
Tolppanen AM, Sayers A, Granell R, Fraser WD, Henderson J, Lawlor DA. 2013. Epidemiology. 24: 310-319 -
Use of existing data sources in clinical epidemiology: Finnish health care registers in Alzheimer's disease research - the Medication use among persons with Alzheimer's disease (MEDALZ-2005) study
Tolppanen Anna-Maija, Taipale Heidi, Koponen Marjaana, Lavikainen Piia, Tanskanen Antti, Tiihonen Jari, Hartikainen Sirpa. 2013. Clinical epidemiology. 5: 277-285 -
Association of serum 25-hydroxyvitamin D3 and D2 with academic performance in childhood: findings from a prospective birth cohort.
Tolppanen Anna-Maija, Sayers Adrian, Fraser William D, Lawlor Debbie A.. 2012. Journal of epidemiology and community health. Epub ahead of print: Epub ahead of print -
Midlife Vascular Risk Factors and Alzheimer's Disease: Evidence from Epidemiological Studies
Tolppanen AM, Solomon A, Soininen H, Kivipelto M. 2012. Journal of Alzheimer's disease. 32: 531-40 -
Risk Factors for Variation in 25-Hydroxyvitamin D3 and D2 Concentrations and Vitamin D Deficiency in Children
Tolppanen Anna-Maija, Fraser Abigail, Fraser Wiliam D, Lawlor Debbie A. 2012. Journal of clinical endocrinology and metabolism. 97: 1202-1210 -
Serum 25-hydroxyvitamin d(3) and d(2) and non-clinical psychotic experiences in childhood
Tolppanen Anna-Maija, Sayers Adrian, Fraser William D, Lewis Glyn, Zammit Stanley, McGrath John, Lawlor Debbie A.. 2012. PLoS ONE. 7: e41575 -
The association of 25-hydroxyvitamin d(3) and d(2) with behavioural problems in childhood
Tolppanen Anna-Maija, Sayers A, Fraser Wiliam D, Lewis Glyn, Zammit Stan, Lawlor Debbie A. 2012. PLoS ONE. 7: e41575 -
The association of serum 25-hydroxyvitamin D3 and D2 with depressive symptoms in childhood - a prospective cohort study
Tolppanen Anna-Maija, Sayers Adrian, Fraser Wiliam D, Lewis Glyn, Zammit Stan, Lawlor Debbie A. 2012. Journal of child psychology and psychiatry. 53: 757-766 -
Serum 25-hydroxy-vitamin D and ionised calcium in relation to lung function and allergen skin tests
Tolppanen AM, Williams D, Henderson J, Lawlor DA. 2011. European journal of clinical nutrition. 65: 493-500 -
Tenomodulin variants, APOE and Alzheimer's disease in a Finnish case-control cohort. Negative results
Tolppanen AM, Helisalmi S, Hiltunen M, Kolehmainen M, Schwab U, Pirttilä T, Pulkkinen L, Uusitupa M & Soininen H.. 2011. Neurobiology of aging. 32: 546.e7-546.e9 -
The association of circulating 25-hydroxyvitamin D and calcium with cognitive performance in adolescents: cross-sectional study using data from the third National Health and Nutrition Examination Survey
Tolppanen AM, Williams D, Lawlor DA. 2011. Paediatric and perinatal epidemiology. 25: 67-74 -
The association of serum ionized calcium and vitamin D with adult cognitive performance
Tolppanen AM, Williams DM, Lawlor DA. 2011. Epidemiology. 22: 113-117 -
Association of the FTO gene variant (rs9939609) with cardiovascular disease in men with abnormal glucose metabolism - The Finnish Diabetes Prevention Study
Lappalainen T, Kolehmainen M, Schwab US, Tolppanen AM, Stančáková A, Lindström J, Eriksson JG, Keinänen-Kiukaanniemi S, Aunola S, Ilanne-Parikka P, Herder C, Koenig W, Gylling H, Kolb H &Tuomilehto J for the Finnish diabetes prevention study group. 2010. Nutrition metabolism and cardiovascular diseases. 2011/21: 691-698/2011 -
Tenomodulin gene and obesity-related phenolypes
Tolppanen A-M, Kolehmainen M, Pulkkinen L & Uusitupa M. 2010. Annals of medicine. 42: 265-275 -
Association of sequence variations in the gene encoding insulin-like growth factor binding protein 5 with adiponectin
Kallio P, Tolppanen A-M, Kolehmainen M, Poutanen K, Lindström J, Tuomilehto J, Kuulasmaa T, Kuusisto J, Pulkkinen L, Uusitupa M, Kallio P, Tolppanen A-M, Kolehmainen M, Poutanen K, Pulkkinen L, Uusitupa M. 2009. International journal of obesity. 33: 80-88 -
Genetic Association of the Tenomodulin Gene (TNMD) with Obesity- and Inflammation-Related Phenotypes
Tolppanen A-M. 2009. Kuopio University Publications D. Medical Sciences -
Single nucleotide polymorphisms of the tenomodulin gene (TNMD) in age-related macular degeneration
Tolppanen A-M, Nevalainen T, Kolehmainen M, Seitsonen S, Immonen I, Uusitupa M, Kaarniranta K, Pulkkinen L, Tolppanen A-M, Kolehmainen M, Uusitupa M, Pulkkinen L. 2009. Molecular vision. 15: 762-770 -
Variation in the UCP2 and UCP3 genes associated with abdominal obesity and serum lipids: The Finnish diabetes prevention study
Salopuro T, Pulkkinen L, Lindström J, Kolehmainen M, Tolppanen A-M, Eriksson JG, Valle TT, Aunola S, Ilanne-Parikka P, Keinänen-Kiukaanniemi S, Tuomilehto J, Laakso M, Uusitupa M, Salopuro T, Pulkkinen L, Kolehmainen M, Tolppanen A-M, Uusitupa M. 2009. Bmc medical genetics. 10: [13 p.] -
The genetic variation in the tenomodulin gene is associated with serum total and LDL cholesterol in a body size-dependent manner
Tolppanen A-M, Pulkkinen L, Kuulasmaa T, Kolehmainen M, Schwab U, Lindström J, Tuomilehto J, Uusitupa M, Kuusisto J. 2008. International journal of obesity. 32: 1868-1872 -
The genetic variation of the tenomodulin gene (TNMD) is associated with serum levels of systemic immune mediators--the Finnish Diabetes Prevention Study
Tolppanen AM, Pulkkinen L, Herder C, Koenig W, Kolehmainen M, Lindström J, Tuomilehto J, Uusitupa M. 2008. Genetics in medicine. 10: 536-544 -
Variations in the ghrelin receptor gene associate with obesity and glucose metabolism in individuals with impaired glucose tolerance
Mager U, Degenhardt T, Pulkkinen L, Kolehmainen M, Tolppanen A-M, Lindström J, Eriksson JG, Carlberg, Tuomilehto J, Uusitupa M, for the Finnish Diabetes Prevention Study Group. 2008. PLoS ONE. 3: e2941 -
Tenomodulin is associated with obesity and diabetes risk: the Finnish diabetes prevention study
Tolppanen AM, Pulkkinen L, Kolehmainen M, Schwab U, Lindström J, Tuomilehto J, Uusitupa M. 2007. Obesity. 15: 1082