Matti Uusitupa
Professori, Emeritus
Lääketieteen laitos, Kansanterveystieteen ja kliinisen ravitsemustieteen yksikkö
matti.uusitupa@uef.fi
Julkaisut
659 kappaletta-
Association of omega 3 polyunsaturated fatty acids with incident chronic kidney disease: pooled analysis of 19 cohorts
Ong, Kwok Leung; Marklund, Matti; Huang, Liping; Rye, Kerry-Anne; Hui, Nicholas; Pan, Xiong-Fei; Rebholz, Casey M; Kim, Hyunju; Steffen, Lyn M; van Westing, Anniek C; Geleijnse, Johanna M; Hoogeveen, Ellen K; Chen, Yun-Yu; Chien, Kuo-Liong; Fretts, Amanda M; Lemaitre, Rozenn N; Imamura, Fumiaki; Forouhi, Nita G; Wareham, Nicholas J; Birukov, Anna; Jäger, Susanne; Kuxhaus, Olga; Schulze, Matthias B; de Mello, Vanessa Derenji; Tuomilehto, Jaakko; Uusitupa, Matti; Lindström, Jaana; Tintle, Nathan; . 2023. BMJ. 380: -
Combination of Multiple Low-Risk Lifestyle Behaviors and Incident Type 2 Diabetes: A Systematic Review and Dose-Response Meta-analysis of Prospective Cohort Studies
Khan, Tauseef A.; Field, David; Chen, Victoria; Ahmad, Suleman; Mejia, Sonia Blanco; Kahleová, Hana; Rahelić, Dario; Salas-Salvadó, Jordi; Leiter, Lawrence A.; Uusitupa, Matti; Kendall, Cyril W.C.; Sievenpiper, John L.. 2023. Diabetes care. 46: 643-656 -
Diabeteksen kansallisen ehkäisyhankkeen pitkäaikaiset vaikutukset ja merkitys
Uusitupa, Matti; Saaristo, Timo; Rintamäki, Reeta; Pölönen, Auli; Valtanen, Mikko; Rautio, Nina; Risku, Sari; Länsipuro, Liisa; Hirsso, Päivi; Ahtiainen, Petteri; Saltevo, Juha; Keinänen-Kiukaanniemi, Sirkka; Moilanen, Leena; Lindström, Jaana; Peltonen, Markku; Oksa, Heikki; Tuomilehto, Jaakko . 2023. DIABETES JA LÄÄKÄRI. 52: 9-16 -
Eating behavior dimensions and 9-year weight loss maintenance: a sub-study of the Finnish Diabetes prevention study
Salmela, Jutta; Konttinen, Hanna; Lappalainen, Raimo; Muotka, Joona; Antikainen, Anne; Lindström, Jaana; Tuomilehto, Jaakko; Uusitupa, Matti; Karhunen, Leila. 2023. International journal of obesity. 47: 564-573 -
Evidence-based European recommendations for the dietary management of diabetes
The Diabetes and Nutrition Study Group (DNSG) of the European Association for the Study of Diabetes (EASD). 2023. Diabetologia. 66: 965-985 -
Genome-wide association study and functional characterization identifies candidate genes for insulin-stimulated glucose uptake
Williamson, Alice; Norris, Dougall M.; Yin, Xianyong; Broadaway, K. Alaine; Moxley, Anne H.; Vadlamudi, Swarooparani; Wilson, Emma P.; Jackson, Anne U.; Ahuja, Vasudha; Andersen, Mette K.; Arzumanyan, Zorayr; Bonnycastle, Lori L.; Bornstein, Stefan R.; Bretschneider, Maxi P.; Buchanan, Thomas A.; Chang, Yi-Cheng; Chuang, Lee-Ming; Chung, Ren-Hua; Clausen, Tine D.; Damm, Peter; Delgado, Graciela E.; de Mello, Vanessa D.; Dupuis, Josée; Dwivedi, Om P.; Erdos, Michael R.; Silva, Lilian Fernandes; F. 2023. Nature genetics. 55: 973-983 -
Lifestyle Intervention Guided by Group and Internet-Based Counseling in the T2D-GENE Trial Supports Its Applicability and Feasibility
Schwab, Ursula; Lankinen, Maria; Uusitupa, Matti; Laakso, Markku. 2023. Nutrients. 15: -
Not all very-low-carbohydrate diets are created equal. Reply to Conte C, Camajani E, Lai A, Caprio M [letter]
Reynolds, Andrew N; Kahleova, Hana; Uusitupa, Matti; Hermansen, Kjeld; Aas, Anne Marie; Schwab, Ursula; Lean, Michael EJ; Pfeiffer, Andreas; Salas-Salvadó, Jordi; Mann, Jim I. 2023. Diabetologia. 66: 1754-1755 -
The effect of vitamin D3 supplementation on atrial fibrillation in generally healthy men and women: the Finnish Vitamin D Trial
Virtanen, Jyrki K; Hantunen, Sari; Lamberg-Allardt, Christel; Manson, JoAnn E; Nurmi, Tarja; Uusitupa, Matti; Voutilainen, Ari; Tuomainen, Tomi-Pekka. 2023. American heart journal. 264: 177-182 -
Towards Individually Tailored Diets in Prevention and Treatment of Diabetes?
Uusitupa, Matti; Schwab, Ursula. 2023. Nutrients. 15: -
Type 2 Diabetes Prevention Programs — From Proof-of-Concept Trials to National Intervention and Beyond
Tuomilehto, Jaakko; Uusitupa, Matti; Gregg, Edward W.; Lindström, Jaana. 2023. Journal of clinical medicine. 12: -
Analysis of the SYSDIET Healthy Nordic Diet randomized trial based on metabolic profiling reveal beneficial effects on glucose metabolism and blood lipids
Gürdeniz, Gözde; Uusitupa, Matti; Hermansen, Kjeld; Savolainen, Markku J.; Schwab, Ursula; Kolehmainen, Marjukka; Brader, Lea; Cloetens, Lieselotte; Herzig, Karl-Heinz; Hukkanen, Janne; Rosqvist, Fredrik; Ulven, Stine Marie; Gunnarsdóttir, Ingibjörg; Thorsdottir, Inga; Oresic, Matej; Poutanen, Kaisa S.; Risérus, Ulf; Åkesson, Björn; Dragsted, Lars Ove. 2022. Clinical nutrition. 41: 441-451 -
Genetic Predictors of Change in Waist Circumference and Waist-to-Hip Ratio With Lifestyle Intervention: The Trans-NIH Consortium for Genetics of Weight Loss Response to Lifestyle Intervention
McCaffery, Jeanne M.; Jablonski, Kathleen A.; Pan, Qing; Astrup, Arne; Revsbech Christiansen, Malene; Corella, Dolores; Corso, Lauren M.L.; Florez, Jose C.; Franks, Paul W.; Gardner, Christopher; Hansen, Torben; Kilpeläinen, Tuomas O.; Knowler, William C.; Lindström, Jaana; Saris, Wim H.M.; Sørensen, Thorkild I.A.; Tuomilehto, Jaakko; Uusitupa, Matti; Wing, Rena R.; Agurs-Collins, Tanya. 2022. Diabetes. 71: 669-676 -
Indolepropionic Acid, a Gut Bacteria-Produced Tryptophan Metabolite and the Risk of Type 2 Diabetes and Non-Alcoholic Fatty Liver Disease
Sehgal, Ratika; de Mello, Vanessa D.; Männistö, Ville; Lindström, Jaana; Tuomilehto, Jaakko; Pihlajamäki, Jussi; Uusitupa, Matti. 2022. Nutrients. 14: -
Longitudinal Branched-Chain Amino Acids, Lifestyle Intervention, and Type 2 Diabetes in the Finnish Diabetes Prevention Study
Kivelä, Jemina; Meinilä, Jelena; Uusitupa, Matti; Tuomilehto, Jaakko; Lindström, Jaana. 2022. Journal of clinical endocrinology and metabolism. 107: 2844-2853 -
Nordic dietary patterns and cardiometabolic outcomes: a systematic review and meta-analysis of prospective cohort studies and randomised controlled trials
Massara, Paraskevi; Zurbau, Andreea; Glenn, Andrea J; Chiavaroli, Laura; Khan, Tauseef A; Viguiliouk, Effie; Mejia, Sonia Blanco; Comelli, Elena M; Chen, Victoria; Schwab, Ursula; Risérus, Ulf; Uusitupa, Matti; Aas, Anne-Marie; Hermansen, Kjeld; Thorsdottir, Inga; Rahelić, Dario; Kahleová, Hana; Salas-Salvadó, Jordi; Kendall, Cyril WC; Sievenpiper, John L. 2022. Diabetologia. 65: 2011-2031 -
PUFA ω-3 and ω-6 biomarkers and sleep: a pooled analysis of cohort studies on behalf of the Fatty Acids and Outcomes Research Consortium (FORCE)
Murphy, Rachel A; Tintle, Nathan; Harris, William S; Darvishian, Maryam; Marklund, Matti; Virtanen, Jyrki K; Hantunen, Sari; de Mello, Vanessa D; Tuomilehto, Jaakko; Lindström, Jaana; Bolt, Matthew A; Brouwer, Ingeborg A; Wood, Alexis C; Senn, Mackenzie; Redline, Susan; Tsai, Michael Y; Gudnason, Vilmundur; Eiriksdottir, Gudny; Lindberg, Eva; Shadyab, Aladdin H; Liu, Buyun; Carnethon, Mercedes; Uusitupa, Matti; Djousse, Luc; Risérus, Ulf; Lind, Lars; van Dam, Rob M; Koh, Woon-Puay; Shi, Peilin; . 2022. American journal of clinical nutrition. 115: 864-876 -
Sources of animal proteins and type 2 diabetes risk – decreasing the consumption of red meat is well grounded
Uusitupa, Matti. 2022. Diabetes research and clinical practice. 191: -
Vitamin D supplementation and prevention of cardiovascular disease and cancer in the Finnish Vitamin D Trial: a randomized controlled trial
Virtanen, Jyrki K; Nurmi, Tarja; Aro, Antti; Bertone-Johnson, Elizabeth R; Hyppönen, Elina; Kröger, Heikki; Lamberg-Allardt, Christel; Manson, JoAnn E; Mursu, Jaakko; Mäntyselkä, Pekka; Suominen, Sakari; Uusitupa, Matti; Voutilainen, Ari; Tuomainen, Tomi-Pekka; Hantunen, Sari. 2022. American journal of clinical nutrition. 115: 1300-1310 -
Diabetes sairautena ja sen ravitsemus- ja muu hoito
Uusitupa, Matti. Teoksessa: Mutanen, Marja; Niinikoski, Harri; Schwab, Ursula; Uusitupa, Matti(toim.) , 2021. Ravitsemustiede (8. uud. painos). s. 426-456. Duodecim -
Fruit and Vegetables consumption and Type 2 diabetes prevention
Uusitupa, Matti. 2021. The Global Fruit & Veg Newsletter. : - -
Heikentynyt glukoosinsieto, insuliiniresistenssi ja metabolinen oireyhtymä ja niiden ehkäisy
Uusitupa, Matti. Teoksessa: Mutanen, Marja; Niinikoski, Harri; Schwab, Ursula; Uusitupa, Matti(toim.) , 2021. Ravitsemustiede (8. uud. painos). s. 402-403. Duodecim -
Kehon koostumuksen mittaaminen
Fogelholm, Mikael; Uusitupa, Matti. Teoksessa: Mutanen, Marja; Niinikoski, Harri; Schwab, Ursula; Uusitupa, Matti(toim.) , 2021. Ravitsemustiede (8. uud. painos). s. 279-286. Duodecim -
Kihti ja nivelreuma
Uusitupa, Matti. Teoksessa: Mutanen, Marja; Niinikoski, Harri; Schwab, Ursula; Uusitupa, Matti(toim.) , 2021. Ravitsemustiede (8. uud. painos). s. 541-545. Duodecim -
Lihavuuden ehkäisy
Uusitupa, Matti. Teoksessa: Mutanen, Marja; Niinikoski, Harri; Schwab, Ursula; Uusitupa, Matti(toim.) , 2021. Ravitsemustiede (8. uud. painos). s. 398-400. Duodecim -
Lihavuuden hoito
Uusitupa, Matti. Teoksessa: Mutanen, Marja; Niinikoski, Harri; Schwab, Ursula; Uusitupa, Matti(toim.) , 2021. Ravitsemustiede (8. uud. painos). s. 416-424. Duodecim -
Lihavuuden syyt
Uusitupa, Matti. Teoksessa: Mutanen, Marja; Niinikoski, Harri; Schwab, Ursula; Uusitupa, Matti(toim.) , 2021. Ravitsemustiede (8. uud. painos). s. 409-414. Duodecim -
Lihavuus sairautena
Uusitupa, Matti. Teoksessa: Mutanen, Marja; Niinikoski, Harri; Schwab, Ursula; Uusitupa, Matti(toim.) , 2021. Ravitsemustiede (8. uud. painos). s. 405-408. Duodecim -
Long-term outcomes of lifestyle intervention to prevent type 2 diabetes in people at high risk in primary health care
Rintamäki, Reeta; Rautio, Nina; Peltonen, Markku; Jokelainen, Jari; Keinänen-Kiukaanniemi, Sirkka; Oksa, Heikki; Saaristo, Timo; Puolijoki, Hannu; Saltevo, Juha; Tuomilehto, Jaakko; Uusitupa, Matti; Moilanen, Leena. 2021. Primary care diabetes. 15: 444-450 -
Mitä suomalainen tyypin 2 diabeteksen ehkäisytutkimus DPS on opettanut?
Lindström, Jaana; Uusitupa, Matti; Eriksson, Johan; Ilanne-Parikka, Pirjo; Keinänen-Kiukaanniemi, Sirkka; Tuomilehto, Jaakko. 2021. Duodecim. 137: 2399-2406 -
Ravitsemustiede
Mutanen, Marja; Niinikoski, Harri; Schwab, Ursula; Uusitupa, Matti. 2021. . 8. uud. painos. Duodecim -
Ravitsemustilan arviointi ja ravinnonsaannin tehostaminen
Uusitupa, Matti; Fogelholm; Schwab, Ursula. Teoksessa: Mutanen, Marja; Niinikoski, Harri; Schwab, Ursula; Uusitupa, Matti(toim.) , 2021. Ravitsemustiede (8. uud. painos). s. 293-303. Duodecim -
Serum Levels of Plasmalogens and Fatty Acid Metabolites Associate with Retinal Microangiopathy in Participants from the Finnish Diabetes Prevention Study
de Mello, Vanessa Derenji; Selander, Tuomas; Lindström, Jaana; Tuomilehto, Jaakko; Uusitupa, Matti; Kaarniranta, Kai. 2021. Nutrients. 13: 4452 -
Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability
Mägi, Reedik; Hottenga, Jouke- Jan; Grallert, Harald; Perry, John R. B.; Bouatia-Naji, Nabila; Marullo, Letizia; Rybin, Denis; Jansen, Rick; Min, Josine L.; Dimas, Antigone S.; Ulrich, Anna; Zudina, Liudmila; Gådin, Jesper R.; Jiang, Longda; Faggian, Alessia; Bonnefond, Amélie; Fadista, Joao; Stathopoulou, Maria G.; Isaacs, Aaron; Willems, Sara M et al. [incl. Kuusisto, Johanna; Laakso, Markku; Lakka, Timo, Uusitupa, Matti]. 2021. Nature communications. 12: 24 -
Sydämen vajaatoiminta
Uusitupa, Matti. Teoksessa: Mutanen, Marja; Niinikoski, Harri; Schwab, Ursula; Uusitupa, Matti(toim.) , 2021. Ravitsemustiede (8. uud. painos). s. 533-535. Duodecim -
Sydän- ja verisuonitautien ehkäisy ja riskitekijöiden lääkkeetön hoito
Schwab, Ursula; Uusitupa, Matti; Niinikoski, Harri. Teoksessa: Mutanen, Marja; Niinikoski, Harri; Schwab, Ursula; Uusitupa, Matti(toim.) , 2021. Ravitsemustiede (8. uud. painos). s. 373-397. Duodecim -
Syömisen säätely
Uusitupa, Matti; Karhunen, Leila. Teoksessa: Mutanen, Marja; Niinikoski, Harri; Schwab, Ursula; Uusitupa, Matti(toim.) , 2021. Ravitsemustiede (8. uud. painos). s. 404-405. Duodecim -
Tehohoitopotilaan ravitsemushoito
Ala-Kokko, Tero; Bäcklund, Minna; Schwab, Ursula; Niinikoski, Harri; Uusitupa, Matti. Teoksessa: Mutanen, Marja; Niinikoski, Harri; Schwab, Ursula; Uusitupa, Matti(toim.) , 2021. Ravitsemustiede (8. uud. painos). s. 606-620. Duodecim -
The trans-ancestral genomic architecture of glycemic traits
Chen, J; Spracklen, CN; Marenne, G; Varshney, A; Corbin, LJ; Luan, J; Willems, SM; Wu, Y; Zhang, X; Horikoshi, M; Boutin, TS; Mägi, R; Waage, J; Li-Gao, R; Chan, KHK; Yao, J; Anasanti, MD; Chu, AY; Claringbould, A; Heikkinen, J; et al. [incl. Kuulasmaa, T; Kuusisto, J; Laakso, M; Lakka, T; Uusitupa, M; Vangipurapu, J]. 2021. Nature genetics. 53: 840-860 -
Tyypin 2 diabeteksen Käypä hoito -suosituksessa laihduttaminen jää sivuosaan
Mustajoki, Pertti; Uusitupa, Matti. 2021. Duodecim. 137: 654 - 655 -
Tyypin 2 diabeteksen ehkäisy
Uusitupa, Matti. Teoksessa: Mutanen, Marja; Niinikoski, Harri; Schwab, Ursula; Uusitupa, Matti(toim.) , 2021. Ravitsemustiede (8. uud. painos). s. 400-402. Duodecim -
Uudet tutkimusmenetelmät ja yksilöity ravitsemushoito
Uusitupa, Matti. Teoksessa: Mutanen, Marja; Niinikoski, Harri; Schwab, Ursula; Uusitupa, Matti(toim.) , 2021. Ravitsemustiede (8. uud. painos). s. 312-323. Duodecim -
Covid-19-tauti muistuttaa lihavuuden hoidon merkityksestä
Uusitupa, Matti; Mustajoki, Pertti; Pietiläinen, Kirsi. 2020. Lääkärilehti. 75: 1736 -
Divergent pathologies and treatment options for diabetic neuropathies
Uusitupa, Matti; Niskanen, Leo; Laitinen, Tomi. 2020. Diabetologia. 63: 1947-1948 -
Evolving Nutritional Therapy for Diabetes Mellitus
Uusitupa, Matti; Schwab, Ursula. 2020. Nutrients. 12: 423 -
Fatty acids in the de novo lipogenesis pathway and incidence of type 2 diabetes: A pooled analysis of prospective cohort studies
Imamura, Fumiaki; Fretts, Amanda M; Marklund, Matti; Ardisson Korat, Andres V; Yang, Wei-Sin; Lankinen, Maria; Qureshi, Waqas; Helmer, Catherine; Chen, Tzu-An; Virtanen, Jyrki K; Wong, Kerry; Bassett, Julie K; Murphy, Rachel; Tintle, Nathan; Yu, Chaoyu Ian; Brouwer, Ingeborg A; Chien, Kuo-Liong; Chen, Yun-Yu; Wood, Alexis C; Del Gobbo, Liana C et al [incl. Laakso, Markku; Tuomainen, Tomi-Pekka; Uusitupa, Matti]. 2020. PLoS medicine. 17: e1003102 -
Metformin and risk of Alzheimer's disease among community-dwelling people with diabetes: a national case-control study
Sluggett, JK; Koponen, M; Bell, JS; Taipale, H; Tanskanen, A; Tiihonen, J; Uusitupa, M; Tolppanen, AM; Hartikainen, S. 2020. Journal of clinical endocrinology and metabolism. 105: dgz234 -
The Effects of Different Quantities and Qualities of Protein Intake in People With Diabetes Mellitus
Pfeiffer, AFH; Pedersen, E; Schwab, U; Risérus, U; Aas, AM; Uusitupa, M; Thanopoulou, A; Kendall, C; Sievenpiper, JL; Kahleová, H; Rahélic, D; Salas-Salvadó, J; Gebauer, S; Hermansen, K. 2020. Nutrients. 12: 365 -
Tyypin 2 diabetesepidemia odottaa edelleen ratkaisuja
Uusitupa, Matti. 2020. Lääkärilehti. 75: 740 -
An Isocaloric Nordic Diet Modulates RELA and TNFRSF1A Gene Expression in Peripheral Blood Mononuclear Cells in Individuals with Metabolic Syndrome-A SYSDIET Sub-Study
Ulven, SM; Holven, KB; Rundblad, A; Myhrstad, MCW; Leder, L; Dahlman, I; Mello, VD; Schwab, U; Carlberg, C; Pihlajamäki, J; Hermansen, K; Dragsted, LO; Gunnarsdottir, I; Cloetens, L; Åkesson, B; Rosqvist, F; Hukkanen, J; Herzig, KH; Savolainen, MJ; Risérus, U; et al. [incl. Uusitupa, M]. 2019. Nutrients. 11: 2932 -
Associations of circulating very-long-chain saturated fatty acids and incident type 2 diabetes: a pooled analysis of prospective cohort studies
Fretts, AM; Imamura, F; Marklund, M; Micha, R; Wu, JHY; Murphy, RA; Chien, KL; McKnight, B; Tintle, N; Forouhi, NG; Qureshi, WT; Virtanen, JK; Wong, K; Wood, AC; Lankinen, M; Rajaobelina, K; Harris, TB; et al (incl; Laakso, M; Uusitupa, M; Voutilainen, S). 2019. American journal of clinical nutrition. 109: 1216-1223 -
Biomarkers of Dietary Omega-6 Fatty Acids and Incident Cardiovascular Disease and Mortality: An Individual-Level Pooled Analysis of 30 Cohort Studies
Marklund, M; Wu, JHY; Imamura,;F, Del Gobbo, LC; Fretts, A; de Goede, J; Shi, P; Tintle, N; Wennberg, M; Aslibekyan, S; Chen, TA; de Oliveira Otto, MC; Hirakawa, Y; Eriksen, HH; Kröger, J; Jaguzzi, F; Lankinen, M; Murphy, Rachel A; Prem, Kiesha; Samieri, Cécilia; et al. (incl. Uusitupa, M; Mursu J; Laakso, M; Virtanen, J). 2019. Circulation. 139: 2422-2436 -
Good news from the Da Qing Diabetes Prevention Outcome Study-healthy lifestyles result in long-term cardiovascular benefits
Uusitupa, Matti. 2019. Annals of translational medicine. 7: S368 -
Healthy Nordic Diet Modulates the Expression of Genes Related to Mitochondrial Function and Immune Response in Peripheral Blood Mononuclear Cells from Subjects with the Metabolic Syndrome - A SYSDIET Sub-Study
Myhrstad, MC; de Mello, VD; Dahlman, I; Kolehmainen, M; Paananen, J; Rundblad, A; Carlberg, C; Olstad, OK; Pihlajamäki, J; Holven, KB; Hermansen, K; Dragsted, LO; Gunnarsdottir, I; Cloetens, L; Storm, MU; Åkesson, B; Rosqvist, F; Hukkanen, J; et al. (incl. Schwab, U; Uusitupa, M). 2019. Molecular nutrition and food research. 63: 1801405 -
Kalaöljyt ja sydäntautien ehkäisy
Uusitupa, Matti; Schwab, Ursula. 2019. Duodecim. 135: 905-907 -
Life Style Intervention Improves Retinopathy Status - The Finnish Diabetes Prevention Study
Aro, A; Kauppinen, A; Kivinen, N; Selander, T; Kinnunen, K; Tuomilehto, J; Keinänen-Kiukaanniemi, S; Lindström, J; Uusitupa, M; Kaarniranta, K. 2019. Nutrients. 11: 1691 -
Nordic Diet and Inflammation - A Review of Observational and Intervention Studies
Lankinen, Maria; Uusitupa, Matti; Schwab, Ursula. 2019. Nutrients. 11: 1369 -
Prevention of Type 2 Diabetes by Lifestyle Changes: A Systematic Review and Meta-Analysis
Uusitupa, M; Khan, TA; Viguiliouk, E; Kahleova, H; Rivellese, AA; Hermansen, K; Pfeiffer, A; Thanopoulou, A; Salas-Salvadó, J; Schwab, U; Sievenpiper, JL. 2019. Nutrients. 11: 2611 -
Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution
Justice, AE; Karaderi, T; Highland, HM; Young, KL; Graff, M; Lu, Y; Turcot, V; Auer, PL; Fine, RS; Guo, X; Schurmann, C; Lempradl, A; Marouli, E; Mahajan, A; Winkler, TW; Locke, AE; Medina-Gomez, C; Esko, T; Vedantam, S; Giri, A; Lo, KS; et al. (Incl. Kuusisto, Johanna; Laakso, Markku; Lakko, Timo; Uusitupa, Matti; Vanhala, Mauno). 2019. Nature genetics. 51: 452-469 -
Quantitative assessment of betainized compounds and associations with dietary and metabolic biomarkers in the randomized study of the healthy Nordic diet (SYSDIET)
Tuomainen, M; Kärkkäinen, O; Leppänen, J; Auriola, S; Lehtonen, M; Savolainen, MJ; Hermansen, K; Risérus, U; Åkesson, B; Thorsdottir, I; Kolehmainen, M; Uusitupa, M; Poutanen, K; Schwab, U; Hanhineva, K. 2019. American journal of clinical nutrition. 110: 1108-1118 -
Associations of serum indolepropionic acid, a gut microbiota metabolite, with type 2 diabetes and low-grade inflammation in high-risk individuals
Tuomainen, Marjo; Lindström, Jaana; Lehtonen, Marko; Auriola, Seppo; Pihlajamäki, Jussi; Peltonen, Markku; Tuomilehto, Jaakko; Uusitupa, Matti; de Mello, Vanessa D; Hanhineva, Kati. 2018. Nutrition and diabetes. 8: 35 -
Diets rich in whole grains increase betainized compounds associated with glucose metabolism
Kärkkäinen, O; Lankinen, MA; Vitale, M; Jokkala, J; Leppänen, J; Koistinen, V; Lehtonen, M; Giacco, R; Rosa-Sibakov, N; Micard, V; Rivellese, AAA; Schwab, U; Mykkänen, H; Uusitupa, M; Kolehmainen, M; Riccardi, G; Poutanen, K; Auriola, S; Hanhineva, K. 2018. American journal of clinical nutrition. 108: 971-979 -
Early fecal microbiota composition in children who later develop celiac disease and associated autoimmunity
Rintala, A; Riikonen, I; Toivonen, A; Pietilä, S; Munukka, E; Pursiheimo, JP; Elo, LL; Arikoski, P; Luopajärvi, K; Schwab, U; Uusitupa, M; Heinonen, S; Savilahti, E; Eerola, E; Ilonen, J. 2018. Scandinavian journal of gastroenterology. 53: 403-409 -
Fatty acid biomarkers of dairy fat consumption and incidence of type 2 diabetes: A pooled analysis of prospective cohort studies
Imamura, F; Fretts, A; Marklund, M; Ardisson Korat, AV; Yang, WS; Lankinen, M; Qureshi, W; Helmer, C; Chen, TA; Wong, K; Bassett, JK; Murphy, R; Tintle, N; Yu, CI; Brouwer, IA; Chien, KL; Frazier-Wood, AC; Del Gobbo, LC; Djoussé, L; Geleijnse, JM; et al (incl. Lankinen, Maria; Laakso, Markku; Uusitupa, Matti). 2018. PLoS medicine. 15: e100267 -
Genes and Dietary Fatty Acids in Regulation of Fatty Acid Composition of Plasma and Erythrocyte Membrane
Lankinen, Maria; Uusitupa, Matti; Schwab, Ursula. 2018. Nutrients. 10: 1785 -
Keinotekoiset makeutteet
Uusitupa, Matti; Schwab, Ursula. 2018. Lääkärilehti. 73: 926-930 -
Prevention of type 2 diabetes - success story that is waiting for next steps
Uusitupa, Matti; Lindström, Jaana; Tuomilehto, Jaakko. 2018. European journal of clinical nutrition. 72: 1260-1266 -
Remission of type 2 diabetes : mission not impossible
Uusitupa, Matti. 2018. The Lancet. 391: 515-516 -
Serum Adiponectin/Ferritin Ratio in Relation to the Risk of Type 2 diabetes and Insulin Sensitivity
Aregbesola, A; de Mello, VDF; Lindström, J; Voutilainen, S; Virtanen, JK; Keinänen-Kiukaanniemi, S; Tuomainen, TP; Tuomilehto, J; Uusitupa, M. 2018. Diabetes research and clinical practice. 141: 264-274 -
Susceptibility of low-density lipoprotein particles to aggregate depends on particle lipidome, is modifiable, and associates with future cardiovascular deaths
Ruuth, M; Nguyen, SD; Vihervaara, T; Hilvo, M; Laajala, TD; Kondadi, PK; Gisterå, A; Lähteenmäki, H; Kittilä, T; Huusko, J; Uusitupa, M; Schwab, U; Savolainen, MJ; Sinisalo, J; Lokki, ML; Nieminen, MS; Jula, A; Perola, M; Ylä-Herttula, S; Rudel, L; et al.. 2018. European heart journal. 39: 2562-2573 -
Varhainen laihdutus voi kääntää tyypin 2 diabeteksen remissioon
Uusitupa, Matti; Mustajoki, Pertti. 2018. Lääkärilehti. 73: 825-825a -
A Low-Frequency Inactivating AKT2 Variant Enriched in the Finnish Population Is Associated With Fasting Insulin Levels and Type 2 Diabetes Risk
Manning A, Highland HM, Gasser J, Sim X, Tukiainen T, Fontanillas P, Grarup N, Rivas MA, Mahajan A, Locke AE, Cingolani P, Pers TH, Viñuela A, Brown AA, Wu Y, Flannick J, Fuchsberger C, Gamazon ER, Gaulton KJ, Im HK et al. (incl. Lakka Timo, Kuulasmaa Teemu, Laakso Markku, Uusitupa Matti). 2017. Diabetes. 66: 2019-2032 -
Alterations in fatty acid metabolism in response to obesity surgery combined with dietary counseling
Walle P, Takkunen M, Männistö V, Vaittinen M, Käkelä P, Ågren J, Schwab U, Lindström J, Tuomilehto J, Uusitupa M, Pihlajamäki J. 2017. Nutrition and diabetes. 7: e285 -
Fasting serum hippuric acid is elevated after bilberry (Vaccinium myrtillus) consumption and associates with improvement of fasting glucose levels and insulin secretion in persons at high risk of developing type 2 diabetes
de Mello VD, Lankinen MA, Lindström J, Puupponen-Pimiä R, Laaksonen DE, Pihlajamäki J, Lehtonen M, Uusitupa M, Tuomilehto J, Kolehmainen M, Törrönen R, Hanhineva K. 2017. Molecular nutrition and food research. 61: 1700019 -
Indolepropionic acid and novel lipid metabolites are associated with a lower risk of type 2 diabetes in the Finnish Diabetes Prevention Study
de Mello VD, Paananen J, Lindstrom J, Lankinen MA, Shi L, Kuusisto J, Pihlajamaki J, Auriola S, Lehtonen M, Rolandsson O, Bergdahl IA, Nordin E, Ilanne-Parikka P, Keinänen-Kiukaanniemi S, Landberg R, Eriksson JG, Tuomilehto J, Hanhineva K, Uusitupa M. 2017. Scientific reports. 7: 46337 -
Instability of LDL particles predicts future cardiovascular deaths
Ruuth M, Nguyen SD, Vihervaara T, Hilvo M, Laajala TD, Kondadi PK, Anton G, Huusko J, Uusitupa M, Schwab U, Lawrence R, Ketelhuth D, Laaksonen R, Baumann M, Aittokallio T, Jauhiainen M, Jan B, Williams KJ, Kovanen P, Öörni K. 2017. Atherosclerosis -
Painopiste preventioon!
Uusitupa Matti, Rautalahti Matti, Vartiainen Erkki. 2017. Duodecim. 133: 1125-1126 -
Potkiiko SOTE myös liikkumaan
Uusitupa Matti. 2017. Liikunta ja tiede. 54: 42-44 -
Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity
Turcot V, Lu Y, Highland HM, Schurmann C, Justice AE, Fine RS, Bradfield JP, Esko T, Giri A, Graff M, Guo X, Hendricks AE, Karaderi T, Lempradl A, Locke AE, Mahajan A, Marouli E, Sivapalaratnam S, Young KL, Alfred T et al. (incl. Laakso Markku, Lakka Timo, Uusitupa Matti). 2017. Nature genetics. 50; 2018: 26-41 -
A Healthy Nordic Diet Alters the Plasma Lipidomic Profile in Adults with Features of Metabolic Syndrome in a Multicenter Randomized Dietary Intervention
Lankinen Maria, Schwab Ursula, Kolehmainen Marjukka, Paananen Jussi, Nygren Heli, Seppänen-Laakso Tuulikki, Poutanen Kaisa, Hyötyläinen Tuulia, Risérus Ulf, Savolainen Markku J, Hukkanen Janne, Brader Lea, Marklund Matti, Rosqvist Fredrik, Hermansen Kjeld, Cloetens Lieselotte, Önning Gunilla, Thorsdottir Inga, Gunnarsdottir Ingibjork, Åkesson Björn et al. 2016. Journal of nutrition. 146: 662-672 -
A principal component meta-analysis on multiple anthropometric traits identifies novel loci for body shape
Ried JS, Jeff M J, Chu AY, Bragg-Gresham JL, van Dongen J, Huffman JE, Ahluwalia TS, Cadby G, Eklund N, Eriksson J, Esko T, Feitosa MF, Goel A, Gorski M, Hayward C, Heard-Costa NL, Jackson AU, Jokinen E, Kanoni S, Kristiansson K et al. 2016. Nature communications. 7: 13357 -
Association of long-term dietary fat intake, exercise, and weight with later cognitive function in the Finnish Diabetes Prevention Study
Lehtisalo J, Lindström J, Ngandu T, Kivipelto M, Ahtiluoto S, Ilanne-Parikka P, Keinänen-Kiukaanniemi S, Eriksson JG, Uusitupa M, Tuomilehto J, Luchsinger J. 2016. Journal of nutrition health and aging. 20: 146-154 -
Correction: The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study
Winkler Thomas W, Justice Anne E, Graff Mariaelisa, Barata Llilda, Feitosa Mary F, Chu Su, Czajkowski Jacek, Esko Tõnu, Fall Tove, Kilpeläinen Tuomas O, Lu Yingchang, Mägi Reedik, Mihailov Evelin, Pers Tune H, Rüeger Sina, Teumer Alexander, Ehret Georg B, Ferreira Teresa, Heard-Costa Nancy L, Karjalainen Juha et al. 2016. PLoS genetics. 12: e1006166 -
Effects of a healthy Nordic diet on gene expression changes in peripheral blood mononuclear cells in response to an oral glucose tolerance test in subjects with metabolic syndrome: a SYSDIET sub-study
Leder Lena, Kolehmainen Marjukka, Narverud Ingunn, Dahlman Ingrid, Myhrstad Mari CW, de Mello Vanessa D, Paananen Jussi, Carlberg Castren, Schwab Ursula, Herzig Karl-Heinz, Cloetens Lieselotte, Storm Matilda Ulmius, Hukkanen Janne, Savolainen Markku J, Rosqvist Fredrik, Hermansen Kjeld, Dragsted Lars O, Gunnarsdottir Ingibjörk, Thorsdottir Inga, Risérus Ulf et al.. 2016. Genes and nutrition. 11: 1-13 -
Evidence for three genetic loci involved in both anorexia nervosa risk and variation of body mass index
Hinney A, Kesselmeier M, Jall S, Volckmar AL, Föcker M, Antel J, Heid IM, Winkler TW, Grant SF, Guo Y, Bergen AW, Kaye W, Berrettini W, Hakonarson H, Herpertz-Dahlmann B, de Zwaan M, Herzog W, Ehrlich S, Zipfel S, Egberts KM et al., GCAN, WTCCC3, EGG, GIANT, Price Foundation Collaborative Group, Children's Hospital of Philadelphia/Price Foundation. 2016. Molecular psychiatry. 2017; 22: 192-201 -
FTO genotype and weight loss: systematic review and meta-analysis of 9563 individual participant data from eight randomised controlled trials
Livingstone KM, Celis-Morales C, Papandonatos GD, Erar B, Florez JC, Jablonski KA, Razquin C, Marti A, Heianza Y, Huang T, Sacks FM, Svendstrup M, Sui X, Church TS, Jääskeläinen T, Lindström J, Tuomilehto J, Uusitupa M, Rankinen T, Saris WH et al.. 2016. BMJ. 354: i4707 -
Following in the Footsteps of the North Karelia Project: Prevention of Type 2 Diabetes
Lindström Jaana, Uusitupa Matti, Tuomilehto Jaakko, Peltonen Markku. 2016. Global heart. 11: 223-228 -
Hälsofrämjande nordiska kostvanor - senaste framstegen och framtida forskningsutmaningar
Uusitupa Matti. 2016. Nordisk Nutrition. : 27-30 -
Lifestyle changes and cardiovascular risk reduction in diabetes
Uusitupa Matti. 2016. The Lancet Diabetes & Endocrinology. 4: 877-878 -
Liikuntalääketiede nyt!
Uusitupa, Matti. 2016. Liikunta ja tiede. 53: 83 -
Liikuntalääketieteen yhteiskunnallisen merkityksen ja liikuntalääketieteen keskusten toiminnan arviointi (2006 - 2016)
Uusitupa Matti. 2016. Valtion liikuntaneuvoston julkaisuja. . -
Rare variant in scavenger receptor BI raises HDL cholesterol and increases risk of coronary heart disease
Zanoni Paolo, Khetarpal Sumeet A, Larach Daniel B, Hancock-Cerutti William F, Millar John S, Cuchel Marina, DerOhannessian Stephanie, Kontush Anatol, Surendran Praveen, Saleheen Danish, Trompet Stella, Jukema J Wouter, De Craen Anton, Deloukas Panos, Sattar Naveed, Ford Ian, Packard Chris, Majumder Abdullah al Shafi , Alam Dewan S, Di Angelantonio Emanuele et al. 2016. Science. 351: 1166-1171 -
The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals
Ehret GB, Ferreira T, Chasman DI, Jackson AU, Schmidt EM, Johnson T, Thorleifsson G, Luan J, Donnelly LA, Kanoni S, Petersen AK, Pihur V, Strawbridge RJ, Shungin D, Hughes MF, Meirelles O, Kaakinen M, Bouatia-Naji N, Kristiansson K, Shah S et al.. 2016. Nature genetics. 48: 1171-1184 -
Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension
Surendran P, Drenos F, Young R, Warren H, Cook JP, Manning AK, Grarup N, Sim X, Barnes DR, Witkowska K, Staley JR, Tragante V, Tukiainen T, Yaghootkar H, Masca N, Freitag DF, Ferreira T, Giannakopoulou O, Tinker A, Harakalova M et al. 2016. Nature genetics. 48: 1151-1161 -
Alkylresorcinols in adipose tissue biopsies as biomarkers of whole-grain intake: an exploratory study of responsiveness to advised intake over 12 weeks
Wu H, Kolehmainen M, Mykkänen H, Poutanen K, Uusitupa M, Schwab U, Wolk A, Landberg R. 2015. European journal of clinical nutrition. 69: 1244-1248 -
Biological interpretation of genome-wide association studies using predicted gene functions
Pers Tune H, Karjalainen Juha M, Chan Yingleong, Westra Harm-Jan, Wood Andrew R, Yang Jian, Lui Julian C, Vedantam Sailaja, Gustafsson Stefan, Esko Tonu, Frayling Tim, Speliotes Elizabeth K, Genetic Investigation of ANthropometric Traits (GIANT) Consortium (incl. Johanna Kuusisto, Markku Laakso, Timo Lakka, Matti Uusitupa), Boehnke Michael, Raychaudhuri Soumya, Fehrmann Rudolf SN, Hirschhorn Joel N, Franke Lude. 2015. Nature communications. 6: 5890 -
CMPF Does Not Associate with Impaired Glucose Metabolism in Individuals with Features of Metabolic Syndrome
Lankinen Maria A., Hanhineva Kati, Kolehmainen Marjukka, Lehtonen Marko, Auriola Seppo, Mykkänen Hannu, Poutanen Kaisa, Schwab Ursula, Uusitupa Matti. 2015. PLoS ONE. 10: e0124379 -
Changes in glucose metabolism in people with different glucose metabolism disorders at baseline: follow-up results of a Finnish national diabetes prevention programme
Rautio N, Jokelainen J, Oksa H, Saaristo T, Peltonen M, Puolijoki H, Tuomilehto J, Vanhala M, Moilanen L, Uusitupa M, Keinänen-Kiukaanniemi S. 2015. Diabetic medicine. [epub ahead of print 8 May 2015]: - -
Cognition in the Finnish Diabetes Prevention Study
Luchsinger José A, Lehtisalo Jenni, Lindström Jaana, Ngandu Tiia, Kivipelto Miia, Ahtiluoto Satu, Ilanne-Parikka Pirjo, Keinänen-Kiukaanniemi Sirkka, Eriksson Johan G, Uusitupa Matti, Tuomilehto Jaakko, for the Finnish Diabetes Prevention Study (DPS). 2015. Diabetes research and clinical practice. 108: e63-e66 -
Development of gliadin-specific immune responses in children with HLA-associated genetic risk for celiac disease
Lammi Anne, Arikoski Pekka, Hakulinen Arja, Schwab Ursula, Uusitupa Matti, Heinonen Seppo, Savilahti Erkki, Kinnunen Tuure, Ilonen Jorma. 2015. Scandinavian journal of gastroenterology. 2016; 51: 168-177 -
Diabetes, glycaemia, and cognition - a secondary analysis of the Finnish Diabetes Prevention Study
Lehtisalo Jenni, Lindström Jaana, Ngandu Tiia, Kivipelto Miia, Ahtiluoto Satu, Ilanne-Parikka Pirjo, Keinänen-Kiukaanniemi Sirkka, Eriksson Johan G., Uusitupa Matti, Tuomilehto Jaakko, Luchsinger Jose A, for the Finnish Diabetes Prevention Study (DPS). 2015. Diabetes/metabolism research and reviews. [epub ahead of print 18 AUG 2015]: - -
Diet heart controversies - Quality of fat matters
Schwab Ursula, Uusitupa Matti. 2015. Nutrition metabolism and cardiovascular diseases. 25: 617-622 -
Dietary polyunsaturated fatty acids and the Pro12Ala polymorphisms of PPARG regulate serum lipids through divergent pathways: a randomized crossover clinical trial
Pihlajamäki Jussi, Schwab Ursula, Kaminska Dorota, Ågren Jyrki, Kuusisto Johanna, Kolehmainen Marjukka, Paananen Jussi, Laakso Markku, Uusitupa Matti. 2015. Genes and nutrition. 10: 43 -
Gene-diet interaction of a common FADS1 variant with marine polyunsaturated fatty acids for fatty acid composition in plasma and erythrocytes among men
Takkunen Markus J, de Mello Vanessa D, Schwab Ursula S, Kuusisto Johanna, Vaittinen Maija, Ågren Jyrki J, Laakso Markku, Pihlajamäki Jussi, Uusitupa MI. 2015. Molecular nutrition and food research. 2016; 60: 381-389 -
Genetic studies of body mass index yield new insights for obesity biology
Locke Adam E, Kahali Bratati, Berndt Sonja I, Justice Anne E, Pers Tune H, Day Felix R, Powell Corey, Vedantam Sailaja, Buchkovich Martin L, Yang Jian, Croteau-Chonka Damien C, Esko Tonu, Fall Tove, Ferreira Teresa, Gustafsson Stefan, Kutalik Zoltán, Luan Jian'an, Mägi Reedik, Randall Joshua C, Winkler Thomas W et al. 2015. Nature. 518: 197-206 -
Glucose Metabolism Effects of Vitamin D in Prediabetes: the VitDmet Randomized Placebo-Controlled Supplementation Study
Tuomainen Tomi-Pekka, Virtanen Jyrki K, Voutilainen Sari, Nurmi Tarja, Mursu Jaakko, de Mello Vanessa DF, Schwab Ursula, Hakumäki Martti, Pulkki Kari, Uusitupa Matti. 2015. Journal of Diabetes Research. 2015: 8 pages -
Identification and functional characterization of G6PC2 coding variants influencing glycemic traits define an effector transcript at the G6PC2-ABCB11 locus
Mahajan Anubha, Sim Xueling, Ng Hui Jin, Manning Alisa, Rivas Manuel A, Highland Heather M, Locke Adam E, Grarup Niels, Im Hae Kyung, Cingolani Pablo, Flannick Jason, Fontanillas Pierre, Fuchsberger Christian, Gaulton Kyle J, Teslovich Tanya M, Rayner N William, Robertson Neil R, Beer Nicola L, Rundle Jana K, Bork-Jensen Jette et al. On Behalf of the T2D-GENES consortium and GoT2D consortium. 2015. PLoS genetics. 11: e1004876 -
Is the adiposity-associated FTO gene variant related to all-cause mortality independent of adiposity? Meta-analysis of data from 169,551 Caucasian adults
Zimmermann E, Angquist LH, Mirza SS, Zhao JH, Chasman DI, Fischer K, Qi Q, Smith AV, Thinggaard M, Jarczok MN, Nalls MA, Trompet S, Timpson NJ, Schmidt B, Jackson AU, Lyytikäinen LP, Verweij N, Mueller-Nurasyid M, Vikström M et al. 2015. Obesity reviews. 16: 327-340 -
Longitudinal associations of serum fatty acid composition with type 2 diabetes risk and markers of insulin secretion and sensitivity in the Finnish Diabetes Prevention Study
Takkunen Markus J, Schwab Ursula S, de Mello Vanessa DF, Eriksson Johan G, Lindström Jaana, Tuomilehto Jaakko, Uusitupa Matti IJ, the DPS Study Group. 2015. European journal of nutrition. 2016; 55: 967-979 -
MFAP5 is Related to Obesity-Associated Adipose Tissue and Extracellular Matrix Remodeling and Inflammation
Vaittinen Maija, Kolehmainen Marjukka, Rydén Mikael, Eskelinen Matti, Wabitsch Martin, Pihlajamäki Jussi, Uusitupa Matti, Pulkkinen Leena. 2015. Obesity. 23: 1371-1378 -
Markers of cholesterol metabolism as biomarkers in predicting diabetes in the Finnish Diabetes Prevention Study
de Mello VDF, Lindström J, Eriksson JG, Ilanne-Parikka P, Keinänen-Kiukaanniemi S, Pihlajamäki J, Tuomilehto J, Uusitupa M. 2015. Nutrition metabolism and cardiovascular diseases. 25: 635-642 -
National diabetes prevention program (DEHKO): awareness and self-reported lifestyle changes in Finnish middle-aged population
Wikström K, Lindström J, Tuomilehto J, Saaristo TE, Helakorpi S, Korpi-Hyövälti E, Oksa H, Vanhala M, Keinänen-Kiukaanniemi S, Uusitupa M, Peltonen M. 2015. Public health. 129: 210-217 -
New genetic loci link adipose and insulin biology to body fat distribution
Shungin Dmitry, Winkler Thomas W, Croteau-Chonka Damien C, Ferreira Teresa, Locke Adam E, Mägi Reedik, Strawbridge Rona J, Pers Tune H, Fischer Krista, Justice Anne E, Workalemahu Tsegaselassie, Wu Joseph MW, Buchkovich Martin L, Heard-Costa Nancy L, Roman Tamara S, Drong Alexander W, Song Ci, Gustafsson Stefan, Day Felix R, Esko Tonu et al. 2015. Nature. 518: 187-196 -
Plasma fatty acids as predictors of glycaemia and type 2 diabetes
Lankinen Maria A, Stancáková Alena, Uusitupa Matti, Ågren Jyrki, Pihlajamäki Jussi, Kuusisto Johanna, Schwab Ursula, Laakso Markku. 2015. Diabetologia. 58: 2533-2544 -
Relevance of Vitamin D Receptor Target Genes for Monitoring the Vitamin D Responsiveness of Primary Human Cells
Vukic Maja, Neme Antonio, Seuter Sabine, Saksa Noora, de Mello Vanessa DF, Nurmi Tarja, Uusitupa Matti, Tuomainen Tomi-Pekka, Virtanen Jyrki K, Carlberg Carsten. 2015. PLoS ONE. 10: e0124339 -
Suomalaisen ravitsemustutkimuksen tähtihetkiä
Uusitpa Matti. 2015. Duodecim. 131: 1865-1871 -
The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study
Winkler Thomas W, Justice Anne E, Graff Mariaelisa, Barata Llilda, Feitosa Mary F, Chu Su, Czajkowski Jacek, Esko Tõnu, Fall Tove, Kilpeläinen Tuomas O, Lu Yingchang, Mägi Reedik, Mihailov Evelin, Pers Tune H, Rüeger Sina, Teumer Alexander, Ehret Georg B, Ferreira Teresa, Heard-Costa Nancy L, Karjalainen Juha et al. 2015. PLoS genetics. 11: e1005378 -
A dietary biomarker approach captures compliance and cardiometabolic effects of a healthy nordic diet in individuals with metabolic syndrome
Marklund Matti, Magnusdottir Ola K, Rosqvist Fredrik, Cloetens Lieselotte, Landberg Rikard, Kolehmainen Marjukka, Brader Lea, Hermansen Kjeld, Poutanen Kaisa S, Herzig Karl-Heinz, Hukkanen Janne, Savolainen Markku J, Dragsted Lars O, Schwab Ursula, Paananen Jussi, Uusitupa Matti, Åkesson Björn, Thorsdottir Inga, Risérus Ulf. 2014. Journal of nutrition. 144: 1642-1649 -
ADAMTS9 locus associates with increased risk of wet AMD
Helisalmi Seppo, Immonen Ilkka, Losonczy Gergely, Resch Miklos D, Benedek Szabolcs, Balogh Istvan, Papp Andras, Berta Andras, Uusitupa Matti, Hiltunen Mikko, Kaarniranta Kai. 2014. Acta ophthalmologica. 2014: 1 -
Assessment of Body Composition in Subjects with Metabolic Syndrome Comparing Single-Frequency Bioelectrical Impedance Analysis and Bioelectrical Spectroscopy
Cloetens Lieselotte, Johansson-Persson Anna, Helgegren Hannah, Landin-Olsson Mona, Uusitupa Matti, Åkesson Björn, Önning Gunilla. 2014. Metabolic syndrome and related disorders. Epub ahead of print: - -
Association of serum 25-hydroxyvitamin D with lifestyle factors and metabolic and cardiovascular disease markers: population-based cross-sectional study (FIN-D2D)
Miettinen Maija E, Kinnunen Leena, Leiviskä Jaana, Keinänen-Kiukaanniemi Sirkka, Korpi-Hyövälti Eeva, Niskanen Leo, Oksa Heikki, Saaristo Timo, Tuomilehto Jaakko, Vanhala Mauno, Uusitupa Matti, Peltonen Markku. 2014. PLoS ONE. 9: e100235 -
Associations of erythrocyte membrane fatty acids with the concentrations of C-reactive protein, interleukin 1 receptor antagonist and adiponectin in1373 men
Takkunen MJ, de Mello VDF, Schwab US, Ågren JJ, Kuusisto J, Uusitupa MIJ. 2014. Prostaglandins leukotrienes and essential fatty acids. 91: 169-174 -
Changes in lifestyle modestly reduce the estimated cardiovascular disease risk in one-year follow-up of the Finnish diabetes prevention program (FIN-D2D)
Rautio N, Jokelainen J, Pölönen A, Oksa H, Peltonen M, Vanhala M, Puolijoki H, Moilanen L, Tuomilehto J, Uusitupa M, Keinänen-Kiukaanniemi S, Saaristo T. 2014. European journal of cardiovascular nursing. Epub ahead of print: - -
Changes in vitamin D target gene expression in adipose tissue monitor the vitamin D response of human individuals
Ryynänen Jussi, Neme Antonio, Tuomainen Tomi-Pekka, Virtanen Jyrki K, Voutilainen Sari, Nurmi Tarja, de Mello Vanessa DF, Uusitupa Matti, Carlberg Carsten. 2014. Molecular nutrition and food research. 58: 2036-2045 -
DNA methylation in obesity and type 2 diabetes
de Mello Vanessa Derenji Ferreira, Pulkkinen Leena, Lalli Marianne, Kolehmainen Marjukka, Pihlajamäki Jussi, Uusitupa Matti. 2014. Annals of medicine. 46: 103-113 -
Defining the role of common variation in the genomic and biological architecture of adult human height
Wood Andrew R, Esko Tonu, Yang Jian, Vedantam Sailaja, Pers Tune H, Gustafsson Stefan, Chu Audrey Y, Estrada Karol, Luan Jian'an, Kutalik Zoltán, Amin Najaf, Buchkovich Martin L, Croteau-Chonka Damien C, Day Felix R, Duan Yanan, Fall Tove, Fehrmann Rudolf, Ferreira Teresa, Jackson Anne U, Karjalainen Juha et.al.. 2014. Nature genetics. 46: 1173-86 -
Diabetesepidemia on vielä ehkäistävissä
Uusitupa Matti, Lindström Jaana, Tuomilehto Jaakko. 2014. Lääkärilehti. 69: 1454-1455 -
Dissecting high from low responders in a vitamin D3 intervention study
Saksa Noora, Neme Antonio, Ryynänen Jussi, Uusitupa Matti, de Mello Vanessa DF, Voutilainen Sari, Nurmi Tarja, Virtanen Jyrki K, Tuomainen Tomi-Pekka, Carlberg Carsten. 2014. Journal of steroid biochemistry and molecular biology. Epub ahead of print: - -
Effect of the amount and type of dietary fat on cardiometabolic risk factors and risk of developing type-2 diabetes, cardiovascular disease, and cancer: a systematic review
Schwab Ursula, Lauritzen Lotte, Tholstrup Tine, Haldorsson Thorhallur I, Riserus Ulf, Uusitupa Matti, Becker Wulf. 2014. Food and nutrition research. 58: - -
Effects of a healthy Nordic diet on plasma 25-hydroxyvitamin D concentration in subjects with metabolic syndrome: a randomized, placebo-controlled trial (SYSDIET)
Brader Lea, Rejnmark Lars, Carlberg Carsten, Schwab Ursula, Kolehmainen Marjukka, Rosqvist Fredrik, Cloetens Lieselotte, Landin-Olsson Mona, Gunnarsdottir Ingibjorg, Poutanen Kaisa S, Herzig Karl-Heinz, Risérus Ulf, Savolainen Markku J, Thorsdottir Inga, Uusitupa Matti, Hermansen Kjeld. 2014. European journal of nutrition. 53: 1123-34 -
Effects of whole grain, fish and bilberries on serum metabolic profile and lipid transfer protein activities: a randomized trial (Sysdimet)
Lankinen Maria, Kolehmainen Marjukka, Jääskeläinen Tiina, Paananen Jussi, Joukamo Laura, Kangas Antti J, Soininen Pasi, Poutanen Kaisa, Mykkänen Hannu, Gylling Helena, Ore¨ic Matej, Jauhiainen Matti, Ala-Korpela Mika, Uusitupa Matti, Schwab Ursula. 2014. PLoS ONE. 9: e90352 -
FTO genetic variants, dietary intake and body mass index: insights from 177 330 individuals
Qi Qibin, Kilpeläinen Tuomas O, Downer Mary K, Tanaka Toshiko, Smith Caren E, Sluijs Ivonne, Sonerstedt Emily, Chu Audrey Y, Renström Frida, Lin Xiaochen, Ängquist Lars H, Huang Jinyan, Liu Zhonghua, Li Yanping, Asif Ali Muhammad, Xu Min, Singh Ahluwalia Tarunweer, Boer Jolanda MA, Chen Peng, Daimon Makoto et.al.. 2014. Human molecular genetics. Epub ahead of print: - -
Genome-wide Enrichment Analysis between Endometriosis and Obesity-related Traits Reveals Novel Susceptibility Loci
Rahmioglu Nilufer, Macgregor Stuart, Drong Alexander W, Hedman Åsa K, Harris Holly R, Randall Joshua C, Prokopenko Inga, The International EndoGene Consortium (IEC), The GIANT Consortium, Nyholt Dale R, Morris Andrew P, Montgomery Grant W, Missmer Stacey A, Lindgren Cecilia M, Zondervan Krina T. 2014. Human molecular genetics. Epub ahead of print: - -
Healthy Nordic diet downregulates the expression of genes involved in inflammation in subcutaneous adipose tissue in individuals with features of the metabolic syndrome
Kolehmainen Marjukka, Ulven Stine M, Paananen Jussi, de Mello Vanessa, Schwab Ursula, Carlberg Carsten, Myhrstad Mari, Pihlajamäki Jussi, Dungner Elisabeth, Sjölin Eva, Gunnarsdottir Ingibjörg, Cloetens Lieselotte, Landin-Olsson Mona, Akesson Björn, Rosqvist Fredrik, Hukkanen Janne, Herzig Karl-Heinz, Dragsted Lars O, Savolainen Markku J, Brader Lea, Hermansen Kjeld, Risérus Ulf, Thorsdottir Inga, Poutanen Kaisa S, Uusitupa Matti, Arner Peter, Dahlman Ingrid. 2014. American journal of clinical nutrition. 101: 228-239 -
Lifestyle Changes Aiming at Weight Loss Should Always Be Included in the Treatment of Obese Patients with Obstructive Sleep Apnea
Tuomilehto Henri, Uusitupa Matti. 2014. Sleep. 37: 1021 -
Lifestyle intervention in prevention of type 2 diabetes in women with a history of gestational diabetes mellitus: one-year results of the FIN-D2D project
Rautio Nina, Jokelainen Jari, Korpi-Hyövälti Eeva, Oksa Heikki, Saaristo Timo, Peltonen Markku, Moilanen Leena, Vanhala Mauno, Uusitupa Matti, Tuomilehto Jaakko, Keinänen-Kiukaanniemi Sirkka. 2014. Journal of womens health. 23: 506-12 -
Nontargeted metabolite profiling discriminates diet-specific biomarkers for consumption of whole grains, fatty fish, and bilberries in a randomized controlled trial
Hanhineva Kati, Lankinen Maria A, Pedret Anna, Schwab Ursula, Kolehmainen Marjukka, Paananen Jussi, de Mello Vanessa, Sola Rosa, Lehtonen Marko, Poutanen Kaisa, Uusitupa Matti, Mykkänen Hannu. 2014. Journal of nutrition. 2015; 145: 7-17 -
Novel approach identifies SNPs in SLC2A10 and KCNK9 with evidence for parent-of-origin effect on body mass index
Hoggart Clive J, Venturini Giulia, Mangino Massimo, Gomez Felicia, Ascari Giulia, Zhao Jing Hua, Teumer Alexander, Winkler Thomas W, T¨ernikova Natalia, Luan Jian'an, Mihailov Evelin, Ehret Georg B, Zhang Weihua, Lamparter David, Esko Tõnu, Macé Aurelian, Rüeger Sina, Bochud Pierre-Yves, Barcella Matteo, Dauvilliers Yves et al (including Atalay Mustafa, Kuusisto Johanna, Lakka Timo, Yaluri Alena, Laakso Markku, Uusitupa Matti). 2014. PLoS genetics. 10: e1004508 -
Plasma alkylresorcinols C17:0/C21:0 ratio, a biomarker of relative whole-grain rye intake, is associated to insulin sensitivity: a randomized study
Magnusdottir OK, Landberg R, Gunnarsdottir I, Cloetens L, Åkesson B, Landin-Olsson M, Rosqvist F, Iggman D, Schwab U, Herzig K-H, Savolainen MJ, Brader L, Hermansen K, Kolehmainen M, Poutanen K, Uusitupa M, Thorsdottir I, Risérus U. 2014. European journal of clinical nutrition. 68: 453-458 -
Primary vitamin D receptor target genes as biomarkers for the vitamin D3 status in the hematopoietic system
Wilfinger Julia, Seuter Sabine, Tuomainen Tomi-Pekka, Virtanen Jyrki K, Voutilainen Sari, Nurmi Tarja, de Mello Vanessa DF, Uusitupa Matti, Carlberg Carsten. 2014. Journal of nutritional biochemistry. 25: 875-884 -
Quality control and conduct of genome-wide association meta-analyses
Winkler Thomas W, Day Felix R, Croteau-Chonka Damien C, Wood Andrew R, Locke Adam E, Mägi Reedik, Ferreira Teresa, Fall Tove, Graff Mariaelisa, Justice Anne E, Luan Jian'an, Gustafsson Stefan, Randall Joshua C, Vedantam Sailaja, Workalemahu Tsegaselassie, Kilpeläinen Tuomas O, Scherag André, Esko Tonu, Kutalik Zoltán, Heid Iris M, The Genetic Investigation of Anthropometric Traits (GIANT) Consortium et al. (including Atalay Mustafa, Kuusisto Johanna, Laakso Markku, Yaluri Alena). 2014. Nature physics. 9: 1192-1212 -
Ruokavalio ja lievä tulehdus
Uusitupa Matti, Schwab Ursula. 2014. Duodecim. 130: 9-11 -
The Association between HbA1c, Fasting Glucose, 1-Hour Glucose and 2-Hour Glucose during an Oral Glucose Tolerance Test and Cardiovascular Disease in Individuals with Elevated Risk for Diabetes
Lind Marcus, Tuomilehto Jaakko, Uusitupa Matti, Nerman Olle, Eriksson Johan, Ilanne-Parikka Pirjo, Keinänen-Kiukaanniemi Sirkka, Peltonen Markku, Pivodic Aldina, Lindström Jaana. 2014. PLoS ONE. 9: e109506 -
The impact of weight reduction in the prevention of the progression of obstructive sleep apnea: an explanatory analysis of a 5-year observational follow-up trial
Tuomilehto Henri, Seppä Juha, Uusitupa Matti, Peltonen Markku, Martikainen Tarja, Sahlman Johanna, Kokkarinen Jouko, Randell Jukka, Pukkila Matti, Vanninen Esko, Tuomilehto Jaakko, Gylling Helena. 2014. Sleep medicine. 15: 329-335 -
The prevalence of metabolic syndrome and metabolically healthy obesity in Europe: a collaborative analysis of ten large cohort studies
van Vliet-Ostaptchouk Jana V, Nuotio Marja-Liisa, Slagter Sandra N, Doiron Dany, Fischer Krista, Foco Luisa, Gaye Amadou, Gögele Martin, Heier Margit, Hiekkalinna Tero, Joensuu Anni, Newby Christopher, Pang Chao, Partinen Eemil, Reischl Eva, Schwienbacher Christine, Tammesoo Mari-Liis, Swertz Morris A, Burton Paul, Ferretti Vincent et.al.. 2014. Bmc endocrine disorders. 14: 1-13 -
Whole grain rye intake, reflected by a biomarker, is associated with favorable blood lipid outcomes in subjects with the metabolic syndrome - a randomized study
Magnusdottir Ola Kally, Landberg Rikard, Gunnarsdottir Ingibjorg, Cloetens Lieselotte, Åkesson Björn, Rosqvist Fredrik, Schwab Ursula, Herzig Karl-Heinz, Hukkanen Janne, Savolainen Markku J, Brader Lea, Hermansen Kjeld, Kolehmainen Marjukka, Poutanen Kaisa, Uusitupa Matti, Risérus Ulf, Thorsdottir Inga. 2014. PLoS ONE. 9: e110827 -
Adherence to the Nordic Nutrition Recommendations in a Nordic population with metabolic syndrome: high salt consumption and low dietary fibre intake (The SYSDIET study)
Jonsdottir SE, Brader L, Gunnarsdottir I, Magnusdottir OK, Schwab U, Kolehmainen M, Risérus U, Herzig K-H, Cloetens L, Helgegren H, Johansson-Persson A, Hukkanen J, Poutanen K, Uusitupa M, Hermansen K, Thorsdottir I. 2013. Food and nutrition research. 57: 21391 -
Alkylresorcinols and A-carotene in plasma as dietary biomarkers for healthy nordic diet
Magnusdottir OK, Landberg R, Gunnarsdottir I, Cloetens L, Åkesson B, Önning G, Jonsdottir SE, Rosqvist F, Schwab U, Herzig KH, Savolainen MJ, Brader L, Hermansen K, Kolehmainen M, Poutanen K, Uusitupa M, Thorsdottir I, Risérus U. 2013. Annals of nutrition and metabolism. 63: 459 -
Association of erythrocyte membrane fatty acids with changes in glycemia and risk of type 2 diabetes
Mahendran Y, Ågren J, Uusitupa M, Cederberg H, Vangipurapu J, Stancakova A, Schwab U, Kuusisto J, Laakso M. 2013. American journal of clinical nutrition. -: - -
Common variants associated with plasma triglycerides and risk for coronary artery disease
Do R, Willer CJ, Schmidt EM, Sengupta S, Gao C, Peloso GM, Gustafsson S, Kanoni S, Ganna A, Chen J, Buchkovich ML, Mora S, Beckmann JS, Bragg-Gresham JL, Chang H-Y, Demirkan A, Den Hertog HM, Donnelly LA, Ehret GB, Esko T et.al.. 2013. Nature genetics. 45: 1345-52 -
D-vitamiinin puutos on yleistä suomalaisessa aikuisväestössä - D2D-väestötutkimus 2007
Miettinen M, Kinnunen L, Keinänen-Kiukaanniemi S, Korpi-Hyövälti E, Niskanen L, Oksa H, Saaristo T, Sundvall J, Tuomilehto J, Vanhala M, Uusitupa M, Peltonen M. 2013. Lääkärilehti. 68: 211-15 -
Diet, inflammation and prediabetes - impact of quality of diet
Uusitupa M, Schwab U. 2013. Canadian journal of diabetes. 37: 327-331 -
Dietary fat in relation to erythrocyte fatty acid composition in men
Takkunen M, Ågren J, Kuusisto J, Laakso M, Uusitupa M, Schwab U. 2013. Lipids. 48: 1093-1102 -
Discovery and refinement of loci associated with lipid levels
Willer CJ, Schmidt EM, Sengupta S, Peloso GM, Gustafsson S, Kanoni S, Ganna A, Chen J, Buchkovich ML, Mora S, Beckmann JS, Bragg-Gresham JL, Chang H-Y, Demirkan A, Den Hertog HM, Do R, Donnelly LA, Ehret GB, Esko T, Feitosa MF et.al.. 2013. Nature genetics. 45: 1274-1283 -
Do depressive symptoms have an impact on the effectiveness of lifestyle counseling in prevention of type 2 diabetes? One-year follow-up of FIN-D2D
Rautio N, Jokelainen J, Oksa H, Saaristo T, Moilanen L, Vanhala M, Peltonen M, Korpi-Hyövälti E, Tuomilehto J, Uusitupa M, Timonen M, Keinänen-Kiukaanniemi S. 2013. Primary care diabetes. -: - -
Downregulation of CPPED1 expression improves glucose metabolism in vitro in adipocytes
Vaittinen M, Kaminska D, Käkelä P, Eskelinen M, Kolehmainen M, Pihlajamäki J, Uusitupa M, Pulkkinen L. 2013. Diabetes. 62: 3747-3750 -
Effect of fatty and lean fish intake on lipoprotein subclasses in subjects with coronary heart disease: A controlled trial
Erkkilä AT, Schwab US, Lehto S, de Mello VD, Kangas AJ, Soininen P, Ala-Korpela M, Uusitupa MIJ. 2013. Journal of clinical lipidology. online: - -
Effects of an isocaloric healthy Nordic diet on ambulatory blood pressure in metabolic syndrome: a randomized SYSDIET sub-study
Brader L, Uusitupa M, Dragsted LO, Hermansen K. 2013. European journal of clinical nutrition. [Epub ahead of print]: x-x -
Effects of an isocaloric healthy Nordic diet on insulin sensitivity, lipid profile and inflammation markers in metabolic syndrome - a randomized study (SYSDIET)
Uusitupa M, Hermansen K, Savolainen MJ, Schwab U, Kolehmainen M, Brader L, Mortensen LS, Cloetens L, Johansson-Persson A, Önning G, Landin-Olsson M, Herzig K-H, Hukkanen J, Rosqvist F, Iggman D, Paananen J, Pulkki KJ, Siloaho M, Dragsted L, Barri T et.al.. 2013. Journal of internal medicine. 274: 52-66 -
Effects of rye and whole wheat versus refined cereal foods on metabolic risk factors: A randomised controlled two-centre intervention study
Giacco R, Lappi J, Costabile G, Kolehmainen M, Schwab U, Landberg R, Uusitupa M, Poutanen K, Pacini G, Rivellese AA, Riccardi G, Mykkänen H. 2013. Clinical nutrition. online: x-x -
Genetic predisposition to obesity and lifestyle factors - the combined analyses of twenty-six known BMI- and fourteen known waist:hip ratio (WHR)-associated variants in the Finnish Diabetes Prevention Study
Jääskeläinen T, Paananen J, Lindström J, Eriksson JG, Tuomilehto J, Uusitupa M. 2013. British journal of nutrition. 110: 1856-1965 -
Genetic risk score does not predict the outcome of obesity surgery
Käkelä P, Jääskeläinen T, Torpström J, Ilves I, Venesmaa S, Pääkkönen M, Gylling H, Paajanen H, Uusitupa M, Pihlajamäki J. 2013. Obesity surgery. online: - -
Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture
Berndt SI, Gustafsson S, Mägi R, Ganna A, Wheeler E, Feitosa MF, Justice AE, Monda KL, Croteau-Chonka DC, Day FR, Esko T, Fall T, Ferreira T, Gentilini D, Jackson AU, Luan J, Randall JC, Vedantam S, Willer CJ, Winkler TW, et al. (including Atalay M, Kuusisto J, Lakka TA, Stancakova A, Laakso M, Uusitupa M). 2013. Nature genetics. 45: 501-512 -
Glycerol and fatty acids in serum predict the development of hyperglycemia and type 2 diabetes in Finnish men
Mahendran Yuvaraj, Cederberg Henna, Vangipurapu Jagadish, Kangas Antti J, Soininen Pasi, Kuusisto Johanna, Uusitupa Matti, Ala-Korpela Mika, Laakso Markku. 2013. Diabetes care. 36: 3732-3738 -
History of medically treated diabetes and risk of Alzheimer disease in a nationwide case-control study
Tolppanen Anna-Maija, Lavikainen Piia, Solomon Alina, Kivipelto Miia, Uusitupa Matti, Soininen Hilkka, Hartikainen Sirpa. 2013. Diabetes care. 36: 2015-2019 -
Importance of weight loss maintenance and risk prediction in the prevention of type 2 diabetes: analysis of European Diabetes Prevention Study RCT
Penn L, White M, Lindström J, den Boer AT, Blaak E, Eriksson JG, Feskens E, Ilanne-Parikka P, Keinänen-Kiukaanniemi SM, Walker M, Mathers JC, Uusitupa M, Tuomilehto J. 2013. PLoS ONE. 8: e57143 -
Kohti terveellistä pohjoismaista ruokavaliota
Uusitupa M, Kolehmainen M, Schwab U, Poutanen K. 2013. Kehittyvä Elintarvike. 2: 48-50 -
Meta-analysis of gene-level associations for rare variants based on single-variant statistics
Hu Y-J, Berndt SI, Gustafsson S, Ganna A, Genetic Investigation of ANthropometric Traits (GIANT) Consortium (including M Atalay, T Lakka, J Kuusisto, M Laakso), Hirschhorn J, North KE, Ingelsson E, Lin D-Y et.al.. 2013. American journal of human genetics. 93: 236-248 -
Plasma alkylresorcinols reflect important whole-grain components of a healthy nordic diet
Magnusdottir OK, Landberg R, Gunnarsdottir I, Cloetens L, Åkersson B, Önning G, Jonsdottir SE, Rosqvist F, Schwab U, Herzig K-H, Savolainen MJ, Brader L, Hermansen K, Kolehmainen M, Poutanen K, Uusitupa M, Thorsdottir I, Risérus U. 2013. Journal of nutrition. 143: 1383-1390 -
Predictors of success of a lifestyle intervention in relation to weight loss and improvement in glucose tolerance among individuals at high risk for type 2 diabetes: the FIN-D2D project
Rautio N, Jokelainen J, Saaristo T, Oksa H, Keinänen-Kiukaanniemi S; for the FIN-D2D writing group. 2013. Journal of primary care and community health. 4: 59-66 -
Rasvainen kala muokkaa HDL-hiukkaskokoa ja lipidipitoisuuksia
Joukamo L, Lankinen M, Schwab U, Soininen P, Kangas AJ, Kolehmainen M, Paananen J, Poutanen K, Mykkänen H, Seppänen-Laakso T, Gylling H, Oresic M, Ala-Korpela M, Uusitupa M. 2013. Duodecim. 129: 2661-70 -
Serum Omega-3 Polyunsaturated Fatty Acids and Risk of Incident Type 2 Diabetes in Men: The Kuopio Ischaemic Heart Disease Risk Factor Study
Virtanen JK, Mursu J, Voutilainen S, Uusitupa M, Tuomainen T-P. 2013. Diabetes care. 37: 189-196 -
Sex-stratified Genome-wide Association Studies Including 270,000 Individuals Show Sexual Dimorphism in Genetic Loci for Anthropometric Traits
Randall JC, Winkler TW, Kutalik Z, Berndt SI, Jackson AU, Monda KL, Kilpeläinen TO, Esko T, Mägi R, Li S, Workalemahu T, Feitosa MF, Croteau-Chonka DC, Day FR, Fall T, Ferreira T, Gustafsson S, Locke AE, Mathieson I, Scherag A, et al. (including J Kuusisto, M Laakso, M Atalay, T Lakka). 2013. PLoS genetics. 9: e1003500 -
The Genetic and Metabolic Determinants of Cardiovascular Complications in Type 2 Diabetes: Recent Insights from Animal Models and Clinical Investigations
Avramoglu RK, Laplante M-A, Quang KL, Deshaies Y, Despres J-P, Larose E, Mathieu P, Poirier P, Perusse L, Vohl M-C, Sweeney G, Ylä-Herttuala S, Laakso M, Uusitupa M, Marette A. 2013. Canadian journal of diabetes. 37: 351-358 -
Trans-Ethnic Fine-Mapping of Lipid Loci Identifies Population-Specific Signals and Allelic Heterogeneity That Increases the Trait Variance Explained
Wu Y, Waite LL, Jackson AU, Sheu WH, Buyske S, Absher D, Arnett DK, Boerwinkle E, Bonnycastle LL, Carty CL, Cheng I, Cochran B, Croteau-Chonka DC, Dumitrescu L, Eaton CB, Franceschini N, Guo X, Henderson BE, Hindorff LA, Kim E, et al. (including Stancakova A, Kuusisto J, Laakso M, Uusitupa M, Rauramaa R Lakka T.). 2013. PLoS genetics. 9: e1003379 -
Weight reduction and increased physical activity to prevent the progression of obstructive sleep apnea: a 4-year observational postintervention follow-up of randomized clinical trial
Tuomilehto H, Seppä J, Uusitupa M, Tuomilehto J, Gylling H for the Kuopio Sleep Apnea Group. 2013. JAMA internal medicine. 173: 929-930 -
A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance
Manning AK, Hivert MF, Scott RA, Grimsby JL, Bouatia-Naji N, Chen H, Rybin D, Liu CT, Bielak LF, Prokopenko I, Amin N, Barnes D, Cadby G, Hottenga JJ, Ingelsson E, Jackson AU, Johnson T, Kanoni S, Ladenvall C, Lagou V et.al.. 2012. Nature genetics. 44: 659-669 -
Adiponectin receptor 1 gene (ADIPOR1) variant is associated with advanced age-related macular degeneration in Finnish population
Kaarniranta K, Paananen J, Nevalainen T, Sorri I, Seitsonen S, Immonen I, Salminen A, Pulkkinen L, Uusitupa M. 2012. Neuroscience letters. 513: 233-237 -
Association of the fat mass and obesity-associated (FTO) gene variant (rs9939609) with dietary intake in the Finnish Diabetes Prevention Study
Lappalainen Tiina, Lindström Jaana, Paananen Jussi, Eriksson Johan G, Karhunen Leila, Tuomilehto Jaakko, Uusitupa Matti for the Finnish Diabetes Prevention Study Group. 2012. British journal of nutrition. 108: 1859-65 -
Conjugated Bile Acids Associate with Altered Rates of Glucose and Lipid Oxidation after Roux-en-Y Gastric Bypass
Simonen M, Dali-Youcef N, Kaminska D, Venesmaa S, Käkelä P, Pääkkönen M, Hallikainen M, Kolehmainen M, Uusitupa M, Moilanen L, Laakso M, Gylling H, Patti ME, Auwerx J, Pihlajamäki J. 2012. Obesity surgery. 22: 1473-1480 -
Do statins interfere with lifestyle intervention in the prevention of diabetes in primary healthcare? One-year follow-up of the FIN-D2D project
Rautio N, Jokelainen J, Oksa H, Saaristo T, Peltonen M, Vanhala M, Puolijoki H, Moilanen L, Tuomilehto J, Keinänen-Kiukaanniemi S, Uusitupa M. 2012. BMJ open. 2: - -
Effects of n-6 PUFAs compared with SFAs on liver fat, lipoproteins, and inflammation in abdominal obesity: a randomized controlled trial
Bjermo H, Iggman D, Kullberg J, Dahlman I, Johansson L, Persson L, Berglund J, Pulkki K, Basu S, Uusitupa M, Rudling M, Arner P, Cederholm T, Ahlström H, Risérus U. 2012. American journal of clinical nutrition. 95: 1003-12 -
Family history of diabetes and effectiveness of lifestyle counselling on the cardio-metabolic risk profile in individuals at high risk of Type 2 diabetes: 1-year follow-up of the FIN-D2D project
Rautio N, Jokelainen J, Oksa H, Saaristo T, Peltonen M, Puolijoki H, Tuomilehto J, Vanhala M, Moilanen L, Uusitupa M, Keinänen-Kiukaanniemi S. 2012. Diabetic medicine. 29: 207-211 -
Gene expression of peripheral blood mononuclear cells as a tool in dietary intervention studies: What do we know so far?
de Mello VDF, Kolehmainen M, Schwab U, Pulkkinen L, Uusitupa M. 2012. Molecular nutrition and food research. 56: 1160-1172 -
How does lifestyle intervention affect depressive symptoms? Results from the Finnish Diabetes Prevention Study
Ruusunen A, Voutilainen S, Karhunen L, Lehto S. M., Tolmunen T, Keinänen-Kiukaanniemi S, Eriksson J, Tuomilehto J, Uusitupa M and Lindström J. 2012. Diabetic medicine. 29: e126-32 -
Improved lifestyle and decreased diabetes risk over 13 years: long-term follow-up of the randomised Finnish Diabetes Prevention Study (DPS)
Lindström J, Peltonen M, Eriksson JG, Ilanne-Parikka P, Aunola S, Keinänen-Kiukaanniemi S, Uusitupa M, Tuomilehto J. 2012. Diabetologia. online: - -
Insulin secretion and its determinants in the progression of impaired glucose tolerance to type 2 diabetes in impaired glucose-tolerant individuals: the finnish diabetes prevention study
de Mello Laaksonen VD, Lindström J, Eriksson J, Ilanne-Parikka P, Keinänen-Kiukaanniemi S, Sundvall J, Laakso M, Tuomilehto J, Uusitupa M. 2012. Diabetes care. 35: 211-217 -
Kehon koostumuksen arviointi
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Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways
Scott RA, Lagou V, Welch RP, Wheeler E, Montasser ME, Luan J, Mägi R, Strawbridge RJ, Rehnberg E, Gustafsson S, Kanoni S, Rasmussen-Torvik L, Yengo L, Lecoeur C, Shungin D, Sanna S, Sidore C, Johnson PCD, Jukema JW, Johnson T et.al.. 2012. Nature genetics. 44: 991-1005 -
Leukocyte Telomere Lenght in the Finnish Diabetes Prevention Study
Hovatta I, de Mello VDF, Kananen L, Lindström J, Eriksson JG, Ilanne-Parikka P, Keinänen-Kiukaanniemi S, Peltonen M, Tuomilehto J, Uusitupa M. 2012. PLoS ONE. 7: 1-6 -
Lihavuuden, tyypin 2 diabeteksen ja metabolisen oireyhtymän ehkäisy
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Long-term effects of placental growth on overweight and body composition
Eriksson JG, Gelow J, Thornburg KL, Osmond C, Laakso M, Uusitupa M, Lindi V, Kajatie E, Barker DJP. 2012. International journal of pediatrics. 2012: 6 pages -
Obesity and obstructive sleep apnea - Clinical significance of weight loss
Tuomilehto H, Seppä J, Uusitupa M. 2012. Sleep medicine reviews. online: - -
Participation, socioeconomic status and group of individual counselling intervention in individuals at high risk for type 2 diabetes: One-year follow-up study of the FIN-D2D-project
Rautio N, Jokelainen J, Oksa H, Saaristo T, Peltonen M, Niskanen L, Saltevo J, Korpi-Hyövälti E, Uusitupa M, Tuomilehto J, Keinänen-Kiukaanniemi S. 2012. Primary care diabetes. 6: 277-283 -
Ravinto, geenien toiminta, genomiikka ja epigenetiikka
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Uusitupa M, Schwab U. 2012. Erikoislääkäri. 22: 14-18 -
Ravintolisien lääkinnällinen käyttö
Uusitupa M, Schwab U. 2012. NIVELTIETO. 4: 18-21 -
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Ravitsemus, kihti ja reumataudit
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Ravitsemustilan arviointi
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Ruokavalio diabeteksen ehkäisyssä ja hoidossa
Uusitupa Matti. 2012. MEDIUUTISET. : 8-9 -
Sydämen vajaatoiminnan ravitsemushoito
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Ylipainon ja lihavuuden esiintyvyys tyypin 2 diabetespotilailla
Pajunen P, Keinänen-Kiukaanniemi S, Korpi-Hyövälti E, Männistö S, Niskanen L, Oksa H, Saaristo T, Saltevo J, Sundvall J, Vanhala M, Uusitupa M, Eriksson J, Peltonen M. 2012. Lääkärilehti. 67: 2621-2626 -
A diet high in fatty fish, bilberries and wholegrain products improves markers of endothelial function and inflammation in individuals with impaired glucose metabolism in a randomised controlled trial: The Sysdimet study
de Mello Vanessa D, Schwab Ursula, Kolehmainen Marjukka, Koenig W, Siloaho Maritta, Poutanen Kaisa, Mykkänen Hannu, Uusitupa Matti. 2011. Diabetologia. 54: 2755-2767 -
Ageing and associations of fasting plasma glucose and 2 h plasma glucose with HbA1g in apparently healthy population. " FIN-D2D" study
Saltevo JT, Kautiainen H, Niskanen L, Oksa H, Puolijoki H, Sundvall J, Keinänen-Kiukaanniemi S, Peltonen T, Tuomilehto J, Uusitupa M, Mäntyselkä P, Vanhala MJ. 2011. Diabetes research and clinical practice. 93: 344-349 -
Are we really active in the prevention of obesity and type 2 diabetes at the community level?
Uusitupa M, Tuomilehto J, Puska P. 2011. Nutrition metabolism and cardiovascular diseases. 21: 380-389 -
Association of ADIPOQ gene variants with body weight, type 2 diabetes and serum adiponectin concentrations: the Finnish Diabetes Prevention Study
Siitonen N, Pulkkinen L, Lindström J, Kolehmainen M, Eriksson JG, Venojärvi M, Ilanne-Parikka P, Keinänen-Kiukaanniemi S, Tuomilehto J & Uusitupa M. 2011. Bmc medical genetics. 12: 5 -
Association of ADIPOR2 gene variants with cardiovascular disease and type 2 diabetes risk in individuals with impaired glucose tolerance: the Finnish Diabetes Prevention Study
Siitonen N, Pulkkinen L, Lindstrom J, Kolehmainen M, Schwab U, Eriksson JG, Ilanne-Parikka P, Keinanen-Kiukaanniemi S, Tuomilehto J, Uusitupa M. 2011. Cardiovascular diabetology. 10: 83 -
Cardiovascular autonomic dysfunction is associated with central obesity in persons with impaired glucose tolerance
Laitinen T, Lindström J, Eriksson J, Ilanne-Parikka P, Aunola S, Keinänen-Kiukaanniemi S, Tuomilehto J, Uusitupa M. 2011. Diabetic medicine. 28: 699-704 -
Destiny in your own hands - Does a positive family history matter in the prevention of type 2 diabetes?
Uusitupa Matti, Tuomilehto Jaakko. 2011. Primary care diabetes. 5: 213-214 -
Family history of diabetes and effectiveness of lifestyle counselling on the cardiometabolic risk profile in individuals at high risk of type 2 diabetes: 1-year follow-up of the FIN-D2D project
Rautio N, Jokelainen J, Oksa H, Saaristo T, Peltonen M, Puolijoki H, Tuomilehto J,Vanhala M, Moilanen L, Uusitupa M, Keinänen-Kiukaanniemi S. 2011. . . -
HbA(1c) in diagnosing and predicting Type 2 diabetes in impaired glucose tolerance: the Finnish Diabetes Prevention Study
Pajunen P, Peltonen M, Eriksson JG, Ilanne-Parikka P, Aunola S, Keinänen-Kiukaanniemi S, Uusitupa M, Tuomilehto J & Lindström J: Finnish Diabetes Prevention Study. 2011. Diabetic medicine. 28: 36-42 -
Impact of positive family history and genetic risk variants on the incidence of diabetes - the Finnish Diabetes Prevention Study
Uusitupa MI, Stancáková A, Peltonen M, Eriksson JG, Lindström J, Aunola S, Ilanne-Parikka P, Keinänen-Kiukaanniemi S, Tuomilehto J, Laakso M. 2011. Diabetes care. Online: 1-6 -
Increase in physical activity and cardiometabolic risk profile change during lifestyle intervention in primary healthcare: 1-year follow-up study among individuals at high risk for type 2 diabetes
Kujala UM, Jokelainen J, Oksa H, Saaristo T, Rautio N, Moilanen L, Korpi-Hyövälti E, Saltevo J, Vanhala M, Niskanen L, Peltonen M, Tuomilehto J, Uusitupa M, Keinänen-Kiukaannemi S. 2011. BMJ open. 1: e000292 -
Long-term effect of betaine on risk factors associated with the metabolic syndrome in healthy subjects
Schwab U, Alfthan G, Aro A &Uusitupa M. 2011. European journal of clinical nutrition. 65: 70-76 -
Metabolically healthy and unhealthy obesity phenotypes in the general population: the FIN-D2D Survey
Pajunen P, Kotronen A, Korpi-Hyovalti E, Keinanen-Kiukaanniemi S, Oksa H, Niskanen L, Saaristo T, Saltevo JT, Sundvall J, Vanhala M, Uusitupa M, Peltonen M.. 2011. Bmc public health. 11: 754 -
Microfibrillar-associated protein 5 is linked with markers of obesity-related extracellular matrix remodeling and inflammation
Vaittinen M, Kolehmainen M, Schwab U, Uusitupa M, Pulkkinen L. 2011. Nutrition and diabetes. 1: e15, 1-6 -
Miksi kaikki eivät liho?
Uusitupa Matti, Lappalainen Tiina. 2011. Lääkärilehti. 66: 1811-1812a -
Millainen on sydämelle terveellinen ruokavalio?
Uusitupa Matti, Schwab Ursula. 2011. Duodecim. 127: 521-4 -
Mitä lihavuuden lääkehoidossa on luvassa?
Uusitupa Matti, Savolainen Markku. 2011. Lääkärilehti. 66: 2864-2866 -
Näkökulma. Karppaus - enemmän kuin muotivillitys?
Uusitupa Matti. 2011. Erikoislääkäri. : 144-145 -
Physical activity attenuates the influence of FTO variants on obesity risk: A meta-analysis of 218,166 adults and 19,268 children
Kilpeläinen Tuomas O, Qi Lu, Brage Soren, Sharp Stephen J., Sonestedt Emily, Demerath Ellen, Ahmad Tariq, Mora Samia, Kaakinen Marika, Sandholt Camilla H, Holzapfel Christina, Autenrieth Christine S., Hyppönen Elina, Cauchi Stéphane , He Meian, Kutalik Zoltan, Kumari Meena, Stancaková Alena, Meidtner Karina, Balkau Beverley et al.. 2011. PLoS medicine. 8: e1001116 -
Population-level effects of the national diabetes prevention programme (FIN-D2D) on the body weight, the waist circumference, and the prevalence of obesity.
Salopuro TM, Saaristo T, Oksa H, Puolijoki H, Vanhala M, Ebeling T, Niskanen L, Tuomilehto J, Uusitupa M, Peltonen M.. 2011. Bmc public health. 11: 350 -
Ravitsemussuosituksien nykylinjat YK:n agendalla
Uusitupa Matti. 2011. SYDÄN: SUOMEN SYDÄNTAUTILIITON JULKAISU. 54: 7 -
Response to Hoenselaar from Pedersen et al
Pedersen JI, Norum KR, James PT, Brouwer IA, Katan MB, Clarke R, Elmadfa I, Kris-Etherton PM, Kromhout D, Margetts BM, Mensink RP, Rayner M, Uusitupa M. 2011. British journal of nutrition. online: 452-454 -
Response to Ravnskov et al. on saturated fat and CHD
Pedersen JI, Norum KR, James PT, Brouwer IA, Katan MB, Clarke R, Elmadfa I, Kris-Etherton PM, Kromhout D, Margetts BM, Mensink RP, Rayner M, Uusitupa M.. 2011. British journal of nutrition. online: 458-460 -
Response to Slow et al.
Schwab U, Alfthan G, Aro A, Uusitupa M. 2011. European journal of clinical nutrition. 65: 772 -
Socioeconomic position and effectiveness of lifestyle intervention in prevention of type 2 diabetes: One-year follow-up of the FIN-D2D project
Rautio N, Jokelainen J, Oksa H, Saaristo T, Peltonen M, Niskanen L, Puolojoki H, Vanhala M, Uusitupa M, Keinänen-Kiukaanniemi S. & on the belalf of FIN-D2D study group. 2011. Scandinavian journal of public health. 39: 561-70 -
Solakaksi syömällä vai rajoittamalla hiilihydraatteja
Uusitupa Matti, Raussi Emmikaisa. 2011. Kehittyvä Elintarvike. 5: 12-15 -
Tenomodulin variants, APOE and Alzheimer's disease in a Finnish case-control cohort. Negative results
Tolppanen AM, Helisalmi S, Hiltunen M, Kolehmainen M, Schwab U, Pirttilä T, Pulkkinen L, Uusitupa M & Soininen H.. 2011. Neurobiology of aging. 32: 546.e7-546.e9 -
Tepsiikö vähähiilihydraattinen ruokavalio lihavuuden hoidossa?
Raussi Emmikaisa, Uusitupa Matti. 2011. Lääkärilehti. 66: 2659-2664a -
The importance of reducing SFA to limit CHD
Pedersen JI, James PT, Brouwer IA, Clarke R, Elmadfa I, Katan MB, Kris-Etherton PM, Kromhout D, Margetts BM, Mensink RP, Norum KR, Rayner M, Uusitupa M. 2011. British journal of nutrition. 106: 961-963 -
Whole grain products, fish and bilberries alter glucose and lipid metabolism in a randomized, controlled trial: the sysdimet study
Lankinen Maria, Schwab Ursula, Kolehmainen Marjukka, Paananen Jussi, Poutanen Kaisa, Mykkänen Hannu, Seppänen-Laakso Tuulikki, Gylling Helena, Uusitupa Matti, Ore¿ič Matej. 2011. PLoS ONE. 6: e22646 -
A psyllium fiber-enriched meal strongly attenuates postprandial gastrointestinal peptide release in healthy young adults
Karhunen LJ, Juvonen KR, Flander SM, Liukkonen K-H, Lähteenmäki L, Siloaho M, Laaksonen DE, Hetzig K-H, Uusitupa MI & Poutanen KS. 2010. Journal of nutrition. 140: 737-744 -
Association of the FTO gene variant (rs9939609) with cardiovascular disease in men with abnormal glucose metabolism - The Finnish Diabetes Prevention Study
Lappalainen T, Kolehmainen M, Schwab US, Tolppanen AM, Stančáková A, Lindström J, Eriksson JG, Keinänen-Kiukaanniemi S, Aunola S, Ilanne-Parikka P, Herder C, Koenig W, Gylling H, Kolb H &Tuomilehto J for the Finnish diabetes prevention study group. 2010. Nutrition metabolism and cardiovascular diseases. 2011/21: 691-698/2011 -
Best of sleep medicine 2010. Lifestyle intervention with weight reduction: first-line treatment in mild obstructive sleep apnea.
Ed. Lee-Chiong T. Contributors: Tuomilehto HPI, Seppä JM, Partinen MM, Peltonen M, Gylling H, Tuomilehto JO, Vanninen EJ, Kokkarinen J, Sahlman JK, et.al.. 2010. . . Teofilio Lee-Chiong -
Brain electrical activity during food presentation in obese binge-eating women
Tammela LI , Pääkkönen A, Karhunen LJ, Karhu J, Uusitupa MIJ & Kuikka JT. 2010. Clinical physiology and functional imaging. 30: 135-140 -
Cardiometabolic profile of people screened for high risk of type 2 diabetes in a national diabetes prevention programme (FIN-D2D)
Saaristo T, Moilanen L, Jokelainen J, Korpi-Hyövälti E, Vanhala M, Saltevo J, Niskanen L, Peltonen M, Oksa H, Cederberg H, Tuomilehto J, Uusitupa M, Keinänen-Kiukaanniemi S. 2010. Primary care diabetes. 4: 231-239 -
Cholesterol absorption decreases after Roux-en-Y gastric bypass but not after gastric banding
Pihlajamäki J, Grönlund S, Simonen M, Käkelä P, Moilanen L, Pääkkönen M, Pirinen E, Kolehmainen M, Kärjä V, Kainulainen S, Uusitupa M, Alhava E, Miettinen TA, Gylling H. 2010. Metabolism: clinical and experimental. 59: 866-872 -
Diabetesriskia voidaan vähentää perusterveydenhuollon keinoin. Taudin ilmaantuvuus pieneni D2D-hankkeessa
Saaristo T, Moilanen L, Jokelainen J, Oksa H, Korpi-Hyövälti E, Saltevo J, Vanhala M, Niskanen L, Peltonen M, Tuomilehto J, Uusitupa M & Keinänen-Kiukaanniemi S. 2010. Lääkärilehti. 65: 2369-2379 -
Diabetesriskiä voidaan vähentää perusterveydenhuollon keinoin. Taudin ilmaantuvuus pieneni D2D-hankkeessa.
Saaristo T, Moilanen L, Jokelainen J, Oksa H, Korpi-Hyövälti E, Saltevo J, Vanhala M, Niskanen L, Peltonen M, Tuomilehto J, Uusitupa M, Keinänen-Kiukaanniemi S. 2010. Lääkärilehti. 65: 2369-2379 -
Effect of weight loss on inflammation in patients with mild obstructive sleep apnea.
Sahlman J, Seppä J, Herder C, Peltonen M, Peuhkurinen K, Gylling H, Vanninen E, Tukiainen H, Punnonen K, Partinen M, Uusitupa M, Tuomilehto H.. 2010. Nutrition metabolism and cardiovascular diseases. online: 1-8 -
Gene Expression of FTO in Human Subcutaneous Adipose Tissue, Peripheral Blood Mononuclear Cells and Adipocyte Cell Line.
Lappalainen T, Kolehmainen M, Schwab U, Pulkkinen L, de Mello VD, Vaittinen M, Laaksonen DE, Poutanen K, Uusitupa M, Gylling H. 2010. Journal of nutrigenetics and nutrigenomics. 3: 37-45 -
Ghrelin in diabetes and metabolic syndrome
Pulkkinen L, Ukkola O, Kolehmainen M, Uusitupa M. 2010. International journal of peptides. 2010: ID 248948, 11 PAGES -
Leisure-time physical activity and the metabolic syndrome in the Finnish diabetes prevention study
Ilanne-Parikka P, Laaksonen DE, Eriksson JG, Lakka TA, Lindström J, Peltonen M, Aunola S, Keinänen-Kiukaanniemi S, Uusitupa M & Tuomilehto J. On behalf of the Finnish diabetes prevention study group. 2010. Diabetes care. 33: 1610-1617 -
Lifestyle intervention for prevention of type 2 diabetes in primary health care
Saaristo T, Moilanen L, Korpi-Hyövälti E, Vanhala M, Saltevo J, Niskanen L, Jokelainen J, Peltonen M, Oksa H, Tuomilehto J, Uusitupa M, Keinänen-Kiukaanniemi S.. 2010. Diabetes care. 33: 2146-2151 -
Lihavuuden ja glukoosiaineenvaihdunnan häiriöiden esiintyvyydessä on selviä alueellisia eroja Suomessa
Salopuro T, Saaristo T, Korpi-Hyövälti E, Oksa H, Keinänen-Kiukaanniemi S, Saltevo J, Vanhala M, Niskanen L, Moltchanova E, Sundvall J, Tuomilehto J, Uusitupa M, Peltonen M. 2010. Lääkärilehti. 65: 2381-2388 -
Mid-infrared spectroscopy and multivariate curve resolution
Lundbom J, Kolehmainen M Pulkkinen L, Soininen P , Tiainen M, Schwab U, Uusitupa M & Tammi M. 2010. European journal of lipid science and technology. 112: 1308-1314 -
Prevention strategies for type 2 diabetes should be based on evidence-based medical nutrition data.
Uusitupa M, Lindström J, Tuomilehto J. 2010. Diabetologia. 53: 1809-1810 -
Quality of diet is important for the prevention of cardiovascular disease.
Uusitupa Matti. 2010. Journal of internal medicine. 269: 148-9 -
Semisolid meal enriched in oat bran decreases plasma glucose and insulin levels, but does not change gastrointestinal peptide responses or short-term appetite in healthy subjects
Juvonen K, Salmenkallio-Marttila M, Lyly M, Liukkonen KH, Lähteenmäki L, Laaksonen D, Uusitupa M, Herzig K, Poutanen K & Karhunen L. 2010. Nutrition metabolism and cardiovascular diseases. 21/2011: 2011/748-756 -
Socio-economic differences in dysglycemia and lifestyle-related risk factors in the Finnish middle-aged population.
Wikström K, Lindström J, Tuomilehto J, Saaristo TE, Korpi-Hyövälti E, Oksa H, Vanhala M, Niskanen L, Keinänen-Kiukaanniemi S, Uusitupa M, Peltonen M. 2010. European journal of public health. online: 1-7 -
Sustained improvement in mild obstructive sleep apnea after a diet- and physical activity-based lifestyle intervention: postinterventional follow-up.
Tuomilehto H, Gylling H, Peltonen M, Martikainen T, Sahlman J, Kokkarinen J, Randell J, Tukiainen H, Vanninen E, Partinen M, Tuomilehto J, Uusitupa M, Seppä J; for the Kuopio Sleep Apnea Group.. 2010. American journal of clinical nutrition. 92: 688-696 -
Tenomodulin gene and obesity-related phenolypes
Tolppanen A-M, Kolehmainen M, Pulkkinen L & Uusitupa M. 2010. Annals of medicine. 42: 265-275 -
The activation of the inflammatory cytokines in overweight patients with mild obstructive sleep apnoea.
Sahlman J, Miettinen K, Peuhkurinen K, Seppä J, Peltonen M, Herder C, Punnonen K, Vanninen E, Gylling H, Partinen M, Uusitupa M, Tuomilehto H; Kuopio Sleep Apnoea Group. 2010. Journal of sleep research. 19: 341-348 -
The rs1800629 polymorphism in the TNF gene interacts with physical activity on the changes in C-reactive protein levels in the Finnish diabetes prevention study
Kilpeläinen TO, Laaksonen DE, Lakka TA, Herder C, Koenig W, Lindström J, Eriksson JG, Uusitupa M, Kolb H, Laakso M, Tuomilehto J, for the Finnish Diabetes Prevention Study Group. 2010. Experimental and clinical endocrinology and diabetes. 118: 757-759 -
Tyypin 2 diabetes - vakava paikka
Tuomilehto J, Uusitupa M. 2010. Lääkärilehti. 65: 2345 -
Anti-inflammatory effect of lifestyle changes in the Finnish diabetes prevention study
Herder C, Peltonen M, Koenig W, Sütfels K, Lindström J, Martin S, Ilanne-Parikka P, Eriksson JG, Aunola S, Keinänen-Kiukaanniemi S, Valle TT, Uusitupa M, Kolb H, Tuomilehto J, for the Finnish Diabetes Prevention Study Group. 2009. Diabetologia. 52: 433-442 -
Association of sequence variations in the gene encoding insulin-like growth factor binding protein 5 with adiponectin
Kallio P, Tolppanen A-M, Kolehmainen M, Poutanen K, Lindström J, Tuomilehto J, Kuulasmaa T, Kuusisto J, Pulkkinen L, Uusitupa M, Kallio P, Tolppanen A-M, Kolehmainen M, Poutanen K, Pulkkinen L, Uusitupa M. 2009. International journal of obesity. 33: 80-88 -
Educational attainment and effectiveness of lifestyle intervention in the Finnish diabetes prevention study
Wikström K, Peltonen M, Eriksson JG, Aunola S, Ilanne-Parikka P, Keinänen-Kiukaanniemi S, Uusitupa M, Tuomilehto J, Lindström J. 2009. Diabetes research and clinical practice. 86: e1-e5 -
Fatty fish intake decreases lipids related to inflammation and insulin signaling-A lipidomics approach
Lankinen M, Schwab U, Erkkilä A, Seppänen-Laakso T, Hannila M-L, Mussalo H, Lehto S, Uusitupa M, Gylling H, Oresic M. 2009. PLoS ONE. 4: [1-9] -
From the Authors: Avoiding the supine posture during sleep for patients with mild obstructive sleep apnea
Tuomilehto H, Seppä J, Partinen M, Uusitupa M. 2009. American journal of respiratory and critical care medicine -
From the authors: Long-term weight loss and maintenance in morbidly obese individuals wih obstructive sleep apnea
Tuomilehto H, Seppä J, Gylling H, Uusitupa M. 2009. American journal of respiratory and critical care medicine -
Lifestyle intervention with weight reduction. First line treatment in mild obstructive sleep apnea
Tuomilehto HPI, Seppä JM, Partinen MM, Peltonen M, Gylling H, Tuomilehto JOI, Vanninen EJ, Kokkarinen J, Sahlman JK, Martikainen T, Soini EJO, Randell J, Tukiainen H, Uusitupa M, on behalf of the Kuopio Sleep Apnea Group. 2009. American journal of respiratory and critical care medicine. 179: 320-327 -
Link between plasma ceramides, inflammation and insulin resistance: association with serum IL-6 concentration in patients with coronary heart disease
De Mello VDF, Lankinen M, Schwab U, Kolehmainen M, Lehto S, Seppä-Laakso T, Oresic M, Pulkkinen L, Uusitupa M, Erkkilä AT, De Mello VDF, Lankinen M, Schwab U, Kolehmainen M, Pulkkinen L, Uusitupa M. 2009. Diabetologia. 52: 2612-2615 -
Obstruktiivinen uniapnea ja lihavuus
Tuomilehto H, Seppä J, Gylling H, Uusitupa M. 2009. Duodecim -
Single nucleotide polymorphisms of the tenomodulin gene (TNMD) in age-related macular degeneration
Tolppanen A-M, Nevalainen T, Kolehmainen M, Seitsonen S, Immonen I, Uusitupa M, Kaarniranta K, Pulkkinen L, Tolppanen A-M, Kolehmainen M, Uusitupa M, Pulkkinen L. 2009. Molecular vision. 15: 762-770 -
Sleep duration, lifestyle intervention, and incidence of type 2 diabetes in impaired glucose tolerance. The Finnish diabetes prevention study
Tuomilehto H, Peltonen M, Partinen M, Lavigne G, Eriksson JG, Herder C, Aunola S, Keinänen-Kiukaanniemi S, Ilanne-Parikka P, Uusitupa M, Tuomilehto J, Lindström J, on behalf of the Finnish diabetes prevention study group. 2009. Diabetes care. 32: 1965-1971 -
Ten-year morality and cardiovaskular morabidity in the Finnish diabetes prevention study - secondary analysis of the randomized trial
Uusitupa M, Peltonen M, Lindström J, Aunola S, Ilanne-Parikka P, Keinänen-Kiukaanniemi S, Valle TT, Eriksson JG, Tuomilehto J, for the Finnish Diabetes Prevention Study Group. 2009. PLoS ONE. 4: e5656 -
The effect of fatty or lean fish intake on inflammatory gene expression in peripheral blood mononuclear cells of patients with coronary heart disease
De Mello VDF, Erkkilä AT, Schwab US, Pulkkinen L, Kolehmainen M, Atalay M, Mussalo H, Lankinen M, Oresic M, Lehto S, Uusitupa M, De Mello VDF, Schwab US, Pulkkinen L, Kolehmainen M, Lankinen M, Uusitupa M. 2009. European journal of nutrition. 48: 447-455 -
The effect of glycaemic control on the quantitative characteristics of retinopathy lesions in patients with type 2 diabetes mellitus: 10-year follow-up study
Kalesnykiene V, Sorri I, Voutilainen R, Uusitupa M, Niskanen L, Uusitalo H, Uusitupa M. 2009. Graefes archive for clinical and experimental ophthalmology. 247: 335-341 -
Variation in the UCP2 and UCP3 genes associated with abdominal obesity and serum lipids: The Finnish diabetes prevention study
Salopuro T, Pulkkinen L, Lindström J, Kolehmainen M, Tolppanen A-M, Eriksson JG, Valle TT, Aunola S, Ilanne-Parikka P, Keinänen-Kiukaanniemi S, Tuomilehto J, Laakso M, Uusitupa M, Salopuro T, Pulkkinen L, Kolehmainen M, Tolppanen A-M, Uusitupa M. 2009. Bmc medical genetics. 10: [13 p.] -
Viscosity of oat bran-enriched beverages influences gastrointestinal hormonal responses in healthy humans1-3
Juvonen KR, Purhonen A-K, Salmenkallio-Marttila M, Lähteenmäki L, Laaksonen DE, Herzig K-H, Uusitupa MIJ, Poutanen KS, Karhunen LJ, Juvonen KR, Uusitupa MIJ, Poutanen KS. 2009. Journal of nutrition. 139: 461-466 -
Determinants for the effectiveness of lifestyle intervention in the Finnish diabetes prevention study
Lindström J, Peltonen M, Eriksson JG, Aunola S, Hämäläinen H, Ilanne-Parikka P, Keinänen-Kiukaanniemi S, Uusitupa M, Tuomilehto J, for the Finnish Diabetes Prevention Study (DPS) group. 2008. Diabetes care. 31: 857-862 -
Downregulation of genes involved in NFkappaB activation in peripheral blood mononuclear cells after weight loss is associated with the improvement of insulin sensitivity in individuals with the metabolic syndrome: the GENOBIN study
De Mello V, Kolehmainen M, Pulkkinen L, Schwab U, Mager U, Laaksonen DE, Niskanen L, Gylling H, Atalay M, Rauramaa R, Uusitupa M, De Mello V, Kolehmainen M, Pulkkinen L, Schwab U, Mager U, Gylling H, Uusitupa M. 2008. Diabetologia. 51: 2060-2067 -
Effect of lifestyle intervention on the occurrence of metabolic syndrome and its components in the Finnish diabetes prevention study
Ilanne-Parikka P, Eriksson JG, Lindström J , Peltonen M, Aunola S, Hämäläinen H, Keinänen-Kiukaanniemi S, Laakso M, Valle TT, Lahtela J, Uusitupa M, Tuomilehto J, on behalf of the Finnish Diabetes Prevention Study Group. 2008. Diabetes care. 31: 805-807 -
Effect of weight loss on cytokine messenger RNA expression in peripheral blood mononuclear cells of obese subjects with the metabolic syndrome
de Mello VDF, Kolehmainen M, Schwab U, Mager U, Laaksonen DE, Pulkkinen L, Niskanen L, Gylling H, Atalay M, Rauramaa R, Uusitupa M, Ferreira de Mello V, Kolehmainen M, Schwab U, Mager U, Pulkkinen L, Gylling H, Uusitupa M. 2008. Metabolism: clinical and experimental. 57: 192-199 -
Effects of fatty and lean fish intake on blood pressure in subjects with coronary heart disease using multiple medications
Erkkilä AT, Schwab US, De Mello VDF, Lappalainen T, Mussalo H, Lehto S, Kemi V, Lamberg-Allardt C, Uusitupa MIJ. 2008. European journal of nutrition. 47: 319-328 -
Expression of ghrelin gene in peripheral blood mononuclear cells and plasma ghrelin concentrations in patients with metabolic syndrome
Mager U, Kolehmainen M, de Mello VDF, Schwab U, Laaksonen DE, Rauramaa R, Gylling G, Atalay M, Pulkkinen L, Uusitupa M, Mager U, Kolehmainen M, Ferreira, Schwab U, Gylling H, Pulkkinen L, Uusitupa M. 2008. European journal of endocrinology. 158: 499-510 -
Genetics or lifestyle - How do we prevent diabetes?
Uusitupa M. Teoksessa: (toim.) , 2008. European Endocrinolgy. [Online]. s. 19-21. Touch Briefings -
Heterogeneity of breast cancer associations with five susceptibility loci by clinical and pathological characteristics
Garcia-Closas M, Hall P, Nevanlinna H ..., Mannermaa A, Uusitupa M, Eskelinen M, Tengström M, Kosma V-M, Kataja V, Chenevix-Trench G .... 2008. PLoS genetics. 4: [e1000054] -
Inflammation markers are modulated by responses to diets differing in postprandial insulin responses in individulas with the metabolic syndrome1-3
Kallio P, Kolehmainen M, Laaksonen DE, Pulkkinen L, Atalay M, Mykkänen H, Uusitupa M, Poutanen K, Niskanen L, Kallio P, Kolehmainen M, Pulkkinen L, Mykkänen H, Uusitupa M, Poutanen K. 2008. American journal of clinical nutrition. 87: 1497-503 -
Interaction of single nucleotide polymorphisms in ADRB2, ADRB3, TNF, IL6, IGF1R, LIPC, LEPR, and GHRL with physical activity on the risk of type 2 diabetes mellitus and changes in characteristics of the metabolic syndrome. The Finnish Diabetes Prevention Study
Kilpeläinen TO, Lakka TA, Laakosnen DE, Mager U, Salopuro T, Kubaszek A, Todorova B, Laukkanen O, Lindström J, Eriksson JG, Hämäläinen H, Aunola S, Ilanne-Parikka P, Keinänen-Kiukaanniemi S, Tuomilehto J, Laakso M, Uusitupa M. 2008. Metabolism: clinical and experimental. 57: 428-436 -
Lifestyle intervention, diabetes, and cardiovascular disease
Lindström J, Uusitupa M. 2008. The Lancet -
Long-term repeatability of measures of early insulin secretion derived from an intravenous glucose tolerance test and conversion from impaired glucose tolerance to diabetes
Laaksonen DE, Niskanen L, Mykkänen H, Juntunen KS, Schwab U, Kolehmainen M, Rauramaa R, Tuomilehto J, Uusitupa M, Kolehmainen M, Uusitupa M. 2008. Annals of medicine. 40: 303-311 -
NAD(P)H:quinone oxidoreductase 1 NQ01*2 genotype (P187S) is a strong prognostic and predictive factor in breast cancer
Fagerholm Rainer, Hofstetter Barbara, Tommiska Johanna, Aaltonen Kirsimari, Vrtel Radek, Syrjäkoski Kirsi, Kallioniemi Anne, Kilpivaara Outi, Mannermaa Arto, Kosma Veli-Matti, Uusitupa Matti, Eskelinen Matti, Kataja Vesa, Aittomäki Kristiina. 2008. Nature genetics. 40: 844-853 -
SNPs in PPARG associte with type 2 diabetes and intract with physival activity
Kilpeläinen TO, Lakka TA, Laaksonen DE, Lindström J, Eriksson JG, Valle TT, Hämäläinen H, Ilanne-Parikka P, Keinänen-Kiukaanniemi S, Lindi V, Tuomilehto J, Uusitupa M, Laakso M. 2008. Medicine and science in sports and exercise. 40: 25-33 -
Serum concentrations and expressions of serum amyloid A and leptin in adipose tissue are interrelated: the Genobin Study
Lappalainen T, Kolehmainen M, Schwab U, Pulkkinen L, Laaksonen DE, Rauramaa R, Uusitupa M, Gylling H. 2008. European journal of endocrinology. 158: 333-341 -
The G-250A polymorphism in the hepatic lipase gene promotor is associated with changes in hepatic lipase activity and LDL cholesterol:The KANWU study
Lindi V, Schwab U, Louheranta A, Vessby B, Hermansen K, Tapsell L, Riccardi G, Rivellese AA, Laakso M, Uusitupa MIJ, KANWU Study Group. 2008. Nutrition metabolism and cardiovascular diseases. 18: 88-95 -
The genetic variation in the tenomodulin gene is associated with serum total and LDL cholesterol in a body size-dependent manner
Tolppanen A-M, Pulkkinen L, Kuulasmaa T, Kolehmainen M, Schwab U, Lindström J, Tuomilehto J, Uusitupa M, Kuusisto J. 2008. International journal of obesity. 32: 1868-1872 -
The genetic variation of the tenomodulin gene (TNMD) is associated with serum levels of systemic immune mediators--the Finnish Diabetes Prevention Study
Tolppanen AM, Pulkkinen L, Herder C, Koenig W, Kolehmainen M, Lindström J, Tuomilehto J, Uusitupa M. 2008. Genetics in medicine. 10: 536-544 -
Triacylglycerol fatty acid composition in diet-induced weight loss in subjects with abnormal glucose metabolism - the GENOBIN study
Schwab U, Seppänen-Laakso T, Yetukuri L, Ågren J, Kolehmainen M, Laaksonen DE, Ruskeepää A-L, Gylling H, Uusitupa M, Oresic M, for the Genobin Study Group, Schwab U, Kolehmainen M, Gylling H, Uusitupa M. 2008. PLoS ONE. 3: e2630 -
Variations in the ghrelin receptor gene associate with obesity and glucose metabolism in individuals with impaired glucose tolerance
Mager U, Degenhardt T, Pulkkinen L, Kolehmainen M, Tolppanen A-M, Lindström J, Eriksson JG, Carlberg, Tuomilehto J, Uusitupa M, for the Finnish Diabetes Prevention Study Group. 2008. PLoS ONE. 3: e2941 -
Weight reduction modulates expression of genes involved in extracellular matrix and cell death: the GENOBIN study
Kolehmainen M, Salopuro T, Schwab US, Kekäläinen J, Kallio P, Laaksonen DE, Pulkkinen L, Lindi VI, Sivenius K, Mager U, Siitonen N, Niskanen L, Gylling H, Rauramaa R, Uusitupa M, Kolehmainen M, Salopuro T, Schwab US, Kallio P, Pulkkinen L, Lindi VI. 2008. International journal of obesity. 32: 292-303 -
CYP1A1 and CYP1B1 genetic polymorphisms, smoking and breast cancer risk in a Finnish caucasian population
Sillanpää P, Heikinheimo L, Kataja V, Eskelinen M, Kosma V-M, Uusitupa M, Vainio H, Metsola K, Hirvonen A. 2007. Breast cancer research and treatment. 104: 287-297 -
Costs of a self-selected, health-promoting diet among the participants of the Finnish Diabetes Prevention Study
Ottelin A-M, Lindström J, Peltonen M, Martikainen J, Uusitupa M, Gylling H, Poutanen K, Louheranta A, Mannelin M, Paturi M, Salminen V, Tuomilehto J, Ottelin A-M, Uusitupa M, Gylling H, Poutanen K. 2007. Diabetes care. 30: 1275-1277 -
Dietary carbohydrate modification induces alterations in gene expression in abdominal subcutaneous adipose tissue in persons weith the metabolic syndrome: the FUNGENUT study1-4
Kallio P, Kolehmainen M, Laaksonen DE, Kekäläinen J, Salopuro T, Sivenius K, Pulkkinen L, Mykkänen HM, Niskanen L, Uusitupa M, Poutanen KS, Kallio P, Kolehmainen M, Poutanen KS. 2007. American journal of clinical nutrition. 85: 1417-1427 -
Fish oil, insulin sensitivity, insulin secretion and glucose toleranse in healthy people: Is there any effect of fish oil supplementation in relation to the type of backround diet and habitual dietary intake of n-6 and n-3 fatty acids?
Giacco R, Cuomo V, Vessby B, Uusitupa M, Hermansen K, Meyer BJ, Riccardi G, Rivellese AA, KANWU study group. 2007. Nutrition metabolism and cardiovascular diseases. 17: 572-580 -
Hiilihydraattien laatu säätelee geenien ilmentymistä rasvakudoksessa
Kallio P, Kolehmainen M, Laaksonen DE, Kekäläinen J, Salopuro T, Sivenius K, Pulkkinen L, Mykkänen HM, Niskanen L, Uusitupa M, Poutanen KS, Kallio P, Kolehmainen M, Salopuro T, Pulkkinen L, Mykkänen HM, Uusitupa M, Poutanen KS. 2007. Duodecim. 123: 1143-1144 -
Increased physical activity is a cornerstone in the prevention of type 2 diabetes in high-risk individuals
Laaksonen DE, Lindström J, Tuomilehto J, Uusitupa M. 2007. Diabetologia -
Kansantaudit, ravitsemus ja perimä
Uusitupa M. 2007. BOLUS : RAVITSEMUSTERAPEUTTIEN YHDISTYKSEN LEHTI. : 12-14 -
Lifestyle intervention to prevent diabetes in men and women with impaired glucose tolerance is cost-effective
Lindgren P, Lindström J, Tuomilehto J, Uusitupa M, Peltonen M, Jönsson B, De Faire U, Hellénius M-L, The DPS Study Group. 2007. International journal of technology assessment in health care. 23: 177-183 -
Moderate increase in dietary sucrose does not influence fasting or postprandial serum lipids regardless of the presence of apolipoprotein E2 allele in healthy subjects
Erkkilä AT, Schwab US, Ågren JJ, Hallikainen M, Gylling H, Uusitupa MIJ, Schwab US, Uusitupa MIJ. 2007. European journal of clinical nutrition. 61: 1094-1101 -
No observed local immunological response at cell level after five years of oats in adult coeliac disease
Kemppainen T, Janatuinen E, Holm K, Kosma V-M, Heikkinen M, Mäki M, Laurila K, Uusitupa M, Julkunen R. 2007. Scandinavian journal of gastroenterology. 42: 54-59 -
Physical activity modifies the effect of SNPs in the SLC2A2 (GLUT2) and ABCC8 (SUR1) genes on the risk of developing type 2 diabetes
Kilpeläinen TO, Lakka TA, Laaksonen DE, Laukkanen O, Lindström J, Eriksson JG, Valle TT, Hämäläinen H, Aunola S, Ilanne-Parikka P, Keinänen-Kiukaanniemi S, Tuomilehto J, Uusitupa M, Laakso M, for the Finnish Diabetes Prevention Study Group, Laakso M. 2007. Physiological genomics. 31: 264-272 -
Physical activity, diet, and incident diabetes in relation to an ADRA2B polymorphism
Laaksonen D, Siitonen N, Lindström J, Eriksson JG, Reunanen P, Tuomilehto J, Uusitupa M, for Finnish Diabetes Prevention Study Group. 2007. Medicine and science in sports and exercise. 39: 227-232 -
Serum adipokines are associated with cholesterol metabolism in the metabolic syndrome
Hallikainen M, Kolehmainen M, Schwab U, Laaksonen DE, Niskanen L, Rauramaa R, Pihlajamäki J, Uusitupa M, Miettinen TA, Gylling H, Kolehmainen M. 2007. Clinica chimica acta. 383: 126-132 -
Tenomodulin is associated with obesity and diabetes risk: the Finnish diabetes prevention study
Tolppanen AM, Pulkkinen L, Kolehmainen M, Schwab U, Lindström J, Tuomilehto J, Uusitupa M. 2007. Obesity. 15: 1082 -
Tyypin 2 diabeteksen ehkäisy
Laakso M, Uusitupa M. 2007. Duodecim. 123: 1439-1447 -
Variants of transcription factor 7-like 2 (TCF7L2) gene predict conversion to type 2 diabetes in the Finnish Diabetes Prevention Study and are associated with impaired glucose regulation and impaired insulin secretion
Wang J, Kuusisto J, Vänttinen M, Kuulasmaa T, Lindström J, Tuomilehto J, Uusitupa M, Laakso M, Laakso M. 2007. Diabetologia. 50: 1192-1200 -
Association between ghrelin gene variations and blood pressure in subjects with impaired glucose tolerance
Mager U, Kolehmainen M, Lindström J, Eriksson JG, Valle TT, Hämäläinen H, Ilanne-Parikka P, Keinänen-Kiukaanniemi S, Tuomilehto JO, Pulkkinen L, Uusitupa MI, for the Finnish diabetes prevention study group, Mager U, Kolehmainen M, Pulkkinen L. 2006. American journal of hypertension. 19: 920-926 -
Association of sequence variations in the gene encoding adoponectin receptor 1 (ADIPOR1) with body size and insulin levels. The Finnish diabetes prevention study
Siitonen N, Pulkkinen L, Mager U, Lindström J, Eriksson JG, Valle TT, Hämäläinen H, Ilanne-Parikka P, Keinänen-Kiukaanniemi S, Tuomilehto J, Laakso M, Uusitupa M, for the Finnish diabetes prevention study group, Siitonen N, Pulkkinen L, Mager U. 2006. Diabetologia. 49: 1795-1805 -
Association of the Leu72Met polymorphism of the ghrelin gene with the risk of type 2 diabetes in subjects with impaired glucose tolerance in the Finnish diabetes prevention study
Mager U, Lindi V, Lindström J, Eriksson JG, Vallet TT, Hämäläinen H, Ilanne-Parikka P, Keinänen-Kiukaanniemi S, Tuomilehto J, Laakso M, Pulkkinen L, Uusitupa M, for the Finnish diabetes prevention study group, Mager U, Lindi V, Pulkkinen L. 2006. Diabetic medicine. 23: 685-689 -
Dietary (n-3) fatty acids reduce plasma F2-isoprostanes but not prostaglandin F2alfa in healthy humans
Nälsén C, Vessby B, Berglund L, Uusitupa M, Hermansen K, Riccardi G, Rivellese A, Storlien L, Erkkilä A, Ylä-Herttuala S, Tapsell L, Basu S. 2006. Journal of nutrition. 136: 1222-1228 -
Effects of dietary saturared, monounsaturated, and n-3 fatty acids on blood pressure in healthy subjects 1-3
Rasmussen BM, Vessby B, Uusitupa M, Berglund L, Pedersen E, Riccardi G, Rivellese AA, Tapsell L, Hermandsen K, for the KANWU Study Group. 2006. American journal of clinical nutrition. 83: 221-226 -
Effects of hempseed and flaxseed oils on the profile of serum lipids, serum total and lipoprotein lipid concentrations and haemostatic factors
Schwab US, Callaway JC, Erkkilä AT, Gynther J, Uusitupa MIJ, Järvinen T. 2006. European journal of nutrition. 45: 470-477 -
High-fibre, low-fat diet predicts long-term weight loss and decreased type 2 diabetes risk: the Finnish diabetes prevention study
Lindström J, Peltonen M, Eriksson JG, Louheranta A, Fogelholm M, Uusitupa M, Tuomilehto J. 2006. Diabetologia. 49: 912-920 -
Impact of sugar beet pectin and polydextrose on fasting and postprandial glycemia and fasting concentrations of serum total and lipoprotein lipids in middle-aged subjects with abnormal glucose metabolism
Schwab U, Louheranta A, Törrrönen A, Uusitupa M. 2006. European journal of clinical nutrition. 60: 1073-1080 -
Ketkä tarvitsevat vitamiinejä?
Uusitupa M. 2006. Lääkärilehti -
Lihavan potilaan tutkiminen ja hoitomuodon valinta
Mustajoki P, Rissanen A, Uusitupa M. Teoksessa: Mustajoki P. Fogelholm M, Rissanen A, Uusitupa M(toim.) , 2006. Lihavuus. Ongelma ja hoito. 3. uud. p.. s. 158-166. Duodecim -
Lihavuus ja terveys
Uusitupa M. Teoksessa: Mustajoki P. Fogelholm M, Rissanen A, Uusitupa M(toim.) , 2006. Lihavuus. Ongelma ja hoito. 3. uud. p.. s. 25-38. Duodecim -
Orally administered betaine has an acute and dose-dependent effect on serum betaine and plasma homocysteine concentrations in healthy humans
Schwab U, Törrönen A, Meririnne E, Saarinen M, Alfthan G, Aro A, Uusitupa M. 2006. Journal of nutrition. 136: 34-38 -
Perimä ja lihavuus
Uusitupa M. Teoksessa: Mustajoki P. Fogelholm M, Rissanen A, Uusitupa M(toim.) , 2006. Lihavuus. Ongelma ja hoito. 3. uud. p.. s. 86-99. Duodecim -
Rasvakudos - aineenvaihdunta ja merkitys lihavuudessa
Kolehmainen M, Uusitupa M. Teoksessa: Mustajoki P. Fogelholm M, Rissanen A, Uusitupa M(toim.) , 2006. Lihavuus. Ongelma ja hoito. 3. uud. p.. s. 62-70. Duodecim -
Refinement of the 22q12-q13 Breast Cancer-Associated Region:Evidence of TMPRSS6 as a Candidate in an Eastern Finnish Population
Hartikainen JM, Tuhkanen H, Kataja V, Eskelinen M, Uusitupa M, Kosma V-M, Mannermaa A. 2006. Clinical cancer research. 12: 1454-1462 -
Serum uric acid as a harbinder of metabolic outcome in subjects with impaired glucose tolerance
Niskanen L, Laaksonen DE, Lindström J, Eriksson JG, Keinänen-Kiukaanniemi S, Ilanne-Parikka P, Aunola S, Hämäläinen H, Tuomilehto J, Uusitupa M, for the Finnish Diabetes Prevention Study Group. 2006. Diabetes care -
Sustained reductione in the incidence of type 2 diabetes by lifestyle intervention: follow-up of the Finnish diabetes prevention study
Lindström J, Ilanne-Parikka P, Peltonen M, Aunola S, Erikssom JG, Hämäläinen H, Härkönen P, Keinänen-Kiukaanniemi S, Laakso M, Louheranta A, Mannelin M, Paturi M, Sundvall J, Valle TT, Uusitupa M, Tuomilehto J. 2006. The Lancet. 368: 1673-1679 -
Systemic immune mediators and lifestyle changes in the prevention of type 2 diabetes. Results from the Finnish diabes prevention study
Herder C, Peltonen M, Koenig W, Kräft I, Mûller-Scholze S, Martin S, Lakka T, Ilanne-Parikka P, Eriksson JG, Hämäläinen H, Keinänen-Kiukaanniemi S, Valle TT, Uusitupa M, Lindström J, Kolb H, Tuomilehto J. 2006. Diabetes. 55: 2340-2346 -
Tyypin 2 diabetes on ehkäistävissä ja niksit ovat tiedossa
Uusitupa M, Tuomilehto J. 2006. Duodecim -
An autosome-wide scan for linkage disequilibrium-based association in sporadic breast cancer cases in Eastern Finland: three candidate regions found
Hartikainen JM, Tuhkanen H, Kataja V, Dunning AM, Antoniou A, Smith P, Arffman A, Pirskanen M, Easton DF, Eskelinen M, Uusitupa M, Kosma V-M, Mannermaa A. 2005. Cancer epidemiology biomarkers and prevention. 14: 75-80 -
Antibodies against oxidized LDL and cardiolipin and mortality in patients with coronary heart disease
Erkkilä AT, Närvänen O, Lehto S, Uusitupa MIJ, Ylä-Herttuala S. 2005. Atherosclerosis. 183: 157-162 -
Antropometriset mittaukset
Uusitupa M, Fogelholm M. Teoksessa: Aro A, Mutanen M, Uusitupa M(toim.) , 2005. Ravitsemustiede. 2. uud. p.. s. 276-281. Duodecim -
Gene-diet interaction in relation to the prevention of obesity and type 2 diabetes: Evidence from the Finish diabetes prevention study
Uusitupa M, Uusitupa M. 2005. Nutrition metabolism and cardiovascular diseases. 15: 225-233 -
Genetic variation in leptin receptor gene is associated with type 2 diabetes and body weight: The Finnish diabetes prevention study
Salopuro T, Pulkkinen L, Lindström J, Eriksson JG, Valle TT, Hämäläinen H, Ilanne-Parikka P, Keinänen-Kiukaanniemi S, Tuomilehto J, Laakso M, Uusitupa M, for the Finnish Diabetes Prevention Study Group, Salopuro T, Pulkkinen L, Uusitupa M, Laakso M. 2005. International journal of obesity. 29: 1245-1251 -
Improved fibrinolysis by an intensive lifestyle intervention in subjects with impaired glucose tolerance. The Finnish diabetes prevention study
Hämäläinen H, Rönnemaa T, Virtanen A, Lindström J, Eriksson JG, Valle TT, Ilanne-Parikka P, Keinänen-Kiukaanniemi S, Rastas M, Aunola S, Uusitupa M, TuomilehtoJ, on behalf of the Finnish Diabetes Prevention Study Group. 2005. Diabetologia. 48: 2248-2253 -
Kehon koostumuksen arviointi
Fogelholm M, Uusitupa M. Teoksessa: Aro A, Mutanen M, Uusitupa M(toim.) , 2005. Ravitsemustiede. 2. uud. p.. s. 282-290. Duodecim -
Lihavuus
Uusitupa M. Teoksessa: Aro A, Mutanen M, Uusitupa M(toim.) , 2005. Ravitsemustiede. 2. uud. p.. s. 369-393. Duodecim -
Liikunta, energiankulutus ja ravitsemus
Uusitupa M. Teoksessa: Vuori I, Taimela S, Kujala U(toim.) , 2005. Liikuntalääketiede. 3. uud. p.. s. 60-75. Duodecim -
Muuttaako lihavuusepidemia kansanterveytemme kehityssuunnan
Uusitupa M. 2005. Elintarvike ja Terveys. : 22-24 -
NAT2 slow acetylator genotype as an important modifier of breast cancer risk
Sillanpää P, Hirvonen A, Kataja V, Eskelinen M, Kosma V-M, Uusitupa M, Vainio H, Mitrunen K. 2005. International journal of cancer. 114: 579-584 -
Nuorten nopea lihominen hätkähdyttää
Laitinen J, Uusitupa M. 2005. Lääkärilehti -
Nutrigenomiikka - avain ravintotekijöiden molekulaaristen vaikutusten selvittämiseen. Ravinnon ja perintötekijöiden yhteisvaikutusten salat julki
Kolehmainen M, Poutanen K, Uusitupa M, Poutanen K. 2005. Duodecim -
Physical activity in the prevention of type 2 diabetes. The Finnish diabetes prevention study
Laaksonen DE, Lindström J, Lakka TA, Eriksson JG, Niskanen L, Wikström K, Aunola S, Keinänen-Kiukaanniemi S, Laakso M, Valle TT, Ilanne-Parikka P, Louheranta A, Hakumäki M, Kaikkonen H, Härkönen P, Sundvall J, Tuomilehto J, Uusitupa M, Louheranta A. 2005. Diabetes. 54: 158-165 -
Polymorphisms in the SLC2A2 (GLUT2) gene are associated with the conversation from impaired glucose tolerance to type 2 diabetes.The Finnish diabetes prevention study
Laukkanen O, Lindström J, Eriksson J, Valle TT, Hämäläinen H, Ilanne-Parikka P, Keinänen-Kiukaanniemi S, Tuomilehto J, Uusitupa M, Laakso M, Laakso M. 2005. Diabetes. 54: 2256-2260 -
Ravitsemus ja diabetes
Uusitupa M. Teoksessa: Aro A, Mutanen M, Uusitupa M(toim.) , 2005. Ravitsemustiede. 2. uud. p.. s. 394-424. Duodecim -
Ravitsemustilan arviointi
Uusitupa M, Fogelholm M. Teoksessa: Aro A, Mutanen M, Uusitupa M(toim.) , 2005. Ravitsemustiede. 2. uud. p.. s. 291-296. Duodecim -
Sokeri ja diabetes - onko syytä kiristää suitsia?
Uusitupa M, Uusitupa M. 2005. Lääkärilehti. 60: 1557-1558 -
Subtle hyperproinsulinaemia characterises the defective insulin secretory capacity in offspring of glutamic acid decarboxylase antibody-positive patients with latent autoimmune diabetes mellitus in adults
Vauhkonen I, Niskanen L, Knip M, Moilanen Mykkänen L, Uusitupa M, Laakso M. 2005. European journal of endocrinology. 153: 265-273 -
Sulfotransferase 1A1 genotype as a potential modifier of breast cancer risk among premenopausal women
Sillanpää P, Kataja V, Eskelinen M, Kosma V-M, Uusitupa M, Vainio H, Mitrunen K, Hirvonen A. 2005. Pharmacogenetics and genomics. 15: 749-752 -
XRCC1 and XPD genetic polymorphisms, smoking and breast cancer risk in the Finnish case-control study
Metsola K, Kataja V, Sillanpää P, Siivola P, Heikinheimo L, Eskelinen M, Kosma V-M, Uusitupa M, Hirvonen A. 2005. Breast cancer research. 7: R987-R997 -
Aldose reductase gene polymorphisms and peripheral nerve function in patients with type 2 diabetes
Sivenius K, Pihlajamäki J, Partanen J, Niskanen L, Laakso M, Uusitupa M. 2004. Diabetes care. 27: 2021-2026 -
Aldose reductase gene polymorphisms and susceptibility to microvascular complications in type 2 diabetes
Sivenius K, Niskanen L, Voutilainen-Kaunisto R, Laakso M, Uusitupa M. 2004. Diabetic medicine. 21: 1325-1333 -
Association between a deletion/insertion polymorphism in the alfa2B-adrenergic receptor gene and insulin secretion and type 2 diabetes. The Finnish diabetes prevention study
Siitonen N, Lindström J, Eriksson J, Valle TT, Hämäläinen H, Ilanne-Parikka P, Keinänen-Kiukaanniemi S, Tuomilehto J, Laakso M, Uusitupa M. 2004. Diabetologia. 47: 1416-1424 -
Common polymorphisms in the genes regulating the early insulin signalling pathway: effects on weight change and the conversion from impaired glucose tolerance to Type 2 diabetes
Laukkanen O, Pihlajamäki J, Lindström J, Eriksson J, Valle TT, Hämaläinen H, Ilanne-Parikka P, Keinänen-Kiukaanniemi S, Tuomilehto J, Uusitupa M, Laakso M, for the Finnish Diabetes Prevention Study Group, Laakso M. 2004. Diabetologia. 47: 871-877 -
Common variants in beta2- and beta3-adrenergic receptor genes and uncoupling protein 1 as predictors of the risk for type 2 diabetes and body weight changes. The Finnish diabetes prevention study
Salopuro T, Lindström J, Eriksson JG, Hämäläinen H, Ilanne-Parikka P, Keinänen-Kiukaanniemi S, Tuomilehto J, Laakso M, Uusitupa M, Finnish Diabetes Preventio Study Group. 2004. Clinical genetics -
Comparative evaluation of simple indices of insulin resistance
Vaccaro O, Masulli M, Vincenzo C, Rivellese AA, Uusitupa M, Vessby B, Hermansen K, Tapsell L, Riccardi G. 2004. Metabolism: clinical and experimental. 53: 1522-1526 -
Dyslipidemiat
Suomen Sisätautilääkärien Yhdistys ry:n asettama työryhmä, Gylling H, Uusitupa M, Laakso M. 2004. Duodecim. 120: 1794-1816 -
Elämäntapamuutokset korjaavat pysyvästi insuliiniresistenssia heikentyneessä sokerinsiedossa
Uusitupa M, Lindi V, Louheranta A, Salopuro T, Lindström J, Tuomilehto J, Salopuro T. 2004. Duodecim. 120: 1495-1497 -
Epidemiology and treatment of the metabolic syndrome
Laaksonen DE, Niskanen L, Lakka H-M, Lakka TA, Uusitupa M, Laaksonen DE. 2004. Annals of medicine. 36: 332-346 -
Evidence-based nutritional approaches to treatment and prevention of diabetes mellitus
Mann JI, De Leeuw I, Hermansen K, Karamanos B, Karlström B, Katsilamros N, Riccardi G, Rivellese AA, Rizkalla S, Slama G, Toeller M, Uusitupa M, Vessby B, on behalf of the (DNSG) of the (EASD). 2004. Nutrition metabolism and cardiovascular diseases. 14: 373-394 -
Interactions between peroxisome proliferator-activated receptor-gamma 2 gene polymorphisms and size at birth on blood pressure and the use of antihypertensive medication
Yliharsila H, Eriksson JG, Forsen T, Laakso M, Uusitupa M, Osmond C, Barker DJ, Laakso M. 2004. Journal of hypertension. 22: 1283-1287 -
Leucine7 to proline7 polymorphism in prepro-NPY gene and femoral neck bone mineral density in postmenopausal women
Heikkinen A-M, Niskanen LK, Salmi JA, Koulu M, Pesonen U, Uusitupa MIJ, Komulainen MH, Tuppurainen MT, Kröger H, Jurvelin J, Saarikoski S, Kröger H. 2004. Bone. 35: 589-594 -
Long-term results, late complications and quality of life in a series of adjustable gastric banding
Martikainen T, Pirinen E, Alhava E, Poikolainen E, Pääkkönen M, Uusitupa M, Gylling H. 2004. Obesity surgery. 14: 648-654 -
Perinnöllisen kombinoituneen hyperlipidemian (FKH) geneettinen tausta - rengas kiristyy
Uusitupa M. 2004. Duodecim -
Polymorphisms of the SUR1 (ABCC8) and Kir6.2 (KCNJ11) genes predict the conversion from impaired glucose tolerance to type 2 diabetes. The Finnish diabetes prevention study
Laukkanen O, Pihlajamäki J, Lindström J, Eriksson J, Valle TT, Hämäläinen H, Ilanne-Parikka P, Keinänen-Kiukaanniemi S, Tuomilehto J, Uusitupa M, Laakso M, for the Finnish diabetes prevention study group. 2004. Journal of clinical endocrinology and metabolism. 89: 6286-6290 -
Prevalence of the metabolic syndrome and its components. Finding from a Finnish general population sample and the diabetes prevention study cohort
Ilanne-Parikka P, Eriksson JG, Lindström J, Hämäläinen H, Keinänen-Kiukaanniemi S, Laakso M, Louheranta A, Mannelin M, Rastas M, Salminen V, Aunola S, Sundvall J, Valle T, Lahtela J, Uusitupa M, Tuomilehto J. 2004. Diabetes care. 27: 2135-2140 -
Ravitsemus- ja liikuntasuositukset linjaavat tervytemme perustan
Uusitupa M. 2004. Lääkärilehti -
The G-250A promoter polymorphism of the hepatic lipase gene predicts the conversion from impaired glucose tolerance to type 2 diabetes mellitus: the Finnish Diabetes Prevention Study
Todorova B, Kubaszek A, Pihlajamäki J, Lindström J, Eriksson J, Valle TT, Hämäläinen H, Ilanne-Parikka P, Keinänen-Kiukaanniemi S, Tuomilehto J, Uusitupa M, Laakso M, Laakso M. 2004. Journal of clinical endocrinology and metabolism. 89: 2019-2023 -
The effect of meat products enriched with plant sterols and minerals on serum lipids and blood pressure
Tapola NS, Lyyra ML, Karvonen HM, Uusitupa MI, Sarkkinen ES. 2004. International journal of food sciences and nutrition. 55: 389-397 -
Vitamin D receptor gene polymorphism as an important modifier of positive family history related breast cancer risk
Sillanpää P, Hirvonen A, Kataja V, Eskelinen M, Kosma V-M, Uusitupa M, Vainio H, Mitrunen K. 2004. Pharmacogenetics and genomics. 14: 239-245 -
A deletion in the alfa2B-adrenergic receptor gene and autonomic nervous function in central obesity
Sivenius K, Niskanen L, Laakso M, Uusitupa M, Laakso M. 2003. Obesity. 11: 962-970 -
Aineenvaihdunnan ja ravitsemuksen häiriöt
Uusitupa M. Teoksessa: Koskenvuo K(toim.) , 2003. Sairauksien ehkäisy. 2. uud. p.. s. 208-215. Duodecim -
Aivojen kuvantaminen syömishäiriöiden ja lihavuuden tutkimuksessa
Karhunen L, Kuikka JT, Uusitupa M. 2003. Duodecim. 119: 859-865 -
Association of the PRO12ALA polymorphism of the PPAR-gamma2 gene with oxidized low-density lipoprotein and cardiolipin autoantibodies in nondiabetic and type 2 diabetic subjects
Niskanen L, Lindi V, Erkkilä A, Sivenius K, Luoma J, Ylä-Herttuala S, Laakso M, Uusitupa MIJ, Laakso M. 2003. Metabolism: clinical and experimental. 52: 213-217 -
Diabetes
Uusitupa M. Teoksessa: Koskenvuo K(toim.) , 2003. Sairauksien ehkäisy. 2. uud. p.. s. 216-225. Duodecim -
Effect of the pro12ala polymorphism in the peroxisome proliferator-activated receptor (PPAR) gamma2 gene on the expression of PPARgamma target genes in adipose tissue of massively obese subjects
Kolehmainen M, Uusitupa MIJ, Alhava E, Laakso M, Vidal H, Laakso M. 2003. Journal of clinical endocrinology and metabolism. 88: 1717-1722 -
Effects of dietary saturated, monounsaturated and n-3 fatty acids on fasting lipoproteins, LDL size and post-prandial lipid metabolism in healthy subjects
Rivellese AA, Maffettone A, Vessby B, Uusitupa M, Hermansen K, Berglund L, Louheranta A, Meyer BJ, Riccardi G. 2003. Atherosclerosis. 167: 149-158 -
Efficacy and safety of plant stanols and sterols in the management of blood cholesterol levels
Katan MB, Grundy SM, Jones P, Law M, Miettinen T, Paoletti R, for the Stresa Workshop participants, Gylling H, Uusitupa M. 2003. Mayo Clinic Proceedings. 78: 965-978 -
Impact of the pro12ala polymorphism of the PPAR-gamma2 gene on serum triacylglycerol response to n - 3 fatty acid supplementation. For the KANWU study group
Lindi V, Schwab U, Louheranta A, Laakso M, Vessby B, Hermansen K, Storlien L, Riccardi G, Rivellese AA, Uusitupa MIJ, for the KANWU Study Group, Laakso M. 2003. Molecular genetics and metabolism. 79: 52-60 -
Interactions between peroxisome proliferator-activated receptor gene polymorphism and birth length influence risk for type 2 diabetes
Eriksson JG, Osmond C, Lindi V, Uusitupa M, Forsen T, Laakso M, Barker D, Laakso M. 2003. Diabetes care -
Intressiristiriidat lääketieteelisen tutkimuksen rahoituksessa.Yhteisillä pelisäännöillä ongelmat vähenevät
Uusitupa M. 2003. Duodecim -
Long-term improvement in insulin sensitivity by changing lifestyles of people with impaired glucose tolerance.4-year results from the Finnish diabetes prevention study
Uusitupa M, Lindi V, Louheranta A, Salopuro T, Lindström J, Tuomilehto J, for the Finnish Diabetes Prevention Study Group. 2003. Diabetes. 52: 2532-2538 -
Prevention of diabetes mellitus in subjects with impaired glucpse tolerance in the Finnish diabetes prevention study: Results from a randomized clinical trial
Lindström J, Eriksson JG, Valle TT, Aunola S, Cepaitis Z, Hakumäki M, Hämäläinen H, Ilanne-Parikka P, Keinänen-Kiukaanniemi S, Laakso M, Louheranta A, Mannelin M, Martikkala V, Moltchanov V, Rastas M, Salminen V, Sundvall J, Uusitupa M, Tuomilehto J. 2003. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY. SUPPLEMENT. 14: S108-S113 -
Prolonged corrected QT interval is associated with acute and chronic hyperinsulinemia in nondiabetic subjects
Laitinen T, Vauhkonen I, Niskanen L, Hartikainen J, Uusitupa M, Laakso M. 2003. Diabetes care -
Promoter polymorphisms of the TNF-alfa (G-308A) and IL-6 (C-174G) genes predict the conversion from impaired glucose tolerance to type 2 diabetes. The Finnish Diabetes Prevention Study
Kubaszek A, Pihlajamäki J, Komarovski V, Lindi V, Lindström J, Eriksson J, Valle TT, Hämäläinen H, Ilanne-Parikka P, Keinänen-Kiukaanniemi S, Tuomilehto J, Uusitupa M, Laakso M, Laakso M. 2003. Diabetes. 52: 1872-1876 -
The Finnish Diabetes Prevention Study (DPS): Lifestyle intervention and 3-year results on diet and physical activity
Lindström J, Louheranta A, Mannelin M, Rastas M, Salminen V, Eriksson J, Uusitupa M, Tuomilehto J, for the Finnish Diabetes Prevention Study Group. 2003. Diabetes care. 26: 3230-3236 -
The Leu7Pro polymorphism of the neuropeptide Y gene regulates free fatty acid metabolism
Pihlajamäki J, Karhapää P, Vauhkonen I, Kekäläinen P, Kareinen A, Viitanen L, Pesonen U, Kallio J, Uusitupa M, Laakso M. 2003. Metabolism: clinical and experimental. 52: 643-646 -
The effect of intensified diet conseling on the diet of hypertensive subjects in primary health care: a 2-year open randomized controlled trial of lifestyle intervention against hypertension in eastern Finland
Korhonen M, Kastarinen M, Uusitupa M, Puska P, Nissinen A. 2003. Preventive medicine. 36: 8-16 -
The effects of the Pro12Ala polymorphism of the PPARgamma-2 gene on lipid metabolism interact with body size at birth
Eriksson J, Lindi V, Uusitupa M, Forsén T, Laakso M, Osmond C, Barker D, Laakso M. 2003. Clinical genetics. 64: 366-370 -
Tolerance of symptomatic lactose malabsobers to lactose in milk chocolate
Järvinen RMK, Loukaskorpi M, Uusitupa MIJ. 2003. European journal of clinical nutrition. 57: 701-705 -
Treatment improves serotonin transporter binding and reduces binge eating
Tammela LI, Rissanen A, Kuikka JT, Karhunen LJ, Bergström KA, Repo-Tiihonen E, Naukkarinen H, Vanninen E, Tiihonen J, Uusitupa M. 2003. Psychopharmacology. 170: 89-93 -
Uudistuuko psykiatria terveydenhuollossa
Uusitupa M. Teoksessa: Valkonen-Korhonen M, Lehtonen K, Tuovinen T(toim.) , 2003. Mielenterveys uusiutuvana voimavarana. s. 272-276. Helsinki University Press -
n-3 fatty acids and 5-y risks of death and cardiovascular disease events in patients with coronary artery disease1-3
Erkkilä AT, Lehto S, Pyörälä K, Uusitupa MIJ. 2003. American journal of clinical nutrition. 78: 65-71 -
A meta-analytic investigation of linkage and association of common leptin receptor (LEPR) polymorphisms with body mass index an waist circumference
Heo M, Leibel RL, Fontaine KR, Boyer BB, Chung WK, Koulu M, Karvonen MK, Pesonen U, Rissanen A, Laakso M, Uusitupa MIJ, Chagnon Y, Bouchard C, Donohoue PA, Burns TL, Shuldiner AR, Silver K, Andersen RE, Pedersen O, Echwald S, Sorensen TIA, Behn P, Permutt MA, Jacobs KB, Elston RC, Hoffman DJ, Gropp E, Allison DB. 2002. International journal of obesity. 26: 640-646 -
Anthropometry, bioelectrical impedance and dual-energy X-ray absorptiometry in the assessment of body composition in elderly Finnish women
Haapala I, Hirvonen A, Niskanen L, Uusitupa M, Kröger H, Alhava E, Nissinen A. 2002. Clinical physiology and functional imaging. 22: 383-391 -
Association of leucine 7 to proline 7 polymorphism in the preproneuropeptide Y with serum lipids in patients with coronary heart disease
Erkkilä AT, Lindi V, Lehto S, Laakso M, Uusitupa MIJ. 2002. Molecular genetics and metabolism. 75: 260-264 -
Association of the Pro12Ala polymorphism in the PPAR-gamma2 with 3-year incidence of type 2 diabetes and body weight change in the Finnish Diabetes Prevention Study
Lindi VI, Uusitupa MIJ, Lindström J, Louheranta A, Eriksson JG, Valle TT, Hämäläinen H, Ilanne-Parikka P, Keinänen-Kiukaanniemi S, Laakso M, Tuomilehto J, for the Finnish Diabetes Prevention Study Group. 2002. Diabetes. 51: 2581-2586 -
Association of the fatty acid profile of serum lipids with glucose and insulin metabolism during 2 fat-modified diets in subjects with impaired glucose tolerance 1-3
Louheranta AM, Sarkkinen ES, Vidgren HM, Schwab US, Uusitupa MIJ. 2002. American journal of clinical nutrition. 76: 331-337 -
Betaine supplementation decreases plasma homocysteine concentrations but does not affect body weight, body composition, or resting energy expenditure in human subjets 1,2,3
Schwab U, Törrönen A, Toppinen L, Alftan G, Saarinen M, Aro A, Uusitupa M. 2002. American journal of clinical nutrition. 76: 961-967 -
Combined COMT and GST genotypes and hormone replacement therapy associated breast cancer risk
Mitrunen K, Kataja V, Eskelinen M, Kosma V-M, Kang D, Benhamou S, Vainio H, Uusitupa M, Hirvonen A. 2002. Pharmacogenetics and genomics. 12: 67-72 -
Effect of alfa-linolenic acid-rich camelina sativa oil on serum fatty acid composition and serum lipids in hypercholesterolemic subjects
Karvonen HM, Aro A, Tapola NS, Salminen I, Uusitupa MIJ, Sarkkinen ES. 2002. Metabolism: clinical and experimental. 51: 1253-1260 -
Elämäntapamuutokset tehokkaita tyypin 2 diabeteksen ehkäisyssä. Diabetes prevention study, DPS
Valle TT, Lindström J, Eriksson JG, Hämäläinen H, Parikka P-I, Keinänen-Kiukaanniemi S, Louheranta A, Laakso M, Martikkala V, Rastas M, Salminen V, Aunola S, Hakumäki M, Mannelin M, Sundvall J, Uusitupa M, Tuomilehto J. 2002. Lääkärilehti. 57: 1369-1377 -
Hormone sensitive lipase expression and adipose tissue metabolism show gender difference in obese subjects after weight loss
Kolehmainen M, Vidal H, Ohisalo JJ, Pirinen E, Alhava E, Uusitupa MIJ. 2002. International journal of obesity. 26: 6-16 -
Iris transluminance in type 2 diabetes
Voutilainen-Kaunisto R, Niskanen L, Uusitupa M, Teräsvirta M. 2002. Acta ophthalmologica. 80: 64-68 -
Lifestyle intervention in the prevention of type 2 diabetes
Uusitupa M. 2002. DIABETES AND RELATED DISORDERS -
Lifestyles matter in the prevention of type 2 diabetes
Uusitupa M. 2002. Diabetes care -
Lihavuus ja ahmimishäiriö
Rissanen A, Uusitupa M. Teoksessa: Neuvonen PJ , Himberg J-J, Huupponen R, Kivistö KT, Ylitalo P(toim.) , 2002. Kliininen farmakologia ja lääkehoito. s. 428-434. Kandidaattikustannus -
N-3-sarjan rasvahapot suojaavat sepelvaltimotautipotilasta äkkikuolemalta
Erkkilä A, Uusitupa M. 2002. Duodecim -
No harm from five year ingestion of oats in coeliac disease
Janatuinen EK, Kemppainen TA, Julkunen RJK, Kosma V-M, Mäki M, Heikkinen M, Uusitupa MIJ. 2002. Gut. 50: 332-335 -
Non-pharmacological treatment of hypertension in primary health care: a 2-year open randomized controlled trial of lifestyle intervention against hypertension in eastern Finland
Kastarinen MJ, Puska PM, Korhonen MH, Mustonen JN, Salomaa VV, Sundvall JE, Tuomilehto JO, Uusitupa MI, Nissinen AM, for the LIHEF Study Group. 2002. Journal of hypertension. 20: 2505-2512 -
Ravintotekijät säätelevät geenien toimintaa
Hendolin M, Uusitupa M. 2002. Kehittyvä Elintarvike. : 6-7 -
Short-term LDL cholesterol-lowering efficacy of plant stanol esters
Hallikainen M, Sarkkinen E, Wester I, Uusitupa M. 2002. Bmc cardiovascular disorders. 2: 1-14 -
The effect of vegetable oil-based cheese on serum total and lipoprotein lipids
Karvonen HM, Tapola NS, Uusitupa MI, Sarkkinen ES. 2002. European journal of clinical nutrition. 56: 1094-1101 -
The effects of the Pro12Ala polymorphism of the peroxisome proliferator-activated receptor-gamma2 gene on insulin sensitivity and insulin metabolism interact with size at birth
Eriksson JG, Lindi V, Uusitupa M, Forsén TJ, Laakso M, Osmond C, Barker DJP. 2002. Diabetes. 51: 2321-2324 -
The impact of the leucine 7 to proline 7 polymorphism of the neuropeptide Y gene on postprantial lipemia and on the response of serum total and lipoprotein lipids to a reduced fat diet
Schwab US, Ågren JJ, Valve R, Hallikainen MA, Sarkkinen ES, Jauhiainen M, Karvonen MK, Pesonen U, Koulu M, Uusitupa MIJ, Savolainen MJ. 2002. European journal of clinical nutrition. 56: 149-156 -
Variation in the fatty acid binding protein 2 gene is not associated with markers of metabolic syndrome in patients with coronary heart disease
Erkkilä AT, Lindi V, Lehto S, Pyörälä K, Laakso M, Uusitupa MIJ. 2002. Nutrition metabolism and cardiovascular diseases. 12: 53-59 -
APOE polymorphism and the hypertriglyceridemic effect of dietary sucrose 1-3
Erkkilä AT, Sarkkinen ES, Lindi V, Lehto S, Laakso M, Uusitupa MIJ. 2001. American journal of clinical nutrition. 73: 746-752 -
Aikuistyypin diabeteksen ehkäisy - haaste terveydenhuollollemme
Uusitupa M. 2001. DIABETES JA LÄÄKÄRI. 30: 6-7 -
Altered intracellular processing and release of neuropeptide Y due to leucine 7 to proline 7 polymorphism in the signal peptide of preproneuropeptide Y in humans
Kallio J, Pesonen U, Kaipio K, Karvonen MK, Jaakkola U, Heinonen OJ, Uusitupa MIJ, Koulu M. 2001. Faseb journal. 15: 1242-1244 -
Association between manganese superoxide dismutase (MnSOD) gene polymorphism and breast cancer risk
Mitrunen K, Sillanpää P, Kataja V, Eskelinen M, Kosma V-M, Benhamou S, Uusitupa M, Hirvonen A. 2001. Carcinogenesis. 22: 827-829 -
Clustering of cardiovascular risk factors in type 2 diabetes mellitus: prognostic significance and tracking
Kaukua J, Turpeinen A, Uusitupa M, Niskanen L. 2001. Diabetes obesity and metabolism. 3: 17-23 -
D-vitamiini ja eturauhassyöpä
Järvinen R, Uusitupa M. 2001. Lääkärilehti. 56: 3211-3212 -
Effect of a three-amino acid deletion in the alfa2B-adrenergic receptor gene on long-term body weight change in Finnish non-diabetic and type 2 diabetic subjects
Sivenius K, Lindi V, Niskanen L, Laakso M, Uusitupa M. 2001. International journal of obesity. 25: 1609-1614 -
Effect of the Pro12Ala polymorphism of the PPAR-gamma2 gene on lon-term weight change in Finnish non-diabetic subjects
Lindi V, Sivenius K, Niskanen L, Laakso M, Uusitupa MIJ. 2001. Diabetologia -
Effects of ageing on serotonin transporters in healthy females
Kuikka JT, Tammela L, Bergström KA, Karhunen L, Uusitupa M, Tiihonen J. 2001. European journal of nuclear medicine and molecular imaging. 28: 911-913 -
Glutathione S-transferase M1, M3, P1, and T1 genetic polymorphisms and susceptibility to breast cancer
Mitrunen K, Jourenkova N, Kataja V, Eskelinen M, Kosma V-M, Benhamou S, Vainio H, Uusitupa M, Hirvonen A. 2001. Cancer epidemiology biomarkers and prevention. 10: 229-236 -
Leucine7 to proline7 polymorphism in the preproneuropeptide Y is associated with the progression of carotid atherosclerosis, blood pressure and serum lipids in Finnish men
Karvonen MK, Valkonen V-P, Lakka TA, Salonen R, Koulu M, Pesonen U, Tuomainen T-P, Kauhanen J, Nyyssönen K, Lakka H-M, Uusitupa MIJ, Salonen JT. 2001. Atherosclerosis. 159: 145-151 -
Liikunta ja ruokavalio ovat metabolisen oireyhtymän täsmähoitoa
Uusitupa M. 2001. Duodecim. 117: 621-630 -
Maculopathy and visual acuity in newly diagnosed type 2 diabetic patients and non-diabetic subjects: A 10-year follow-up study
Voutilainen-Kaunisto R, Teräsvirta M, Uusitupa M, Niskanen L. 2001. Acta ophthalmologica. 79: 163-168 -
Myocardial fatty acid oxidation in patients with impaired glucose tolerance
Knuuti J, Takala TO, Någren K, Sipilä H, Turpeinen AK, Uusitupa MIJ, Nuutila P. 2001. Diabetologia. 44: 184-187 -
Occurrence and predictors of retinopathy and visual acuity in type 2 diabetic patients and control subjects 10-year follow-up from the diagnosis
Voutilainen-Kaunisto RM, Teräsvirta ME, Uusitupa MIJ, Niskanen LK. 2001. Journal of diabetes and its complications. 15: 24-33 -
Polymorphic GSTs and cancer predisposition
Hirvonen A, Bouchardy C, Mitrunen K, Kataja V, Eskelinen M, Kosma V-M, Saarikoski ST, Jourenkova N, Anttila S, Dayer P, Uusitupa M, Benhamou S. 2001. Chemico-biological interactions. 133: 75-80 -
Polymorphic catechol-O-methyltransferase gene and breast cancer risik
Mitrunen K, Jourenkova N, Kataja V, Eskelinen M, Kosma V-M, Benhamou S, Kang D, Vainio H, Uusitupa M, Hirvonen A. 2001. Cancer epidemiology biomarkers and prevention. 10: 635-640 -
Postprandial responses of individual fatty acids in subjects homozygous for the threonine- or alanine-encoding allele in codon 54 of the intestinal fatty acid binding protein 2 gene 1,2
Ågren JJ, Vidgren HM, Valve RS, Laakso M, Uusitupa MI. 2001. American journal of clinical nutrition. 73: 31-35 -
Prevention of type 2 diabetes mellitus by changes in lifestyle among subjects with impaired glucose tolerance
Tuomilehto J, Lindström J, Eriksson JG, Valle TT, Hämäläinen H, Ilanne-Parikka P, Keinänen-Kiukaanniemi S, Laakso M, Louheranta A, Rastas M, Salminen V, Uusitupa M, for the Finnish Diabetes Prevention Study Group, Hakumäki M. 2001. The new england journal of medicine. 344: 1343-1350 -
Reduced serotonin transporter binding in binge eating women
Kuikka JT, Tammela L, Karhunen L, Rissanen A, Bergström KA, Naukkarinen H, Vanninen E, Karhu J, Lappalainen R, Repo-Tiihonen E, Tiihonen J, Uusitupa M. 2001. Psychopharmacology. 155: 310-314 -
Serum enterolactone and risk of breast cancer: A case-control study in Eastern Finland
Pietinen P, Stumpf K, Männistö S, Kataja V, Uusitupa M, Adlercreutz H. 2001. Cancer epidemiology biomarkers and prevention. 10: 339-344 -
Sterol regulatory element binding protein 1c (SREBP-1c) expression in human obesity
Kolehmainen M, Vidal H, Alhava E, Uusitupa MIJ. 2001. Obesity. 9: 706-712 -
Substituting dietary saturated for monounsaturated fat impairs insulin sensitivity in healthy men and women:The KANWU study
Vessby B, Uusitupa M, Hermansen K, Riccardi G, Rivellese AA, Tapsell LC, Nälsén C, Berglund L, Louheranta A, Rasmussen BM, Calvert GD, Maffetone A, Pedersen E, Gustafsson I-B, Storlien LH. 2001. Diabetologia. 44: 312-319 -
Tyypin 2 diabetes on ehkäistävissä elämäntapamuutoksilla
Valle TT, Lindström J, Eriksson JG, Uusitupa M, Tuomilehto J. 2001. Duodecim -
Weight change and blood coagulability and fibrinolysis in healthy obese women
Rissanen P, Vahtera E, Krusius T, Uusitupa M, Rissanen A. 2001. International journal of obesity. 25: 212-218 -
Yhteistyö sairaanhoitopiirien välillä Suomessa
Uusitupa M, Tuomainen R. 2001. Lääkärilehti. 56: 683-687 -
Aerobic exercise and the lipid profile in type 1 diabetic men: a randomized controlled trial
Laaksonen DE, Atalay M, Niskanen LK, Mustonen J, Sen CK, Lakka TA, Uusitupa MIJ. 2000. Medicine and science in sports and exercise. 32: 1541-1548 -
Age-related macular degeneration in newly diagnosed type 2 diabetic patients and control subjects
Voutilainen-Kaunisto RM, Teräsvirta ME, Uusitupa MIJ, Niskanen LK. 2000. Diabetes care. 23: 1672-1678 -
Aikuistyypin diabeteksen ehkäisy
Louheranta A, Uusitupa M. 2000. Lääkärilehti. 55: 3919-3921 -
Autoantibodies against oxidized low-density lipoprotein and cardiolipin in patients with coronary heart disease
Erkkilä AT, Närvänen O, Lehto S, Uusitupa MIJ, Ylä-Herttuala S. 2000. Arteriosclerosis, thrombosis, and vascular biology. 20: 204-209 -
Comparison of the effects of plant sterol ester and plant stanol ester-enriched margarines in lowering serum cholesterol concentrations in hypercholesterolaemic subjects on low-fat diet
Hallikainen MA, Sarkkinen ES, Gylling H, Erkkilä AT, Uusitupa MIJ. 2000. European journal of clinical nutrition. 54: 715-725 -
Concordance of in vivo microdialysis and in vitro techniques in the studies of adipose tissue metabolism
Kolehmainen M, Ohisalo JJ, Kaartinen JM, Tuononen V, Pääkkönen M, Poikolainen E, Alhava E, Uusitupa MIJ. 2000. International journal of obesity. 24: 1426-1432 -
Effect of orlistat treatment on body composition and resting energy expenditure during a two-year weight -reduction programme in obese Finns
Karhunen L, Franssila-Kallunki A, Rissanen P, Valve R, Kolehmainen M, Rissanen A, Uusitupa M. 2000. International journal of obesity. 24: 1567-1572 -
Effects of a salt-restricted diet on the intake of other nutrients
Korhonen MH, Järvinen RMK, Sarkkinen ES, Uusitupa MIJ. 2000. American journal of clinical nutrition. 72: 414-420 -
Growth, dietary intake, and trace element status in pubescent athletes and schoolchildren
Fogelholm M, Rankinen T, Isokääntä M, Kujala U, Uusitupa M. 2000. Medicine and science in sports and exercise. 32: 738-746 -
Health effects of plant stanol esters
Hallikainen M, Sarkkinen E, Uusitupa M. 2000. FOOD INDUSTRY JOURNAL. 3: 232-238 -
Hyperproinsulinemia is not a charascteristic feature in the offspring of patients with different phenotypes of type II diabetes
Vauhkonen IKJ, Niskanen LK, Mykkänen L, Haffner SM, Uusitupa MIJ, Laakso M. 2000. European journal of endocrinology. 143: 251-260 -
Impaired insulin secretion in non-diabetic offspring of probands with latent autoimmune diabetes mellitus in adults
Vauhkonen I, Niskanen L, Knip M, Ilonen J, Vanninen E, Kainulainen S, Uusitupa M, Laakso M. 2000. Diabetologia. 43: 69-78 -
Insulin sensitivity after a reduced-fat diet and a monoene-ecriched idiet in subjects with elevated serum cholesterol and triglyceride concentrations
Louheranta AM, Schwab US, Sarkkinen ES, Voutilainen ET, Ebeling TML, Erkkilä AT, Turpeinen AK, Uusitupa MIJ. 2000. Nutrition metabolism and cardiovascular diseases. 10: 177-187 -
Kaura ja keliakia. Pitkäaikaistulokset varmistavat kauran sopivuuden
Uusitupa M, Kemppainen T. 2000. Lääkärilehti. 55: 1868-1869 -
Lack of cellular and humoral immunological responses to oats in adults with coeliac disease
Janatuinen EK, Kemppainen TA, Pikkarainen PH, Holm KH, Kosma V-M, Uusitupa MIJ, Mäki M, Julkunen RJK. 2000. Gut. 46: 327-331 -
Leucine 7 to proline 7 polymorphism in the neuropeptide Y gene is associated with enhanced carotid atherosclerosis in elderly patients with type 2 diabetes and control subjects
Niskanen L, Karvonen MK, Valve R, Koulu M, Pesonen UM, Mercuri M, Rauramaa R, Töyry J, Laakso M, Uusitupa MIJ. 2000. Journal of clinical endocrinology and metabolism. 85: 2266-2269 -
Leucine 7 to proline 7 polymorphism in the neuropeptide y gene is associated with retinopathy in Type 2 diabetes
Niskanen L, Voutilainen-Kaunisto R, Teräsvirta M, Karvonen M K, Valve R, Pesonen U, Laakso M, Uusitupa MIJ, Koulu M. 2000. Experimental and clinical endocrinology and diabetes. 108: 235-236 -
Leucine 7 to proline 7 polymorphism in the preproneuropeptide Y is associated with birth weight and serum triglyceride concentration in preschoolaged children
Karvonen MK, Koulu M, Pesonen U, Uusitupa MIJ, Tammi A, Viikari J, Simell O, Rönnemaa T. 2000. Journal of clinical endocrinology and metabolism. 85: 1455-1460 -
Lifetime alcohol consumption and breast cancer: a case-control study in Finland
Männistö S, Virtanen M, Kataja V, Uusitupa M, Pietinen P. 2000. Public health nutrition. 3: 11-18 -
Long-term effect of acetyl-L-carnitine on myocardial 123I-MIBG uptake in patients with diabetes
Turpeinen AK, Kuikka JT, Vanninen E, Yang J, Uusitupa MIJ. 2000. Clinical autonomic research. 10: 13-16 -
Neuropeptide Y polymorphism and alcohol consumption in middle-aged men
Kauhanen J, Karvonen MK, Pesonen U, Koulu M, Tuomainen T-P, Uusitupa MIJ, Salonen JT. 2000. American journal of medical genetics. Part A. 93: 117-121 -
Onko suklaa terveellistä?
Sarkkinen E, Uusitupa M. 2000. Lääkärilehti. 55: 2902-2903 -
Oral symptoms and signs in elderly patients with type 2 diabetes mellitus. A focus on diabetic neuropathy
Collin H-L, Niskanen L, Uusitupa M, Töyry J, Collin P, Koivisto A-M, Viinamäki H, Meurman JH. 2000. Oral surgery oral medicine oral pathology oral radiology and endodontology. 90: 299-305 -
Plant stanol esters affect serum cholesterol concentrations of hyperchlesterolemic men and women in a done-dependent manner
Hallikainen MA, Sarkkinen ES, Uusitupa MIJ. 2000. Journal of nutrition. 130: 767-776 -
Recommendations for the nutritional management of patients with diabetes mellitus
The Diabetes and Nutrition Study Group of the EASD, Uusitupa M. 2000. European journal of clinical nutrition. 54: 353-355 -
Regional cerebral blood flow during exposure to food in obese binge eating women
Karhunen LJ, Vanninen EJ, Kuikka JT, Lappalainen RI, Tiihonen J, Uusitupa MIJ. 2000. Psychiatry research: neuroimaging. 99: 29-42 -
Salivary matrix metalloproteinase (MMP-8) levels and gelatinase (MMP-9) activities in patients with type 2 diabetes mellitus
Collin H-L, Sorsa T, Meurman JH, Niskanen L, Salo T, Rönkä H, Konttinen YT, Koivisto A-M, Uusitupa M. 2000. Journal of periodontal research. 35: 259-265 -
Stanolia, sterolia - mutta kuinka paljon?
Sarkkinen E, Hallikainen M, Uusitupa M. 2000. Lääkärilehti. 55: 846-847 -
Steroid metabolism gene CYP17 polymorpsm and the develpment of breast cancer
Mitrunen K, Jourenkova N, Kataja V, Eskelinen M, Kosma V-M, Benhamou S, Vainio H, Uusitupa M, Hirvonen A. 2000. Cancer epidemiology biomarkers and prevention. 9: 1343-1348 -
Sydänmerkki tutuksi
Uusitupa M. 2000. Lääkärilehti -
Synergistic effect of polymorphisms in uncoupling protein 1 and beta3-adrenergic receptor genes on long-term body weight chance in Finnish type 2 diabetic and non-diabetic control subjects
Sivenius K, Valve R, Lindi V, Niskanen L, Laakso M, Uusitupa M. 2000. International journal of obesity. 24: 514-519 -
The Finnish Diabetes Prevention Study
Uusitupa M, Louheranta A, Lindström J, Valle T, Sundvall J, Eriksson J, Tuomilehto J, on behalf of the Finnish Diabetes Prevention Study Group. 2000. BRITISH JOURNAL OF NUTRITION. SUPPLEMENT. 83: S137-S142 -
The leucine (7)-to-proline (7) polymorphism in the signal peptide of neuropeptide y is not associated with Alzheimer¿s disease or the link apolipoprotein E
Helisalmi S, Valve R, Karvonen MK, Hiltunen M, Pirskanen M, Mannermaa A, Koulu M, Pesonen U, Uusitupa M, Soininen H. 2000. Neuroscience letters. 287: 25-28 -
Tieteellinen ja kliininen työ - yhdessä vai erikseen?
Uusitupa M. Teoksessa: Voipio-Pulkki L-M, Grenman R, Haapamäki M, Lenander-Lumikari M, Mäkinen J, Rautava P, Scheinin M, Vainikainen T(toim.) , 2000. Kliinisen tutkijan opas. s. 27-35. Duodecim -
Toenail selenium and breast cancer - a case-control study in Finland
Männistö S, Alfthan G, Virtanen M, Kataja V, Uusitupa M, Pietinen P. 2000. European journal of clinical nutrition. 54: 98-103 -
Variants in the hepatocyte nuclear factor-1alfa and -4alfa genes in Finnish and Chinese subjects with late-onset type 2 diabetes
Rissanen J, Wang H, Miettinen R, Kärkkäinen P, Kekäläinen P, Mykkänen L, Kuusisto J, Karhapää P, Niskanen L, Uusitupa M, Laakso M. 2000. Diabetes care. 23: 1533-1538 -
A high-trans fatty acid diet and insulin sensitivity in young healthy women
Louheranta AM, Turpeinen AK, Vidgren HM, Schwab US, Uusitupa MIJ. 1999. Metabolism: clinical and experimental. 48: 870-875 -
Adherence to the salt restriction diet among people with mildly elevated blood pressure
Korhonen MH, Litmanen H, Rauramaa R, Väisänen SB, Niskanen L, Uusitupa MIJ. 1999. European journal of clinical nutrition. 53: 880-885 -
Antropometriset mittaukset
Uusitupa M, Fogelholm M. Teoksessa: Aro A, Mutanen M, Uusitupa M(toim.) , 1999. Ravitsemustiede. s. 267-272. Duodecim -
Blood glutathione homeostasis as a determinant of resting and exercise-induced oxidative stress in young men
Laaksonen DE, Atalay M, Niskanen L, Uusitupa M, Hänninen O, Sen CK. 1999. Redox report. 4: 53 - 59 -
Bone recovery after a gluten-free diet: a 5-year follow-up study
Kemppainen T, Kröger H, Janatuinen E, Arnala I, Lamberg-Allardt C, Kärkkäinen M, Kosma V-M, Julkunen R, Jurvelin J, Alhava E, Uusitupa M. 1999. Bone. 25: 355-360 -
Diet and the risk of breast cancer in a case-control study: does the threat of disease have an influence on recall bias?
Männistö S, Pietinen P, Virtanen M, Kataja V, Uusitupa M. 1999. Journal of clinical epidemiology. 52: 429-439 -
Diet in relation to socioeconomic status in patients with coronary heart disease
Erkkilä AT, Sarkkinen ES, Lehto S, Pyörälä K, Uusitupa MIJ. 1999. European journal of clinical nutrition. 52: 662-668 -
Dietary associates of serum total, LDL, and HDL cholesterol and triglycerides in patients with coronary heart disease
Erkkilä AT, Sarkkinen ES, Lehto S, Pyörälä K, Uusitupa MIJ. 1999. Preventive medicine. 28: 558-565 -
Difficulties in changing the diet in relation to dietary fat intake among patients with coronary heart disease
Koikkalainen M, Mykkänen H, Erkkilä A, Julkunen J, Saarinen T, Pyörälä K, Uusitupa M, Lappalainen R. 1999. European journal of clinical nutrition. 53: 120-125 -
Effects of 2 low-fat stanol ester-containing margarines on serum cholesterol concentrations as a part of a low-fat diet in hypercholesterolemic subjects
Hallikainen MA, Uusitupa MIJ. 1999. American journal of clinical nutrition. 69: 403-410 -
Effects of low-fat stanol ester enriched margarines on concentrations of serum carotenoids in subjects with elevated serum cholesterol concentrations
Hallikainen MA, Sarkkinen ES, Uusitupa MIJ. 1999. European journal of clinical nutrition. 53: 966-969 -
Efficacy of plant stanol esters in subjects consuming NCEP diets
Uusitupa M, Hallikainen M. 1999. European heart journal supplements. 1: S91-S95 -
Hyperglykemian lääkehoito ja aikuistyypin diabeteksen ennuste
Niskanen L, Uusitupa M, Laakso M. 1999. Duodecim. 115: 1122-1124 -
Identification of a three-amino acid deletion in the alfa2B-adrenergic receptor that is associated with reduced basal metabolic rate in obese subjects
Heinonen P, Koulu M, Pesonen U, Karvonen MK, Rissanen A, Laakso M, Valve R, Uusitupa M, Scheinin M. 1999. Journal of clinical endocrinology and metabolism. 84: 2429-2433 -
Impaired free fatty acid uptake in skeletal muscle but not in myocardium in patients with impaired glucose tolerance Studies with PET and 14(R, S)-[18F]Fluoro-6-Thia-Heptadecanoic acid
Turpeinen AK, Takala TO, Nuutila P, Axelin T, Luotolahti M, Haaparanta M, Bergman J, Hämäläinen H, Iida H, Mäki M, Uusitupa MIJ, Knuuti J. 1999. Diabetes. 48: 1245-1250 -
Kehon koostumuksen arviointi
Fogelholm M, Uusitupa M. Teoksessa: Aro A, Mutanen M, Uusitupa M(toim.) , 1999. Ravitsemustiede. s. 273-279. Duodecim -
Leptin concentrations and their relation to body fat distribution and weight loss - a prospective study in individuals with impaired glucose tolerance
Eriksson J, Valle T, Lindström J, Haffner S, Louheranta A, Uusitupa M, Tuomilehto J, on behalf of the DPS-study group. 1999. Hormone and metabolic research. 31: 616-619 -
Lihavuus
Uusitupa M. Teoksessa: Aro A, Mutanen M, Uusitupa M(toim.) , 1999. Ravitsemustiede. s. 354-376. Duodecim -
Liikunta, energiankulutus ja ravitsemus
Fogelholm M, Uusitupa M. Teoksessa: Vuori I, Taimela S(toim.) , 1999. Liikuntalääketiede. 2., uud. p.. s. 73-82. Duodecim -
Measurement of prostate-specific antigen in detection of benign or malignant breast disease in women
Romppanen J, Keskikuru R, Kataja V, Eskelinen M, Kosma V-M, Savolainen K, Uusitupa M, Mononen I. 1999. British journal of cancer. 79: 1583-1587 -
Neuropeptidi Y ja veren kolesterolipitoisuus
Uusitupa MIJ, Karvonen MK, Pesonen U, Koulu M. 1999. Duodecim -
New aspects in the management of obesity: operation and the impact of lipase inhibitors
Uusitupa M. 1999. Current opinion in lipidology. 10: 3-7 -
Osteoporosis in adult patients with celiac disease
Kemppainen T, Kröger H, Janatuinen E, Arnala I, Kosma V-M, Pikkarainen P, Julkunen R, Jurvelin J, Alhava E, Uusitupa M. 1999. Bone. 24: 249-255 -
Power spectral analysis of heart rate variability during hyperinsulinemia in nondiabetic offspring of type 2 diabetic patients: evidence for possible early autonomic dysfunction in insulin-resistant subjects
Laitinen T, Vauhkonen IKJ, Niskanen LK, Hartikainen JEK, Länsimies EA, Uusitupa MIJ, Laakso M. 1999. Diabetes. 48: 1295-1299 -
Preoperative high type I collagen degradation marker ICTP reflects advanced breast cancer
Keskikuru R, Kataja V, Kosma V-M, Eskelinen M, Uusitupa M, Johansson R, Risteli L, Risteli J, Jukkola A. 1999. Anticancer research. 19: 4481-4484 -
Prevention of type II diabetes in subjects with impaired glucose tolerance:the Diabetes Prevention Study (DPS) in Finland: study design and 1-year interim report on the feasibility of the lifestyle intervention programme
Eriksson J, Lindström J, Valle T, Aunola S, Hämäläinen H, Ilanne-Parikka P, Keinänen-Kiukaanniemi S, Laakso M, Lauhkonen M, Lehto P, Louheranta A, Mannelin M, Martikkala V, Rastas M, Sundvall J, Turpeinen A, Viljanen T, Uusitupa M, Tuomilehto J. 1999. Diabetologia. 42: 793-801 -
Ravitsemus ja diabetes
Uusitupa M. Teoksessa: Aro A, Mutanen M, Uusitupa M(toim.) , 1999. Ravitsemustiede. s. 377-404. Duodecim -
Ravitsemustilan arviointi
Uusitupa M, Fogelholm M, Nuutinen L. Teoksessa: Aro A, Mutanen M, Uusitupa M(toim.) , 1999. Ravitsemustiede. s. 280-285. Duodecim -
Reply to S Jameson (to Villous atrophy and nutritional status in celiac disease)
Kemppainen TA, Uusitupa MI, Kosma V-M, Julkunen RJ. 1999. American journal of clinical nutrition -
Rye bread decreases postprandial insulin response but does not alter glucose response in healthy Finnish subjects
Leinonen K, Liukkonen K, Poutanen K, Uusitupa M, Mykkänen H. 1999. European journal of clinical nutrition. 53: 262-267 -
Serum leptin and regional cerebral blood flow during exposure to food in obese and normal-weight women
Karhunen LJ, Lappalainen RI, Vanninen EJ, Kuikka JT, Uusitupa MIJ. 1999. Neuroendocrinology. 69: 154-159 -
Sydän- ja keuhkosairauksien ravitsemushoito
Uusitupa M. Teoksessa: Aro A, Mutanen M, Uusitupa M(toim.) , 1999. Ravitsemustiede. s. 522-523. Duodecim -
The effect of orlistat on the fatty acid composition of serum lipid fractions in obese subjects
Vidgren HM, Ågren JJ, Valve RS, Karhunen LJ, Rissanen AM, Uusitupa MIJ. 1999. Clinical pharmacology and therapeutics. 66: 315-322 -
Two polymorphisms in the peroxisome proliferator-activated receptor-gamma gene are associated with severe overweight among obese women
Valve R, Sivenius K, Miettinen R, Pihlajamäki J, Rissanen A, Deeb SS, Auwerx J, Uusitupa M, Laakso M. 1999. Journal of clinical endocrinology and metabolism. 84: 3708-3712 -
A high-stearic acid diet does not impair glucose tolerance and insulin sensitivity in healthy women
Louheranta AM, Turpeinen AK, Schwab US, Vidgren HM, Parviainen MT, Uusitupa MIJ. 1998. Metabolism: clinical and experimental. 47: 529-534 -
Aineenvaihdunnan ja ravitsemuksen häiriöt: diabetes
Uusitupa M. Teoksessa: Koskenvuo K, Vertio H(toim.) , 1998. Sairauksien ehkäisy. s. 177-184. Duodecim -
Aineenvaihdunnan ja ravitsemuksen häiriöt: lihavuus
Uusitupa M. Teoksessa: Koskenvuo K, Vertio H(toim.) , 1998. Sairauksien ehkäisy. s. 171-177. Duodecim -
Association of a leucine(7)-to-proline(7) polymorphism in the signal peptide of neuropeptide Y with high serum cholesterol and LDL cholesterol levels
Karvonen MK, Pesonen U, Koulu M, Niskanen L, Laakso M, Rissanen A, Dekker JM, ¿T Hart LM, Valve R, Uusitupa MIJ. 1998. Nature medicine. 4: 1434-1437 -
Caries in patients with non-insulin-dependent diabetes mellitus
Collin H-L, Uusitupa M, Niskanen L, Koivisto A-M, Markkanen H, Meurman JH. 1998. Oral surgery oral medicine oral pathology oral radiology and endodontology. 85: 680-685 -
Concordance of diet with the recommended cholesterol lowering diet in patients with coronary heart disease
Erkkilä AT, Sarkkinen ES, Koukkunen H, Kemppainen A, Lehto S, Pyörälä K, Uusitupa MIJ. 1998. European journal of clinical nutrition. 52: 279-285 -
Defects in insulin secretion and insulin action in non-insulin-dependent diabetes mellitus are inherited: metabolic studies on offspring of diabetic probands
Vauhkonen I, Niskanen L, Vanninen E, Kainulainen S, Uusitupa M, Laakso M. 1998. Journal of clinical investigation. 101: 86-96 -
Divergent incorporation of dietary trans fatty acids in different serum lipid fractions
Vidgren HM, Louheranta AM, Ågren JJ, Schwab US, Uusitupa MIJ. 1998. Lipids. 33: 955-962 -
Early intervention in obesity: implications for impaired glucose tolerance and type II diabetes
Uusitupa M, Van Gaal L. 1998. EUROPEAN JOURNAL OF CLINICAL INVESTIGATION. SUPPLEMENT -
Effect of apolipoprotein E polymorphism on serum lipid response to the separate modification of dietary fat and dietary cholesterol 1-3
Sarkkinen E, Korhonen M, Erkkilä A, Ebeling T, Uusitupa M. 1998. American journal of clinical nutrition. 68: 1215-1222 -
Fat-modified diets influence serum concentrations of cholesterol precursors and plant sterols in hypercholesterolemic subjects
Sarkkinen ES, Uusitupa MIJ, Gylling H, Miettinen TA. 1998. Metabolism: clinical and experimental. 47: 744-750 -
Hyperglycemia and compositional lipoprotein abnormalities as predictors of cardiovascular mortality in type 2 diabetes: a 15-year follow-up from the time of diagnosis
Niskanen L, Turpeinen A, Penttilä I, Uusitupa MIJ. 1998. Diabetes care. 21: 1861-1869 -
Hypo-cholesterolaemic effects of dietary fibre in relation to genetic factors
Uusitupa M. Teoksessa: Guillon E, Amado R et al.(toim.) , 1998. Functional Properties of Non-Digestible Carbohydrates. European Air Concerted Action AIR3CT94-2203. s. 97-100. European Commission -
Identification of new sequence variants in the leptin gene
Karvonen MK, Pesonen U, Heinonen P, Laakso M, Rissanen A, Naukkarinen H, Valve R, Uusitupa MIJ, Koulu M. 1998. Journal of clinical endocrinology and metabolism. 83: 3239-3242 -
Insulin resistant phenotype is associated with high serum leptin levels in offspring of patients with non-insulin-dependent diabetes mellitus
Vauhkonen I, Niskanen L, Haffner S, Kainulainen S, Uusitupa M, Laakso M. 1998. European journal of endocrinology. 139: 598-604 -
Kost som prevention mot fetma
Uusitupa M. Teoksessa: Andersen T, Rissanen A, Rössner S (red.)(toim.) , 1998. Fetma/fedme - en nordisk lärobok. s. 325-330. Studentlitteratur -
Lihavan potilaan tutkiminen ja hoitomuodon valinta
Mustajoki P, Rissanen A, Uusitupa M. Teoksessa: Fogelholm M, Mustajoki P, Rissanen A, Uusitupa M(toim.) , 1998. Lihavuus: ongelma ja hoito. 2. uud. p.. s. 103-107. Duodecim -
Lihavuuden syyt
Rissanen A, Uusitupa M. Teoksessa: Fogelholm M, Mustajoki P, Rissanen A, Uusitupa M(toim.) , 1998. Lihavuus: ongelma ja hoito. 2. uud. p.. s. 89-91. Duodecim -
Lihavuus ja terveys
Uusitupa M. Teoksessa: Fogelholm M, Mustajoki P, Rissanen A, Uusitupa M(toim.) , 1998. Lihavuus : ongelma ja hoito. 2. uud. p.. s. 19-28. Duodecim -
Mäkihyppääjien ravitsemustila - kevyempänä lentää kauemmaksi
Uusitupa M. 1998. Lääkärilehti. 53: 836-837 -
Neuropeptide Y: a novel link between the neuroendocrine system and cholesterol metabolism
Uusitupa MIJ, Karvonen MK, Pesonen U, Koulu M. 1998. Annals of medicine -
Nutritional status of newly diagnosed celiac disease patients before and after the institution of a celiac disease diet - association with the grade of mucosal villous atrophy1-3
Kemppainen TA, Kosma V-M, Janatuinen EK, Julkunen RJ, Pikkarainen PH, Uusitupa MI. 1998. American journal of clinical nutrition. 67: 482-487 -
Nutritional status of the Finnish elite ski jumpers
Rankinen T, Lyytikäinen S, Vanninen E, Penttilä I, Rauramaa R, Uusitupa M. 1998. Medicine and science in sports and exercise. 30: 1592-1597 -
Perimä ja lihavuus
Uusitupa M. Teoksessa: Fogelholm M, Mustajoki P, Rissanen A, Uusitupa M(toim.) , 1998. Lihavuus: ongelma ja hoito. 2. uud. p.. s. 60-69. Duodecim -
Periodontal findings in elderly patients with non-insulin dependent diabetes mellitus
Collin H-L, Uusitupa M, Niskanen L, Kontturi-Närhi V, Markkanen H, Koivisto A-M, Meurman JH. 1998. Journal of periodontology. 69: 962-966 -
Postprandial lipemic response is modified by the polymorphism at codon 54 of the fatty acid-binding protein 2 gene
Ågren JJ, Valve R, Vidgren H, Laakso M, Uusitupa M. 1998. Arteriosclerosis, thrombosis, and vascular biology. 18: 1606-1610 -
Randomised placebo-controlled trial of orlistat for weight loss and prevention of weight regain in obese patients
Sjöström L, Rissanen A, Andersen T, Boldrin M, Golay A, Koppeschaar HPF, Krempf M, for the European Multicentre Orlistat Group, Uusitupa M. 1998. The Lancet. 352: 167-173 -
Risk factors of cardiovascular disease in the elderly
Uusitupa MIJ, Sarkkinen ES. 1998. Nutrition metabolism and cardiovascular diseases. 8: 341-348 -
Saliva in non-insulin-dependent diabetic patients and control subjects: the role of the autonomic nervous system
Meurman JH, Collin H-L, Niskanen L, Töyry J, Alakuijala P, Keinänen S, Uusitupa M. 1998. Oral surgery oral medicine oral pathology oral radiology and endodontology. 86: 69-76 -
Sepelvaltimotaudin sekundaariprevention toteutuminen KYS:ssa hoidetuilla potilailla: EUROASPIRE-tutkimuksen tuloksia
Koukkunen H, Kemppainen A, Lehto S, Erkkilä A, Sarkkinen E, Uusitupa M, Pyörälä K. 1998. Lääkärilehti. 53: 2029-2041 -
Serum leptin, food intake and preferences for sugar and fat in obese women
Karhunen LJ, Lappalainen RI, Haffner SM, Valve RH, Tuorila H, Miettinen H, Uusitupa MIJ. 1998. International journal of obesity. 1998: 819-821 -
Synergistic effect of polymorphisms in uncoupling protein 1 and beta3-adrenergic receptor genes on basal metabolic rate in obese Finns
Valve R, Heikkinen S, Rissanen A, Laakso M, Uusitupa M. 1998. Diabetologia. 41: 357-361 -
The effect of a very low-calorie diet-induced weight loss on the severity of obstructive sleep apnoea and autonomic nervous function in obese patients with obstructive sleep apnoea syndrome
Kansanen M, Vanninen E, Tuunainen A, Pesonen P, Tuononen V, Hartikainen J, Mussalo H, Uusitupa M. 1998. Clinical physiology and functional imaging. 18: 377-385 -
The effect of quality and amount of dietary fat on the susceptibility of low density lipoprotein to oxidation in subjects with impaired glucose tolerance
Schwab US, Sarkkinen ES, Lichtenstein AH, Li Z, Ordovas JM, Schaefer EJ, Uusitupa MIJ. 1998. European journal of clinical nutrition. 52: 452-458 -
Abnormal myocardial kinetics of 123I-heptadecanoic acid in subjects with impaired glucose tolerance
Turpeinen AK, Kuikka JT, Vanninen E, Uusitupa MIJ. 1997. Diabetologia. 40: 541-549 -
Altered antioxidant enzyme defences in insulin-dependent diabetic men with increased resting and exercise-induced oxidative stress
Atalay M, Laaksonen DE, Niskanen L, Uusitupa M, Hänninen O, Sen CK. 1997. Acta physiologica. 161: 195-201 -
Changes in autonomic nervous function during the 4-year follow-up in middle-aged diabetic and nondiabetic subjects initially free of coronary heart disease
Mustonen J, Uusitupa M, Mäntysaari M, Länsimies E, Pyörälä K, Laakso M. 1997. Journal of internal medicine. 241: 227-235 -
Determinants of resting energy expenditure in obese non-diabetic caucasian women
Karhunen L, Franssila-Kallunki A, Rissanen A, Kervinen K, Kesäniemi YA, Uusitupa M. 1997. International journal of obesity. 21: 197-202 -
Diabetesnefropati - screening, uppföljning och behandling
Koivisto V, Groop PH, Huttunen N-P, Kivekäs J, Pasternack A, Uusitupa M, Viikari J. 1997. NORDISK MEDICIN. 112: 154-162 -
Divergent association of apolipoprotein E polymorphism with vascular disease in patients with NIDDM and control subjects
Vauhkonen I, Niskanen L, Ryynänen M, Voutilainen R, Partanen J, Töyry J, Mercuri M, Rauramaa R, Uusitupa M. 1997. Diabetic medicine. 14: 748-756 -
Divergent development of autonomic and peripheral somatic neuropathies in NIDDM
Töyry JP, Partanen JVS, Niskanen LK, Länsimies EA, Uusitupa MIJ. 1997. Diabetologia. 40: 953-958 -
Do high proinsulin and C-peptide levels play a role in autonomic nervous dysfunction? Power spectral analysis in patients with non-insulin-dependent diabetes and nondiabetic subjects
Töyry JP, Niskanen LK, Mäntysaari MJ, Länsimies EA, Haffner SM, Miettinen HJJ, Uusitupa MIJ. 1997. Circulation. 96: 1185-1191 -
Effects of dietary fat modification on fibrinogen, factor VII, and plasminogen activator inhibitor-1 activity in subjects with impaired glucose tolerance
Niskanen L, Schwab US, Sarkkinen ES, Krusius T, Vahtera E, Uusitupa MIJ. 1997. Metabolism: clinical and experimental. 46: 666-672 -
Incorporation of n-3 fatty acids into plasma lipid fractions, and erythrocyte membranes and platelets during dietary supplementation with fish, fish oil, and docosahexaenoic acid-rich oil among healthy young men
Vidgren HM, Ågren JJ, Schwab U, Rissanen T, Hänninen O, Uusitupa MIJ. 1997. Lipids. 32: 697-705 -
Kaura ja keliakia
Janatuinen E, Julkunen R, Uusitupa M. 1997. Duodecim -
Keliakian hoitosuositus
Suomen Gastroenterologiayhdistys Ry, Uusitupa M, Julkunen R. 1997. Duodecim. 113: [6] -
Lathosterol and other non-cholesterol sterols during treatment of hypercholesteroleamia with beta-glucan-rich oat bran
Uusitupa MIJ, Miettinen TA, Sarkkinen ES, Ruuskanen E, Kervinen K, Kesäniemi YA. 1997. European journal of clinical nutrition. 51: 607-611 -
Lihavan potilaan tutkiminen ja hoitomuodon valinta
Mustajoki P, Rissanen A, Uusitupa M. Teoksessa: Fogelholm M, Mustajoki P, Rissanen A, Uusitupa M(toim.) , 1997. Lihavuus. Ongelma ja hoito. s. 88-92. Duodecim -
Lihavuuden syyt
Rissanen A, Uusitupa M. Teoksessa: Fogelholm M, Mustajoki P, Rissanen A, Uusitupa M(toim.) , 1997. Lihavuus. Ongelma ja hoito. s. 56-67. Duodecim -
Lihavuus ja terveys
Uusitupa M. Teoksessa: Fogelholm M, Mustajoki P, Rissanen A, Uusitupa M(toim.) , 1997. Lihavuus.Ongelma ja hoito. s. 15-25. Duodecim -
Mahapantaleikkaus - sairaalloisen lihavuuden uusi hoitomuoto
Pirinen E, Uusitupa M, Tuononen V, Poikolainen E, Pääkkönen M, Alhava E. 1997. Duodecim. 113: 1471-1475 -
Metabolic effects of diets rich in saturated and omega-6 polyunsatured fatty acids in healthy young females
Schwab US, Karhapää P, Sarkkinen ES, Salminen I, Laakso M, Uusitupa MIJ. 1997. DIABETES, NUTRITION & METABOLISM. 10: 35-38 -
Miten aikuisiän diabeteksen hoitotuloksia voitaisiin parantaa
Uusitupa M. 1997. Lääkärilehti -
Palmitic and stearic acid enriched diets have similar effects on glucose metabolism in healthy young females
Schwab US, Niskanen L, Uusitupa MIJ. 1997. Nutrition metabolism and cardiovascular diseases. 7: 315-319 -
Polymorphism of the Beta3-adrenergic receptor gene affects basal metabolic rate in obese Finns
Sipiläinen R, Uusitupa M, Heikkinen S, Rissanen A, Laakso M. 1997. Diabetes. 46: 77-80 -
Ravinto,terveytemme perusta nyt ja tulevaisuudessa
Uusitupa M, Aro A, Mykkänen H, Rissanen A. 1997. Lääkärilehti. 52: 2181-2186 -
Regional cerebral blood flow during food exposure in obese and normal-weight womem
Karhunen LJ, Lappalainen RI, Vanninen EJ, Kuikka JT, Uusitupa MIJ. 1997. Brain. 120: 1675-1684 -
Relationship of metabolic variables to abdominal adiposity measured by different anthropometric measurements and dual-energy X-ray absorptiometry in obese middle-aged women
Rissanen P, Hämäläinen P, Vanninen E, Tenhunen-Eskelinen M, Uusitupa M. 1997. International journal of obesity. 21: 367-371 -
Satellite Symposium on Nutrition, Obesity and Diabetes
Uusitupa M. 1997. Kuopio University Publications D. Medical Sciences. . - -
Serum leptin and short-term regulation of eating in obese women
Karhunen L, Haffner S, Lappalainen R, Turpeinen A, Miettinen H, Uusitupa M. 1997. Clinical science. 92: 573-578 -
Serum leptin in obesity is related to gender and body fat topography but does not predict successful weight loss
Niskanen LK, Haffner S, Karhunen LJ, Turpeinen AK, Miettinen H, Uusitupa MIJ. 1997. European journal of endocrinology. 137: 61-67 -
Serum leptin in relation to resting energy expenditure and fuel metabolism in obese subjects
Niskanen L, Haffner S, Karhunen LJ, Turpeinen AK, Miettinen H, Uusitupa MIJ. 1997. International journal of obesity. 21: 309-313 -
Serum leptin in subjects with impaired glucose tolerance in relation to insulin sensitivity and first-phase insulin responce
Turpeinen AK, Haffner SM, Louheranta AM, Niskanen LK, Miettinen H, Uusitupa MIJ. 1997. International journal of obesity. 21: 284-287 -
Subjective and physiological cephalic phase responses to food in obese binge-eating women
Karhunen LJ, Lappalainen RI, Tammela L, Turpeinen AK, Uusitupa MIJ. 1997. International journal of eating disorders. 21: 321-328 -
Threonine allele in codon 54 of the fatty acid binding protein 2 gene does not modify the fatty acid composition of serum lipids in obese subjects
Vidgren HM, Sipiläinen RH, Heikkinen S, Laakso M, Uusitupa MIJ. 1997. European journal of clinical investigation. 27: 405-408 -
Variants in the human intestinal fatty acid binding protein 2 gene in obese subjects
Sipiläinen R, Uusitupa M, Heikkinen S, Rissanen A, Laakso M. 1997. Journal of clinical endocrinology and metabolism. 82: 2629-2632 -
Aikuistyypin diabeteksen ehkäisylle on vankat perusteet
Uusitupa M. 1996. DIABETES (LÄÄKÄRILIITE, HELMIKUU) -
Aikuistyypin diabeteksen hoidon periaatteet - repetitio mater studiorum est
Uusitupa M. 1996. Lääkärilehti. 51: 1065-1067 -
Apolipoprotein E phenotype modifies metabolic and hemodynamic abnormalities related to central obesity in women 1-3
Uusitupa MIJ, Karhunen L, Rissanen A, Franssila-Kallunki A, Niskanen L, Kervinen K, Kesäniemi YA. 1996. American journal of clinical nutrition. 64: 131-136 -
Apolipoprotein E phenotypes and response to dietary fat and cholesterol
Kesäniemi YA, Savolainen MJ, Uusitupa M, Sarkkinen E, Rantala M, Kervinen K. Teoksessa: Bray GA, Ryan DH(toim.) , 1996. Nutrition, Genetics, and Heart Disease. s. 379-387. Louisiana State University Press -
Athletic heart: a metabolic, anatomical, and functional study
Turpeinen AK, Kuikka JT, Vanninen E, Vainio P, Vanninen R, Litmanen H, Koivisto VA, Bergström K, Uusitupa MIJ. 1996. Medicine and science in sports and exercise. 28: 33-40 -
Autoantibodies against oxidized LDL do not predict atherosclerotic vascular disease in non-insulin-dependent diabetes mellitus
Uusitupa MIJ, Niskanen L, Luoma J, Vilja P, Mercuri M, Rauramaa R, Ylä-Herttuala S. 1996. Arteriosclerosis, thrombosis, and vascular biology. 16: 1236-1242 -
Autonomic neuropathy predicts the development of stroke in patients with non-insulin-dependent diabetes mellitus
Töyry JP, Niskanen LK, Länsimies EA, Partanen KPL, Uusitupa MIJ. 1996. Stroke. 27: 1316-1318 -
Body-size indicators and risk of breast cancer according to menopause and estrogen-reseptor status
Männistö S, Pietinen P, Pyy M, Palmgren J, Eskelinen M, Uusitupa M. 1996. International journal of cancer. 68: 8-13 -
Carotid artery intima-media thickness in elderly patients with NIDDM and in nondiabetic subjects
Niskanen L, Rauramaa R, Miettinen H, Haffner SM, Mercuri M, Uusitupa M. 1996. Stroke. 27: 1986-1992 -
Demonstration of regional sympathetic denervation of the heart in diabetes
Turpeinen AK, Vanninen E, Kuikka JT, Uusitupa MIJ. 1996. Diabetes care. 19: 1083-1090 -
Determinants of the cephalic-phase insulin response in obese nondiabetic subjects
Karhunen LJ, Lappalainen RI, Niskanen LK, Turpeinen AK, Uusitupa MIJ. 1996. Metabolism: clinical and experimental. 45: 168-173 -
Diabeettinen nefropatia-seulonta, seuranta ja hoito 1996
Suomen Diabetesliiton nefropatiatyöryhmä, Uusitupa M. 1996. Lääkärilehti. 51: 2479-2489 -
Diabetestutkimuksen näkymiä
Uusitupa M. 1996. DIABETES (LÄÄKÄRILIITE, JOULUKUU). 48: 3-5 -
Different effects of palmitic and stearic acid-enriched diets on serum lipids and lipoproteins and plasma cholesterol ester transfer protein activity in healthy young women
Schwab US, Maliranta HM, Sarkkinen ES, Savolainen MJ, Kesäniemi YA, Uusitupa MIJ. 1996. Metabolism: clinical and experimental. 45: 143-149 -
Does lactose intolerance predispose to low bone density? A population-based study of perimenopausal Finnish women
Honkanen R, Pulkkinen P, Järvinen R, Kröger H, Lindstedt K, Tuppurainen M, Uusitupa M. 1996. Bone. 19: 23-28 -
Early lifestyle intervention in patients with non-insulin-dependent diabetes mellitus and impaired glucose tolerance
Uusitupa MIJ. 1996. Annals of medicine. 28: 445-449 -
Effects of moderate salt restriction alone and in combination with cilazapril on office and ambulatory blood pressure
Uusitupa M, Korhonen M, Litmanen H, Niskanen L, Väisänen S, Rauramaa R. 1996. Journal of human hypertension. 10: 319-326 -
Hemodialyysipotilaiden ravitsemustila
Alakärppä S, Nuutinen O, Lampainen E, Uusitupa M. 1996. Duodecim. 112: 986-993 -
Increased resting and excercise-indused oxidative stress in young IDDM men
Laaksonen DE, Atalay M, Niskanen L, Uusitupa M, Hänninen O, Sen CK. 1996. Diabetes care. 19: 569-574 -
Lääkkeettömät keinot aikuistyypin diabeteksen ehkäisyssä
Uusitupa M. 1996. DIABETES (LÄÄKÄRILIITE, HELMIKUU). 48: 13-16 -
Measurement of myocardial accumulation of 123I-metaiodobenzylguanidine for studying cardiac autonomic neuropathy in diabetes mellitus
Mäntysaari M, Kuikka J, Mustonen J, Tahvanainen K, Vanninen E, Länsimies E, Uusitupa M. 1996. Clinical autonomic research. 6: 163-169 -
Metabolic control and macrovascular disease
Uusitupa M. Teoksessa: Alberti P,Zimmet RA,DeFronzo, Keen H(toim.) , 1996. International Textbook of Diabetes Mellitus, Second Edition. s. 1-17. K.G.M.M -
Onko kalarasvalla ja n-3-sarjan monityydyttymättömillä rasvahapoilla merkitystä sairauksien ehkäisyssä ja hoidossa?
Sarkkinen E, Uusitupa M. 1996. Duodecim. 112: 1755-1763 -
Ravitsemusneuvonnasta lisäpotkua diabeetikon hoitoon
Uusitupa M. 1996. DIABETES (LÄÄKÄRILIITE, HUHTIKUU) -
Sepelvaltimotaudin ehkäisy käytännön lääkärintyössä
Suomen Sisätautilääkärien yhdistyksen, Suomen Kardiologisen seuran, Suomen Verenpaineyhdistyksen, Kunnallislääkärit-yhdistyksen, Suomen Teollisuuslääketieteen yhdistyksen ja Suomen Sydäntautiliiton työryhmä, Pyörälä K, Uusitupa M. 1996. Lääkärilehti. 51: 783-802 -
The authors reply (to Oats in celiac disease)
Janatuinen EK, Julkunen RJK, Uusitupa MI. 1996. The new england journal of medicine -
The effects of monounsaturated-fat enriched diet and polyunsaturated-fat enriched diet on lipid and glucose metabolism in subjects with impaired glucose tolerance
Sarkkinen E, Schwab U, Niskanen L, Hannuksela M, Savolainen M, Kervinen K, Kesäniemi A, Uusitupa MIJ. 1996. European journal of clinical nutrition. 50: 592-598 -
The effects of weight loss on insulin sensitivity, skeletal muscle composition and capillary density in obese non-diabetic subjects
Niskanen L, Uusitupa M, Sarlund H, Siitonen O, Paljärvi L, Laakso M. 1996. International journal of obesity. 20: 154-160 -
The nutritional status of Finnish home-living elderly people and the relationship between energy intake and chronic diseases
Rissanen PM, Laakkonen EI, Suntioinen S, Penttilä IM, Uusitupa MI. 1996. Age and ageing. 25: 133-138 -
Troglitazone, an insulin action enhancer, improves metabolic control in NIDDM patients
Kumar S, Boulton AJM, Beck-Nielsen H, Berthezene F, Muggeo M, Persson B, Spinas GA, Donoghue S, Lettis S, Stewart-Long P, for the Troglitazone study group, Uusitupa M. 1996. Diabetologia. 39: 701-709 -
Ventricular repolarization is correlated with metabolic control in newly diagnosed type 2 diabetes
Vanninen E, Uusitupa MIJ, Länsimies E. 1996. Clinical physiology and functional imaging. 16: 449-461 -
Vitamin E concentration in breast adipose tissue of breast cancer patients (Kuopio, Finland)
Zhu Z, Parviainen M, Männistö S, Pietinen P, Eskelinen M, Syrjänen K, Uusitupa M. 1996. Cancer causes and control. 7: 591-595 -
A comparison of diets with and without oats in adults with celiac disease
Janatuinen EK, Pikkarainen PH, Kemppainen TA, Kosma V-M, Järvinen RMK, Uusitupa MIJ, Julkunen RJK. 1995. The new england journal of medicine. 333: 1033-1037 -
Aikuistyypin diabeteksen hoitosuositus uusittu
Uusitupa M. 1995. Lääkärilehti -
Dietary intake and nutritional status of athletic and nonathletic children in early puberty
Rankinen T, Fogelholm M, Kujala U, Rauramaa R, Uusitupa M. 1995. International journal of sport nutrition and exercise metabolism. 5: 136-150 -
Energiestoffwechsel bei typ-II-(non-insulindependent) Diabetes mellitus und Adipositas
Uusitupa M. 1995. DIABETES UND STOFFWECHSEL. 4: 263-264 -
Fatty acid composition of breast adipose tissue in breast cancer patients and in patients with bening breast disease
Zhu ZR, Ågren J, Männistö S, Pietinen P, Eskelinen M, Syrjänen K, Uusitupa M. 1995. Nutrition and cancer: an international journal. 24: 151-160 -
GAD antibodies in NIDDM. Ten-year follow-up from the diagnosis
Niskanen LK, Tuomi TM, Karjalainen J, Groop LC, Uusitupa MIJ. 1995. Diabetes care. 18: 1557-1565 -
Hyperglycemia and cardiovascular risk in NIDDM
Uusitupa MIJ, Niskanen LK. 1995. Diabetes care -
Hyperkolesterolemian hoito lääkäreiden ilmoituksen mukaan vuosina 1985 ja 1992
Nissinen A, Enlund H, Korhonen M, Uusitupa M, Niskanen L, Lempiäinen-Kuosa P, Tuomilehto J. 1995. Lääkärilehti. 50: 2003-2006 -
Intakes of nutrients and nutritional status in coeliac patients
Kemppainen T, Uusitupa M, Janatuinen E, Järvinen R, Julkunen R, Pikkarainen P. 1995. Scandinavian journal of gastroenterology. 30: 575-579 -
Kauraa keliaakikoille
Uusitupa M. 1995. Lääkärilehti. 50: 3476-3477 -
Lauric and palmitic acid-enriched diets have minimal impact on serum lipid and lipoprotein concentrations and glucose metabolism in healthy young women
Schwab US, Niskanen LK, Maliranta HM, Savolainen MJ, Kesäniemi YA, Uusitupa MIJ. 1995. Journal of nutrition. 125: 466-473 -
Liikunta, energiankulutus ja ravitsemus
Fogelholm M, Uusitupa M. Teoksessa: Vuori I, Taimela S(toim.) , 1995. Liikuntalääketiede. s. 69-79. Duodecim -
Mental well-being in people with non-insulin-dependent diabetes
Viinamäki H, Niskanen L, Uusitupa M. 1995. Acta psychiatrica scandinavica. 92: 392-397 -
Metabolinen oireyhtymä
Uusitupa M. 1995. KÄYTÄNNÖN LÄÄKÄRI. 4: 147-151 -
Miten ehkäistä diabeetikon koronaaritautia?
Uusitupa M. 1995. DIABETES JA LÄÄKÄRI. : 7,11 -
Mitä rasvaa leivän päälle?
Uusitupa M, Sarkkinen E. 1995. Duodecim -
Myocardial sympathetic nervous dysfunction detected with iodine-123-MIBG is associated with low heart rate variability after myocardial infarction
Mäntysaari M, Kuikka J, Hartikainen J, Mustonen J, Mussalo H, Tahvanainen K, Länsimies E, Uusitupa M, Pyörälä K. 1995. Journal of nuclear medicine. 36: 956-961 -
Natural history of peripheral neuropathy in patients with non-insulin-dependent diabetes mellitus
Partanen J, Niskanen L, Lehtinen J, Mervaala E, Siitonen O, Uusitupa M. 1995. The new england journal of medicine. 333: 89-94 -
Plasma lipid peroxidation and hyperglycaemia: a connection trough hyperinsulinaemia?
Niskanen LK, Salonen JT, Nyyssönen K, Uusitupa MIJ. 1995. Diabetic medicine. 12: 802-808 -
Ravitsemustilan arviointi käytännön potilastyössä
Uusitupa M, Nuutinen L. 1995. Lääkärilehti. 50: 888-889 -
Recommendations for the nutritional management of patients with diabetes mellitus
Slama G, Lean M, Mann J, Toeller M, Chantelau E, Van Gaal L, Heine R, Karamantos B, Karlstrom B, De Leeuw I, Librenti M, Riccardi G, Rivellese A, Teuscher A, Uusitupa M, Vessby B. 1995. DIABETES, NUTRITION & METABOLISM. 8: 1-4 -
Short-term and long-term memory in elderly patients with NIDDM
Helkala E-L, Niskanen L, Viinamäki H, Partanen J, Uusitupa M. 1995. Diabetes care. 18: 681-685 -
Tehostettu ravitsemushoito
Nuutinen L, Uusitupa M. 1995. Lääkärilehti. 50: 1991-1993 -
The role of rye in Finnish diet
Mykkänen H, Sipiläinen R, Uusitupa M. Teoksessa: Poutanen K, Autio K(toim.) , 1995. International Rye Symposium: Technology and Products, VTT Symposium 161. s. 77-82. Technical Research Centre of Finland -
Uniapneapotilaiden laihdutus ja autonomisen hermoston toiminta
Pesonen PHM, Vanninen E, Tuononen V, Tuunainen A, Kansanen M, Hartikainen J, Mussalo H, Uusitupa M. 1995. Duodecim. 111: 1136-1140 -
Vitamin A concentration in breast adipose tissue of breast cancer patients
Zhu ZR, Parviainen M, Männistö S, Pietinen P, Eskelinen M, Syrjänen K, Uusitupa M. 1995. Anticancer research. 15: 1593-1596 -
Aikuistyypin diabetes: Hyperglykemia ja elinkomplikaatiot
Uusitupa M. 1994. DIABETES (LÄÄKÄRILIITE, HELMIKUU). 2: 10-17 -
Apolipoprotein E phenotype and blood pressure
Uusitupa M, Sarkkinen E, Kervinen K, Kesäniemi YA. 1994. The Lancet. 343: 57 -
Apoprotein (a) is not a predictor of cardiovascular events in elderly patients with Type 2 (non-insulin-dependent) diabetes
Niskanen L, Mykkänen L, Uusitupa M, Karonen S-L. 1994. CARDIOVASCULAR RISK FACTORS. 4: 71-73 -
Cholesterol synthesis in humans
Uusitupa M. Teoksessa: Lairon D(toim.) , 1994. Mechanisms of action of dietary fibre on lipid and cholesterol metabolism. Proceedings of a Workshop Held. s. 71-75. Commission of the European Communities -
Do genetic markers modify serum cholesterol lowering effects of dietary fiber?
Uusitupa M. Teoksessa: Lairon D(toim.) , 1994. Mechanisms of action of dietary fibre on lipid and cholesterol metabolism. Proceedings of a Workshop Held. s. 159-161. Commission of the European Communities -
Effects of two high-fat diets with different fatty acid compositions on glucose and lipid metabolism in healthy young women
Uusitupa M, Schwab U, Mäkimattila S, Karhapää P, Sarkkinen E, Maliranta H, Ågren J, Penttilä I. 1994. American journal of clinical nutrition. 59: 1310-1316 -
Enteraalinen vai parenteraalinen ravitsemus?
Nuutinen L, Uusitupa M. 1994. Duodecim. 110: 1935-1943 -
Fatty acid composition of serum cholesterol esters, and erythrocyte and platelet membranes as indicators of long-term adherence to fat-modified diets
Sarkkinen ES, Ågren JJ, Ahola I, Ovaskainen M-L, Uusitupa MIJ. 1994. American journal of clinical nutrition. 59: 364-70 -
Fructose in the diabetic diet
Uusitupa MIJ. 1994. American journal of clinical nutrition. 59: 753S-757S -
Long-term effects of four fat-modified diets on blood pressure
Uusitupa MIJ, Sarkkinen ES, Torpström J, Pietinen P, Aro A. 1994. Journal of human hypertension. 8: 209-218 -
Long-term effects of three fat-modified diets in hypercholesterolemic subject
Sarkkinen ES, Uusitupa MIJ, Pietinen P, Aro A, Ahola I, Penttilä I, Kervinen K, Kesäniemi YA. 1994. Atherosclerosis. 105: 9-23 -
Metabolic and dietary variables associated with glycaemic control in patients with recently diagnosed Type II diabetes mellitus
Laitinen J, Uusitupa M, Ahola I, Laakso M, Siitonen O. 1994. DIABETES, NUTRITION & METABOLISM. 7: 77-87 -
Metabolic and dietery determinants of serum lipids in obese patients with recently diagnosed non-insulin-dependent diabetes
Laitinen J, Uusitupa M, Ahola I, Siitonen O. 1994. Annals of medicine. 26: 119-124 -
Metabolic evolution of type 2 diabetes: a 10-year follow-up from the time of diagnosis
Niskanen L, Karjalainen J, Siitonen O, Uusitupa M. 1994. Journal of internal medicine. 236: 263-270 -
Relation of habitual diet and cardiorespiratory fitness to blood coagulation and fibrinolytic factors
Rankinen T, Rauramaa R, Väisänen S, Penttilä IM, Uusitupa M. 1994. Thrombosis and haemostasis. 71: 180-183 -
Screening for mutations in the exon 26 of the apolipoprotein B gene in hypercholesterolemic Finnish families by the single-strand conformation polymorphism method
Ilmonen M, Heliö T, Ebeling T, Pyörälä K, Uusitupa M, Palotie A, Tikkanen MJ. 1994. Human mutation. 4: 217-223 -
Stability and magnitude of serum low-density lipoprotein response to a 6-month dietary intervention
Sarkkinen ES, Uusitupa M. 1994. Nutrition metabolism and cardiovascular diseases. 4: 36-42 -
Tehostettu ruokavalio-ohjaus voi motivoida parempaan hoitotulokseen
Uusitupa M. 1994. DIABETES (LÄÄKÄRILIITE, SYYSKUU). 46: 17-25 -
Therapeutic traditions in type 2 diabetes - are they changing?
Niskanen L, Enlund H, Jormanainen V, Nissinen A, Uusitupa M. 1994. European journal of clinical pharmacology. 46: 101-105 -
Veren suurentunut glukoosipitoisuus lisää aikuistyypin diabeetikon valtimotautiriskiä
Uusitupa M, Niskanen L. 1994. Duodecim -
Cardiac arrhythmias in the differential diagnosis of epilepsy
Nousiainen U, Mervaala E, Ylinen A, Uusitupa M, Riekkinen P. 1989. Journal of neurology. 236: 93-96