Riikka Lampinen
Tutkijatohtori
riikka.lampinen@uef.fi
Tutkimustyössäni olen kiinnostunut tutkimaan mitokondrioiden toimintahäiriöitä Alzheimerin taudissa. Käytämme tutkimuksessa potilasperäisiä solumalleja.
Tutkimusryhmät
Julkaisut
16/16 kappaletta-
A technological comparison of freeze-dried poly-ɛ-caprolactone (PCL) and poly (lactic-co-glycolic acid) (PLGA) nanoparticles loaded with clozapine for nose-to-brain delivery
Lombardo, Rosamaria; Ruponen, Marika; Rautio, Jarkko; Lampinen, Riikka; Kanninen, Katja M.; Koivisto, Anne M.; Penttilä, Elina; Löppönen, Heikki; Demartis, Sara; Giunchedi, Paolo; Rassu, Giovanna; Fragalà, Maria Elena; Pignatello, Rosario. 2024. Journal of drug delivery science and technology. 93: . 105419 -
Exposure to urban particulate matter alters responses of olfactory mucosal cells to SARS-CoV-2 infection
Shahbaz, Muhammad Ali; Kuivanen, Suvi; Mussalo, Laura; Afonin, Alexey M; Kumari, Kajal; Behzadpour, Donya; Kalapudas, Juho; Koivisto, Anne M; Penttilä, Elina; Löppönen, Heikki; Jalava, Pasi; Vapalahti, Olli; Balistreri, Giuseppe; Lampinen, Riikka; Kanninen, Katja M. 2024. Environmental research. 249: -
Traffic-related ultrafine particles impair mitochondrial functions in human olfactory mucosa cells – Implications for Alzheimer's disease
Mussalo, Laura; Lampinen, Riikka; Avesani, Simone; Závodná, Táňa; Krejčík, Zdeněk; Kalapudas, Juho; Penttilä, Elina; Löppönen, Heikki; Koivisto, Anne M; Malm, Tarja; Topinka, Jan; Giugno, Rosalba; Jalava, Pasi; Kanninen, Katja M. 2024. Redox biology. 75: -
Upregulation of Integrin beta-3 in astrocytes upon Alzheimer's disease progression in the 5xFAD mouse model
Ivanova, Mariia; Belaya, Irina; Kucháriková, Nina; de Sousa Maciel, Izaque; Saveleva, Liudmila; Alatalo, Arto; Juvonen, Ilona; Thind, Navjot; Andrès, Clarisse; Lampinen, Riikka; Chew, Sweelin; Kanninen, Katja M. 2024. Neurobiology of disease. 191: -
Development of Lyophilised Eudragit® Retard Nanoparticles for the Sustained Release of Clozapine via Intranasal Administration
Lombardo, Rosamaria; Ruponen, Marika; Rautio, Jarkko; Ghelardini, Carla; Di Cesare Mannelli, Lorenzo; Calosi, Laura; Bani, Daniele; Lampinen, Riikka; Kanninen, Katja M.; Koivisto, Anne M; Penttilä, Elina; Löppönen, Heikki; Pignatello, Rosario. 2023. Pharmaceutics. 15: -
Emissions from modern engines induce distinct effects in human olfactory mucosa cells, depending on fuel and aftertreatment
Mussalo, Laura; Avesani, Simone; Shahbaz, Muhammad Ali; Zavodna, Tana; Saveleva, Liudmila; Järvinen, Anssi; Lampinen, Riikka; Belaya, Irina; Krejcik, Zdenek; Ivanova, Mariia; Hakkarainen, Henri; Kalapudas, Juho; Penttilä, Elina; Löppönen, Heikki; Koivisto, Anne M; Malm, Tarja; Topinka, Jan; Giugno, Rosalba; Aakko-Saksa, Päivi; Chew, Sweelin; Rönkkö, Topi; Jalava, Pasi; Kanninen, Katja M. 2023. Science of the total environment. 905: -
Human-derived air–liquid interface cultures decipher Alzheimer’s disease–SARS-CoV-2 crosstalk in the olfactory mucosa
Shahbaz, Muhammad Ali; Kuivanen, Suvi; Lampinen, Riikka; Mussalo, Laura; Hron, Tomáš; Závodná, Táňa; Ojha, Ravi; Krejčík, Zdeněk; Saveleva, Liudmila; Tahir, Numan Ahmad; Kalapudas, Juho; Koivisto, Anne M; Penttilä, Elina; Löppönen, Heikki; Singh, Prateek; Topinka, Jan; Vapalahti, Olli; Chew, Sweelin; Balistreri, Giuseppe; Kanninen, Katja M. 2023. Journal of neuroinflammation. 20: . 299 -
An Alzheimer’s Disease Patient-Derived Olfactory Stem Cell Model Identifies Gene Expression Changes Associated with Cognition
Rantanen, Laura M.; Bitar, Maina; Lampinen, Riikka; Stewart, Romal; Quek, Hazel; Oikari, Lotta E.; Cunί-Lόpez, Carla; Sutharsan, Ratneswary; Thillaiyampalam, Gayathri; Iqbal, Jamila; Russell, Daniel; Penttilä, Elina; Löppönen, Heikki; Lehtola, Juha-Matti; Saari, Toni; Hannonen, Sanna; Koivisto, Anne M.; Haupt, Larisa M.; Mackay-Sim, Alan; Cristino, Alexandre S.; Kanninen, Katja M.; White, Anthony R.. 2022. Cells. 11: -
Biometal Dyshomeostasis in Olfactory Mucosa of Alzheimer’s Disease Patients
Lampinen, Riikka; Górová, Veronika; Avesani, Simone; Liddell, Jeffrey R; Penttilä, Elina; Závodná, Táňa; Krejčík, Zdeněk; Lehtola, Juha-Matti; Saari, Toni; Kalapudas, Juho; Hannonen, Sanna; Löppönen, Heikki; Topinka, Jan; Koivisto, Anne M; White, Anthony R; Giugno, Rosalba; Kanninen, Katja M. 2022. International journal of molecular sciences. 23: -
Mitochondrial dysfunction in non-neuronal cells in Alzheimer’s disease
Lampinen, Riikka. 2022. Publications of the University of Eastern Finland. Dissertations in Health Sciences