Kati Hanhineva

Babu, Ambrin Farizah; Csader, Susanne; Lok, Johnson; Gómez-Gallego, Carlos; Hanhineva, Kati; El-Nezami, Hani; Schwab, Ursula. 2021. Positive Effects of Exercise Intervention without Weight Loss and Dietary Changes in NAFLD-Related Clinical Parameters: A Systematic Review and Meta-Analysis Nutrients 13 9: 3135. 2021

Noerman, Stefania; Kokla, Marietta; Koistinen, Ville M; Lehtonen, Marko; Tuomainen, Tomi-Pekka; Brunius, Carl; Virtanen, Jyrki K; Hanhineva, Kati. 2021. Associations of the serum metabolite profile with a healthy Nordic diet and risk of coronary artery disease Clinical nutrition 40 5: 3250-3262. 2021

Herrala, Maria; Turunen, Soile; Hanhineva, Kati; Lehtonen, Marko; Mikkonen, Jopi J. W.; Seitsalo, Hubertus; Lappalainen, Reijo; Tjäderhane, Leo; Niemelä, Raija K.; Salo, Tuula; Myllymaa, Sami; Kullaa, Arja M.; Kärkkäinen, Olli. 2021. Low-Dose Doxycycline Treatment Normalizes Levels of Some Salivary Metabolites Associated with Oral Microbiota in Patients with Primary Sjögren's Syndrome Metabolites 11 9: 595. 2021

Zhang, Pei; Carlsten, Christopher; Chaleckis, Romanas; Hanhineva, Kati; Huang, Mengna; Isobe, Tomohiko; Koistinen, Ville M.; Meister, Isabel; Papazian, Stefano; Sdougkou, Kalliroi; Xie, Hongyu; Martin, Jonathan W.; Rappaport, Stephen M.; Tsugawa, Hiroshi; Walker, Douglas I.; Woodruff, Tracey J.; Wright, Robert O.; Wheelock, Craig E.. 2021. Defining the Scope of Exposome Studies and Research Needs from a Multidisciplinary Perspective Environmental science & technology letters 8 10: 839-852. 2021

Vitale, Marilena; Hanhineva, Kati; Koistinen, Ville; Auriola, Seppo; Paananen, Jussi; Costabile, Giuseppina; Della Pepa, Giuseppe; Rivellese, Angela A.; Riccardi, Gabriele; Giacco, Rosalba. 2021. Putative metabolites involved in the beneficial effects of wholegrain cereal: Nontargeted metabolite profiling approach Nutrition metabolism and cardiovascular diseases 31 4: 1156-1165. 2021

Toljamo, Anna; Koistinen, Ville; Hanhineva, Kati; Kärenlampi, Sirpa; Kokko, Harri. 2021. Terpenoid and lipid profiles vary in different Phytophthora cactorum - strawberry interactions Phytochemistry 189: 112820. 2021

Sehgal, Ratika Ilha, Mariana Vaittinen, Maija Kaminska, Dorota Männistö, Ville Kärjä, Vesa Tuomainen, Marjo Hanhineva, Kati Romeo, Stefano Pajukanta, Päivi Pihlajamäki, Jussi de Mello, Vanessa D.. 2021. Indole-3-Propionic Acid, a Gut-Derived Tryptophan Metabolite, Associates with Hepatic Fibrosis Nutrients 13 10: 3509. 2021

Poutanen, Kaisa S; Kårlund, Anna O; Gómez-Gallego, Carlos; Johansson, Daniel P; Scheers, Nathalie M; Marklinder, Ingela M; Eriksen, Anne K; Silventoinen, Pia C; Nordlund, Emilia; Sozer, Nesli; Hanhineva, Kati J; Kolehmainen, Marjukka; Landberg, Rikard. 2021. Grains - a major source of sustainable protein for health Nutrition reviews [Epub ahead of print 6 Nov 2021]: 1 - 16. 2021

Meuronen, Topi; Lankinen, Maria A.; Kärkkäinen, Olli; Laakso, Markku; Pihlajamäki, Jussi; Hanhineva, Kati; Schwab, Ursula. 2021. FADS1 rs174550 genotype and high linoleic acid diet modify plasma PUFA phospholipids in a dietary intervention study European journal of nutrition 2022; 61 2: 1109-1120. 2021

Low, Dorrain Yanwen; Micheau, Pierre; Koistinen, Ville Mikael; Hanhineva, Kati; Abrankó, László; Rodriguez-Mateos, Ana; da Silva, Andreia Bento; van Poucke, Christof; Almeida, Conceição; Andres-Lacueva, Cristina; Rai, Dilip K.; Capanoglu, Esra; Tomás Barberán, Francisco A.; Mattivi, Fulvio; Schmidt, Gesine; Gürdeniz, Gözde; Valentová, Katerina; Bresciani, Letizia; Petrásková, Lucie; Dragsted, Lars. 2021. Data sharing in PredRet for accurate prediction of retention time: Application to plant food bioactive compounds Food chemistry 357: 129757. 2021

Leyrolle, Quentin; Cserjesi, Renata; Mulders, Maria DGH; Zamariola, Giorgia; Hiel, Sophie; Gianfrancesco, Marco A; Rodriguez, Julie; Portheault, Daphnée; Amadieu, Camille; Leclercq, Sophie; Bindels, Laure B; Neyrinck, Audrey M; Cani, Patrice D; Karkkainen, Olli; Haninheva, Kati; Lanthier, Nicolas; Trefois, Pierre; Paquot, Nicolas; Cnop, Miriam; Luminet, Olivier et al.. 2021. Specific gut microbial, biological, and psychiatric profiling related to binge eating disorders: A cross-sectional study in obese patients Clinical nutrition 40 4: 2034-2044. 2021

Leyrolle, Quentin; Cserjesi, Renata; Demeure, Romane; Neyrinck, Audrey M.; Amadieu, Camille; Rodriguez, Julie; Kärkkäinen, Olli; Hanhineva, Kati; Paquot, Nicolas; Cnop, Miriam; Cani, Patrice D.; Thissen, Jean-Paul; Bindels, Laure B.; Klein, Olivier; Luminet, Olivier; Delzenne, Nathalie M.. 2021. Microbiota and Metabolite Profiling as Markers of Mood Disorders: A Cross-Sectional Study in Obese Patients Nutrients 2022; 14 1: 147. 2021

Kärkkäinen, Olli; Kokla, Marietta; Lehtonen, Marko; Auriola, Seppo; Martiskainen, Mika; Tiihonen, Jari; Karhunen, Pekka J.; Hanhineva, Kati; Kok, Eloise. 2021. Changes in the metabolic profile of human male postmortem frontal cortex and cerebrospinal fluid samples associated with heavy alcohol use Addiction biology 26 6: e13035. 2021

Jääskeläinen, Tiina; Kärkkäinen, Olli; Jokkala, Jenna; Klåvus, Anton; Heinonen, Seppo; Auriola, Seppo; Lehtonen, Marko; The FINNPEC Core Investigator Group; Hanhineva, Kati; Laivuori, Hannele. 2021. A non-targeted LC-MS metabolic profiling of pregnancy: longitudinal evidence from healthy and pre-eclamptic pregnancies Metabolomics 17 2: 20. 2021

Noerman, Stefania; Kolehmainen, Marjukka; Hanhineva, Kati. 2020. Profiling of Endogenous and Gut Microbial Metabolites to Indicate Metabotype-Specific Dietary Responses: A Systematic Review Advances in nutrition 11 5: 1237-1254. 2020

Schillemans, Tessa; Shi, Lin; Donat-Vargas, Carolina; Hanhineva, Kati; Tornevi, Andreas; Johansson, Ingegerd; Koponen, Jani; Kiviranta, Hannu; Rolandsson, Olov; Bergdahl, Ingvar A; Landberg, Rikard; Åkesson, Agneta; Brunius, Carl. 2020. Plasma metabolites associated with exposure to perfluoroalkyl substances and risk of type 2 diabetes - A nested case-control study Environment international 146: 106180. 2020

Saarinen, Markku Tapani; Kärkkäinen, Olli; Hanhineva, Kati; Tiihonen, Kirsti; Hibberd, Ashley; Mäkelä, Kari Antero; Raza, Ghulam Shere; Herzig, Karl-Heinz; Anglenius, Heli. 2020. Metabolomics analysis of plasma and adipose tissue samples from mice orally administered with polydextrose and correlations with cecal microbiota Scientific reports 10 1: 21577. 2020

Palviainen, Mari; Laukkanen, Kirsi; Tavukcuoglu, Zeynep; Velagapudi, Vidya; Kärkkäinen, Olli; Hanhineva, Kati; Auriola, Seppo; Ranki, Annamari; Siljander, Pia. 2020. Cancer Alters the Metabolic Fingerprint of Extracellular Vesicles Cancers 12 11: 3292. 2020

Turunen, Soile; Puurunen, Jenni; Auriola, Seppo; Kullaa, Arja M; Kärkkäinen, Olli; Lohi, Hannes; Hanhineva, Kati. 2020. Metabolome of canine and human saliva: a non-targeted metabolomics study Metabolomics 16 9: 90. 2020

Noerman, S; Klåvus, A; Järvelä-Reijonen, E; Karhunen, L; Auriola, S; Korpela, R; Lappalainen, R; Kujala, UM; Puttonen, S; Kolehmainen, M; Hanhineva, K. 2020. Plasma lipid profile associates with the improvement of psychological well-being in individuals with perceived stress symptoms Scientific reports 10 1: 2143. 2020

Klåvus, Anton; Kokla, Marietta; Noerman, Stefania; Koistinen, Ville M; Tuomainen, Marjo; Zarei, Iman; Meuronen, Topi; Häkkinen, Merja R; Rummukainen, Soile; Farizah Babu, Ambrin; Sallinen, Taisa; Kärkkäinen, Olli; Paananen, Jussi; Broadhurst, David; Brunius, Carl; Hanhineva, Kati. 2020. "notame": Workflow for Non-Targeted LC-MS Metabolic Profiling Metabolites 10 4: 135. 2020

González-Domínguez, Raúl; Jáuregui, Olga; Mena, Pedro; Hanhineva, Kati; Tinahones, Francisco José; Angelino, Donato; Andrés-Lacueva, Cristina. 2020. Quantifying the human diet in the crosstalk between nutrition and health by multi-targeted metabolomics of food and microbiota-derived metabolites International journal of obesity 44 12: 2372-2381. 2020

de Mello, Vanessa D; Sehgal, Ratika; Männistö, Ville; Klåvus, Anton; Nilsson, Emma; Perfilyev, Alexander; Kaminska, Dorota; Miao, Zong; Pajukanta, Päivi; Ling, Charlotte; Hanhineva, Kati; Pihlajamäki, Jussi. 2020. Serum aromatic and branched-chain amino acids associated with NASH demonstrate divergent associations with serum lipids Liver international 2021; 41 4: 754-763. 2020

Koistinen, Ville M; Tuomainen, Marjo; Lehtinen, Pekka; Peltola, Petri; Auriola, Seppo; Jonsson, Karin; Hanhineva, Kati. 2020. Side-stream products of malting: a neglected source of phytochemicals npj science of food 4 1: 21. 2020

Landberg, R; Hanhineva, K; Tuohy, K; Garcia-Aloy, M; Biskup, I; Llorach, R; Yin, X; Brennan, L; Kolehmainen, M. 2019. Biomarkers of cereal food intake Genes and nutrition 14: 28. 2019

Walle, P; Männistö, V; de Mello, VD; Vaittinen, M; Perfilyev, A; Hanhineva, K; Ling, C; Pihlajamäki, J. 2019. Liver DNA methylation of FADS2 associates with FADS2 genotypex Clinical epigenetics 11 1: 10. 2019

Tuomainen, M; Kärkkäinen, O; Leppänen, J; Auriola, S; Lehtonen, M; Savolainen, MJ; Hermansen, K; Risérus, U; Åkesson, B; Thorsdottir, I; Kolehmainen, M; Uusitupa, M; Poutanen, K; Schwab, U; Hanhineva, K. 2019. Quantitative assessment of betainized compounds and associations with dietary and metabolic biomarkers in the randomized study of the healthy Nordic diet (SYSDIET) American journal of clinical nutrition 110 5: 1108-1118. 2019

Shi, L; Brunius, C; Johansson, I; Bergdahl, IA; Rolandsson, O; van Guelpen, B; Winkvist, A; Hanhineva, K; Landberg, R. 2019. Plasma metabolite biomarkers of boiled and filtered coffee intake and their association with type 2 diabetes risk Journal of internal medicine 2020; 287 4: 405-421. 2019

Shi, L; Brunius, C; Bergdahl, IA; Johansson, I; Rolandsson, O; Donat Vargas, C; Kiviranta, H; Hanhineva, K; Åkesson, A; Landberg, R. 2019. Joint Analysis of Metabolite Markers of Fish Intake and Persistent Organic Pollutants in Relation to Type 2 Diabetes Risk in Swedish Adults Journal of nutrition 149 8: 1413-1423. 2019

Palviainen, Mari; Saari, Heikki; Kärkkäinen, Olli; Pekkinen, Jenna; Auriola, Seppo; Yliperttula, Marjo; Puhka, Maija; Hanhineva, Kati; Siljander, Pia R-M. 2019. Metabolic signature of extracellular vesicles depends on the cell culture conditions Journal of extracellular vesicles 8 1: 1596669. 2019

Männistö, V; Kaminska, D; Kärjä, V; Tiainen, M; de Mello, VD; Hanhineva, K; Soininen, P; Ala-Korpela, M; Pihlajamäki, J. 2019. Total liver phosphatidylcholine content associates with non-alcoholic steatohepatitis and glycine N-methyltransferase expression Liver international 39 10: 1895-1905. 2019

Landberg, R; Hanhineva, K. 2019. Biomarkers of a Healthy Nordic Diet-From Dietary Exposure Biomarkers to Microbiota Signatures in the Metabolome Nutrients 12 1: 27. 2019

Kokla, M; Virtanen, J; Kolehmainen, M; Paananen, J; Hanhineva, K. 2019. Random forest-based imputation outperforms other methods for imputing LC-MS metabolomics data: a comparative study Bmc bioinformatics 20 1: 492. 2019

Koistinen, VM; Kärkkäinen, O; Borewicz, K; Zarei, I; Jokkala, J; Micard, V; Rosa-Sibakov, N; Auriola, S; Aura, AM; Smidt, H; Hanhineva, K. 2019. Contribution of gut microbiota to metabolism of dietary glycine betaine in mice and in vitro colonic fermentation Microbiome 7: 103. 2019

Keski-Rahkonen, Pekka; Kolehmainen, Marjukka; Lappi, Jenni; Micard, Valerie; Jokkala, Jenna; Rosa-Sibakov, Natalia; Pihlajamäki, Jussi; Kirjavainen, Pirkka V; Mykkänen, Hannu; Poutanen, Kaisa; Gunter, Marc J; Scalbert, Augustin; Hanhineva, Kati. 2019. Decreased plasma serotonin and other metabolite changes in healthy adults after consumption of wholegrain rye: an untargeted metabolomics study American journal of clinical nutrition 109 6: 1630-1639. 2019

Hålldin, E; Eriksen, AK; Brunius, C; da Silva, AB; Bronze, M; Hanhineva, K; Aura, AM; Landberg, R. 2019. Factors Explaining Inter-Personal Variation in Plasma Enterolactone Concentrations in Humans Molecular nutrition and food research 63 16: 1801159. 2019

Cuparencu, Catalina; Praticó, Giulia; Hemeryck, Lieselot Y; Sri Harsha, Pedapati SC; Noerman, Stefania; Rombouts, Caroline; Xi, Muyao; Vanhaecke, Lynn; Hanhineva, Kati; Brennan, Lorraine; Dragsted, Lars O. 2019. Biomarkers of meat and seafood intake: an extensive literature review Genes and nutrition 14: 35. 2019

Bento-Silva, A; Koistinen, VM; Mena, P; Bronze, MR; Hanhineva, K; Sahlstrøm, S; Kitryte, V; Moco, S; Aura, AM. 2019. Factors affecting intake, metabolism and health benefits of phenolic acids: do we understand individual variability? European journal of nutrition [First Online 21 May 2019]: 1-19. 2019

Battat, Maor; Eitan, Asa; Rogachev, Ilana; Hanhineva, Kati; Fernie, Alisdair; Tohge, Takayuki; Beekwilder, Jules; Aharoni, Asaph. 2019. A MYB Triad Controls Primary and Phenylpropanoid Metabolites for Pollen Coat Patterning Plant physiology 180 1: 87-108. 2019

Ulaszewska, MM; Weinert, CH; Trimigno, A; Portmann, R; Andres Lacueva, C; Badertscher, R; Brennan, L; Brunius, C; Bub, A; Capozzi, F; Cialiè Rosso, M; Cordero, CE; Daniel, H; Durand, S; Egert, B; Ferrario, PG; Feskens, EJM; Franceschi, P; Garcia-Aloy, M; Giacomoni, F; et al [Incl Hanhineva, K]. 2018. Nutrimetabolomics: An Integrative Action for Metabolomic Analyses in Human Nutritional Studies Molecular nutrition and food research 2019; 63 1: 1800384. 2018

Tuomainen, Marjo; Lindström, Jaana; Lehtonen, Marko; Auriola, Seppo; Pihlajamäki, Jussi; Peltonen, Markku; Tuomilehto, Jaakko; Uusitupa, Matti; de Mello, Vanessa D; Hanhineva, Kati. 2018. Associations of serum indolepropionic acid, a gut microbiota metabolite, with type 2 diabetes and low-grade inflammation in high-risk individuals Nutrition and diabetes 8: 35. 2018

Shi, Lin; Brunius, Carl; Johansson, Ingegerd; Bergdahl, Ingbar A; Lindahl, Bernt; Hanhineva, Kati; Landberg, Rikard. 2018. Plasma metabolites associated with healthy Nordic dietary indexes and risk of type 2 diabetes - a nested case-control study in a Swedish population American journal of clinical nutrition 108 3: 564-575. 2018

Shi, L; Brunius, C; Lehtonen, M; Auriola, S; Bergdahl, IA; Rolandsson, O; Hanhineva, K; Landberg, R. 2018. Plasma metabolites associated with type 2 diabetes in a Swedish population: a case-control study nested in a prospective cohort. DIABETOLOGIA 61 4: 849-861. 2018

Puurunen, Jenni; Tiira, Katriina; Vapalahti, Katarooma; Lehtonen, Marko; Hanhineva, Kati; Lohi, Hannes. 2018. Fearful dogs have increased plasma glutamine and gamma-glutamyl glutamine Scientific Reports 8 1: 15976. 2018

Pentikäinen, Saara; Koistinen, Ville; Kolehmainen, Marjukka; Poutanen, Kaisa; Hanhineva, Kati; Aura, Anna-Marja. 2018. Mastication-induced release of compounds from rye and wheat breads to saliva FOOD CHEMISTRY 2019; 270: 502-508. 2018

Loppi, S; Kolosowska, N; Kärkkäinen, O; Korhonen, P; Huuskonen, M; Grubman, A; Dhungana, H; Wojciechowski, S; Pomeshchik, Y; Giordano, M; Kagechika, H; White, A; Auriola, S; Koistinaho, J; Landreth, G; Hanhineva, K; Kanninen, K; Malm, T. 2018. HX600, a synthetic agonist for RXR-Nurr1 heterodimer complex, prevents ischemia-induced neuronal damage Brain, behavior, and immunity 73: 670-681. 2018

Madawala, Samanthi R P; Brunius, Carl; Adholeya, Alok; Tripathi, Shashi Bhushan; Hanhineva, Kati; Hajazimi, Ensieh; Shi, Lin; Dimberg, Lena; Landberg, Rikard. 2018. Impact of location on composition of selected phytochemicals in wild sea buckthorn (Hippophae rhamnoides) JOURNAL OF FOOD COMPOSITION AND ANALYSIS 72: 115-121. 2018

Noerman, S; Kärkkäinen, O; Mattsson, A; Paananen, J; Lehtonen, M; Nurmi, T; Tuomainen, TP; Voutilainen, S; Hanhineva, K; Virtanen, JK. 2018. Metabolic Profiling of High Egg Consumption and the Associated Lower Risk of Type 2 Diabetes in Middle-Aged Finnish Men Molecular nutrition and food research 2019; 63 5: 1800605. 2018

Lehikoinen, Anni I; Kärkkäinen, Olli K; Lehtonen, Marko AS; Auriola, Seppo OK; Hanhineva, Kati J; Heinonen, Seppo T. 2018. Alcohol and substance use are associated with altered metabolome in the first trimester serum samples of pregnant mothers. EUROPEAN JOURNAL OF OBSTETRICS, GYNECOLOGY AND REPRODUCTIVE BIOLOGY 223: 79-84. 2018

Koistinen, VM; da Silva, AB; Abrankó, L; Low, D; Villalba, RG; Barberán, FT; Landberg, R; Savolainen, O; Alvarez-Acero, I; de Pascual-Teresa, S; Van Poucke, C; Almeida, C; Petrásková, L; Valentová, K; Durand, S; Wiczkowski, W; Szawara-Nowak, D; González-Domínguez, R; Llorach, R; Andrés-Lacueva, C; et al.. 2018. Interlaboratory Coverage Test on Plant Food Bioactive Compounds and their Metabolites by Mass Spectrometry-Based Untargeted Metabolomics Metabolites 8 3: 46. 2018

Airaksinen, Kaisa; Jokkala, Jenna; Ahonen, Ilmari; Auriola, Seppo; Kolehmainen, Marjukka; Hanhineva, Kati; Tiihonen, Kirsti. 2018. High-Fat Diet, Betaine, and Polydextrose Induce Changes in Adipose Tissue Inflammation and Metabolism in C57BL/6J Mice Molecular Nutrition & Food Research 62 23: 1800455. 2018

Jonsson, Karin; Andersson, Roger; Bach Knudsen, Knud Erik; Hallmans, Göran; Hanhineva, Kati; Katina, Kati; Kolehmainen, Marjukka; Kyrø, Cecilie; Langton, Maud; Nordlund, Emilia; Lærke, Helle Nygaard; Olsen, Anja; Poutanen, Kajsa; Tjønneland, Anne; Landberg, Rikard. 2018. Rye and health - Where do we stand and where do we go? TRENDS IN FOOD SCIENCE AND TECHNOLOGY 79: 78-87. 2018

Jääskeläinen, Tiina; Kärkkäinen, Olli; Jokkala, Jenna; Litonius, Kaisa; Heinonen, Seppo; Auriola, Seppo; Lehtonen, Marko; Hanhineva, Kati; Laivuori, Hannele; FINNPEC. 2018. A Non-Targeted LC-MS Profiling Reveals Elevated Levels of Carnitine Precursors and Trimethylated Compounds in the Cord Plasma of Pre-Eclamptic Infants Scientific reports 8: 14616. 2018

Lappalainen, Marika; Jokkala, Jenna; Juutilainen, Auni; Hämäläinen, Sari; Koivula, Irma; Jantunen, Esa; Hanhineva, Kati; Pulkki, Kari. 2018. Novel Biomarker Candidates for Febrile Neutropenia in Hematological Patients Using Nontargeted Metabolomics Disease markers 2018: 6964529. 2018

Koistinen, VM; Mattila, O; Katina, K; Poutanen, K; Aura, AM; Hanhineva, K. 2018. Metabolic profiling of sourdough fermented wheat and rye bread. Scientific Reports 8: 5684. 2018

Kärkkäinen, Olli; Tuomainen, Tomi; Koistinen, Ville; Tuomainen, Marjo; Leppänen, Jukka; Laitinen, Tuomo; Lehtonen, Marko; Rysä, Jaana; Auriola, Seppo; Poso, Antti; Tavi, Pasi; Hanhineva, Kati. 2018. Whole grain intake associated molecule 5-aminovaleric acid betaine decreases ß-oxidation of fatty acids in mouse cardiomyocytes Scientific reports 8: 13036. 2018

Kärkkäinen, Olli; Tuomainen, Tomi; Mutikainen, Maija; Lehtonen, Marko; Ruas, Jorge L; Hanhineva, Kati; Tavi, Pasi. 2018. Heart specific PGC-1[alfa] deletion identifies metabolome of cardiac restricted metabolic heart failure CARDIOVASCULAR RESEARCH 2019; 115 1: 107-118. 2018

Kärkkäinen, O; Lankinen, MA; Vitale, M; Jokkala, J; Leppänen, J; Koistinen, V; Lehtonen, M; Giacco, R; Rosa-Sibakov, N; Micard, V; Rivellese, AAA; Schwab, U; Mykkänen, H; Uusitupa, M; Kolehmainen, M; Riccardi, G; Poutanen, K; Auriola, S; Hanhineva, K. 2018. Diets rich in whole grains increase betainized compounds associated with glucose metabolism American journal of clinical nutrition 108 5: 971-979. 2018

Koistinen Ville M, Hanhineva Kati. 2017. Microbial and endogenous metabolic conversions of rye phytochemicals. Molecular Nutrition & Food Research 61 7: 1600627. 2017

Koistinen Ville Mikael, Hanhineva Kati. 2017. Mass spectrometry-based analysis of whole-grain phytochemicals. Critical reviews in food science and nutrition 57 8: 1688-1709. 2017

Koistinen VM, Nordlund E, Katina K, Mattila I, Poutanen K, Hanhineva K, Aura A-M. 2017. Effect of Bioprocessing on the In Vitro Colonic Microbial Metabolism of Phenolic Acids from Rye Bran Fortified Breads. Journal of agricultural and food chemistry 65 9: 1854-1864. 2017

de Mello VD, Paananen J, Lindstrom J, Lankinen MA, Shi L, Kuusisto J, Pihlajamaki J, Auriola S, Lehtonen M, Rolandsson O, Bergdahl IA, Nordin E, Ilanne-Parikka P, Keinänen-Kiukaanniemi S, Landberg R, Eriksson JG, Tuomilehto J, Hanhineva K, Uusitupa M. 2017. Indolepropionic acid and novel lipid metabolites are associated with a lower risk of type 2 diabetes in the Finnish Diabetes Prevention Study. Scientific Reports 7: 46337. 2017

de Mello VD, Lankinen MA, Lindström J, Puupponen-Pimiä R, Laaksonen DE, Pihlajamäki J, Lehtonen M, Uusitupa M, Tuomilehto J, Kolehmainen M, Törrönen R, Hanhineva K. 2017. Fasting serum hippuric acid is elevated after bilberry (Vaccinium myrtillus) consumption and associates with improvement of fasting glucose levels and insulin secretion in persons at high risk of developing type 2 diabetes. Molecular Nutrition & Food Research 61 9: 1700019. 2017

Hanhineva Kati, Pasanen Markku. 2017. Metabolomics Applications in Herbal Medicine. Teoksessa: Pelkonen O, Duez P, Vuorela P, Vuorela H (toim.) Toxicology of Herbal Products. Springer. s. 165-178. 2017

Koistinen Ville Mikael, Katina Kati, Nordlund Emilia, Poutanen Kaisa, Hanhineva Kati. 2016. Changes in the phytochemical profile of rye bran induced by enzymatic bioprocessing and sourdough fermentation. FOOD RESEARCH INTERNATIONAL 89 Part 3: 1106-1115. 2016

Kårlund Anna, Hanhineva Kati, Lehtonen Marko, McDougall Gordon J, Stewart Derek, Karjalainen Reijo O. 2016. Non-targeted metabolite profiling highlights the potential of strawberry leaves as a resource for specific bioactive compounds. JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE 2017; 97 7: 2182-2190. 2016

Kårlund Anna, Moor Ulvi, McDougall Gordon, Lehtonen Marko, Karjalainen Reijo O, Hanhineva Kati. 2016. Metabolic profiling discriminates between strawberry (Fragaria×ananassa Duch.) cultivars grown in Finland or Estonia. FOOD RESEARCH INTERNATIONAL 89 Part 1: 647-653. 2016

Puurunen Jenni, Sulkama Sini, Tiira Katriina, Araujo Cesar, Lehtonen Marko, Hanhineva Kati, Lohi Hannes. 2016. A non-targeted metabolite profiling pilot study suggests that tryptophan and lipid metabolisms are linked with ADHD-like behaviours in dogs. BEHAVIORAL AND BRAIN FUNCTIONS 12: 27. 2016

Puurunen Jenni, Tiira Katriina, Lehtonen Marko, Hanhineva Kati, Lohi Hannes. 2016. Non-targeted metabolite profiling reveals changes in oxidative stress, tryptophan and lipid metabolisms in fearful dogs. BEHAVIORAL AND BRAIN FUNCTIONS 12 1: 7. 2016

Tovar Juscelino, de Mello Vanessa D, Nilsson Anne, Johansson Maria, Paananen Jussi, Lehtonen Marko, Hanhineva Kati, Björck Inger. 2016. Reduction in cardiometabolic risk factors by a multifunctional diet is mediated via several branches of metabolism as evidenced by non-targeted metabolite profiling approach. Molecular Nutrition & Food Research [Epub ahead of print 8 Nov 2016]: 1-12. 2016

Lankinen Maria A., Hanhineva Kati, Kolehmainen Marjukka, Lehtonen Marko, Auriola Seppo, Mykkänen Hannu, Poutanen Kaisa, Schwab Ursula, Uusitupa Matti. 2015. CMPF Does Not Associate with Impaired Glucose Metabolism in Individuals with Features of Metabolic Syndrome. PLOS ONE [ONLINE] 10 4: e0124379. 2015

Savolainen Otto, Pekkinen Jenna, Katina Kati, Poutanen Kaisa, Hanhineva Kati. 2015. Glycosylated Benzoxazinoids Are Degraded during Fermentation of Wheat Bran. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 63 25: 5943-5949. 2015

Pekkinen Jenna, Rosa-Sibakov Natalia, Micard Valerie, Keski-Rahkonen Pekka, Lehtonen Marko, Poutanen Kaisa, Mykkänen Hannu, Hanhineva Kati. 2015. Amino acid-derived betaines dominate as urinary markers for rye bran intake in mice fed high-fat diet - a non-targeted metabolomics study. Molecular Nutrition & Food Research 59: 1550-1562. 2015

Kårlund Anna, Hanhineva Kati, Lehtonen Marko, Karjalainen Reijo O, Sandell Mari. 2015. Nontargeted Metabolite Profiles and Sensory Properties of Strawberry Cultivars Grown both Organically and Conventionally. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 63 3: 1010-1019. 2015

Hanhineva Kati. 2015. Application of Metabolomics to Assess Effects of Controlled Dietary Interventions. Current Nutrition Reports 4 4: 365-376. 2015

Hanhineva Kati, Brunius Carl, Andersson Agneta, Marklund Matti, Juvonen Risto, Keski-Rahkonen Pekka, Auriola Seppo, Landberg Rikard. 2015. Discovery of urinary biomarkers of whole grain rye intake in free-living subjects using non-targeted LC-MS metabolite profiling. Molecular Nutrition & Food Research [epub ahead of print 10 SEP 2015]: -. 2015

Bondia-Pons Isabel, Alfredo Martinez Jose, de la Iglesia Rocio, Lopez-Legarrea Patricia, Poutanen Kaisa, Hanhineva Kati, de los Angeles Zulet Maria. 2015. Effects of short- and long-term Mediterranean-based dietary treatment on plasma LC-QTOF/MS metabolic profiling of subjects with metabolic syndrome features: The Metabolic Syndrome Reduction in Navarra (RESMENA) randomized controlled trial. Molecular Nutrition & Food Research 59 4: 711-728. 2015

Bondia-Pons Isabel, Savolainen Otto, Törrönen Riitta, Martinez J Alfredo, Poutanen Kaisa, Hanhineva Kati. 2014. Metabolic profiling of Goji berry extracts for discrimination of geographical origin by non-targeted liquid chromatography coupled to quadrupole time-of-flight mass spectrometry. FOOD RESEARCH INTERNATIONAL 63: 132-138. 2014

Hanhineva K, Pihlava J, Mykkänen H, Poutanen K. 2014. Benzoxazinoids in rye and rye-derived products: Poutanen Kaisa, Åman Per, Rye and health. 121-129. 2014

Hanhineva Kati, Keski-Rahkonen Pekka, Lappi Jenni, Katina Kati, Pekkinen Jenna, Savolainen Otto, Timonen Oskari, Paananen Jussi, Mykkänen Hannu, Poutanen Kaisa. 2014. The postprandial plasma rye fingerprint includes benzoxazinoid-derived phenylacetamide sulfates. JOURNAL OF NUTRITION 144 7: 1016-22. 2014

Hanhineva Kati, Lankinen Maria A, Pedret Anna, Schwab Ursula, Kolehmainen Marjukka, Paananen Jussi, de Mello Vanessa, Sola Rosa, Lehtonen Marko, Poutanen Kaisa, Uusitupa Matti, Mykkänen Hannu. 2014. Nontargeted metabolite profiling discriminates diet-specific biomarkers for consumption of whole grains, fatty fish, and bilberries in a randomized controlled trial. JOURNAL OF NUTRITION 2015; 145: 7-17. 2014

Pekkinen Jenna, Rosa Natalia N, Savolainen Otto-Ilari, Keski-Rahkonen Pekka, Mykkänen Hannu, Poutanen Kaisa, Micard Valérie, Hanhineva Kati. 2014. Disintegration of wheat aleurone structure has an impact on the bioavailability of phenolic compounds and other phytochemicals as evidenced by altered urinary metabolite profile of diet-induced obese mice. NUTRITION AND METABOLISM 11 1: 1-15. 2014

Penalvo José L, Hanhineva Kati, Adlercreutz Herman. 2014. Bioavailability of rye lignans and their relevance for human health: Poutanen Kaisa, Åman Per, Rye and health. 71-84. 2014

Rosa Natalia Nicole, Pekkinen Jenna, Zavala Karla, Fouret Gilles, Korkmaz Ayhan, Feillet-Coudray Christine, Atalay Mustafa, Hanhineva Kati, Mykkänen Hannu, Poutanen Kaisa, Micard Valérie. 2014. Impact of Wheat Aleurone Structure on Metabolic Disorders Caused by a High-Fat Diet in Mice. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 62 41: 10101-9. 2014

Savolainen Otto I, Coda Rossana, Suomi Katja, Katina Kati, Juvonen Riikka, Hanhineva Kati, Poutanen Kaisa. 2014. The role of oxygen in the liquid fermentation of wheat bran. FOOD CHEMISTRY 153: 424-431. 2014

Pekkinen Jenna, Olli Kaisa, Huotari Anne, Tiihonen Kirsti, Keski-Rahkonen Pekka, Lehtonen Marko, Auriola Seppo, Kolehmainen Marjukka, Mykkänen Hannu, Poutanen Kaisa, Hanhineva Kati. 2013. Betaine supplementation causes increase in carnitine metabolites in the muscle and liver of mice fed a high-fat diet as studied by nontargeted LC-MS metabolomics approach. Molecular Nutrition & Food Research 57: 1959-1968. 2013

Hanhineva K, Barri T, Kolehmainen M, Pekkinen J, Pihlajamäki J, Vesterbacka A, Solano-Aguilar G, Mykkänen H, Dragsted LO, Urban JF, Poutanen K. 2013. Comparative nontargeted profiling of metabolic changes in tissues and biofluids in high-fat diet-fed Ossabaw pig. JOURNAL OF PROTEOME RESEARCH 12: 3980-3992. 2013

Bondia-Pons I, Barri T, Hanhineva K, Juntunen K, Dragstedt LO, Mykkänen H, Poutanen K. 2013. UPLC-QTOF/MS metabolic profiling unveils urinary changes in humans after a whole grain rye versus refined wheat bread intervention. Molecular Nutrition & Food Research 57 3: 412-422. 2013

Hanhineva K, Aura A-M, Rogachev I, Matero S, Skov T, Aharoni A, Poutanen K, Mykkänen H. 2012. In Vitro Microbiotic Fermentation Causes an Extensive Metabolite Turnover of Rye Bran Phytochemicals. PLOS ONE [ONLINE] 7 6: e39322. 2012

Moazzami AA, Bondia-Pons I, Hanhineva K, Juntunen K, Antl N, Poutanen K, Mykkänen H. 2012. Metabolomics reveals the metabolic shifts following an intervention with rye bread in postmenopausal women - a randomized control trial. NUTRITION JOURNAL 11: 88-. 2012

Hanhineva K, Rogachev I, Aura AM, Aharoni A, Poutanen K, Mykkänen H. 2011. Qualitative characterization of benzoxazinoid derivatives in whole grain rye and wheat by LC-MS metabolite profiling. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 59: 921-927. 2011

Hanhineva Kati, Kärenlampi Sirpa O., Aharoni Asaph. 2011. Recent advances in strawberry metabolomics: Husaini Amhad M., Genomics, Transgenics, Molecular Breeding and Biotechnology of Strawberry. Genes, Genomes and Genomics 5. 65-75. 2011

Hanhiveva Kati, Rogachev Ilana, Aura Anna-Marja, Aharoni Asaph, Poutanen Kaisa, Mykkänen Hannu. 2011. Identification of novel lignans in the whole grain rye bran by non-targeted LC-MS metabolic profiling METABOLOMICS 2011: Online, 1-11. 2011

Hanhineva K, Törrönen R, Bondia-Pons I, Pekkinen J, Kolehmainen M, Mykkänen H, Poutanen K.. 2010. Impact of dietary polyphenols on carbohydrate metabolism. INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE 11: 1365-1402. 2010

Hanhineva K, Anttonen MJ, Kokko H, Soininen P, Laatikainen R, Kärenlampi S, Rogachev I, Aharoni A. 2009. Stilbene synthase gene transfer resulted in down regulation of endogenous chalcone synthase in strawberry (Fragaria x ananassa) and led to the identification of novel phenylpropanoid glucosides: Hanke M-V, Dunemann F, Flachowsky H, Proceedings of the First International Symposium on Biotechnology of Fruit Species Bioftechfruit 2008.International Society for Horticultural Science . Acta Horticulturae. 673-679. 2009

Hanhineva K, Kokko H, Siljanen H, Rogachev I, Aharoni A & Kärenlampi SO. 2009. Stilbene synthase gene transfer caused alterations in the phenylpropanoid metabolism of transgenic strawberry (Fragaria x ananassa). JOURNAL OF EXPERIMENTAL BOTANY 60 7: 2093-2106. 2009

Hanhineva K, Soininen P, Anttonen MJ, Kokko H, Rogachev I, Aharoni A, Laatikainen R & Kärenlampi S. 2009. NMR and UPLC-qTOF-MS/MS characterisation of novel phenylethanol derivatives of phenylpropanoid glucosides from the leaves of strawberry (Fragaria x ananassa cv. Jonsok). PHYTOCHEMICAL ANALYSIS 20: 353-364. 2009

Hanhineva K, Soininen P, Anttonen MJ, Kokko H, Rogachev I, Aharoni A, Laatikainen R, Kärenlampi S. 2009. NMR and UPLC-qTOF-MS/MS characterisation of novel phenylethanol derivates of phenylpropanoid glucosides from the leaves of strawberry (Fragaria x ananassa cv. Jonsok). PHYTOCHEMICAL ANALYSIS 20: 353-364. 2009

Hanhineva K. 2008. Metabolic Engineering of Phenolic Biosynthesis Pathway and Metabolite Profiling of Strawberry (Fragaria x ananassa). Kuopion yliopisto. Kuopion yliopiston julkaisuja C. Luonnontieteet ja ympäristötieteet. 2008

Hanhineva K, Kokko H, Kärenlampi S. 2007. Generation of genetically modified strawberries in temporary immersion bioreactor system: Xu Z, Li J, Xue Y, Yang W, Biotechnology and Sustainable Agriculture 2006 and Beyond. Proceedings of the 11th IAPTC&B Congress.Springer. 115-118. 2007

Hanhineva KJ, Kärenlampi SO. 2007. Production of transgenic strawberries by temporary immersion bioreactor system and verification by TAIL-PCR. BMC BIOTECHNOLOGY 7 11. 2007

Hanhineva K, Kokko H, Kärenlampi S. 2005. Shoot regeneration from leaf explants of five strawberry (Fragaria x ananassa) cultivars in temporary immersion bioreactor system. IN VITRO CELLULAR AND DEVELOPMENT BIOLOGY - PLANT 41 6: 826-831. 2005

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