Carsten Carlberg
Professori
Professor of Biochemistry
Biolääketieteen yksikkö, Lääketieteen laitos, Terveystieteiden tiedekunta
carsten.carlberg@uef.fi | 040 355 3062
The research of Carsten Carlberg is directed to gene regulation and epigenetics by vitamin D.
Over 245 of his publications are listed in the Science Citation Index. These have been cited more than 11,000 times leading to h-index of 58 (Web of Science/Publons). So far he finished the supervision of 13 post-doctoral fellows, 19 doctoral students (18 PhD, 1 MD) and 32 MSc students.
Carsten Carlberg published textbooks on ”Mechanisms of Gene Regulation”, ”Nutrigenomics”, ”Human Epigenomics” and ”Cancer Biology”.
Avainsanat
Julkaisut
196/196 kappaletta-
Vitamin D and Aging: Central Role of Immunocompetence
Carlberg, Carsten; Velleuer, Eunike. 2024. Nutrients. 16: -
Concepts of multi-level dynamical modelling: understanding mechanisms of squamous cell carcinoma development in Fanconi anemia
Velleuer, Eunike; Domínguez-Hüttinger, Elisa; Rodríguez, Alfredo; Harris, Leonard A; Carlberg, Carsten. 2023. Frontiers in genetics. 14: . 1254966 -
Epigenetik des Menschen
Carlberg, Carsten; Molnár, Ferdinand. 2023. . . Springer Spektrum -
Genomic signaling of vitamin D
Carlberg, Carsten. 2023. Steroids. 198: . 109271 -
In Vivo Regulation of Signal Transduction Pathways by Vitamin D Stabilizes Homeostasis of Human Immune Cells and Counteracts Molecular Stress
Jaroslawska, Julia; Carlberg, Carsten. 2023. International journal of molecular sciences. 24: -
Intervention Approaches in Studying the Response to Vitamin D3 Supplementation
Gospodarska, Emilia; Ghosh Dastidar, Ranjini; Carlberg, Carsten. 2023. Nutrients. 15: -
Linking Mechanisms of Vitamin D Signaling with Multiple Sclerosis
Carlberg, Carsten; Mycko, Marcin P. 2023. Cells. 12: . 2391 -
Molecular Medicine : How Science Works
Carlberg, Carsten; Velleuer, Eunike; Molnár, Ferdinand. 2023. . . Springer -
Nursing students’ genomics literacy: Basis for genomics nursing education course development
Parviainen, Anndra; Ward, Linda D; Halkoaho, Arja; Laing, Bobbi; Maguire, Jane; Palovaara, Marjo; Mandysova, Petra; Bacungan, Gabriel; Mamungay, Jima J; Sund, Reijo; Mikkonen, Santtu; Carlberg, Carsten; Vehviläinen-Julkunen, Katri. 2023. Teaching and learning in nursing. 18: 6-11 -
Nutrigenomics and redox regulation: Concepts relating to the Special Issue on nutrigenomics
Klotz, Lars-Oliver; Carlberg, Carsten. 2023. Redox biology. 68: -
Nutrigenomics in the context of evolution
Carlberg, Carsten. 2023. Redox biology. 62: -
Vitamin D, chromatin, and epigenetics
Carlberg, Carsten. Teoksessa: Hewison, Martin; Bouillon, Roger; Giovannucci, Edward; Goltzman, David; Meyer, Mark; Welsh, JoEllen(toim.) , 2023. Feldman and Pike's Vitamin D: Volume One: Biochemistry, Physiology and Diagnostics. s. 229-239. Academic press -
Vitamin D: A master example of nutrigenomics
Carlberg, Carsten; Raczyk, Marianna; Zawrotna, Natalia. 2023. Redox biology. 62: . 102695 -
A Pleiotropic Nuclear Hormone Labelled Hundred Years Ago Vitamin D
Carlberg, Carsten. 2022. Nutrients. 2023; 15: -
A Single Oral Vitamin D3 Bolus Reduces Inflammatory Markers in Healthy Saudi Males
AlGhamdi, Shareefa A.; Enaibsi, Nusaibah N.; Alsufiani, Hadeil M.; Alshaibi, Huda F.; Khoja, Sawsan O.; Carlberg, Carsten. 2022. International journal of molecular sciences. 23: -
A Single Vitamin D3 Bolus Supplementation Improves Vitamin D Status and Reduces Proinflammatory Cytokines in Healthy Females
Alsufiani, Hadeil M.; AlGhamdi, Shareefa A.; AlShaibi, Huda F.; Khoja, Sawsan O.; Saif, Safa F.; Carlberg, Carsten. 2022. Nutrients. 14: -
An update on vitamin D signaling and cancer
Carlberg, Carsten; Muñoz, Alberto. 2022. Seminars in cancer biology. 79: 217-230 -
Gene-Regulatory Potential of 25-Hydroxyvitamin D3 and D2
Hanel, Andrea; Veldhuizen, Cor; Carlberg, Carsten. 2022. Frontiers in nutrition. 9: . 910601 -
Linguistic Validation of Genomic Nursing Concept Inventory to Finnish Applying Mandysova’s Decision Tree Algorithm
Dumo, Anndra Margareth; Mandysova, Petra; Ward, Linda D.; Laing, Bobbi; Lim, Anecita Gigi; Palovaara, Marjo; Saunders, Hannele; Maguire, Jane; Carlberg, Carsten; Sund, Reijo; Vehviläinen-Julkunen, Katri. 2022. Journal of nursing measurement. 31: 1-18 -
Molecular Immunology: How Science Works
Carlberg, Carsten; Velleuer, Eunike. 2022. . . Springer -
Nutrigenomik : Gene und unsere Ernährung
Carlberg, Carsten; Klotz, Lars-Oliver; Molnár, Ferdinand. 2022. . . Springer -
Nutrition and epigenetic programming
Carlberg, Carsten; Velleuer, Eunike. 2022. Current opinion in clinical nutrition and metabolic care. [December 26, 2022, Publish Ahead of Print]: 1-7 -
Time-Resolved Gene Expression Analysis Monitors the Regulation of Inflammatory Mediators and Attenuation of Adaptive Immune Response by Vitamin D
Hanel, Andrea; Carlberg, Carsten. 2022. International journal of molecular sciences. 23: -
Vitamin D and Its Target Genes
Carlberg, Carsten. 2022. Nutrients. 14: -
Vitamin D and Pigmented Skin
Carlberg, Carsten. 2022. Nutrients. 14: -
Vitamin D and the risk for cancer: A molecular analysis
Carlberg, Carsten; Velleuer, Eunike. 2022. Biochemical pharmacology. 196: -
Vitamin D in the Context of Evolution
Carlberg, Carsten. 2022. Nutrients. 14: -
A hierarchical regulatory network analysis of the vitamin D induced transcriptome reveals novel regulators and complete VDR dependency in monocytes
Warwick, Timothy; Schulz, Marcel H; Guenther, Stefan; Gilsbach, Ralf; Neme, Antonio; Carlberg, Carsten; Brandes, Ralf P; Seuter, Sabine. 2021. Scientific reports. 11: 6518 -
Cancer Biology: How Science Works
Carlberg, Carsten; Velleuver, Eunike. 2021. . . Springer Nature -
Replacing Saturated Fat with Polyunsaturated Fat Modulates Peripheral Blood Mononuclear Cell Gene Expression and Pathways Related to Cardiovascular Disease Risk Using a Whole Transcriptome Approach
Larsen, Sunniva, V; Holven, Kirsten B; Christensen, Jacob J; Flatberg, Arnar; Rundblad, Amanda; Leder, Lena; Blomhoff, Rune; Telle-Hansen, Vibeke; Kolehmainen, Marjukka; Carlberg, Carsten; Myhrstad, Mari C; Thoresen, Magne; Ulven, Stine M. 2021. Molecular nutrition and food research. 65: 2100633 -
Transcriptome-Wide Profile of 25-Hydroxyvitamin D3 in Primary Immune Cells from Human Peripheral Blood
Hanel, Andrea; Bendik, Igor; Carlberg, Carsten. 2021. Nutrients. 13: 4100 -
Vitamin D Treatment Sequence Is Critical for Transcriptome Modulation of Immune Challenged Primary Human Cells
Malmberg, Henna-Riikka; Hanel, Andrea; Taipale, Mari; Heikkinen, Sami; Carlberg, Carsten. 2021. Frontiers in immunology. 12: 754056 -
Common and personal target genes of the micronutrient vitamin D in primary immune cells from human peripheral blood
Hanel, Andrea; Neme, Antonio; Malinen, Marjo; Hämäläinen, Emmi; Malmberg, Henna-Riikka; Etheve, Stéphane; Tuomainen, Tomi-Pekka; Virtanen, Jyrki K; Bendik, Igor; Carlberg, Carsten. 2020. Scientific reports. 10: 21051 -
Genome-wide effects of chromatin on vitamin D signaling
Hanel, Andrea; Malmberg, Henna-Riikka; Carlberg, Carsten. 2020. Journal of molecular endocrinology. 64: R45-R56 -
Impact of Epigenetics on Complications of Fanconi Anemia: The Role of Vitamin D-Modulated Immunity
Velleuer, Eunike; Carlberg, Carsten. 2020. Nutrients. 12: 1355 -
Key Vitamin D Target Genes With Functions in the Immune System
Koivisto, Oona; Hanel, Andrea; Carlberg, Carsten. 2020. Nutrients. 12: 1140 -
Mechanisms of Gene Regulation: How Science works
Carlberg, Carsten; Molnár, Ferdinand. 2020. . . Springer Nature -
Monitoring genome-wide chromatin accessibility by formaldehyde-assisted isolation of regulatory elements sequencing (FAIRE-seq)
Seuter, Sabine; Neme, Antonio; Carlberg, Carsten. Teoksessa: Tollefsbol, Trygve(toim.) , 2020. Epigenetics Methods. s. 353-369. Elsevier -
Nutrigenomics: How Science works
Carlberg, Carsten; Ulven, Stine Marie; Molnár, Ferdinand. 2020. . . Springer -
Randomized controlled trial on the effectiveness of web-based Genomics Nursing Education Intervention for undergraduate nursing students: a study protocol
Dumo, AM; Laing, B; Lim, AG; Palaganas, E; Abad, PJ; Valdehueza, O; Palovaara, M; Saunders, H; Estola, M; Mandysova, P; Maguire, J; Ward, LD; Carlberg, C; Vehviläinen-Julkunen, K. 2020. Journal of advanced nursing. 76: 3136-3146 -
Skin Color and Vitamin D: An Update
Hanel, Andrea; Carlberg, Carsten. 2020. Experimental dermatology. 29: 864-875 -
Vitamin D and evolution: pharmacologic implications
Hanel, Andrea; Carlberg, Carsten. 2020. Biochemical pharmacology. 173: 113595 -
Vitamin D receptor(s): in the nucleus but also at membranes?
Zmijewski, MA; Carlberg, C. 2020. Experimental dermatology. 29: 876-884 -
An Isocaloric Nordic Diet Modulates RELA and TNFRSF1A Gene Expression in Peripheral Blood Mononuclear Cells in Individuals with Metabolic Syndrome-A SYSDIET Sub-Study
Ulven, SM; Holven, KB; Rundblad, A; Myhrstad, MCW; Leder, L; Dahlman, I; Mello, VD; Schwab, U; Carlberg, C; Pihlajamäki, J; Hermansen, K; Dragsted, LO; Gunnarsdottir, I; Cloetens, L; Åkesson, B; Rosqvist, F; Hukkanen, J; Herzig, KH; Savolainen, MJ; Risérus, U; et al. [incl. Uusitupa, M]. 2019. Nutrients. 11: 2932 -
Healthy Nordic Diet Modulates the Expression of Genes Related to Mitochondrial Function and Immune Response in Peripheral Blood Mononuclear Cells from Subjects with the Metabolic Syndrome - A SYSDIET Sub-Study
Myhrstad, MC; de Mello, VD; Dahlman, I; Kolehmainen, M; Paananen, J; Rundblad, A; Carlberg, C; Olstad, OK; Pihlajamäki, J; Holven, KB; Hermansen, K; Dragsted, LO; Gunnarsdottir, I; Cloetens, L; Storm, MU; Åkesson, B; Rosqvist, F; Hukkanen, J; et al. (incl. Schwab, U; Uusitupa, M). 2019. Molecular nutrition and food research. 63: 1801405 -
Highlights from the 21st Workshop on Vitamin D in Barcelona, May 2018
Fleet, JC; Campbell, MJ; Carlberg, C; Demay, MB; Ebeling, PR; Schoenmakers, I; White, JH; Welsh, J; Hewison, M. 2019. Journal of steroid biochemistry and molecular biology. 189: 210-217 -
In vivo transcriptome changes of human white blood cells in response to vitamin D
Neme, Antonio; Seuter, Sabine; Malinen, Marjo; Nurmi, Tarja; Tuomainen, Tomi-Pekka; Virtanen, Jyrki K; Carlberg, Carsten. 2019. Journal of steroid biochemistry and molecular biology. 188: 71-76 -
Nutrigenomics of Vitamin D
Carlberg, Carsten. 2019. Nutrients. 11: 676 -
Primary Vitamin D Target Genes of Human Monocytes
Nurminen, V; Seuter, S; Carlberg, C. 2019. Frontiers in physiology. 10: 194 -
Vitamin D Signaling Suppresses Early Prostate Carcinogenesis in TgAPT121 Mice
Fleet, JC; Kovalenko, PL; Li, Y; Smolinski, J; Spees, C; Yu, JG; Thomas-Ahner, JM; Cui, M; Neme, A; Carlberg, C; Clinton, SK. 2019. Cancer prevention research. 12: 343-356 -
Vitamin D Signaling in the Context of Innate Immunity: Focus on Human Monocytes
Carlberg, Carsten. 2019. Frontiers in immunology. 10: 2211 -
Vitamin D and Its Synthetic Analogs
Maestro, Miguel A; Molnár, Ferdinand; Carlberg, Carsten. 2019. Journal of medicinal chemistry. 62: 6854-6875 -
Vitamin D: A Micronutrient Regulating Genes
Carlberg, Carsten. 2019. Current pharmaceutical design. 25: 1740-1746 -
A Machine learning approaches infer vitamin D signaling: Critical impact of vitamin D receptor binding within topologically associated domains
Carlberg, Carsten; Neme, Antonio. 2018. Journal of steroid biochemistry and molecular biology. 2019; 15: 103-109 -
ETS transcription factor family member GABPA contributes to vitamin D receptor target gene regulation
Seuter, Sabine; Neme, Antonie; Carlberg, Carsten. 2018. Journal of steroid biochemistry and molecular biology. 177: 46-52 -
Highlights from the 6th International Conference on Vitamin D Deficiency, "Nutrition and Human Health", Abu Dhabi, United Arab Emirates, March 9-10, 2017
Haq, Afrozul; Wimalawansa, Sunil J; Carlberg, Carsten. 2018. Journal of steroid biochemistry and molecular biology. 180: 1-3 -
Human Epigenomics
Carlberg, Carsten; Molnár, Ferdinand. 2018. . . Springer -
In vivo response of the human epigenome to vitamin D: A proof-of-principle study
Carlberg, Carsten; Seuter, Sabine; Nurmi, Tarja; Tuomainen, Tomi-Pekka; Virtanen, Jyrki K; Neme, Antonio. 2018. Journal of steroid biochemistry and molecular biology. 180: 142-148 -
Modulation of vitamin D signaling by the pioneer factor CEBPA
Nurminen, Veijo; Neme, Antonio; Seuter, Sabine; Carlberg, Carsten. 2018. Biochimica et biophysica acta: gene regulatory mechanisms. 2019; 1862: 96-106 -
The impact of the vitamin D-modulated epigenome on VDR target gene regulation
Nurminen, Veijo; Neme, Antonio; Seuter, Sabine; Carlberg, Carsten. 2018. Biochimica et biophysica acta: gene regulatory mechanisms. 1861: 697-705 -
Vitamin D
Carlberg, Carsten. Teoksessa: Maccarrone, Mauro; Clarke, Angus; Zheng, Yixian; Tickle, Cheryll; Kehrer-Sawatzki, Hildegard; Cooper, David N; Delves, Peter; Pettis, Gregg; Candi, Eleonora; Perkel, David J; Hetherington, Alistair M; Bynum, William F; Valpuesta, José María; Harper, David(toim.) , 2018. Encyclopedia of Life Sciences (eLS). s. -. John Wiley & Sons -
Vitamin D Genomics: From In Vitro to In Vivo
Carlberg, Carsten. 2018. Frontiers in endocrinology. 9: 250 -
Endocrine functions of vitamin D
Carlberg Carsten. 2017. Molecular and cellular endocrinology. 453: 1-2 -
Epigenomic PU.1-VDR crosstalk modulates vitamin D signaling
Seuter S, Neme A, Carlberg C. 2017. Biochimica et biophysica acta: gene regulatory mechanisms. 1860: 405-415 -
Highlights from the 5th International Conference on Vitamin D Deficiency, Nutrition and Human Health, Abu Dhabi, United Arab Emirates, March 24-25, 2016
Haq A, Wimalawansa SJ, Carlberg C. 2017. Journal of steroid biochemistry and molecular biology. 175: 1-3 -
Integration of VDR genome wide binding and GWAS genetic variation data reveals co-occurrence of VDR and NF-kappaB binding that is linked to immune phenotypes
Singh PK, van den Berg PR, Long MD, Vreugdenhil A, Grieshober L, Ochs-Balcom HM, Wang J, Delcambre S, Heikkinen S, Carlberg C, Campbell MJ, Sucheston-Campbell LE. 2017. Bmc genomics. 18: - -
Molecular endocrinology of vitamin D on the epigenome level
Carlberg Carsten. 2017. Molecular and cellular endocrinology. 453: 14-21 -
Molecular evaluation of vitamin D responsiveness of healthy young adults
Seuter Sabine, Virtanen Jyrki K, Nurmi Tarja, Pihlajamäki Jussi, Mursu Jaakko, Voutilainen Sari, Tuomainen Tomi-Pekka, Neme Antonio, Carlberg Carsten. 2017. Journal of steroid biochemistry and molecular biology. 174: 314-321 -
Selective regulation of biological processes by vitamin D based on the spatio-temporal cistrome of its receptor
Neme Antonio, Seuter Sabine, Carlberg Carsten. 2017. Biochimica et biophysica acta: gene regulatory mechanisms. 1860: 952-961 -
The concept of the personal vitamin D response index
Carlberg Carsten, Haq Afrozul. 2017. Journal of steroid biochemistry and molecular biology. 2018; 175: 12-17 -
Vitamin D and chromatin
Carlberg Carsten. Teoksessa: Feldman David, Pike J Wesley, Bouillon Roger, Giovannucci Edward, Goltzman David, Hewison Martin(toim.) , 2017. Vitamin D. 4th Edition. Volume 1: Biochemistry, Physiology and Diagnostics. s. 217-226. Elsevier -
Effects of a healthy Nordic diet on gene expression changes in peripheral blood mononuclear cells in response to an oral glucose tolerance test in subjects with metabolic syndrome: a SYSDIET sub-study
Leder Lena, Kolehmainen Marjukka, Narverud Ingunn, Dahlman Ingrid, Myhrstad Mari CW, de Mello Vanessa D, Paananen Jussi, Carlberg Castren, Schwab Ursula, Herzig Karl-Heinz, Cloetens Lieselotte, Storm Matilda Ulmius, Hukkanen Janne, Savolainen Markku J, Rosqvist Fredrik, Hermansen Kjeld, Dragsted Lars O, Gunnarsdottir Ingibjörk, Thorsdottir Inga, Risérus Ulf et al.. 2016. Genes and nutrition. 11: 1-13 -
Mechanisms of gene regulation (2. ed)
Carlberg Carsten, Molnár Ferdinand. 2016. . 2nd ed. Springer -
Nutrigenomics
Carlberg Carsten, Ulven Stine Marie, Molnár Ferdinand. 2016. . . Springer -
Vitamin D
Carlberg Carsten. Teoksessa: Caplan Michael(toim.) , 2016. Reference Module in Biomedical Sciences. s. -. Elsevier -
Vitamin D receptor 2016: novel ligands and structural insights
Maestro Miguel A, Molnár Ferdinand, Mouriño Antonio, Carlberg Carsten. 2016. Expert opinion on therapeutic patents. 26: 1291-1306 -
Vitamin D receptor signaling improves Hutchinson-Gilford progeria syndrome cellular phenotypes
Kreienkamp Ray, Croke Monica, Neumann Martin A, Bedia-Diaz Gonzalo, Graziano Simona, Dusso Adriana, Dorsett Dale, Carlberg Carsten, Gonzalo Susana. 2016. Oncotarget. 7: 30018-30031 -
Vitamin D-dependent chromatin association of CTCF in human monocytes
Neme Antonio, Seuter Sabine, Carlberg Carsten. 2016. Biochimica et biophysica acta: gene regulatory mechanisms. 1859: 1380-1388 -
Epigenome-wide effects of vitamin D and their impact on the transcriptome of human monocytes involve CTCF
Seuter Sabine, Neme Antonio, Carlberg Carsten. 2015. Nucleic acids research. 2016; 44: 4090-4104 -
Molecular approaches for optimizing vitamin D supplementation
Carlberg Carsten. 2015. Vitamins and hormones series. 2016; 100: 255-271 -
Multiplex Eukaryotic Transcription (In) activation: Timing, Bursting and Cycling of a Ratchet Clock Mechanism
Rybakova Katja N, Bruggeman Frank J, Tomaszewska Aleksandra, Moné Martijn J, Carlberg Carsten, Westerfoff Hans V. 2015. PLoS computational biology. 11: e1004236 -
Relevance of Vitamin D Receptor Target Genes for Monitoring the Vitamin D Responsiveness of Primary Human Cells
Vukic Maja, Neme Antonio, Seuter Sabine, Saksa Noora, de Mello Vanessa DF, Nurmi Tarja, Uusitupa Matti, Tuomainen Tomi-Pekka, Virtanen Jyrki K, Carlberg Carsten. 2015. PLoS ONE. 10: e0124339 -
The vitamin D-dependent transcriptome of human monocytes
Neme Antonio, Nurminen Veijo, Seuter Sabine, Carlberg Carsten. 2015. Journal of steroid biochemistry and molecular biology. 2016; 164: 180-187 -
Vitamin D receptor signaling and its therapeutic implications: Genome-wide and structural view
Carlberg Carsten, Molnár Ferdinand. 2015. Canadian journal of physiology and pharmacology. 93: 311-318 -
Changes in vitamin D target gene expression in adipose tissue monitor the vitamin D response of human individuals
Ryynänen Jussi, Neme Antonio, Tuomainen Tomi-Pekka, Virtanen Jyrki K, Voutilainen Sari, Nurmi Tarja, de Mello Vanessa DF, Uusitupa Matti, Carlberg Carsten. 2014. Molecular nutrition and food research. 58: 2036-2045 -
Characterization of genomic vitamin D receptor binding sites through chromatin looping and opening
Seuter Sabine, Neme Antonio, Carlberg Carsten. 2014. PLoS ONE. 9: e96184 -
Dissecting high from low responders in a vitamin D3 intervention study
Saksa Noora, Neme Antonio, Ryynänen Jussi, Uusitupa Matti, de Mello Vanessa DF, Voutilainen Sari, Nurmi Tarja, Virtanen Jyrki K, Tuomainen Tomi-Pekka, Carlberg Carsten. 2014. Journal of steroid biochemistry and molecular biology. Epub ahead of print: - -
Effects of a healthy Nordic diet on plasma 25-hydroxyvitamin D concentration in subjects with metabolic syndrome: a randomized, placebo-controlled trial (SYSDIET)
Brader Lea, Rejnmark Lars, Carlberg Carsten, Schwab Ursula, Kolehmainen Marjukka, Rosqvist Fredrik, Cloetens Lieselotte, Landin-Olsson Mona, Gunnarsdottir Ingibjorg, Poutanen Kaisa S, Herzig Karl-Heinz, Risérus Ulf, Savolainen Markku J, Thorsdottir Inga, Uusitupa Matti, Hermansen Kjeld. 2014. European journal of nutrition. 53: 1123-34 -
From pharmacogenomics to integrated personal omics profiling: a gap in implementation into healthcare
Carlberg Carsten, Raunio Hannu. 2014. Personalized medicine. 11: 625-629 -
Genome-wide (over)view on the actions of vitamin D
Carlberg Carsten. 2014. Frontiers in physiology. 5: 1-10 -
Healthy Nordic diet downregulates the expression of genes involved in inflammation in subcutaneous adipose tissue in individuals with features of the metabolic syndrome
Kolehmainen Marjukka, Ulven Stine M, Paananen Jussi, de Mello Vanessa, Schwab Ursula, Carlberg Carsten, Myhrstad Mari, Pihlajamäki Jussi, Dungner Elisabeth, Sjölin Eva, Gunnarsdottir Ingibjörg, Cloetens Lieselotte, Landin-Olsson Mona, Akesson Björn, Rosqvist Fredrik, Hukkanen Janne, Herzig Karl-Heinz, Dragsted Lars O, Savolainen Markku J, Brader Lea, Hermansen Kjeld, Risérus Ulf, Thorsdottir Inga, Poutanen Kaisa S, Uusitupa Matti, Arner Peter, Dahlman Ingrid. 2014. American journal of clinical nutrition. 101: 228-239 -
Mechanisms of Gene Regulation
Carlberg Carsten, Molnár Ferdinand. 2014. . . Springer -
Patterns of Genome-Wide VDR Locations
Tuoresmäki Pauli, Väisänen Sami, Neme Antonio, Heikkinen Sami, Carlberg Carsten. 2014. PLoS ONE. 9: e96105 -
Primary vitamin D receptor target genes as biomarkers for the vitamin D3 status in the hematopoietic system
Wilfinger Julia, Seuter Sabine, Tuomainen Tomi-Pekka, Virtanen Jyrki K, Voutilainen Sari, Nurmi Tarja, de Mello Vanessa DF, Uusitupa Matti, Carlberg Carsten. 2014. Journal of nutritional biochemistry. 25: 875-884 -
The physiology of vitamin D - far more than calcium and bone
Carlberg Carsten. 2014. Frontiers in physiology. 5: - -
The transcriptional regulator BCL6 participates in the secondary gene regulatory response to vitamin D
Nurminen Veijo, Neme Antonio, Ryynänen Jussi, Heikkinen Sami, Seuter Sabine, Carlberg Carsten. 2014. Biochimica et biophysica acta: gene regulatory mechanisms. Epub ahead of print: - -
Tracing the molecular basis of transcriptional dynamics in noisy data by using an experiment-based mathematical model
Rybakova Katja N, Tomaszewska Aleksandra, van Mourik Simon, Blom Joke, Westerhoff Hans V, Carlberg Carsten, Bruggeman Frank J. 2014. Nucleic acids research. Epub ahead of print: - -
What Do We Learn from the Genome-wide Perspective on Vitamin D3?
Carlberg Carsten. 2014. Anticancer research. 48: 217-218 -
Dynamics of 1α ,25-dihydroxyvitamin D3-dependent chromatin accessibility of early vitamin D receptor target genes
Seuter S, Pehkonen P, Heikkinen S, Carlberg C. 2013. Biochimica et biophysica acta: international journal of biochemistry and biophysics. 1829: 1266-1275 -
Gene Regulatory Scenarios of Primary 1,25-Dihydroxyvitamin D3 Target Genes in a Human Myeloid Leukemia Cell Line
Ryynänen J, Seuter S, Campbell MJ, Carlberg C. 2013. Cancers. 5: 1221-1241 -
Primary 1,25-Dihydroxyvitamin D3 Response of the Interleukin 8 Gene Cluster in Human Monocyte- and Macrophage-Like Cells
Ryynänen J, Carlberg C. 2013. PLoS ONE. 8: e78170 -
Primary vitamin D target genes allow a categorization of possible benefits of vitamin D3 supplementation
Carlberg C, Seuter S, de Mello VDF, Schwab U, Voutilainen S, Pulkki K, Nurmi T, Virtanen J, Tuomainen T-P, Uusitupa M. 2013. PLoS ONE. 8: e71042 -
The ASAP2 gene is a primary target of 1,25-dihydroxyvitamin D3 in human monocytes and macrophages
Seuter S, Ryynänen J, Carlberg C. 2013. Journal of steroid biochemistry and molecular biology. [Epub ahead of print]: x-x -
Vitamin D receptor signaling mechanisms: Integrated actions of a well-defined transcription factor
Carlberg C, Campbell MJ. 2013. Steroids. 78: 127-136 -
Chromatin acetylation at transcription start sites and vitamin D receptor binding regions relates to effects of 1alfa,25-dihydroxyvitamin D3 and histone deacetylase inhibitors on gene expression
Seuter S, Heikkinen S, Carlberg C. 2012. Nucleic acids research. -: - -
Current status of vitamin D signaling and its therapeutic applications
Carlberg Carsten, Molnár Ferdinand. 2012. Current topics in medicinal chemistry. 12: 528-547 -
Dataset integration identifies transcriptional regulation of microRNA genes by PPARgamma in differentiating mouse 3T3-L1 adipocytes
John E, Wienecke-Baldacchino A, Liivrand M, Heinäniemi M, Carlberg C, Sinkkonen L. 2012. Nucleic acids research. 40: 4446-4460 -
Differential effects of 1alfa,25-dihydroxycholecalciferol on MCP-1 and adiponectin production in human white adipocytes
Lorente-Cebrián S, Eriksson A, Dunlop T, Mejhert N, Dahlman I, Åström G, Sjölin E, Wåhlén K, Carlberg C, Laurencikiene J, Hedén P, Arner P, Rydén M. 2012. European journal of nutrition. 51: 335-342 -
Genome-wide landscape of liver X receptor chromatin binding and gene regulation in human macrophages
Pehkonen P, Welter-Stahl L, Diwo J, Ryynänen J, Wienecke-Baldacchino A, Heikkinen S, Treuter E, Steffensen K, Carlberg C. 2012. Bmc genomics. 13: - -
Inhibition of cytokine secretion from adipocytes by 1,25-dihydroxyvitamin D3 via the NF-kappaB pathway
Mutt SJ, Karhu T, Lehtonen S, Lehenkari P, Carlberg C, Saarnio J, Sebert S, Hyppönen E, Järvelin M-R, Herzig K-H. 2012. Faseb journal. 26: 4400-4407 -
The First Genome-wide View of Vitamin D Receptor Locations and Their Mechanistic Implications
Carlberg C, Seuter S, Heikkinen S. 2012. Anticancer research. 32: 271-282 -
The gene for the transcription factor BHLHE40/DEC1/stra13 is a dynamically regulated primary target of the vitamin D receptor
Seuter S, Pehkonen P, Heikkinen S, Carlberg C. 2012. Journal of steroid biochemistry and molecular biology. online: - -
The need for education in personalized medicine
Carlberg C. 2012. Personalized medicine. 9: 147-150 -
Vitamin D receptor ligands: the impact of crystal structures
Carlberg Carsten, Molnár Ferdinand, Mouriño Antonio. 2012. Expert opinion on therapeutic patents. 22: 417-435 -
1,25-Dihydroxyvitamin D(3) Influences Cellular Homocystine Levels in Murine Preosteoplastic MC3T3-E1 Cells by Directs Regulation of Cystathionine beta-Synthase
Kriebitzsch C, Verlinden L, Eelen G, van Schoor NM, Swart K, Lips P, Meyer MB, Pike JW, Boonen S, Carlberg C, Vitvitsky V, Bouillon R, Banerjee R, Verstuyf A. 2011. Journal of bone and mineral research. 26: 2991-2000 -
Cyclical regulation of the insulin-like growth factor binding protein 3 gene in response to 1alpha,25-dihydroxyvitamin D3
Malinen Marjo, Ryynänen Jussi, Heinniemi Merja, Sami Väisänen Sami, Carlberg Carsten. 2011. Nucleic acids research. 39: 502-512 -
Dynamic nature of transcriptional regulation of nuclear receptor target genes in the context of chromatin organization
Väisänen Sami, Matilainen Juha, Carlberg Carsten. 2011. Dermato-endocrinology. 3: 1-5 -
Electrophilic nitro-fatty acids activate NRF2 by a KEAP1 cysteine 151-independent mechanism
Kansanen Emilia, Bonacci Gustavo, Schopfer Francisco J, Kuosmanen Suvi M, Tong Kit I, Leinonen Hanna, Woodcock Steven R, Yamamoto Masayuk, Carlberg Carsten, Ylä-Herttuala Seppo, Freeman Bruce A, Levonen Anna-Liisa. 2011. Journal of biological chemistry. 286: 14019-14027 -
Mechanism of 1α ,25-dihydroxyvitamin D3-dependent repression of interleukin-12B
Gynther Petra, Toropainen Sari, Matilainen Juha M, Seuter Sabine, Carlberg Carsten, Väisänen Sami. 2011. Biochimica et biophysica acta: molecular cell research. 1813: 810-818 -
Nuclear hormone 1α ,25-dihydroxyvitamin D3 elicits a genome-wide shift in the locations of VDR chromatin occupancy
Heikkinen Sami, Väisänen Sami, Pehkonen Petri, Seuter Sabine, Benes Vladimir, Carlberg Carsten. 2011. Nucleic acids research. 39: 9181-9193 -
Target genes of vitamin D: Spatio-temporal interaction of chromatin, VDR and response elements
Carlberg Carsten. Teoksessa: Feldman David, Pike J. Wesley, Adams John S.(toim.) , 2011. Vitamin D, Third Edition. s. 211-226. Academic press -
25-Hydroxyvitamin D3 is an Agonistic Vitamin D Receptor Ligand
Lou, Y-R., Molnár, F., Peräkylä, M., Qiao, S., Kalueff, A.V., St-Arnaud, R., Carlberg, C. and Tuohimaa, P.. 2010. Journal of steroid biochemistry and molecular biology. 118: 162-170 -
Design principles of nuclear receptor signaling: how complex networking improves signal transduction
Kolodkin AN, Frank J, Bruggeman FJ, Plant N, Moné MJ, Bakker B, Campbell MJ, van Leeuwen JPTM, Carlberg C, Snoep JL, Westerhoff HV. 2010. Molecular systems biology. 6: - -
Diversity of vitamin D target genes
Carlberg Carsten. Teoksessa: Holick MF (ed)(toim.) , 2010. Nutrition and Health: Vitamin D, 2nd Edition. s. 255-274. Humana Press -
Dynamics of nuclear receptor target gene regulation
Carlberg Carsten, Seuter Sabine. 2010. Chromosoma. 119: 479-484 -
Molecular Mechanism of Allosteric Communication in the human PPAR alpha -RXR alpha Heterodimer
Venäläinen, T., Molnár, F., Oostenbrink, C., Carlberg, C. and Peräkylä M.. 2010. Proteins: structure function and bioinformatics. 78: 873-887 -
New Insights to nuclear receptor gene regulation from analysis of their response elements in target genes
Carlberg Carsten. Teoksessa: Bunce CM, Campbell MJ (editors)(toim.) , 2010. Nuclear Receptors, Proteins and Cell Regulation. s. 419-437. Springer -
Primary effect of 1α ,25(OH)(2)D(3) on IL-10 expression in monocytes is short-term down-regulation
Matilainen JM, Husso T, Toropainen S, Seuter S, Turunen MP, Gynther P, Ylä-Herttuala S, Carlberg C, Väisänen S.. 2010. Biochimica et biophysica acta: molecular cell research. 1803: 1276-1286 -
The Down-regulation of the Human MYC Gene by the Nuclear Hormone 1α ,25-dihydroxyvitamin D3 is Associated with Cycling of Corepressors and Histone Deacetylases
Sari Toropainen, Sami Väisänen, Sami Heikkinen,Carsten Carlberg. 2010. Journal of molecular biology. 400: 284-294 -
The impact of transcriptional cycling on gene regulation
Carlberg Carsten. 2010. Transcription. 1: 13-16 -
The impact of whole genome in silico screening for nuclear receptor binding sites in systems biology
Carlberg, Carsten, Heinäniemi Merja. Teoksessa: Lodhi Huma M, Muggleton Stephen H (editors)(toim.) , 2010. Elements of Computational Systems Biology. s. 309-324. Wiley -
The number of vitamin D receptor binding sites defines the different vitamin D responsiveness of the CYP24 gene in malignant and normal mammary cells.
Matilainen JM, Malinen M, Turunen MM, Carlberg C, Väisänen S. 2010. Journal of biological chemistry. 285: 24174-24183 -
Time-resolved expression profiling of the nuclear receptor superfamily in human adipogenesis
Lahnalampi Mari, Heinäniemi Merja, Sinkkonen Lasse, Wabitsch Martin, Carlberg Carsten. 2010. PLoS ONE. 5: - -
A genomic perspective on vitamin D signaling
Carlberg C, Seuter S. 2009. Anticancer research. 29: 3485-3494 -
Cell cycle regulatory effects of retinoid acid and forskolin are mediated by the Cyclin C gene
Makkonen KM, Malinen M, Ropponen A, Väisänen S, Carlberg C. 2009. Journal of molecular biology. 393: 261-271 -
Cyclical chromatin looping and transcription factor association on the regulatory regions of the p21 (CDKN1A) gene in response to 1[alpha],25-dihydroxyvitamin D3
Saramäki A, Diermeier S, Kellner R, Laitinen H, Väisänen S, Carlberg C. 2009. Journal of biological chemistry. 284: 8073-8082 -
Peroxisome proliferator-activated receptor [alpha] controls hepatic heme biosynthesis throught ALAS1
Degenhardt T, Väisänen S, Rakhshandehroo M, Kersten S, Carlberg C. 2009. Journal of molecular biology. 388: 225-238 -
Population-level transcription cycles derive from stochastic timing of single-cell transcription
Degenhardt T, Rybakova KN, Tomaszewska A, Moné MJ, Westerhoff HV, Bruggeman FJ, Carlberg C. 2009. Cell. 138: 489-501 -
Regulation of the hyaluronan synthase 2 gene by convergence in cyclic AMP response element-binding protein and retinoid acid receptor signaling
Makkonen KM, Pasonen-Seppänen S, Törrönen K, Tammi MI, Carlberg C. 2009. Journal of biological chemistry. 284: 18270-18281 -
A role for the PPARgamma in cancer therapy
Campbell MJ, Carlberg C, Koeffler HP. 2008. Ppar research. : 17 s -
DICKKOPF-4 is induced by TCF/beta-catenin and upregulated in human colon cancer, promotes tumour cell invasion and angiogenesis and is repressed by 1alpha,25-dihydroxyvitamin D3
Pendás-Franco N, García JM, Peña C, Valle N, Pálmer HG, Heinäniemi M, Carlberg C, Jiménez B, Bonilla F, Muñoz A, González-Sancho JM. 2008. Oncogene. 27: 4467-4477 -
Distinct HDACs regulate the transcriptional response of human cyclin-dependent kinase inhibitor genes to trichostatin A and 1alpha,25-dihydroxyvitamin D3
Malinen M, Saramäki A, Ropponen A, Degenhardt T, Väisänen S, Carlberg C. 2008. Nucleic acids research. 36: 121-132 -
Screening for PPAR responsive regulatory modules in cancer
Heinäniemi M, Carlberg C. 2008. Ppar research. 2008: 8 s -
Variations in the ghrelin receptor gene associate with obesity and glucose metabolism in individuals with impaired glucose tolerance
Mager U, Degenhardt T, Pulkkinen L, Kolehmainen M, Tolppanen A-M, Lindström J, Eriksson JG, Carlberg, Tuomilehto J, Uusitupa M, for the Finnish Diabetes Prevention Study Group. 2008. PLoS ONE. 3: e2941 -
Controlling the chromatin organization of vitamin D target genes by multiple vitamin D receptor binding sites
Carlberg C, Dunlop TW, Saramäki A, Sinkkonen L, Matilainen M, Väisänen S. 2007. Journal of steroid biochemistry and molecular biology. : 338-343 -
Functional characterization of vitamin D responding regions in the human 5-lipoxygenase gene
Seuter S, Väisänen S, Rådmark O, Carlberg C, Steinhilber D. 2007. Biochimica et biophysica acta: international journal of biochemistry and biophysics. 1771: 864-872 -
Integration of the activation of the human hyaluronan synthase 2 gene promoter by common cofactors of the transcription factors retinoic acid receptor and nuclear factor kappaB
Saavalainen K, Tammi MI, Bowen T, Lienhard Schmitz M, Carlberg C. 2007. Journal of biological chemistry. 282: 11530-11539 -
Meta-analysis of primary target genes of peroxisome proliferator-activated receptors
Heinäniemi M, Uski JO, Degenhardt T, Carlberg C. 2007. Genome biology. 8: R147 -
Selective use of multiple vitamin D response elements underlies the 1alpha,25-dihydroxyvitamin D3-mediated negative regulation of the human CYP27B1 gene
Turunen MM, Dunlop TW, Carlberg C, Väisänen S. 2007. Nucleic acids research. 35: 2734-2747 -
Subcellular localisation of BAG-1 and its regulation of vitamin D receptor-mediated transactivation and involucrin expression in oral keratinocytes: implications for oral carcinogenesis
Lee SS, Crabb SJ, Janghra N, Carlberg C, Williams AC, Cutress RI, Packham G, Hague A. 2007. Experimental cell research. 313: 3222-3238 -
The vitamin D receptor
Carlberg C, Seuter S. 2007. Dermatologic clinics. 25: 515-523 -
Three members of the human pyruvate dehydrogenase kinase gene family are direct targets of the peroxisome proliferator-activated receptor beta/delta
Degenhardt T, Saramäki A, Malinen M, Rieck M, Väisänen S, Huotari A, Herzig K-H, Müller R, Carlberg C. 2007. Journal of molecular biology. 372: 341-355 -
Vitamins as hormones
Reichrath J, Lehmann B, Carlberg C, Varani J, Zouboulis CC. 2007. Hormone and metabolic research. 39: 71-84 -
An integrated biological approach to nuclear receptor signaling in physiological control and disease
Carlberg C, Dunlop TW. 2006. Critical reviews in eukaryotic gene expression. 16: 1-22 -
Analysis of the 5-lipoxygenase promoter and characterization of a vitamin D receptor binding site
Sorg BL, Klan N, Seuter S, Dishart D, Rådmark O, Habenicht A, Carlberg C, Werz O, Steinhilber D. 2006. Biochimica et biophysica acta: international journal of biochemistry and biophysics. 1761: 686-697 -
Detailed molecular understanding of agonistic and antagonistic vitamin D receptor ligands
Carlberg C, Molnar F. 2006. Current topics in medicinal chemistry. 6: 1243-53 -
Epigenetic corruption of VDR signalling in malignancy
Abedin SA, Banwell CM, Colston KW, Carlberg C, Campbell MJ. 2006. Anticancer research. 26: 2557-2566 -
Regulation of the human p21(waf1/cip1) gene promoter via multiple binding sites for p53 and the vitamin D3 receptor
Saramäki A, Banwell CM, Campbell MJ, Carlberg C. 2006. Nucleic acids research. 34: 543-554 -
The impact of chromatin organization of vitamin D target genes
Carlberg C, Dunlop TW. 2006. Anticancer research. 26: 2637-2646 -
The insulin-like growth factor-binding protein 1 gene is a primary target of peroxisome proliferator-activated receptors
Degenhardt T, Matilainen M, Herzig K-H, Dunlop TW, Carlberg C. 2006. Journal of biological chemistry. 281: 39607-39619 -
Vitamin D Receptor Agonists Specifically Modulate the Volume of the Ligand-Binding Pocket
Molnar Ferdinand, Peräkylä Mikael, Carlberg Carsten. 2006. Journal of biological chemistry. 281: 10516-10526 -
Vitamin D receptor agonists specifically modulate the volume of the ligand-binding pocket
Molnár F, Peräkylä M, Carlberg C. 2006. Journal of biological chemistry. 281: 10516-10526 -
A role of melatonin in neuroectodermal-mesodermal interactions: the hair follicle synthesizes melatonin and expresses functional melatonin receptors
Kobayashi H, Kromminga A, Dunlop TW, Tychsen B, Conrad F, Suzuki N, Memezava A, Bettermann A, Aiba S, Carlberg C, Paus R. 2005. Faseb journal. 19: 1710-1712 -
Antagonist- and inverse agonist-driven interactions of the vitamin D receptor and the constitutive androstane receptor with corepressor protein
Lempiäinen H, Molnár F, Macias Gonzalez M, Peräkylä M, Carlberg C. 2005. Molecular endocrinology. 19: 2258-2272 -
Gene regulatory potential of nonsteroidal vitamin D receptor ligands
Peräkylä M, Malinen M, Herzig K-H, Carlberg C. 2005. Molecular endocrinology. 19: 2060-2073 -
Identification of pregnane X reseptor binding sites in the regulatory regions of genes involved in bile acid homeostasis
Frank C, Makkonen H, Dunlop TW, Matilainen M, Väisänen S, Carlberg C. 2005. Journal of molecular biology. 346: 506-519 -
Molecular basis of the diversity of vitamin D target genes
Carlberg C, Dunlop TW, Frank C, Väisänen S. Teoksessa: Feldman D, Wesley Pike J, Glorieux FH(toim.) , 2005. Vitamin D. s. 313-325. Elsevier Academic Press -
Regulation of multiple insulin-like growth factor binding protein genes by 1[alpha],25-dihydroxyvitamin D3
Matilainen M, Malinen M, Saavalainen K, Carlberg C. 2005. Nucleic acids research. 33: 5521-5532 -
Regulation of the human cyclin C gene via multiple vitamin D3-responsive regions in its promoter
Sinkkonen L, Malinen M, Saavalainen K, Väisänen S, Carlberg C. 2005. Nucleic acids research. 33: 2440-2451 -
Spatio-temporal activation of chromatin on the human CYP24 gene promoter in the presence of 1[alpha],25-dihydroxyvitamin D3
Väisänen S, Dunlop TW, Sinkkonen L, Frank C, Carlberg C. 2005. Journal of molecular biology. 350: 65-77 -
Structural determinants of the agonist-independent association of human peroxisome proliferator-activated receptors with coactivators
Molnár F, Matilainen M, Carlberg C. 2005. Journal of biological chemistry. 280: 26543-26556 -
The human hyaluronan synthase 2 gene is a primary retinoic acid and epidermal growth factor responding gene
Saavalainen K, Pasonen-Seppänen S, Dunlop TW, Tammi R, Tammi MI, Carlberg C. 2005. Journal of biological chemistry. 280: 14636-14644 -
The human peroxisome proliferator-activated receptor [delta] gene is a primary target of 1[alpha],25-dihydroxyvitamin D3 and its nuclear receptor
Dunlop T, Väisänen S, Frank C, Molnár F, Sinkkonen L, Carlberg C. 2005. Journal of molecular biology. 349: 248-260 -
A structural basis for the species-specific antagonism of 26,23-lactones on vitamin D signaling
Peräkylä M, Molnar F, Carlberg C. 2004. Chemistry and biology. 11: 1147-1156 -
Agonist-dependent and agonist-independent transactivations of the human constitutive androstane receptor are modulated by specific amino acid pairs
Frank C, Molnar F, Matilainen M, Lempiäinen H, Carlberg C. 2004. Journal of biological chemistry. 279: 33558-33566 -
Ligand-mediated conformational changes of the VDR are required for gene transactivation
Carlberg C. 2004. Journal of steroid biochemistry and molecular biology. 89-90: 227-232 -
Principles of gene regulation by bioactive lipids through members of the nuclear receptor family
Carlberg C. Teoksessa: Schmitz ML, Bacher S(toim.) , 2004. Mechanisms of Signal Transduction and Inducible Gene Expression. s. 77-95. Research signpost -
The genes of the coactivator TIF2 and the corepressor SMRT are primary 1alfa,25(OH)2D3 targets
Dunlop TW, Väisänen S, Frank C, Carlberg C. 2004. Journal of steroid biochemistry and molecular biology. 89-90: 257-260 -
The highly conserved region of the co-repressor Sin3A functionally interacts with the co-repressor alien
Moehren U, Dressel U, Reeb CA, Väisänen S, Dunlop TW, Carlberg C, Baniahmad A. 2004. Nucleic acids research. 32: 2995-3004 -
Using chromatin immunoprecipitation to monitor 1alfa,25-dihydroxyvitamin D3-dependent chromatin activity on the human CYP24 promoter
Väisänen S, Dunlop TW, Frank C, Carlberg C. 2004. Journal of steroid biochemistry and molecular biology. 89-90: 277-279 -
Characterization of DNA complexes formed by the nuclear receptor constitutive androstane receptor
Frank C, Macias Gonzalez M, Oinonen C, Dunlop TW, Carlberg C. 2003. Journal of biological chemistry. 278: 43299-43310 -
Corepressor excess shifts the two-side chain vitamin D analog gemini from an agonist to an inverse agonist of the vitamin D receptor
Macias Gonzalez M, Samenfeld P, Peräkylä M, Carlberg C. 2003. Molecular endocrinology. 17: 2028-2038 -
Current understanding of the function of the nuclear vitamin D receptor in response to its natural and synthetic ligands
Carlberg C. Teoksessa: J Reichrath, M Friedrich, W Tilgen(toim.) , 2003. Vitamin D Analogs in Cancer Prevention and Therapy. s. 29-42. Springer-Verlag -
Molecular basis of the selective activity of vitamin D analogues
Carlberg C. 2003. Journal of cellular biochemistry. 88: 274-281 -
New vitamin D receptor ligands
Carlberg C, Mourino A. 2003. Expert opinion on therapeutic patents. 13: 761-772 -
Structural evaluation of the agonistic action of a vitamin D analog with two side chains binding to the nuclear vitamin D receptor
Väisänen S, Peräkylä M, Kärkkäinen JI, Uskokovic MR, Carlberg C. 2003. Molecular pharmacology. 63: 1230-1237 -
The critical role of carboxy-terminal amino acids in ligand-dependent and -independent transactivation of the constitutive androstane receptor
Andersin T, Väisänen S, Carlberg C. 2003. Molecular endocrinology. 17: 234-246 -
Critical role of helix 12 of the vitamin D3 receptor for the partial agonism of carboxylic ester antagonists
Väisänen S, Peräkylä M, Kärkkäinen JI, Steinmeyer A, Carlberg C. 2002. Journal of molecular biology. 315: 229-238 -
Cross-repression, a functional consequence of the physical interaction of non-liganded nuclear receptors and POU domain transcription factors
Macias Gonzalez M, Carlberg C. 2002. Journal of biological chemistry. 277: 18501-18509 -
Differential nuclear receptor signalling from DR4-type response elements
Quack M, Frank C, Carlberg C. 2002. Journal of cellular biochemistry. 86: 601-612 -
Modulation of mouse and human phenobarbital-responsive enhancer module by nuclear receptors
Mäkinen J, Frank C, Jyrkkärinne J, Gynther J, Carlberg C, Honkakoski P. 2002. Molecular pharmacology. 62: 366-378 -
Orphan nuclear receptor binding site in the human inducible nitric oxide synthase promoter mediates responsiveness to steroid and xenobiotic ligands
Toell A, Kröncke K-D, Kleinert H, Carlberg C. 2002. Journal of cellular biochemistry. 85: 72-82 -
Different molecular mechanisms of vitamin D3 receptor antagonists
Toell A, Macias Gonzalez M, Ruf D, Steinmeyer A, Ishizuka S, Carlberg C. 2001. Molecular pharmacology. 59: 1478-1485 -
Peroxisome proliferator-activated receptor delta is a specific sensor for teratogenic valproic acid derivatives
Lampen A, Carlberg C, Nau H. 2001. European journal of pharmacology. 431: 25-33 -
Single thyroid hormone receptor monomers are competent for co-activator-mediated transactivation
Quack M, Carlberg C. 2001. Biochemical journal. 360: 387-393 -
Vitamin D and cancer: Effects of 1,25(OH)2D3 and its analogs on growth control and tumorigenesis
Mork Hansen C , Binderup L, Hamberg KJ, Carlberg C. 2001. FRONTIERS IN BIOSCIENCE. 6: d820-d848