Miia Kivipelto

27‐hydroxycholesterol promotes oligodendrocyte maturation: Implications for hypercholesterolemia‐associated brain white matter changes

Alanko, Vilma; Gaminde‐Blasco, Adhara; Quintela‐López, Tania; Loera‐Valencia, Raúl; Solomon, Alina; Björkhem, Ingemar; Cedazo‐Minguez, Angel; Maioli, Silvia; Tabacaru, Graziella; Latorre‐Leal, María; Matute, Carlos; Kivipelto, Miia; Alberdi, Elena; Sandebring‐Matton, Anna. 2023. Glia. 71: 1414-1428

Age-related differences in the functional topography of the locus coeruleus and their implications for cognitive and affective functions

Veréb, Dániel; Mijalkov, Mite; Canal-Garcia, Anna; Chang, Yu-Wei; Gomez-Ruiz, Emiliano; Gerboles, Blanca Zufiria; Kivipelto, Miia; Svenningsson, Per; Zetterberg, Henrik; Volpe, Giovanni; Betts, Matthew; Jacobs, Heidi IL; Pereira, Joana B. 2023. eLife. 12: . RP87188

Association of Sarcopenia and Its Defining Components with the Degree of Cognitive Impairment in a Memory Clinic Population

Larsson, Liss Elin; Wang, Rui; Cederholm, Tommy; Wiggenraad, Fleur; Rydén, Marie; Hagman, Göran; Hellénius, Mai-Lis; Kivipelto, Miia; Thunborg, Charlotta. 2023. Journal of Alzheimer's disease. 96: 777-788

Combined Evidence for a Long-Term, Clinical Slowing Effect of Multinutrient Intervention in Prodromal Alzheimer’s Disease: Post-Hoc Analysis of 3-Year Data from the LipiDiDiet Trial

Hendrix, Suzanne B; Soininen, H; Solomon, A; Visser, PJ; van Hees, AMJ; Counotte, DS; Nicodemus-Johnson, J; Dickson, SP; Blennow, K; Kivipelto, M; Hartmann, T; LipiDiDiet clinical study group. 2023. The Journal of prevention of Alzheimer's disease. 10: 464-470

Communication about diagnosis, prognosis, and prevention in the memory clinic: perspectives of European memory clinic professionals

Hendriksen, Heleen MA; van Gils, Aniek M; van Harten, Argonde C; Hartmann, Tobias; Mangialasche, Francesca; Kamondi, Anita; Kivipelto, Miia; Rhodius-Meester, Hanneke FM; Smets, Ellen MA; van der Flier, Wiesje M; Visser, Leonie NC. 2023. Alzheimer's research and therapy. 15: . 131

Dementia prevention in memory clinics: recommendations from the European task force for brain health services

Frisoni, Giovanni B.; Altomare, Daniele; Ribaldi, Federica; Villain, Nicolas; Brayne, Carol; Mukadam, Naaheed; Abramowicz, Marc; Barkhof, Frederik; Berthier, Marcelo; Bieler-Aeschlimann, Melanie; Blennow, Kaj; Brioschi Guevara, Andrea; Carrera, Emmanuel; Chételat, Gaël; Csajka, Chantal; Demonet, Jean-François; Dodich, Alessandra; Garibotto, Valentina; Georges, Jean; Hurst, Samia; Jessen, Frank; Kivipelto, Miia; Llewellyn, David J.; McWhirter, Laura; Milne, Richard; Minguillón, Carolina; Miniussi. 2023. The Lancet regional health – Europe. 26:

Latin American Initiative for Lifestyle Intervention to Prevent Cognitive Decline (LatAm‐FINGERS): Study design and harmonization

Crivelli, Lucia; Calandri, Ismael Luis; Suemoto, Claudia Kimie; Salinas, Rosa María; Velilla, Lina Marcela; Yassuda, Mônica Sanches; Caramelli, Paulo; Lopera, Francisco; Nitrini, Ricardo; Sevlever, Gustavo Emilio; Sosa, Ana Luisa; Acosta, Daisy; Baietti, Ana María Charamelo; Cusicanqui, María Isabel; Custodio, Nilton; De Simone, Sergio Dansilio; Derio, Carolina Delgado; Duque‐Peñailillo, Lissette; Duran, Juan Carlos; Jiménez‐Velázquez, Ivonne Z.; Leon‐Salas, Jorge Mario; Bergamo, Yanina; Clarens. 2023. Alzheimer's & dementia. 19: 4046-4060

Longitudinal study of Alzheimer's disease biomarkers, allostatic load, and cognition among memory clinic patients

Adedeji, Dickson O.; Holleman, Jasper; Juster, Robert-Paul; Udeh-Momoh, Chinedu T.; Kåreholt, Ingemar; Hagman, Göran; Aspö, Malin; Adagunodo, Sofia; Håkansson, Krister; Kivipelto, Miia; Solomon, Alina; Sindi, Shireen. 2023. Brain, behavior, & immunity : health. 28:

Markers of vitamin B12 status in relation to cerebrospinal fluid biomarkers of Alzheimer's disease and cognitive performance

Hooshmand, Babak; Appold, Franziska; Fissler, Patrick; Perneczky, Robert; Otto, Markus; Tumani, Hayrettin; Kivipelto, Miia; von Arnim, Christine AF. 2023. Annals of neurology. 94: 223-231

Multimodal Precision Prevention - A New Direction in Alzheimer’s Disease

Barbera, M; Perera, D; Matton, A; Mangialasche, F; Rosenberg, A; Middleton, L; Ngandu, T; Solomon, A; Kivipelto, Miia. 2023. The Journal of prevention of Alzheimer's disease. 10: 718-728

Precision medicine in neurodegeneration: the IHI-PROMINENT project

Tate, Ashley; Suárez-Calvet, Marc; Ekelund, Mats; Eriksson, Sven; Eriksdotter, Maria; Van Der Flier, Wiesje M.; Georges, Jean; Kivipelto, Miia; Kramberger, Milica G.; Lindgren, Peter; López, Juan Domingo Gispert; Lötjönen, Jyrki; Persson, Sofie; Pla, Sandra; Solomon, Alina; Thurfjell, Lennart; Wimo, Anders; Winblad, Bengt; Jönsson, Linus; PROMINENT consortium. 2023. Frontiers in neurology. 14: . 1175922

Protective Alzheimer's disease-associated APP A673T variant predominantly decreases sAPPβ levels in cerebrospinal fluid and 2D/3D cell culture models

Wittrahm, Rebekka; Takalo, Mari; Kuulasmaa, Teemu; Mäkinen, Petra M; Mäkinen, Petri; Končarević, Saša; Fartzdinov, Vadim; Selzer, Stefan; Kokkola, Tarja; Antikainen, Leila; Martiskainen, Henna; Kemppainen, Susanna; Marttinen, Mikael; Jeskanen, Heli; Rostalski, Hannah; Rahunen, Eija; Kivipelto, Miia; Ngandu, Tiia; Natunen, Teemu; Lambert, Jean-Charles; Tanzi, Rudolph E; Kim, Doo Yeon; Rauramaa, Tuomas; Herukka, Sanna-Kaisa; Soininen, Hilkka; Laakso, Markku; Pike, Ian; Leinonen, Ville; Haapasalo, . 2023. Neurobiology of disease. 182:

Recruitment of pre-dementia participants: main enrollment barriers in a longitudinal amyloid-PET study

Bader, Ilse; Bader, Ilona; Lopes Alves, Isadora; Vallez Garcia, David; Vellas, Bruno; Dubois, Bruno; Boada, Merce; Marquie, Marta; Altomare, Daniele; Scheltens, Philip; Vandenberghe, Rik; Hanseeuw, Bernard; Scholl, Michael; Frisoni, Giovanni B; Jessen, Frank; Nordberg, Agneta; Kivipelto, Miia; Ritchie, Craig W; Grau-Rivera, Oriol; Molinuevo, Jose Luis; Ford, Lisa; Stephens, Andrew; Gismondi, Rossella; Gispert, Juan Domingo; Farrar, Gill; Barkhof, Frederik; Visser, Pieter Jelle; Collij, Lyduine E. 2023. Alzheimer's research and therapy. 15:

Response to “Comment on ‘Dementia prevention: The potential long-term cost-effectiveness of the FINGER prevention program’”

Wimo, Anders; Handels, Ron; Antikainen, Riitta; Eriksdotter, Maria; Jönsson, Linus; Knapp, Martin; Kulmala, Jenni; Laatikainen, Tiina; Lehtisalo, Jenni; Peltonen, Markku; Sköldunger, Anders; Soininen, Hilkka; Solomon, Alina; Timo Strandberg, T; Tuomilehto, Jaakko; Ngandu, Tiia; Kivipelto, Miia. 2023. Alzheimer's & dementia. 19: 4760-4763

Study design and methods: US study to protect brain health through lifestyle intervention to reduce risk (US POINTER)

Baker, Laura D; Snyder, Heather M; Espeland, Mark A; Whitmer, Rachel A; Kivipelto, Miia; Woolard, Nancy; Katula, Jeffrey; Papp, Kathryn V.; Ventrelle, Jennifer; Graef, Sarah; Hill, Marcus A; Rushing, Scott; Spell, Julia; Lovato, Laura; Felton, Deborah; Williams, Benjamin J; Ghadimi Nouran, Mina; Raman, Rema; Ngandu, Tiia; Solomon, Alina; Wilmoth, Sharon; Cleveland, Maryjo L; Williamson, Jeff D.; Lambert, Katherine L; Tomaszewski Farias, Sarah; Day, Claire E; Tangney, Christy C; Gitelman, Darren . 2023. Alzheimer's & dementia. [Epub ahead of print 30 Sep 2023]: 1-14

Aivoterveyden edistäminen perusterveydenhuollossa vaatii vielä vahvistusta

Plaami, Ella; Lampio, Terhi; Pulkkinen, Pia; Hammar, Teija; Ngandu, Tiia; Roitto, Hanna-Maria; Kivipelto, Miia; Kulmala, Jenni. 2022. Gerontologia. 36: 420-425

Antioxidants and Dementia

Hooshmand, Babak; Kivipelto, Miia. 2022. Neurology. 98: 871-872

Association Between Cognition, Health Related Quality of Life, and Costs in a Population at Risk for Cognitive Decline

Janssen, Niels; Handels, Ron L.; Wimo, Anders; Antikainen, Riitta; Laatikainen, Tiina; Soininen, Hilkka; Strandberg, Timo; Tuomilehto, Jaakko; Kivipelto, Miia; Evers, Silvia M.A.A.; Verhey, Frans R.J.; Ngandu, Tiia. 2022. Journal of Alzheimer's disease. 89: 623-632

Associations of Depressive Symptoms and Cognition in the FINGER Trial: A Secondary Analysis of a Randomised Clinical Trial

Neuvonen, Elisa; Lehtisalo, Jenni; Ngandu, Tiia; Levälahti, Esko; Antikainen, Riitta; Hänninen, Tuomo; Laatikainen, Tiina; Lindström, Jaana; Paajanen, Teemu; Soininen, Hilkka; Strandberg, Timo; Tuomilehto, Jaakko; Kivipelto, Miia; Solomon, Alina. 2022. Journal of clinical medicine. 11:

COVID-19 pandemic and mortality in nursing homes across USA and Europe up to October 2021

Aalto, Ulla L.; Pitkälä, Kaisu H.; Andersen-Ranberg, Karen; Bonin-Guillaume, Sylvie; Cruz-Jentoft, Alfonso Jose; Eriksdotter, Maria; Gordon, Adam L.; Gosch, Markus; Holmerova, Iva; Kautiainen, Hannu; Kivipelto, Miia; Macijauskiene, Jurate; O’Neill, Desmond; van den Noortgate, Nele; Ranhoff, Anette H.; Schols, Jos M. G. A.; Singler, Katrin; Stankunas, Mindaugas; Ouslander, Joseph G.. 2022. European geriatric medicine. 13: 705-709

Can dementia risk be reduced by following the American Heart Association's Life's Simple 7? A systematic review and dose-response meta-analysis

Wu, Jing; Xiong, Ying; Xia, Xin; Orsini, Nicola; Qiu, Chengxuan; Kivipelto, Miia; Rizzuto, Debora; Wang, Rui. 2022. Ageing research reviews. 2023; 83:

Can exercise training teach us how to treat Alzheimer’s disease?

Huuha, Aleksi M; Norevik, Cecilie S.; Moreira, José Bianco N; Kobro-Flatmoen, Asgeir; Scrimgeour, Nathan; Kivipelto, Miia; Van Praag, Henriette; Ziaei, Maryam; Sando, Sigrid Botne; Wisløff, Ulrik; Tari, Atefe R. 2022. Ageing research reviews. 75:

Changes in Brain-Health Related Modifiable Risk Factors in Older Adults After One Year of COVID-19-Restrictions

Waterink, Lisa; Bakker, Els D.; Visser, Leonie N. C.; Mangialasche, Francesca; Kivipelto, Miia; Deckers, Kay; Köhler, Sebastian; Sikkes, Sietske A. M.; Prins, Niels D.; Scheltens, Philip; Flier, Wiesje M. van der; Zwan, Marissa D.. 2022. Frontiers in psychiatry. 13:

Changes in cognitive functioning after COVID‐19: A systematic review and meta‐analysis

Crivelli, Lucia; Palmer, Katie; Calandri, Ismael; Guekht, Alla; Beghi, Ettore; Carroll, William; Frontera, Jennifer; García‐Azorín, David; Westenberg, Erica; Winkler, Andrea Sylvia; Mangialasche, Francesca; Allegri, Ricardo F; Kivipelto, Miia. 2022. Alzheimer's & dementia. 18: 1047-1066

Cognitive Performance at Time of AD Diagnosis: A Clinically Augmented Register-Based Study

Alenius, Minna; Hokkanen, Laura; Koskinen, Sanna; Hallikainen, Ilona; Hänninen, Tuomo; Karrasch, Mira; Raivio, Minna M.; Laakkonen, Marja-Liisa; Krüger, Johanna; Suhonen, Noora-Maria; Kivipelto, Miia; Ngandu, Tiia. 2022. Frontiers in psychology. 13: . 901945

Cortisol, cognition and Alzheimer’s disease biomarkers among memory clinic patients

Holleman, Jasper; Adagunodo, Sofia; Kåreholt, Ingemar; Hagman, Göran; Aspö, Malin; Udeh-Momoh, Chinedu T; Solomon, Alina; Kivipelto, Miia; Sindi, Shireen. 2022. BMJ neurology open. 4:

Dementia Risk Scores and Their Role in the Implementation of Risk Reduction Guidelines

Anstey, Kaarin J; Zheng, Lidan; Peters, Ruth; Kootar, Scherazad; Barbera, Mariagnese; Stephen, Ruth; Dua, Tarun; Chowdhary, Neerja; Solomon, Alina; Kivipelto, Miia. 2022. Frontiers in neurology. 12: . 765454

Dementia prevention: The potential long-term cost-effectiveness of the FINGER prevention program

Wimo, Anders; Handels, Ron; Antikainen, Riitta; Eriksdotter, Maria; Jönsson, Linus; Knapp, Martin; Kulmala, Jenni; Laatikainen, Tiina; Lehtisalo, Jenni; Peltonen, Markku; Sköldunger, Anders; Soininen, Hilkka; Solomon, Alina; Strandberg, Timo; Tuomilehto, Jaakko; Ngandu, Tiia; Kivipelto, Miia. 2022. Alzheimer's & dementia. [First published: 16 July 2022]: 1-10

Education-Based Cutoffs for Cognitive Screening of Alzheimer’s Disease

Alenius, Minna; Ngandu, Tiia; Koskinen, Sanna; Hallikainen, Ilona; Hänninen, Tuomo; Karrasch, Mira; Kivipelto, Miia; Raivio, Minna M.; Laakkonen, Marja-Liisa; Krüger, Johanna; Suhonen, Noora-Maria; Hokkanen, Laura. 2022. Dementia and geriatric cognitive disorders. 51: 42-55

Effects of Physical and Cognitive Training on Falls and Concern About Falling in Older Adults: Results From a Randomized Controlled Trial

Turunen, Katri M.; Tirkkonen, Anna; Savikangas, Tiina; Hanninen, Tuomo; Alen, Markku; Fielding, Roger A.; Kivipelto, Miia; Neely, Anna Stigsdotter; Tormakangas, Timo; Sipila, Sarianna. 2022. Journals of gerontology series a: biological sciences and medical sciences. 77: 1430-1437

Experiences of Active Everyday Life Among Persons with Prodromal Alzheimer’s Disease: A Qualitative Study

Fallahpour, Mandana; Fritz, Heather; Thunborg, Charlotta; Akenine, Ulrika; Kivipelto, Miia. 2022. Journal of multidisciplinary healthcare. 15: 1921-1932

Experiences of Participation in a Multimodal Preventive Trial MIND-AD MINI Among Persons with Prodromal Alzheimer’s Disease: A Qualitative Study

Akenine, Ulrika; Thunborg, Charlotta; Kivipelto, Miia; Fallahpour, Mandana. 2022. Journal of multidisciplinary healthcare. 15: 219-234

Factors Predicting Engagement of Older Adults With a Coach-Supported eHealth Intervention Promoting Lifestyle Change and Associations Between Engagement and Changes in Cardiovascular and Dementia Risk: Secondary Analysis of an 18-Month Multinational Randomized Controlled Trial

Coley, Nicola; Andre, Laurine; Hoevenaar-Blom, Marieke P; Ngandu, Tiia; Beishuizen, Cathrien; Barbera, Mariagnese; van Wanrooij, Lennard; Kivipelto, Miia; Soininen, Hilkka; van Gool, Willem; Brayne, Carol; Moll van Charante, Eric; Richard, Edo; Andrieu, Sandrine; HATICE study group; PRODEMOS study group. 2022. Journal of medical internet research. 24:

Liikkumisen kannustimet muistisairauksien riskiryhmään kuuluvilla ikääntyneillä

Anttila, Pia; Ngandu, Tiia; Häkkinen, Arja; Lehtisalo, Jenni; Kivipelto, Miia; Kulmala, Jenni. 2022. Gerontologia. 36: 4-15

Mechanisms Underlying Non-Pharmacological Dementia Prevention Strategies: A Translational Perspective

Alanko, V; Udeh-Momoh, C; Kivipelto, M; Sandebring-Matton, A. 2022. The Journal of prevention of Alzheimer's disease. 9: 3-11

Memory clinic clinicians’ preferences and needs for communication with patients: A multi-national survey study from EU-FINGERS & LETHE projects

Hendriksen, Heleen MA; van Gils, Aniek M; Kivipelto, Miia; Mangialasche, Francesca; Meester, Hanneke FM Rhodius; Smets, Ellen MA; van der Flier, Wiesje M; Visser, Leonie NC. 2022. Alzheimer's & dementia

Metabolome-wide association study on ABCA7 indicates a role of ceramide metabolism in Alzheimer’s disease

Dehghan, Abbas; Pinto, Rui Climaco; Karaman, Ibrahim; Huang, Jian; Durainayagam, Brenan R.; Ghanbari, Mohsen; Nazeer, Areesha; Zhong, Qi; Liggi, Sonia; Whiley, Luke; Mustafa, Rima; Kivipelto, Miia; Solomon, Alina; Ngandu, Tiia; Kanekiyo, Takahisa; Aikawa, Tomonori; Radulescu, Carola I.; Barnes, Samuel J.; Graça, Gonçalo; Chekmeneva, Elena; Camuzeaux, Stephane; Lewis, Matthew R.; Kaluarachchi, Manuja R.; Ikram, M. Arfan; Holmes, Elaine; Tzoulaki, Ioanna; Matthews, Paul M.; Griffin, Julian L.; Ell. 2022. Proceedings of the National Academy of Sciences of the United States of America. 119: . e2206083119

Multidomain interventions for risk reduction and prevention of cognitive decline and dementia: current developments

Röhr, Susanne; Kivipelto, Miia; Mangialasche, Francesca; Ngandu, Tiia; Riedel-Heller, Steffi G. 2022. Current opinion in psychiatry. 35: 285-292

Multimodal Preventive Trial for Alzheimer’s Disease: MIND-ADmini Pilot Trial Study Design and Progress

Sindi, S; Thunborg, C; Rosenberg, A; Andersen, P; Andrieu, S; Broersen, LM; Coley, N; Couderc, C; Duval, CZ; Faxen-Irving, G; Hagman, G; Hallikainen, M; Håkansson, K; Lehtisalo, J; Levak, N; Mangialasche, F; Pantel, J; Kekkonen, E; Rydström, A; Stigsdotter-Neely, A; Wimo, A; Ngandu, T; Soininen, H; Hartmann, T; Solomon, A; Kivipelto, M. 2022. The Journal of prevention of Alzheimer's disease. 9: 30-39

New insights into the genetic etiology of Alzheimer’s disease and related dementias

Bellenguez, Céline; Küçükali, Fahri; Jansen, Iris E.; Kleineidam, Luca; Moreno-Grau, Sonia; Amin, Najaf; Naj, Adam C.; Campos-Martin, Rafael; Grenier-Boley, Benjamin; Andrade, Victor; Holmans, Peter A.; Boland, Anne; Damotte, Vincent; van der Lee, Sven J.; Costa, Marcos R.; Kuulasmaa, Teemu; Yang, Qiong; de Rojas, Itziar; Bis, Joshua C.; Yaqub, Amber; Prokic, Ivana; Chapuis, Julien; Ahmad, Shahzad; Giedraitis, Vilmantas; Aarsland, Dag; Garcia-Gonzalez, Pablo; Abdelnour, Carla; Alarcón-Martín, Em. 2022. Nature genetics. 54: 412-436

Occupational complexity and cognition in the FINGER multidomain intervention trial

Rydström, Anders; Darin‐Mattsson, Alexander; Kåreholt, Ingemar; Ngandu, Tiia; Lehtisalo, Jenni; Solomon, Alina; Antikainen, Riitta; Bäckman, Lars; Hänninen, Tuomo; Laatikainen, Tiina; Levälahti, Esko; Lindström, Jaana; Paajanen, Teemu; Havulinna, Satu; Peltonen, Markku; Sindi, Shireen; Soininen, Hilkka; Neely, Anna Stigsdotter; Strandberg, Timo; Tuomilehto, Jaakko; Kivipelto, Miia; Mangialasche, Francesca. 2022. Alzheimer's & dementia. 18: 2438-2447

Psychosocial determinants for adherence to a healthy lifestyle and intervention participation in the FINGER trial: an exploratory analysis of a randomised clinical trial

Neuvonen, Elisa; Lehtisalo, Jenni; Solomon, Alina; Antikainen, Riitta; Havulinna, Satu; Hänninen, Tuomo; Laatikainen, Tiina; Lindström, Jaana; Rautio, Nina; Soininen, Hilkka; Strandberg, Timo; Tuomilehto, Jaakko; Kivipelto, Miia; Ngandu, Tiia. 2022. Aging clinical and experimental research. 34: 1793-1805

Reducing the Risk of Cognitive Decline and Dementia: WHO Recommendations

Chowdhary, Neerja; Barbui, Corrado; Anstey, Kaarin J.; Kivipelto, Miia; Barbera, Mariagnese; Peters, Ruth; Zheng, Lidan; Kulmala, Jenni; Stephen, Ruth; Ferri, Cleusa P.; Joanette, Yves; Wang, Huali; Comas-Herrera, Adelina; Alessi, Charles; Suharya (Dy), Kusumadewi; Mwangi, Kibachio J.; Petersen, Ronald C.; Motala, Ayesha A.; Mendis, Shanthi; Prabhakaran, Dorairaj; Bibi Mia Sorefan, Ameenah; Dias, Amit; Gouider, Riadh; Shahar, Suzana; Ashby-Mitchell, Kimberly; Prince, Martin; Dua, Tarun. 2022. Frontiers in neurology. 12: . 765584

Serum Thioredoxin-80 is associated with age, ApoE4, and neuropathological biomarkers in Alzheimer’s disease: a potential early sign of AD

Goikolea, Julen; Gerenu, Gorka; Daniilidou, Makrina; Mangialasche, Francesca; Mecocci, Patrizia; Ngandu, Tiia; Rinne, Juha; Solomon, Alina; Kivipelto, Miia; Cedazo-Minguez, Angel; Sandebring-Matton, Anna; Maioli, Silvia. 2022. Alzheimer's research and therapy. 14: . 37

Trajectories of cognitive decline and dementia development: A 12‐year longitudinal study

Payton, Nicola M; Marseglia, Anna; Grande, Giulia; Fratiglioni, Laura; Kivipelto, Miia; Bäckman, Lars; Laukka, Erika J. 2022. Alzheimer's & dementia. [First published: 17 June 2022]: 1-11

Trials and Treatments for Vascular Brain Health: Risk Factor Modification and Cognitive Outcomes

Kivipelto, Miia; Palmer, Katie; Hoang, Tina D; Yaffe, Kristine. 2022. Stroke. 53: 444-456

β-Amyloid, Tau, Neurodegeneration Classification and Eligibility for Anti-amyloid Treatment in a Memory Clinic Population

Rosenberg, Anna; Öhlund-Wistbacka, Ulf; Hall, Anette; Bonnard, Alexandre; Hagman, Göran; Rydén, Marie; Thunborg, Charlotta; Wiggenraad, Fleur; Sandebring-Matton, Anna; Solomon, Alina; Kivipelto, Miia. 2022. Neurology. 99: 1-35

27-Hydroxycholesterol, cognition, and brain imaging markers in the FINGER randomized controlled trial

Sandebring-Matton, Anna; Goikolea, Julen; Björkhem, Ingemar; Paternain, Laura; Kemppainen, Nina; Laatikainen, Tiina; Ngandu, Tiia; Rinne, Juha; Soininen, Hilkka; Cedazo-Minguez, Angel; Solomon, Alina; Kivipelto, Miia. 2021. Alzheimer's research and therapy. 13: 56

A competing risk joint model for dealing with different types of missing data in an intervention trial in prodromal Alzheimer's disease

Swinkels, Sophie HN; Soininen, Hilkka; Kivipelto, Miia; Hartmann, Tobias; Rizopoulos, Dimitris. 2021. Alzheimer's research and therapy. 13: 63

Alzheimer's disease

Scheltens, Philip; De Strooper, Bart; Kivipelto, Miia; Holstege, Henne; Chételat, Gael; Teunissen, Charlotte E; Cummings, Jeffrey; van der Flier, Wiesje M. 2021. The Lancet. 397: 1577-1590

Blood Derived Amyloid Biomarkers for Alzheimer's Disease Prevention

Udeh-Momoh, C; Zheng, B; Sandebring-Matton, A; Novak, G; Kivipelto, M; Jönsson, L; Middleton, L; Alzheimer's Disease Neuroimaging Initiative. 2021. The Journal of prevention of Alzheimer's disease. 2022; 9: 12-21

Change in CAIDE Dementia Risk Score and neuroimaging biomarkers during a 2-year multidomain lifestyle randomized controlled trial: results of a post-hoc subgroup analysis

Stephen, Ruth; Ngandu, Tiia; Liu, Yawu; Peltonen, Markku; Antikainen, Riitta; Kemppainen, Nina; Laatikainen, Tiina; Lötjönen, Jyrki; Rinne, Juha; Strandberg, Timo; Tuomilehto, Jaakko; Vanninen, Ritva; Soininen, Hilkka; Kivipelto, Miia; Solomon, Alina. 2021. Journals of gerontology series a: biological sciences and medical sciences. 76: 1407-1414

Changes in Lifestyle, Behaviors, and Risk Factors for Cognitive Impairment in Older Persons During the First Wave of the Coronavirus Disease 2019 Pandemic in Finland: Results From the FINGER Study

Lehtisalo, Jenni; Palmer, Katie; Mangialasche, Francesca; Solomon, Alina; Kivipelto, Miia; Ngandu, Tiia. 2021. Frontiers in psychiatry. 12: 624125

Common variants in Alzheimer's disease and risk stratification by polygenic risk scores

de Rojas, I; Moreno-Grau, S; Tesi, N; Grenier-Boley, B; Andrade, V; Jansen, IE; Pedersen, NL; Stringa, N; Zettergren, A; Hernández, I; Montrreal, L; Antúnez, C; Antonell, A; Tankard, RM; Bis, JC; Sims, R; Bellenguez, C; Quintela, I; González-Perez, A; Calero, M; et al; [incl. Haapasalo, A; Soininen, H; Lehtisalo, J; Kivipelto, M; Kuulasmaa, T; Hiltunen, M]. 2021. Nature communications. 12: 3417

Dementia research in 2020: moving forward despite the COVID-19 pandemic

Kivipelto, Miia; Mangialasche, Francesc. 2021. The Lancet Neurology. 20: 3-5

Development of the First WHO Guidelines for Risk Reduction of Cognitive Decline and Dementia: Lessons Learned and Future Directions

Stephen, Ruth; Barbera, Mariagnese; Peters, Ruth; Ee, Nicole; Zheng, Lidan; Lehtisalo, Jenni; Kulmala, Jenni; Håkansson, Krister; Chowdhary, Neerja; Dua, Tarun; Solomon, Alina; Anstey, Kaarin J; Kivipelto, Miia. 2021. Frontiers in neurology. 12: 763573

Digital Screening for Cognitive Impairment - A Proof of Concept Study

Bloniecki, Victor; Hagman, G; Ryden, M; Kivipelto, M. 2021. The Journal of prevention of Alzheimer's disease. 8: 127-134

Editorial: Cognitive, Psychological, and Psychiatric Consequences of the Coronavirus (COVID-19) Pandemic in the Population of Older Persons With Cognitive Impairment, Dementia, and/or Neuropsychiatric Disorders

Palmer, Katie; Kivipelto, Miia; Gianni, Walter; Banaj, Nerisa; Spalletta, Gianfranco. 2021. Frontiers in psychiatry. 12: 748963

Effect of a Multidomain Lifestyle Intervention on Estimated Dementia Risk

Solomon, Alina; Handels, Ron; Wimo, Anders; Antikainen, Riitta; Laatikainen, Tiina; Levälahti, Esko; Peltonen, Markku; Soininen, Hilkka; Strandberg, Timo; Tuomilehto, Jaakko; Kivipelto, Miia; Ngandu, Tiia. 2021. Journal of Alzheimer's disease. 82: 1461-1466

Effects of physical and cognitive training on gait speed and cognition in older adults: A randomized controlled trial

Sipilä, Sarianna; Tirkkonen, Anna; Savikangas, Tiina; Hänninen, Tuomo; Laukkanen, Pia; Alen, Markku; Fielding, Roger A; Kivipelto, Miia; Kulmala, Jenni; Rantanen, Taina; Sihvonen, Sanna E; Sillanpää, Elina; Stigsdotter Neely, Anna; Törmäkangas, Timo. 2021. Scandinavian journal of medicine and science in sports. 31: 1518-1533

Exercise, diet, and cognition in a 4-year randomized controlled trial: Dose-Responses to Exercise Training (DR's EXTRA)

Komulainen, Pirjo; Tuomilehto, Jaakko; Savonen, Kai; Männikkö, Reija; Hassinen, Maija; Lakka, Timo A; Hänninen, Tuomo; Kiviniemi, Vesa; Jacobs, David R; Kivipelto, Miia; Rauramaa, Rainer. 2021. American journal of clinical nutrition. 113: 1428-1439

Facilitators and barriers to implementing lifestyle intervention programme to prevent cognitive decline

Kulmala, J; Rosenberg, A; Ngandu, T; Hemiö, K; Tenkula, T; Hyytiä, A; Vienola, M; Huhtamäki-Kuoppala, M; Saarinen, A; Korkki, S; Laatikainen, T; Solomon, A; Kivipelto, M. 2021. European journal of public health. 31: 816-822

Health, Lifestyle, and Psycho-Social Determinants of Poor Sleep Quality During the Early Phase of the COVID-19 Pandemic: A Focus on UK Older Adults Deemed Clinically Extremely Vulnerable

Udeh-Momoh, Chinedu T.; Watermeyer, Tamlyn; Sindi, Shireen; Giannakopoulou, Parthenia; Robb, Catherine E.; Ahmadi-Abhari, Sara; Zheng, Bang; Waheed, Amina; McKeand, James; Salman, David; Beaney, Thomas; de Jager Loots, Celeste A.; Price, Geraint; Atchison, Christina; Car, Josip; Majeed, Azeem; McGregor, Alison. H.; Kivipelto, Miia; Ward, Helen; Middleton, Lefkos T.. 2021. Frontiers in public health. 9: 753964

How can dementia and disability be prevented in older adults: Where are we today and where are we going?

Lisko, Inna; Kulmala, Jenni; Annetorp, Martin; Ngandu, Tiia; Mangialasche, Francesca; Kivipelto, Miia. 2021. Journal of internal medicine. 289: 807-830

Impact of the COVID-19 pandemic on statistical design and analysis plans for multidomain intervention clinical trials: Experience from World-Wide FINGERS

Röhr, Susanne; Arai, Hidenori; Mangialasche, Francesca; Matsumoto, Nanae; Peltonen, Markku; Raman, Rema; Riedel-Heller, Steffi G.; Sakurai, Takashi; Snyder, Heather M.; Sugimoto, Taiki; Carrillo, Maria; Kivipelto, Miia; Espeland, Mark A. 2021. Alzheimer's & dementia : Translational research & clinical interventions. 7: e12143

Muistisairaudet

Lehtisalo, Jenni; Kivipelto, Miia; Ngandu, Tiia; Eskelinen, Marjo; Soininen, Hilkka. Teoksessa: Mutanen, Marja; Niinikoski, Harri; Schwab, Ursula; Uusitupa, Matti(toim.) , 2021. Ravitsemustiede (8. uud. painos). s. 461-466. Duodecim

Multidomain interventions: state-of-the-art and future directions for protocols to implement precision dementia risk reduction. A user manual for Brain Health Services-part 4 of 6

Solomon, Alina; Stephen, Ruth; Altomare, Daniele; Carrera, Emmanuel; Frisoni, Giovanni B.; Kulmala, Jenni; Molinuevo, José Luis; Nilsson, Peter; Ngandu, Tiia; Ribaldi, Federica; Vellas, Bruno; Scheltens, Philip; Kivipelto, Miia; European Task Force for Brain Health Services. 2021. Alzheimer's research and therapy. 13: 171

Personal Social Networks of Community-Dwelling Oldest Old During the Covid-19 Pandemic - A Qualitative Study

Kulmala, Jenni; Tiilikainen, Elisa; Lisko, Inna; Ngandu, Tiia; Kivipelto, Miia; Solomon, Alina. 2021. Frontiers in public health. 9: 770965

Quantifying dementia prevention potential in the FINGER randomized controlled trial using the LIBRA prevention index.

Deckers, Kay; Köhler, Sebastian; Ngandu, Tiia; Antikainen, Riitta; Laatikainen, Tiina; Soininen, Hilkka; Strandberg, Timo; Verhey, Frans; Kivipelto, Miia; Solomon, Alina. 2021. Alzheimer's & dementia. 17: 1205-1212

Red Cell Distribution Width and Dementia Among Rural-Dwelling Older Adults: The MIND-China Study

Jiang, Z; Han, X; Wang, Y; Hou, T; Cong, L; Tang, S; Han, X; Ngandu, T; Kivipelto, M; Winblad, B; Launer, LJ; Du, Y; Qiu, C. 2021. Journal of Alzheimer's disease. 83: 1187-1198

Research diagnostic criteria for Alzheimer's disease: findings from the LipiDiDiet randomized controlled trial

Rosenberg, Anna; Solomon, Alina; Soininen, Hilkka; Visser, Pieter Jelle; Blennow, Kaj; Hartmann, Tobias; Kivipelto, Miia; on behalf of the LipiDiDiet clinical study group [incl. Hallikainen, Ilona; Hallikainen, Merja; Helisalmi, Seppo; Lappalainen, Tarja; Liu, Yawu; Paajanen, Teemu]. 2021. Alzheimer's research and therapy. 13: 64

Serum proBDNF Is Associated With Changes in the Ketone Body ß-Hydroxybutyrate and Shows Superior Repeatability Over Mature BDNF: Secondary Outcomes From a Cross-Over Trial in Healthy Older Adults

Norgren, Jakob; Daniilidou, Makrina; Kåreholt, Ingemar; Sindi, Shireen; Akenine, Ulrika; Nordin, Karin; Rosenborg, Staffan; Ngandu, Tiia; Kivipelto, Miia; Sandebring-Matton, Anna. 2021. Frontiers in aging neuroscience. 13: 716594

Sex and gender differences in genetic and lifestyle risk and protective factors for dementia

Sindi, Shireen; Toopchiani, Sima; Barbera, Mariagnese; Håkansson, Krister; Lehtisalo, Jenni; Rosenberg, Anna; Stephen, Ruth; Udeh-Momoh, Chinedu; Kivipelto, Miia. Teoksessa: Ferretti, Maria Teresa; Schumacher Dimech, Annemarie; Santuccione Chadha, Antonella(toim.) , 2021. Sex and Gender Differences in Alzheimer's Disease. s. 269-308. Academic press

Sex differences in dementia and response to a lifestyle intervention: Evidence from Nordic population-based studies and a prevention trial

Sindi, S; Kåreholt, I; Ngandu, T; Rosenberg, A; Kulmala, J; Johansson, L; Wetterberg, H; Skoog, J; Sjöberg, L; Wang, HX; Fratiglioni, L; Skoog, I; Kivipelto, M. 2021. Alzheimer's & dementia. 17: 1166-1178

Telomere length change in a multidomain lifestyle intervention to prevent cognitive decline: a randomized clinical trial

Sindi, Shireen; Solomon, Alina; Kåreholt, Ingemar; Hovatta, Iiris; Antikainen, Riitta; Hänninen, Tuomo; Levälahti, Esko; Laatikainen, Tiina; Lehtisalo, Jenni; Lindström, Jaana; Paajanen, Teemu; Peltonen, Markku; Singh Khalsa, Dharma; Wolozin, Benjamin; Strandberg, Timo; Tuomilehto, Jaakko; Soininen, Hilkka; Ngandu, Tiia; Kivipelto, Miia; for the FINGER Study Group. 2021. Journals of gerontology series a: biological sciences and medical sciences. 76: 491-498

The effect of adherence on cognition in a multidomain lifestyle intervention (FINGER)

Ngandu, Tiia; Lehtisalo, Jenni; Korkki, Saana; Solomon, Alina; Coley, Nicola; Antikainen, Riitta; Bäckman, Lars; Hänninen, Tuomo; Lindström, Jaana; Laatikainen, Tiina; Paajanen, Teemu; Havulinna, Satu; Peltonen, Markku; Neely, Anna Stigsdotter; Strandberg, Timo; Tuomilehto, Jaakko; Soininen, Hilkka; Kivipelto, Miia. 2021. Alzheimer's & dementia. First published: 20 October 2021: 1 - 10

The effects of a physical and cognitive training intervention vs. physical training alone on older adults' physical activity: A randomized controlled trial with extended follow-up during COVID-19

Savikangas, Tiina; Törmäkangas, Timo; Tirkkonen, Anna; Alen, Markku; Fielding, Roger A.; Kivipelto, Miia; Rantalainen, Timo; Stigsdotter Neely, Anna; Sipilä, Sarianna. 2021. PLoS ONE. 16: 1 - 20

Association of Peripheral Insulin Resistance and Other Markers of Type 2 Diabetes Mellitus With Brain Amyloid Deposition in Healthy Individuals at Risk of Dementia

Pekkala, Timo; Hall, Anette; Mangialasche, Francesca; Kemppainen, Niina; Mecocci, Patrizia; Ngandu, Tiia; Rinne, Juha O; Soininen, Hilkka; Tuomilehto, Jaakko; Kivipelto. Miia; Solomon. Alina 1 2. 2020. Journal of Alzheimer's disease. 76: 1243-1248

Attitudes of at-risk older adults about prevention of cardiovascular disease and dementia using eHealth: a qualitative study in a European context.

Akenine, Ulrika; Barbera, Mariagnese; Beishuizen, Cathrien Rl; Fallah Pour, Mandana; Guillemont, Juliette; Rosenberg, Anna; Coley, Nicola; Mangialasche, Francesca; Salo, Lotta; Savy, Stephanie; Pols, A Jeannette; Andrieu, Sandrine; Richard, Edo; Soininen, Hilkka; Moll van Charante, Eric; Kivipelto, Miia; The HATICE study group. 2020. BMJ open. 10: e037050

Capillary blood tests may overestimate ketosis: triangulation between three different measures of ß-hydroxybutyrate

Norgren, J; Sindi, S; Sandebring-Matton, A; Kåreholt, I; Akenine, U; Nordin, K;, Rosenborg, S; Ngandu, T; Kivipelto, M. 2020. American journal of physiology : endocrinology and metabolism. 318: E184-E188

Cardiovascular health metrics from mid- to late-life and risk of dementia: A population-based cohort study in Finland

Liang, Yajun; Ngandu, Tiia; Laatikainen, Tiina; Soininen, Hilkka; Tuomilehto, Jaakko; Kivipelto, Miia; Qiu, Chengxuan. 2020. PLoS medicine. 17: e1003474

Combining Cognitive Markers to Identify Individuals at Increased Dementia Risk: Influence of Modifying Factors and Time to Diagnosis

Payton, Nicola; Rizzuto, Debora; Fratiglioni, Laura; Kivipelto, Miia; Bäckman, Lars; Laukka, Erika. 2020. Journal of the international neuropsychological society. 26: 785-797

Dementia risk scores as surrogate outcomes for lifestyle-based multidomain prevention trials - rationale, preliminary evidence and challenges

Coley, N; Hoevenaar-Blom, MP; van Dalen, JW; Moll van Charante, EP; Kivipelto, M; Soininen, H; Andrieu, S; Richard, E. 2020. Alzheimer's & dementia. 16: 1674-1685

Detecting Amyloid Positivity in Elderly With Increased Risk of Cognitive Decline

Pekkala, Timo; Hall, Anette; Ngandu, Tiia; Gils, Mark van; Helisalmi, Seppo; Hänninen, Tuomo; Kemppainen, Nina; Liu, Yawu; Lötjönen, Jyrki; Paajanen, Teemu; Rinne, Juha O; Soininen, Hilkka; Kivipelto, Miia; Solomon, Alina. 2020. Frontiers in aging neuroscience. 12: 228

Earlier life leisure-time physical activity in relation to age-related frailty syndrome

Kolehmainen, L; Havulinna, S; Ngandu, T; Strandberg, T; Levälahti, E; Lehtisalo, J; Antikainen, R; Hietikko, E; Peltonen, M; Pölönen, A; Soininen, H; Tuomilehto, J; Laatikainen, T; Rauramaa, R; Kivipelto, M; Kulmala, J. 2020. Age and ageing. 2021; 50: 161-168

Effects of daily L-dopa administration on learning and brain structure in older adults undergoing cognitive training: a randomised clinical trial

Lebedev, AV; Nilsson, J; Lindström, J; Fredborg, W; Akenine, U; Hillilä, C; Andersen, P; Spulber, G; de Lange, ECM; van den Berg, D-J; Kivipelto, M; Lövdén, M. 2020. Scientific reports. 10: 5227

Evaluation of a Novel Psychological Intervention Tailored for Patients With Early Cognitive Impairment (PIPCI): Study Protocol of a Randomized Controlled Trial

Ekman, Urban; Kemani, Mike K.; Wallert, John; Wicksell, Rikard K.; Holmström, Linda; Ngandu, Tiia; Rennie, Anna; Akenine, Ulrika; Westman, Eric; Kivipelto, Miia. 2020. Frontiers in psychology. 11: 600841

Experiences of dementia and attitude towards prevention: a qualitative study among older adults participating in a prevention trial

Rosenberg, Anna; Coley, Nicola; Soulier, Alexandra; Kulmala, Jenni; Soininen, Hilkka; Andrieu, Sandrine; Kivipelto, Miia; Barbera, Mariagnese; for the MIND-AD and HATICE groups. 2020. Bmc geriatrics. 20: 99

Ketosis After Intake of Coconut Oil and Caprylic Acid-With and Without Glucose: A Cross-Over Study in Healthy Older Adults

Norgren, Jakob; Sindi, Shireen; Sandebring-Matton, Anna; Kåreholt, Ingemar; Daniilidou, Makrina; Akenine, Ulrika; Nordin, Karin; Rosenborg, Staffan; Ngandu, Tiia; Kivipelto, Miia. 2020. Frontiers in nutrition. 7: 40

Late-life personality traits, cognitive impairment, and mortality in a population-based cohort

Neuvonen, Elisa; Hall, Anette; Tolppanen, Anna-Maija; Ngandu, Tiia; Rusanen, Minna; Laatikainen, Tiina; Soininen, Hilkka; Kivipelto, Miia; Solomon, Alina. 2020. International journal of geriatric psychiatry. 35: 989-999

Pooling individual participant data from randomized controlled trials: Exploring potential loss of information

van Wanrooij, Lennard L; Hoevenaar-Blom, Marieke P; Coley, Nicola; Ngandu, Tiia; Meiller, Yannick; Guillemont, Juliette; Rosenberg, Anna; Beishuizen, Cathrien R L; Moll van Charante, Eric P; Soininen, Hilkka; Brayne, Carol; Andrieu, Sandrine; Kivipelto, Miia; Richard, Edo. 2020. PLoS ONE. 15: e0232970

Precision prevention of Alzheimer's and other dementias: Anticipating future needs in the control of risk factors and implementation of disease-modifying therapies

Frisoni, GB; Molinuevo, JL; Altomare, D; Carrera, EM; Barkhof, F; Berkhof, J; Delrieu, J; Dubois, B; Kivipelto, M; Nordberg, A; Schott, JM; van der Flier, WM; Vellas, B; Jessen, F; Scheltens, P; Ritchie, C. 2020. Alzheimer's & dementia. 16: 1457-1468

Sleep disturbances and the speed of multimorbidity development in old age: results from a longitudinal population-based study

Sindi, Shireen; Pérez, Laura Monica; Vetrano, Davide L; Triolo, Federico; Kåreholt, Ingemar; Sjöberg, Linnea; Darin-Mattsson, Alexander; Kivipelto, Miia; Inzitari, Marco; Calderón-Larrañaga, Amaia. 2020. Bmc medicine. 18: 382

Tackling challenges in care of Alzheimer's disease and other dementias amid the COVID-19 pandemic, now and in the future

Mok, VCT; Pendlebury, S; Wong, A; Alladi, S; Au, L; Bath, PM; Biessels, GJ; Chen, C; Cordonnier, C; Dichgans, M; Dominguez, J; Gorelick, PB; Kim, S; Kwok, T; Greenberg, SM; Jia, J; Kalaria, R; Kivipelto, M; Naegandran, K; Lam, LCW; et al.. 2020. Alzheimer's & dementia. 16: 1571-1581

The potential long-term impact of the COVID-19 outbreak on patients with non-communicable diseases in Europe: consequences for healthy ageing

Palmer, Katie; Monaco, Alessandro; Kivipelto, Miia; Onder, Graziano; Maggi, Stefania; Michel, Jean-Pierre; Prieto, Rita; Sykara, Georgia; Donde, Shaantanu. 2020. Aging clinical and experimental research. 32: 1189-1194

Third follow-up of the Cardiovascular Risk Factors, Aging and Dementia (CAIDE) cohort investigating determinants of cognitive, physical, and psychosocial wellbeing among the oldest old: the CAIDE85+ study protocol

Barbera, Mariagnese; Kulmala, Jenni; Lisko, Inna; Pietilä, Eija; Rosenberg, Anna; Hallikainen, Ilona; Hallikainen, Merja; Laatikainen, Tiina; Lehtisalo, Jenni; Neuvonen, Elisa; Rusanen, Minna; Soininen, Hilkka; Tuomilehto, Jaakko; Ngandu, Tiia; Solomon, Alina; Kivipelto, Miia. 2020. Bmc geriatrics. 20: 238

White Matter Changes on Diffusion Tensor Imaging in the FINGER Randomized Controlled Trial

Stephen, Ruth; Solomon, Alina; Ngandu, Tiia; Levälahti, Esko; Rinne, Juha O; Kemppainen, Nina; Parkkola, Riitta; Antikainen, Riitta; Strandberg, Timo; Kivipelto, Miia; Soininen, Hilkka; Liu, Yawu. 2020. Journal of Alzheimer's disease. 78: 75-86

World-Wide FINGERS Network: A global approach to risk reduction and prevention of dementia

Kivipelto, M; Mangialasche, F; Snyder, HM; Allegri, R; Andrieu, S; Arai, H; Baker, L; Belleville, S; Brodaty, H; Brucki, SM; Calandri, I; Caramelli, P; Chen, C; Chertkow, H; Chew, E; Choi, SH; Chowdhary, N; Crivelli, L; De La Torre, R; Du, Y; et al. [Incl. Lehtisalo, J; Rosenberg, A; Soininen, H; Solomon, A]. 2020. Alzheimer's & dementia. 16: 1078-1094

cCOG: A web-based cognitive test tool for detecting neurodegenerative disorders

Rhodius-Meester, HFM; Paajanen, T; Koikkalainen, J; Mahdiani, S; Bruun, M; Baroni, M; Lemstra, AW; Scheltens, P; Herukka, SK; Pikkarainen, M; Hall, A; Hänninen, T; Ngandu, T; Kivipelto, M; van Gils, M; Hasselbalch, SG; Mecocci, P; Remes, A; Soininen, H; van der Flier, WM; Lötjönen, J. 2020. Alzheimer's & dementia : diagnosis, assessment & disease monitoring. 12: e12083

AMYPAD Diagnostic and Patient Management Study: Rationale and design

Frisoni, GB; Barkhof, F; Altomare, D; Berkhof, J; Boccardi, M; Canzoneri, E; Collij, L; Drzezga, A; Farrar, G; Garibotto, V; Gismondi, R; Gispert, JD; Jessen, F; Kivipelto, M; Alves, IL; Molinuevo, JL; Nordberg, A; Payoux, P; Ritchie, C; Savicheva, I; et al. (incl. Kivipelto, Miia). 2019. Alzheimer's & dementia. 15: 388-399

Adherence to multidomain interventions for dementia prevention: Data from the FINGER and MAPT trials

Coley, N; Ngandu, T; Lehtisalo, J; Soininen, H; Vellas, B; Richard, E; Kivipelto, M; Andrieu, S; HATICE, FINGER, MAPT/DSA groups. 2019. Alzheimer's & dementia. 15: 729-741

Alzheimer's Disease Composite Score: A Post-Hoc Analysis Using Data from the LipiDiDiet Trial in Prodromal Alzheimer's Disease

Hendrix, Suzanne B; Soininen, H; van Hees, AMJ; Ellison, N; Visser, PJ; Solomon, A; Attali, A; Blennow, K; Kivipelto, M; Hartmann, T. 2019. The Journal of prevention of Alzheimer's disease. 6: 232-236

Are the Neuroprotective Effects of Exercise Training Systemically Mediated?

Tari, AR; Norevik, CS; Scrimgeour, NR; Kobro-Flatmoen, A; Storm-Mathisen, J; Bergersen, LH; Wrann, CD; Selbæk, G; Kivipelto, M; Moreira, JBN; Wisløff, U. 2019. Progress in cardiovascular diseases. 62: 94-101

Association of Methionine to Homocysteine Status With Brain Magnetic Resonance Imaging Measures and Risk of Dementia

Hooshmand, B; Refsum, H; Smith, AD; Kalpouzos, G; Mangialasche, F; von Arnim, CAF; Kåreholt, I; Kivipelto, M; Fratiglioni, L. 2019. JAMA psychiatry. 76: 1198-1205

Brain volumes and cortical thickness on MRI in the Finnish Geriatric Intervention Study to Prevent Cognitive Impairment and Disability (FINGER)

Stephen, R; Liu, Y; Ngandu, T; Antikainen, R; Hulkkonen, J; Koikkalainen, J; Kemppainen, N; Lötjönen, J; Levälahti, E; Parkkola, R; Pippola, P; Rinne, J; Strandberg, T; Tuomilehto, J; Vanninen, R; Kivipelto, M; Soininen, H; Solomon, A. 2019. Alzheimer's research and therapy. 11: 53

Cardiorespiratory Fitness and Cognition: Longitudinal Associations in the FINGER Study

Pentikäinen, H; Savonen, K; Ngandu, T; Solomon, A; Komulainen, P; Paajanen, T; Antikainen, R; Kivipelto, M; Soininen, H; Rauramaa, R. 2019. Journal of Alzheimer's disease. 68: 961-968

Computer-based cognitive training for older adults: Determinants of adherence

Turunen, Merita; Hokkanen, Lauta; Bäckman, Lars; Stigsdotter-Neely, Anna; Hänninen, Tuomo; Paajanen, Teemu; Soininen, Hilkka; Kivipelto, Miia; Ngandu, Tiia. 2019. PLoS ONE. 14: e0219541

Dietary changes and cognition over 2 years within a multidomain intervention trial - The Finnish Geriatric Intervention Study to Prevent Cognitive Impairment and Disability (FINGER)

Lehtisalo, J; Levälahti, E; Lindström, J; Hänninen, T; Paajanen, T; Peltonen, M; Antikainen, R; Laatikainen, T; Strandberg, T; Soininen, H; Tuomilehto, J; Kivipelto, M; Ngandu, T. 2019. Alzheimer's & dementia. 15: 410-417

European Prevention of Alzheimer's Dementia Longitudinal Cohort Study (EPAD LCS): study protocol

Solomon, A; Kivipelto, M; Molinuevo, JL; Tom, B; Ritchie, CW. 2019. BMJ open. 8: e021017

From prediction to dementia prevention

Solomon, A; Ngandu, T; Kivipelto, M. Teoksessa: Irving, Kate; Hogervorst, Eef; Oliveira, Deborah; Kivipelto, Miia(toim.) , 2019. New Developments in Dementia Prevention Research : State of the Art and Future Possibilities. s. 13-26. Routledge

Good for the heart and good for the brain?

Kivipelto, Miia; Ngandu, Tiia. 2019. The Lancet Neurology. 18: 327-328

Healthy ageing through internet counselling in the elderly (HATICE): a multinational, randomised controlled trial

Richard, Edo; van Charante, Eric P Moll; Hoevenaar-Blom, Marieke P; Coley, Nicola, Barbera, Mariagnese; van der Groep, Abraham; Meiller, Yannick; Mangialasche, Francesca; Beishuizen, Cathrien B; Jongstra, Susan; van Middelaar, Tessa; Van Wanrooij, Lennard L; Ngandu, Tiia; Guillemont, Juliette; Andrieu, Sandrine; Brayne, Carol; Kivipelto, Miia; Soininen, Hilkka; Van Gool, Willem A. 2019. The Lancet : digital health. 1: e424-e434

Integrating nurses' experiences with supporting behaviour change for cardiovascular prevention into a self-management internet platform in Finland and the Netherlands: a qualitative study

Beishuizen, CR; Akenine, U; Barbera, M; Rosenberg, A; Fallah Pour, M; Richard, E; Soininen, H; Mangialasche, F; Kivipelto, M; Pols, AJ; Moll van Charante, E. 2019. BMJ open. 9: e023480

Long-term dementia risk prediction by the LIBRA score: a 30-year follow-up of the CAIDE study

Deckers, K; Barbera, M; Köhler, S; Ngandu, T; van Boxtel, M; Rusanen, M; Laatikainen, T; Verhey, F; Soininen, H; Kivipelto, M; Solomon, A. 2019. International journal of geriatric psychiatry. 2020; 35: 195-203

Midlife improvements in financial situation are associated with a reduced dementia risk later in life: The CAIDE 30-Year Study

Sindi, S; Darin-Mattsson, A; Kåreholt, I; Kulmala, J; Ngandu, T; Laatikainen, T; Soininen, H; Kivipelto, M. 2019. International psychogeriatrics. [Published online 25 November 2019]: 1-8

Multidomain Interventions to Prevent Cognitive Impairment, Alzheimer's Disease, and Dementia: From FINGER to World-Wide FINGERS

Rosenberg, A; Mangialasche, F; Ngandu, T; Solomon, A; Kivipelto, M. 2019. The Journal of prevention of Alzheimer's disease. 2020; 7: 29-36

New Developments in Dementia Prevention Research : State of the Art and Future Possibilities

Irving, Kate; Hogervorst, Eef; Oliveira, Deborah; Kivipelto, Miia. 2019. Aging and Mental Health Research. . Routledge

Older Adults' Reasons for Participating in an eHealth Prevention Trial: A Cross-Country, Mixed-Methods Comparison

Coley, N; Rosenberg, A; van Middelaar, T; Soulier, A; Barbera, M; Guillemont, J; Steensma, J; Igier, V; Eskelinen, M; Soininen, H; Moll van Charante, E; Richard, E; Kivipelto, M; Andrieu, S. 2019. Journal of the american medical directors association. 20: 843-849.e5

Predicting Development of Alzheimer's Disease in Patients with Shunted Idiopathic Normal Pressure Hydrocephalus

Luikku, AJ; Hall, A; Nerg, O; Koivisto, AM; Hiltunen, M; Helisalmi, S; Herukka, SK; Junkkari, A; Sutela, A; Kojoukhova, M; Korhonen, V; Mattila, J; Lötjönen, J; Rummukainen, J; Alafuzoff, I; Jääskeläinen, JE; Remes, AM; Solomon, A; Kivipelto, M; Soininen, H; et al. [Incl. Rauramaa, T; Leinonen, V]. 2019. Journal of Alzheimer's disease. 71: 1233-1243

Prediction models for dementia and neuropathology in the oldest old: the Vantaa 85+ cohort study

Hall, A; Pekkala, T; Polvikoski, T; van Gils, M; Kivipelto, M; Lötjönen, J; Mattila, J; Kero, M; Myllykangas, L; Mäkelä, M; Oinas, M; Paetau, A; Soininen, H; Tanskanen, M; Solomon, A. 2019. Alzheimer's research and therapy. 11: 11

Prevention of cognitive decline in old age - varying effects of interventions in different populations

Qiu, Chengxuan; Johansson, Gunilla; Zhu, Feiqi; Kivipelto, Miia; Winblad, Bengt. 2019. Annals of translational medicine. 7: S142

Progression to dementia in memory clinic patients with mild cognitive impairment and normal ß-amyloid

Rosenberg, A; Solomon, A; Jelic, V; Hagman, G; Bogdanovic, N; Kivipelto, M. 2019. Alzheimer's research and therapy. 11: 99

Self and Informant Memory Reports in FINGER: Associations with Two-Year Cognitive Change

Vaskivuo, L; Hokkanen, L; Hänninen, T; Antikainen, R; Bäckman, L; Laatikainen, T; Paajanen, T; Stigsdotter-Neely, A; Strandberg, T; Tuomilehto, J; Soininen, H; Kivipelto, M; Ngandu, T. 2019. Journal of Alzheimer's disease. 71: 785-795

Serum insulin and cognitive performance in older adults: a longitudinal study

Hooshmand, B; Rusanen, M; Ngandu, T; Leiviskä, J; Sindi, S; von Arnim, CAF; Falkai, P; Soininen, H; Tuomilehto, J; Kivipelto, M. 2019. American journal of medicine. 132: 367-373

The Effect of Multidomain Lifestyle Intervention on Daily Functioning in Older People

Kulmala, J; Ngandu, T; Havulinna, S; Levälahti, E; Lehtisalo, J; Solomon, A; Antikainen, R; Laatikainen, T; Pippola, P; Peltonen, M; Rauramaa, R; Soininen, H; Strandberg, T; Tuomilehto, J; Kivipelto, M. 2019. Journal of the american geriatrics society. 67: 1138-1144

The MOPEAD project: Advancing patient engagement for the detection of "hidden" undiagnosed cases of Alzheimer's disease in the community

Rodríguez-Gómez, O; Rodrigo, A; Iradier, F; Santos-Santos, MA; Hundemer, H; Ciudin, A; Sannemann, L; Zwan, M; Glaysher, B; Wimo, A; Bonn, J; Johansson, G; Rodriguez, I; Alegret, M; Gove, D; Pinó, S; Trigueros, P; Kivipelto, M; Mathews, B; Ciudad, A; et al.. 2019. Alzheimer's & dementia. 15: 828-839

Associations between Prospective and Retrospective Subjective Memory Complaints and Neuropsychological Performance in Older Adults: The Finger Study

Vaskivuo, Laura; Hokkanen, Laura; Hänninen, Tuomo; Antikainen, Riita; Bäckman, Lars; Laatikainen, Tiina; Paajanen, Teemu; Stigsdotter-Neely, Anna; Strandberg, Timo; Tuomilehto, Jaakko; Soininen, Hilkka; Kivipelto, Miia; Ngandu, Tiia. 2018. Journal of the international neuropsychological society. 24: 1099-1109

Brain ß-Amyloid and Atrophy in Individuals at Increased Risk of Cognitive Decline

Martikainen, IK; Kemppainen, N; Johansson, J; Teuho, J; Helin, S; Liu, Y; Helisalmi, S; Soininen, H; Parkkola, R; Ngandu, T; Kivipelto, M; Rinne, JO. 2018. American journal of neuroradiology. 2019; 40: 80-85

CAIDE dementia risk score, Alzheimer and cerebrovascular pathology: a population-based autopsy study

Hooshmand, B; Polvikoski, T; Kivipelto, M; Tanskanen, M; Myllykangas, L; Mäkelä, M; Oinas, M; Paetau, A; Solomon, A. 2018. Journal of internal medicine. 283: 597-603

Decreased plasma C-reactive protein levels in APOE E 4 allele carriers

Martiskainen, Henna; Takalo, Mari; Solomon, Alina; Stancáková, Alena; Marttinen, Mikael; Natunen, Teemu; Haapasalo, Annakaisa; Herukka, Sanna-Kaisa; Kuusisto, Johanna; Soininen, Hilkka; Kivipelto, Miia; Laakso, Markku; Hiltunen, Mikko. 2018. Annals of clinical and translational neurology. 5: 1229-1240

Designing an Internet-Based Multidomain Intervention for the Prevention of Cardiovascular Disease and Cognitive Impairment in Older Adults: The HATICE Trial

Barbera, Mariagnese; Mangialasche, Francesca; Jongstra, Susan; Guillemont, Juliette; Ngandu, Tiia; Beishuizen, Cathrien; Coley, Nicola; Brayne, Carol; Andrieu, Sandrine; Richard, Edo; Soininen, Hilkka; Kivipelto, Miia. 2018. Journal of Alzheimer's disease. 62: 649-663

Effect of the Apolipoprotein E Genotype on Cognitive Change During a Multidomain Lifestyle Intervention: A Subgroup Analysis of a Randomized Clinical Trial

Solomon, A; Turunen, H; Ngandu, T; Peltonen, M; Levälahti, E; Helisalmi, S; Antikainen, R; Bäckman, L; Hänninen, T; Jula, A; Laatikainen, T; Lehtisalo, J; Lindström, J; Paajanen, T; Pajala, S; Stigsdotter-Neely, A; Strandberg, T; Tuomilehto, J; Soininen, H; Kivipelto, M. 2018. JAMA neurology. 75: 462-470

European Prevention of Alzheimer's Dementia Registry: Recruitment and prescreening approach for a longitudinal cohort and prevention trials

Vermunt, L; Veal, CD; ter Meulen, L; Chrysostomou, C; van der Flier, W; Frisoni, GB; Guessous, I; Kivipelto, M; Marizzoni, M; Martinez-Lage, P; Molinuevo, JL; Porteous, D; Ritchie, K; Scheltens, P; Ousset, P-J; Ritchie, CW; Luscan, G; Brookes, AJ; Visser, PJ. 2018. Alzheimer's & dementia. 14: 837-842

Healthy Dietary Changes in Midlife Are Associated with Reduced Dementia Risk Later in Life

Sindi, Shireen; Kåreholt, Ingemar; Eskelinen, Marjo; Hooshmand, Babak; Lehtisalo, Jenni; Soininen, Hilkka; Ngandu, Tiia; Kivipelto, Miia. 2018. Nutrients. 10: 1649

Lifestyle interventions to prevent cognitive impairment, dementia and Alzheimer disease

Kivipelto, Miia; Mangialasche, Francesca; Ngandu, Tiia. 2018. Nature reviews neurology. 14: 653-666

Monimuotoiset elintapainterventiot muistisairausepidemian ehkäisyssä

Ngandu, Tiia; Kivipelto, Miia. 2018. Duodecim. 134: 2547-2553

Multidomain lifestyle intervention benefits a large elderly population at risk for cognitive decline and dementia regardless of baseline characteristics: The FINGER trial

Rosenberg, A; Ngandu, T; Rusanen, M; Antikainen, R; Bäckman, L; Havulinna, S; Hänninen, T; Laatikainen, T; Lehtisalo, J; Levälahti, E; Lindström, J; Paajanen, T; Peltonen, M; Soininen, H; Stigsdotter-Neely, A; Strandberg, T; Tuomilehto, J; Solomon, A; Kivipelto, M. 2018. Alzheimer's & dementia. 14: 263-270

Prevention Matters: Time for Global Action and Effective Implementation

Kulmala, Jenni; Ngandu, Tiia; Kivipelto, Miia. 2018. Journal of Alzheimer's disease. 64: S191-S198

Promoting safe walking among older people: the effects of a physical and cognitive training intervention vs. physical training alone on mobility and falls among older community-dwelling men and women (the PASSWORD study): design and methods of a randomized controlled trial

Sipilä, S; Tirkkonen, A; Hänninen, T; Laukkanen, P; Alen, M; Fielding, RA; Kivipelto, M; Kokko, K; Kulmala, J; Rantanen, T; Sihvonen, SE; Sillanpää, E; Stigsdotter-Neely, A; Törmäkangas, T. 2018. Bmc geriatrics. 18: 215

Sleep disturbances and dementia risk: A multicenter study

Sindi, S; Kåreholt, I; Johansson, L; Skoog, J; Sjöberg, L; Wang, HX; Johansson, B; Fratiglioni, L; Soininen, H; Solomon, A; Skoog, I; Kivipelto, M. 2018. Alzheimer's & dementia. 14: 1235-1242

Sleep disturbances and later cognitive status: a multi-centre study

Sindi, S; Johansson, L; Skoog, J; Mattsson, AD; Sjöberg, L; Wang, HX; Fratiglioni, L; Kulmala, J; Soininen, H; Solomon, A; Johansson, B; Skoog, I; Kivipelto, M; Kåreholt, I. 2018. Sleep medicine. 52: 26-33

The Effect of a 2-Year Intervention Consisting of Diet, Physical Exercise, Cognitive Training, and Monitoring of Vascular Risk on Chronic Morbidity - the FINGER Randomized Controlled Trial

Marengoni, A; Rizzuto, D; Fratiglioni, L; Antikainen, R; Laatikainen, T; Lehtisalo, J; Peltonen, M; Soininen, H; Strandberg, T; Tuomilehto, J; Kivipelto, M; Ngandu, T. 2018. Journal of the american medical directors association. 19: 355-360.e1

24-month intervention with a specific multinutrient in people with prodromal Alzheimer's disease (LipiDiDiet): a randomised, double-blind, controlled trial

Soininen Hilkka, Solomon Alina, Jelle Visser Pieter, Hendrix Suzanne B, Blennow Kaj, Kivipelto Miia, Hartmann Tobias, LipiDiDiet clinical study group. 2017. The Lancet Neurology. 16: 965-975

A Rare Success against Alzheimer's

Kivipelto M, Håkansson K. 2017. Scientific American. 316: 32-37

Associations of CAIDE Dementia Risk Score with MRI, PIB-PET measures, and cognition

Stephen R, Liu Y, Ngandu T, Rinne JO, Kemppainen N, Parkkola R, Laatikainen T, Paajanen T, Hänninen T, Strandberg T, Antikainen R, Tuomilehto J, Keinänen Kiukaanniemi S, Vanninen R, Helisalmi S, Levälahti E, Kivipelto M, Soininen H, Solomon A. 2017. Journal of Alzheimer's disease. 59: 695-705

Baseline Telomere Length and Effects of a Multidomain Lifestyle Intervention on Cognition: The FINGER Randomized Controlled Trial

Sindi Shireen, Ngandu Tiia, Hovatta Iiris, Kåreholt Ingemar, Antikainen Riitta, Hänninen Tuomo, Levälahti Esko, Laatikainen Tiina, Lindström Jaana, Paajanen Teemu, Peltonen Markku, Khalsa Dharma Singh, Wolozin Benjamin, Strandberg Timo, Tuomilehto Jaakko, Soininen Hilkka, Kivipelto Miia, Solomon Alina. 2017. Journal of Alzheimer's disease. 59: 1459-1470

Brain amyloid load and its associations with cognition and vascular risk factors in FINGER study

Kemppainen Nina, Johansson Jarkko, Teuho Jarmo, Parkkola Riitta, Joutsa Juho, Ngandu Tiika, Solomon Alina, Stephen Ruth, Liu Yawu, Hänninen Tuomo, Paajanen Teemu, Laatikainen Tiina, Soininen Hilkka, Jula Antti, Rokka Johanna, Rissanen Eero, Vahlberg Tero, Peltoniemi Julia, Kivipelto Miia, Rinne Juha O. 2017. Neurology. 2018; 90: e206-e213

Can lifestyle changes prevent cognitive impairment?

Kivipelto Miia, Mangialasche Francesca, Ngandu Tiia. 2017. The Lancet Neurology. 16: 338-339

Cardiorespiratory fitness and brain volumes in men and women in the FINGER study

Pentikäinen Heikki, Ngandu Tiia, Liu Yawu, Savonen Kai, Komulainen Pirjo, Hallikainen Merja, Kivipelto Miia, Rauramaa Rainer, Soininen Hilkka. 2017. Age and ageing. 46: 310-313

Health-related quality of life in a multidomain intervention trial to prevent cognitive decline (FINGER)

Strandberg TE, Levälahti E, Ngandu T, Solomon A, Kivipelto M, Lehtisalo J, Laatikainen T, Soininen H, Antikainen R, Jula A, Tuomilehto J, Peltonen M, Lindström J, Rauramaa R, Pajala S, Hänninen T, Solomon A, Paajanen T, Mangialasche F, FINGER Study Group. 2017. European geriatric medicine. 8: 164-167

Improving data sharing in research with context-free encoded missing data

Hoevenaar-Blom MP, Guillemont J, Ngandu T, Beishuizen CRL, Coley N, Moll van Charante EP, Andrieu S, Kivipelto M, Soininen H, Brayne C, Meiller Y, Richard E. 2017. PLoS ONE. 12: e0182362

Midlife Work-Related Stress is Associated with Late-Life Gray Matter Volume Atrophy

Sindi, Shireen; Kåreholt, Ingemar; Spulber, Gabriela; Soininen, Hilkka; Kivipelto, Miia; Solomon, Alina. 2017. Journal of Alzheimer's disease reports. 1: 219-227

Nutrient intake and dietary changes during a 2-year multi-domain lifestyle intervention among older adults: secondary analysis of the Finnish Geriatric Intervention Study to Prevent Cognitive Impairment and Disability (FINGER) randomised controlled trial

Lehtisalo Jenni, Ngandu Tiia, Valve Päivi, Antikainen Riitta, Laatikainen Tiina, Strandberg Timo, Soininen Hilkka, Tuomilehto Jaakko, Kivipelto Miia, Lindström Jaana. 2017. British journal of nutrition. 118: 291-302

Postmenopausal hormone therapy and Alzheimer disease. A prospective cohort study

Imtiaz B, Tuppurainen M, Rikkonen T, Kivipelto M, Soininen H, Kröger H, Tolppanen A-M. 2017. Neurology. 88: 1062-1068

Risk of Alzheimer's disease among users of postmenopausal hormonetherapy: A nationwide case-control study

Imtiaz B, Taipale H, Tanskanen A, Tiihonen M, Kivipelto M, Heikkinen A-M, Tiihonen J, Soininen H, Hartikainen S, Tolppanen A-M. 2017. Maturitas. 98: 7-13

Self-rated physical fitness and estimated maximal oxygen uptake in relation to all-cause and cause-specific mortality

Solomon A, Borodulin, Ngandu T, Kivipelto M, Laatikainen T, Kulmala J. 2017. Scandinavian journal of medicine and science in sports. 2018; 28: 532-540

Terveet elämäntavat - terveet aivot

Strandberg Timo, Kivipelto Miia. 2017. Duodecim. 133: 195-200

World Wide Fingers will advance dementia prevention

Kivipelto Miia, Mangialasche Francesca, Ngandu Tiia, World Wide Fingers Network. 2017. The Lancet Neurology. 17: 27

Association of Vitamin B12, Folate, and Sulfur Amino Acids With Brain Magnetic Resonance Imaging Measures in Older Adults: A Longitudinal Population-Based Study

Hooshmand B, Mangialasche F, Kalpouzos G, Solomon A, Kåreholt I, Smith AD, Refsum H, Wang R, Mühlmann M, Ertl-Wagner B, Laukka EJ, Bäckman L, Fratiglioni L, Kivipelto M. 2016. JAMA psychiatry. 73: 606-613

Association of long-term dietary fat intake, exercise, and weight with later cognitive function in the Finnish Diabetes Prevention Study

Lehtisalo J, Lindström J, Ngandu T, Kivipelto M, Ahtiluoto S, Ilanne-Parikka P, Keinänen-Kiukaanniemi S, Eriksson JG, Uusitupa M, Tuomilehto J, Luchsinger J. 2016. Journal of nutrition health and aging. 20: 146-154

CAIDE Dementia Risk Score and biomarkers of neurodegeneration in memory clinic patients without dementia.

Enache D, Solomon A, Cavallin L, Kåreholt I, Kramberger MG, Aarsland D, Kivipelto M, Eriksdotter M, Winblad B, Jelic V. 2016. Neurobiology of aging. 42: 124-131

Defeating Alzheimer's disease and other dementias: a priority for European science and society

Winblad B, Amouyel P, Andrieu S, Ballard C, Brayne C, Brodaty H, Cedazo-Minguez A, Dubois B, Edvardsson D, Feldman H, Fratiglioni L, Frisoni GB, Gauthier S, Georges J, Graff C, Iqbal K, Jessen F, Johansson G, Jönsson L, Kivipelto M et al. 2016. The Lancet Neurology. 15: 455-532

Development and Validation of an Interactive Internet Platform for Older People: The Healthy Ageing Through Internet Counselling in the Elderly Study

Jongstra Susan, Beishuizen Cathrien, Andrieu Sandrine, Barbera Mariagnese, van Dorp Matthijs, van de Groep Bram, Guillemont Juliette, Mangialasche Francesca, van Middelaar Tessa, Moll van Charante Eric, Soininen Hilkka, Kivipelto Miia, Richard Edo. 2016. Telemedicine and e-health. 2017; 23: 1-9

Development of a Late-Life Dementia Prediction Index with Supervised Machine Learning in the Population-Based CAIDE Study

Pekkala Timo, Hall Anette, Lötjönen Jyrki, Mattila Jussi, Soininen Hilkka, Ngandu Tiia, Laatikainen Tiina, Kivipelto Miia, Solomon Alina. 2016. Journal of Alzheimer's disease. 2017; 55: 1055-1067

Estimates of global, regional, and national incidence, prevalence, and mortality of HIV, 1980-2015: the Global Burden of Disease Study 2015

GBD 2015 HIV Collaborators (including Kivipelto Miia). 2016. The Lancet HIV. 3: e361-e387

Estradiol and Cognition in the Cardiovascular Risk Factors, Aging and Dementia (CAIDE) Cohort Study

Imtiaz Bushra, Tolppanen Anna-Maija, Solomon Alina, Soininen Hilkka, Kivipelto Miia. 2016. Journal of Alzheimer's disease. 2017; 56: 453-458

From Heart Health to Brain Health: Legacy of the North Karelia Project for Dementia Research

Kivipelto Miia, Ngandu Tiia. 2016. Global heart. 11: 235-242

Healthy ageing through internet counselling in the elderly: the HATICE randomised controlled trial for the prevention of cardiovascular disease and cognitive impairment

Richard Edo, Jongstra Susan, Soininen Hilkka, Brayne Carol, Moll van Charante Eric P, Meiller Yannick, van der Groep Bram, Beishuizen Cathrien RL, Mangialasche Francesca, Barbera Mariagnese, Ngandu Tiia, Coley Nicola, Guillemont Juliette, Savy Stéphanie, Dijkgraaf Marcel GW, Peters Ron JG, van Gool Willem A, Kivipelto Miia, Andrieu Sandrine. 2016. BMJ open. 6: e010806

Leisure-Time and Occupational Physical Activity in Early and Late Adulthood in Relation to Later Life Physical Functioning

Kulmala Jenni, Ngandu Tiia, Pajala Satu, Lehtisalo Jenni, Levälahti Esko, Antikainen Riitta, Laatikainen Tiina, Oksa Heikki, Peltonen Markku, Raurama Rainer, Soininen Hilkka, Strandberg Timo, Tuomilehto Jaakko, Kivipelto Miia. 2016. Journal of physical activity and health. 13: 1079-1087

Midlife work-related stress increases dementia risk in later life: the CAIDE 30-year study

Sindi Shireen, Hagman Göran, Håkansson Krister, Kulmala Jenni, Nilsen Charlotta, Kåreholt Ingemar, Soininen Hilkka, Solomon Alina, Kivipelto Miia. 2016. Journals of gerontology series b: psychological sciences and social sciences. 2017; 72: 1044-1053

Preclinical Alzheimer's disease: Definition, natural history, and diagnostic criteria

Dubois Bruno, Hampel Harald, Feldman Howard H, Scheltens Philip, Aisen Paul, Andrieu Sandrine, Bakardjian Hovagim, Benali Habib, Bertram Lars, Blennow Kaj, Broich Karl, Cavedo Enrica, Crutch Sebastian, Dartigues Jean-Francois, Duyckaerts Charles, Epelbaum Stéphane, Frisoni Giovanni B, Gauthier Serge, Genthon Remy, Gouw Alida A et al. 2016. Alzheimer's & dementia. 12: 292-323

Web-Based Interventions Targeting Cardiovascular Risk Factors in Middle-Aged and Older People: A Systematic Review and Meta-Analysis

Beishuizen Cathrien RL, Stephan Blossom CM, van Gool Willem A, Brayne Carol, Peters Ron JG, Andrieu Sandrine, Kivipelto Miia, Soininen Hilkka, Busschers Wim B, Moll van Charante Eric P, Richard Edo. 2016. Journal of medical internet research. 18: e55

A 2 year multidomain intervention of diet, exercise, cognitive training, and vascular risk monitoring versus control to prevent cognitive decline in at-risk elderly people (FINGER): a randomised controlled trial

Ngandu Tiia, Lehtisalo Jenni, Solomon Alina, Levälahti Esko, Ahtiluoto Satu, Antikainen Riitta, Bäckman Lars, Hänninen Tuomo, Jula Antti, Laatikainen Tiina, Lindström Jaana, Mangialasche Francesca, Paajanen Teemu, Pajala Satu, Peltonen Markku, Rauramaa Rainer, Stigsdotter-Neely Anna, Strandberg T, Tuomilehto J, Soininen Hilkka, Kivipelto Miia. 2015. The Lancet. 385: 2255-2263

Advances in the prevention of Alzheimer's Disease

Sindi Shireen, Mangialasche Francesca, Kivipelto Miia. 2015. F1000 prime. published 12 May 2015: 12 p

Advances in the therapy of Alzheimer's disease : targeting amyloid beta and tau and perspectives for the future

Hampel Harald, Schneider Lon S, Giacobini Ezio, Kivipelto Miia, Sindi Shireen, Dubois Bruno, Broich Karl, Nisticò Robert, Aisen Paul S, Lista Simone. 2015. Expert review of neurotherapeutics. 15: 83-105

Cognition in the Finnish Diabetes Prevention Study

Luchsinger José A, Lehtisalo Jenni, Lindström Jaana, Ngandu Tiia, Kivipelto Miia, Ahtiluoto Satu, Ilanne-Parikka Pirjo, Keinänen-Kiukaanniemi Sirkka, Eriksson Johan G, Uusitupa Matti, Tuomilehto Jaakko, for the Finnish Diabetes Prevention Study (DPS). 2015. Diabetes research and clinical practice. 108: e63-e66

Diabetes, glycaemia, and cognition - a secondary analysis of the Finnish Diabetes Prevention Study

Lehtisalo Jenni, Lindström Jaana, Ngandu Tiia, Kivipelto Miia, Ahtiluoto Satu, Ilanne-Parikka Pirjo, Keinänen-Kiukaanniemi Sirkka, Eriksson Johan G., Uusitupa Matti, Tuomilehto Jaakko, Luchsinger Jose A, for the Finnish Diabetes Prevention Study (DPS). 2015. Diabetes/metabolism research and reviews. [epub ahead of print 18 AUG 2015]: -

Feelings of Hopelessness in Midlife and Cognitive Health in Later Life: A Prospective Population-Based Cohort Study

Håkansson Krister, Soininen Hilkka, Winblad Bengt, Kivipelto Miia. 2015. PLoS ONE. 10: e0140261

Global, regional, and national age-sex specific all-cause and cause-specific mortality for 240 causes of death, 1990-2013 : a systematic analysis for the Global Burden of Disease Study 2013

GBD 2013 Mortality and Causes of Death Collaborators incl. Miia Kivipelto. 2015. The Lancet. 385: 117-171

Global, regional, and national comparative risk assessment of 79 behavioural, environmental and occupational, and metabolic risks or clusters of risks in 188 countries, 1990-2013: a systematic analysis for the Global Burden of Disease Study 2013

Forouzanfar Mohammad H, Alexander Lily, Anderson H Ross, Bachman Victoria F, Biryukov Stan, Brauer Michael, Burnett Richard, Casey Daniel, Coates Matthew M, Cohen Aaron, Delwiche Kristen, Estep Kara, Frostad Joseph J, Kc Astha, Kyu Hmwe H, Moradi-Lakeh Maziar, Ng Marie, Slepak Erica Leigh, Thomas Bernadette A, Wagner Joseph et al. GBD 2013 Risk Factors Collaborators (incl. Kivipelto Miia). 2015. The Lancet. 386: 2287-2323

Global, regional, and national disability-adjusted life years (DALYs) for 306 diseases and injuries and healthy life expectancy (HALE) for 188 countries, 1990-2013: quantifying the epidemiological transition

Murray Christopher JL, Barber Ryan M, Foreman Kyle J, Ozgoren Ayse Abbasoglu, Abd-Allah Foad, Abera Semaw F, Aboyans Victor, Abraham Jerry P, Abubakar Ibrahim, Abu-Raddad Laith J, Abu-Rmeileh Niveen M, Achoki Tom, Ackerman Ilena N, Ademi Zanfina, Adou Arsène K, Adsuar José C, Afshin Ashkan, Agardh Emilie E, Alam Sayed Saidul, Alasfoor Deena et al., GBD 2013 DALYs and HALE Collaborators (incl. Kivipelto Miia). 2015. The Lancet. 386: 2145-2191

Global, regional, and national incidence, prevalence, and years lived with disability for 301 acute and chronic diseases and injuries in 188 countries, 1990-2013: a systematic analysis for the Global Burden of Disease Study 2013

Vos Theo, Barber Ryan M, Bell Brad, Bertozzi-Villa Amelia, Biryukov Stan, Bolliger Ian, Charlson Fiona, Davis Adrian, Degenhardt Louisa, Dicker Daniel, Duan Leilei, Erskine Holly, Feigin Valery L, Ferrari Alize J, Fitzmaurice Christina, Fleming Thomas, Graetz Nicholas, Guinovart Caterina, Haagsma Juanita, Hansen Gillian M et al, Global Burden of Disease Study 2013 Collaborators (incl. Kivipelto M). 2015. The Lancet. 386: 743-800

Lymphocytic Mitochondrial Aconitase Activity is Reduced in Alzheimer's Disease and Mild Cognitive Impairment

Mangialasche Francesca, Baglioni Mauro, Cecchetti Roberta, Kivipelto Miia, Ruggiero Carmelinda, Piobbico Danilo, Kussmaul Lothar, Monastero Roberto, Brancorsini Stefano, Mecocci Patrizia. 2015. Journal of Alzheimer's disease. 44: 649-660

Midlife CAIDE Dementia Risk Score and Dementia-Related Brain Changes up to 30 Years Later on Magnetic Resonance Imaging

Vuorinen Miika, Spulber Gabriela, Soheil Damingir, Niskanen Eini, Ngandu Tiia, Soininen Hilkka, Kivipelto Miia, Soloman Alina. 2015. Journal of Alzheimer's disease. 44: 93-101

Muistisairauksien ennaltaehkäisy

Soininen Hilkka, Kivipelto Miia. Teoksessa: Timo Erkinjuntti, Anne Remes, Juha Rinne, Hilkka Soininen(toim.) , 2015. Muistisairaudet. s. 436-445. Kustannus Oy Duodecim

New Strategy to Reduce the Global Burden of Stroke

Feigin Valery L, Krishnamurthi Rita, Bhattacharjee Rohit, Parmar Priya, Theadom Alice, Hussein Tasleem, Purohit Mitali, Hume Patria, Abbott Max, Rush Elaine, Kasabov Nikola, Crezee Ineke, Frielick Stanley, Barker-Collo Suzanne, Barber P Alan, Arroll Bruce, Poulton Richie, Ratnasabathy Yogini, Tobias Martin, Cabral Norberto et al (inc. Miia Kivipelto). 2015. Stroke. 46: 1740-1747

Pointing the FINGER at multimodal dementia prevention - Authors' reply

Kivipelto Miia, Mangialasched Francesca, Solomon Alina on behalf of the FINGER Study Group. 2015. The Lancet. 386: 1627

Target risk factors for dementia prevention : a systematic review and Delphi consensus study on the evidence from observational studies

Deckers Kay, van Boxtel Martin PJ, Schiepers Olga JG, de Vugt Marjolein, Muñoz Sánchez Juan Luis, Anstey Kaarin J, Brayne Carol, Dartigues Jean-Francois, Engedal Knut, Kivipelto Miia, Ritchie Karen, Starr John M, Yaffe Kristine, Irving Kate, Verhey Frans RJ, Köhler Sebastian. 2015. International journal of geriatric psychiatry. 30: 234-246

The CAIDE Dementia Risk Score App: The development of an evidence-based mobile application to predict the risk of dementia

Sindi Shireen, Calov Elisabeth, Fokkens Jasmine, Ngandu Tiia, Soininen Hilkka, Tuomilehto Jaakko, Kivipelto Miia. 2015. Alzheimer's & dementia : diagnosis, assessment & disease monitoring. 1: 328-333

The Nordic diet and cognition - The DR's EXTRA Study

Männikkö Reija, Komulainen Pirjo, Schwab Ursula, Heikkilä Harri M, Savonen Kai, Hassinen Maija, Hänninen Tuomo, Kivipelto Miia, Rauramaa Rainer. 2015. British journal of nutrition. 114: 231-239

The Stroke RiskometerTM App : Validation of a data collection tool and stroke risk predictor

Parmar Priya, Krishnamurthi Rita, Ikram M. Arfa, Hofman Albert, Mirza Saira S, Varakin Yury, Kravchenko Michael, Piradov Michael, Thrift Amanda G, Norrving Bo, Wang Wenzhi, Mandal Dipes Kumar, Barker-Collo Suzanne, Sahathevan Ramesh, Davis Stephen, Saposnik Gustavo, Kivipelto Miia, Sindi Shireen, Bornstein Natan M, Giroud Maurice et al. 2015. International journal of stroke. 10: 231-244

Why has therapy development for dementia failed in the last two decades?

Gauthier S, Albert M, Fox N, Goedert M, Kivipelto M, Mestre-Ferrandiz J, Middleton LT. 2015. Alzheimer's & dementia. 2016; 12: 60-64

9th Key symposium introduction: Updating Alzheimer's disease diagnosis implications for prevention and treatment

Kivipelto M, Mangialasche F, Solomon A, Johansson G, Lannfelt L, Fratiglioni L, Winblad B. 2014. Journal of internal medicine. 275: 202-203

Advances in the prevention of Alzheimer's disease and dementia

Solomon A, Mangialasche F, Richard E, Andrieu S, Bennett DA, Breteler B, Fratiglioni L, Hooshmand B, Khachaturian AS, Schneider LS, Skoog I, Kivipelto M. 2014. Journal of internal medicine. 275: 229-250

Association between mid- to late life physical fitness and dementia: evidence from the CAIDE study

Kulmala J, Solomon A, Kåreholt I, Ngandu T, Rantanen T, Laatikainen T, Soininen H, Tuomilehto J, Kivipelto M. 2014. Journal of internal medicine. 276: 296-307

Clinical trials and late-stage drug development for Alzheimer's disease: an appraisal from 1984 to 2014

Schneider LS, Mangialasche F, Andreasen N, Feldman H, Giacobini E, Jones R, Mantua V, Mecocci P, Pani L, Winblad B, Kivipelto M. 2014. Journal of internal medicine. 275: 251-283

Coronary Heart Disease and Cortical Thickness, Gray Matter and White Matter Lesion Volumes on MRI

Vuorinen Miika, Damangir Soheil, Niskanen Eini, Miralbell Julia, Rusanen Minna, Spulber Gabriela, Soininen Hilkka, Kivipelto Miia, Solomon Alina. 2014. PLoS ONE. 9: e109250, 1-9

Future directions in Alzheimer's disease from risk factors to prevention

Imtiaz Bushra, Tolppanen Anna-Maija, Kivipelto Miia, Soininen Hilkka. 2014. Biochemical pharmacology. 88: 661-670

Heart diseases and long-term risk of dementia and Alzheimer's disease: a population-based CAIDE study

Rusanen Minna, Kivipelto Miia, Levälahti Esko, Laatikainen Tiina, Tuomilehto Jaakko, Soininen Hilkka, Ngandu Tiia. 2014. Journal of Alzheimer's disease. 42: 183-191

Late-life cynical distrust, risk of incident dementia, and mortality in a population-based cohort

Neuvonen Elisa, Rusanen Minna, Solomon Alina, Ngandu Tiia, Laatikainen Tiina, Soininen Hilkka, Kivipelto Miia, Tolppanen Anna-Maija. 2014. Neurology. 82: 2205-2212

Leisure-time physical activity from mid- to late life, body mass index, and risk of dementia

Tolppanen Anna-Maija, Solomon Alina, Kulmala Jenni, Kåreholt Ingemar, Ngandu Tiia, Rusanen Minna, Laatikainen Tiina, Soininen Hilkka, Kivipelto Miia. 2014. Alzheimer's & dementia. Epub ahead of print: -

Modifiable lifestyle factors in dementia: A systematic review of longitudinal observational cohort studies

Di Marco Luigi Yuri, Marzo Alberto, Munoz-Ruiz Miguel, Arfan Ikram M, Kivipelto Miia, Ruefenacht Daniel, Venneri Annalena, Soininen Hilkka, Wanke Isabel, Ventikos Yiannis A, Frangi Alejandro F. 2014. Journal of Alzheimer's disease. 42: 119-135

Oophorectomy, Hysterectomy, and Risk of Alzheimer's Disease: A Nationwide Case-Control Study

Imtiaz Bushra, Tuppurainen Marjo, Tiihonen Miia, Kivipelto Miia, Soininen Hilkka, Hartikainen Sirpa, Tolppanen Anna-Maija. 2014. Journal of Alzheimer's disease. 42: 575-581

Vitamin D in relation to cognitive impairment, cerebrospinal fluid biomarkers, and brain volumes

Hooshmand Babak, Lökk Johan, Solomon Alina, Mangialasche Francesca, Miralbell Julia, Spulber Gabriela, Annerbo Sylvia, Andreasen Niels, Winblad Bengt, Cedazo-Minguez Angel, Wahlund Lars-Olof, Kivipelto Miia. 2014. Journals of gerontology series a: biological sciences and medical sciences. -: 7 s.

Changes in vascular factors 28 years from midlife and late-life cortical thickness

Vuorinen M, Kåreholt I, Julkunen V, Spulber G, Niskanen E, Paajanen T, Soininen H, Kivipelto M, Solomon A. 2013. Neurobiology of aging. 34: 100-109

Cholesterol, statins, and late-life cognitive disorders.

Solomon A, Kivipelto M. Teoksessa: Yaffe Kristine(toim.) , 2013. Chronic Medical Disease and Cognitive Aging. Toward a healthy body and brain. s. 13-39. Oxford University Press

Chronic obstructive pulmonary disease and asthma and the risk of mild cognitive impairment and dementia: a population based CAIDE study

Rusanen M, Ngandu T, Laatikainen T, Tuomilehto J, Soininen H, Kivipelto M. 2013. Current alzheimer research. 10: 549-555

Classification and prediction of clinical diagnosis of Alzheimer's disease based on MRI and plasma measures of alpha-/gamma-tocotrienols and gamma-tocopherol

Mangialasche F, Westman E, Kivipelto M, Muehlboeck J-S, Cecchetti R, Baglioni M, Tarducci R, Gobbi G, Floridi P, Soininen H, Kloszewska I, Tsolaki M, Vellas B, Spenger C, Lovestone S, Wahlund L-O, Simmons A, Mecocci P. 2013. Journal of internal medicine. 273: 602-621

Diagnostic power of 24S-hydroxycholesterol in cerebrospinal fluid: Candidate marker of brain health

Leoni V, Solomon A, Lövgren-Sandholm A, Blennow K, Hansson O, Wahlund L-O, Kivipelto M, Björkhem I. 2013. Journal of Alzheimer's disease. 36: 739-747

GRN variant rs5848 reduces plasma and brain levels of granulin in Alzheimer's disease patients

Kämäläinen A, Viswanathan J, Natunen T, Helisalmi S, Kauppinen T, Pikkarainen M, Pursiheimo J-P, Alafuzoff I, Kivipelto M, Haapasalo A, Soininen H, Herukka S-K, Hiltunen M. 2013. Journal of Alzheimer's disease. 33: 23-27

History of medically treated diabetes and risk of Alzheimer disease in a nationwide case-control study

Tolppanen Anna-Maija, Lavikainen Piia, Solomon Alina, Kivipelto Miia, Uusitupa Matti, Soininen Hilkka, Hartikainen Sirpa. 2013. Diabetes care. 36: 2015-2019

Incidence of stroke in people with Alzheimer disease. A national register-based approach

Tolppanen Anna-Maija, Lavikainen Piia, Solomon Alina, Kivipelto Miia, Soininen Hilkka, Hartikainen Sirpa. 2013. Neurology. 80: 353-358

Midlife and late-life body mass index and late-life dementia: results from a prospective population-based cohort

Tolppanen A-M, Ngandu T, Kåreholt I, Laatikainen T, Rusanen M, Soininen H, Kivipelto M. 2013. Journal of Alzheimer's disease. online: -

Muistisairauksien ehkäisy ja riskitekijät

Kivipelto M, Ngandu T. Teoksessa: Hallikainen M, Mönkäre R, Nukari T, Folder M(toim.) , 2013. Muistisairaan kuntouttava hoito. s. 26-29. Kustannus Oy Duodecim

Plasma homocysteine, Alzheimer and cerebrovascular pathology: a population-based autopsy study

Hooshmand B, Polvikoski T, Kivipelto M, Tanskanen M, Myllykangas L, Erkinjuntti T, Mäkelä M, Oinas M, Paetau A, Scheltens P, van Straaten ECW, Sulkava R, Solomon A. 2013. Brain. 136: 2707-2716

Prevention of Alzheimer's Disease: Moving backward through the lifespan

Solomon A, Kivipelto M, Soininen H. 2013. Journal of Alzheimer's disease. 33: S465-S469

Risk factors for incident dementia in the very old

Wallin K, Boström G, Kivipelto M, Gustafson Y. 2013. International psychogeriatrics. 25: 1135-43

Serum levels of vitamin E forms and risk of cognitive impairment in a Finnish cohort of older adults

Mangialasche F, Solomon A, Kåreholt I, Hooshmand B, Cecchetti R, Fratiglioni L, Soininen H, Laatikainen T, Mecocci P, Kivipelto M. 2013. Experimental gerontology. 48: 1428-1435

The Finnish Geriatric intervention study to prevent cognitive impairment and disability (FINGER): Study design and progress

Kivipelto M, Solomon A, Ahtiluoto S, Ngandu T, Lehtisalo J, Antikainen R, Bäckman L, Hänninen T, Jula A, Laatikainen T, Lindström J, Mangialasche F, Nissinen A, Paajanen T, Pajala S, Peltonen M, Rauramaa R, Stigsdotter-Neely A, Strandberg T, Tuomilehto J, Soininen H. 2013. Alzheimer's & dementia. 9: 657-665

Validity of dementia and Alzheimer disease diagnoses in Finnish national registers

Solomon A, Ngandu T, Soininen H, Hallikainen M, Kivipelto M, Laatikainen T. 2013. Alzheimer's & dementia. Epub: 1-7

Associations between serum homocysteine, holotranscobalamin, folate and cognition in the elderly: a longitudinal study

Hooshmand B, Solomon A, Kåreholt I, Rusanen M, Hänninen T, Leivistä J, Winblad B, Laatikainen T, Soininen H, Kivipelto M. 2012. Journal of internal medicine. 271: 204-212

Cortical thickness in frontotemporal dementia, mild cognitive impairment, and Alzheimer's Disease

Hartikainen P, Räsänen J, Julkunen V, Niskanen E, Hallikainen M, Kivipelto M, Vanninen R, Remes AM, Soininen H. 2012. Journal of Alzheimer's disease. 30: 857-874

Dementia after age 75: Survival in different severity stages and years of life lost

Rizzuto D, Bellocco R, Kivipelto M, Clerici F, Wimo A, Fragtiglioni L. 2012. Current alzheimer research. 9: 795-800

Dementia prevention: current epidemiological evidence and future perspective

Mangialasche F, Kivipelto M, Solomon M, Fratiglioni L. 2012. Alzheimer's research and therapy. 4: 1-8

Differences in brain cholestero metabolism and insulin in two subgroups of patients with different CSF biomarkers but similar white matter lesions suggest different pathogenic mechanisms

Besga A, Cedazo-Minguez A, Kåreholt I, Solomon A, Björkhem I, Winblad B, Leoni V, Hooshmand B, Spulber G, Gonzales-Pinto A, Kivipelto M, Wahlund LO. 2012. Neuroscience letters. 510: 121-126

Education halves the risk of dementia due to apolipoprotein epsilon4 allele: a collaborative study from the Swedish Brain Power initiative

Wang H-X, Gustafson DR, Kivipelto M, Pedersen NL, Skoog I, Windblad B, Fratiglioni L. 2012. Neurobiology of aging. 33: 1007.e1-1007.e7

Evolution of global and local grey matter atrophy on serial MRI scans during the progression from MCI to AD

Spulber G, Niskanen E, MacDonald S, Kivipelto M, Ferreira Padilla D, Julkunen V, Hallikainen M, Vanninen R, Wahlund L-O, Soininen H. 2012. Current alzheimer research. 9: 516-524

Grey matter and cognitive patterns in cognitive impaired subjects using CSF biomarker cut-offs

Miralbell J, Spulber G, Hooshmand B, Besga A, Mataro M, Cedazo-Minguez A, Kivipelto M, Wahlund L-O. 2012. Journal of Alzheimer's disease. 29: 741-749

Methodological challenges in designing dementia prevention trials - The European Dementia Prevention Initiative (EDPI)

Richard E, Andrieu S, Solomon A, Mangialasche F, Ahtiluoto S, Moll van Charante EP, Coley N, Fratiglioni L, Stigsdotter Neely A, Vellas B, van Gool WA, Kivipelto M. 2012. Journal of the neurological sciences. 322: 64-70

Midlife Vascular Risk Factors and Alzheimer's Disease: Evidence from Epidemiological Studies

Tolppanen AM, Solomon A, Soininen H, Kivipelto M. 2012. Journal of Alzheimer's disease. 32: 531-40

Midlife rheumatoid arthritis increases the risk of cognitive impairment two decades later: A population-based study

Wallin K, Solomon A, Kåreholt I, Tuomilehto J, Soininen H, Kivipelto M. 2012. Journal of Alzheimer's disease. 31: 669-676

Practical Lessons from Amyloid Immunotherapy Trials in Alzheimer Disease

Solomon A, Akenine U, Andreasen N, Mangialasche F, Wimo A, Jelic V, Kivipelto M, Winblad B. 2012. Current alzheimer research. 9: 1126-1134

Structural MRI in frontotemporal dementia: Comparisons between hippocampal volumetry, tensor-based morphometry and voxel-based morphometry

Munoz-Ruiz MA, Hartikainen P, Koikkalainen J, Wolz R, Julkunen V, Niskanen E, Herukka S-K, Kivipelto M, Vanninen R, Rueckert D, Liu Y, Lötjönen J, Soininen H. 2012. PLoS ONE. 7: e52531

Structural brain changes and cognition in relation to markers of vascular dysfunction

Miralbell J, Soriano JJ, Spulber G, Lopez-Cancio E, Arenillas JF, Bargallo N, Galan A, Barrios MT, Caceres C, Alzamora MT, Pera G, Kivipelto M, Wahlund L-O, Davalos A, Mataro M. 2012. Neurobiology of aging. 33: 1003.e9-1003.e17

Voiko muistisairauksia ehkäistä?

Kivipelto M, Ngandu T, Soininen H, Laatikainen T. Teoksessa: Reivinen J, Vähäkylä L(toim.) , 2012. Kansan terveys, yksilön hyvinvointi. s. 91-107. Gaudeamus Oy

Changes in vascular risk factors from midlife to late life and white matter lesions: A 20-year follow-up study

Vuorinen Miika, Solomon Alina, Rovio Suvi, Nieminen Lasse, Kåreholt Ingemar, Tuomilehto Jaakko, Soininen Hilkka, Kivipelto Miia. 2011. Dementia and geriatric cognitive disorders. 31: 119-125

Cost-effectiveness of a health intervention program with risk reductions for getting demented: Results of a Markow model in a Swedish/Finnish setting

Zhang Y, Kivipelto M, Solomon A, Wimo A. 2011. Journal of Alzheimer's disease. 26: 735-744

Diffusion tensor imaging and Tract-Based Spatial Statistics in Alzheimer's disease and mild cognitive impairment

Liu Y, Spulber G, Lehtimäki KK, Könönen M, Hallikainen I, Gröhn H, Kivipelto M, Hallikainen M, Vanninen R, Soininen H. 2011. Neurobiology of aging. 32: 1558-1571

Heavy smoking in midlife and long-term risk of Alzheimer disease and vascular dementia

Rusanen Minna, Kivipelto Miia, Quesenberry Jr Charles P, Zhou Jufen, Whitmer Rachel A. 2011. Archives of internal medicine. 171: 333-339

Metabolome in progression to Alzheimer's disease

Oresic M, Hyötyläinen T, Herukka S-K, Sysi-Aho M, Mattila I, Seppänan-Laakso T, Julkunen V, Gopalacharyulu PV, Hallikainen M, Koikkalainen J, Kivipelto M, Helisalmi S, Lötjönen J, Soininen H. 2011. Translational psychiatry. 1: e57

Midlife healthy-diet index and late-life dementia and Alzheimer's disease

Eskelinen Marjo, Ngandu Tiia, Tuomilehto Jaakko, Soininen Hilkka, Kivipelto Miia. 2011. Dementia and geriatric cognitive disorders. 1: 103-112

New insights into Alzheimer's disease progression: A combined TMS and structural MRI study

Niskanen Eini, Könönen Mervi, Määttä Sara, Hallikainen Merja, Kivipelto Miia, Casarotto Silvia, Massimini Marcello, Vanninen Ritva, Mervaala Esa, Karhu Jari, Soininen Hilkka. 2011. PLoS ONE. 6: e26113

Alzheimer's disease: clinical trials and drug development

Mangialasche F, Solomon A, Winblad B, Mecocci P & Kivipelto M. 2010. The Lancet Neurology. 9: 702-16

Caffeine as a protective factor in dementia and Alzheimer's Disease

Eskelinen MH, Kivipelto M. 2010. Journal of Alzheimer's disease. 20: S167-S174

Diabetes, Alzheimer disease, and vascular dementia: a population-based neuropathologic study

Ahtiluoto S, Polvikoski T, Peltonen M, Solomon A, Tuomilehto J, Winblad B, Sulkava R & Kivipelto M. 2010. Neurology. 75: 1195-1202

Differences in cortical thickness in healthy controls, subjects with mild cognitive impairment, and Alzheimer's Diseaes patients: A longitudinal study

Julkunen V, Niskanen E, Koikkalainen J, Herukka SK, Pihlajamäki M, Hallikainen H, Kivipelto M, Muehlboeck S, Evans AC, Vanninen R & Soininen H. 2010. Journal of Alzheimer's disease. 21: 1141-1151

HPA axis dysregulation associated to apolipoprotein E4 genotype in Alzheimer's Disease

Gil-Bea FJ, Aisa B, Solomon A, Solas M, del Carmen Mugueta M, Winblad B, Kivipelto M, Cedazo-Minguez A, Ramirez MJ. 2010. Journal of Alzheimer's disease. 22: 829-838

Homocysteine and holotranscobalamin and the risk of Alzheimer disease

Hooshmand B, Solomon A, Kåreholt I, Leivistä J, Rusanen M, Ahtiluoto S, Winblad B, Laatikainen T, Soininen H & Kivipelto M. 2010. Neurology. 75: 1408-1414

Insulin levels are decreased in the cerebrospinal fluid of womwn with prodomal Alzheimer's disease

Gil-Bea FJ, Solas M, Solomon A, Mugueta C, Winblad B, Kivipelto M, Ramirez MJ, Cedazo-Minguez A. 2010. Journal of Alzheimer's disease. 22: 405-413

Links between ApoE, brain cholesterol metabolism, tau and amyloid beeta-peptide in patients with cognitive impairment

Leoni V, Solomon A & Kivipelto M. 2010. Biochemical society transactions. 38: 1021-2025

Lipid-Lowering Treatment Is Related to Decreased Risk of Dementia: A Population-Based Study (FINRISK)

Solomon A, Sippola R, Soininen H, Wolozin B, Tuomilehto J, Laatikainen T & Kivipelto M. 2010. Neurodegenerative diseases. 7: 180-182

Midlife smoking, apolipoprotein E and risk of dementia and Alzheimer's disease: A population-based cardiovascular risk factors, aging and dementia study

Rusanen M, Rovio S, Ngandu T, Nissinen A, Tuomilehto J, Soininen H, Kivipelto M. 2010. Dementia and geriatric cognitive disorders. 30: 277-284

Muistisairaudet

Erkinjuntti T, Rinne J & Soininen H. 2010. . . WS Bookwell Oy

Nonpharmacological therapies in Alzheimer's Disease: A systematic review of efficacy

Olazaran J, Reisberg B, Clare L, Cruz L, Pena-Casanova J, del Ser T, Woods B, Beck C, Auer S, Lai C, Spector A, Fazio S, Bond J, Kivipelto M et al.. 2010. Dementia and geriatric cognitive disorders. 30: 161-178

Randomized controlled trial of atorvastatin in mild to moderate Alzheimer disease: LEADe

Feldman HH, Doody RS, Kivipelto M, Sparks DL, Waters DD, Jones RW, Schwam E, Schindler R et al. 2010. Neurology. 74: 956-964

Stroke: Working toward to prioritized world agenda

Hachinski V, Donnan GA, Gorelick PB, Hacke W, Cramer SC, Kaste M, Fisher M, Brainin M et al. 2010. Stroke. 41: 1084-1099

The effect of midlife physical activity on structural brain changes in the elderly

Rovio S, Spulber G, Nieminen LJ, Niskanen E, Winblad B, Tuomilehto J, Nissinen A, Soininen H & Kivipelto M. 2010. Neurobiology of aging. 31: 1927-1936

Use of angiotensin receptor blockers and risk of dementia in a predominantly male population: prospective cohort analysis

Li NC, Lee A, Whitmer RA, Kivipelto M, Lawler E, Kazis LE & Wolozin B. 2010. BMJ (INTERNATIONAL). 340: 1-10

Whole brain atrophy rate predicts progression from MCI to Alzheimer's disease

Spulber G, Niskanen E, MacDonald S, Smilovici O, Chen K, Reiman EM, Jauhiainen AM, Hallikainen M, Tervo S, Wahlund LO, Vanninen R, Kivipelto M, Soininen H. 2010. Neurobiology of aging. 31: 1601-1605

Association between mid-life marital status and cognitive function in later life: population based cohort study

Håkansson K, Rovio S, Helkala E-L, Vilska A-R, Windlad B, Soininen H, Nissinen A, Mohammed AH, Kivipelto M, Soininen H. 2009. BMJ. 339:

Cortical thickness analysis to detect progressive mild cognitive impairment: a reference to Alzheimer's disease

Julkunen V, Niskanen E, Muehlboeck S, Pihlajamäki M, Könönen M, Hallikainen M, Kivipelto M, Tervo S, Vanninen R, Evans A, Soininen H, Soininen H. 2009. Dementia and geriatric cognitive disorders. 28: 404-412

Midlife coffee and tea drinking and the risk of late-life dementia: a population-based CAIDE study

Eskelinen MH, Ngandu T, Tuomilehto J, Soininen H, Kivipelto M, Soininen H. 2009. Journal of Alzheimer's disease. 16: 85-91

Midlife serum cholesterol and increased risk of Alzheimer's and vascular dementia three decades later

Solomon A, Kivipelto M, Wolozin B, Zhou J, Whitmer RA. 2009. Dementia and geriatric cognitive disorders. 28: 75-80

Plasma levels of 24S-hydroxycholesterol reflect brain volumes in patients without objective cognitive impairment but not in those with Alzheimer's disease

Solomon A, Leoni V, Kivipelto M, Besga A, Öksengård AR, Julin P, Svensson L, Wahlund L-O, Andreasen N, Winbland B, Soininen H, Björkhem I, Soininen H. 2009. Neuroscience letters. : 89-93

Serum total cholesterol, statins and cognition in non-demented elderly

Solomon A, Kåreholt I, Ngandu T, Wolozin B, Macdonald SW, Winbland B, Nissinen A, Tuomilehto J, Soininen H, Kivipelto M, Soininen H. 2009. Neurobiology of aging. 30: 1006-1009

A multi-metabolite analysis of serum by 1H NMR spectroscopy: Early systemic signs of Alzheimer's disease

Tukiainen T, Tynkkynen T, Mäkinen V-P, Jylänki P, Kangas A, Hokkanen J, Vehtari A, Gröhn O, Hallikainen M, Soininen H, Kivipelto M, Groop P-H, Kaski K, Laatikainen R, Soininen P, Pirttilä T, Ala-Korpela M, Soininen H, Pirttilä. 2008. Biochemical and biophysical research communications. 375: 356-361

Apolipoprotein E epsilon4 allele is associated with increased atrophy in progressive mild cognitive impairment: a voxel-based morphometric study

Hämäläinen A, Grau-Olivares M, Tervo S, Niskanen E, Pennanen C, Huuskonen J, Kivipelto M, Hänninen T, Tapiola M, Vanhanen M, Hallikainen M, Helkala E-L, Nissinen A, Vanninen RL, Soininen H, Hallikainen M, Soininen H. 2008. Neurodegenerative diseases. 5: 186-189

Apolipoprotein E epsilon4 magnifiles lifestyle risks for dementia: a population-based study

Kivipelto M, Rovio S, Ngandu T, Kåreholt I, Eskelinen M, Wiblad B, Hachinski V, Cedazo-Minguez A, Soininen H, Tuomilehto J, Nissinen A, Soininen H. 2008. Journal of cellular and molecular medicine. 12: 2762-2771

Differential hypometabolism patterns according to mild cognitive impairment subtypes

Jauhiainen AM, Kangasmaa T, Rusanen M, Niskanen E, Tervo S, Kivipelto M, Vanninen RL, Kuikka JT, Soininen H, Soininen H. 2008. Dementia and geriatric cognitive disorders. 26: 490-498

Fat intake at midlife and cognitive impairment later in life: a population-based CAIDE study

Eskelinen MH, Ngandu T, Helkala EL, Tuomilehto J, Nissinen A, Soininen H, Kivipelto M, Soininen H. 2008. International journal of geriatric psychiatry. 23: 741-747

MRI of hippocampus and entorhinal cortex in mild cognitive impairment: a follow-up study

Tapiola T, Pennanen C, Tapiola M, Tervo S, Kivipelto M, Hänninen T, Pihlajamäki M, Laakso MP, Hallikainen M, Hämäläinen A, Vanhanen M, Helkala EL, Vanninen R, Nissinen A, Rossi R, Frisoni GB, Soininen H. 2008. Neurobiology of aging. 29: 31-38

Alcohol drinking and cognitive functions: findings from the cardiovascular risk factors aging and dementia (CAIDE) study

Ngandu T, Helkala E-L, Soininen H, Winblad B, Tuomilehto J, Nissinen A, Kivipelto M. 2007. Dementia and geriatric cognitive disorders. 23: 140-149

Carotid intima-media thickness and cognitive function in elderly women: a population-based study

Komulainen P, Kivipelto M, Lakka TA, Hassinen M, Helkala E-L, Patja K, Nissinen A, Rauramaa R. 2007. Neuroepidemiology. 28: 207-213

Education and dementia: What lies behind the association?

Ngandu T, von Strauss E, Helkala E-L, Winblad B, Nissinen A, Tuomilehto J, Soininen H, Kivipelto M, Soininen H. 2007. Neurology. 69: 1442-1450

Levels of ApoE in cerebrospinal fluid are correlated with Tau and 24S-hydroxycholesterol in patients with cognitive disorders

Shafaati M, Solomon A, Kivipelto M, Björkhem I, Leoni V. 2007. Neuroscience letters. 425: 78-82

Metabolic syndrome and cognitive function: a population-based follow-up study in elderly women

Komulainen P, Lakka TA, Kivipelto M, Hassinen M, Helkala E-L, Haapala I, Nissinen A, Rauramaa R. 2007. Dementia and geriatric cognitive disorders. 23: 29-34

Serum cholesterol changes after midlife and late-life cognition. Twenty-one-year follow-up study

Solomon A, Kåreholt I, Ngandu T, Winblad B, Nissinen A, Tuomilehto J, Soininen H, Kivipelto M. 2007. Neurology. 68: 751-756

Serum high sensitivity C-reactive protein and cognitive function in elderly women

Komulainen P, Lakka TA, Kivipelto M, Hassinen M, Penttilä IM, Helkala E-L, Gylling H, Nissinen A, Rauramaa R. 2007. Age and ageing. 36: 443-448

Voxel-based morphometry to detect brain atrophy in progressive mild cognitive impairment

Hämäläinen A, Tervo S, Grau-Olivares M, Niskanen E, Pennanen C, Huuskonen J, Kivipelto M, Hänninen T, Tapiola M, Vanhanen M, Hallikainen M, Helkala E-L, Nissinen A, Vanninen R, Soininen H, Hämäläinen A, Tervo S, Vanhanen M, Hallikainen M, Soininen H. 2007. Neuroimage. 37: 1122-1131

Work-related physical activity and the risk of dementia and Alzheimer's disease

Rovio S, Kåreholt I, Viitanen M, Winblad B, Tuomilehto J, Soininen H, Nissinen A, Kivipelto M, Soininen H. 2007. International journal of geriatric psychiatry. 22: 874-882

Alzheimer's Disease: back to the future

Kivipelto M, Solomon A, Winbland B. 2006. Acta neurologica scandinavica: supplementum. 114: 119-120

Body mass index and the risk of Parkinson disease

Hu G, Jousilahti P, Nissinen A, Antikainen R, Kivipelto M, Tuomilehto J. 2006. Neurology. 67: 1955-1959

Cholesterol as a risk factor for Alzheimer¿s disease - epidemiological evidence

Kivipelto M, Solomon A. 2006. Acta neurologica scandinavica: supplementum. 114: 50-57

Fat intake at midlife and risk of dementia and Alzheimer¿s disease: A population-based study

Laitinen MH, Ngandu T, Rovio S, Helkala E-L, Uusitalo U, Viitanen M, Nissinen A, Tuomilehto J, Soininen H, Kivipelto M. 2006. Dementia and geriatric cognitive disorders. 22: 99-107

Risk score for the prediction of dementia risk in 20 years among middle aged people: a longitudinal, population-based study

Kivipelto M, Ngandu T, Laatikainen T, Winblad B, Soininen H, Tuomilehto J. 2006. The Lancet Neurology. 5: 735-741

The effect of apolipoprotein polymorphism on brain in mild cognitive impairment: A voxel-based morphometric study

Pennanen C, Testa C, Boccardi M, Laakso MP, Hallikainen M, Helkala E-L, Hänninen T, Kivipelto M, Könönen M, Nissinen A, Tervo S, Vanhanen M, Vanninen R, Frisoni GB, Soininen H, Könönen M, Hallikainen M, Tervo S, Soininen H, Laakso MP. 2006. Dementia and geriatric cognitive disorders. 22: 60-66

The new cholesterol controversy - a little bit of history repeating?

Kivipelto M, Solomon A, Blennow K, Olsson AG, Winblad B. 2006. Acta neurologica scandinavica: supplementum. 114: 1-2

A voxel based morphometry study on mild cognitive impairment

Pennanen C, Testa C, Laakso MP, Hallikainen M, Helkala E-L, Hänninen T, Kivipelto M, Könönen M, Nissinen A, Tervo S, Vanhanen M, Vanninen R, Frisoni GB, Soininen H, Laakso MP, Könönen M, Soininen H. 2005. Journal of neurology neurosurgery and psychiatry. 76: 11-14

Can mild cognitive impairment predict Alzheimer¿s disease?

Soininen H, Tuomainen S, Pennanen C, Hänninen T, Kivipelto M, Soininen H. Teoksessa: Hanin I, Cacabelos R, Fisher A(toim.) , 2005. Recent Progress in Alzheimer¿s and Parkinson¿s Disease. s. 191-195. Taylor & Francis

High cholesterol diet induces tau hyperphosphorylation in apolipoprotein E deficient mice

Rahman A, Akterin S, Flores-Morales A, Crisby M, Kivipelto M, Schultzberg M, Cedazo-Mínguez A. 2005. Febs letters. 579: 6411-6416

Leisure-time physical activity at midlife and the risk of dementia and Alzheimer's disease

Rovio S, Kåreholt I, Helkala E-L, Viitanen M, Winblad B, Tuomilehto J, Soininen H, Nissinen A, Kivipelto M. 2005. The Lancet Neurology. 4: 705-711

Obesity and vascular risk factors at midlife and the risk of dementia and Alzheimer¿s disease

Kivipelto M, Ngandu T, Fratiglioni L, Viitanen M, Kåreholt I, Winblad B, Helkala E-L, Tuomilehto J, Soininen H, Nissinen A, Soininen H. 2005. Archives of neurology. 62: 1556-1560

Acetylcholinesterase and its inhibition in Alzheimer Disease

Lane RM, Kivipelto M, Greig NH, Kivipelto M. 2004. Clinical neuropharmacology. 27: 141-149

Alcohol drinking in middle age and subsequent risk of mild cognitive impairment and dementia in old age: a prospective population based study

Anttila T, Helkala E-L, Viitanen M, Kåreholt I, Fratiglioni L, Winblad B, Soininen H, Tuomilehto J, Nissinen A, Kivipelto M, Soininen H. 2004. BMJ international edition. 329: 539-544

Alzheimerin taudin genetiikka

Hiltunen M, Helisalmi S, Kivipelto M, Soininen H, Hiltunen M, Helisalmi S, Soininen H. 2004. Duodecim. 120: 2425-2431

Hippocampus and entorhinal cortex in mild cognitive impairment and early AD

Pennanen C, Kivipelto M, Tuomainen S, Hartikainen P, Hänninen T, Laakso MP, Hallikainen M, Vanhanen M, Nissinen A, Helkala E-L, Vainio P, Vanninen R, Partanen K, Soininen H, Pennanen C, Kivipelto M, Tuomainen S, Hänninen T, Hallikainen M, Vanhanen M. 2004. Neurobiology of aging. 25: 303-310

Incidence and risk factors for mild cognitive impairment: a population-based three-year follow-up study of cognitively healthy elderly subjects

Tervo S, Kivipelto M, Hänninen T, Vanhanen M, Hallikainen M, Mannermaa A, Soininen H, Tervo S, Kivipelto M, Hänninen T, Vanhanen M, Hallikainen M, Soininen H. 2004. Dementia and geriatric cognitive disorders. 17: 196-203

Mild cognitive impairment - beyond controversies, towards a consensus: report ot the international working group on mild cognitive impairment

Winblad B, Palmer K, Kivipelto M, Jelic V, Fratiglioni L, Wahlund L-O, Nordberg A, Bäckman L, Albert M, Almkvist O, Arai H, Basun H, Blennow K, de Leon M, Decarli C, Erkinjuntti T, Giacobini E, Graff C, Hardy J, Jack C, Jorm A, Ritchie K, van Duijn C, Visser P, Petersen RC, Kivipelto M. 2004. Journal of internal medicine. 256: 240-246

Risk and protective effects of the APOE gene towards Alzheimer¿s disease in the Kungsholmen project: variation by age and sex

Qiu C, Kivipelto M, Aguero-Torres H, Winblad B, Fratiglioni L, Kivipelto M. 2004. Journal of neurology neurosurgery and psychiatry. 75: 828-833

Serum lipids and hippocampal volume: the link to Alzheimer¿s disease?

Wolf H, Hensel A, Arendt T, Kivipelto M, Winblad B, Gertz H-J, Kivipelto M. 2004. Annals of neurology. 56: 745-749

Serum testosterone levels in males with Alzheimer¿s disease

Pennanen C, Laakso MP, Kivipelto M, Ramberg J, Soininen H, Laakso MP, Soininen H. 2004. Journal of neuroendocrinology. 16: 95-98

Utilization of cognitive support in episidic free recall as a function of apolipoprotein E and vitamin B12 or folate among adults aged 75 years and older

Bunce D, Kivipelto M, Wahlin Å, Kivipelto M. 2004. Neuropsychology. 18: 362-370

Apolipoprotein E epsilon4 allele, elevated midlife total cholesterol level, and high midlife systolic blood pressure are independent risk factors for late-life Alzheimer disease

Kivipelto M, Helkala E-L, Laakso MP, Hänninen T, Hallikainen M, Alhainen K, Iivonen S, Mannermaa A, Tuomilehto J, Nissinen A, Soininen H. 2002. Annals of internal medicine. 137: 149-155

Hypertension and hypercholesterolaemia as risk factors for Alzheimer¿s disease: potential for pharmacological intervention

Kivipelto M, Laakso MP, Tuomilehto J, Nissinen A, Soininen H. 2002. Cns drugs. 16: 435-444

Hypertension and white matter lesions of the brain

Kivipelto M, Soininen H, Tuomilehto J. 2002. Journal of hypertension. 20: 387-389

Midlife income, occupation, APOE status, and dementia

Anttila T, Helkala E-L, Kivipelto M, Hallikainen M, Alhainen K, Heinonen H, Mannermaa A, Tuomilehto J, Soininen H, Nissinen A. 2002. Neurology. 59: 887-893

Usefulness of repeated presentation of Mini-Mental State Examination as a diagnostic procedure - a population-based study

Helkala E-L, Kivipelto M, Hallikainen M, Alhainen K, Heinonen H, Tuomilehto J, Soininen H, Nissinen A. 2002. Acta neurologica scandinavica. 106: 341-346

Vascular Risk Factors in Alzheimer¿s Disease and Mild Cognitive Impairment

Kivipelto M. 2002. Kuopion yliopisto. Neurologian klinikan julkaisusarja, No

Vascular risk factors, ApoE epsilon4 allele, and gender and the risk of Alzheimer¿s disease: perspectives on prevention

Kivipelto M, Helkala E-L, Nissinen A, Soininen H, Tuomilehto J. 2002. Drug development research. 56: 85-94

APOE-epsilon4 is associated with weight loss in women with AD. A population-based study

Vanhanen M, Kivipelto M, Koivisto K, Kuusisto J, Mykkänen L, Helkala E-L, Hänninen T, Kervinen K, Kesäniemi YA, Laakso MP, Soininen H, Laakso M. 2001. Neurology. 56: 655-659

Midlife vascular risk factors and Alzheimer¿s disease in later life: longitudinal, population based study

Kivipelto M, Helkala E-L, Laakso MP, Hänninen T, Hallikainen M, Alhainen K, Soininen H, Tuomilehto J, Nissien A. 2001. BMJ international edition. 322: 1447-1451

Midlife vascular risk factors and late-life mild cognitive impairment. A population-based study

Kivipelto M, Helkala E-L, Hänninen T, Laakso MP, Hallikainen M, Alhainen K, Soininen H, Tuomilehto J, Nissinen A. 2001. Neurology. 56: 1683-1689

Tarkenna hakuasi

Projektit

Awards

Avainsanat

27‐hydroxycholesterol promotes oligodendrocyte maturation: Implications for hypercholesterolemia‐associated brain white matter changes

Age-related differences in the functional topography of the locus coeruleus and their implications for cognitive and affective functions

Association of Sarcopenia and Its Defining Components with the Degree of Cognitive Impairment in a Memory Clinic Population

Combined Evidence for a Long-Term, Clinical Slowing Effect of Multinutrient Intervention in Prodromal Alzheimer’s Disease: Post-Hoc Analysis of 3-Year Data from the LipiDiDiet Trial

Communication about diagnosis, prognosis, and prevention in the memory clinic: perspectives of European memory clinic professionals

Dementia prevention in memory clinics: recommendations from the European task force for brain health services

Latin American Initiative for Lifestyle Intervention to Prevent Cognitive Decline (LatAm‐FINGERS): Study design and harmonization

Longitudinal study of Alzheimer's disease biomarkers, allostatic load, and cognition among memory clinic patients

Markers of vitamin B12 status in relation to cerebrospinal fluid biomarkers of Alzheimer's disease and cognitive performance

Multimodal Precision Prevention - A New Direction in Alzheimer’s Disease

Precision medicine in neurodegeneration: the IHI-PROMINENT project

Protective Alzheimer's disease-associated APP A673T variant predominantly decreases sAPPβ levels in cerebrospinal fluid and 2D/3D cell culture models

Recruitment of pre-dementia participants: main enrollment barriers in a longitudinal amyloid-PET study

Response to “Comment on ‘Dementia prevention: The potential long-term cost-effectiveness of the FINGER prevention program’”

Study design and methods: US study to protect brain health through lifestyle intervention to reduce risk (US POINTER)

Aivoterveyden edistäminen perusterveydenhuollossa vaatii vielä vahvistusta

Antioxidants and Dementia

Association Between Cognition, Health Related Quality of Life, and Costs in a Population at Risk for Cognitive Decline

Associations of Depressive Symptoms and Cognition in the FINGER Trial: A Secondary Analysis of a Randomised Clinical Trial

COVID-19 pandemic and mortality in nursing homes across USA and Europe up to October 2021

Can dementia risk be reduced by following the American Heart Association's Life's Simple 7? A systematic review and dose-response meta-analysis

Can exercise training teach us how to treat Alzheimer’s disease?

Changes in Brain-Health Related Modifiable Risk Factors in Older Adults After One Year of COVID-19-Restrictions

Changes in cognitive functioning after COVID‐19: A systematic review and meta‐analysis

Cognitive Performance at Time of AD Diagnosis: A Clinically Augmented Register-Based Study

Cortisol, cognition and Alzheimer’s disease biomarkers among memory clinic patients

Dementia Risk Scores and Their Role in the Implementation of Risk Reduction Guidelines

Dementia prevention: The potential long-term cost-effectiveness of the FINGER prevention program

Education-Based Cutoffs for Cognitive Screening of Alzheimer’s Disease

Effects of Physical and Cognitive Training on Falls and Concern About Falling in Older Adults: Results From a Randomized Controlled Trial

Experiences of Active Everyday Life Among Persons with Prodromal Alzheimer’s Disease: A Qualitative Study

Experiences of Participation in a Multimodal Preventive Trial MIND-AD MINI Among Persons with Prodromal Alzheimer’s Disease: A Qualitative Study

Factors Predicting Engagement of Older Adults With a Coach-Supported eHealth Intervention Promoting Lifestyle Change and Associations Between Engagement and Changes in Cardiovascular and Dementia Risk: Secondary Analysis of an 18-Month Multinational Randomized Controlled Trial

Liikkumisen kannustimet muistisairauksien riskiryhmään kuuluvilla ikääntyneillä

Mechanisms Underlying Non-Pharmacological Dementia Prevention Strategies: A Translational Perspective

Memory clinic clinicians’ preferences and needs for communication with patients: A multi-national survey study from EU-FINGERS & LETHE projects

Metabolome-wide association study on ABCA7 indicates a role of ceramide metabolism in Alzheimer’s disease

Multidomain interventions for risk reduction and prevention of cognitive decline and dementia: current developments

Multimodal Preventive Trial for Alzheimer’s Disease: MIND-ADmini Pilot Trial Study Design and Progress

New insights into the genetic etiology of Alzheimer’s disease and related dementias

Occupational complexity and cognition in the FINGER multidomain intervention trial

Psychosocial determinants for adherence to a healthy lifestyle and intervention participation in the FINGER trial: an exploratory analysis of a randomised clinical trial

Reducing the Risk of Cognitive Decline and Dementia: WHO Recommendations

Serum Thioredoxin-80 is associated with age, ApoE4, and neuropathological biomarkers in Alzheimer’s disease: a potential early sign of AD

Trajectories of cognitive decline and dementia development: A 12‐year longitudinal study

Trials and Treatments for Vascular Brain Health: Risk Factor Modification and Cognitive Outcomes

β-Amyloid, Tau, Neurodegeneration Classification and Eligibility for Anti-amyloid Treatment in a Memory Clinic Population

27-Hydroxycholesterol, cognition, and brain imaging markers in the FINGER randomized controlled trial

A competing risk joint model for dealing with different types of missing data in an intervention trial in prodromal Alzheimer's disease

Alzheimer's disease

Blood Derived Amyloid Biomarkers for Alzheimer's Disease Prevention

Change in CAIDE Dementia Risk Score and neuroimaging biomarkers during a 2-year multidomain lifestyle randomized controlled trial: results of a post-hoc subgroup analysis

Changes in Lifestyle, Behaviors, and Risk Factors for Cognitive Impairment in Older Persons During the First Wave of the Coronavirus Disease 2019 Pandemic in Finland: Results From the FINGER Study

Common variants in Alzheimer's disease and risk stratification by polygenic risk scores

Dementia research in 2020: moving forward despite the COVID-19 pandemic

Development of the First WHO Guidelines for Risk Reduction of Cognitive Decline and Dementia: Lessons Learned and Future Directions

Digital Screening for Cognitive Impairment - A Proof of Concept Study

Editorial: Cognitive, Psychological, and Psychiatric Consequences of the Coronavirus (COVID-19) Pandemic in the Population of Older Persons With Cognitive Impairment, Dementia, and/or Neuropsychiatric Disorders

Effect of a Multidomain Lifestyle Intervention on Estimated Dementia Risk

Effects of physical and cognitive training on gait speed and cognition in older adults: A randomized controlled trial

Exercise, diet, and cognition in a 4-year randomized controlled trial: Dose-Responses to Exercise Training (DR's EXTRA)

Facilitators and barriers to implementing lifestyle intervention programme to prevent cognitive decline

Health, Lifestyle, and Psycho-Social Determinants of Poor Sleep Quality During the Early Phase of the COVID-19 Pandemic: A Focus on UK Older Adults Deemed Clinically Extremely Vulnerable

How can dementia and disability be prevented in older adults: Where are we today and where are we going?

Impact of the COVID-19 pandemic on statistical design and analysis plans for multidomain intervention clinical trials: Experience from World-Wide FINGERS

Muistisairaudet

Multidomain interventions: state-of-the-art and future directions for protocols to implement precision dementia risk reduction. A user manual for Brain Health Services-part 4 of 6

Personal Social Networks of Community-Dwelling Oldest Old During the Covid-19 Pandemic - A Qualitative Study

Quantifying dementia prevention potential in the FINGER randomized controlled trial using the LIBRA prevention index.

Red Cell Distribution Width and Dementia Among Rural-Dwelling Older Adults: The MIND-China Study

Research diagnostic criteria for Alzheimer's disease: findings from the LipiDiDiet randomized controlled trial

Serum proBDNF Is Associated With Changes in the Ketone Body ß-Hydroxybutyrate and Shows Superior Repeatability Over Mature BDNF: Secondary Outcomes From a Cross-Over Trial in Healthy Older Adults

Sex and gender differences in genetic and lifestyle risk and protective factors for dementia

Sex differences in dementia and response to a lifestyle intervention: Evidence from Nordic population-based studies and a prevention trial

Telomere length change in a multidomain lifestyle intervention to prevent cognitive decline: a randomized clinical trial