Carsten Carlberg

Warwick, Timothy; Schulz, Marcel H; Guenther, Stefan; Gilsbach, Ralf; Neme, Antonio; Carlberg, Carsten; Brandes, Ralf P; Seuter, Sabine. 2021. A hierarchical regulatory network analysis of the vitamin D induced transcriptome reveals novel regulators and complete VDR dependency in monocytes Scientific reports 11 1: 6518. 2021

Hanel, Andrea; Bendik, Igor; Carlberg, Carsten. 2021. Transcriptome-Wide Profile of 25-Hydroxyvitamin D3 in Primary Immune Cells from Human Peripheral Blood Nutrients 13 11: 4100. 2021

Malmberg, Henna-Riikka; Hanel, Andrea; Taipale, Mari; Heikkinen, Sami; Carlberg, Carsten. 2021. Vitamin D Treatment Sequence Is Critical for Transcriptome Modulation of Immune Challenged Primary Human Cells Frontiers in immunology 12: 754056. 2021

Larsen, Sunniva, V; Holven, Kirsten B; Christensen, Jacob J; Flatberg, Arnar; Rundblad, Amanda; Leder, Lena; Blomhoff, Rune; Telle-Hansen, Vibeke; Kolehmainen, Marjukka; Carlberg, Carsten; Myhrstad, Mari C; Thoresen, Magne; Ulven, Stine M. 2021. Replacing Saturated Fat with Polyunsaturated Fat Modulates Peripheral Blood Mononuclear Cell Gene Expression and Pathways Related to Cardiovascular Disease Risk Using a Whole Transcriptome Approach Molecular nutrition and food research 65 24: 2100633. 2021

Zmijewski, MA; Carlberg, C. 2020. Vitamin D receptor(s): in the nucleus but also at membranes? Experimental dermatology 29 9: 876-884. 2020

Velleuer, Eunike; Carlberg, Carsten. 2020. Impact of Epigenetics on Complications of Fanconi Anemia: The Role of Vitamin D-Modulated Immunity Nutrients 12 5: 1355. 2020

Monitoring genome-wide chromatin accessibility by formaldehyde-assisted isolation of regulatory elements sequencing (FAIRE-seq). Seuter, Sabine; Neme, Antonio; Carlberg, Carsten / Epigenetics Methods. 2020. 2020

Koivisto, Oona; Hanel, Andrea; Carlberg, Carsten. 2020. Key Vitamin D Target Genes With Functions in the Immune System Nutrients 12 4: 1140. 2020

Hanel, Andrea; Neme, Antonio; Malinen, Marjo; Hämäläinen, Emmi; Malmberg, Henna-Riikka; Etheve, Stéphane; Tuomainen, Tomi-Pekka; Virtanen, Jyrki K; Bendik, Igor; Carlberg, Carsten. 2020. Common and personal target genes of the micronutrient vitamin D in primary immune cells from human peripheral blood Scientific reports 10 1: 21051. 2020

Hanel, Andrea; Carlberg, Carsten. 2020. Vitamin D and evolution: pharmacologic implications Biochemical pharmacology 173: 113595. 2020

Hanel, Andrea; Carlberg, Carsten. 2020. Skin Color and Vitamin D: An Update Experimental dermatology 29 9: 864-875. 2020

Dumo, AM; Laing, B; Lim, AG; Palaganas, E; Abad, PJ; Valdehueza, O; Palovaara, M; Saunders, H; Estola, M; Mandysova, P; Maguire, J; Ward, LD; Carlberg, C; Vehviläinen-Julkunen, K. 2020. Randomized controlled trial on the effectiveness of web-based Genomics Nursing Education Intervention for undergraduate nursing students: a study protocol Journal of advanced nursing 76 11: 3136-3146. 2020

Carlberg, Carsten; Ulven, Stine Marie; Molnár, Ferdinand (toim.). 2020. Nutrigenomics: How Science works. Springer. 2020

Carlberg, Carsten; Molnár, Ferdinand (toim.). 2020. Mechanisms of Gene Regulation: How Science works. Springer Nature. 2020

Hanel, Andrea; Malmberg, Henna-Riikka; Carlberg, Carsten. 2020. Genome-wide effects of chromatin on vitamin D signaling Journal of molecular endocrinology 64 4: R45-R56. 2020

Myhrstad, MC; de Mello, VD; Dahlman, I; Kolehmainen, M; Paananen, J; Rundblad, A; Carlberg, C; Olstad, OK; Pihlajamäki, J; Holven, KB; Hermansen, K; Dragsted, LO; Gunnarsdottir, I; Cloetens, L; Storm, MU; Åkesson, B; Rosqvist, F; Hukkanen, J; et al. (incl. Schwab, U; Uusitupa, M). 2019. Healthy Nordic Diet Modulates the Expression of Genes Related to Mitochondrial Function and Immune Response in Peripheral Blood Mononuclear Cells from Subjects with the Metabolic Syndrome - A SYSDIET Sub-Study Molecular nutrition and food research 63 13: 1801405. 2019

Ulven, SM; Holven, KB; Rundblad, A; Myhrstad, MCW; Leder, L; Dahlman, I; Mello, VD; Schwab, U; Carlberg, C; Pihlajamäki, J; Hermansen, K; Dragsted, LO; Gunnarsdottir, I; Cloetens, L; Åkesson, B; Rosqvist, F; Hukkanen, J; Herzig, KH; Savolainen, MJ; Risérus, U; et al. [incl. Uusitupa, M]. 2019. An Isocaloric Nordic Diet Modulates RELA and TNFRSF1A Gene Expression in Peripheral Blood Mononuclear Cells in Individuals with Metabolic Syndrome-A SYSDIET Sub-Study Nutrients 11 12: 2932. 2019

Nurminen, V; Seuter, S; Carlberg, C. 2019. Primary Vitamin D Target Genes of Human Monocytes Frontiers in physiology 10: 194. 2019

Neme, Antonio; Seuter, Sabine; Malinen, Marjo; Nurmi, Tarja; Tuomainen, Tomi-Pekka; Virtanen, Jyrki K; Carlberg, Carsten. 2019. In vivo transcriptome changes of human white blood cells in response to vitamin D Journal of steroid biochemistry and molecular biology 188: 71-76. 2019

Fleet, JC; Campbell, MJ; Carlberg, C; Demay, MB; Ebeling, PR; Schoenmakers, I; White, JH; Welsh, J; Hewison, M. 2019. Highlights from the 21st Workshop on Vitamin D in Barcelona, May 2018 Journal of steroid biochemistry and molecular biology 189: 210-217. 2019

Maestro, Miguel A; Molnár, Ferdinand; Carlberg, Carsten. 2019. Vitamin D and Its Synthetic Analogs Journal of medicinal chemistry 62 15: 6854-6875. 2019

Carlberg, Carsten. 2019. Vitamin D: A Micronutrient Regulating Genes Current pharmaceutical design 25 15: 1740-1746. 2019

Carlberg, Carsten. 2019. Vitamin D Signaling in the Context of Innate Immunity: Focus on Human Monocytes Frontiers in immunology 10: 2211. 2019

Carlberg, Carsten. 2019. Nutrigenomics of Vitamin D Nutrients 11 3: 676. 2019

Fleet, JC; Kovalenko, PL; Li, Y; Smolinski, J; Spees, C; Yu, JG; Thomas-Ahner, JM; Cui, M; Neme, A; Carlberg, C; Clinton, SK. 2019. Vitamin D Signaling Suppresses Early Prostate Carcinogenesis in TgAPT121 Mice Cancer prevention research 12 6: 343-356. 2019

Nurminen, Veijo; Neme, Antonio; Seuter, Sabine; Carlberg, Carsten. 2018. The impact of the vitamin D-modulated epigenome on VDR target gene regulation BIOCHIMICA ET BIOPHYSICA ACTA - GENE REGULATORY MECHANISMS 1861 8: 697-705. 2018

Vitamin D. Carlberg, Carsten / Encyclopedia of Life Sciences (eLS). 2018. 2018

Seuter, Sabine; Neme, Antonie; Carlberg, Carsten. 2018. ETS transcription factor family member GABPA contributes to vitamin D receptor target gene regulation Journal of steroid biochemistry and molecular biology 177: 46-52. 2018

Nurminen, Veijo; Neme, Antonio; Seuter, Sabine; Carlberg, Carsten. 2018. Modulation of vitamin D signaling by the pioneer factor CEBPA Biochimica et biophysica acta: gene regulatory mechanisms 2019; 1862 1: 96-106. 2018

Carlberg, Carsten; Seuter, Sabine; Nurmi, Tarja; Tuomainen, Tomi-Pekka; Virtanen, Jyrki K; Neme, Antonio. 2018. In vivo response of the human epigenome to vitamin D: A proof-of-principle study Journal of steroid biochemistry and molecular biology 180: 142-148. 2018

Haq, Afrozul; Wimalawansa, Sunil J; Carlberg, Carsten. 2018. Highlights from the 6th International Conference on Vitamin D Deficiency, "Nutrition and Human Health", Abu Dhabi, United Arab Emirates, March 9-10, 2017 Journal of steroid biochemistry and molecular biology 180: 1-3. 2018

Carlberg, Carsten; Neme, Antonio. 2018. A Machine learning approaches infer vitamin D signaling: Critical impact of vitamin D receptor binding within topologically associated domains JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY 2019; 15: 103-109. 2018

Carlberg, Carsten; Molnár, Ferdinand (toim.). 2018. Human Epigenomics. Springer. 2018

Carlberg, Carsten. 2018. Vitamin D Genomics: From In Vitro to In Vivo. FRONTIERS IN ENDOCRINOLOGY 9: 250. 2018

Singh PK, van den Berg PR, Long MD, Vreugdenhil A, Grieshober L, Ochs-Balcom HM, Wang J, Delcambre S, Heikkinen S, Carlberg C, Campbell MJ, Sucheston-Campbell LE. 2017. Integration of VDR genome wide binding and GWAS genetic variation data reveals co-occurrence of VDR and NF-kappaB binding that is linked to immune phenotypes. BMC Genomics 18 1: -. 2017

Seuter Sabine, Virtanen Jyrki K, Nurmi Tarja, Pihlajamäki Jussi, Mursu Jaakko, Voutilainen Sari, Tuomainen Tomi-Pekka, Neme Antonio, Carlberg Carsten. 2017. Molecular evaluation of vitamin D responsiveness of healthy young adults. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY 174: 314-321. 2017

Seuter S, Neme A, Carlberg C. 2017. Epigenomic PU.1-VDR crosstalk modulates vitamin D signaling. BIOCHIMICA ET BIOPHYSICA ACTA - GENE REGULATORY MECHANISMS 1860 4: 405-415. 2017

Neme Antonio, Seuter Sabine, Carlberg Carsten. 2017. Selective regulation of biological processes by vitamin D based on the spatio-temporal cistrome of its receptor. BIOCHIMICA ET BIOPHYSICA ACTA - GENE REGULATORY MECHANISMS 1860 9: 952-961. 2017

Haq A, Wimalawansa SJ, Carlberg C. 2017. Highlights from the 5th International Conference on Vitamin D Deficiency, Nutrition and Human Health, Abu Dhabi, United Arab Emirates, March 24-25, 2016. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY 175: 1-3. 2017

Carlberg Carsten. 2017. Molecular endocrinology of vitamin D on the epigenome level. MOLECULAR AND CELLULAR ENDOCRINOLOGY 453: 14-21. 2017

Carlberg Carsten. 2017. Endocrine functions of vitamin D. MOLECULAR AND CELLULAR ENDOCRINOLOGY 453: 1-2. 2017

Carlberg Carsten, Haq Afrozul. 2017. The concept of the personal vitamin D response index. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY 2018; 175: 12-17. 2017

Carlberg Carsten. 2017. Vitamin D and chromatin. Teoksessa: Feldman David, Pike J Wesley, Bouillon Roger, Giovannucci Edward, Goltzman David, Hewison Martin (toim.) Vitamin D. 4th Edition. Volume 1: Biochemistry, Physiology and Diagnostics. Elsevier. s. 217-226. 2017

Carlberg Carsten. 2016. Vitamin D. Teoksessa: Caplan Michael (toim.) Reference Module in Biomedical Sciences. Elsevier. s. -. 2016

Kreienkamp Ray, Croke Monica, Neumann Martin A, Bedia-Diaz Gonzalo, Graziano Simona, Dusso Adriana, Dorsett Dale, Carlberg Carsten, Gonzalo Susana. 2016. Vitamin D receptor signaling improves Hutchinson-Gilford progeria syndrome cellular phenotypes. Oncotarget 7 21: 30018-30031. 2016

Leder Lena, Kolehmainen Marjukka, Narverud Ingunn, Dahlman Ingrid, Myhrstad Mari CW, de Mello Vanessa D, Paananen Jussi, Carlberg Castren, Schwab Ursula, Herzig Karl-Heinz, Cloetens Lieselotte, Storm Matilda Ulmius, Hukkanen Janne, Savolainen Markku J, Rosqvist Fredrik, Hermansen Kjeld, Dragsted Lars O, Gunnarsdottir Ingibjörk, Thorsdottir Inga, Risérus Ulf et al.. 2016. Effects of a healthy Nordic diet on gene expression changes in peripheral blood mononuclear cells in response to an oral glucose tolerance test in subjects with metabolic syndrome: a SYSDIET sub-study. Genes and Nutrition 11 3: 1-13. 2016

Maestro Miguel A, Molnár Ferdinand, Mouriño Antonio, Carlberg Carsten. 2016. Vitamin D receptor 2016: novel ligands and structural insights. EXPERT OPINION ON THERAPEUTIC PATENTS 26 11: 1291-1306. 2016

Mechanisms of gene regulation (2. ed). Carlberg Carsten, Molnár Ferdinand. 2016 2016

Neme Antonio, Seuter Sabine, Carlberg Carsten. 2016. Vitamin D-dependent chromatin association of CTCF in human monocytes. BIOCHIMICA ET BIOPHYSICA ACTA - GENE REGULATORY MECHANISMS 1859 11: 1380-1388. 2016

Nutrigenomics. Carlberg Carsten, Ulven Stine Marie, Molnár Ferdinand. 2016 2016

Seuter Sabine, Neme Antonio, Carlberg Carsten. 2015. Epigenome-wide effects of vitamin D and their impact on the transcriptome of human monocytes involve CTCF. NUCLEIC ACIDS RESEARCH 2016; 44 9: 4090-4104. 2015

Vukic Maja, Neme Antonio, Seuter Sabine, Saksa Noora, de Mello Vanessa DF, Nurmi Tarja, Uusitupa Matti, Tuomainen Tomi-Pekka, Virtanen Jyrki K, Carlberg Carsten. 2015. Relevance of Vitamin D Receptor Target Genes for Monitoring the Vitamin D Responsiveness of Primary Human Cells. PLOS ONE [ONLINE] 10 4: e0124339. 2015

Carlberg Carsten, Molnár Ferdinand. 2015. Vitamin D receptor signaling and its therapeutic implications: Genome-wide and structural view. CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY 93 5: 311-318. 2015

Rybakova Katja N, Bruggeman Frank J, Tomaszewska Aleksandra, Moné Martijn J, Carlberg Carsten, Westerfoff Hans V. 2015. Multiplex Eukaryotic Transcription (In) activation: Timing, Bursting and Cycling of a Ratchet Clock Mechanism. PLOS COMPUTATIONAL BIOLOGY 11 4: e1004236. 2015

Neme Antonio, Nurminen Veijo, Seuter Sabine, Carlberg Carsten. 2015. The vitamin D-dependent transcriptome of human monocytes. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY 2016; 164: 180-187. 2015

Carlberg Carsten. 2015. Molecular approaches for optimizing vitamin D supplementation. VITAMINS AND HORMONES 2016; 100: 255-271. 2015

Wilfinger Julia, Seuter Sabine, Tuomainen Tomi-Pekka, Virtanen Jyrki K, Voutilainen Sari, Nurmi Tarja, de Mello Vanessa DF, Uusitupa Matti, Carlberg Carsten. 2014. Primary vitamin D receptor target genes as biomarkers for the vitamin D3 status in the hematopoietic system. JOURNAL OF NUTRITIONAL BIOCHEMISTRY 25 8: 875-884. 2014

Tuoresmäki Pauli, Väisänen Sami, Neme Antonio, Heikkinen Sami, Carlberg Carsten. 2014. Patterns of Genome-Wide VDR Locations. PLOS ONE [ONLINE] 9 4: e96105. 2014

Seuter Sabine, Neme Antonio, Carlberg Carsten. 2014. Characterization of genomic vitamin D receptor binding sites through chromatin looping and opening. PLOS ONE [ONLINE] 9 4: e96184. 2014

Rybakova Katja N, Tomaszewska Aleksandra, van Mourik Simon, Blom Joke, Westerhoff Hans V, Carlberg Carsten, Bruggeman Frank J. 2014. Tracing the molecular basis of transcriptional dynamics in noisy data by using an experiment-based mathematical model. NUCLEIC ACIDS RESEARCH Epub ahead of print: -. 2014

Saksa Noora, Neme Antonio, Ryynänen Jussi, Uusitupa Matti, de Mello Vanessa DF, Voutilainen Sari, Nurmi Tarja, Virtanen Jyrki K, Tuomainen Tomi-Pekka, Carlberg Carsten. 2014. Dissecting high from low responders in a vitamin D3 intervention study. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY Epub ahead of print: -. 2014

Ryynänen Jussi, Neme Antonio, Tuomainen Tomi-Pekka, Virtanen Jyrki K, Voutilainen Sari, Nurmi Tarja, de Mello Vanessa DF, Uusitupa Matti, Carlberg Carsten. 2014. Changes in vitamin D target gene expression in adipose tissue monitor the vitamin D response of human individuals. Molecular Nutrition & Food Research 58: 2036-2045. 2014

Carlberg Carsten. 2014. The physiology of vitamin D - far more than calcium and bone. Frontiers in Physiology 5 335: -. 2014

Nurminen Veijo, Neme Antonio, Ryynänen Jussi, Heikkinen Sami, Seuter Sabine, Carlberg Carsten. 2014. The transcriptional regulator BCL6 participates in the secondary gene regulatory response to vitamin D. BIOCHIMICA ET BIOPHYSICA ACTA - GENE REGULATORY MECHANISMS Epub ahead of print: -. 2014

Kolehmainen Marjukka, Ulven Stine M, Paananen Jussi, de Mello Vanessa, Schwab Ursula, Carlberg Carsten, Myhrstad Mari, Pihlajamäki Jussi, Dungner Elisabeth, Sjölin Eva, Gunnarsdottir Ingibjörg, Cloetens Lieselotte, Landin-Olsson Mona, Akesson Björn, Rosqvist Fredrik, Hukkanen Janne, Herzig Karl-Heinz, Dragsted Lars O, Savolainen Markku J, Brader Lea, Hermansen Kjeld, Risérus Ulf, Thorsdottir Inga,. 2014. Healthy Nordic diet downregulates the expression of genes involved in inflammation in subcutaneous adipose tissue in individuals with features of the metabolic syndrome. AMERICAN JOURNAL OF CLINICAL NUTRITION 101 1 (2015): 228-239. 2014

Carlberg Carsten. 2014. What Do We Learn from the Genome-wide Perspective on Vitamin D3?. ANTICANCER RESEARCH 48 4: 217-218. 2014

Carlberg Carsten. 2014. Genome-wide (over)view on the actions of vitamin D. Frontiers in Physiology 5 164: 1-10. 2014

Carlberg Carsten, Raunio Hannu. 2014. From pharmacogenomics to integrated personal omics profiling: a gap in implementation into healthcare. Personalized Medicine 11 7: 625-629. 2014

Brader Lea, Rejnmark Lars, Carlberg Carsten, Schwab Ursula, Kolehmainen Marjukka, Rosqvist Fredrik, Cloetens Lieselotte, Landin-Olsson Mona, Gunnarsdottir Ingibjorg, Poutanen Kaisa S, Herzig Karl-Heinz, Risérus Ulf, Savolainen Markku J, Thorsdottir Inga, Uusitupa Matti, Hermansen Kjeld. 2014. Effects of a healthy Nordic diet on plasma 25-hydroxyvitamin D concentration in subjects with metabolic syndrome: a randomized, placebo-controlled trial (SYSDIET). EUROPEAN JOURNAL OF NUTRITION 53 4: 1123-34. 2014

Mechanisms of Gene Regulation. Carlberg Carsten, Molnár Ferdinand. 2014 2014

Seuter S, Pehkonen P, Heikkinen S, Carlberg C. 2013. Dynamics of 1α,25-dihydroxyvitamin D3-dependent chromatin accessibility of early vitamin D receptor target genes. BIOCHIMICA ET BIOPHYSICA ACTA 1829: 1266-1275. 2013

Seuter S, Ryynänen J, Carlberg C. 2013. The ASAP2 gene is a primary target of 1,25-dihydroxyvitamin D3 in human monocytes and macrophages. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY [Epub ahead of print]: x-x. 2013

Carlberg C, Seuter S, de Mello VDF, Schwab U, Voutilainen S, Pulkki K, Nurmi T, Virtanen J, Tuomainen T-P, Uusitupa M. 2013. Primary vitamin D target genes allow a categorization of possible benefits of vitamin D3 supplementation. PLOS ONE [ONLINE] 8 7: e71042. 2013

Ryynänen J, Seuter S, Campbell MJ, Carlberg C. 2013. Gene Regulatory Scenarios of Primary 1,25-Dihydroxyvitamin D3 Target Genes in a Human Myeloid Leukemia Cell Line. Cancers 5: 1221-1241. 2013

Ryynänen J, Carlberg C. 2013. Primary 1,25-Dihydroxyvitamin D3 Response of the Interleukin 8 Gene Cluster in Human Monocyte- and Macrophage-Like Cells. PLOS ONE [ONLINE] 8 10: e78170. 2013

Carlberg C, Campbell MJ. 2013. Vitamin D receptor signaling mechanisms: Integrated actions of a well-defined transcription factor. STEROIDS (NEW YORK NY) 78: 127-136. 2013

Seuter S, Pehkonen P, Heikkinen S, Carlberg C. 2012. The gene for the transcription factor BHLHE40/DEC1/stra13 is a dynamically regulated primary target of the vitamin D receptor. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY online [Epub ahead of print]: -. 2012

Seuter S, Heikkinen S, Carlberg C. 2012. Chromatin acetylation at transcription start sites and vitamin D receptor binding regions relates to effects of 1alfa,25-dihydroxyvitamin D3 and histone deacetylase inhibitors on gene expression. NUCLEIC ACIDS RESEARCH -: -. 2012

Pehkonen P, Welter-Stahl L, Diwo J, Ryynänen J, Wienecke-Baldacchino A, Heikkinen S, Treuter E, Steffensen K, Carlberg C. 2012. Genome-wide landscape of liver X receptor chromatin binding and gene regulation in human macrophages. BMC GENOMICS [ONLINE:HTTP://WWW.BIOMEDCENTRAL.COM/BMCGENOMICS/] 13 50: -. 2012

Lorente-Cebrián S, Eriksson A, Dunlop T, Mejhert N, Dahlman I, Åström G, Sjölin E, Wåhlén K, Carlberg C, Laurencikiene J, Hedén P, Arner P, Rydén M. 2012. Differential effects of 1alfa,25-dihydroxycholecalciferol on MCP-1 and adiponectin production in human white adipocytes. EUROPEAN JOURNAL OF NUTRITION 51: 335-342. 2012

Mutt SJ, Karhu T, Lehtonen S, Lehenkari P, Carlberg C, Saarnio J, Sebert S, Hyppönen E, Järvelin M-R, Herzig K-H. 2012. Inhibition of cytokine secretion from adipocytes by 1,25-dihydroxyvitamin D3 via the NF-kappaB pathway. FASEB JOURNAL 26: 4400-4407. 2012

John E, Wienecke-Baldacchino A, Liivrand M, Heinäniemi M, Carlberg C, Sinkkonen L. 2012. Dataset integration identifies transcriptional regulation of microRNA genes by PPARgamma in differentiating mouse 3T3-L1 adipocytes. NUCLEIC ACIDS RESEARCH 40 10: 4446-4460. 2012

Carlberg Carsten, Molnár Ferdinand, Mouriño Antonio. 2012. Vitamin D receptor ligands: the impact of crystal structures. EXPERT OPINION ON THERAPEUTIC PATENTS 22 4: 417-435. 2012

Carlberg C. 2012. The need for education in personalized medicine. Personalized Medicine 9 2: 147-150. 2012

Carlberg C, Seuter S, Heikkinen S. 2012. The First Genome-wide View of Vitamin D Receptor Locations and Their Mechanistic Implications. ANTICANCER RESEARCH 32 1: 271-282. 2012

Carlberg Carsten, Molnár Ferdinand. 2012. Current status of vitamin D signaling and its therapeutic applications CURRENT TOPICS IN MEDICINAL CHEMISTRY 12 6: 528-547. 2012

Kriebitzsch C, Verlinden L, Eelen G, van Schoor NM, Swart K, Lips P, Meyer MB, Pike JW, Boonen S, Carlberg C, Vitvitsky V, Bouillon R, Banerjee R, Verstuyf A. 2011. 1,25-Dihydroxyvitamin D(3) Influences Cellular Homocystine Levels in Murine Preosteoplastic MC3T3-E1 Cells by Directs Regulation of Cystathionine beta-Synthase JOURNAL OF BONE AND MINERAL RESEARCH 26 12: 2991-2000. 2011

Väisänen Sami, Matilainen Juha, Carlberg Carsten. 2011. Dynamic nature of transcriptional regulation of nuclear receptor target genes in the context of chromatin organization. Dermato-Endocrinology 3 3: 1-5. 2011

Malinen Marjo, Ryynänen Jussi, Heinniemi Merja, Sami Väisänen Sami, Carlberg Carsten. 2011. Cyclical regulation of the insulin-like growth factor binding protein 3 gene in response to 1alpha,25-dihydroxyvitamin D3. NUCLEIC ACIDS RESEARCH 39 2: 502-512. 2011

Kansanen Emilia, Bonacci Gustavo, Schopfer Francisco J, Kuosmanen Suvi M, Tong Kit I, Leinonen Hanna, Woodcock Steven R, Yamamoto Masayuk, Carlberg Carsten, Ylä-Herttuala Seppo, Freeman Bruce A, Levonen Anna-Liisa. 2011. Electrophilic nitro-fatty acids activate NRF2 by a KEAP1 cysteine 151-independent mechanism. JOURNAL OF BIOLOGICAL CHEMISTRY 286: 14019-14027. 2011

Heikkinen Sami, Väisänen Sami, Pehkonen Petri, Seuter Sabine, Benes Vladimir, Carlberg Carsten. 2011. Nuclear hormone 1α,25-dihydroxyvitamin D3 elicits a genome-wide shift in the locations of VDR chromatin occupancy. NUCLEIC ACIDS RESEARCH 39 21: 9181-9193. 2011

Gynther Petra, Toropainen Sari, Matilainen Juha M, Seuter Sabine, Carlberg Carsten, Väisänen Sami. 2011. Mechanism of 1α,25-dihydroxyvitamin D3-dependent repression of interleukin-12B. BIOCHIMICA ET BIOPHYSICA ACTA - MOLECULAR CELL RESEARCH 1813 5: 810-818. 2011

Carlberg Carsten. 2011. Target genes of vitamin D: Spatio-temporal interaction of chromatin, VDR and response elements: Feldman David, Pike J. Wesley, Adams John S., Vitamin D, Third Edition. 211-226. 2011

Lahnalampi Mari, Heinäniemi Merja, Sinkkonen Lasse, Wabitsch Martin, Carlberg Carsten. 2010. Time-resolved expression profiling of the nuclear receptor superfamily in human adipogenesis. PLOS ONE [ONLINE] 5 9: -. 2010

Venäläinen, T., Molnár, F., Oostenbrink, C., Carlberg, C. and Peräkylä M.. 2010. Molecular Mechanism of Allosteric Communication in the human PPAR alpha -RXR alpha Heterodimer. PROTEINS: STRUCTURE, FUNCTION, AND BIOINFORMATICS 78: 873-887. 2010

Sari Toropainen, Sami Väisänen, Sami Heikkinen,Carsten Carlberg. 2010. The Down-regulation of the Human MYC Gene by the Nuclear Hormone 1α,25-dihydroxyvitamin D3 is Associated with Cycling of Corepressors and Histone Deacetylases. JOURNAL OF MOLECULAR BIOLOGY 400 3: 284-294. 2010

Matilainen JM, Malinen M, Turunen MM, Carlberg C, Väisänen S. 2010. The number of vitamin D receptor binding sites defines the different vitamin D responsiveness of the CYP24 gene in malignant and normal mammary cells.. JOURNAL OF BIOLOGICAL CHEMISTRY 285 31: 24174-24183. 2010

Matilainen JM, Husso T, Toropainen S, Seuter S, Turunen MP, Gynther P, Ylä-Herttuala S, Carlberg C, Väisänen S.. 2010. Primary effect of 1α,25(OH)(2)D(3) on IL-10 expression in monocytes is short-term down-regulation. BIOCHIMICA ET BIOPHYSICA ACTA - MOLECULAR CELL RESEARCH 1803 11: 1276-1286. 2010

Lou, Y-R., Molnár, F., Peräkylä, M., Qiao, S., Kalueff, A.V., St-Arnaud, R., Carlberg, C. and Tuohimaa, P.. 2010. 25-Hydroxyvitamin D3 is an Agonistic Vitamin D Receptor Ligand. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY 118: 162-170. 2010

Kolodkin AN, Frank J, Bruggeman FJ, Plant N, Moné MJ, Bakker B, Campbell MJ, van Leeuwen JPTM, Carlberg C, Snoep JL, Westerhoff HV. 2010. Design principles of nuclear receptor signaling: how complex networking improves signal transduction. MOLECULAR SYSTEMS BIOLOGY (ONLINE) 6: -. 2010

Carlberg, Carsten, Heinäniemi Merja. 2010. The impact of whole genome in silico screening for nuclear receptor binding sites in systems biology: Lodhi Huma M, Muggleton Stephen H (editors), Elements of Computational Systems Biology.Wiley. 309-324. 2010

Carlberg Carsten. 2010. The impact of transcriptional cycling on gene regulation. Transcription 1: 13-16. 2010

Carlberg Carsten. 2010. New Insights to nuclear receptor gene regulation from analysis of their response elements in target genes. Teoksessa: Bunce CM, Campbell MJ (editors) (toim.), Nuclear Receptors, Proteins and Cell Regulation.Springer. ss. 419-437. 2010

Carlberg Carsten. 2010. Diversity of vitamin D target genes: Holick MF (ed), Nutrition and Health: Vitamin D, 2nd Edition.Humana Press. 255-274. 2010

Carlberg Carsten, Seuter Sabine. 2010. Dynamics of nuclear receptor target gene regulation. CHROMOSOMA 119 5: 479-484. 2010

Makkonen KM, Malinen M, Ropponen A, Väisänen S, Carlberg C. 2009. Cell cycle regulatory effects of retinoid acid and forskolin are mediated by the Cyclin C gene. JOURNAL OF MOLECULAR BIOLOGY 393: 261-271. 2009

Saramäki A, Diermeier S, Kellner R, Laitinen H, Väisänen S, Carlberg C. 2009. Cyclical chromatin looping and transcription factor association on the regulatory regions of the p21 (CDKN1A) gene in response to 1[alpha],25-dihydroxyvitamin D3. JOURNAL OF BIOLOGICAL CHEMISTRY 284 12: 8073-8082. 2009

Makkonen KM, Pasonen-Seppänen S, Törrönen K, Tammi MI, Carlberg C. 2009. Regulation of the hyaluronan synthase 2 gene by convergence in cyclic AMP response element-binding protein and retinoid acid receptor signaling. JOURNAL OF BIOLOGICAL CHEMISTRY 284 27: 18270-18281. 2009

Degenhardt T, Väisänen S, Rakhshandehroo M, Kersten S, Carlberg C. 2009. Peroxisome proliferator-activated receptor [alpha] controls hepatic heme biosynthesis throught ALAS1 JOURNAL OF MOLECULAR BIOLOGY 388: 225-238. 2009

Degenhardt T, Rybakova KN, Tomaszewska A, Moné MJ, Westerhoff HV, Bruggeman FJ, Carlberg C. 2009. Population-level transcription cycles derive from stochastic timing of single-cell transcription. CELL 138: 489-501. 2009

Carlberg C, Seuter S. 2009. A genomic perspective on vitamin D signaling. ANTICANCER RESEARCH 29: 3485-3494. 2009

Campbell MJ, Carlberg C, Koeffler HP. 2008. A role for the PPARgamma in cancer therapy. PPAR RESEARCH [ONLINE] 314974: 17 s. 2008

Heinäniemi M, Carlberg C. 2008. Screening for PPAR responsive regulatory modules in cancer. PPAR RESEARCH [ONLINE] 2008 749073: 8 s. 2008

Mager U, Degenhardt T, Pulkkinen L, Kolehmainen M, Tolppanen A-M, Lindström J, Eriksson JG, Carlberg, Tuomilehto J, Uusitupa M, for the Finnish Diabetes Prevention Study Group. 2008. Variations in the ghrelin receptor gene associate with obesity and glucose metabolism in individuals with impaired glucose tolerance PLOS ONE [ONLINE] 3 8: e2941. 2008

Malinen M, Saramäki A, Ropponen A, Degenhardt T, Väisänen S, Carlberg C. 2008. Distinct HDACs regulate the transcriptional response of human cyclin-dependent kinase inhibitor genes to trichostatin A and 1alpha,25-dihydroxyvitamin D3. NUCLEIC ACIDS RESEARCH 36 1: 121-132. 2008

Pendás-Franco N, García JM, Peña C, Valle N, Pálmer HG, Heinäniemi M, Carlberg C, Jiménez B, Bonilla F, Muñoz A, González-Sancho JM. 2008. DICKKOPF-4 is induced by TCF/beta-catenin and upregulated in human colon cancer, promotes tumour cell invasion and angiogenesis and is repressed by 1alpha,25-dihydroxyvitamin D3. ONCOGENE (LONDON) 27: 4467-4477. 2008

Reichrath J, Lehmann B, Carlberg C, Varani J, Zouboulis CC. 2007. Vitamins as hormones. HORMONE AND METABOLIC RESEARCH 39: 71-84. 2007

Seuter S, Väisänen S, Rådmark O, Carlberg C, Steinhilber D. 2007. Functional characterization of vitamin D responding regions in the human 5-lipoxygenase gene. BIOCHIMICA ET BIOPHYSICA ACTA 1771: 864-872. 2007

Saavalainen K, Tammi MI, Bowen T, Lienhard Schmitz M, Carlberg C. 2007. Integration of the activation of the human hyaluronan synthase 2 gene promoter by common cofactors of the transcription factors retinoic acid receptor and nuclear factor kappaB. JOURNAL OF BIOLOGICAL CHEMISTRY 282 15: 11530-11539. 2007

Turunen MM, Dunlop TW, Carlberg C, Väisänen S. 2007. Selective use of multiple vitamin D response elements underlies the 1alpha,25-dihydroxyvitamin D3-mediated negative regulation of the human CYP27B1 gene. NUCLEIC ACIDS RESEARCH 35 8: 2734-2747. 2007

Lee SS, Crabb SJ, Janghra N, Carlberg C, Williams AC, Cutress RI, Packham G, Hague A. 2007. Subcellular localisation of BAG-1 and its regulation of vitamin D receptor-mediated transactivation and involucrin expression in oral keratinocytes: implications for oral carcinogenesis. EXPERIMENTAL CELL RESEARCH 313: 3222-3238. 2007

Degenhardt T, Saramäki A, Malinen M, Rieck M, Väisänen S, Huotari A, Herzig K-H, Müller R, Carlberg C. 2007. Three members of the human pyruvate dehydrogenase kinase gene family are direct targets of the peroxisome proliferator-activated receptor beta/delta. JOURNAL OF MOLECULAR BIOLOGY 372 2: 341-355. 2007

Carlberg C, Seuter S. 2007. The vitamin D receptor. DERMATOLOGIC CLINICS 25: 515-523. 2007

Carlberg C, Dunlop TW, Saramäki A, Sinkkonen L, Matilainen M, Väisänen S. 2007. Controlling the chromatin organization of vitamin D target genes by multiple vitamin D receptor binding sites. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY 103: 338-343. 2007

Heinäniemi M, Uski JO, Degenhardt T, Carlberg C. 2007. Meta-analysis of primary target genes of peroxisome proliferator-activated receptors GENOME BIOLOGY [ONLINE] 8: R147. 2007

Molnár F, Peräkylä M, Carlberg C. 2006. Vitamin D receptor agonists specifically modulate the volume of the ligand-binding pocket JOURNAL OF BIOLOGICAL CHEMISTRY 281 15: 10516-10526. 2006

Sorg BL, Klan N, Seuter S, Dishart D, Rådmark O, Habenicht A, Carlberg C, Werz O, Steinhilber D. 2006. Analysis of the 5-lipoxygenase promoter and characterization of a vitamin D receptor binding site. BIOCHIMICA ET BIOPHYSICA ACTA 1761: 686-697. 2006

Saramäki A, Banwell CM, Campbell MJ, Carlberg C. 2006. Regulation of the human p21(waf1/cip1) gene promoter via multiple binding sites for p53 and the vitamin D3 receptor. NUCLEIC ACIDS RESEARCH 34 2: 543-554. 2006

Molnar Ferdinand, Peräkylä Mikael, Carlberg Carsten. 2006. Vitamin D Receptor Agonists Specifically Modulate the Volume of the Ligand-Binding Pocket JOURNAL OF BIOLOGICAL CHEMISTRY 281 15: 10516-10526. 2006

Degenhardt T, Matilainen M, Herzig K-H, Dunlop TW, Carlberg C. 2006. The insulin-like growth factor-binding protein 1 gene is a primary target of peroxisome proliferator-activated receptors. JOURNAL OF BIOLOGICAL CHEMISTRY 281 51: 39607-39619. 2006

Carlberg C, Molnar F. 2006. Detailed molecular understanding of agonistic and antagonistic vitamin D receptor ligands. CURRENT TOPICS IN MEDICINAL CHEMISTRY 6 12: 1243-53. 2006

Carlberg C, Dunlop TW. 2006. The impact of chromatin organization of vitamin D target genes. ANTICANCER RESEARCH 26: 2637-2646. 2006

Carlberg C, Dunlop TW. 2006. An integrated biological approach to nuclear receptor signaling in physiological control and disease. CRITICAL REVIEWS IN EUKARYOTIC GENE EXPRESSION 16 1: 1-22. 2006

Abedin SA, Banwell CM, Colston KW, Carlberg C, Campbell MJ. 2006. Epigenetic corruption of VDR signalling in malignancy ANTICANCER RESEARCH 26: 2557-2566. 2006

Molnár F, Matilainen M, Carlberg C. 2005. Structural determinants of the agonist-independent association of human peroxisome proliferator-activated receptors with coactivators. JOURNAL OF BIOLOGICAL CHEMISTRY 280 28: 26543-26556. 2005

Sinkkonen L, Malinen M, Saavalainen K, Väisänen S, Carlberg C. 2005. Regulation of the human cyclin C gene via multiple vitamin D3-responsive regions in its promoter NUCLEIC ACIDS RESEARCH 33 8: 2440-2451. 2005

Saavalainen K, Pasonen-Seppänen S, Dunlop TW, Tammi R, Tammi MI, Carlberg C. 2005. The human hyaluronan synthase 2 gene is a primary retinoic acid and epidermal growth factor responding gene. JOURNAL OF BIOLOGICAL CHEMISTRY 280 15: 14636-14644. 2005

Peräkylä M, Malinen M, Herzig K-H, Carlberg C. 2005. Gene regulatory potential of nonsteroidal vitamin D receptor ligands. MOLECULAR ENDOCRINOLOGY 19 8: 2060-2073. 2005

Väisänen S, Dunlop TW, Sinkkonen L, Frank C, Carlberg C. 2005. Spatio-temporal activation of chromatin on the human CYP24 gene promoter in the presence of 1[alpha],25-dihydroxyvitamin D3. JOURNAL OF MOLECULAR BIOLOGY 350: 65-77. 2005

Matilainen M, Malinen M, Saavalainen K, Carlberg C. 2005. Regulation of multiple insulin-like growth factor binding protein genes by 1[alpha],25-dihydroxyvitamin D3. NUCLEIC ACIDS RESEARCH 33 17: 5521-5532. 2005

Kobayashi H, Kromminga A, Dunlop TW, Tychsen B, Conrad F, Suzuki N, Memezava A, Bettermann A, Aiba S, Carlberg C, Paus R. 2005. A role of melatonin in neuroectodermal-mesodermal interactions: the hair follicle synthesizes melatonin and expresses functional melatonin receptors. FASEB JOURNAL 19 12: 1710-1712. 2005

Frank C, Makkonen H, Dunlop TW, Matilainen M, Väisänen S, Carlberg C. 2005. Identification of pregnane X reseptor binding sites in the regulatory regions of genes involved in bile acid homeostasis JOURNAL OF MOLECULAR BIOLOGY 346: 506-519. 2005

Dunlop T, Väisänen S, Frank C, Molnár F, Sinkkonen L, Carlberg C. 2005. The human peroxisome proliferator-activated receptor [delta] gene is a primary target of 1[alpha],25-dihydroxyvitamin D3 and its nuclear receptor JOURNAL OF MOLECULAR BIOLOGY 349: 248-260. 2005

Carlberg C, Dunlop TW, Frank C, Väisänen S. 2005. Molecular basis of the diversity of vitamin D target genes: Feldman D, Wesley Pike J, Glorieux FH, Vitamin D.Elsevier Academic Press. 313-325. 2005

Lempiäinen H, Molnár F, Macias Gonzalez M, Peräkylä M, Carlberg C. 2005. Antagonist- and inverse agonist-driven interactions of the vitamin D receptor and the constitutive androstane receptor with corepressor protein. MOLECULAR ENDOCRINOLOGY 19 9: 2258-2272. 2005

Carlberg C. 2004. Ligand-mediated conformational changes of the VDR are required for gene transactivation JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY 89-90: 227-232. 2004

Carlberg C. 2004. Principles of gene regulation by bioactive lipids through members of the nuclear receptor family: Schmitz ML, Bacher S, Mechanisms of Signal Transduction and Inducible Gene Expression.Research signpost. 77-95. 2004

Dunlop TW, Väisänen S, Frank C, Carlberg C. 2004. The genes of the coactivator TIF2 and the corepressor SMRT are primary 1alfa,25(OH)2D3 targets. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY 89-90: 257-260. 2004

Frank C, Molnar F, Matilainen M, Lempiäinen H, Carlberg C. 2004. Agonist-dependent and agonist-independent transactivations of the human constitutive androstane receptor are modulated by specific amino acid pairs. JOURNAL OF BIOLOGICAL CHEMISTRY 279 32: 33558-33566. 2004

Moehren U, Dressel U, Reeb CA, Väisänen S, Dunlop TW, Carlberg C, Baniahmad A. 2004. The highly conserved region of the co-repressor Sin3A functionally interacts with the co-repressor alien NUCLEIC ACIDS RESEARCH 32 10: 2995-3004. 2004

Peräkylä M, Molnar F, Carlberg C. 2004. A structural basis for the species-specific antagonism of 26,23-lactones on vitamin D signaling. CHEMISTRY AND BIOLOGY 11: 1147-1156. 2004

Väisänen S, Dunlop TW, Frank C, Carlberg C. 2004. Using chromatin immunoprecipitation to monitor 1alfa,25-dihydroxyvitamin D3-dependent chromatin activity on the human CYP24 promoter. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY 89-90: 277-279. 2004

Frank C, Macias Gonzalez M, Oinonen C, Dunlop TW, Carlberg C. 2003. Characterization of DNA complexes formed by the nuclear receptor constitutive androstane receptor JOURNAL OF BIOLOGICAL CHEMISTRY 278 44: 43299-43310. 2003

Väisänen S, Peräkylä M, Kärkkäinen JI, Uskokovic MR, Carlberg C. 2003. Structural evaluation of the agonistic action of a vitamin D analog with two side chains binding to the nuclear vitamin D receptor. MOLECULAR PHARMACOLOGY 63 6: 1230-1237. 2003

Macias Gonzalez M, Samenfeld P, Peräkylä M, Carlberg C. 2003. Corepressor excess shifts the two-side chain vitamin D analog gemini from an agonist to an inverse agonist of the vitamin D receptor. MOLECULAR ENDOCRINOLOGY 17 10: 2028-2038. 2003

Carlberg C, Mourino A. 2003. New vitamin D receptor ligands EXPERT OPINION ON THERAPEUTIC PATENTS 13 6: 761-772. 2003

Carlberg C. 2003. Molecular basis of the selective activity of vitamin D analogues. JOURNAL OF CELLULAR BIOCHEMISTRY 88: 274-281. 2003

Carlberg C. 2003. Current understanding of the function of the nuclear vitamin D receptor in response to its natural and synthetic ligands: J Reichrath, M Friedrich, W Tilgen, Vitamin D Analogs in Cancer Prevention and Therapy.Springer-Verlag. Recent Results in Cancer Research. 29-42. 2003

Andersin T, Väisänen S, Carlberg C. 2003. The critical role of carboxy-terminal amino acids in ligand-dependent and -independent transactivation of the constitutive androstane receptor MOLECULAR ENDOCRINOLOGY 17 2: 234-246. 2003

Macias Gonzalez M, Carlberg C. 2002. Cross-repression, a functional consequence of the physical interaction of non-liganded nuclear receptors and POU domain transcription factors. JOURNAL OF BIOLOGICAL CHEMISTRY 277 21: 18501-18509. 2002

Mäkinen J, Frank C, Jyrkkärinne J, Gynther J, Carlberg C, Honkakoski P. 2002. Modulation of mouse and human phenobarbital-responsive enhancer module by nuclear receptors. MOLECULAR PHARMACOLOGY 62 2: 366-378. 2002

Quack M, Frank C, Carlberg C. 2002. Differential nuclear receptor signalling from DR4-type response elements. JOURNAL OF CELLULAR BIOCHEMISTRY 86: 601-612. 2002

Toell A, Kröncke K-D, Kleinert H, Carlberg C. 2002. Orphan nuclear receptor binding site in the human inducible nitric oxide synthase promoter mediates responsiveness to steroid and xenobiotic ligands. JOURNAL OF CELLULAR BIOCHEMISTRY 85: 72-82. 2002

Väisänen S, Peräkylä M, Kärkkäinen JI, Steinmeyer A, Carlberg C. 2002. Critical role of helix 12 of the vitamin D3 receptor for the partial agonism of carboxylic ester antagonists. JOURNAL OF MOLECULAR BIOLOGY 315: 229-238. 2002

Lampen A, Carlberg C, Nau H. 2001. Peroxisome proliferator-activated receptor delta is a specific sensor for teratogenic valproic acid derivatives. EUROPEAN JOURNAL OF PHARMACOLOGY 431: 25-33. 2001

Mork Hansen C , Binderup L, Hamberg KJ, Carlberg C. 2001. Vitamin D and cancer: Effects of 1,25(OH)2D3 and its analogs on growth control and tumorigenesis. FRONTIERS IN BIOSCIENCE 6: d820-d848. 2001

Quack M, Carlberg C. 2001. Single thyroid hormone receptor monomers are competent for co-activator-mediated transactivation. BIOCHEMICAL JOURNAL 360: 387-393. 2001

Toell A, Macias Gonzalez M, Ruf D, Steinmeyer A, Ishizuka S, Carlberg C. 2001. Different molecular mechanisms of vitamin D3 receptor antagonists MOLECULAR PHARMACOLOGY 59 6: 1478-1485. 2001

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