Reetta Kälviäinen
Professori
Neurologian oppiaineesta vastaava professori Itä-Suomen yliopisto
Epilepsiakeskuksen johtaja, KYS, Euroopan harvinaissairausosaamiskeskusverkoston EpiCARE jäsen
Kansallisen Neurokeskuksen johtoryhmän puheenjohtaja
Lääketieteen laitos, Kliinisen lääketieteen yksikkö
reetta.kalviainen@uef.fi | 040 583 9249
0405839249
040 5839249
040 583 9249
+358 40 583 9249
+35840 583 9249
040 5839 249
+358 40 5839 249
+35840 5839 249
+358 40 5839249
+35840 5839249
+358405839249
040 5839249
040 583 9249
+358 40 583 9249
+35840 583 9249
040 5839 249
+358 40 5839 249
+35840 5839 249
+358 40 5839249
+35840 5839249
+358405839249
Tutkimusryhmät
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Aivotutkimusyksikkö 01.01.2022 - -
Clinical Epilepsy Research 01.01.2010 - -
Intracranial Aneurysm Group 01.01.2022 - -
Kliininen tutkimuskeskus (KTK) 01.01.2002 -
Projektit
Julkaisut
226 kappaletta-
Impact of drug treatment and drug interactions in post-stroke epilepsy
Zhao, Lanqing; Li, Jinwei; Kälviäinen, Reetta; Jolkkonen, Jukka; Zhao, Chuansheng. Pharmacology and therapeutics [In press, corrected proof]: 108030. 2022 -
A systems-level analysis highlights microglial activation as a modifying factor in common epilepsies
Altmann, A; Ryten, M; Di Nunzio, M; Ravizza, T; Tolomeo, D; Reynolds, RH; Somani, A; Bacigaluppi, M; Iori, V; Micotti, E; Di Sapia, R; Cerovic, M; Palma, E; Ruffolo, G; Botía, JA; Absil, J; Alhusaini, S; Alvim, MKM; Auvinen, P; Bargallo, N; et al. [Incl. Kälviäinen, R]. Neuropathology and applied neurobiology 2022; 48 1: e12758. 2021 -
A survey of the European Reference Network EpiCARE on clinical practice for selected rare epilepsies
Baumgartner, Tobias; Carreño, Mar; Rocamora, Rodrigo; Bisulli, Francesca; Boni, Antonella; Brázdil, Milan; Horak, Ondrej; Craiu, Dana; Pereira, Cristina; Guerrini, Renzo; San Antonio-Arce, Victoria; Schulze-Bonhage, Andreas; Zuberi, Sameer M; Hallböök, Tove; Kalviainen, Reetta; Lagae, Lieven; Nguyen, Sylvie; Quintas, Sofia; Franco, Ana; Cross, J Helen et al.. Epilepsia open 6 1: 160-170. 2021 -
Sub-genic intolerance, ClinVar, and the epilepsies: A whole-exome sequencing study of 29,165 individuals
Epi25 Collaborative [incl. Kälviäinen, Reetta; Timonen, Oskari]. American journal of human genetics 108 6: 965-982. 2021 -
Epilepsia
Kälviäinen, Reetta; Pesonen, Tuula, Äikiä, Marja / Kliininen neuropsykiatria (2. uudistettu painos). 2021. 2021 -
Artificial intelligence for classification of temporal lobe epilepsy with ROI-level MRI data: A worldwide ENIGMA-Epilepsy study
Gleichgerrcht, E; Munsell, BC; Alhusaini, S; Alvim, MKM; Bargalló, N; Bender, B; Bernasconi, A; Bernasconi, N; Bernhardt, B; Blackmon, K; Caligiuri, ME; Cendes, F; Concha, L; Desmond, PM; Devinsky, O; Doherty, CP; Domin, M; Duncan, JS; Focke, NK; Gambardella, A; et al; [incl. Kälviäinen, R]. Neuroimage. clinical 31: 102765. 2021 -
Epilepsian leikkaushoito
Jutila, Leena; Kälviäinen, Reetta; Miettinen, Riia; Immonen, Arto. Pinsetti 33 1: 14-19. 2021 -
Exome sequencing reveals predominantly de novo variants in disorders with intellectual disability (ID) in the founder population of Finland
Järvelä, Irma; Määttä, Tuomo; Acharya, Anushree; Leppälä, Juha; Jhangiani, Shalini N; Arvio, Maria; Siren, Auli; Kankuri-Tammilehto, Minna; Kokkonen, Hannaleena; Palomäki, Maarit; Varilo, Teppo; Fang, Mary; Hadley, Trevor D; Jolly, Angad; Linnankivi, Tarja; Paetau, Ritva; Saarela, Anni; Kälviäinen, Reetta; Olme, Jan; Nouel-Saied, Liz M et al.. Human genetics 140 7: 1011-1029. 2021 -
Distinct gene-set burden patterns underlie common generalized and focal epilepsies
Koko, Mahmoud; Krause, Roland; Sander, Thomas; Bobbili, Dheeraj Reddy; Nothnagel, Michael; May, Patrick; Lerche, Holger; Epi25 Collaborative [incl. Kälviäinen, Reetta; Auvinen, Pia; Saarela, Anni]. EBioMedicine 72: 103588. 2021 -
Jaettu päätöksenteko epilepsian hoidossa
Kuusisto, Hanna; Kälviäinen, Reetta; Jylhä, Virpi; Saranto, Kaija. EPILEPSIA-LEHTI 52 3: 12 - 13. 2021 -
Wearable monitoring of positive and negative myoclonus in progressive myoclonic epilepsy type 1
Rissanen, Saara M; Hyppönen, Jelena; Silvennoinen, Katri; Säisänen, Laura; Karjalainen, Pasi A; Mervaala, Esa; Kälviäinen, Reetta. Clinical neurophysiology 132 10: 2464-2472. 2021 -
Status epilepticus: Practice variation and adherence to treatment guideline in a large community hospital
Sairanen, Joni J; Kantanen, Anne-Mari; Hyppölä, Harri T; Kälviäinen, Reetta K. Journal of the neurological sciences 427: 117542. 2021 -
Adult-Onset Epilepsy Incidence in Finland over 34 Years: a nationwide registry-study
Sipilä, Jussi OT; Kälviäinen, Reetta. European journal of neurology 2022; 29 2: 605-608. 2021 -
Unverricht-Lundborgin taudin epidemiologia Suomessa
Sipilä, Jussi; Kälviäinen, Reetta. Duodecim 137 11: 1125 - 1126. 2021 -
Atlas of lesion locations and postsurgical seizure freedom in focal cortical dysplasia: A MELD study
Wagstyl, Konrad; Whitaker, Kirstie; Raznahan, Armin; Seidlitz, Jakob; Vértes, Petra E.; Foldes, Stephen; Humphreys, Zachary; Hu, Wenhan; Mo, Jiajie; Likeman, Marcus; Davies, Shirin; Lenge, Matteo; Cohen, Nathan T.; Tang, Yingying; Wang, Shan; Ripart, Mathilde; Chari, Aswin; Tisdall, Martin; Bargallo, Nuria; Conde-Blanco, Estefanía; et al. [Incl. Liu, Yawu; Kälviäinen, Reetta]. Epilepsia 2022; 63 1: 61-74. 2021 -
Cognitive functioning in progressive myoclonus epilepsy type 1 (Unverricht-Lundborg Disease, EPM1)
Äikiä, Marja; Hyppönen, Jelena; Mervaala, Esa; Kälviäinen, Reetta. Epilepsy and behavior 122: 108157. 2021 -
Epilepsy and cannabidiol: a guide to treatment
Arzimanoglou, Alexis; Brandl, Ulrich; Cross, Helen J; Gil-Nagel, Antonio; Lagae, Lieven; Johannessen Landmark, Cecilie ; Specchio, Nicola; Nabbout, Rima; Thiele, Elizabeth A; Gubbay, Oliver; The Cannabinoids International Experts Panel, Collaborators [Incl. Kälviäinen, Reetta]. Epileptic disorders 22 1: 1-14. 2020 -
Epilepsiat (aikuiset)
Kälviäinen, Reetta; Ansakorpi, Hanna; Immonen, Arto; Keränen, Tapani; Komulainen, Jorma; Komulainen, Sanna; Lamusuo, Salla; Peltola, Jukka / Käypä hoito -suositus. 2020. 2020 -
Automatic assessment of the myoclonus severity from videos recorded according to standardized Unified Myoclonus Rating Scale protocol and using human pose and body movement analysis
Hyppönen, J; Hakala, A; Annala, K; Zhang, H; Peltola, J; Mervaala, E; Kälviäinen, R. Seizure: european journal of epilepsy 76: 72-78. 2020 -
Epilepsian digihoitopolku auttaa saaman yhteyden hoitopaikkaan silloin kun on tarve
Kälviäinen, Reetta. EPILEPSIA-LEHTI 51 4: 4-5. 2020 -
Etävastaanottoihin vauhtia koronakeväänä
Kälviäinen, Reetta. EPILEPSIA-LEHTI 51 4: 6-7. 2020 -
Lääkkeiden saatavuushäiriöt ovat lisääntyneet merkittävästi
Kälviäinen, Reetta. EPILEPSIA-LEHTI 51 1: 17-18. 2020 -
Seizure outcome and use of antiepileptic drugs after epilepsy surgery according to histopathological diagnosis
Lamberink, Herm J; Otte, Willem M; Blümcke, Ingmar; Braun Kees P J; Aronica, Eleonora; Coras, Roland; Blumcke, Ingmar; Hamer, Hajo; Rössler, Karl; Bien, Christian G; Cloppenborg, Thomas; Grote, Alexander; Schramm, Johannes; Becker, Albert; Elger, Christian; Duncan, John S; De Tisi, Jane; Thom, Maria; Chassoux, Francine; Devaux, Bertrand [incl. Kälviäinen, Reetta]. The Lancet Neurology 19 9: 748-757. 2020 -
Network-based atrophy modeling in the common epilepsies: A worldwide ENIGMA study
Larivière, Sara; Rodríguez-Cruces, Raúl; Royer, Jessica; Caligiuri, Maria Eugenia; Gambardella, Antonio; Concha, Luis; Keller, Simon S; Cendes, Fernando; Yasuda, Clarissa; Bonilha, Leonardo; Gleichgerrcht, Ezequiel; Focke, Niels K; Domin, Martin; von Podewills, Felix; Langner, Soenke; Rummel, Christian; Wiest, Roland; Martin, Pascal; Kotikalapudi, Raviteja; O'Brien, Terence J; et al. [incl. Kälviä. Science advances 6 47: eabc6457. 2020 -
Progressive Myoclonic Epilepsy Type 1: 2004 Jun 24 [Updated 2020 Jul 2]
Lehesjoki, Anna-Elina; Kälviäinen, Reetta. Genereviews [Updated 2020 Jul 2]: 1-16. 2020 -
The role of polygenic risk and susceptibility genes in breast cancer over the course of life
Mars, Nina; Widén, Elisabeth; Kerminen, Sini; Meretoja, Tuomo; Pirinen, Matti; Parolo, Pietro della Briotta; Palta, Priit; FinnGen, Palotie, Aarno; Kaprio, Jaakko; Joensuu, Heikki; Daly, Mark; Ripatti, Samuli [incl. Hiltunen, Mikko; Heikkinen, Sami; Julkunen, Valtteri; Kosma, Veli-Matti; Mannermaa, Arto; Kälviäinen, Reetta]. Nature communications 11 1: 6383. 2020 -
Epilepsy subtype-specific copy number burden observed in a genome-wide study of 17 458 subjects
Niestroj, Lisa-Marie; Perez-Palma, Eduardo; Howrigan, Daniel P; Zhou, Yadi; Cheng, Feixiong; Saarentaus, Elmo; Nürnberg, Peter; Stevelink, Remi; Daly, Mark J; Palotie, Aarno; Lal, Dennis; Epi25 Collaborative (incl. Kälviäinen, Reetta; Auvinen, Pia; Saarela, Anni). Brain 143 7: 2106-2118. 2020 -
Impact of diagnostic delay on seizure outcome in newly diagnosed focal epilepsy
Parviainen, Laura; Kälviäinen, Reetta; Jutila, Leena. Epilepsia open 5 4: 605.610. 2020 -
Focal nonmotor versus motor seizures: The impact on diagnostic delay in focal epilepsy
Pellinen, Jacob; Tafuro, Erica; Yang, Annie; Price, Dana; Friedman, Daniel; Holmes, Manisha; Barnard, Sarah; Detyniecki, Kamil; Hegde, Manu; Hixson, John; Haut, Sheryl; Kälviäinen, Reetta; French, Jacqueline. Epilepsia 61 2643-2652: 1-10. 2020 -
Cognitive functioning in new-onset juvenile myoclonic epilepsy
Raatikainen, M; Kälviäinen, R; Jutila, L; Äikiä, M. Epilepsy and behavior 106: 107015. 2020 -
Lacosamide in Patients With Epilepsy of Cerebrovascular Etiology
Rosenow, Felix; Brandt, Christian; Bozorg, Ali; Dimova, Svetlana; Steiniger-Brach, Björn; Zhang, Ying; Ferrò, Bruno; Holmes, Gregory; Kälviäinen, Reetta. Acta neurologica scandinavica 141 6: 473-482. 2020 -
Outcome of status epilepticus and the predictive value of the EMSE and STESS scores: A prospective study
Sairanen, JJ; Kantanen, AM; Hyppölä, HT; Kälviäinen, RK. Seizure: european journal of epilepsy 75: 115-120. 2020 -
Analysis of shared common genetic risk between amyotrophic lateral sclerosis and epilepsy
Schijven, Dick; Stevelink, Remi; McCormack, Mark; van Rheenen, Wouter; Luykx, Jurjen J; Koeleman, Bobby PC; Veldink, Jan H; Project MinE ALS GWAS Consortium; International League Against Epilepsy Consortium on Complex Epilepsies [incl. Kälviäinen, Reetta]. Neurobiology of aging 92: 153.e1-153.e5. 2020 -
Unverricht-Lundborg disease (EPM1) in Finland: A nationwide population-based study
Sipilä, Jussi O T; Hyppönen, Jelena; Kytö, Ville; Kälviäinen, Reetta. Neurology 95 23: e3117-e3123. 2020 -
The ENIGMA-Epilepsy working group: Mapping disease from large data sets
Sisodiya, Sanjay M; Whelan, Christopher D; Hatton, Sean N; Huynh, Khoa; Altmann, Andre; Ryten, Mina; Vezzani, Annamaria; Caligiuri, Maria Eugenia; Labate, Angelo; Gambardella, Antonio; Ives-Deliperi, Victoria; Meletti, Stefano; Munsell, Brent C; Bonilha, Leonardo; Tondelli, Manuela; Rebsamen, Michael; Rummel, Christian; Vaudano, Anna Elisabetta; Wiest, Roland; Balachandra, Akshara R et al. [incl. . Human brain mapping [Online ahead of print 29 May 2020]: 1-16. 2020 -
Harvinaisepilepsiat - mistä on kyse?
Vaikean epilepsian kansallinen koordinaatioryhmä; Kälviäinen, Reetta. EPILEPSIA-LEHTI 5: 8-11. 2020 -
Standardized Brain MRI Acquisition Protocols Improve StatisticalPower in Multicenter Quantitative Morphometry Studies
George, Allan; Kuzniecky, Ruben; Rusinek, Henry; Pardoe, Heath R.; French, Jacqueline; Lowenstein, Daniel; Cristofaro, Sabrina; McKenna, Kevin; Mays, Vickie; Shack, Darrell; Barnard, Sarah; Burke, Cheryl; Hegde, Manu; Glauser, Tracy; O'Brien, Terence; Pollard, John; Ting, Tricia; Meador, Kimford; Darby, David; Morrison, Chris et al (Incl Kälviäinen, Reetta). Journal of neuroimaging 2020; 30 1: 126-133. 2019 -
Incidence of the different stages of status epilepticus in Eastern Finland: A population-based study
Kantanen, Anne-Mari; Sairanen, Joi; Kälviäinen, Reetta. Epilepsy and behavior 101 Part B: 106413. 2019 -
Epielpsian Käypä hoito -suositukset on päivitetty
Kälviäinen, Reetta. EPILEPSIA-LEHTI 50 5: 9-10. 2019 -
Epilepsian hoidon kehitys
Kälviäinen, Reetta. EPILEPSIA-LEHTI 50 4: 5-6. 2019 -
Management of prolonged epileptic seizures and status epilepticus in palliative care patients
Kälviäinen, Reetta; Reinikainen, Matti. Epilepsy and behavior 101 Part B: 106288. 2019 -
Polygenic burden in focal and generalized epilepsies
Leu, Costin; Stevelink, Remi; Smith, Alexander W; Goleva, Slavina B; Kanai, Masahiro; Ferguson, Lisa; Campbell, Ciaran; Kamatani, Yoichiro; Okada, Yukinori; Sisodiya, Sanjay M; Cavalleri, Gianpiero L; Koeleman, Bobby PC; Lerche, Holger; Jehi, Lara; Davis, Lea K; Najm, Imad M; Palotie, Aarno; Epi25 Consortium (incl. Kälviäinen, Reetta; Auvinen, Pia; Saarela, Anni). Brain 142 11: 3473-3481. 2019 -
Treatment delay in status epilepticus - more effective prehospital symptom recognition warranted
Sairanen, JJ; Kantanen, AM; Hyppölä, HT; Kälviäinen, RK. Scandinavian journal of trauma, resuscitation and emergency medicine 27: 28. 2019 -
Assessing the genetic association between vitamin B6 metabolism and genetic generalized epilepsy
Stevelink, Remi; Pangilinan, Faith; Jansen, Floor E; Braun, Kees PJ; Molloy, Anne M; Brody, Lawrence C; Koeleman, Bobby PC; International League Against Epilepsy Consortium on Complex Epilepsies [Incl. Kälviäinen, Reetta]. Molecular genetics and metabolism reports 21: 100518. 2019 -
Perampanel for treatment of status epilepticus in Austria, Finland, Germany and Spain
Strzelczyk, A; Knake, S; Kälviäinen, R; Santamarina, E; Toledo, M; Willig, S; Rohracher, A; Trinka, E; Rosenow, F. Acta neurologica scandinavica 139 4: 369-376. 2019 -
Genetic architecture of human plasma lipidome and its link to cardiovascular disease
Tabassum, Rubina; Ramo, Joel T; Ripatti, Pietari; Koskela, Jukka T; Kurki, Mitja; Karjalainen, Juha; Palta, Priit; Hassan, Shabbeer; Nunez-Fontarnau, Javier; Kiiskinen, Tuomo T J; Söderlund, Sanni; Matikainen, Niina; Gerl, Mathias J; Surma, Michal A; Klose, Christian; Stitziel, Nathan O; Laivuori, Hannele; Havulinna, Aki S; Service, Susan K; Salomaa, Veikko et al. (Incl Mannermaa, Arto; Heikkinen,. Nature communications 10: 4329. 2019 -
Declining malformation rates with changed antiepileptic drug prescribing: An observational study
Tomson, Torbjörn; Battino, Dina; Bonizzon,i Erminio; Craig, John; Lindhout, Dick; Perucca, Emilio; Sabers, Anne; Thomas, Sanjeev V; Vajda Frank; for The EURAP Study Group [incl. Kälviäinen, R]. Neurology 93 9: e831-e840. 2019 -
Economic Value of Adjunctive Brivaracetam Treatment Strategy for Focal Onset Seizures in Finland
Väätäinen, S; Soini, E; Peltola, J; Charokopou, M; Taiha, M; Kälviäinen, R. Advances in therapy 2020; 37 1: 477-500. 2019 -
The provision of epilepsy care across Europe 2017: A 17-year follow-up survey
Zelano, Johan; Klecki, Judith; Christensen, Jakob; Tomson, Torbjörn; Malmgren, Kristina; The ESBACE consortium Collaborators (incl. Kälviäinen, Reetta). Epilepsia open 4 1: 144-152. 2019 -
Analysis of shared heritability in common disorders of the brain
Anttila, V; Bulik-Sullivan, B; Finucane, HK; Walters, RK; Bras, J; Duncan, L; Escott-Price, V; Falcone, GJ; Gormley, P; Malik, R; Patsopoulos, NA; Ripke, S; Wei, Z; Yu, D; Lee, PH; Turley, P; Grenier-Boley, B; Chouraki, V; Kamatani, Y; Berr, C; et al [Incl Kälviäinen, Reetta]. Science 360 6395: eaap8757. 2018 -
European trends in epilepsy surgery
Baud, Maxime O; Perneger, Thomas; Racz, Attila; Pensel, Max C; Elger, Christian; Rydenhag, Bertil; Malmgren, Kristina; Cross, J Helen; McKenna, Grainne; Tisdall, Martin; Lamberink, Herm J; Rheims, Sylvain; Ryvlin, Philippe; Isnard, Jean; Mauguiere, Francois; Arzimanoglou, Alexis; Akkol, Serdar; Deniz, Kaancan; Ozkara, Cigdem; Lossius, Morten et al. [Incl Kälviäinen, Reetta]. NEUROLOGY 91 2: E96-E106. 2018 -
Etiologies and characteristics of refractory status epilepticus cases in different areas of the world: Results from a global audit
Ferlisi, M; Hocker, S; Trinka, E; Shorvon, S; International Steering Committee of the StEp Audit (incl. Singh, G; Kälviäinen, R; Kramer, U; Godoy, D; Newton, C; O'Brien, T; Cook, M; Rossetti, A; Groppa, S; Kumlien, E; Ercegovac, M; Yasiry, Z; Guecht, A; Wu, T; Nabbout, R; Tripathi, M; et al.). Epilepsia 59 S2: 100-107. 2018 -
No Evidence of a Causal Role of Antiepileptic Drug Treatment with Regard to the Development of Dementia
Helmstaedter, Christoph; Beghi, Ettore; Elger, Christian E; Kälviäinen, Reetta; Malmgren, Kristina; May, Theodor W; Perucca, Emilio; Trinka, Euden; Witt, Juri-Alexander. Journal of the american geriatrics society 66 9: 1850-1852. 2018 -
No proof of a causal relationship between antiepileptic drug treatment and incidence of dementia. Comment on: Use of antiepileptic drugs and dementia risk - An analysis of Finnish health register and German health insurance data
Helmstaedter, Christoph; Beghi, Ettore; Elger, Christian E; Kälviäinen, Reetta; Malmgren, Kristina; May, Theodor W; Perucca, Emilio; Trinka, Euden; Witt, Juri-Alexander. Epilepsia 59 7: 1303-1306. 2018 -
Variants p.Q1236H and p.E1143G in mitochondrial DNA polymerase gamma POLG1 are not associated with increased risk for valproate-induced hepatotoxicity or pancreatic toxicity: A retrospective cohort study of patients with epilepsy
Hynynen, J; Pokka, T; Komulainen-Ebrahim, J; Myllynen, P; Kärppä, M; Pylvänen, L; Kälviäinen, R; Sokka, A; Jyrkilä, A; Lähdetie, J; Haataja, L; Mäkitalo, A; Ylikotila, P; Eriksson, K; Haapala, P; Ansakorpi, H; Hinttala, R; Vieira, P; Majamaa, K; Rantala, H; et al. Epilepsia 59 11: 2125-2136. 2018 -
Abnormal motor cortical adaptation to external stimulus in Unverricht-Lundborg disease (progressive myoclonus type 1, EPM1)
Julkunen, Petro; Löfberg, Olli; Kallioniemi, Elisa; Hyppönen, Jelena; Kälviäinen, Reetta; Mervaala, Esa. JOURNAL OF NEUROPHYSIOLOGY 120 2: 617-623. 2018 -
Reducing valproate use in women with epilepsy
Kälviäinen, Reetta; Straus, Sabine; Dogne, Jean-Michel; Bakchine, Serge; Haas, Manuel. The Lancet Neurology 17 7: 580-581. 2018 -
Comparable indicators of therapeutic misconception between epilepsy or Parkinson's disease patients between those with clinical trial experience and trial non-participants.
Reijula, Emmi; Halkoaho, Arja; Pietilä, Anna-Maija; Selander, Tuomas; Martikainen, Kirsti; Kälviäinen, Reetta; Keränen, Tapani. SEIZURE 60: 61-67. 2018 -
Antiepileptic drug treatment of generalized tonic-clonic seizures: An evaluation of regulatory data and five criteria for drug selection
Shorvon, SD; Bermejo, PE; Gibbs, AA; Huberfeld, G; Kälviäinen, R. EPILEPSY & BEHAVIOR 82: 91-103. 2018 -
Genome-wide mega-analysis identifies 16 loci and highlights diverse biological mechanisms in the common epilepsies
The International League Against Epilepsy Consortium on Complex Epilepsies; [Incl. Kälviäinen, Reetta]. Nature Communications 9: 5269. 2018 -
Comparative risk of major congenital malformations with eight different antiepileptic drugs: a prospective cohort study of the EURAP registry
Tomson, T; Battino, D; Bonizzoni, E; Craig, J; Lindhout, D; Perucca, E; Sabers, A; Thomas, SV; Vajda, F; Faravelli, F; Pantaleoni, C; Robert-Gnansia, E; Cabral-Lim, L; Cebular, B; De Marinis, A; Kälviäinen, R; Khomeriki, K; Kiteva-Trencevska, G; Kochen, S; EURAP Study Group; et al.(incl. Kälviäinen Reetta). The Lancet Neurology 17 6: 530-538. 2018 -
Declining trend in valproate use in Finland among childbearing-aged females in 2012-2016 - a nationwide registry-based outpatient study
Virta, LJ; Kälviäinen, R; Villikka, K; Keränen, T. EUROPEAN JOURNAL OF NEUROLOGY 25 6: 869-874. 2018 -
Structural brain abnormalities in the common epilepsies assessed in a worldwide ENIGMA study
Whelan, CD; Altmann, A; Botía, JA; Jahanshad, N; Hibar, DP; Absil, J; Alhusaini, S; Alvim, MKM; Auvinen, P; Bartolini, E; Bergo, FPG; Bernardes, T; Blackmon, K; Braga, B; Caligiuri, ME; Calvo, A; Carr, SJ; Chen, J; Chen, S; Cherubini, A; et al [Incl. Kälviäinen, R]. BRAIN [ONLINE] 141 2: 391-408. 2018 -
Co-morbidity and clinically significant interactions between antiepileptic drugs and other drugs in elderly patients with newly diagnosed epilepsy
Bruun Emmi, Virta Lauri J, Kälviäinen Reetta, Keränen Tapani. EPILEPSY & BEHAVIOR 73: 71-76. 2017 -
Early Intervention : Bridging the Early Diagnosis and Treatment Gap - a policy white paper towards optimizing research and care for brain disorders
Mohr P, Ieven A, Arteel P, Winkler P, La Park A, Boyer P, Galderisi S, Karkkainen H, Wasserman D, Gaebel W,Jaarsma J, Dauvilliers Y, Ferri R, Rijsman R, Sakkas GK, Trenkwalder C, Oertel W, Ahmerkamp-Böhme J, Petersen G, Deuschl G, Michler F et al (incl. Kälviäinen R, Martikainen J). 2017 2017 -
European Stroke Organisation guidelines for the management of post-stroke seizures and epilepsy
Holtkamp Martin, Beghi Ettore, Benninger Felix, Kälviäinen Reetta, Rocamora Rodrigo, Christensen Hanne. European Stroke Journal 2 2: 103-115. 2017 -
Epilepsy-associated long-term mortality after aneurysmal subarachnoid hemorrhage
Huttunen J, Lindgren A, Kurki MI, Huttunen T, Frösen J, Koivisto T, von und zu Fraunberg M, Immonen A, Jääskeläinen JE, Kälviäinen R. NEUROLOGY 89 3: 263-268. 2017 -
Predictors of hospital and one-year mortality in intensive care patients with refractory status epilepticus: a population-based study
Kantanen A-M, Kälviäinen R, Parviainen I, Ala-Peijari M, Bäcklund T, Koskenkari J, Laitio R, Reinikainen M. CRITICAL CARE (ONLINE) 21 1: 1-7. 2017 -
Long-term outcome of refractory status epilepticus in adults: A retrospective population-based study
Kantanen A-M, Reinikainen M, Parviainen I, Kälviäinen R. EPILEPSY RESEARCH 133: 13-21. 2017 -
TMS combined with EEG in Genetic Generalized Epilepsy: A phase II diagnostic accuracy study
Kimiskidis Vasilios K, Tsimpiris Alkiviadis, Ryvlin Philippe, Kalviainen Reetta, Koutroumanidis Michalis, Valentin Antonio, Laskaris Nikolaos, Kugiumtzis Dimitris. CLINICAL NEUROPHYSIOLOGY 128 2: 367-381. 2017 -
Cost savings and improved patient outcomes from best management of epilepsy
Marson AG, Bolan A, Mahon J, Little A, Dickson R, Boon P, Depondt C, Martikainen J, Ryvlin P, Kälviäinen R. Teoksessa: Nutt D, Boyer P, Di luca M, Oertel W (toim.) The value of treatment for brain disorders. EBC Research Project. s. 105-109. 2017 -
Hippocampal Sclerosis and Epilepsy in Elderly Population
Rauramaa Tuomas, Solomon Alina, Pikkarainen Maria, Kälviäinen Reetta, Alafuzoff Irina. Journal of Alzheimers Disease & Parkinsonism 7 5: 384. 2017 -
Clinical features of Parkinson's disease patients are associated with therapeutic misconception and willingness to participate in clinical trials
Reijula E, Pietilä AM, Halkoaho A, Selander T, Martikainen K, Kälviäinen R, Keränen T. TRIALS [ONLINE] 18 1: 444. 2017 -
Seizure - European Journal of Epilepsy at age 25: Where are we now and where we are going?
Reuber Markus, Kälviänen Reetta. SEIZURE 44: 1-3. 2017 -
Etiology, syndrome diagnosis, and cognition in childhood-onset epilepsy: A population-based study
Sokka Arja, Olsen Päivi, Kirjavainen Jarkko, Harju Maijakaisa, Keski-Nisula Leea, Räisänen Sari, Heinonen Seppo, Kälviäinen Reetta. Epilepsia Open 2 1: 76-83. 2017 -
The value of treatment for brain disorders
Quoidbach V, Esposito G, Destrebecq F, Kramer S, Tinelli M, Knapp M, Guldemond N, Dodel R, Gaebel W, Kälviäinen R, Kehler U, Mitsikostas D, Sørensen PS, Trenkwalder C, Vanhooren G, Visser PJ. 2017 2017 -
Current standards of neuropsychological assessment in epilepsy surgery centers across Europe
Vogt VL, Äikiä M, del Barrio A, Boon P, Borbély C, Bran E, Braun K, Carette E, Clark M, Cross JH, Dimova P, Fabo D, Foroglou N, Francione S, Gersamia A, Gil-Nagel A, Guekht A, Harrison S, Hecimovic H, Heminghyt E et al. EPILEPSIA (NY) 58 3: 343-355. 2017 -
Outcome of initial antiepileptic drug treatment in elderly patients with newly diagnosed epilepsy
Bruun Emmi, Kälviäinen Reetta, Keränen Tapani. EPILEPSY RESEARCH 127: 60-65. 2016 -
Unverricht-Lundborg disease
Crespel Arielle, Ferlazzo Edoardo, Franceschetti Silvana, Genton Pierre, Gouider Riadh, Kälviäinen Reetta, Korja Miikka, Lehtinen Maria K, Mervaala Esa, Simonato Michele, Vaarmann Annika. EPILEPTIC DISORDERS 18 Suppl. 2: S28-S37. 2016 -
Antidepressant Use After Aneurysmal Subarachnoid Hemorrhage: A Population-Based Case-Control Study
Huttunen Jukka, Lindgren Antti, Kurki Mitja I, Huttunen Terhi, Frösen Juhana, von und zu Fraunberg Mikael, Koivisto Timo, Kälviäinen Reetta, Räikkönen Katri, Viinamäki Heimo, Jääskeläinen Juha E, Immonen Arto. STROKE 47 9: 2242-8. 2016 -
Testing of triggers by data mining of epilepsy patients' structured nursing records
Kinnunen Ulla-Mari, Kivekäs Eija, Paananen Pekka, Kälviäinen Reetta, Saranto Kaija. Teoksessa: Walter Sermeus, Paula M. Procter, Patrick Weber (toim.) Nursing Informatics 2016. Ios press. Studies in Health Technology and Informatics 225. s. 461-465. 2016 -
Functionality of Triggers for Epilepsy Patients Assessed by Text and Data Mining of Medical and Nursing Records
Kivekäs Eija, Kinnunen Ulla-Mari, Paananen Pekka, Kälviäinen Reetta, Haatainen Kaisa, Saranto Kaija. Teoksessa: Sermeus Walter, Procter Paula M, Weber Patrick (toim.) Nursing Informatics 2016. Ios press. Studies in Health Technology and InformaticsY 225. s. 128-132. 2016 -
Current practices in long-term video-EEG monitoring services: A survey among partners of the E-PILEPSY pilot network of reference for refractory epilepsy and epilepsy surgery
Kobulashvili T, Höfler J, Dobesberger J, Ernst F, Ryvlin P, Cross JH, Braun K, Dimova P, Francione S, Hecimovic H, Helmstaedter C, Kimiskidis VK, Lossius MI, Malmgren K, Marusic P, Steinhoff BJ, Boon P, Craiu D, Delanty N, Fabo D et al. SEIZURE 38: 38-45. 2016 -
Myoclonus and seizures in progressive myoclonus epilepsies: pharmacology and therapeutic trials
Michelucci Roberto, Pasini Elena, Riguzzi Patrizia, Andermann Eva, Kälviäinen Reetta, Genton Pierre. EPILEPTIC DISORDERS 18 S2: S145-S153. 2016 -
Current use of imaging and electromagnetic source localization procedures in epilepsy surgery centers across Europe
Mouthaan BE, Rados M, Barsi P, Boon P, Carmichael DW, Carrette E, Craiu D, Cross JH, Diehl B, Dimova P, Fabo D, Francione S, Gaskin V, Gil-Nagel A, Grigoreva E, Guekht A, Hirsch E, Hecimovic H, Helmstaedter C, Jung et al, E-PILEPSY consortium (incl. Kälviäinen R). EPILEPSIA (NY) 57 5: 770-776. 2016 -
The future of medicine will be dark without international collaboration
Reuber M, Helmstaedter C, Liao W, Loddenkemper T, Thomas R, Kälviäinen R, Mann M. SEIZURE 41 42: 1. 2016 -
25 years of advances in the definition, classification and treatment of status epilepticus
Trinka Eugen, Kälviäinen Reetta. SEIZURE 2017; 44: 65-73. 2016 -
Epilepsy priorities in Europe: A report of the ILAE-IBE Epilepsy Advocacy Europe Task Force
Baulac Michel, de Boer Hanneke, Elger Christian, Glynn Mike, Kälviäinen Reetta, Little Ann, Mifsud Janet, Perucca Emilio, Pitkänen Asla, Ryvlin Philippe. EPILEPSIA (NY) [epub ahead of print 28 SEP 2015]: -. 2015 -
Choice of the first anti-epileptic drug in elderly patients with newly diagnosed epilepsy: A Finnish retrospective study
Bruun Emmi, Virta Lauri J, Kälviäinen Reetta, Keränen Tapani. SEIZURE 31: 27-32. 2015 -
Preliminary results of the global audit of treatment of refractory status epilepticus
Ferlisi M, Hocker S, Grade M, Trinka E, Shorvon S on behalf of the International Steering Committee of the StEp Audit (incl. Reetta Kälviäinen). EPILEPSY & BEHAVIOR 49: 318-324. 2015 -
Epilepsy after aneurysmal subarachnoid hemorrhage: A population-based, long-term follow-up study
Huttunen Jukka, Kurki Mitja I, von und zu Fraunberg Mikael, Koivisto Timo, Ronkainen Antti, Rinne Jaakko, Jääskeläinen Juha E, Kälviäinen Reetta, Immonen Arto. NEUROLOGY 84 22: 2229-37. 2015 -
Refining the phenotype of Unverricht-Lundborg disease (EPM1): a population-wide Finnish study
Hyppönen Jelena, Äikiä Marja, Joensuu Tarja, Julkunen Petro, Danner Nils, Koskenkorva Päivi, Vanninen Ritva, Lehesjoki Anna-Elina, Mervaala Esa, Kälviäinen Reetta. NEUROLOGY 84 15: 1529-1536. 2015 -
Incidence and mortality of super-refractory status epilepticus in adults
Kantanen Anne-Mari, Reinikainen Matti, Parviainen Ilkka, Ruokonen Esko, Ala-Peijari Marika, Bäcklund Tom, Koskenkari Juha, Laitio Ruut, Kälviäinen Reetta. EPILEPSY & BEHAVIOR 49: 131-134. 2015 -
Transcranial Magnetic Stimulation Combined with EEG Reveals Covert States of Elevated Excitability in the Human Epileptic Brain
Kimiskidis Vasilios K, Koutlis Christos, Tsimpiris Alkiviadis, Kälviäinen Reetta, Ryvlin Philippe, Kugiumtzis Dimitris. International Journal of Neural Systems 25 5: 20 pages. 2015 -
Trigger Development for the Improvement of Neurological Patient Care
Kivekäs Eija, Kinnunen Ulla-Mari, Haatainen Kaisa, Kälviäinen Reetta, Saranto Kaija. Teoksessa: Indra Neil Sarkar, Andrew Georgiou, Paulo Mazzoncini de Azevedo Marques (toim.), MEDINFO 2015: eHealth-enabled Health. IOS Press. Studies in Health Technology and InformaticsY 216. s. 1116. 2015 -
Brivaracetam in Unverricht-Lundborg disease (EPM1): Results from two randomized, double-blind, placebo-controlled studies
Kälviäinen Reetta, Genton Pierre, Andermann Eva, Andermann Frederick, Magaudda Adriana, Frucht Steven J, Schlit Anne-Françoise, Gerard Danielle, de la Loge Christine, von Rosenstiel Philipp. EPILEPSIA (NY) 57 2 (2016): 210-221. 2015 -
Intranasal therapies for acute seizures
Kälviäinen Reetta. EPILEPSY & BEHAVIOR 49: 303-306. 2015 -
Progressive Myoclonus Epilepsies
Kälviäinen Reetta. Seminars in Neurology 35 3: 293-299. 2015 -
Tiagabine
Kälviäinen Reetta. Teoksessa: Shorvon Simon D, Perucca Emilio, Engel Jerome Jr. (Eds.) (toim.) Treatment of Epilepsy (4th Edition). WILEY-BLACKWELL. s. 633-641. 2015 -
Reduced cortical activation in inferior frontal junction in Unverricht-Lundborg disease (EPM1) - A motor fMRI study
Könönen Mervi, Danner Nils, Koskenkorva Päivi, Kälviäinen Reetta, Hyppönen Jelena, Mervaala Esa, Karjalainen Pasi, Vanninen Ritva, Niskanen Eini. EPILEPSY RESEARCH 111: 78-84. 2015 -
Non-invasive mapping of bilateral motor speech areas using navigated transcranial magnetic stimulation and functional magnetic resonance imaging
Könönen Mervi, Tamsi Niko, Säisänen Laura, Kemppainen Samuli, Määttä Sara, Julkunen Petro, Jutila Leena, Äikiä Marja, Kälviäinen Reetta, Niskanen Eini, Vanninen Ritva, Karjalainen Pasi, Mervaala Esa. JOURNAL OF NEUROSCIENCE METHODS 248: 32-40. 2015 -
Forehead EEG electrode set versus full-head scalp EEG in 100 patients with altered mental state
Muraja-Murro Anu, Mervaala Esa, Westeren-Punnonen Susanna, Lepola Pasi, Töyräs Juha, Myllymaa Sami, Julkunen Petro, Kantanen Anne-Mari, Kälviäinen Reetta, Myllymaa Katja. EPILEPSY & BEHAVIOR 49: 245-249. 2015 -
Therapeutic misconception correlates with willingness to participate in clinical drug trials among patients with epilepsy: need for better counseling
Reijula Emmi, Halkoaho Arja, Pietilä Anna-Maija, Selander Tuomas, Kälviäinen Reetta, Keränen Tapani. 2015. Therapeutic misconception correlates with willingness to participate in clinical drug trials among patients with epilepsy; need for better counseling. EPILEPSY & BEHAVIOR 48: 29-34. 2015 -
Long-term adjunctive lacosamide treatment in patients with partial-onset seizures
Rosenow F, Kelemen A, Ben-Menachem E, McShea C, Isojarvi J, Doty P on behalf of the SP774 study investigators (incl. Reetta Kälviäinen). ACTA NEUROLOGICA SCANDINAVICA 133 2 (February 2016): 136-144. 2015 -
Temporal anteroinferior encephalocele: An underrecognized etiology of temporal lobe epilepsy?
Saavalainen Taavi, Jutila Leena, Mervaala Esa, Kälviäinen Reetta, Vanninen Ritva, Immonen Arto. NEUROLOGY [epub ahead of print Sep 25, 2015]: -. 2015 -
Dose-dependent teratogenicity of valproate in mono- and polytherapy : An observational study
Tomson Torbjörn, Battino Dina, Bonizzoni Erminio, Craig John, Lindhout Dick, Perucca Emilio, Sabers Anne, Thomas Sanjeev V, Vajda Frank for the EURAP Study Group (incl. Reetta Kälviäinen). NEUROLOGY online before print June 17, 2015. 2015 -
Valproate in the treatment of epilepsy in girls and women of childbearing potential
Tomson Torbjörn, Marson Anthony, Boon Paul, Canevini Maria Paola, Covanis Athanasios, Gaily Eija, Kälviäinen Reetta, Trinka Eugen. EPILEPSIA (NY) 56 7: 1006-10019. 2015 -
Genetic determinants of common epilepsies: a meta-analysis of genome-wide association studies
Anney RJ, Avbersek A, Balding D, Baum L, Becker F, Berkovic SF, Bradfield JP, Brody LC, Buono RJ, Catarino CB, Cavalleri GL, Cherny SS, Chinthapalli K, Coffey AJ, Compston A, Cossette P, de Haan G-H, De Jonghe P, de Kovel CGF, ..., Kälviäinen R, et al., International League Against Epilepsy Consortium on Complex Epilepsies ,. LANCET NEUROLOGY 13: 893-903. 2014 -
Acute Liver Failure After Valproate Exposure in Patients With POLG1 Mutations and the Prognosis After Liver Transplantation
Hynynen J, Komulainen T, Tukiainen E, Nordin A, Arola J, Kälviäinen R, Jutila L, Röyttä M, Hinttala R, Majamaa K, Mäkisalo H, Uusimaa J. LIVER TRANSPLANTATION 20 11: 1402-1412. 2014 -
Long-term memory performance after surgical treatment of unilateral temporal lobe epilepsy (TLE)
Jutila Leena, Äikiä Marja, Immonen Arto, Mervaala Esa, Alafuzoff Irina, Kälviäinen Reetta. EPILEPSY RESEARCH 108 7: 1228-1237. 2014 -
Transcranial magnetic stimulation for the diagnosis and treatment of epilepsy
Kimiskidis Vasilios K, Valentin Antionio, Kälviäinen Reetta. CURRENT OPINION IN NEUROLOGY (PHILADELPHIA PA) 27 2: 236-241. 2014 -
Alterations of motor cortical excitability and anatomy in Unverricht-Lundborg disease
Danner N, Julkunen P, Hyppönen J, Niskanen E, Säisänen L, Könönen M, Koskenkorva P, Vanninen R, Kälviäinen R, Mervaala E. MOVEMENT DISORDERS (NEW YORK NY) 28 13: 1860-1867. 2013 -
Updated ILAE evidence review of antiepileptic drug efficacy and effectiveness as initial monotherapy for epileptic seizures and syndromes
Glauser T, Ben-Menachem E, Bourgeois B, Cnaan A, Guerreiro C, Kälviäinen R, Mattson R, French JA, Perucca E, Tomson T. EPILEPSIA (NY) 54 3: 551-563. 2013 -
TMS-EEG reveals impaired intracortical interactions and coherence in Unverricht-Lundborg type progressive myoclonus epilepsy (EPM1)
Julkunen P, Säisänen L, Könönen M, Vanninen R, Kälviäinen R, Mervaala E. EPILEPSY RESEARCH S0920-1211 13: 00103-4. 2013 -
Epilepsy, hippocampal sclerosis and febrile seizures linked by common genetic variation around SCN1A
Kasperaviciute Dalia, Catarino Claudia B, Matarin Mar, Leu Costin, Novy Jan, Tostevin Anna, Leal Barbara, Hessel Ellen VS, Hallman Kerstin, Hildebrand Michael S, Dahl Hans-Henrik M, Ryten Mina, Trabzuni Daniah, Ramasamy Adaikalavan, Alhusaini Saud, Doherty Colin P, Dorn Thomas, Hansen Jörg, Krämer Gunter, Steinhoff Bernhard J, Zumsteg Dominik, Duncan Susan, Kälviäinen Reetta K et.al.. BRAIN Published online: 1-11. 2013 -
White Matter Degeneration with Unverricht-Lundborg Progressive Myoclonus Epilepsy: A Translational Diffusion-Tensor Imaging Study in Patients and Cystatin B-Deficient Mice
Manninen O, Koskenkorva P, Lehtimäki KK, Hyppönen J, Könönen M, Laitinen T, Kalimo H, Kopra O, Kälviäinen R, Gröhn O, Lehesjoki AE, Vanninen R. RADIOLOGY 2013 Jun 20. [Epub ahead of print]: --. 2013 -
Infertility treatment and umbilical cord length-novel markers of childhood epilepsy?
Räisänen S, Sokka A, Georgiadis L, Harju M, Gissler M, Keski-Nisula L, Kälviäinen R, Heinonen S. PLOS ONE [ONLINE] 8 2: e55394. 2013 -
3D Texture Analysis Reveals Imperceptible MRI Textural Alterations in the Thalamus and Putamen in Progressive Myoclonic Epilepsy Type 1, EPM1
Suoranta S, Holli-Helenius K, Koskenkorva P, Niskanen E, Könönen M, Aikiä M, Eskola H, Kälviäinen R, Vanninen R. PLOS ONE [ONLINE] 8 7: e69905. 2013 -
The Written Declaration on Epilepsy: An important achievement for Europe and beyond
Baulac M, De Boer H, Elger C, Glynn M, Kälviäinen R, Little A, Mifsud J, Perucca E, Pitkänen A. SEIZURE 21: 75-76. 2012 -
Sensorimotor, visual, and auditory cortical atrophy in Unverricht-Lundborg Disease mapped with cortical thickness analysis
Koskenkorva P, Niskanen E, Hyppönen J, Könönen M, Mervaala E, Soininen H, Kälviäinen R, Vanninen R. AJNR. AMERICAN JOURNAL OF NEURORADIOLOGY 33: 878-883. 2012 -
Structural brain imaging
Kälviäinen R, Dörfler A. Teoksessa: Stefan H, Theodore WH (toim.), Handbook of Clinical Neurology. ss. 359-368. 2012 -
The effect of fMRI task combinations on determining the hemispheric dominance of language functions
Niskanen E, Könönen M, Villberg V, Nissi M, Ranta-aho P, Säisänen L, Karjalainen P, Äikiä M, Kälviäinen R, Mervaala E, Vanninen R. NEURORADIOLOGY 54: 393-405. 2012 -
Thickened skull, scoliosis and other skeletal findings in Unverricht-Lundborg disease link cystatin B function to bone metabolism
Suoranta S, Manninen H, Koskenkorva P, Könönen M, Laitinen R, Lehesjoki AE, Kälviäinen R, Vanninen R. BONE 51 6: 1016-1024. 2012 -
KOMET: an unblinded, randomised, two parallel-group, stratified trial comparing the effectiveness of levetiracetam with controlled-release carbamazepine and extended-release sodium valproate as monotherapy in patients with newly diagnosed epilepsy
Trinka E, Marson AG, Van Paesschen W, Kälviäinen R, Marovac J, Duncan B, Buyle S, Hallström Y, Hon P, Muscas GC, Newton M, Meencke H-J, Smith PE, Pohlmann-Eden B. JOURNAL OF NEUROLOGY, NEUROSURGERY AND PSYCHIATRY - 2012 Aug 29. [Epub ahead of print]: 1-10. 2012 -
Primary motor cortex alterations in a compound heterozygous form of Unverricht-Lundborg disease (EPM1)
Danner N, Julkunen P, Könönen M, Hyppönen J, Koskenkorva P, Vanninen R, Lehesjoki A-E, Kälviäinen R, Mervaala E. SEIZURE 20: 65-71. 2011 -
Motor cortical plasticity is impaired in Unverricht-Lundborg Disease
Danner N, Säisänen L, Määttä S, Julkunen P, Hukkanen T, Könönen M, Hyppönen J, Kälviäinen R, Mervaala E. MOVEMENT DISORDERS (NEW YORK NY) 26: 2095-2100. 2011 -
Motor cortical plasticity is impaired in Unverrich-Lundborg disease
Danner Nils, Säisänen Laura, Määttä Sara, Julkunen Petro, Hukkanen Taina, Könönen Mervi, Hyppönen Jelena, Kälviäinen Reetta, Mervaala Esa. MOVEMENT DISORDERS (NEW YORK NY) 26 11: 2095-2100. 2011 -
Severer phenotype in Unverricht-Lundborg disease (EPM1) patients compound heterozygous for the dodecamer repeat expansion and the c.202C>T mutation in the CSTB gene
Koskenkorva P, Hyppönen J, Aikiä M, Mervaala E, Kiviranta T, Eriksson K, Lehesjoki AE, Vanninen R, Kälviäinen R.. NEURODEGENERATIVE DISEASES 8 6: 515-522. 2011 -
Late-onset Rasmussen's encephalitis and long-term remission
Kupila L, Jutila L, Immonen A, Vanninen R, Mervaala E, Pateau A, Luostarinen L, Kälviäinen R. EPILEPTIC DISORDERS 13 1: 88-91. 2011 -
Efficacy and safety of pregabalin versus lamotrigine in patients with newly diagnosed partial seizures: a phase 3, double-blind, randomised, parallel-group trial
Kwan P, Brodie MJ, Kälviäinen R, Yurkewicz L, Weaver J, Knapp LE. LANCET NEUROLOGY 10: 881-890. 2011 -
Non-vision adverse events with vigabatrin therapy
Walker SD, Kälviäinen R. ACTA NEUROLOGICA SCANDINAVICA 124: 72-82. 2011 -
Long-term neurocognitive adverse effects of prenatal antiepileptic drug exposure
Eriksson K & Kälviäinen R. Expert Review of Clinical Pharmacology 3 1: 131-137. 2010 -
Mitokondriaalinen resessiivinen ataksiasyndrooma ja valproaattihoidon toksisuus
Hakonen AH, Isohanni P, Rantamäki M, Kälviäinen R, Nordin A, Uusimaa J, Paetau A, Udd B, Pihko H & Wartiovaara A. DUODECIM 126: 1552-1559. 2010 -
Rare deletions at 16p13.11 predispose to a diverse spectrum of sporadic epilepsy syndromes
Heinzen EL, Radtke RA, Urban TJ, Cavalleri GL, Depondt C, Need AC, Walley NM, Nicoletti P, Ge D, Catarino CB et al. AMERICAN JOURNAL OF HUMAN GENETICS 86: 707-718. 2010 -
Long-term epilepsy surgery outcomes in patients with MRI-negative temporal lobe epilepsy
Immonen A, Jutila L, Muraja-MurroA, Mervaala E, Äikiä M, Lamusuo S, Kuikka J, Vanninen E, Alafuzoff I, Ikonen A, Vanninen R, Vapalahti M & Kälviäinen R. EPILEPSIA (NY) 51 11: 2260-2269. 2010 -
Common genetic variation and susceptibility to partial epilepsies: a genome-wide association study
Kasperaviciute D, Catarino CB, Heinzen EL, Depondt C, Cavalleri GL, Caboclo LO, Tate SK, Jamnadas-Khoda J et al. BRAIN 133: 2136-2147. 2010 -
Can BIS monitoring be used to assess the depth of propofol anesthesia in the treatment of refractory status epilepticus?
Musialowicz T, Mervaala E, Kälviäinen R, Uusaro A, Ruokonen E & Parviainen I. EPILEPSIA (NY) 51 8: 1580-1586. 2010 -
Pregabalin in partial seizures: a pragmatic 21-week, open-label study (PREPS)
Ryvlin P, Kälviäinen R, Von Raison F, Giordano S, Emir B & Chatamra K. EUROPEAN JOURNAL OF NEUROLOGY 17: 726-732. 2010 -
Is reduced ornithine-gamma-aminotransferase activity the cause of vigabatrin-associated visual field defects?
Sorri I, Brigell MG, Malyusz M, Mahlamäki E, de Meynard C & Kälviäinen R. EPILEPSY RESEARCH 92: 48-53. 2010 -
Carisbamate as adjunctive treatment of partial onset seizures in adults in two randomized, placebo-controlled trials
Sperling MR, Greenspan A, Cramer JA, Kwan P, Kälviäinen R, Halford JJ, Schmitt J, Yuen E et al. EPILEPSIA (NY) 51 3: 333-343. 2010 -
Non-invasive preoperative localization of primary motor cortex in epilepsy surgery by navigated transcranial magnetic stimulation
Säisänen L, Könönen M, Julkunen P, Määttä S, Vanninen R, Immonen A, Jutila L, Kälviäinen R, Jääskeläinen JE & Mervaala E. EPILEPSY RESEARCH 92: 134-144. 2010 -
Altered cortical inhibition in Unverricht-Lundborg type progressive myoclonus epilepsy (EPM1)
Danner N, Julkunen P, Khyuppenen J, Hukkanen T, Könönen M, Säisänen L, Koskenkorva P, Vanninen R, Lehesjoki AE, Kälviäinen R, Mervaala E, Könönen M. EPILEPSY RESEARCH 85: 81-88. 2009 -
Fosphenytoin
Eriksson K, Keränen T, Kälviäinen R. EXPERT OPINION ON DRUG METABOLISM AND TOXICOLOGY 5 6: 695-701. 2009 -
Adjunctive lacosamide for partial-onset seizures: Efficacy and safety from a randomized controlled trial
Halász P, Kälviäinen R, Mazurkiewicz-Beldrinska M, Rosenow F, Doty P, Hebert D, Sullivan T, on behalf of the SP755 STUDY Group. EPILEPSIA (NY) 50: 443-453. 2009 -
Motor cortex and thalamic atrophy in Unverricht-Lundborg disease: Voxel-based morphometric study
Koskenkorva P, Khyuppenen J, Niskanen E, Könönen M, Bendel P, Mervaala E, Lehesjoki AE, Kälviäinen R, Vanninen R, Könönen M. NEUROLOGY 73: 606-611. 2009 -
Clinical trials in status epilepticus-The clinical perspective
Kälviäinen R. EPILEPSIA. SUPPLEMENT 50: 75-76. 2009 -
An assessment of the Irish population for large-scale genetic mapping studies involving epilepsy an other complex diseases
O'Dushlaine CT, Dolan C, Weale ME, Stanton A, Croke DT, Kalviainen R, Eriksson K, Kantanen AM, Gibson RA, Hosford D, Sisodiya SM, Gill M, Corvin AP, Morris DW, Delanty N, Cavalleri GL. EUROPEAN JOURNAL OF HUMAN GENETICS 16: 176-183. 2008 -
Aikuisten epilepsiat
Suomalaisen Lääkäriseuran Duodecimin ja , Suomen Neurologinen Yhdistys ry:n asettama työryhmä, Kälviäinen R, Vapalahti M. DUODECIM 24: 2874-2888. 2008 -
Multicentre search for genetic susceptibility loci in sporadic epilepsy syndrome and seizure types: a case control-study
Cavalleri GL, Weale ME, Shianna KV, Singh R, Lynch JM, Grinton B, Szoeke C, Murphy K, Kinirons P, O'Rourke D, Ge D, Depondt C, Claeys KG, Pandolfo M, Gumbs C, Walley N, McNamara J, Mulley JC, Linney KN, Sheffield LJ, Radtke RA, Tate SK, Chissoe ST, Gibson RA, Hosford D, Stanton A, Graves TD, Hanna MG, Eriksson K, Kantanen A-M, Kalviainen R, ...... LANCET NEUROLOGY 6: 970-980. 2007 -
More severe epilepsy and cognitive impairment in the offspring of a mother with mosaicism for the ring 20 chromosome
Herrgård E, Mononen T, Mervaala E, Kuusela L, Äikiä M, Stenbäck U, Pääkkönen L, Airaksinen R-L, Kälviäinen R. EPILEPSY RESEARCH 73 1: 122-128. 2007 -
Social functioning and psychological well-being of 347 young adults with epilpsy only-population-based, controlled study from Finland
Koponen A, Seppälä U, Eriksson K, Nieminen P, Uutela A, Sillanpää M, Hyvärinen L, Kälviäinen R. EPILEPSIA (NY) 48 5: 907-912. 2007 -
Juvenile-onset neuronal ceroid lipofuscinosis with infantile CNL1 mutation and palmitoyl-protein thioesterase deficiency
Kälviäinen R, Eriksson K, Losekoot M, Sorri I, Harvima I, Santavuori P, Järvelä I, Autti T, Vanninen R, Salmenperä T, van Diggelen OP. EUROPEAN JOURNAL OF NEUROLOGY 14: 369-372. 2007 -
Status epilepticus treatment guidelines
Kälviäinen R. EPILEPSIA. SUPPLEMENT 48 8: 99-102. 2007 -
Increased expression of caspase 2 in experimental and human temporal lobe epilepsy
Narkilahti S, Jutila L, Alafuzoff I, Karkola K, Paljärvi L, Immonen A, Vapalahti M, Mervaala E, Kälviäinen R, Pitkänen A. NEUROMOLECULAR MEDICINE 9 2: 129-144. 2007 -
Propofol and barbiturates for the anesthesia of refractory convulsive status epilepticus: pros and cons
Parviainen I, Kälviäinen R, Ruokonen E. NEUROLOGICAL RESEARCH 29 7: 667-671. 2007 -
Fertility in women with active epilepsy
Viinikainen K, Heinonen S, Eriksson K, Kälviäinen R. NEUROLOGY 69: 2107-2108. 2007 -
ILAE treatment guidelines: evidence-based analysis of antiepileptic drug efficacy and effectiveness as initial monotherapy for epileptic seizures and syndromes
Glauser T, Ben-Menachem E, Bourgeois B, Cnaan A, Chadwick D, Guerreiro C, Kalviainen R, Mattson R, Perucca E, Tomson T. EPILEPSIA (NY) 47 7: 1094-1120. 2006 -
Optimizing treatment of epilepsy during pregnancy
Kälviäinen R, Tomson T. NEUROLOGY. SUPPLEMENT 67 4: S59-S63. 2006 -
Propofol in the treatment of refractory status epilepticus
Parviainen I, Uusaro A, Kälviäinen R, Mervaala E, Ruokonen E. INTENSIVE CARE MEDICINE 32: 1075-1079. 2006 -
Temporal changes in the incidence of epilepsy in Finland: nationwide study
Sillanpää M, Kälviäinen R, Klaukka T, Helenius H, Shinnar S. EPILEPSY RESEARCH 71: 206-215. 2006 -
The effects of valproate exposure in utero on behavior and the need for educational support in school-aged children
Viinikainen K, Eriksson K, Mönkkönen A, Äikiä M, Nieminen P, Heinonen S, Kälviäinen R. EPILEPSY & BEHAVIOR 9: 636-640. 2006 -
Community-based, prostective, controlled study of obstetric and neonatal outcome of 179 pregnancies in women with epilepsy
Viinikainen K, Heinonen S, Eriksson K, Kälviäinen R. EPILEPSIA (NY) 47 1: 186-192. 2006 -
Comparison of the cognitive effects of tiagabine and carbamazepine as monotherapy in newly diagnosed adult patients with partial epilepsy: pooled analysis of two long-term, randomized, follow-up studies
Äikiä M, Jutila L, Salmenperä T, Mervaala E, Kälviäinen R. EPILEPSIA (NY) 47 7: 1121-1127. 2006 -
Long-term effects of tiagabine monotherapy on cognition and mood in adult patients with chronic partial epilepsy
Äikiä M, Jutila L, Salmenperä T, Mervaala E, Kälviäinen R. EPILEPSY & BEHAVIOR 8 4: 750-755. 2006 -
Multi-detector row CT angiography in the assessment of carotid artery disease in the symtomatic patients: comparison with rotaional angiography and digital subtraction angiography
Berg M, Zhang Z, Ikonen A, Sipola P, Kälviäinen R, Manninen H, Vanninen R. AJNR. AMERICAN JOURNAL OF NEURORADIOLOGY 26: 1022-1034. 2005 -
Pharmacologic management of convulsive status epilepticus in childhood
Eriksson K, Kälviäinen R. EXPERT REVIEW OF NEUROTHERAPEUTICS 5 6: 777-783. 2005 -
Kohtausten hoidosta epilepsian hoitoon - tunnista epilepsiaoireyhtymä
Eriksson K, Peltola J, Kälviäinen R. DUODECIM 121: 505-512. 2005 -
Children exposed to valproate in utero-Population based evaluation of risks and confounding factors for long-term neurocognitive development
Eriksson K, Viinikainen K, Mönkkönen A, Äikiä M, Nieminen P, Heinonen S, Kälviäinen R. EPILEPSY RESEARCH 65: 189-200. 2005 -
MR volumetric analysis of the piriform cortex and cortical amygdala in drug-refractory temporal lobe epilepsy
Goncalves Pereira PM, Insausti R, Artacho-Pérula E, Salmenperä T, Kälviäinen R, Pitkänen A. AJNR. AMERICAN JOURNAL OF NEURORADIOLOGY 26: 319-332. 2005 -
Refractory generalised convulsive status epilepticus - A guide to treatment
Kälviäinen R, Eriksson K, Parviainen I. CNS DRUGS 19 9: 759-768. 2005 -
Status epilepticuksen hoito - ennusteeseen voidaan vaikuttaa tehokkaalla varhaisella hoidolla
Kälviäinen R. ERIKOISLÄÄKÄRI 15 6: 239-242. 2005 -
Cystatin C expression is associated with granule cell dispersion in epilepsy
Pirttilä TJ, Manninen A, Jutila L, Nissinen J, Kälviäinen R, Vapalahti M, Immonen A, Paljärvi L, Karkola K, Alafuzoff I, Mervaala E, Pitkänen A. ANNALS OF NEUROLOGY 58 2: 211-223. 2005 -
Hippocampal damage in newly diagnosed focal epilepsy: a prospective MRI study
Salmenperä T, Könönen M, Roberts N, Vanninen R, Pitkänen A, Kälviäinen R, Könönen M. NEUROLOGY 64: 62-68. 2005 -
Ophthalmologic and neurologic findings in two children exposed to vigabatrin in utero
Sorri I, Herrgård E, Viinikainen K, Pääkkönen A, Heinonen S, Kälviäinen R. EPILEPSY RESEARCH 65: 117-120. 2005 -
Color vision and contrast sensitivity in epilepsy patients treated with initial tiagabine monotherapy
Sorri I, Kälviäinen R, Mäntyjärvi M. EPILEPSY RESEARCH 67 3: 101-107. 2005 -
Visual function in epilepsy patients treated with initial valproate monotherapy
Sorri I, Rissanen E, Mäntyjärvi M, Kälviäinen R. SEIZURE 14: 367-370. 2005 -
Carotid stenosis degree in CT angiography: assessment based on luminal area versus luminal diameter measurements
Zhang Z, Berg M, Ikonen A, Könönen M, Kälviäinen R, Manninen H, Vanninen R, Könönen M. EUROPEAN RADIOLOGY 15: 2359-2365. 2005 -
Preoperative clinical evaluation, outline of surgical technique and outcome in termporal lobe epilepsy
Immonen A, Jutila L, Kälviäinen R, Mervaala E, Partanen K, Partanen J, Vanninen R, Ylinen A, Alafuzoff I, Paljärvi L, Hurskainen H, Rinne J, Puranen M, Vapalahti M. ADVANCES AND TECHNICAL STANDARDS IN NEUROSURGERY 29: 87-132. 2004 -
A woman with seven monotherapies
Kälviäinen R. EPILEPSY & BEHAVIOR. SUPPLEMENT 4: S8-S11. 2003 -
Long term outcome of temporal lobe epilepsy surgery: analyses of 140 consecutive patients
Jutila L, Immonen A, Mervaala E, Partanen J, Partanen K, Puranen M, Kälviäinen R, Alafuzoff I, Hurskainen H, Vapalahti M, Ylinen A. JOURNAL OF NEUROLOGY, NEUROSURGERY AND PSYCHIATRY 73: 486-494. 2002 -
Do recurrent seizures cause neuronal damage? A series of studies with MRI volumetry in adults with partial epilepsy
Kälviäinen R, Salmenperä T. Sutula T, Pitkänen A, Do Seizures Damage the Brain.Elsevier. Progress in Brain Research. 279-295. 2002 -
Temporal lobe resection in a patient with severe psychiatric problems
Kälviäinen R. Schmidt D, Schachter SC, 110 Puzzling Cases of Epilepsy.Martin Dunitz. 395-397. 2002 -
High-dose thiopental in the treatment of refractory status epilepticus in intensive care unit
Parviainen I, Uusaro A, Kälviäinen R, Kaukanen E, Mervaala E, Ruokonen E. NEUROLOGY 59: 1249-1251. 2002 -
Visual field defects with vigabatrin. Epidemiology and therapeutic implications
Kälviäinen R, Nousiainen I. CNS DRUGS 15 3: 217-230. 2001 -
Kognitiiviset häiriöt neurologisissa sairauksissa. Epilepsia
Kälviäinen R, Äikiä M. Erkinjuntti T, Rinne J, Alhainen K, Soininen H, Muistihäiriöt ja dementia.Duodecim. 274-278. 2001 -
Long-term safety of tiagabine
Kälviäinen R. EPILEPSIA. SUPPLEMENT 42 3: 46-48. 2001 -
Monotherapy trial design: conversion versus de novo
Kälviäinen R. EPILEPSY RESEARCH 45: 75-78. 2001 -
[18F] FDG-PET reveals temporal hypometabolism in patients with temporal lobe epilepsy even when quantitative MRI and histopathological analysis show only mild hippocampal damage
Lamusuo S, Jutila L, Ylinen A, Kälviäinen R, Mervaala E, Haaparanta M, Jääskeläinen S, Partanen K, Vapalahti M, Rinne J. ARCHIVES OF NEUROLOGY 58: 933-939. 2001 -
No reversion in vigabatrin-associated visual field defects
Nousiainen I, Mäntyjärvi M, Kälviäinen R. NEUROLOGY 57: 1916-1917. 2001 -
Epilepsia ja ajokyvyn arviointi - suomalainen menettelyohje
Ojala M, Hyvärinen L, Juntunen J, Keränen T, Kälviäinen R, Mûller K, Wallin A. SUOMEN LÄÄKÄRILEHTI 56 49-50: 5121-5123. 2001 -
Insurability of patients with epilepsy: perspectives of physicians and insurance companies
Ojala M, Kälviäinen R. Teoksessa: Johannessen SI, Tomson T, Sillanpää M, Pedersen B (toim.), Medical Risks in Epilepsy.Wrightson Biomedical Publishing. ss. 139-140. 2001 -
Hippocampal and amygdaloid damage in partial epilepsy A cross-sectional MRI study of 241 patients
Salmenperä T, Kälviäinen R, Partanen K, Pitkänen A. EPILEPSY RESEARCH 46: 69-82. 2001 -
Recommendations on the clinical use of oxcarbazepine in the treatment of epilepsy: a consensus view
Schmidt D, Arroyo S, Baulac M, Dam M, Dulac O, Friis ML, Kälviäinen R, Krämer G, van Parys J, Pedersen B, Sachdeo R. ACTA NEUROLOGICA SCANDINAVICA 104: 167-170. 2001 -
Verbal memory in newly diagnosed patients and patients with chronic left temporal lobe epilepsy
Äikiä M, Salmenperä T, Partanen K, Kälviäinen R. EPILEPSY & BEHAVIOR 2: 20-27. 2001 -
Color vision in epilepsy patients treated with vigabatrin or carbamazepine monotherapy
Nousiainen I, Kälviäinen R, Mäntyjärvi M. OPHTHALMOLOGY 107: 884-888. 2000 -
Contrast and glare sensitivity in epilepsy patients treated with vigabatrin or carbamazepine monotherapy compared with healthy volunteers
Nousiainen I, Kälviäinen R, Mäntyjärvi M. BRITISH JOURNAL OF OPHTHALMOLOGY 84: 622-625. 2000 -
Visual function in patients with the GABAergic anticonvulsant drug tiagabine
Nousiainen I, Mäntyjärvi M, Kälviäinen R. CLINICAL DRUG INVESTIGATION 20 6: 393-400. 2000 -
MRI volumetry of the hippocampus, amygdala, entorhinal cortex, and perirhinal cortex after status epilepticus
Salmenperä T, Kälviäinen R, Partanen K, Mervaala E, Pitkänen A. EPILEPSY RESEARCH 40: 155-170. 2000 -
Quantitative MRI volumetry of the entorhinal cortex in temporal lobe epilepsy
Salmenperä T, Kälviäinen R, Partanen K, Pitkänen A. SEIZURE 9: 208-215. 2000 -
Tiagabine in the treatment of epilepsy - a clinical review with a guide for the prescibing physician
Schmidt D, Gram L, Brodie M, Krämer G, Perucca E, Kälviäinen R, Elger CE. EPILEPSY RESEARCH 41: 245-251. 2000 -
Safety and efficscy of vigabatrin and carbamazepine in newly diagnosed epilepsy: a multicentre randomised double-blind study
Chadwick D, for the Vigabatrin European Monotherapy Study Group, Kälviäinen R. LANCET 354: 13-19. 1999 -
Vigabatrin, a gabaergic antiepileptic drug, causes concentric visual field defects
Kälviäinen R, Nousiainen I, Mäntyjärvi M, Nikoskelainen E, Partanen J, Partanen K, Riekkinen P Sr. NEUROLOGY 53: 922-926. 1999 -
Prevention of seizure-induced neuronal damage and intellectual deterioration: experimental aspects and clinical implications
Kälviäinen R, Pitkänen A. Teoksessa: Sillanpää M, Gram L, Johannessen SI, Tomson T (toim.), Epilepsy and Mental Retardation.Wrightson Biomedical Publishing . ss. 165 - 178. 1999 -
Cognitive effects of GABAergic antiepileptic drugs
Kälviäinen R. ELECTROENCEPHALOGRAPHY AND CLINICAL NEUROPHYSIOLOGY. SUPPLEMENT 50: 458-464. 1999 -
Seizure-induced damage to the medial temporal lobe in temporal lobe epilepsy
Pitkänen A, Salmenperä T, Äikiä M, Partanen K, Kälviäinen R. Sillanpää M, Gram L, Johannessen SI, Tomson T, Epilepsy and Mental Retardation.Wrightson Biomedical Publishing . 147-163. 1999 -
Predictors of seizure outcome in newly diagnosed partial epilepsy: memory performance as a prognostic factor
Äikiä M, Kälviäinen R, Mervaala E, Riekkinen PJ Sr. EPILEPSY RESEARCH 37: 159-167. 1999 -
Recurrent seizures may cause hippocampal damage in temporal lobe epilepsy
Kälviäinen R, Salmenperä T, Partanen K, Vainio P, Riekkinen P Sr, Pitkänen A. NEUROLOGY 50: 1377-1382. 1998 -
Remodeling of neuronal circuitries in human temporal lobe epilepsy: increased expression of highly polysialylated neural cell adhesion molecule in the hippocampus and the entorhinal cortex
Mikkonen M, Soininen H, Kälviäinen R, Tapiola T, Ylinen A, Vapalahti M, Paljärvi L, Pitkänen A. ANNALS OF NEUROLOGY 44: 923-934. 1998 -
Amygdala damage in experimental and human temporal lobe epilepsy
Pitkänen A, Tuunanen J, Kälviäinen R, Partanen K, Salmenperä T. EPILEPSY RESEARCH 32: 233-253. 1998 -
Hippocampal damage caused by seizures in temporal lobe epilepsy
Salmenperä T, Kälviäinen R, Partanen K, Pitkänen A. LANCET 351: 35. 1998 -
MRI-based hippocampal volumetry and T2 relaxometry: correlation to verbal memory performance in newly diagnosed epilepsy patients with left-sided temporal lobe focus
Kälviäinen R, Partanen K, Äikiä M, Mervaala E, Vainio P, Riekkinen PJ Sr, Pitkänen A. NEUROLOGY 48: 286-287. 1997 -
MRI volumetry and T2 relaxometry of the amygdala in newly diagnosed and chronic temporal lobe epilepsy
Kälviäinen R, Salmenperä T, Partanen K, Vainio P, Riekkinen P Sr, Pitkänen A. EPILEPSY RESEARCH 28: 39-50. 1997 -
Unstable insertion in the 5`flanking region of the cystatin B gene is the most common mutation in progressive myoclonus epilepsy type 1, EPM1
Lafreniére RG, Rochefort DL, Chrétien N, Rommens JM, Cochius JI, Kälviäinen R, Nousiainen U, Patry G, Farrell K, Söderfeldt B, Federico A, Hale BR, Cossio OH, Sorensen T, Pouliot MA, Kmiec T, Uldall P, Janszky J, Pranzatelli MR, Anderman F, Anderman. NATURE GENETICS 15: 298-302. 1997 -
Comparison of (18F) FDG-PET, (99mTc)-HMPAO-SPECT, and (123)-iomazenil-SPECT in localising the epileptogenic cortex
Lamusuo S, Ruottinen HM, Knuuti J, Härkönen R, Ruotsalainen U, Bergman J, Haaparanta M, Solin O, Mervaala E, Nousiainen U, Jääskeläinen S, Ylinen A, Kälviäinen R, Rinne JK, Vapalahti M, Rinne JO. JOURNAL OF NEUROLOGY, NEUROSURGERY AND PSYCHIATRY 63: 743-748. 1997 -
In reply (to Vigabatrin and carbamazepine monotherapy for newly diagnosed epilepsy)
Kälviäinen R, Riekkinen PJ Sr. ARCHIVES OF NEUROLOGY 53: 478. 1996 -
Long-term cognitive and EEG effects of tiagabine in drug-resistant partial epilepsy
Kälviäinen R, Äikiä M, Mervaala E, Saukkonen AM, Pitkänen A, Riekkinen PJ Sr. EPILEPSY RESEARCH 25: 291-297. 1996 -
Cognitive adverse effects of antiepileptic drugs. Incidence, mechanisms and therapeutic implications
Kälviäinen R, Äikiä M, Riekkinen PJ Sr. CNS DRUGS 5 5: 358-368. 1996 -
Severity of hippocampal atrophy correlates with the prolongation of MRI T2 relaxation time in temporal lobe epilepsy but not in Alzheimer's disease
Pitkänen A, Laakso M, Kälviäinen R, Partanen K, Vainio P, Lehtovirta M, Riekkinen P Sr, Soininen H. NEUROLOGY 46: 1724-1730. 1996 -
Cost of epilepsy: review of the literature
Salmenperä T, Kälviäinen R, Ylinen A, Riekkinen PJ Sr. NEUROLOGIST 2: 230-238. 1996 -
Vigabatrin. Clinical use
Kälviäinen R, Mervaala E, Sivenius J, Riekkinen PJ Sr. Levy RH, Mattson RH, Meldrum BS, Antiepileptic Drugs, Fourth Edition.Raven Press. 925-930. 1995 -
New anti-epileptic drugs
Kälviäinen R, Riekkinen PJ Sr. EXPERT OPINION ON INVESTIGATION DRUGS 4 10: 955-962. 1995 -
Vigabatrin vs carbamazepine monotherapy in patients with newly diagnosed epilepsy
Kälviäinen R, Äikiä M, Saukkonen AM, Mervaala E, Riekkinen PJ Sr. ARCHIVES OF NEUROLOGY 52: 989-996. 1995 -
Long-term efficacy and cognitive effects of vigabatrin
Ylinen A, Kälviäinen R, Riekkinen PJ Sr. ACTA NEUROLOGICA SCANDINAVICA. SUPPLEMENTUM 162: 47-50. 1995 -
Verbal learning and memory in newly diagnosed partial epilepsy
Äikiä M, Kälviäinen R, Riekkinen PJ. EPILEPSY RESEARCH 22: 157-164. 1995 -
Sweat gland vacuoles in Unverricht-Lundborg disease: A clue to diagnosis?
Cochius J, Carpenter S, Andermann E, Rouleau G, Nousiainen U, Kälviäinen R, Farrell K, Andermann F. NEUROLOGY 44: 2372-2375. 1994 -
Do seizures cause neuronal damage? A MRI study in newly diagnosed and chronic epilepsy
Saukkonen AM, Kälviäinen R, Partanen K, Vainio P, Riekkinen P, Pitkänen A. NEUROREPORT 6: 219-223. 1994