Christopher Asquith
Yliopistotutkija
Farmasian laitos, Terveystieteiden tiedekunta
[email protected] | 050 400 3138
Tutkimusryhmät
Julkaisut
14/14 kappaletta-
Medicinal chemistry applications of the Dimroth Rearrangement to the synthesis of biologically active compounds
Pozzetti, Luca; Pinhammer, Maja M; Asquith, Christopher RM, 2025, European journal of medicinal chemistry, 289, 117399. A2 Katsausartikkeli tieteellisessä aikakauslehdessä -
Myeloid-specific CAMKK2 deficiency protects against diet-induced obesity and insulin resistance by rewiring metabolic gene expression and enhancing energy expenditure
Ortiz, Andrea R; Nay, Kevin; Stork, Brittany A; Dean, Adam M; Hartig, Sean M; Coarfa, Cristian; Tegegne, Surafel; Asquith, Christopher RM; Frigo, Daniel E; York, Brian; Means, Anthony R; Febbraio, Mark A; Scott, John W, 2025, Molecular metabolism, 101, 102250. A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä -
PIP4K2C inhibition reverses autophagic flux impairment induced by SARS-CoV-2
Karim, Marwah; Mishra, Manjari; Lo, Chieh Wen; Saul, Sirle; Cagirici, Halise Busra; Gourdelier, Manon; Ghita, Luca; Ojha, Amrita; Tran, Do Hoang Nhu; Agrawal, Aditi; McGraw, Connor; East, Michael P; Gammeltoft, Karen Anbro; Sahoo, Malaya Kumar; Mooney, Nancie A; Johnson, Gary L; Das, Soumita; Leyssen, Pieter; Neyts, Johan; Chiu, Winston; Cohen, Courtney A; Bukh, Jens; Gottwein, Judith; Dye, John M; Neff, Norma; Jackson, Peter K; Pinsky, Benjamin A; Laitinen, Tuomo; Pantsar, Tatu; Poso, Antti; Za, 2025, Nature communications, 16, 1, 6397. A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä -
Discovery and optimization of narrow spectrum inhibitors of Tousled like kinase 2 (TLK2) using quantitative structure activity relationships
Asquith, Christopher R M; East, Michael P; Laitinen, Tuomo; Alamillo-Ferrer, Carla; Hartikainen, Erkka; Wells, Carrow I; Axtman, Alison D; Drewry, David H; Tizzard, Graham J; Poso, Antti; Willson, Timothy M; Johnson, Gary L, 2024, European journal of medicinal chemistry, 271, 116357. A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä -
Enhancing colistin efficacy against Salmonella infections with a quinazoline-based dual therapeutic strategy
Lobertti, Carlos A; Gizzi, Fernán O; Magni, Christian; Rial, Analía; Chabalgoity, José A; Yim, Lucía; Blancato, Víctor S; Asquith, Christopher R M; García Véscovi, Eleonora, 2024, Scientific reports, 14, 1, 5148. A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä -
Pentathiepins are an understudied molecular prism of biological activities
Pozzetti, Luca; Asquith, Christopher RM, 2024, Archiv der pharmazie, 357, 12, 2400646. A2 Katsausartikkeli tieteellisessä aikakauslehdessä -
TLK2: a target for cancer and viral latency
Pozzetti, Luca; East, Michael P; Laitinen, Tuomo; Asquith, Christopher RM, 2024, Nature reviews drug discovery, 23, 12, 886-886, . B1 Kirjoitus tieteellisessä aikakauslehdessä -
The Synthesis and Biological Applications of the 1,2,3-Dithiazole Scaffold
Kalogirou, Andreas S; Oh, Hans J; Asquith, Christopher RM, 2023, Molecules, 28, 7, 3193. A2 Katsausartikkeli tieteellisessä aikakauslehdessä -
Utilization of Supervised Machine Learning to Understand Kinase Inhibitor Toxophore Profiles
Bieberich, Andrew A; Asquith, Christopher RM, 2023, International journal of molecular sciences, 24, 6, 5088. A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä -
Numb-associated kinases are required for SARS-CoV-2 infection and are cellular targets for antiviral strategies
Karim, Marwah; Saul, Sirle; Ghita, Luca; Sahoo, Malaya Kumar; Ye, Chengjin; Bhalla, Nishank; Lo, Chieh-Wen; Jin, Jing; Park, Jun-Gyu; Martinez-Gualda, Belén; East, Michael Patrick; Johnson, Gary L; Pinsky, Benjamin A; Martinez-Sobrido, Luis; Asquith, Christopher RM; Narayanan, Aarthi; De Jonghe, Steven; Einav, Shirit, 2022, Antiviral research, 204, 105367. A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä