Juha Töyräs

Afara, Isaac O; Sarin, Jaakko K; Ojanen, Simo; Finnilä, Mikko A J; Herzog, Walter; Saarakkala, Simo; Korhonen Rami K; Töyräs, Juha. 2020. Machine Learning Classification of Articular Cartilage Integrity Using Near Infrared Spectroscopy Cellular and molecular bioengineering 13 3: 219-228. 2020

Leino, A; Westeren-Punnonen, S; Töyräs, J; Myllymaa, S; Leppänen, T; Ylä-Herttuala, S; Muraja-Murro, A; Kantanen, AM; Autere, J; Jäkälä, P; Mervaala, E; Myllymaa, K. 2020. Acute stroke and TIA patients have specific polygraphic features of obstructive sleep apnea Sleep and breathing [Epub ahead of print 14 Jan 2020]: 1-11. 2020

Ala-Myllymäki, Juho; Paakkonen, Tommi; Joukainen, Antti; Kröger, Heikki; Lehenkari, Petri; Töyräs, Juha; Afara, Isaac O. 2020. Near-Infrared Spectroscopy for Mapping of Human Meniscus Biochemical Constituents Annals of biomedical engineering [Online ahead of print 2020 Jul 27]: 1-8. 2020

Torniainen, J; Afara, IO; Prakash, M; Sarin, JK; Stenroth, L; Töyräs, J. 2020. Open-source python module for automated preprocessing of near infrared spectroscopic data Analytica chimica acta 1108: 1-9. 2020

Ristaniemi, A; Torniainen, J; Stenroth, L; Finnilä, MAJ; Paakkonen, T; Töyräs, J; Korhonen, RK. 2020. Comparison of water, hydroxyproline, uronic acid and elastin contents of bovine knee ligaments and patellar tendon and their relationships with biomechanical properties Journal of the mechanical behavior of biomedical materials 104: 103639. 2020

Nykänen, Olli; Leskinen, Henri P P; Finnilä, Mikko; Karhula, Sakari S; Turunen, Mikael J; Töyräs, Juha; Saarakkala, Simo; Nissi, Mikko J. 2020. The bright ultra-short echo time SWIFT MRI signal at the osteochondral junction is not located in the calcified cartilage Journal of orthopaedic research [Online ahead of print]: -. 2020

Nippolainen, Ervin; Shaikh, Rubina; Virtanen, Vesa; Rieppo, Lassi; Saarakkala, Simo; Töyräs, Juha; Afara, Isaac. 2020. Near Infrared Spectroscopy Enables Differentiation of Mechanically and Enzymatically Induced Cartilage Injuries Annals of biomedical engineering [Online ahead of print 2020 Apr 16]: 1-11. 2020

Nikkonen, Sami; Korkalainen, Henri; Kainulainen, Samu; Myllymaa, Sami; Leino, Akseli; Kalevo, Laura; Oksenberg, Arie; Leppänen, Timo; Töyräs, Juha. 2020. Estimating daytime sleepiness with previous night EEG, EOG and EMG spectrograms in patients with suspected sleep apnea using a convolutional neural network Sleep [Online ahead of print]: -. 2020

Myller, KAH; Korhonen, R; Töyräs, J; Tanska, P; Väänänen, S; Jurvelin, JS; Saarakkala, S; Mononen, ME. 2020. Clinical Contrast-enhanced Computed Tomography with Semiautomatic Segmentation Provides Feasible Input for Computational Models of the Knee Joint Journal of biomechanical engineering 142 5: 051001. 2020

Mid-infrared and Near infrared spectroscopic analysis of mechanically and enzymatically damaged cartilage. Nippolainen, Ervin; Shaikh, Rubina; Virtanen, Vesa; Rieppo, Lassi; Afara, Isaac; Saarakkala, Simo; Töyräs, Juha / Proceedings Biophotonics Congress: Optics in the Life Sciences Congress 2019. 2020. 2020

Leppänen, T; Kulkas, A; Töyräs, J; Myllymaa, S; Gadoth, N; Oksenberg, A. 2020. Polysomnographic characteristics of severe obstructive sleep apnea vary significantly between hypertensive and normotensive patients of both genders Sleep and breathing [Online ahead of print 2020 Apr 5]: 1-12. 2020

Mid-infrared spectroscopic assessment of cartilage degeneration. Shaikh, Rubina; Nippolainen, Ervin; Virtanen, Vesa; Rieppo, Lassi; Haas, Julian; Mizaikoff, Boris; Artyushenko, Viacheslav; Bibikova, Olga; Afara, Isaac; Saarakkala, Simo; Töyräs, Juha / Proceedings Biophotonics Congress: Optics in the Life Sciences Congress 2019. 2020. 2020

Kulkas, Antti; Duce, Brett; Töyräs, Juha; Seppä, Juha; Leppänen, Timo. 2020. Comparison of the effect of weight change, simulated computational continuous positive airway pressure treatment and positional therapy on severity of sleep apnea Journal of sleep research [Online ahead of print 2020 Jun 18]: e13070. 2020

Husso, Minna; Afara, Isaac O; Nissi, Mikko J; Kuivanen, Antti; Halonen, Paavo; Tarkia, Miikka; Teuho, Jarmo; Saunavaara, Virva; Vainio, Pauli; Sipola, Petri; Manninen, Hannu; Ylä-Herttuala, Seppo; Knuuti, Juhani; Töyräs, Juha. 2020. Quantification of Myocardial Blood Flow by Machine Learning Analysis of Modified Dual Bolus MRI Examination Annals of biomedical engineering Published: 20 August 2020: 1-10. 2020

Bhattarai, Abhisek; Mäkelä, Janne T A; Pouran, Behdad; Kröger, Heikki; Weinans, Harrie; Grinstaff, Mark W; Töyräs, Juha; Turunen, Mikael J. 2020. Effects of Human Articular Cartilage Constituents on Simultaneous Diffusion of Cationic and Non-ionic Contrast Agents Journal of orthopaedic research First published: 07 August 2020: -. 2020

Korkalainen, H; Aakko, J; Duce, B; Kainulainen, S; Leino, A; Nikkonen, S; Afara, I O; Myllymaa, S; Töyräs, J; Leppänen, T. 2020. Deep learning enables sleep staging from photoplethysmogram for patients with suspected sleep apnea Sleep [Online ahead of print]: -. 2020

Bolcos, PO; Mononen, ME; Tanaka, MS; Yang, M; Suomalainen, JS; Nissi, MJ; Töyräs, J; Ma, B; Li, X; Korhonen, RK. 2020. Identification of locations susceptible to osteoarthritis in patients with anterior cruciate ligament reconstruction: Combining knee joint computational modelling with follow-up T1p and T2 imaging Clinical biomechanics In Press, Corrected Proof 27.8.19: pp 1-10. 2020

Duce, Brett; Kulkas, Antti; Töyräs, Juha; Terrill, Philip; Hukins, Craig. 2020. Longer duration electroencephalogram arousals have a better relationship with impaired vigilance and health status in obstructive sleep apnoea Sleep and breathing [Online ahead of print 2020 May 30]: 1-8. 2020

Bhattarai, Abhisek; Pouran, Behdad; Mäkelä, Janne T A; Shaikh, Rubina; Honkanen, Miitu K M; Prakash, Mithilesh; Kröger, Heikki; Grinstaff, Mark W; Weinans, Harrie; Jurvelin, Jukka S; Töyräs, Juha. 2020. Dual Contrast in Computed Tomography Allows Earlier Characterization of Articular Cartilage over Single Contrast Journal of orthopaedic research [Online ahead of print]: -. 2020

Kainulainen, S; Duce, B; Korkalainen, H; Oksenberg, A; Leino, A; Arnardottir, E; Kulkas, A; Myllymaa, S; Töyräs, J; Leppänen, T. 2020. Severe Desaturations Increase PVT-based Median Reaction Time and Number of Lapses in OSA Patients European respiratory journal 55: 1901849. 2020

Kainulainen, Samu; Töyräs, Juha; Oksenberg, Arie; Korkalainen, Henri; Afara, Isaac O; Leino, Akseli; Kalevo, Laura; Nikkonen, Sami; Gadoth, Natan; Kulkas, Antti; Myllymaa, Sami; Leppänen, Timo. 2020. Power spectral densities of nocturnal pulse oximetry signals differ in OSA patients with and without daytime sleepiness Sleep medicine 73: 231-237. 2020

Kajabi, Abdul Wahed; Casula, Victor; Sarin, Jaakko K; Ketola, Juuso H; Nykänen, Olli; Te Moller, Nikae C R; Mancini, Irina A D; Visser, Jetze; Brommer, Harold; René van Weeren, P; Malda, Jos; Töyräs, Juha; Nieminen, Miika T; Nissi, Mikko J. 2020. Evaluation of articular cartilage with quantitative MRI in an equine model of post-traumatic osteoarthritis Journal of orthopaedic research [Online ahead of print 16 June 20]: 1-11. 2020

Kalevo, Laura; Miettinen, Tomi; Leino, Akseli; Kainulainen, Samu; Korkalainen, Henri; Myllymaa, Katja; Töyräs, Juha; Leppänen, Timo; Laitinen, Tiina; Myllymaa, Sami. 2020. Effect of sweating on electrode-skin contact impedances and artifacts in EEG recordings with various screen-printed Ag/Agcl electrodes IEEE access 8: 50934-50943. 2020

Miettinen, T; Myllymaa, K; Muraja-Murro, A; Westeren-Punnonen, S; Hukkanen, T; Töyräs, J; Lappalainen, R; Mervaala, E; Sipilä, K; Myllymaa, S. 2019. Polysomnographic scoring of sleep bruxism events is accurate even in the absence of video recording but unreliable with EMG-only setups Sleep and breathing [First Online: 12 August 2019]: 1-12. 2019

Stenroth, Lauri; Sefa, Sandra; Arokoski, Jari; Töyräs, Juha. 2019. Does Magnetic Resonance Imaging Provide Superior Reliability for Achilles and Patellar Tendon Cross-Sectional Area Measurements Compared with Ultrasound Imaging? Ultrasound in medicine and biology 45 12: 3186-3198. 2019

Saukko, AEA; Turunen, MJ; Honkanen, MKM; Lovric, G; Tiitu, V; Honkanen, JTJ; Grinstaff, MW; Jurvelin, JS; Töyräs, J. 2019. Simultaneous Quantitation of Cationic and Non-ionic Contrast Agents in Articular Cartilage Using Synchrotron MicroCT Imaging Scientific reports 9 1: 7118. 2019

Sarin, JK; Torniainen, J; Prakash, M; Rieppo, L; Afara, IO; Töyräs, J. 2019. Dataset on equine cartilage near infrared spectra, composition, and functional properties Scientific data 6 1: 164. 2019

Sarin, JK; Nykänen, O; Tiitu, V; Mancini, IAD; Brommer, H; Visser, J; Malda, J; van Weeren, PR; Afara, IO; Töyräs, J. 2019. Arthroscopic Determination of Cartilage Proteoglycan Content and Collagen Network Structure with Near-Infrared Spectroscopy Annals of biomedical engineering 47 8: 1815-1826. 2019

Prakash, M; Joukainen, A; Torniainen, J; Honkanen, MKM; Rieppo, L; Afara, IO; Kröger, H; Töyräs, J; Sarin, JK. 2019. Near infrared spectroscopy enables quantitative evaluation of human cartilage biomechanical properties during arthroscopy Osteoarthritis and cartilage 27 8: 1235-1243. 2019

Oksenberg, A; Gadoth, N; Töyräs, J; Leppänen, T. 2019. Prevalence and characteristics of positional obstructive sleep apnea (POSA) in patients with severe OSA Sleep and breathing [First Online: 20 July 2019]: 1-9. 2019

Nykänen, O; Sarin, JK; Ketola, JH; Leskinen, H; te Moller, NCR; Tiitu, V; Mancini, IAD; Visser, J; Brommer, H; van Weeren, P René; Malda, J; Töyräs, J; Nissi, MJ. 2019. T2* and quantitative susceptibility mapping in an equine model of post-traumatic osteoarthritis: assessment of mechanical and structural properties of articular cartilage Osteoarthritis and cartilage 27 10: 1481-1490. 2019

Nikkonen, S; Afara, IO; Leppänen, T; Töyräs, J. 2019. Artificial neural network analysis of the oxygen saturation signal enables accurate diagnostics of sleep apnea Scientific reports 9 1: 13200. 2019

Myller, KAH; Korhonen, RK; Töyräs, J; Salo, J; Jurvelin, JS; Venäläinen, MS. 2019. Computational evaluation of altered biomechanics related to articular cartilage lesions observed in vivo Journal of orthopaedic research 37 5: 1042-1051. 2019

Nikkonen, S; Töyräs, J; Mervaala, E; Myllymaa, S; Terrill, P; Leppänen, T. 2019. Intra-night variation in apnea-hypopnea index affects diagnostics and prognostics of obstructive sleep apnea Sleep and breathing 2020; 24: 379-386. 2019

Mancini, IAD; Rieppo, L; Pouran, B; Afara, IO; Braganca, FMS; van Rijen, MHP; Kik, M; Weinans, H; Toyras, J; van Weeren, PR; Malda, J. 2019. Effects of body mass on microstructural features of the osteochondral unit: A comparative analysis of 37 mammalian species Bone 127: 664-673. 2019

Husso, M; Nissi, MJ; Kuivanen, A; Halonen, P; Tarkia, M; Teuho, J; Saunavaara, V; Vainio, P; Sipola, P; Manninen, H; Ylä-Herttuala, S; Knuuti, J; Töyräs, J. 2019. Quantification of porcine myocardial perfusion with modified dual bolus MRI - a prospective study with a PET reference Bmc medical imaging 19 1: 58. 2019

Leppänen, Timo; Kulkas, Antti; Töyräs, Juha. 2019. The hypoxic burden: also known as the desaturation severity parameter European heart journal 40 35: 2991-2993. 2019

Honkanen, MKM; Saukko, AEA; Turunen, MJ; Shaikh, R; Prakash, M; Lovric, G; Joukainen, A; Kröger, H; Grinstaff, MW; Töyräs, J. 2019. Synchrotron microCT reveals the potential of the dual contrast technique for quantitative assessment of human articular cartilage composition Journal of orthopaedic research 2020; 38 3: 563-573. 2019

Honkanen, MKM; Saukko, AEA; Turunen, MJ; Xu, W; Lovric, G; Honkanen, JTJ; Grinstaff, MW; Lehto, VP; Töyräs, J. 2019. Triple Contrast CT Method Enables Simultaneous Evaluation of Articular Cartilage Composition and Segmentation Annals of biomedical engineering 2020; 48 2: 556-567. 2019

Honkanen, MKM; Matikka, H; Honkanen, JTJ; Bhattarai, A; Grinstaff, MW; Joukainen, A; Kröger, H; Jurvelin, JS; Töyräs, J. 2019. Imaging of Proteoglycan and Water Contents in Human Articular Cartilage with Full-Body CT Using Dual Contrast Technique Journal of orthopaedic research 37 5: 1059-1070. 2019

Kainulainen, S; Töyräs, J; Oksenberg, A; Korkalainen, H; Sefa, S; Kulkas, A; Leppänen, T. 2019. Severity of desaturations reflects OSA-related daytime sleepiness better than AHI Journal of clinical sleep medicine 15 8: 1135-1142. 2019

Kalevo, Laura; Miettinen, Tomi; Leino, Akseli; Kainulainen, Samu; Myllymaa, Katja; Toyras, Juha; Leppanen, Timo; Myllymaa, Sami. 2019. Improved Sweat Artifact Tolerance of Screen-Printed EEG Electrodes by Material Selection-Comparison of Electrochemical Properties in Artificial Sweat IEEE access 7: 133237-133247. 2019

Korkalainen, H; Töyräs, J; Nikkonen, S; Leppänen, T. 2019. Mortality-risk-based apnea-hypopnea index thresholds for diagnostics of obstructive sleep apnea Journal of sleep research 28 6: e12855. 2019

Garcia, João P; Longoni, Alessia; Gawlitta, Debby; Rosenberg, Antoine J W P; Grinstaff, Mark W; Töyräs, Juha; Weinans, Harrie; Creemers, Laura B; Pouran, Behdad. 2019. Contrast enhanced computed tomography for real-time quantification of glycosaminoglycans in cartilage tissue engineered constructs Acta biomaterialia 100: 202-212. 2019

Korkalainen, Henri; Aakko, Juhani; Nikkonen, Sami; Kainulainen, Samu; Leino, Akseli; Duce, Brett; Afara, Isaac Oluwaseun; Myllymaa, Sami; Töyräs, Juha; Leppänen, Timo. 2019. Accurate Deep Learning-Based Sleep Staging in a Clinical Population with Suspected Obstructive Sleep Apnea IEEE journal of biomedical and health informatics [Epub ahead of print 19 Dec 2019]: 1-9. 2019

Torniainen, Jari; Ristaniemi, Aapo; Sarin, Jaakko K; Mikkonen, Santtu; Afara, Isaac O; Stenroth, Lauri; Korhonen, Rami K; Töyräs, Juha. 2018. Near Infrared Spectroscopic Evaluation of Ligament and Tendon Biomechanical Properties ANNALS OF BIOMEDICAL ENGINEERING 2019; 47 1: 213-222. 2018

Spectroscopic Evaluation of Post-Traumatic Osteoarthritis in Shetland Ponies. Sarin, Jaakko K; te Moller, Nikae; Brommer, Harold; van Weeren, René; Mancini, Irina; Malda, Josa; Afara, Isaac O; Töyräs, Juha / Optical Tomography and Spectroscopy 2018. 2018. 2018

Sarin, Jaakko K; Te Moller, Nikae CR; Mancini, Irina AD; Brommer, Harold; Visser, Jetze; Malda, Jos; van Weeren, PR; Afara, Isaac O; Töyräs, Juha. 2018. Arthroscopic near infrared spectroscopy enables simultaneous quantitative evaluation of articular cartilage and subchondral bone in vivo Scientific reports 8 1: 13409. 2018

Ryynänen, Olli-Pekka; Leppänen, Timo; Kekolahti, Pekka; Mervaala, Esa; Töyräs, Juha. 2018. Bayesian Network Model to Evaluate the Effectiveness of Continuous Positive Airway Pressure Treatment of Sleep Apnea Healthcare Informatics Research 24 4: 346-358. 2018

Prakash, M; Sarin, JK; Rieppo, L; Afara IO; Töyräs, J. 2018. Accounting for spatial dependency in multivariate spectroscopic data CHEMOMETRICS AND INTELLIGENT LABORATORY SYSTEMS 182: 166-171. 2018

Pouran, Behdad; Arbabi, Vahid; Bajpayee, Ambika G; van Tiel, Jasper; Töyras, Juha; Jurvelin, Jukka S; Malda, Jos; Zadpoor, Amir A; Weinans, Harrie. 2018. Multi-scale imaging techniques to investigate solute transport across articular cartilage JOURNAL OF BIOMECHANICS 78: 10-20. 2018

Nykänen, O; Rieppo, L; Töyräs, J; Kolehmainen, V; Saarakkala, S; Shmueli, K; Nissi, MJ. 2018. Quantitative susceptibility mapping of articular cartilage: Ex vivo findings at multiple orientations and following different degradation treatments Magnetic resonance in medicine 80 6: 2702-2716. 2018

Near-infrared spectroscopy: A potential tool for mapping meniscus properties. Ala-Myllymäki, Juho P.; Töyräs, Juha; Afara, Isaac O. / Biophotonics Congress: Biomedical Optics Congress 2018 (Microscopy/Translational/Brain/OTS). 2018. 2018

Near-infrared spectroscopy based arthroscopic evaluation of human knee joint cartilage, through automated selection of an anatomically specific regression model. Prakash, Mithilesh; Joukainen, Antti; Sarin, Jaakko; Rieppo, Lassi; Afara, Isaac; Töyräs, Juha / Optical Tomography and Spectroscopy 2018. 2018. 2018

Miettinen, Tomi; Myllymaa, Katja; Hukkanen, Taina; Töyräs, Juha; Sipilä, Kirsi; Myllymaa, Sami. 2018. Home Polysomnography Reveals a First-Night Effect in Patients With Low Sleep Bruxism Activity Journal of clinical sleep medicine 14 8: 1377-1386. 2018

Myller, Katariina AH; Honkanen, Juuso TJ; Jurvelin, Jukka S; Saarakkala, Simo; Töyräs, Juha; Väänänen, Sami P. 2018. Method for Segmentation of Knee Articular Cartilages Based on Contrast-Enhanced CT Images Annals of biomedical engineering 46 11: 1756-1767. 2018

Leppänen, Timo; Kulkas, Antti; Mervaala, Esa; Töyräs, Juha. 2018. Increase in Body Mass Index Decreases Duration of Apneas and Hypopneas in Obstructive Sleep Apnea Respiratory care 2019; 64 1: 77-84. 2018

Kulkas, Antti; Nikkonen, Sami; Töyräs, Juha; Mervaala, Esa; Leppänen, Timo. 2018. Simulation of Required CPAP Usage to Normalize AHI in Obstructive Sleep Apnea Patients. Teoksessa: Lhotska, L; Sukupova, L; Lackovic, I; Ibbott, G (toim.), World Congress on Medical Physics and Biomedical Engineering 2018, June 3-8, 2018, Prague, Czech Republic (Vol.2). Springer. IFMBE Proceedings 68/2. s. 129-132. 2018

Kulkas, Antti; Leppänen, Timo; Nikkonen, Sami; Oksenberg, Arie; Duce, Brett; Mervaala, Esa; Töyräs, Juha. 2018. Required CPAP usage time to normalize AHI in obstructive sleep apnea patients: a simulation study PHYSIOLOGICAL MEASUREMENT 39 11: 115009. 2018

Estimating Mechanical Properties of Bovine Knee Ligaments and Tendons with Near Infrared Spectroscopy. Torniainen, Jari E; Ristaniemi, Aapo; Stenroth, Lauri; Töyräs, Juha / Biophotonics Congress: Biomedical Optics Congress 2018 (Microscopy/Translational/Brain/OTS). 2018. 2018

Deep Learning Classification of Cartilage Integrity Using Near Infrared Spectroscopy. Afara, Isaac O.; Sarin, Jaakko K.; Ojanen, Simo; Finnilä, Mikko; Herzog, Walter; Saarakkala, Simo; Korhonen, Rami; Töyräs, Juha / Biophotonics Congress: Biomedical Optics Congress 2018 (Microscopy/Translational/Brain/OTS). 2018. 2018

Bolcos, PO; Mononen, ME; Mohammadi, A; Ebrahimi, M; Tanaka, MS; Samaan, MA; Souza, RB; Li, X; Suomalainen, JS; Jurvelin, JS; Töyräs, J; Korhonen, RK. 2018. Comparison between kinetic and kinetic-kinematic driven knee joint finite element models Scientific Reports 8: 17351. 2018

Bhattarai, A; Honkanen, JTJ; Myller, KAH; Prakash, M; Korhonen M; Saukko, AEA; Virén, T; Joukainen, A; Patwa, AN; Kröger, H; Grinstaf, MW; Jurvelin, JS; Töyräs, J;. 2018. Quantitative Dual Contrast CT Technique for Evaluation of Articular Cartilage Properties Annals of biomedical engineering 46 7: 1038-1046. 2018

Afara, IO; Florea, C; Olumegbon, IA; Eneh, CT; Malo, MKH; Korhonen, RK; Töyräs, J. 2018. Characterizing human subchondral bone properties using near-infrared (NIR) spectroscopy Scientific Reports 8 1: 9733. 2018

Leppänen, Timo; Kulkas, Antti; Oksenberg, Arie; Duce, Brett; Mervaala, Esa; Töyräs, Juha. 2018. Differences in arousal probability and duration after apnea and hypopnea events in adult obstructive sleep apnea patients PHYSIOLOGICAL MEASUREMENT 39 11: 114004. 2018

Rohrbach D, Inkinen SI, Zatloukalová J, Kadow-Romacker A, Joukainen A, Malo MK, Mamou J, Töyräs J, Raum K. 2017. Regular chondrocyte spacing is a potential cause for coherent ultrasound backscatter in human articular cartilage. The Journal of the Acoustical Society of America 141 5: 3105-3116. 2017

Prakash M, Sarin JK, Rieppo L, Afara IO, Töyräs J. 2017. Optimal Regression Method for Near-Infrared Spectroscopic Evaluation of Articular Cartilage. APPLIED SPECTROSCOPY 71 10: 2253-2262. 2017

Rieppo L, Kokkonen HT, Kulmala KAM, Kovanen V, Lammi MJ, Töyräs J, Saarakkala S. 2017. Infrared microspectroscopic determination of collagen cross-links in articular cartilage Journal of Biomedical Optics 22 3: 035007. 2017

Muraja-Murro Anu, Nieminen Outi, Julkunen Petro, Töyräs Juha, Laitinen Tomi, Mervaala Esa. 2017. Peri-apneic hemodynamic reactions in obstructive sleep apnea. PATHOPHYSIOLOGY 24 3: 197-203. 2017

Viren T, Honkanen JT, Danso EK, Rieppo L, Korhonen RK, Töyräs J. 2017. Ultrasound Assessment of Human Meniscus. ULTRASOUND IN MEDICINE AND BIOLOGY 43 9: 1753-1763. 2017

Sarin Jaakko K, Rieppo Lassi, Brommer Harold, Afara Isaac O, Saarakkala Simo, Töyräs Juha. 2017. Combination of optical coherence tomography and near infrared spectroscopy enhances determination of articular cartilage composition and structure. Scientific Reports 7 1: 10586. 2017

Sarin Jaakko Kalevi, Brommer Harold, Argüelles David, Puhakka Pia Henriikka, Inkinen Satu Irene, Afara Isaac Oluwaseun, Saarakkala Simo, Töyräs Juha. 2017. Multimodality scoring of chondral injuries in the equine fetlock joint ex vivo. OSTEOARTHRITIS AND CARTILAGE 25 5: 790-798. 2017

Sarin JK, Brommer H, Argüelles D, Puhakka PH, Inkinen SI, Afara IO, Saarakkala S, Töyräs J. 2017. Corrigendum to "Multimodality scoring of chondral injuries in the equine fetlock joint ex vivo" [Osteoarthritis Cartilage 25 (5) (2017 May) 790-798]. Osteoarthritis and cartilage 25 8: 1377-1378. 2017

Saukko Annina EA, Honkanen Juuso TJ, Xu Wujun, Väänänen Sami P, Jurvelin Jukka S, Lehto Vesa-Pekka, Töyräs Juha. 2017. Dual Contrast CT Method Enables Diagnostics of Cartilage Injuries and Degeneration Using a Single CT Image. ANNALS OF BIOMEDICAL ENGINEERING 45 12: 2857-2866. 2017

Ojanen X, Tanska P, Malo MKH, Isaksson H, Väänänen SP, Koistinen AP, Grassi L, Magnusson SP, Ribel-Madsen SM, Korhonen RK, Jurvelin JS, Töyräs J. 2017. Tissue viscoelasticity is related to tissue composition but may not fully predict the apparent-level viscoelasticity in human trabecular bone - An experimental and finite element study. JOURNAL OF BIOMECHANICS 65: 96-105. 2017

Lasanen, R; Malo, MKH; Airaksinen, O; Karhu, J; Töyräs, J; Julkunen, P. 2017. Infrared thermography reveals effect of working posture on skin temperature in office workers INTERNATIONAL JOURNAL OF OCCUPATIONAL SAFETY AND ERGONOMICS 2018; 24 3: 457-463. 2017

Miettinen T, Myllymaa K, Westeren-Punnonen S, Ahlberg J, Hukkanen T, Töyräs J, Lappalainen R, Mervaala E, Sipilä K, Myllymaa S. 2017. Success Rate and Technical Quality of Home Polysomnography with Self-Applicable Electrode Set in Subjects with Possible Sleep Bruxism IEEE journal of biomedical and health informatics 120; 22 4: 1124-1132. 2017

Miettinen T, Myllymaa K, Muraja-Murro A, Westeren-Punnonen S, Hukkanen T, Töyräs J, Lappalainen R, Mervaala E, Sipilä K, Myllymaa S. 2017. Screen-printed ambulatory electrode set enables accurate diagnostics of sleep bruxism. Journal of Sleep Research 2018; 27 1: 103-112. 2017

Majda D, Bhattarai A, Riikonen J, Napruszewska BD, Zimowska M, Michalik-Zym A, Töyräs J, Lehto V-P. 2017. New approach for determining cartilage pore size distribution: NaCl-thermoporometry. Microporous and Mesoporous Materials 241: 238-245. 2017

Leppänen Timo, Töyräs Juha, Mervaala Esa, Penzel Thomas, Kulkas Antti. 2017. Severity of individual obstruction events increases with age in patients with obstructive sleep apnea. SLEEP MEDICINE 37: 32-37. 2017

Kulkas Antti, Duce Brett, Leppänen Timo, Hukins Craig, Töyräs Juha. 2017. Severity of desaturation events differs between hypopnea and obstructive apnea events and is modulated by their duration in obstructive sleep apnea. Sleep and Breathing 21 4: 829-835. 2017

Kulkas Antti, Duce Brett, Leppänen Timo, Hukins Craig, Töyräs Juha. 2017. Gender differences in severity of desaturation events following hypopnea and obstructive apnea events in adults during sleep. PHYSIOLOGICAL MEASUREMENT 38 8: 1490-1502. 2017

Joukainen A, Virén T, Penttilä P, Liukkonen J, Puhakka PH, Kröger H, Töyräs J. 2017. Ultrasound Arthroscopy of Hip in Treatment of Osteochondritis Dissecans. Arthroscopy Techniques 6 4: e1063-e1068. 2017

Eneh Chibuzor TM, Afara Isaac O, Malo Markus KH, Jurvelin Jukka S, Töyräs Juha. 2017. Porosity predicted from ultrasound backscatter using multivariate analysis can improve accuracy of cortical bone thickness assessment. The Journal of the Acoustical Society of America 141 1: 575-585. 2017

Duce Brett, Kulkas Antti, Langton Christian, Töyräs Juha, Hukins Craig. 2017. The prevalence of REM-related obstructive sleep apnoea is reduced by the AASM 2012 hypopnoea criteria. Sleep and Breathing 2018; 22 1: 57-64. 2017

Ala-Myllymäki Juho, Danso Elvis K, Honkanen Juuso TJ, Korhonen Rami K, Töyräs J, Afara Isaac O. 2017. Optical spectroscopic characterization of human meniscus biomechanical properties. Journal of Biomedical Optics 22 12: 125008 (10 pages). 2017

Miettinen T, Myllymaa K, Westeren-Punnonen S, Ahlberg J, Hukkanen T, Töyräs J, Lappalainen R, Mervaala E, Sipilä K, Myllymaa S. 2017. At-home quantification of sleep characteristics with self-applicable facial electrode set. SLEEP MEDICINE 40 Supplement 1: e233-e234. 2017

Rautiainen J, Nieminen MT, Salo EN, Kokkonen HT, Mangia S, Michaeli S, Gröhn O, Jurvelin JS, Töyräs J, Nissi MJ. 2016. Effect of collagen cross-linking on quantitative MRI parameters of articular cartilage. OSTEOARTHRITIS AND CARTILAGE 24 9: 1656-1664. 2016

Myllymaa Sami, Muraja-Murro Anu, Westeren-Punnonen Susanna, Hukkanen Taina, Lappalainen Reijo, Mervaala Esa, Töyräs Juha, Sipilä Kirsi, Myllymaa Katja. 2016. Assessment of the suitability of using a forehead EEG electrode set and chin EMG electrodes for sleep staging in polysomnography. Journal of Sleep Research [Epub ahead of print 27 May 2016]: 1-10. 2016

Männicke Nils, Schöne Martin, Liukkonen Jukka, Fachet Dominik, Inkinen Satu, Malo Markus K, Oelze Michael L, Töyräs Juha, Jurvelin Jukka S, Raum Kay. 2016. Species-Independent Modeling of High-Frequency Ultrasound Backscatter in Hyaline Cartilage. ULTRASOUND IN MEDICINE AND BIOLOGY 42 6: 1375-1384. 2016

Ojanen X, Töyräs J, Inkinen SI, Malo MKH, Isaksson H, Jurvelin JS. 2016. Differences in acoustic impedance of fresh and embedded human trabecular bone samples - scanning acoustic microscopy and numerical evaluation. The Journal of the Acoustical Society of America 140 3: 1931-1936. 2016

Puhakka PH, te Moller NCR, Tanska P, Saarakkala S, Tiitu V, Korhonen RK, Brommer H, Virén T, Jurvelin JS, Töyräs J. 2016. Optical coherence tomography enables accurate measurement of equine cartilage thickness for determination of speed of sound. ACTA ORTHOPAEDICA 87 4: 418-424. 2016

Venäläinen MS, Mononen ME, Väänänen SP, Jurvelin JS, Töyräs J, Virén T, Korhonen RK. 2016. Effect of bone inhomogeneity on tibiofemoral contact mechanics during physiological loading. JOURNAL OF BIOMECHANICS 7 3: 1111-1120. 2016

Rieppo Lassi, Töyräs Juha, Saarakkala Simo. 2016. Vibrational spectroscopy of articular cartilage. Applied Spectroscopy Reviews [Published online 23 Aug 2016]: 1-18. 2016

Sarin Jaakko K, Amissah Michael, Brommer Harold, Argüelles David, Töyräs Juha, Afara Isaac O. 2016. Near Infrared Spectroscopic Mapping of Functional Properties of Equine Articular Cartilage. ANNALS OF BIOMEDICAL ENGINEERING 44 11: 3335-3345. 2016

Te Moller NC, Pitkänen M, Sarin JK, Väänänen S, Liukkonen J, Afara IO, Puhakka PH, Brommer H, Niemelä T, Tulamo RM, Arqüelles Capilla D, Töyräs J. 2016. Semi-automated International Cartilage Repair Society scoring of equine articular cartilage lesions in optical coherence tomography images. EQUINE VETERINARY JOURNAL [Epub ahead of print 20 Oct 2016]: -. 2016

Venäläinen Mikko S, Mononen Mika E, Salo Jari, Räsänen Lasse P, Jurvelin Jukka S, Töyräs Juha, Virén Tuomas, Korhonen Rami K. 2016. Quantitative Evaluation of the Mechanical Risks Caused by Focal Cartilage Defects in the Knee Scientific reports 6: 37538. 2016

Linder H, Malo MK, Liukkonen J, Jurvelin JS, Töyräs J. 2016. Phased-array ultrasound technology enhances accuracy of dual frequency ultrasound measurements - towards improved ultrasound bone diagnostics. JOURNAL OF MEDICAL ENGINEERING & TECHNOLOGY 40 6: 293-297. 2016

Myller Katariina AH, Turunen Mikael J, Honkanen Juuso TJ, Väänänen Sami P, Iivarinen Jarkko T, Salo Jari, Jurvelin Jukka S, Töyräs Juha. 2016. In Vivo Contrast-Enhanced Cone Beam CT Provides Quantitative Information on Articular Cartilage and Subchondral Bone. ANNALS OF BIOMEDICAL ENGINEERING [Epub ahead of print 19 Sept 2016]: 1-8. 2016

Stewart Rachel C, Honkanen Juuso TJ, Kokkonen Harri T, Tiitu Virpi, Saarakkala Simo, Joukainen Antti, Snyder Brian D, Jurvelin Jukka S, Grinstaff Mark W, Töyräs Juha. 2016. Contrast-Enhanced Computed Tomography Enables Quantitative Evaluation of Tissue Properties at Intrajoint Regions in Cadaveric Knee Cartilage. Cartilage 8 4: 391-399. 2016

Leppänen Timo, Töyräs Juha, Muraja-Murro Anu, Kupari Salla, Tiihonen Pekka, Mervaala Esa, Kulkas Antti. 2016. Length of Individual Apnea Events Is Increased by Supine Position and Modulated by Severity of Obstructive Sleep Apnea. Sleep Disorders 2016: 1-13. 2016

Halonen KS, Mononen ME, Jurvelin JS, Töyräs J, Klodowski A, Kulmala JP, Korhonen RK. 2016. Importance of patella, quadriceps forces, and depthwise cartilage structure on knee joint motion and cartilage response during gait. JOURNAL OF BIOMECHANICAL ENGINEERING 138 7: BIO-15-1348, 11 pages. 2016

Leppänen Timo, Särkkä Mikko, Kulkas Antti, Muraja-Murro Anu, Kupari Salla, Anttonen Meri, Tiihonen Pekka, Mervaala Esa, Töyräs Juha. 2016. RemLogic plug-in enables clinical application of apnea-hypopnea index adjusted for severity of individual obstruction events. JOURNAL OF MEDICAL ENGINEERING & TECHNOLOGY 40 3: 119-126. 2016

Danso EK, Oinas JM, Saarakkala S, Mikkonen S, Töyräs J, Korhonen RK. 2016. Structure-function relationships of human meniscus. Journal of the Mechanical Behavior of Biomedical Materials 67 March 2017: 51-60. 2016

Duce B, Kulkas A, Langton C, Töyräs J, Hukins C. 2016. The AASM 2012 recommended hypopnea criteria increase the incidence of obstructive sleep apnea but not the proportion of positional obstructive sleep apnea. SLEEP MEDICINE 26: 23-29. 2016

Eneh CTM, Malo MKH, Karjalainen JP, Liukkonen J, Töyräs J, Jurvelin JS. 2016. Effect of porosity, tissue density, and mechanical properties on radial sound speed in human cortical bone. MEDICAL PHYSICS 43 5: 2030-2039. 2016

Duce B, Kulkas A, Langton C, Töyräs J, Hukins C. 2016. Amsterdam positional OSA classification: the AASM 2012 recommended hypopnoea criteria increases the number of positional therapy candidates. Sleep and Breathing First Online: 11 November 2016: 1-7. 2016

Halonen KS, Mononen ME, Töyräs J, Kröger H, Joukainen A, Korhonen RK. 2016. Optimal graft stiffness and pre-strain restore normal joint motion and cartilage responses in ACL reconstructed knee. JOURNAL OF BIOMECHANICS 49 13: 2566-2576. 2016

Honkanen Juuso TJ, Mikael J, Freedman Jonathan D, Saarakkala Simo, Grinstaff Mark W, Ylärinne Janne H, Jurvelin Jukka S, Töyräs Juha. 2016. Cationic Contrast Agent Diffusion Differs Between Cartilage and Meniscus. ANNALS OF BIOMEDICAL ENGINEERING 44 10: 2913-2921. 2016

Huttunen JMJ, Turunen MJ, Honkanen JTJ, Töyräs J, Jurvelin JS. 2016. Estimation of Systematic and Spatially Correlated Components of Random Signals from Repeated Measurements: Application to Contrast Enhanced Computer Tomography Measurements. SIAM JOURNAL ON SCIENTIFIC COMPUTING 38 1: B77-B99. 2016

Inkinen SI, Liukkonen J, Malo MK, Virén T, Jurvelin JS, Töyräs J. 2016. Finite difference time domain model of ultrasound propagation in agarose scaffold containing collagen or chondrocytes. The Journal of the Acoustical Society of America 140 1: 1. 2016

Kokkonen HT, Chin HC, Töyräs J, Jurvelin JS, Quinn TM. 2016. Solute transport of negatively charged contrast agents across articular surface of injured cartilage. ANNALS OF BIOMEDICAL ENGINEERING First Online: 08 November 2016: 1-9. 2016

Leppänen Timo, Kulkas Antti, Duce Brett, Mervaala Esa, Töyräs Juha. 2016. Severity of individual obstruction events is gender dependent in sleep apnea. Sleep and Breathing First Online: 13 December 2016: 1-8. 2016

Lasanen R, Piippo-Savolainen E, Remes-Pakarinen T, Kröger L, Heikkilä A., Julkunen P., Karhu J, Töyräs J. 2015. Thermal imaging in screening of joint inflammation and rheumatoid arthritis in children. PHYSIOLOGICAL MEASUREMENT 36 2: 273-282. 2015

Turunen Mikael J, Töyräs Juha, Kokkonen Harri T, Jurvelin Jukka S. 2015. Quantitative evaluation of knee subchondral bone mineral density using cone beam computed tomography. IEEE TRANSACTIONS ON MEDICAL IMAGING 34 10: 2186-2190. 2015

Puhakka PH, Te Moller NC, Afara IO, Mäkelä JT, Tiitu V, Korhonen RK, Brommer H, Virén T, Jurvelin JS, Töyräs J. 2015. Estimation of articular cartilage properties using multivariate analysis of optical coherence tomography signal. OSTEOARTHRITIS AND CARTILAGE 23 12: 2206-2213. 2015

Puhakka Jani, Afara Isaac O, Paatela Teemu, Sormaala Markus J, Timonen Matti A, Virén Tuomas, Jurvelin Jukka S, Töyräs Juha, Kiviranta Ilkka. 2015. In Vivo Evaluation of the Potential of High-Frequency Ultrasound for Arthroscopic Examination of the Shoulder Joint. Cartilage 2016; 7 3: 248-255. 2015

Penttilä Pekko, Liukkonen Jukka, Joukainen Antti, Virén Tuomas, Jurvelin Jukka S, Töyräs Juha, Kröger Heikki. 2015. Diagnosis of Knee Osteochondral Lesions With Ultrasound Imaging. Arthroscopy Techniques 4 5: e429-e433. 2015

Myllymaa Sami, Myllymaa Katja, Kupari Salla, Kulkas Antti, Leppänen Timo, Tiihonen Pekka, Mervaala Esa, Seppä Juha, Tuomilehto Henri, Töyräs Juha. 2015. Effect of different oxygen desaturation threshold levels on hypopnea scoring and classification of severity of sleep apnea. Sleep and Breathing 19 3: 947-954. 2015

Myllymaa Katja, Myllymaa Sami, Leppänen Timo, Kulkas Antti, Kupari Salla, Tiihonen Pekka, Mervaala Esa, Seppä Juha, Tuomilehto Henri, Töyräs Juha. 2015. Effect of oxygen desaturation threshold on determination of OSA severity during weight loss. Sleep and Breathing 2016; 20 1: 33-42. 2015

Muraja-Murro Anu, Mervaala Esa, Westeren-Punnonen Susanna, Lepola Pasi, Töyräs Juha, Myllymaa Sami, Julkunen Petro, Kantanen Anne-Mari, Kälviäinen Reetta, Myllymaa Katja. 2015. Forehead EEG electrode set versus full-head scalp EEG in 100 patients with altered mental state. EPILEPSY & BEHAVIOR 49: 245-249. 2015

Muhonen Virpi, Salonius Eve, Haaparanta Anne-Marie, Järvinen Elina, Paatela Teemu, Meller Anna, Hannula Markus, Björkman Mimmi, Pyhältö Tuomo, Ellä Ville, Vasara Anna, Töyräs Juha, Kellomäki Minna, Kiviranta Ilkka. 2015. Articular cartilage repair with recombinant human type II collagen/polylactide scaffold in a preliminary porcine study. JOURNAL OF ORTHOPAEDIC RESEARCH 2016; 34 5: 745-753. 2015

Lepola Pasi, Myllymaa Sami, Töyräs Juha, Hukkanen Taina, Mervaala Esa, Määttä Sara, Lappalainen Reijo Myllymaa Katja. 2015. A Handy EEG Electrode Set for patients suffering from altered mental state. JOURNAL OF CLINICAL MONITORING AND COMPUTING 29 6: 697-705. 2015

Inkinen Satu I, Liukkonen Jukka, Tiitu Virpi, Viren Tuomas, Jurvelin Jukka S, Töyräs Juha. 2015. Ultrasound Backscattering Is Anisotropic in Bovine Articular Cartilage. ULTRASOUND IN MEDICINE AND BIOLOGY 41 7: 1958-1966. 2015

Lasanen R, Julkunen P, Airaksinen O, Töyräs J. 2015. Menthol concentration in topical cold gel does not have significant effect on skin cooling. SKIN RESEARCH AND TECHNOLOGY 2016; 22 1: 40-45. 2015

Eneh Chibuzor TM, Liukkonen Jukka, Malo Markus KH, Jurvelin Jukka S, Töyräs Juha. 2015. Inter-individual changes in cortical bone three-dimensional microstructure and elastic coefficient have opposite effects on radial sound speed. The Journal of the Acoustical Society of America 138 6: 3491. 2015

Afara Isaac O, Hauta-Kasari Markku, Jurvelin Jukka S, Oloyede Adekunle, Töyräs Juha. 2015. Optical absorption spectra of human articular cartilage correlate with biomechanical properties, histological score and biochemical composition. PHYSIOLOGICAL MEASUREMENT 36 9: 1913-1928. 2015

Kulkas A, Leppänen T, Sahlman J, Tiihonen P, Mervaala E, Kokkarinen J, Randell J, Seppä J, Töyräs J, Tuomilehto H. 2015. Amount of weight loss or gain influences the severity of respiratory events in sleep apnea. MEDICAL AND BIOLOGICAL ENGINEERING AND COMPUTING epub 17 Apr 2015: 14 p. 2015

Danso EK, Mäkelä JTA, Tanska P, Mononen ME, Honkanen JTJ, Jurvelin JS, Töyräs J, Julkunen P, Korhonen RK. 2015. Characterization of site-specific biomechanical properties of human meniscus-Importance of collagen and fluid on mechanical nonlinearities. JOURNAL OF BIOMECHANICS 48 8: 1499-1507. 2015

Ala-Myllymäki Juho, Honkanen Juuso TJ, Töyräs Juha, Afara Isaac O. 2015. Optical spectroscopic determination of human meniscus composition. JOURNAL OF ORTHOPAEDIC RESEARCH 2016; 34 2: 270-278. 2015

Hirvasniemi J., Kokkonen H. T., Thevenot J., Finnilä M., Venäläinen M. S., Jämsä T., Korhonen R. K., Töyräs J., Saarakkala S.. 2015. Comparison of subchondral bone density and structure of tibia measured from plain radiograph with micro-computed tomography. OSTEOARTHRITIS AND CARTILAGE 23: A234-A235. 2015

Hirvasniemi Jukka, Thevenot Jérôme, Kokkonen Harri T, Finnilä Mikko A, Venäläinen Mikko S, Jämsä Timo, Korhonen Rami K, Töyräs Juha, Saarakkala Simo. 2015. Correlation of Subchondral Bone Density and Structure from Plain Radiographs with Micro Computed Tomography Ex Vivo. ANNALS OF BIOMEDICAL ENGINEERING 44: 1698. 2015

Honkanen JTJ, Danso EK, Suomalainen JS, Tiitu V, Korhonen RK, Jurvelin JS, Töyräs J. 2015. Contrast Enhanced Imaging of Human Meniscus Using Cone Beam CT. OSTEOARTHRITIS AND CARTILAGE 23 8: 1367-1376. 2015

Honkanen Juuso, Turunen Mikael, Tiitu Virpi, Jurvelin Jukka, Töyräs Juha. 2015. Transport of Iodine Is Different in Cartilage and Meniscus. ANNALS OF BIOMEDICAL ENGINEERING 2016; 44 7: 2114-2122. 2015

Karjalainen JP, Riekkinen O, Töyräs J, Jurvelin JS, Kröger H. 2015. New method for point-of-care osteoporosis screening and diagnostics. OSTEOPOROSIS INTERNATIONAL 2016; 27 3: 971-977. 2015

Venäläinen Mikko S, Mononen Mika E, Jurvelin Jukka S, Töyräs Juha, Virén Tuomas, Korhonen Rami K. 2014. Importance of Material Properties and Porosity of Bone on Mechanical Response of Articular Cartilage in Human Knee Joint - A Two-Dimensional Finite Element Study. JOURNAL OF BIOMECHANICAL ENGINEERING 136 12: 121005. 2014

Qu Chengjuan, Hirviniemi Mikko, Tiitu Virpi, Jurvelin Jukka S, Töyräs Juha, Lammi Mikko J. 2014. Effects of freeze-thaw cycle with and without proteolysis inhibitors and cryopreservant on the biochemical and biomechanical properties of articular cartilage. Cartilage 5 2: 97-106. 2014

Puhakka PH, Ylärinne JH, Lammi MJ, Saarakkala S, Tiitu V, Kröger H, Virén T, Jurvelin JS, Töyräs J. 2014. Dependence of light attenuation and backscattering on collagen concentration and chondrocyte density in agarose scaffolds. PHYSICS IN MEDICINE AND BIOLOGY 59 21: 6537-48. 2014

Ojanen X, Isaksson H, Töyräs J, Turunen MJ, Malo MKH, Halvari A, Jurvelin JS. 2014. Relationships Between Tissue Composition and Viscoelastic Properties in Human Trabecular Bone. JOURNAL OF BIOMECHANICS Epub 2014 Dec 3: 269-275. 2014

Niemelä Tytti, Virén Tuomas, Liukkonen Jukka, Argüelles David, te Moller Nikae CR, Puhakka Pia H, Jurvelin Jukka S, Tulamo Riitta-Mari, Töyräs Juha. 2014. Application of optical coherence tomography enhances reproducibility of arthroscopic evaluation of equine joints. ACTA VETERINARIA SCANDINAVICA 56 3: -. 2014

Muraja-Murro A, Kulkas A, Hiltunen M, Kupari S, Hukkanen T, Tiihonen P, Mervaala E, Töyräs J. 2014. Adjustment of apnea-hypopnea index with severity of obstruction events enhances detection of sleep apnea patients with the highest risk of severe health consequences. Sleep and Breathing 18 3: 641-647. 2014

Malo MKH, Töyräs J, Karjalainen JP, Isaksson H, Riekkinen O, Jurvelin JS. 2014. Ultrasound backscatter measurements of intact human proximal femurs - Relationships of ultrasound parameters with tissue structure and mineral density. BONE 64: 240-245. 2014

Liukkonen Jukka, Lehenkari Petri, Hirvasniemi Jukka, Joukainen Antti, Virén Tuomas, Saarakkala Simo, Nieminen Miika T, Jurvelin Jukka S, Töyräs Juha. 2014. Ultrasound Arthroscopy of Human Knee Cartilage and Subchondral Bone in Vivo. ULTRASOUND IN MEDICINE AND BIOLOGY 40 9: 2039-2047. 2014

Lepola Pasi, Myllymaa Sami, Töyräs Juha, Muraja-Murro Anu, Mervaala Esa, Lappalainen Reijo, Myllymaa Katja. 2014. Screen-printed EEG electrode set for emergency use. SENSORS AND ACTUATORS A. PHYSICAL 213 July: 19-26. 2014

Huttunen JMJ, Kokkonen HT, Jurvelin JS, Töyräs J, Kaipio JP. 2014. Estimation of fixed charge density and diffusivity profiles in cartilage using contrast enhanced computer tomography. INTERNATIONAL JOURNAL FOR NUMERICAL METHODS IN ENGINEERING 98 5: 371-390. 2014

Halonen KS, Mononen ME, Jurvelin JS, Töyräs J, Salo J, Korhonen RK. 2014. Deformation of articular cartilage during static loading of a knee joint - Experimental and finite element analysis. JOURNAL OF BIOMECHANICS 47 10: 2467-2474. 2014

Husso M, Sipola P, Kuittinen T, Manninen H, Vainio P, Hartikainen J, Saarakkala S, Töyräs J, Kuikka J. 2014. Assessment of myocardial perfusion with MRI using a modified dual bolus method. PHYSIOLOGICAL MEASUREMENT 35 4: 533-47. 2014

Lepola Pasi, Myllymaa Sami, Töyräs Juha, Mervaala Esa, Lappalainen Reijo, Myllymaa Katja. 2014. Shielded design of screen-printed EEG electrode set reduces interference pick-up. IEEE SENSORS JOURNAL 14 8: 2692-2697. 2014

Inkinen Satu, Liukkonen Jukka, Ylärinne Janne, Puhakka Pia, Lammi Mikko, Virén Tuomas, Jurvelin Jukka, Töyräs Juha. 2014. Collagen and chondrocyte concentrations control ultrasound scattering in agarose scaffolds. ULTRASOUND IN MEDICINE AND BIOLOGY 40 9: 2162-2171. 2014

Kulkas A, Muraja-Murro A, Tiihonen P, Mervaala E, Töyräs J. 2014. Morbidity and mortality risk ratios are elevated in severe supine dominant OSA: a long-term follow-up study. Sleep and Breathing epub: 8 sivua. 2014

Lappalainen R, Mervaala E, Myllymaa K, Myllymaa S, Töyräs J. 2014. Arrangement and method for carrying out electrode measurements. WO 2014072582 A1. 2014

Kulkas A, Leppänen T, Sahlman J, Tiihonen P, Mervaala E, Kokkarinen J, Randell J, Seppä J, Töyräs J, Tuomilehto H. 2014. Weight loss alters severity of individual nocturnal respiratory events depending on sleeping position. PHYSIOLOGICAL MEASUREMENT 35 10: 2037-2052. 2014

Liukkonen J, Lehenkari P, Hirvasniemi J, Joukainen A, Virén T, Saarakkala S, Nieminen M, Jurvelin JS, Töyräs J. 2013. Ultrasound Arthroscopy of Human Knee Joint: Feasibility In Vivo, ESUCB 2013, 5th European Symposium on Ultrasonic Characterization of Bone. 50. 2013

te Moller, NCR; Brommer, H; Liukkonen, J; Virén T; Timonen M; Puhakka PH; Jurvelin JS; van Weeren PR; Töyräs J. 2013. Arthroscopic optical coherence tomography provides detailed information on articular cartilage lesions in horses. The Veterinary Journal 197: 589-595. 2013

Salo J, Töyräs J, Joukainen A, Jurvelin J, Kröger H. 2013. Rustovaurioiden kehittyvä diagnostiikka - nopein hoitotuloksia parantava tekijä?. SUOMEN ORTOPEDIA JA TRAUMATOLOGIA 36 3: 256-261. 2013

Myllymaa Sami, Lepola Pasi, Töyräs Juha, Hukkanen Taina, Mervaala Esa, Lappalainen Reijo, Myllymaa Katja. 2013. New disposable forehead electrode set with excellent signal quality and imaging compatibility. JOURNAL OF NEUROSCIENCE METHODS 215 1: 103-109. 2013

Myllymaa S, Lepola P, Hukkanen T, Oun A, Mervaala E, Toyras J, Lappalainen R, Myllymaa K. 2013. Novel screen printed electrode set for routine EEG recordings in patients with altered mental status: -, Engineering in Medicine and Biology Society (EMBC), 2013 35th Annual International Conference of the IEEE. Engineering in Medicine and Biology Society Proceedings. 6724-6727. 2013

Muraja-Murro A, Kulkas A, Hiltunen M, Kupari S, Hukkanen T, Tiihonen P, Mervaala E, Töyräs J. 2013. The severity of individual obstruction events is related to increased mortality rate in severe obstructive sleep apnea. Journal of Sleep Research 22 6: 663-669. 2013

Muraja-Murro A, Eskola K, Kolari T, Tiihonen P, Hukkanen T, Tuomilehto H, Peltonen M, Mervaala E, Töyräs J. 2013. Mortality in middle-aged men with obstructive sleep apnea in Finland. Sleep and Breathing 17 3: 1047-1053. 2013

Malo MK, Rohrbach D, Isaksson H, Töyräs J, Jurvelin JS, Tamminen IS, Kröger H, Raum K. 2013. Longitudinal elastic properties and porosity of cortical bone tissue vary with age in human proximal femur. BONE 53 2: 451-458. 2013

Liukkonen J, Lehenkari P, Hirvasniemi J, Joukainen A, Saarakkala S, Jurvelin J, Töyräs J. 2013. Ultrasound Arthroscopy of Human Knee Joint in vivo,, ORS 2013 annual meeting. 1986. 2013

Liukkonen J, Hirvasniemi J, Joukainen A, Penttilä P, Virén T, Saarakkala S, Kröger H, Jurvelin JS, Töyräs J. 2013. Arthroscopic ultrasound technique for simultaneous quantitative assessment of articular cartilage and subchondral bone: an in vitro and in vivo feasibility study. ULTRASOUND IN MEDICINE AND BIOLOGY 39 8: 1460-1468. 2013

Kulmala KAM, Karjalainen HM, Kokkonen HT, Tiitu V, Kovanen V, Lammi MJ, Jurvelin JS, Korhonen RK, Töyräs J. 2013. Diffusion of ionic and non-ionic contrast agents in articular cartilage with increased cross-linking-contribution of steric and electrostatic effects. MEDICAL ENGINEERING & PHYSICS 35 10: 1415-1420. 2013

Kulkas A, Tiihonen P, Julkunen P, Mervaala E, Töyräs J. 2013. Novel parameters indicate significant differences in severity of obstructive sleep apnea with patients having similar apnea-hypopnea index. MEDICAL AND BIOLOGICAL ENGINEERING AND COMPUTING 51 6: 697-708. 2013

Kulkas A, Tiihonen P, Julkunen P, Mervaala E, Töyräs J. 2013. Desaturation delay, parameter for evaluating severity of sleep disordered breathing: Long M, World Congress on Medical Physics and Biomedical Engineering May 26-31, 2012, Beijing, China. IFMBE Proceedings 39. 336-339. 2013

Kulkas A, Tiihonen P, Eskola K, Julkunen P, Mervaala E, Töyräs J. 2013. Novel parameters for evaluating severity of sleep disordered breathing and for supporting diagnosis of sleep apnea-hypopnea syndrome. JOURNAL OF MEDICAL ENGINEERING & TECHNOLOGY 37 2: 135-143. 2013

Kulkas A, Leppänen T, Sahlman J, Tiihonen P, Mervaala E, Kokkarinen J, Randell J, Seppä J, Tuomilehto H, Töyräs J. 2013. Novel parameters reflect changes in morphology of respiratory events during weight loss. PHYSIOLOGICAL MEASUREMENT 34 9: 1013-1026. 2013

Kokkonen HT, Suomalainen JS, Joukainen A, Kröger H, Sirola J, Jurvelin JS, Salo J, Töyräs J. 2013. In vivo diagnostics of human knee cartilage lesions using delayed CBCT arthrography. JOURNAL OF ORTHOPAEDIC RESEARCH 2013 2014 Mar;32(3):403-12: 1-10. 2013

Inkinen, S; Liukkonen, J; Ylärinne, Puhakka, PH; J; Lammi, M; Virén, T; Jurvelin JS; Töyräs, J. 2013. Collagen and Chondrocyte Content Control Ultrasound Scattering in Agarose Scaffolds, ORS 2013 annual meeting. 1214. 2013

Halonen KS, Mononen ME, Jurvelin JS, Töyräs J, Korhonen RK. 2013. Importance of depth-wise distribution of collagen and proteoglycans in articular cartilage - A 3D finite element study of stresses and strains in human knee joint. JOURNAL OF BIOMECHANICS 46 6: 1184-1192. 2013

Muraja-Murro A, Nurkkala J, Tiihonen P, Hukkanen T, Tuomilehto H, Kokkarinen J, Mervaala E, Töyräs J. 2012. Total duration of apnea and hypopnea events and average desaturation show significant variation in patients with a similar apnea-hypopnea index. JOURNAL OF MEDICAL ENGINEERING & TECHNOLOGY 36 8: 393-398. 2012

Virén T, Timonen M, Tyrväinen H, Tiitu V, Jurvelin JS, Töyräs J. 2012. Ultrasonic evaluation of acute impact injury of articular cartilage in vitro OSTEOARTHRITIS AND CARTILAGE 20: 719-726. 2012

Silvast Tuomo, Jurvelin Jukka, Tiitu Virpi, Quinn Thomas, Töyräs Juha. 2012. Bath concentration of anionic contrast agents does not affect their diffusion and distribution in articular cartilage in vitro Cartilage 2013; 4 1: 42-51. 2012

Pulkkinen HJ, Tiitu V, Valonen P, Jurvelin JS, Rieppo L, Töyräs J, Silvast TS, Lammi MJ, Kiviranta I. 2012. Repair of osteochondral defects with recombinant human type II collagen gel and autologous chondrocytes in rabbit. OSTEOARTHRITIS AND CARTILAGE 2012 Dec 17. pii: S1063-4584(12)01049-7.: --. 2012

Virén T, Huang YP, Saarakkala S, Pulkkinen H, Tiitu V, Linjama A, Kiviranta I, Lammi MJ, Brünott A, Van Weeren R, Brama PAJ, Zheng YP, Jurvelin JS, Töyräs J. 2012. Comparison of ultrasound and optical coherence tomography techniques for evaluation of integrity of spontaneously repaired horse cartilage. JOURNAL OF MEDICAL ENGINEERING & TECHNOLOGY 36 3: 185-192. 2012

Liukkonen J, Hirvasniemi J, Joukainen A, Penttilä P, Virén T, Jurvelin, JS, Töyräs, J. 2012. Simultaneous quantitative ultrasound assessment of cartilage and subchondral bone, ORS 2012 annual meeting, Orthpaedic Research Society. 1443. 2012

K.A.M. Kulmala, H.J. Pulkkinen, L. Rieppo, V. Tiitu, I. Kiviranta, A. Brünott, H. Brommer, R. van Weeren, P.A.J. Brama, M.T. Mikkola, R.K. Korhonen, J.S. Jurvelin, J.Töyräs. 2012. Contrast-Enhanced Micro-Computed Tomography in Evaluation of Spontaneous Repair of Equine Cartilage. Cartilage 3 3: 235-244. 2012

Kokkonen, Harri; Aula, Antti; Kröger, Heikki; Suomalainen, Juha-Sampo; Lammentausta, Eveliina; Mervaala, Esa; Jurvelin, Jukka; Töyräs, Juha. 2012. Delayed computed tomography artrography of human knee cartilage In Vivo. Cartilage 3 4: 334-341. 2012

Hirvasniemi J, Kulmala KAM, Lammentausta E, Ojala R, Lehenkari P, Kamel A, Jurvelin JS, Töyräs J, Nieminen MT and Saarakkala S. 2012. In vivo comparison of delayed gadolinium-enhanced MRI of cartilage and delayed quantitative CT arthrography in imaging of articular cartilage. OSTEOARTHRITIS AND CARTILAGE xx xx: xx. 2012

Salo E-N, Nissi MJ, Kulmala KAM, Tiitu V, Töyräs J, Nieminen MT. 2012. Diffusion of Gd-DTPA2- into articular cartilage. OSTEOARTHRITIS AND CARTILAGE 20 2: 117-126. 2012

Karjalainen JP., Riekkinen O., Töyräs J., Hakulinen M., Kröger H., Rikkonen T., Salovaara K., Jurvelin JS.. 2012. Multi-site bone ultrasound measurements in elderly women with and without previous hip fractures OSTEOPOROSIS INTERNATIONAL 23: 1287-1295. 2012

Kinnunen Jussi, Kokkonen Harri T, Kovanen Vuokko, Hauta-Kasari Markku, Vahimaa Pasi, Lammi Mikko J, Töyräs Juha, Jurvelin Jukka S. 2012. Nondestructive fluorescence-based quantification of threose-induced collagen cross-linking in bovine articular cartilage. Journal of Biomedical Optics 17 9: 97003. 2012

Liukkonen J, Aula A, Töyräs J, Jurvelin JS. 2011. Simultaneous quantitative ultrasound assessment of cartilage and subchondral bone, 4th European Symposium on Ultrasonic Characterization of Bone (ESUCB). 76. 2011

Turunen MJ, Töyräs J, Lammi MJ, Jurvelin JS, Korhonen RK. 2011. Hyperosmolaric Contrast Agents in Cartilage Tomography May Expose Cartilage to Overload- Induced Cell Death. JOURNAL OF BIOMECHANICS 45: 497-503. 2011

Salo J, Kokkonen HT, Kröger H, Jurvelin JS, Töyräs J. 2011. Kartiokeila-TT kokeellisen rustovaurion diagnostiikassa SUOMEN ORTOPEDIA JA TRAUMATOLOGIA 34 3: 288-289. 2011

Penttilä P, Liukkonen J, Joukainen A, Virén T, Jurvelin JS, Kröger H, Töyräs J. 2011. Evaluation of Joint Cartilage and Subchondral Bone using Arthroscopic Ultrasound Imaging SUOMEN ORTOPEDIA JA TRAUMATOLOGIA 34 3: 229. 2011

Mononen ME, Julkunen P, Toyras J, Jurvelin JS, Kiviranta I, Korhonen RK. 2011. Alterations in structure and properties of collagen network of osteoarthritic and repaired cartilage modify knee joint stresses BIOMECHANICS AND MODELING IN MECHANOBIOLOGY 10 3: 357-369. 2011

Malo MK, Karjalainen JP, Riekkinen O, Isaksson H, Jurvelin JS, Töyräs J.. 2011. Effects of non-optimal focusing on dual-frequency ultrasound measurements of bone IEEE TRANSACTIONS ON ULTRASONICS, FERROELECTRICS, AND FREQUENCY CONTROL 58 6: 1182-1188. 2011

Virén Tuomas, Saarakkala Simo, Tiitu Virpi, Puhakka Jani, Kiviranta Ilkka, Jurvelin Jukka S, Töyräs Juha. 2011. Ultrasound evaluation of mechanical injury of bovine knee articular cartilage under arthroscopic control IEEE TRANSACTIONS ON ULTRASONICS, FERROELECTRICS, AND FREQUENCY CONTROL 58 1: 148-154. 2011

Kulmala K.A.M, Pulkkinen H.J, Rieppo L, Tiitu V, Kiviranta I, Brünott A, Brommer H, van Weeren R, Brama P.A.J, Mikkola M.T, Korhonen R.K, Jurvelin J.S, Töyräs J.. 2011. Contrast enhanced computed tomography in evaluation of spontaneous cartilage repair. Teoksessa: (toim.), 5th Osteoarthritis Imaging Workshop. ss. 6. 2011

Isaksson, Hanna; Töyräs, J; Hakulinen, M; Aula, AS; Tamminen, Inari; Julkunen, P; Kröger, Heikki; Jurvelin, Jukka. 2011. Structural parameters of normal and osteoporotic human trabecular bone are affected differently by microCT image resolution. OSTEOPOROSIS INTERNATIONAL 22 1: 167-177. 2011

Kokkonen HT, Mäkelä J, Kulmala KAM, Rieppo L, Jurvelin JS, Tiitu V, Karjalainen HM, Korhonen RK, Kovanen V, Töyräs J. 2011. Computed tomography detects changes in contrast agent diffusion after collagen cross-linking typical to natural aging of articular cartilage OSTEOARTHRITIS AND CARTILAGE 19: 1190-1198. 2011

Huang YP, Saarakkala S, Töyräs J, Wang LK, Jurvelin JS, Zheng YP.. 2011. Effects of optical beam angle on quantitative optical coherence tomography (OCT) in normal and surface degenerated bovine articular cartilage. PHYSICS IN MEDICINE AND BIOLOGY 56 2: 491-509. 2011

Timonen MA, Töyräs J, Aula AS, Karjalainen JP, Riekkinen O, Jurvelin JS. 2011. Technical and practical improvements in arthroscopic indentation technique for diagnostics of articular cartilage softening JOURNAL OF MEDICAL ENGINEERING & TECHNOLOGY 35 1: 40-46. 2011

Kaleva Erna, Viren Tuomas, Saarakkala Simo, Sahlman Janne, Sirola Joonas, Puhakka Jani, Paatela Teemu, Kröger Heikki, Kiviranta Ilkka, Jurvelin Jukka, Töyräs Juha. 2011. Arthroscopic Ultrasound Assessment of Articular Cartilage in the Human Knee Joint Cartilage 2 3: 246-253. 2011

Kokkonen HT, Jurvelin JS, Tiitu V, Töyräs J. 2011. Detection of mechanical injury of articular cartilage using contrast enhanced computed tomography OSTEOARTHRITIS AND CARTILAGE 19: 297-301. 2011

Kinnunen Jussi, Hauta-Kasari Markku, Kokkonen Harri, Vahimaa Pasi, Lammi Mikko, Töyräs Juha, Jurvelin Jukka. 2011. Collagen cross-link modified fluorescence excitation-emission matrix of articular cartilage: N/A, Topical problems of biophotonics -2011, proceedings. 59-60. 2011

Salo, E-N., Nissi, M. J., Kulmala K. A., Töyräs J., Nieminen M. T.. 2010. Dynamics of contrast agent enhancement of intact and enzymatically degraded articular cartilage, Proceedings of the International Society of Magnetic Resonance in Medicine 18. 3177. 2010

Salo, E-N., Nissi, M. J., Kulmala K. A., Töyräs J., Nieminen M. T.. 2010. Diffusivity and kinetics of gadopentetate in articular cartilage in vitro. Teoksessa: (toim.), Proceedings of the International Society of Magnetic Resonance in Medicine 18. ss. 234. 2010

Mononen, M E; Julkunen, P; Jurvelin, J S; Töyräs, J; Korhonen, R K. 2010. Effect of Degenerative Changes of Articular Cartilage on Knee Joint Stresses ¿ Functional Imaging by Combining Clinical MRI and Finite Element Modeling. Teoksessa: Smith & Nephew, Inc. (toim.), Transactions of the Orthopaedic Research Society. ss. 865. 2010

Salo E-N., Nissi M. J., Kulmala K., Töyräs J., Nieminen M. T.. 2010. Temporal dynamics and diffusion of gadopentetate in articular cartilage at MRI concentrations in vitro, Transactions of the Orthopaedic Research Society 35. 1348. 2010

Kulmala K.A.M.,Korhonen R.K.,Julkunen P,Jurvelin J.S.,Quinn T.M.,Kröger H,Töyräs J. 2010. Diffusion coefficients of articular cartilage for different CT and MRI contrast agents MEDICAL ENGINEERING & PHYSICS 32: 878-882. 2010

Kaleva E., Liukkonen J, Töyräs J, Saarakkala S, Kiviranta P, and Jurvelin JS. 2010. 2-D Finite Difference Time Domain Model of Ultrasound Reflection From Normal and Osteoarthritic Human Articular Cartilage Surface. IEEE TRANSACTIONS ON ULTRASONICS, FERROELECTRICS, AND FREQUENCY CONTROL 57 4: 892-9. 2010

Bone Quantitative Ultrasound. Laugier P. and Haiat G.. 2010 2010

Aula AS, Töyräs J, Tiitu V, Jurvelin JS. 2010. Simultaneous ultrasound measurement of articular cartilage and subchondral bone. OSTEOARTHRITIS AND CARTILAGE 18 12: 1570-1576. 2010

Kulmala KAM, Korhonen RK, Julkunen P, Jurvelin JS, Quinn TM, Kröger H, Töyräs J. 2010. Diffusion of CT and MRI contrast agents in articular cartilage in vitro. Teoksessa: (toim.), Transactions of the Orthopaedic Research Society. ss. 1352. 2010

Myllymaa S, Myllymaa K, Korhonen H, Töyräs J, Jääskeläinen JE, Djupsund K, Tanila H, Lappalainen R. 2009. Fabrication and testing of polyimide-based microelectrode arrays for cortical mapping of evoked potentials BIOSENSORS AND BIOELECTRONICS 24: 3067-3072. 2009

Viren T, Saarakkala S, Kaleva E, Nieminen HJ, Jurvelin JS, Töyräs J. 2009. Minimally invasive ultrasound method for intra-articular diagnostics of cartilage degeneration. ULTRASOUND IN MEDICINE AND BIOLOGY 35 9: 1546-1554. 2009

Tiihonen P, Pääkkönen A, Mervaala E, Hukkanen T, Töyräs J. 2009. Design, construction and evaluation of an ambulatory device for screening of sleep apnea. MEDICAL AND BIOLOGICAL ENGINEERING AND COMPUTING 47: 59-66. 2009

Tiihonen P, Hukkanen T, Tuomilehto H, Mervaala E, Töyräs J. 2009. Evaluation of a novel ambulatory device for screening of sleep apnea. TELEMEDICINE JOURNAL AND E-HEALTH 15 3: 283-289. 2009

Tiihonen P, Hukkanen T, Tuomilehto H, Mervaala E, Pääkkönen A, Töyräs J. 2009. Accuracy of automatic analysis of ambulatory recordings of nocturnal breathing disorders is significantly instrumentation dependent. JOURNAL OF MEDICAL ENGINEERING & TECHNOLOGY 33 5: 386-393. 2009

Silvast TS, Kokkonen HT, Jurvelin JS, Quinn TM, Nieminen MT, Töyräs J. 2009. Diffusion and near-equilibrium distribution of MRI and CT contrast agents in articular cartilage. PHYSICS IN MEDICINE AND BIOLOGY 54: 6823-6836. 2009

Silvast TS, Jurvelin JS, Lammi MJ, Töyräs J. 2009. pQCT study on diffusion and equilibrium distribution of iodinated anionic contrast agent in human articular cartilage - associations to matrix composition and integrity. OSTEOARTHRITIS AND CARTILAGE 17: 26-32. 2009

Silvast TS, Jurvelin JS, Aula AS, Lammi MJ, Töyräs J. 2009. Contrast agent-enhanced computed tomography of articular cartilage: association with tissue composition and properties ACTA RADIOLOGICA 50 1: 78-85. 2009

Lötjönen P, Julkunen P, Töyräs J, Lammi MJ, Jurvelin JS, Nieminen HJ. 2009. Strain-dependent modulation of ultrasound speed in articular cartilage under dynamic compression. ULTRASOUND IN MEDICINE AND BIOLOGY 35 7: 1177-1184. 2009

Karjalainen JP, Töyräs J, Riekkinen O, Hakulinen M, Jurvelin JS. 2009. Ultrasound backscatter imaging provides frequency-dependent information on structure, composition and mechanical properties of human trabecular bone ULTRASOUND IN MEDICINE AND BIOLOGY 35 8: 1376-1384. 2009

Karjalainen J, Töyräs J, Riekkinen O, Hakulinen MA. 2009. Ultrasound backscattering outperforms the clinically used ultrasound parameters in discrimination of osteoporotic-like human trabecular bone samples: Dössel O, Schlegel WC, World Congress on Medical Physics and Biomedical Engineering. Diagnostic Imaging. IFMBE Proceedings.Springer. 94-97. 2009

Kaleva E, Töyräs J, Jurvelin JS, Viren T, Saarakkala S. 2009. Effects of ultrasound frequency, temporal sampling frequency, and spatial sampling step on the quantitative ultrasound parameters of articular cartilage. IEEE TRANSACTIONS ON ULTRASONICS, FERROELECTRICS, AND FREQUENCY CONTROL 56 7: 1383-1393. 2009

Kaleva E, Saarakkala S, Jurvelin JS, Viren T, Töyräs J. 2009. Effects of ultrasound beam angle and surface roughness on the quantitative ultrasound parameters of articular cartilage. ULTRASOUND IN MEDICINE AND BIOLOGY 35 8: 1344-1351. 2009

Aula AS, Töyräs J, Hakulinen MA, Jurvelin JS. 2009. Effect of bone marrow on acoustic properties of trabecular bone - 3D finite difference modelling study. ULTRASOUND IN MEDICINE AND BIOLOGY 35 2: 308-318. 2009

Aula AS, Jurvelin JS, Töyräs J. 2009. Simultaneous computed tomography of articular cartilage and subchondral bone. OSTEOARTHRITIS AND CARTILAGE 17: 1583-1588. 2009

Kiviranta P, Lammentausta E, Töyräs J, Nieminen HJ, Julkunen P, Kiviranta I, Jurvelin JS. 2009. Differences in acoustic properties of intact and degenerated human patellar cartilage during compression ULTRASOUND IN MEDICINE AND BIOLOGY 35 8: 1367-1375. 2009

Karjalainen JP., Riekkinen O., Töyräs J., Jurvelin JS., Kröger H.. 2008. Recent Developments and Future Prospects in Bone Ultrasound Diagnostics European Musculoskeletal Review 3 2: 90-94. 2008

Tiihonen P, Kinnunen J, Töyräs J, Mervaala E, Pääkkönen A. 2008. A portable device for intensive care brain function monitoring with event-related potentials. COMPUTER METHODS AND PROGRAMS IN BIOMEDICINE 89: 83-92. 2008

Riekkinen O, Hakulinen MA, Töyräs J, Jurvelin JS. 2008. Dual-frequency ultrasound - new pulse-echo technique for bone densitometry. ULTRASOUND IN MEDICINE AND BIOLOGY 34 10: 1703-1708. 2008

Kiviranta P, Lammentausta E, Töyräs J, Kiviranta I, Jurvelin JS. 2008. Indentation diagnostics of cartilage degeneration. OSTEOARTHRITIS AND CARTILAGE 16: 796-804. 2008

Kurkijärvi JE, Nissi MJ, Rieppo J, Töyräs J, Kiviranta I, Nieminen MT, Jurvelin JS. 2008. The zonal architecture of human articular cartilage described by T2 relaxation time in the presence of Gd-DTPA2-. MAGNETIC RESONANCE IMAGING 26: 602-607. 2008

Karjalainen J, Töyräs J, Rikkonen T, Jurvelin JS, Riekkinen O. 2008. Dual-frequency ultrasound technique minimizes errors induced by soft tissue in ultrasound bone densitometry. ACTA RADIOLOGICA 49 9: 1038-1041. 2008

Karjalainen J, Riekkinen O, Töyräs J, Jurvelin J, Kröger H. 2008. Recent developments and future prospects in bone ultrasound diagnostics, European Musculoskeletal Review [Online].Touch Briefings. 87-89. 2008

Janne Karjalainen, Juha Töyräs, Toni Rikkonen, Jukka Jurvelin, Ossi Riekkinen. 2008. Dual frequency ultrasound technique minimizes errors induced by soft tissues in ultrasound bone densitometry ACTA RADIOLOGICA 49: 1038-41. 2008

Kaleva E, Saarakkala S, Töyräs J, Nieminen HJ, Jurvelin JS. 2008. In-vitro comparison of time-domain, frequency-domain and wavelet ultrasound parameters in diagnostics of cartilage degeneration. ULTRASOUND IN MEDICINE AND BIOLOGY 34: 155-159. 2008

Jurvelin JS, Nieminen MT, Töyräs J, Risteli J, Laasanen MS, Konttinen YT, Kiviranta I. 2008. Fysikaaliset ja kemialliset menetelmät nivelrikon varhaisessa osoittamisessa. DUODECIM 124: 1885-1896. 2008

Karjalainen J, Riekkinen O, Töyräs J, Kröger H, Jurvelin J. 2008. Ultrasonic assessment of cortical bone thickness In Vitro and In Vivo IEEE TRANSACTIONS ON ULTRASONICS, FERROELECTRICS, AND FREQUENCY CONTROL 55 10: 2191-2197. 2008

Riekkinen O, Hakulinen MA, Lammi MJ, Jurvelin JS, Kallioniemi A, Töyräs J. 2007. Acoustic properties of trabecular bone-relationships to tissue composition. ULTRASOUND IN MEDICINE AND BIOLOGY 33 9: 1438-1444. 2007

Sierpowska J, Lammi MJ, Hakulinen MA, Jurvelin JS, Lappalainen R, Töyräs J. 2007. Effect of human trabecular bone composition on its electrical properties MEDICAL ENGINEERING & PHYSICS 29 8: 845-852. 2007

Saarakkala S, Jurvelin JS, Zheng YP, Nieminen HJ, Töyräs J. 2007. Quantitative information from ultrasound evaluation of articular cartilage should be interpreted with care. ARTHROSCOPY 23 10: 1137-1141. 2007

Riekkinen O, Hakulinen MA, Töyräs J, Jurvelin JS. 2007. Spatial variation of acoustic properties is related with mechanical properties of trabecular bone. PHYSICS IN MEDICINE AND BIOLOGY 52: 6961-6968. 2007

Nieminen HJ, Julkunen P, Töyräs J, Jurvelin JS. 2007. Ultrasound speed in articular cartilage under mechanical compression ULTRASOUND IN MEDICINE AND BIOLOGY 33 11: 1755-1766. 2007

Qu CJ, Rieppo J, Hyttinen MM, Lammi MJ, Kiviranta I, Kurkijärvi J, Jurvelin J, Töyräs J. 2007. Human articular cartilage proteoglycans are not undesulfated in osteoarthritis. CONNECTIVE TISSUE RESEARCH 48 1: 27-33. 2007

Nissi MJ, Rieppo J, Töyräs J, Laasanen MS, Kiviranta I, Nieminen MT, Jurvelin JS. 2007. Estimation of mechanical properties of articular cartilage with MRI - dGEMRIC, T2 and T1 imaging in different species with variable stages of maturation OSTEOARTHRITIS AND CARTILAGE 15: 1141-1148. 2007

Lammentausta E, Kiviranta P, Töyräs, Hyttinen MM, Kiviranta I, Nieminen MT, Jurvelin JS. 2007. Quantitative MRI of parallel changes of articular cartilage and underlying trabecular bone in degeneration. OSTEOARTHRITIS AND CARTILAGE 15: 1149-1157. 2007

Kiviranta P, Töyräs J, Nieminen MT, Laasanen MS, Saarakkala S, Nieminen HJ, Nissi MJ, Jurvelin J. 2007. Comparison of novel clinically applicable methodology for sensitive diagnostics of cartilage degeneration. EUROPEAN CELLS AND MATERIALS 13: 46-55. 2007

Kallioniemi AS, Jurvelin JS, Nieminen MT, Lammi MJ, Töyräs J. 2007. Contrast agent enhanced pQCT of articular cartilage. PHYSICS IN MEDICINE AND BIOLOGY 52: 1209-1219. 2007

Nissi MJ, Rieppo J, Töyräs J, Laasanen MS, Kiviranta I, Jurvelin JS, Nieminen MT. 2006. T2 relaxation time mapping reveals age- and species-related diversity of collagen network architecture in articular cartilage. OSTEOARTHRITIS AND CARTILAGE 14: 1265-1271. 2006

Saarakkala S, Laasanen MS, Jurvelin JS, Töyräs J. 2006. Quantitative ultrasound imaging detects degenerative changes in articulas cartilage surface and subchondral bone. PHYSICS IN MEDICINE AND BIOLOGY 51: 5333-5346. 2006

Riekkinen O, Hakulinen MA, Timonen M, Töyräs J, Jurvelin JS. 2006. Influence of overlying soft tissues on trabecular bone acoustic measurement at various ultrasound frequencies ULTRASOUND IN MEDICINE AND BIOLOGY 32 7: 1073-1083. 2006

Sierpowska J, Hakulinen MA, Töyräs J, Day JS, Weinans H, Kiviranta I, Jurvelin JS, Lappalainen R. 2006. Interrelationships between electrical proberties and microstructure of human trabecular bone. PHYSICS IN MEDICINE AND BIOLOGY 51: 5289-5303. 2006

Nieminen HJ, Töyräs J, Laasanen MS, Jurvelin JS. 2006. Acoustic properties articular cartilage under mechanical stress. BIORHEOLOGY 43 3-4: 523-535. 2006

Kopakkala-Tani M, Leskinen JJ, Karjalainen HM, Karjalainen T, Hynynen K, Töyräs J, Jurvelin JS, Lammi MJ. 2006. Ultrasound stimulates proteoglycan synthesis in bovine primary chondrocytes. BIORHEOLOGY 43: 271-282. 2006

Kiviranta P, Rieppo J, Korhonen RK, Julkunen P, Töyräs J, Jurvelin JS. 2006. Collagen network primarily controls Poisson's ratio of bovine articular cartilage in compression JOURNAL OF ORTHOPAEDIC RESEARCH 24 4: 690-699. 2006

Hakulinen MA, Day JS, Töyräs J, Weinans H, Jurvelin JS, Hakulinen MA. 2006. Ultrasonic characterization of human trabecular bone microstructure. PHYSICS IN MEDICINE AND BIOLOGY 51: 1633-1648. 2006

Laasanen MS, Töyräs J, Vasara A, Saarakkala S, Hyttinen MM, Kiviranta I, Jurvelin JS. 2006. Quantitative ultrasound imaging of spontaneous repair of porcine cartilage. OSTEOARTHRITIS AND CARTILAGE 14: 258-263. 2006

Hakulinen MA, Day JS, Töyräs J, Timonen M, Kröger H, Weinans H, Kiviranta I, Jurvelin JS, Kröger H. 2005. Prediction of density and mechanical properties of human trabecular bone in vitro by using ultrasound transmission and backscattering measurements at 0.2-6.7 MHz frequency range. PHYSICS IN MEDICINE AND BIOLOGY 50: 1629-1642. 2005

Laasanen MS, Saarakkala S, Töyräs J, Rieppo J, Jurvelin JS. 2005. Site-specific ultrasound reflection properties and superficial collagen content of bovine knee articular cartilage. PHYSICS IN MEDICINE AND BIOLOGY 50: 3221-3233. 2005

Sierpowska J, Hakulinen MA, Töyräs J, Day JS, Weinans H, Jurvelin JS, Lappalainen R. 2005. Prediction of mechanical properties of human trabecular bone by electrical measurements. PHYSIOLOGICAL MEASUREMENT 26: S119-S131. 2005

Töyräs J, Korhonen RK, Voutilainen T, Jurvelin JS, Lappalainen R. 2005. Improvement of arthroscopic cartilage stiffness probe using amorphous diamond coating. JOURNAL OF BIOMEDICAL MATERIALS RESEARCH B. APPLIED BIOMATERIALS 73B: 15-22. 2005

Nissi MJ, Töyräs J, Laasanen MS, Rieppo J, Saarakkala S, Lappalainen R, Jurvelin JS, Nieminen MT. 2004. Proteoglycan and collagen sensitive MRI evaluation of normal and degenerated articular cartilage. JOURNAL OF ORTHOPAEDIC RESEARCH 22: 557-564. 2004

Saarakkala S, Töyräs J, Hirvonen J, Laasanen MS, Lappalainen R, Jurvelin JS. 2004. Ultrasonic quantitation of superficial degradation of articular cartilage. ULTRASOUND IN MEDICINE AND BIOLOGY 30 6: 783-792. 2004

Saarakkala S, Korhonen RK, Laasanen MS, Töyräs J, Rieppo J, Jurvelin JS. 2004. Mechano-acoustic determination of Young's moduls of articular cartilage BIORHEOLOGY 41: 167-179. 2004

Lammi MJ, Qu C-J, Laasanen MS, Saarakkala S, Rieppo J, Jurvelin JS, Töyräs J. 2004. Undersulfated chondroitin sulfate does not increase in osteoarthritic cartilage. JOURNAL OF RHEUMATOLOGY 31: 2449-2453. 2004

Nieminen MT, Töyräs J, Laasanen MS, Silvennoinen J, Helminen HJ, Jurvelin JS. 2004. Prediction of biomechanical properties of articular cartilage with quantitative magnetic resonance imaging. JOURNAL OF BIOMECHANICS 37: 321-328. 2004

Nieminen HJ, Saarakkala S, Laasanen MS, Hirvonen J, Jurvelin JS, Töyräs J. 2004. Ultrasound attenuation in normal and spontaneously degenerated articular cartilage ULTRASOUND IN MEDICINE AND BIOLOGY 30 4: 493-500. 2004

Hakulinen MA, Töyräs J, Saarakkala S, Hirvonen J, Kröger H, Jurvelin JS, Kröger H. 2004. Ability of ultrasound backscattering to predict mechanical properties of bovine trabecular bone. ULTRASOUND IN MEDICINE AND BIOLOGY 30 7: 919-927. 2004

Töyräs J, Laasanen MS, Saarakkala S, Lammi MJ, Rieppo J, Kurkijärvi J, Lappalainen R, Jurvelin JS. 2003. Speed of sound in normal and degenerated bovine articular cartilage. ULTRASOUND IN MEDICINE AND BIOLOGY 29 3: 447-454. 2003

Sierpowska J, Töyräs J, Hakulinen MA, Saarakkala S, Jurvelin JS, Lappalainen R. 2003. Electrical and dielectric properties of bovine trabecular bone - relationship with mechanical properties and mineral density. PHYSICS IN MEDICINE AND BIOLOGY 48: 775-786. 2003

Saarakkala S, Laasanen MS, Jurvelin JS, Törrönen K, Lammi MJ, Lappalainen R, Töyräs J. 2003. Ultrasound indentation of normal and spontaneously degenerated bovine articular cartilage. OSTEOARTHRITIS AND CARTILAGE 11: 697-705. 2003

Rieppo J, Töyräs J, Nieminen MT, Kovanen V, Hyttinen MM, Korhonen RK, Jurvelin JS, Helminen HJ. 2003. Structure-function relationships in enzymatically modified articular cartilage. CELLS TISSUES ORGANS 175: 121-132. 2003

Laasanen MS, Töyräs J, Korhonen RK, Rieppo J, Saarakkala S, Nieminen MT, Hirvonen J, Jurvelin JS. 2003. Biomechanical properties of knee articular cartilage. BIORHEOLOGY 40: 133-140. 2003

Laasanen MS, Töyräs J, Vasara AI, Hyttinen MM, Saarakkala S, Hirvonen J, Jurvelin JS, Kiviranta I. 2003. Mechano-acoustic diagnosis of cartilage degeneration and repair JOURNAL OF BONE AND JOINT SURGERY (AM) SUPPLEMENT 85-A 2: 78-84. 2003

Korhonen RK, Saarakkala S, Töyräs J, Laasanen MS, Kiviranta I, Jurvelin JS. 2003. Experimental and numerical validation for the novel configuration of an arthroscopic indentation instrument PHYSICS IN MEDICINE AND BIOLOGY 48: 1565-1576. 2003

Korhonen RK, Laasanen MS, Töyräs J, Lappalainen R, Helminen HJ, Jurvelin JS. 2003. Fibril reinforced poroelastic model predicts specifically mechanical behavior of normal, proteoglycan depleted and collagen degraded articular cartilage. JOURNAL OF BIOMECHANICS 36: 1373-1379. 2003

Hakulinen MA, Saarakkala S, Töyräs J, Kröger H, Jurvelin JS. 2003. Dual energy x-ray laser measurement of calcaneal bone mineral density PHYSICS IN MEDICINE AND BIOLOGY 48: 1741-1752. 2003

Laasanen MS, Saarakkala S, Töyräs J, Hirvonen J, Rieppo J, Korhonen RK, Jurvelin JS. 2003. Ultrasound indentation of bovine knee articular cartilage in situ. JOURNAL OF BIOMECHANICS 36: 1259-1267. 2003

Nieminen MT, Rieppo J, Silvennoinen J, Töyräs J, Hakumäki JM, Hyttinen MM, Helminen HJ, Jurvelin JS. 2002. Spatial assessment of articular cartilage proteoglycans with Gd-DTPA-enhanced T1 imaging. MAGNETIC RESONANCE IN MEDICINE 48: 640-648. 2002

Töyräs J, Nieminen HJ, Laasanen MS, Nieminen MT, Korhonen RK, Rieppo J, Hirvonen J, Helminen HJ, Jurvelin JS. 2002. Ultrasonic characterization of articular cartilage. BIORHEOLOGY 39 1,2: 161-169. 2002

Töyräs J, Nieminen MT, Kröger H, Jurvelin JS. 2002. Bone mineral density, ultrasound velocity, and broadband attenuation predict mechanical properties of trabecular bone differently. BONE 31 4: 503-507. 2002

Nieminen HJ, Töyräs J, Rieppo J, Nieminen MT, Hirvonen J, Korhonen R, Jurvelin JS. 2002. Real-time ultrasound analysis of articular cartilage degradation in vitro ULTRASOUND IN MEDICINE AND BIOLOGY 28 4: 519-525. 2002

Laasanen MS, Töyräs J, Hirvonen J, Saarakkala S, Korhonen RK, Nieminen MT, Kiviranta I, Jurvelin JS. 2002. Novel mechano-acoustic technigue and instrument for diagnosis of cartilage degeneration. PHYSIOLOGICAL MEASUREMENT 23: 491-503. 2002

Korhonen RK, Laasanen MS, Töyräs J, Rieppo J, Hirvonen J, Helminen HJ, Jurvelin JS. 2002. Comparison of the equilibrium response of articular cartilage in unconfined compression, confined compression and indentation. JOURNAL OF BIOMECHANICS 35: 903-909. 2002

Hyttinen MM, Töyräs J, Lapveteläinen T, Lindblom J, Prockop DJ, Li S-W, Arita M, Jurvelin JS, Helminen HJ. 2001. Inactivation of one allele of the type II collagen gene alters the collagen network in murine articular cartilage and makes cartilage softer. ANNALS OF THE RHEUMATIC DISEASES 60: 262-268. 2001

Lyyra-Laitinen T, Töyräs J, Kiviranta I, Jurvelin JS. 2001. Development of arthroscopic indentation technique for the diagnosis of cartilage degeneration: Kotila S, Haataja J, CSC Report on Scientific Computing 1999-2000.CSC - Scientific Computing. 181-184. 2001

Nieminen MT, Rieppo J, Töyräs J, Hakumäki JM, Silvennoinen J, Hyttinen MM, Helminen HJ, Jurvelin JS. 2001. T2 Relaxation reveals spatial collagen architecture in articular cartilage: a comparative quantitative MRI and polarized light microscopic study. MAGNETIC RESONANCE IN MEDICINE 46: 487-493. 2001

Töyräs J, Lyyra-Laitinen T, Niinimäki M, Lindgren R, Nieminen MT, Kiviranta I, Jurvelin JS. 2001. Estimation of the Young's modulus of articular cartilage using an arthroscopic indentation instrument and ultrasonic measurement of tissue thickness. JOURNAL OF BIOMECHANICS 34: 251-256. 2001

Töyräs J. 2001. Mechano-Acoustic Characterization of Articular Cartilage and Trabecular Bone. Kuopion yliopiston julkaisuja C. Luonnontieteet ja ympäristötieteet. 2001

Nieminen MT, Töyräs J, Rieppo J, Hakumäki JM, Silvennoinen J, Helminen HJ, Jurvelin JS. 2000. Quantitative MR microscopy of enzymatically degraded articular cartilage. MAGNETIC RESONANCE IN MEDICINE 43: 676-681. 2000

Lyyra-Laitinen T, Niinimäki M, Töyräs J, Lindgren R, Kiviranta I, Jurvelin JS. 1999. Optimization of the arthroscopic indentation instrument for the measurement of thin cartilage stiffness. PHYSICS IN MEDICINE AND BIOLOGY 44: 2511-2524. 1999

Töyräs J, Kröger H, Jurvelin JS. 1999. Bone properties as estimated by mineral density, ultrasound attenuation, and velocity BONE 25 6: 725-731. 1999

Töyräs J, Rieppo J, Nieminen MT, Helminen HJ, Jurvelin JS. 1999. Characterization of enzymatically induced degradation of articular cartilage using high frequency ultrasound PHYSICS IN MEDICINE AND BIOLOGY 44: 2723-2733. 1999

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