Timo Lakka

Halali, F.; Lapveteläinen, A.; Aittola, K.; Männikkö, R.; Tilles-Tirkkonen, T.; Järvelä-Reijonen, E.; Absetz, P.; Kolehmainen, M.; Schwab, U.; Lindström, J.; Lakka, T. A.; Pihlajamäki, J.; Karhunen, L.. 2022. Associations between weight loss history and factors related to type 2 diabetes risk in the Stop Diabetes study International journal of obesity Published online: 12 January 2022: 1 - 8. 2022

Korhonen, Marika; Väisto, Juuso; Veijalainen, Aapo; Leppänen, Marja; Ekelund, Ulf; Laukkanen, Jari A; Brage, Soren; Lintu, Niina; Haapala, Eero A; Lakka, Timo A. 2021. Longitudinal associations of physical activity, sedentary time, and cardiorespiratory fitness with arterial health in children - the PANIC study Journal of sports sciences 39 17: 1980-1987. 2021

Aittola, Kirsikka; Karhunen, Leila; Männikkö, Reija; Järvelä-Reijonen, Elina; Mikkonen, Santtu; Absetz, Pilvikki; Kolehmainen, Marjukka; Schwab, Ursula; Harjumaa, Marja; Lindström, Jaana; Lakka, Timo; Tilles-Tirkkonen, Tanja; Pihlajamäki, Jussi. 2021. Enhanced Eating Competence Is Associated with Improved Diet Quality and Cardiometabolic Profile in Finnish Adults with Increased Risk of Type 2 Diabetes Nutrients 13 11: 4030. 2021

Väistö, Juuso; Haapala, Eero; Lakka, Timo A. 2021. Liikunnallisuus ja hyvä kunto ehkäisevät tyypin 2 diabetesta ja valtimotautien riskitekijöitä lapsuudesta lähtien Liikunta ja tiede 58 3: 62-64. 2021

Sun, Daokun; Richard, Melissa A.; Musani, Solomon K.; Sung, Yun Ju; Winkler, Thomas W.; Schwander, Karen; Chai, Jin Fang; Guo, Xiuqing; Kilpeläinen, Tuomas O.; Vojinovic, Dina; Aschard, Hugues; Bartz, Traci M.; Bielak, Lawrence F.; Brown, Michael R.; Chitrala, Kumaraswamy; Hartwig, Fernando P.; Horimoto, Andrea R.V.R.; Liu, Yongmei; Manning, Alisa K.; Noordam, Raymond et al. [incl. Heikkinen, Sam. 2021. Multi-ancestry genome-wide association study accounting for gene-psychosocial factor interactions identifies novel loci for blood pressure traits Human Genetics and Genomics Advances 2 1: 100013. 2021

Mägi, Reedik; Hottenga, Jouke- Jan; Grallert, Harald; Perry, John R. B.; Bouatia-Naji, Nabila; Marullo, Letizia; Rybin, Denis; Jansen, Rick; Min, Josine L.; Dimas, Antigone S.; Ulrich, Anna; Zudina, Liudmila; Gådin, Jesper R.; Jiang, Longda; Faggian, Alessia; Bonnefond, Amélie; Fadista, Joao; Stathopoulou, Maria G.; Isaacs, Aaron; Willems, Sara M et al. [incl. Kuusisto, Johanna; Laakso, Markku; La. 2021. Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability Nature communications 12 1: 24. 2021

Methuen, Mirja; Kauppinen, Sofia; Suominen, Anna Liisa; Eloranta, Aino-Maija; Väistö, Juuso; Lakka, Timo; Vähänikkilä, Hannu; Anttonen, Vuokko. 2021. Dental caries among Finnish teenagers participating in physical activity and diet intervention: association with anthropometrics and behavioural factors Bmc oral health 21 1: 333. 2021

Leppänen, Marja H; Haapala, Eero A; Väistö, Juuso; Ekelund, Ulf; Brage, Søren; Kilpeläinen, Tuomas O; Lakka, Timo A. 2021. Longitudinal and cross-sectional associations of adherence to 24-hour movement guidelines with cardiometabolic risk Scandinavian journal of medicine and science in sports 2022; 32 1: 255-266. 2021

Kårlund, Anna; Kääriäinen, Teemu; Kostamo, Vili M; Kokkola, Tarja; Kolehmainen, Marjukka; Lakka, Timo A; Pihlajamäki, Jussi; Manninen, Albert. 2021. Oxygen-18 and Carbon-13 isotopes in eCO 2 and erythrocytes carbonic anhydrase activity of Finnish prediabetic population Journal of breath research 15 2: 021001. 2021

Kuvaja-Köllner, Virpi; Lintu, Niina; Lindi, Virpi; Rissanen, Elisa; Eloranta, Aino-Maija; Kiiskinen, Sanna; Martikainen, Janne; Kankaanpää, Eila; Valtonen, Hannu; Lakka, Timo A.. 2021. Cost-effectiveness of physical activity intervention in children - results based on the Physical Activity and Nutrition in Children (PANIC) study International journal of behavioral nutrition and physical activity 18 1: 116. 2021

Komulainen, Pirjo; Tuomilehto, Jaakko; Savonen, Kai; Männikkö, Reija; Hassinen, Maija; Lakka, Timo A; Hänninen, Tuomo; Kiviniemi, Vesa; Jacobs, David R; Kivipelto, Miia; Rauramaa, Rainer. 2021. Exercise, diet, and cognition in a 4-year randomized controlled trial: Dose-Responses to Exercise Training (DR's EXTRA) American journal of clinical nutrition 113 6: 1428-1439. 2021

Joro, R; Korkmaz, A; Lakka, TA; Uusitalo, ALT; Atalay, M. 2021. Plasma irisin and its associations with oxidative stress in athletes suffering from overtraining syndrome Physiology international 10 4: 513-526. 2021

Jalkanen, Kari; Järvenpää, Riia; Tilles-Tirkkonen, Tanja; Martikainen, Janne; Aarnio, Emma; Männikkö, Reija; Rantala, Eeva; Karhunen, Leila; Kolehmainen, Marjukka; Harjumaa, Marja; Poutanen, Kaisa; Ermes, Miikka; Absetz, Pilvikki; Schwab, Ursula; Lakka, Timo; Pihlajamäki, Jussi; Lindström, Jaana; The StopDia Study Group. 2021. Comparison of Communication Channels for Large-Scale Type 2 Diabetes Risk Screening and Intervention Recruitment: Empirical Study JMIR diabetes 6 3: e21356. 2021

Hyvällä mielellä Pohjois-Savo -hankkeen esiselvitys: Toimenpide-ehdotus ja vaikuttavuuden arviointisuunnitelma. Saijonkari, Maija; Paronen, Elsa; Lakka, Timo; Tolmunen, Tommi; Linnosmaa, Ismo; Lammintakanen, Johanna; Mäki-Opas, Tomi. 2021 2021

Haapala, Eero A; Väistö, Juuso; Ihalainen, Johanna K; Tomaselli González, Claudia; Leppänen, Marja H; Veijalainen, Aapo; Sallinen, Taisa; Eloranta, Aino-Maija; Ekelund, Ulf; Schwab, Ursula; Brage, Soren; Atalay, Mustafa; Lakka, Timo A. 2021. Associations of physical activity, sedentary time, and diet quality with biomarkers of inflammation in children European journal of sport science [Epub ahead of print 14 March 2021]: 1-10. 2021

Haapala, Eero A; Barker, Alan R; Lakka, Timo A. 2021. Response Medicine and science in sports and exercise 53 2: 454. 2021

Constable, Annie M.; Porter, Josie E.; Benger, Danielle; Vlachopoulos, Dimitris; Barker, Alan R.; Moore, Sarah A.; Soininen, Sonja; Haapala, Eero A.; Westgate, Kate; Brage, Soren; Agostinete, Ricardo R.; Fernandes, Romulo A.; Lakka, Timo A.. 2021. The Positive Relationship between Moderate-to-Vigorous Physical Activity and Bone Mineral Content Is Not Mediated by Free Leptin Index in Prepubertal Children: The PANIC Study International journal of environmental research and public health 18 10: 5365. 2021

Constable, AM; Vlachopoulos, D; Barker, AR; Moore, SA; Soininen, S; Haapala, EA; Väistö, J; Westgate, K; Brage, S; Mähönen, A; Lakka, TA. 2021. The independent and interactive associations of physical activity intensity and vitamin D status with bone mineral density in prepubertal children: the PANIC Study Osteoporosis international 32 8: 1609-1620. 2021

Chen, J; Spracklen, CN; Marenne, G; Varshney, A; Corbin, LJ; Luan, J; Willems, SM; Wu, Y; Zhang, X; Horikoshi, M; Boutin, TS; Mägi, R; Waage, J; Li-Gao, R; Chan, KHK; Yao, J; Anasanti, MD; Chu, AY; Claringbould, A; Heikkinen, J; et al. [incl. Kuulasmaa, T; Kuusisto, J; Laakso, M; Lakka, T; Uusitupa, M; Vangipurapu, J]. 2021. The trans-ancestral genomic architecture of glycemic traits Nature genetics 53 6: 840-860. 2021

Savinainen, SE; Viitasalo, A; Sallinen, TM; Jääskeläinen, JES; Lakka, TA. 2020. Child-related and Parental Predictors for Thelarche in a General Population of Girls: The PANIC Study Pediatric research 88 4: 676-680. 2020

Vogelezang, Suzanne; Bradfield, Jonathan P; Ahluwalia, Tarunveer S; Curtin, John A; Lakka, Timo A; Grarup, Niels; Scholz, Markus; van der Most, Peter J; Monnereau, Claire; Stergiakouli, Evie; Heiskala, Anni; Horikoshi, Momoko; Fedko, Iryna O; Vilor-Tejedor, Natalia; Cousminer, Diana L; Standl, Marie; Wang, Carol A; Viikari, Jorma; Geller, Frank; Íñiguez, Carmen; et al. (Incl. Atalay, Mustafa; Lind. 2020. Novel loci for childhood body mass index and shared heritability with adult cardiometabolic traits PLoS genetics 16 10: e1008718. 2020

Tilles-Tirkkonen, Tanja; Männikkö, Reija; Lindström, Jaana; Harjumaa, Marja; Aittola, Kirsikka; Järvelä-Reijonen, Elina; Rantala, Eeva; Martikainen, Janne; Lakka, Timo; Pihlajamäki, Jussi. 2020. StopDia-hankkeesta vinkkejä terveyden edistämiseen ja hyte-johtamiseen Ravitsemusasiantuntija 6 1: 4-7. 2020

Säisänen, Laura; Könönen, Mervi; Niskanen, Eini; Lakka, Timo; Lintu, Niina; Vanninen, Ritva; Julkunen, Petro; Määttä, Sara. 2020. Primary hand motor representation areas in healthy children, preadolescents, adolescents, and adults Neuroimage 2021; 228: 117702. 2020

Surendran, Praveen; Feofanova, Elena V; Lahrouchi, Najim; Ntalla, Ioanna; Karthikeyan, Savita; Cook, James; Chen, Lingyan; Mifsud, Borbala; Yao, Chen; Kraja, Aldi T; Cartwright, James H; Hellwege, Jacklyn N; Giri, Ayush; Tragante, Vinicius; Thorleifsson, Gudmar; Liu, Dajiang J; Prins, Bram P; Stewart, Isobel D; Cabrera, Claudia P; Eales, James M; et al. (incl. Stanakova, Alena; Laatikainen, Tiina;. 2020. Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals Nature genetics 52: 1314-1332. 2020

Suomalaisten lasten ja nuorten ruokaympäristö ja toimenpide-ehdotukset sen kehittämiseen terveyttä edistäväksi. Rantala, Eeva; Martikainen, Janne; Lakka, Timo; Vanhatalo, Saara; Heiskanen, Jari; Väistö, Juuso; Leväsluoto, Johanna; Hassinen, Maija; Eloranta, Aino-Maija; Sigfrids, Anton; Harjumaa, Marja. 2020 2020

Haapala, Eero A; Gao, Ying; Lintu, Niina; Väistö, Juuso; Vanhala, Anssi; Tompuri, Tuomo; Lakka, Timo A; Finni, Taija. 2020. Associations between cardiorespiratory fitness, motor competence, and adiposity in children Translational sports medicine 2021; 4 1: 56-64. 2020

Naveed, Sehrish; Venäläinen, Taisa; Eloranta, Aino-Maija; Erkkilä, Arja; Jalkanen, Henna; Lindi, Virpi; Lakka, Timo; Haapala, Eero. 2020. Associations of dietary carbohydrate and fatty acid intakes with cognition among children Public health nutrition 23 9: 1657-1663. 2020

Lakka, Timo A; Lintu, Niina; Väistö, Juuso; Viitasalo, Anna; Sallinen, Taisa; Haapala, Eero A; Tompuri, Tuomo T; Soininen, Sonja; Karjalainen, Panu; Schnurr, Theresia M; Mikkonen, Santtu; Atalay, Mustafa; Kilpeläinen, Tuomas O; Laitinen, Tomi; Laaksonen, David E; Savonen, Kai; Brage, Soren; Schwab, Ursula; Jääskeläinen, Jarmo; Lindi, Virpi; Eloranta, Aino-Maija. 2020. A 2 year physical activity and dietary intervention attenuates the increase in insulin resistance in a general population of children: the PANIC study Diabetologia 63: 2270-2281. 2020

Kunutsor, Setor; Lakka, Timo; Kurl, Sudhir; Mäkikallio, Timo; Jae, Sae Young; Laukkanen, Jari. 2020. Leisure-time cross-country skiing and the risk of venous thromboembolism: A prospective cohort study European journal of preventive cardiology 2021; 28 10: 1138-1141. 2020

Eloranta, Aino-Maija; Sallinen, Taisa; Viitasalo, Anna; Lintu, Niina; Väistö, Juuso; Jalkanen, Henna; Tompuri, Tuomo T; Soininen, Sonja; Haapala, Eero A; Kiiskinen, Sanna; Schnurr, Theresia M; Kilpeläinen, Tuomas O; Mikkonen, Santtu; Savonen, Kai; Atalay, Mustafa; Brage, Soren; Laaksonen, David E; Lindi, Virpi; Ågren, Jyrki; Schwab, Ursula; et al. [incl. Jääskeläinen, Jarmo; Lakka, Timo]. 2020. The effects of a 2-year physical activity and dietary intervention on plasma lipid concentrations in children: the PANIC Study European journal of nutrition 2021; 60: 425-434. 2020

Effects of a 2-Year Lifestyle Intervention on Cardiorespiratory Fitness in 6-8- Year-Old Children: The PANIC Study. Agbaje, AO; Barker, AR; Eloranta, A-M; Haapala, EA; Lintu, N; Savonen, K; Kilpeläinen, TO; Brage, S; Lakka, TA. Pediatric exercise science. 2020. 2020

de Las Fuentes, Lisa; Sung, Yun Ju; Noordam, Raymond; Winkler, Thomas; Feitosa, Mary F; Schwander, Karen; Bentley, Amy R; Brown, Michael R; Guo, Xiuqing; Manning, Alisa; Chasman, Daniel I; Aschard, Hugues; Bartz, Traci M; Bielak, Lawrence F; Campbell, Archie; Cheng, Ching-Yu; Dorajoo, Rajkumar; Hartwig, Fernando P; Horimoto, A R V R; Li, Changwei et al [incl. Heikkinen, Sami; Lakka, Timo]. 2020. Gene-educational attainment interactions in a multi-ancestry genome-wide meta-analysis identify novel blood pressure loci Molecular psychiatry 2021; 26 6: 2111-2125. 2020

Naveed, Sehrish; Lakka, Timo; Haapala, Eero A. 2020. An overview on the associations between health behaviors and brain health in children and adolescents with special reference to diet quality International journal of environmental research and public health 17 3: 953. 2020

Tilles-Tirkkonen, Tanja; Aittola, Kirsikka; Männikkö, Reija; Absetz, Pilvikki; Kolehmainen, Marjukka; Schwab, Ursula; Lindström, Jaana; Lakka, Timo; Pihlajamäki, Jussi; Karhunen, Leila. 2019. Eating Competence Is Associated with Lower Prevalence of Obesity and Better Insulin Sensitivity in Finnish Adults with Increased Risk for Type 2 Diabetes: The StopDia Study Nutrients 2020; 12 1: 104. 2019

Pihlajamäki, J; Männikkö, R; Tilles-Tirkkonen, T; Karhunen, L; Kolehmainen, M; Schwab, U; Lintu, N; Paananen, J; Järvenpää, R; Harjumaa, M; Martikainen, J; Kohl, J; Poutanen, K; Ermes, M; Absetz, P; Lindström, J; Lakka, TA. 2019. Digitally supported program for type 2 diabetes risk identification and risk reduction in real-world setting: protocol for the StopDia model and randomized controlled trial Bmc public health 19: 255. 2019

Sung, Yun Ju; de Las Fuentes, Lisa; Winkler, Thomas W; Chasman, Daniel I; Bentley, Amy R; Kraja, Aldi T; Ntalla, Ioanna; Warren, Helen R; Guo, Xiuqing; Schwander, Karen; Manning, Alisa K; Brown, Michael R; Aschard, Hugues; Feitosa, Mary F; Franceschini, Nora; Lu, Yingchang; et al. (incl. Heikkinen, Sami; Kuusisto, Johanna; Laakso, Markku; Stancáková, Alena; Lakka, Timo A). 2019. A multi-ancestry genome-wide study incorporating gene-smoking interactions identifies multiple new loci for pulse pressure and mean arterial pressure Human molecular genetics 28 15: 2615-2633. 2019

Säisänen, L; Määttä, S; Julkunen, P; Niskanen, E; Kallioniemi, E; Gröhn, H; Kemppainen, S; Lakka, TA; Lintu, N; Eloranta, AM; Vanninen, R; Makkonen, I; Könönen, M. 2019. Functional and structural asymmetry in primary motor cortex in Asperger syndrome: a navigated TMS and imaging study Brain topography 32 3: 504-518. 2019

Taylor, DL; Jackson, AU; Narisu, N; Hemani, G; Erdos, MR; Chines, PS; Swift, A; Idol, J; Didion, JP; Welch, RP; Kinnunen, L; Saramies, J; Lakka, TA; Laakso, M; Tuomilehto, J; Parker, SCJ; Koistinen, HA; Davey Smith, G; Boehnke, M; Scott, LJ; et al.. 2019. Integrative analysis of gene expression, DNA methylation, physiological traits, and genetic variation in human skeletal muscle Proceedings of the National Academy of Sciences of the United States of America 116 22: 10883-10888. 2019

Viitasalo, Anna; Schnurr, Theresia M.; Pitkanen, Niina; Hollensted, Mette; Nielsen, Tenna R. H.; Pahkala, Katja; Lintu, Niina; Lind, Mads V.; Atalay, Mustafa; Frithioff-Bojsoe, Christine; Fonvig, Cilius E.; Grarup, Niels; Kahonen, Mika; Larnkjaer, Anni; Pedersen, Oluf; Holm, Jens-Christian; Michaelsen, Kim F.; Lakka, Timo A.; Lehtimaki, Terho; Raitakari, Olli; et al.. 2019. Genetic predisposition to higher body fat yet lower cardiometabolic risk in children and adolescents International journal of obesity 43: 2007-2016. 2019

Tompuri, Tuomo Tapani; Jaaskelainen, Jarmo; Lindi, Virpi; Laaksonen, David Elliot; Eloranta, Aino-Maija; Viitasalo, Anna; Laitinen, Tomi; Lakka, Limo Antero. 2019. Adiposity Criteria in Assessing Increased Cardiometabolic Risk in Prepubertal Children Frontiers in endocrinology 10: 410. 2019

Veijalainen, A; Haapala, EA; Väistö, J; Leppänen, MH; Lintu, N; Tompuri, T; Seppälä, S; Ekelund, U; Tarvainen, MP; Westgate, K; Brage, S; Lakka, TA. 2019. Associations of physical activity, sedentary time, and cardiorespiratory fitness with heart rate variability in 6- to 9-year-old children: the PANIC study European journal of applied physiology 119: 2487-2498. 2019

Viitasalo, A; Schnurr, TM; Pitkänen, N; Hollensted, M; Nielsen, TRH; Pahkala, K; Atalay, M; Lind, MV; Heikkinen, S; Frithioff-Bøjsøe, C; Fonvig, CE; Grarup, N; Kähönen, M; Carrasquilla, GD; Larnkjaer, A; Pedersen, O; Michaelsen, KF; Lakka, TA; Holm, JC; Lehtimäki, T; et al.. 2019. Abdominal adiposity and cardiometabolic risk factors in children and adolescents: a Mendelian randomization analysis American journal of clinical nutrition 110 5: 1079-1087. 2019

Warrington, NM; Beaumont, RN; Horikoshi, M; Day, FR; Helgeland, Ø; Laurin, C; Bacelis, J; Peng, S; Hao, K; Feenstra, B; Wood, AR; Mahajan, A; Tyrrell, J; Robertson, NR; Rayner, NW et al. (ncl. Joro, R; Atalay, M; Eloranta, AM; Lakka, TA). 2019. Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors Nature genetics 51 5: 804-814. 2019

Mäntyselkä, A; Haapala, EA; Lindi, V; Häkkinen, MR; Auriola, S; Jääskeläinen, J; Lakka, TA. 2019. Associations of IGF-1 and Adrenal Androgens with Cognition in Childhood Hormone research in paediatrics 91: 329-335. 2019

Määttä, S; Säisänen, L; Kallioniemi, E; Lakka, TA; Lintu, N; Haapala, EA; Koskenkorva, P; Niskanen, E; Ferreri, F; Könönen, M. 2019. Maturation changes the excitability and effective connectivity of the frontal lobe: A developmental TMS-EEG study Human brain mapping 40 8: 2320-2335. 2019

Alves, AC; De Silva, NMG; Karhunen, V; Sovio, U; Das, S; Rob Taal, H; Warrington, NM; Lewin, AM; Kaakinen, M; Cousminer, DL; Thiering, E; Timpson, NJ; Bond, TA; Lowry, E; Brown, CD; Estivill, X; Lindi, V; Bradfield, JP; Geller, F; Speed, D; et al. for BIOS Consortium [incl. Lakka, TA]. 2019. GWAS on longitudinal growth traits reveals different genetic factors influencing infant, child, and adult BMI Science advances 5 9: eaaw3095. 2019

Mäki-Opas, Tomi; Tilles-Tirkkonen, Tanja; Saari, Eveliina; Järvenpää, Riia; Lindström, Jaan; Karhunen, Leila; Kurki, Marjo; Pihlajamäki, Jussi; Niemi, Anna-Maija; Laaksonen, Linda Maria; Korkiakangas, Eveliina; Lakka, Timo; Vaarama, Marja; Laitinen, Jaana. 2019. Hyvinvoinnin ja osallisuuden edistäminen vaatii uusia vaikuttavia keinoja Policy Brief / SA 13.3.2019: 1-12. 2019

Fyysinen aktiivisuus ja ravitsemus lasten terveyden edistämisessä - tavoitteena lihavuuden, tyypin 2 diabeteksen ja valtimotautien ehkäisy. Lakka, Timo A; Talvia, Sanna; Sääkslahti, Arja; Haapala, Eero / Näkökulmia terveyteen ja sen edistämiseen. 2019. 2019

Agbaje, Andrew O; Haapala, Eero A; Lintu, Niina; Viitasalo, Anna; Vaisto, Juuso; Khan, Sohaib; Veijalainen, Aapo; Tompuri, Tuomo; Laitinen, Tomi; Lakka, Timo A. 2019. Associations of Cardiorespiratory Fitness and Adiposity With Arterial Stiffness and Arterial Dilatation Capacity in Response to a Bout of Exercise in Children Pediatric exercise science 31 2: 238-247. 2019

Middeldorp, Christel M; Felix, Janine F; Mahajan, Anubha; EArly Genetics Lifecourse Epidemiology (EAGLE) consortium; Early Growth Genetics (EGG) consortium (Incl Atalay, Mustafa; Lakka, Timo A); McCarthy, Mark I. 2019. The Early Growth Genetics (EGG) and EArly Genetics and Lifecourse Epidemiology (EAGLE) consortia: design, results and future prospects European journal of epidemiology 34 3: 279-300. 2019

Bradfield, Jonathan P; Vogelezang, Suzanne; Felix, Janine F; Chesi, Alessandra; Helgeland, Øyvind; Horikoshi, Momoko; Karhunen, Ville; Lowry, Estelle; Cousminer, Diana L; Ahluwalia, Tarunveer S; Thiering, Elisabeth; Boh, Eileen Tai-Hui; Zafarmand, Mohammad H; Vilor-Tejedor, Natalia; Wang, Carol A; Joro, Raimo; Chen, Zhanghua; Gauderman, William J; Pitkänen, Niina; Parra, Esteban J; et al. (incl. A. 2019. A trans-ancestral meta-analysis of genome-wide association studies reveals loci associated with childhood obesity Human molecular genetics 28 19: 3327-3338. 2019

de Vries, PS; Brown, MR; Bentley, AR; Sung, YJ; Winkler, TW; Ntalla, I; Schwander, K; Kraja, AT; Guo, X; Franceschini, N; Cheng, CY; Sim, X; Vojinovic, D; Huffman, JE; Musani, SK; Li, C; Feitosa, MF; Richard, MA; Noordam, R; Aschard, H; et al. (Incl. Kuusisto, Johanna; Laakso, Markku; Lakka, Timo; Heikkinen, Sami). 2019. Multi-Ancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions American journal of epidemiology 188 6: 1033-1054. 2019

Bentley, AR; Sung, YJ; Brown, MR; Winkler, TW; Kraja, AT; Ntalla, I; Schwander, K; Chasman, DI; Lim, E; Deng, X; Guo, X; Liu, J; Lu, Y; Cheng, CY; Sim, X; Vojinovic, D; Lakka, TA; Heikkinen, S; Kuusisto, J; Laakso, M; et al. (incl. Laakso, Markku; Heikkinen, Sami; Kuusisto, Johanna; Lakka, Timo; Rauramaa, Rainer). 2019. Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids Nature genetics 51 4: 636-648. 2019

Haapala, EA; Wiklund, P; Lintu, N; Tompuri, T; Väistö, J; Finni, T; Tarkka, IM; Kemppainen. T; Barker, AR; Ekelund, U; Brage, S; Lakka, TA. 2019. Cardiorespiratory Fitness, Physical Activity, and Insulin Resistance in Children Medicine and science in sports and exercise 2020; 52 5: 1144-1152. 2019

Haapala, Eero A; Lintu, Niina; Väistö, Juuso; Tompuri, Tuomo; Soininen, Sonja; Viitasalo, Anna; Eloranta, Aino-Maija; Venäläinen, Taisa; Sääkslahti, Arja; Laitinen, Tomi; Lakka, Timo A. 2019. Longitudinal Associations of Fitness, Motor Competence, and Adiposity with Cognition Medicine and science in sports and exercise 51 3: 465-471. 2019

Justice, AE; Karaderi, T; Highland, HM; Young, KL; Graff, M; Lu, Y; Turcot, V; Auer, PL; Fine, RS; Guo, X; Schurmann, C; Lempradl, A; Marouli, E; Mahajan, A; Winkler, TW; Locke, AE; Medina-Gomez, C; Esko, T; Vedantam, S; Giri, A; Lo, KS; et al. (Incl. Kuusisto, Johanna; Laakso, Markku; Lakko, Timo; Uusitupa, Matti; Vanhala, Mauno). 2019. Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution Nature genetics 51: 452-469. 2019

Kilpeläinen, TO; Bentley, AR; Noordam, R; Sung, YJ; Schwander, K; Winkler, TW; Jakupovic, H; Chasman, DI; Manning, A; Ntalla, I; Aschard, H; Brown, MR; de Las Fuentes, L; Franceschini, N; Guo, X; Vojinovic, D; Aslibekyan, S; Feitosa, MF; Kho, M; Musani, SK; et al. [Incl. Lakka, Timo; Heikkinen, Sami; Kuusisto, Johanna; Laakso, Markku]. 2019. Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity Nature communications 10 1: 376. 2019

Laukkanen, JA; Lakka, TA; Ogunjesa, BA; Kurl, S; Kunutsor, SK. 2019. Cross-country skiing and the risk of acute myocardial infarction: A prospective cohort study European journal of preventive cardiology [First Published August 19, 2019]: 1-4. 2019

Leppänen, MH; Haapala, EA; Veijalainen, A; Seppälä, S; Oliveira, RS; Lintu, N; Laitinen, T; Tarvainen, MP; Lakka, TA. 2019. Associations of cardiometabolic risk factors with heart rate variability in 6-8-year-old children: the PANIC Study Pediatric diabetes 2020; 21 2: 251-258. 2019

Medina-Gomez, C; Kemp, JP; Trajanoska, K; Luan, J; Chesi, A; Ahluwalia, TS; Mook-Kanamori, DO; Ham, A; Hartwig, FP; Evans, DS; Joro, R; Nedeljkovic, I; Zheng, HF; Zhu, K; Atalay, M; Liu, CT; Nethander, M; Broer, L; Porleifsson, G; Mullin, BH et al. [incl. Lakka, T]. 2018. Life-Course Genome-wide Association Study Meta-analysis of Total Body BMD and Assessment of Age-Specific Effects American journal of human genetics 102 1: 88-102. 2018

Väistö, Juuso; Haapala, Eero A; Viitasalo, Anna; Schnurr, Theresia M; Kilpeläinen, Tuomas O; Karjalainen, Panu; Westgate, Kate; Lakka, Hanna-Maaria; Laaksonen, David E; Ekelund, Ulf; Brage, Søren; Lakka, Timo A. 2018. Longitudinal associations of physical activity and sedentary time with cardiometabolic risk factors in children SCANDINAVIAN JOURNAL OF MEDICINE & SCIENCE IN SPORTS 2019; 29 1: 113-123. 2018

Taylor, DL; Knowles, DA; Scott, LJ; Ramirez, AH; Casale, FP; Wolford, BN; Guan, L; Varshney, A; Albanus, RD; Parker, SC; Narisu, N; Chines, PS; Erdos, MR; Welch, RP; Kinnunen, L; Saramies, J; Sundvall, J; Lakka, TA; Laakso, M; Tuomilehto, J; et al.. 2018. Interactions between genetic variation and cellular environment in skeletal muscle gene expression. PLOS ONE 13 4: e0195788. 2018

Säisänen, Laura; Julkunen, Petro; Lakka, Timo; Lindi, Virpi; Könönen, Mervi; Määttä; Sara. 2018. Development of corticospinal motor excitability and cortical silent period from mid-childhood to adulthood - a navigated TMS study. Neurophysiologie Clinique 48 2: 65-75. 2018

Soininen, Sonja; Sidoroff, Virpi; Lindi, Virpi; Mahonen, Anitta; Kröger, Liisa; Kröger, Heikki; Jääskeläinen, Jarmo; Atalay, Mustafa; Laaksonen, David E; Laitinen, Tomi; Lakka, Timo A. 2018. Body fat mass, lean body mass and associated biomarkers as determinants of bone mineral density in children 6-8 years of age - The Physical Activity and Nutrition in Children (PANIC) study Bone 108: 106-114. 2018

Soininen, Sonja; Eloranta, Aino-Maija; Viitasalo, Anna; Dion, Geneviève; Erkkilä, Arja; Sidoroff, Virpi; Lindi, Virpi; Mahonen, Anitta; Lakka, Timo A. 2018. Serum 25-Hydroxyvitamin D, Plasma Lipids, and Associated Gene Variants in Prepubertal Children JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM 103 7: 2670-2679. 2018

Savinainen, Saija; Lakka, Timo A; Vlachopoulos, Dimitris; Sääkslahti, Arja; Helajärvi, Harri; Ihalainen, Johanna K; Finni, Taija; Haapala, Eero A. 2018. Kasvu, sukupuolinen kypsyminen ja kehitys sekä niiden merkitys liikuntatieteissä Liikunta ja tiede 55 4: 23-29. 2018

Niskanen, LK; Laaksonen, DE; Nyyssonen, K; Alfthan, G; Lakka, H-M; Lakka, TA; Salonen, J. 2018. Uric acid level as a risk factor for cardiovascular and all-cause mortality in middle-aged men. A prospective cohort study (in Russian) Kardiologija v Belarusi 10 4: 440-445. 2018

Mäntyselkä, A; Lindi, V; Viitasalo, A; Eloranta, AM; Ågren, J; Väisänen, S; Voutilainen, R; Laitinen, T; Lakka, TA; Jääskeläinen, J. 2018. Associations of Dehydroepiandrosterone Sulfate with Cardiometabolic Risk Factors in Prepubertal Children JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM 103 7: 2592-2600. 2018

Häkkinen, MR; Heinosalo, T; Saarinen, N; Linnanen, T; Voutilainen, R; Lakka, T; Jääskeläinen, J; Poutanen, M; Auriola, S. 2018. Analysis by LC-MS/MS of endogenous steroids from human serum, plasma, endometrium and endometriotic tissue JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS 152: 165-172. 2018

Lintu, Niina; Joensuu, Laura; Barker, Alan; Sansum, Kate; Lakka, Timo A; Huotari, Pertti; Haapala, Eero A. 2018. Lasten ja nuorten kestävyyskunto Liikunta ja tiede 55 4: 36-43. 2018

Haapala, Eero A; Lintu, Niina; Eloranta, Aino-Maija; Venäläinen, Taisa; Poikkeus, Anna-Maija; Ahonen, Timo; Lindi, Virpi; Lakka, Timo A. 2018. Mediating effects of motor performance, cardiorespiratory fitness, physical activity, and sedentary behaviour on the associations of adiposity and other cardiometabolic risk factors with academic achievement in children Journal of Sports Sciences 36 20: 2296-2303. 2018

Ikävalko, T; Lehto, S; Lintu, N; Väistö, J; Eloranta, AM; Haapala, EA; Vierola, A; Myllykangas, R; Tuomilehto, H; Brage, S; Pahkala, R; Närhi, M; Lakka, TA. 2018. Health-related correlates of psychological well-being among girls and boys 6-8 years of age: The Physical Activity and Nutrition in Children study. Journal of Paediatrics and Child Health 54 5: 506-509. 2018

Eloranta, AM; Jääskeläinen, J; Venäläinen, T; Jalkanen, H; Kiiskinen, S; Mäntyselkä, A; Schwab, U; Lindi, V; Lakka, TA. 2018. Birth weight is associated with dietary factors at the age of 6-8 years: the Physical Activity and Nutrition in Children (PANIC) study. PUBLIC HEALTH NUTRITION 21 7: 1278-1285. 2018

Feitosa, MF; Kraja, AT; Chasman, DI; Sung, YJ; Winkler, TW; Ntalla, I; Guo, X; Franceschini, N; Cheng, CY; Sim, X; Vojinovic, D; Marten, J; Musani, SK; Li, C; Bentley, AR; Brown, MR; Schwander, K; Richard, MA; Noordam, R; Aschard, H; et al. (incl. Laakso, Markku; Heikkinen, Sami; Kuusisto, Johanna; Lakka, Timo; Yaluri, Alena). 2018. Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries PLoS ONE 13 6: e0198166. 2018

Associations of cardiorespiratory fitness and adiposity with arterial stiffness and arterial dilation capacity in response to exercise in children. Agbaje, AO; Haapala, EA; Lintu, N; Viitasalo, A; Väistö, J; Khan, S; Veijalainen, A; Tompuri, T; Laitinen, T; Lakka, TA. Pediatric exercise science. 2018. 2018

Haapala, Eero A; Paananen, Jussi; Hiltunen, Mikko; Lakka, Timo A. 2018. Associations of Genetic Susceptibility to Alzheimer's Disease with Adiposity and Cardiometabolic Risk Factors among Children in a 2-Year Follow-up Study Journal of Alzheimer's Disease 64 2: 587-595. 2018

Haworth, S; Shungin, D; van der Tas, JT; Vucic, S; Medina-Gomez, C; Yakimov, V; Feenstra, B; Shaffer, JR; Lee, MK; Standl, M; Thiering, E; Wang, C; Bønnelykke, K; Waage, J; Eyrich Jessen, L; Nørrisgaard, PE; Joro, R; Seppälä, I; Raitakari, O; Dudding, T; et al. [Incl Lakka, T; Eloranta, A-M; Vierola, A]. 2018. Consortium-based genome-wide meta-analysis for childhood dental caries traits Human molecular genetics 27 17: 3113-3127. 2018

Häkkinen, Merja R; Murtola, Teemu; Voutilainen, Raimo; Poutanen, Matti; Linnanen, Tero; Koskivuori, Johanna; Lakka, Timo; Jääskeläinen, Jarmo; Auriola, Seppo. 2018. Simultaneous analysis by LC-MS/MS of 22 ketosteroids with hydroxylamine derivatization and underivatized estradiol from human plasma, serum and prostate tissue JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS 2019; 164: 642-652. 2018

Agbaje, Andrewe O; Haapala, Eero A; Lintu, Nina; Viitasalo, Anna; Barker, Alan R; Takken, Tim; Tompuri, Tuomo; Lindi, Virpi; Lakka, Timo A. 2018. Peak oxygen uptake cut-points to identify children at increased cardiometabolic risk - The PANIC Study Scandinavian journal of medicine and science in sports 2019; 29 1: 16-24. 2018

Länsimies H, Halkoaho A, Pietilä A-M, Lintu N, Kangasniemi M, Eloranta A-M, Viitasalo A, Lakka TA. 2017. Is there a duty to participate in a health research? A viewpoint of children 6-8 years of age and their parents. International Diabetes Nursing 13 1-3: 49-54. 2017

Warrington NM, Richmond R, Fenstra B, Myhre R, Gaillard R, Paternoster L, Wang CA, Beaumont RN, Das S, Murcia M, Barton SJ, Espinosa A, Thiering E, Atalay M, Pitkänen N, Ntalla I, Jonsson AE, Freathy R, Karhunen V, Tiesler CMT et al. for the Early Growth Genetics (EGG) consortium. 2017. Maternal and fetal genetic contribution to gestational weight gain. INTERNATIONAL JOURNAL OF OBESITY 42 4: 775-784. 2017

Vierola A, Suominen AL, Eloranta AM, Lintu N, Ikävalko T, Närhi M, Lakka T. 2017. Determinants for craniofacial pains in children 6-8 years of age: the PANIC study. ACTA ODONTOLOGICA SCANDINAVICA 75 6: 453-460. 2017

Turcot V, Lu Y, Highland HM, Schurmann C, Justice AE, Fine RS, Bradfield JP, Esko T, Giri A, Graff M, Guo X, Hendricks AE, Karaderi T, Lempradl A, Locke AE, Mahajan A, Marouli E, Sivapalaratnam S, Young KL, Alfred T et al. (incl. Laakso Markku, Lakka Timo, Uusitupa Matti). 2017. Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity NATURE GENETICS 50; 2018 1: 26-41. 2017

Tompuri, Tuomo; Lintu, Niina; Laitinen, Tomi; Lakka, Timo A. 2017. Relation of oxygen uptake to work rate in prepubertal healthy children - reference for VO2/W-slope and effect on cardiorespiratory fitness assessment. CLINICAL PHYSIOLOGY AND FUNCTIONAL IMAGING 2018; 38 4: 645-651. 2017

Schnurr TM, Viitasalo A, Eloranta AM, Damsgaard CT, Mahendran Y, Have CT, Väistö J, Hjorth MF, Christensen LB, Brage S, Atalay M, Lyytikäinen LP, Lindi V, Lakka T, Michaelsen KF, Kilpeläinen TO, Hansen T. 2017. Genetic predisposition to adiposity is associated with increased objectively assessed sedentary time in young children. INTERNATIONAL JOURNAL OF OBESITY 42: 111-114. 2017

Määttä S, Könönen M, Kallioniemi E, Lakka T, Lintu N, Lindi V, Ferreri F, Ponzo D, Säisänen L. 2017. Development of cortical motor circuits between childhood and adulthood: A navigated TMS-HdEEG study. HUMAN BRAIN MAPPING 38 5: 2599-2615. 2017

Mäntyselkä A, Jääskeläinen J, Eloranta AM, Väistö J, Voutilainen R, Ong K, Brage S, Lakka TA, Lindi V. 2017. Associations of lifestyle factors with serum dehydroepiandrosterone sulfate and insulin-like growth factor-1 concentration in prepubertal children Clinical endocrinology 2018; 88 2: 234-242. 2017

Marouli Eirini, Graff Mariaelisa, Medina-Gomez Carolina, Sin Lo Ken, Wood Andrew R, Kjaer Troels R, Fine Rebecca S, Lu Yingchang, Schurmann Claudia, Highland Heather M, Rüeger Sina, Thorleifsson Gudmar, Justice Anne E, Lamparter David, Stirrups Kathleen E, Turcot Valérie, Young Kristin L, Winkler Thomas W, Esko Tõnu, Karaderi Tugce et al. (incl Kuusisto Johanna, Laakso Markku, Lakka Timo A). 2017. Rare and low-frequency coding variants alter human adult height. Nature 542: 186-190. 2017

Manning A, Highland HM, Gasser J, Sim X, Tukiainen T, Fontanillas P, Grarup N, Rivas MA, Mahajan A, Locke AE, Cingolani P, Pers TH, Viñuela A, Brown AA, Wu Y, Flannick J, Fuchsberger C, Gamazon ER, Gaulton KJ, Im HK et al. (incl. Lakka Timo, Kuulasmaa Teemu, Laakso Markku, Uusitupa Matti). 2017. A Low-Frequency Inactivating AKT2 Variant Enriched in the Finnish Population Is Associated With Fasting Insulin Levels and Type 2 Diabetes Risk. DIABETES (NY) 66 7: 2019-2032. 2017

Liu DJ, Peloso GM, Yu H, Butterworth AS, Wang X, Mahajan A, Saleheen D, Emdin C, Alam D, Alves AC, Amouyel P, Di Angelantonio E, Arveiler D, Assimes TL, Auer PL, Baber U, Ballantyne CM, Bang LE, Benn M, Bis JC et al.. 2017. Exome-wide association study of plasma lipids in >300,000 individuals. NATURE GENETICS 49 12: 1758-1766. 2017

Lampinen Eeva-Kaarina, Eloranta Aino-Maija, Haapala Eero A, Lindi Virpi, Väistö Juuso, Lintu Niina, Karjalainen Panu, Kukkonen-Harjula Katriina, Laaksonen David, Lakka Timo A. 2017. Physical activity, sedentary behaviour, and socioeconomic status among Finnish girls and boys aged 6 - 8 years. European Journal of Sport Science 17 4: 462-472. 2017

Kraja Aldi T, Cook James P, Warren Helen R, Surendran Praveen, Liu Chunyu, Evangelou Evangelos, Mannig Alisa K, Grarup Niels, Drenos Fotios, Sim Xueling, Smith Albert Vernon, Amin Najaf, Blakemore Alexandra I F, Bork-Jensen Jette, Brandslund Ivan, Farmaki Aliki-Eleni, Fava Cristiano, Ferreira Teresa, Herzig Karl-Heinz, Giri Ayush et al.. 2017. New Blood Pressure-Associated Loci Identified in Meta-Analyses of 475 000 Individuals. Circulation: Cardiovascular Genetics 10 5: e001778. 2017

Justice Anne E, Winkler Thomas W, Feitosa Mary F, Graff Misa, Fisher Virginia A, Young Kristin, Barata Llilda, Deng Xuan, Czajkowski Jacek, Hadley David, Ngwa Julius S, Ahluwalia Tarunveer S, Chu Audrey Y, Heard-Costa Nancy L, Lim Elise, Perez Jeremiah, Eicher John D, Kutalik Zoltan, Xue Luting, Mahajan Anubha et al.. 2017. Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits. Nature Communications 8: 14977. 2017

Jalkanen H, Lindi V, Schwab U, Kiiskinen S, Venäläinen T, Karhunen L, Lakka TA, Eloranta AM. 2017. Eating behaviour is associated with eating frequency and food consumption in 6-8 year-old children: The Physical Activity and Nutrition in Children (PANIC) study. APPETITE 114: 28-37. 2017

Ikävalko, T; Närhi, M; Eloranta, AM; Lintu, N; Myllykangas, R; Vierola, A; Tuomilehto, H; Lakka, T; Pahkala, R. 2017. Predictors of sleep disordered breathing in children: the PANIC study European Journal of Orthodontics 2018; 40 3: 268-272. 2017

Hagnäs, MJ; Lakka, TA; Mäkikallio, TH; Kurl, S; Savonen, K; Rauramaa, R; Laukkanen, JA. 2017. High Leisure-Time Physical Activity Is Associated With Reduced Risk of Sudden Cardiac Death Among Men With Low Cardiorespiratory Fitness. Canadian Journal of Cardiology 2018; 34 3: 288-294. 2017

Haapala Eero, Väistö Juuso, Veijalainen Aapo, Lintu Niina, Wiklund P,etri Westgate Kate, Ekelund Ulf, Lindi Virpi, Brage Soren, Lakka Timo A. 2017. Associations of Objectively Measured Physical Activity and Sedentary Time With Arterial Stiffness in Pre-pubertal Children. PEDIATRIC EXERCISE SCIENCE 29 3: 326-335. 2017

Haapala Eero A, Väistö Juuso, Lintu Niina, Eloranta Aino-Maija, Lindi Virpi, Lakka Timo A. 2017. Vähäinen fyysinen aktiivisuus ja runsas fyysinen passiivisuus ovat yhteydessä 6-8-vuotiaiden lasten ylipainoon. LIIKUNTA JA TIEDE 54 2-3: 106-112. 2017

Graff M, Scott RA, Justice AE, Young KL, Feitosa MF, Barata L, Winkler TW, Chu AY, Mahajan A, Hadley D, Xue L, Workalemahu T, Heard-Costa NL, den Hoed M, Ahluwalia TS, Qi Q, Ngwa JS, Renström F, Quaye L, Eicher JD et al.. 2017. Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults. PLOS GENETICS [ONLINE) 13 4: e1006528. 2017

Venäläinen Taisa M, Viitasalo Anna M, Schwab Ursula S, Eloranta Aino-Maija, Haapala Eero A, Jalkanen Henna P, de Mello Vanessa DF, Laaksonen David E, Lindi Virpi I, Ågren Jyrki J, Lakka Timo A. 2016. Effect of a 2-y dietary and physical activity intervention on plasma fatty acid composition and estimated desaturase and elongase activities in children: the Physical Activity and Nutrition in Children Study. AMERICAN JOURNAL OF CLINICAL NUTRITION 104 4: 964-972. 2016

Soininen Sonja, Eloranta Aino-Maija, Lindi Virpi, Venäläinen Taisa, Zaproudina Nina, Mahonen Anitta, Lakka Timo A. 2016. Determinants of serum 25-hydroxyvitamin D concentration in Finnish children: the Physical Activity and Nutrition in Children (PANIC) study. BRITISH JOURNAL OF NUTRITION 115 6: 1080-1091. 2016

Surendran P, Drenos F, Young R, Warren H, Cook JP, Manning AK, Grarup N, Sim X, Barnes DR, Witkowska K, Staley JR, Tragante V, Tukiainen T, Yaghootkar H, Masca N, Freitag DF, Ferreira T, Giannakopoulou O, Tinker A, Harakalova M et al. 2016. Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension. NATURE GENETICS 48: 1151-1161. 2016

Tieteelliset perusteet varhaisvuosien fyysisen aktiivisuuden suosituksille. Sääkslahti Arja, Muuronen Kaisu, Haapala Eero, Pulakka Anna, Haapala Henna, Lakka Timo A, Laukkanen Arto, Määttä Suvi, Reunamo Jyrki, Roos Eva, Soini Anne, Mäki Päivi, Iivonen Susanna, Asunta Piritta, Viholainen Helena, Ahonen Timo, Rintala Pauli, Cantell Marja, Kyhälä Anna-Liisa. 2016 2016

Tompuri Tuomo T, Lintu Niina, Soininen Sonja, Laitinen Tomi, Lakka Timo A. 2016. Comparison between parameters from maximal cycle ergometer test first without respiratory gas analysis and thereafter with respiratory gas analysis among healthy prepubertal children. APPLIED PHYSIOLOGY, NUTRITION AND METABOLISM 41 6: 624-630. 2016

Viitasalo Anna, Pihlajamäki Jussi, Paananen Jussi, Atalay Mustafa, Lindi Virpi, Lakka Timo A. 2016. Associations of TM6SF2 167K allele with liver enzymes and lipid profile in children: the PANIC Study. PEDIATRIC RESEARCH 79 5: 684-688. 2016

Vierola Anu, Suominen Anna Liisa, Lindi Virpi, Viitasalo Anna, Ikävalko Tiina, Lintu Niina, Väistö Juuso, Kellokoski Jari, Närhi Matti, Lakka Timo A. 2016. Associations of Sedentary Behavior, Physical Activity, Cardiorespiratory Fitness, and Body Fat Content With Pain Conditions in Children: The Physical Activity and Nutrition in Children Study. JOURNAL OF PAIN 17 7: 845-853. 2016

Viitasalo A, Eloranta A-M, Atalay M, Romeo S, Pihlajamäki J, Lakka TA. 2016. Association of MBOAT7 gene variant with plasma ALT levels in children: The PANIC study. PEDIATRIC RESEARCH 80 5: 651-655. 2016

Viitasalo Anna, Eloranta Aino-Maija, Lintu Niina, Väistö Juuso, Venäläinen Taisa, Kiiskinen Sanna, Karjalainen Panu, Peltola Jaana, Lampinen Eeva-Kaarina, Haapala Eero A, Paananen Jussi, Schwab Ursula, Lindi Virpi, Lakka Timo A. 2016. The Effects of a 2-year Individualized and Family-based Lifestyle Intervention on Physical Activity, Sedentary Behavior and Diet in Children. PREVENTIVE MEDICINE 87: 81-88. 2016

Scott Laura J, Erdos Michael R, Huyghe Jeroen R, Welch Ryan P, Beck Andrew T, Wolford Brooke N, Chines Peter S, Didion John P, Narisu Narisu, Stringham Heather N, Taylor D Leeland, Jackson Anne U, Vadlamudi Swarooparani, Bonnycastle Bonny M, Kinnunen Leena, Saramies Jouko, Sundvall Jouko, D'Oliveira Albanus Ricardo, Kiseleva Anna, Hensley John et al (inc. LakkaTimo A, Laakso Markku). 2016. The genetic regulatory signature of type 2 diabetes in human skeletal muscle Nature Communications 7: 11764. 2016

Winkler Thomas W, Justice Anne E, Graff Mariaelisa, Barata Llilda, Feitosa Mary F, Chu Su, Czajkowski Jacek, Esko Tõnu, Fall Tove, Kilpeläinen Tuomas O, Lu Yingchang, Mägi Reedik, Mihailov Evelin, Pers Tune H, Rüeger Sina, Teumer Alexander, Ehret Georg B, Ferreira Teresa, Heard-Costa Nancy L, Karjalainen Juha et al. 2016. Correction: The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study. PLOS GENETICS [ONLINE) 12 6: e1006166. 2016

Soininen Sonja, Eloranta Aino-Maija, Lindi Virpi, Lakka Timo A. 2016. Response: food fortification as a means to increase vitamin D intake. BRITISH JOURNAL OF NUTRITION 116 6: 1134-1135. 2016

Ehret GB, Ferreira T, Chasman DI, Jackson AU, Schmidt EM, Johnson T, Thorleifsson G, Luan J, Donnelly LA, Kanoni S, Petersen AK, Pihur V, Strawbridge RJ, Shungin D, Hughes MF, Meirelles O, Kaakinen M, Bouatia-Naji N, Kristiansson K, Shah S et al.. 2016. The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals. NATURE GENETICS 48 10: 1171-1184. 2016

Ried JS, Jeff M J, Chu AY, Bragg-Gresham JL, van Dongen J, Huffman JE, Ahluwalia TS, Cadby G, Eklund N, Eriksson J, Esko T, Feitosa MF, Goel A, Gorski M, Hayward C, Heard-Costa NL, Jackson AU, Jokinen E, Kanoni S, Kristiansson K et al. 2016. A principal component meta-analysis on multiple anthropometric traits identifies novel loci for body shape. Nature Communications 7: 13357. 2016

Haapala EA, Viitasalo A, Venäläinen T, Eloranta AM, Ågren J, Lindi V, Lakka TA. 2016. Plasma polyunsaturated fatty acids are directly associated with cognition in overweight children but not in normal weight children. ACTA PAEDIATRICA 105 12: 1502-1507. 2016

Aarela Linnea, Nurminen Samuli, Kivela Laura, Huhtala Heini, Maki Markku, Viitasalo Anna, Kaukinen Katri, Lakka Timo, Kurppa Kalle. 2016. Prevalence and associated factors of abnormal liver values in children with celiac disease. DIGESTIVE AND LIVER DISEASE 48 9: 1023-1029. 2016

Lintu Niina, Savonen Kai, Viitasalo Anna, Tompuri Timo, Paananen Jussi, Tarvainen Mika P, Lakka Timo. 2016. Determinants of cardiorespiratory fitness in a population sample of girls and boys aged 6-8 years. JOURNAL OF PHYSICAL ACTIVITY AND HEALTH [epub ahead of print]: 1-22. 2016

Eloranta Aino-Maija, Schwab Ursula, Venäläinen Taisa, Kiiskinen Sanna, Lakka HM, Laaksonen David E, Lakka Timo A, Lindi Virpi. 2016. Dietary quality indices in relation to cardiometabolic risk among Finnish children aged 6-8 years - The PANIC study. NUTRITION, METABOLISM AND CARDIOVASCULAR DISEASES 26 9: 833-841. 2016

Eloranta Aino-Maija, Venäläinen Taisa, Soininen Sonja, Jalkanen Henna, Kiiskinen Sanna, Schwab Ursula, Lakka Timo A, Lindi Virpi. 2016. Food sources of energy and nutrients in Finnish girls and boys 6-8 years of age - the PANIC study. FOOD & NUTRITION RESEARCH 60: 32444. 2016

Collings Paul J, Westgate Kate, Väistö Juuso, Wijndaele Katrien, Atkin Andrew J, Haapala Eero A, Lintu Niina, Laitinen Tomi, Ekelund Ulf, Brage Soren, Lakka Timo A. 2016. Cross-sectional associations of objectively-measured physical activity and sedentary time with body composition and cardiorespiratory fitness in mid-childhood: the PANIC study. SPORTS MEDICINE [Epub ahead of print 24 Aug 2016]: 1-12. 2016

Haapala EA, Väistö J, Lintu N, Westgate K, Ekelund U, Poikkeus A-M, Brage S, Lakka TA. 2016. Physical activity and sedentary time in relation to academicachievement in children. Journal of Science and Medicine in Sport 2017; 20 6: 583-589. 2016

Haapala Eero A, Eloranta Aino-Maija, Venäläinen Taisa, Jalkanen Henna, Poikkeus Anna-Maija, Ahonen Timo, Lindi Virpi, Lakka Timo A. 2016. Diet quality and academic achievement: a prospective study among primary school children. EUROPEAN JOURNAL OF NUTRITION 56 7: 2299-2308. 2016

Haapala Eero A, Vaisto, Juuso, Lintu Niina, Tompuri Tuomo, Brage Soren, Westgate Kate, Ekelund Ulf, Lampinen Eeva-Kaarina, Saakslahti Arja, Lindi Virpi, Lakka Timo A. 2016. Adiposity, physical activity and neuromuscular performance in children. Journal of Sports Sciences 34 18: 1699-706. 2016

Hagnäs MJ, Lakka TA, Kurl S, Rauramaa R, Mäkikallio TH, Savonen K, Laukkanen JA. 2016. Cardiorespiratory fitness and exercise-induced ST segment depression in assessing the risk of sudden cardiac death in men. Heart 103 5: 383-389. 2016

Hinney A, Kesselmeier M, Jall S, Volckmar AL, Föcker M, Antel J, Heid IM, Winkler TW, Grant SF, Guo Y, Bergen AW, Kaye W, Berrettini W, Hakonarson H, Herpertz-Dahlmann B, de Zwaan M, Herzog W, Ehrlich S, Zipfel S, Egberts KM et al., GCAN, WTCCC3, EGG, GIANT, Price Foundation Collaborative Group, Children's Hospital of Philadelphia/Price Foundation. 2016. Evidence for three genetic loci involved in both anorexia nervosa risk and variation of body mass index. MOLECULAR PSYCHIATRY 2017; 22: 192-201. 2016

Horikoshi M, Beaumont RN, Day FR, Warrington NM, Kooijman MN, Fernandez-Tajes J, Feenstra B, van Zuydam NR, Gaulton KJ, Grarup N, Bradfield JP, Strachan DP, Li-Gao R, Ahluwalia TS, Kreiner E, Rueedi R, Lyytikäinen LP, Cousminer DL, Wu Y, Thiering E et al.. 2016. Genome-wide associations for birth weight and correlations with adult disease. NATURE (LONDON) [Epub ahead of print 28 Sep 2016]: 1-20. 2016

Zaproudina Nina, Närhi Matti, Veijalainen Aapo, Laitinen Tomi, Lakka Timo A. 2015. Finger skin temperatures in 8- to 11-year-old children: determinants including physical characteristics and seasonal variation. The Physical Activity an Nutrition in Children (PANIC) Study. EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY [epub ahead of print 26 Nov 2015]: 1-9. 2015

Pers Tune H, Karjalainen Juha M, Chan Yingleong, Westra Harm-Jan, Wood Andrew R, Yang Jian, Lui Julian C, Vedantam Sailaja, Gustafsson Stefan, Esko Tonu, Frayling Tim, Speliotes Elizabeth K, Genetic Investigation of ANthropometric Traits (GIANT) Consortium (incl. Johanna Kuusisto, Markku Laakso, Timo Lakka, Matti Uusitupa), Boehnke Michael, Raychaudhuri Soumya, Fehrmann Rudolf SN, Hirschhorn Joel . 2015. Biological interpretation of genome-wide association studies using predicted gene functions. Nature Communications 6: 5890. 2015

Viitasalo Anna, Mustafa Atalay, Pihlajamäki Jussi, Jääskeläinen Jarmo, Korkmaz Ayhan, Kaminska Dorota, Lindi Virpi, Lakka Timo A.. 2015. The 148 M allele of the PNPLA3 is associated with plasma irisin levels in a population sample of Caucasian children: The PANIC Study. METABOLISM 64 7: 793-796. 2015

Viitasalo A, Ågren J, Venäläinen T, Pihlajamäki J, Jääskeläinen J, Korkmaz A, Atalay M, Lakka TA. 2015. Association of plasma fatty acid composition with plasma irisin levels in normal weight and overweight/obese children. PEDIATRIC OBESITY 2015; 11 4: 299-305. 2015

Venäläinen Taisa, Ågren Jyrki, Schwab Ursula, de Mello Vanessa D, Eloranta Aino-Maija, Laaksonen David E, Lindi Virpi, Lakka Timo A. 2015. Cross-sectional associations of plasma fatty acid composition and estimated desaturase and elongase activities with cardiometabolic risk in Finnish children - The PANIC study. Journal of Clinical Lipidology 2016; 10 1: 82-91. 2015

Veijalainen A, Tompuri T, Haapala EA, Viitasalo , Lintu N, Väistö J, Laitinen T, Lindi V, Lakka TA. 2015. Associations of cardiorespiratory fitness, physical activity, and adiposity with arterial stiffness in children. SCANDINAVIAN JOURNAL OF MEDICINE & SCIENCE IN SPORTS [epub ahead of print 29 Jul 2015]: -. 2015

Säisänen Laura, Könönen Mervi, Anttonen Meri, Niskanen Eini, Lintu Niina, Lindi Virpi, Lakka Timo, Vanninen Ritva, Makkonen Ismo, Julkunen Petro, Määttä Sara. 2015. Motor cortical alterations in children with Asperger's syndrome studied with navigated TMS. Teoksessa: I Rektor (toim.), The 15th European congress on clinical neurophysiology. 2015

Shungin Dmitry, Winkler Thomas W, Croteau-Chonka Damien C, Ferreira Teresa, Locke Adam E, Mägi Reedik, Strawbridge Rona J, Pers Tune H, Fischer Krista, Justice Anne E, Workalemahu Tsegaselassie, Wu Joseph MW, Buchkovich Martin L, Heard-Costa Nancy L, Roman Tamara S, Drong Alexander W, Song Ci, Gustafsson Stefan, Day Felix R, Esko Tonu et al. 2015. New genetic loci link adipose and insulin biology to body fat distribution. NATURE (LONDON) 518 7538: 187-196. 2015

Qi Qibin, Downer Mary K, Kilpeläinen Tuomas O, Taal H Rob, Barton Sheila J, Ntalla Ioanna, Standl Marie, Boraska Vesna, Huikari Ville, Kiefte-de Jong Jessica C, Körner Antje, Lakka Timo A, Liu Gaifen, Magnusson Jessica, Okuda Masayuki, Raitakari Olli, Richmond Rebecca, Scott Robert A, Bailey Mark ES, Scheuermann Kathrin et al. 2015. Dietary Intake, FTO Genetic Variants, and Adiposity: A Combined Analysis of Over 16,000 Children and Adolescents. DIABETES (NY) 64 7: 2467-2476. 2015

Winkler Thomas W, Justice Anne E, Graff Mariaelisa, Barata Llilda, Feitosa Mary F, Chu Su, Czajkowski Jacek, Esko Tõnu, Fall Tove, Kilpeläinen Tuomas O, Lu Yingchang, Mägi Reedik, Mihailov Evelin, Pers Tune H, Rüeger Sina, Teumer Alexander, Ehret Georg B, Ferreira Teresa, Heard-Costa Nancy L, Karjalainen Juha et al. 2015. The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study. PLOS GENETICS [ONLINE) 11 10: e1005378. 2015

Locke Adam E, Kahali Bratati, Berndt Sonja I, Justice Anne E, Pers Tune H, Day Felix R, Powell Corey, Vedantam Sailaja, Buchkovich Martin L, Yang Jian, Croteau-Chonka Damien C, Esko Tonu, Fall Tove, Ferreira Teresa, Gustafsson Stefan, Kutalik Zoltán, Luan Jian'an, Mägi Reedik, Randall Joshua C, Winkler Thomas W et al. 2015. Genetic studies of body mass index yield new insights for obesity biology. NATURE (LONDON) 518 7538: 197-206. 2015

Haapala Eero A, Eloranta Aino-Maija, Venäläinen Taiisa, Schwab Ursula, Lindi Virpi, Lakka Timo A. 2015. Associations of diet quality with cognition in children - the Physical Activity and Nutrition in Children Study. BRITISH JOURNAL OF NUTRITION 114 07: 1080-1087. 2015

Krachler Benno, Savonen Kai, Lakka Timo. 2015. Obesity is an important source of bias in the assessment of cardiorespiratory fitness. AMERICAN HEART JOURNAL 170 5: e7-e8. 2015

Felix Janine F, Bradfield Jonathan P, Monnereau Claire, van der Valk Ralf JP, Stergiakouli Evie, Chesi Alessandra, Gaillard Romy, Feenstra Bjarke, Thiering Elisabeth, Kreiner-Møller Eskil, Mahajan Anubha, Pitkänen Niina, Joro Raimo, Cavadino Alana, Huikari Ville, Franks Steve, Groen-Blokhuis Maria M, Cousminer Diana L, Marsh Julie A, Lehtimäki Terho et al.; Early Growth Genetics (EGG) Consortium; . 2015. Genome-wide association analysis identifies three new susceptibility loci for childhood body mass index. HUMAN MOLECULAR GENETICS (2016) 25 2: 389-403. 2015

Gaulton KJ, Ferreira T, Lee Y, Raimondo A, Mägi R, Reschen ME, Mahajan A, Locke A, William Rayner N, Robertson N, Scott RA, Prokopenko I, Scott LJ, Green T, Sparso T, Thuillier D, Yengo L, Grallert H, Wahl S, Frånberg M et al.. 2015. Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci. NATURE GENETICS 47: 1415-1425. 2015

Eskeli Ritva, Lösönen Matias, Ikävalko Tiina, Myllykangas Riitta, Lakka Timo, Laine-Alava Maija T. 2015. Secular trends affect timing of emergence of permanent teeth. ANGLE ORTHODONTIST Published Online: April 29, 2015: 6 p. 2015

Haapala Eero A, Lintu Niina, Väistö Juuso, Robinson Leah E, Viitasalo Anna, Lindi Virpi, Lakka Timo A. 2015. Associations of Physical Performance and Adiposity with Cognition in Children. MEDICINE AND SCIENCE IN SPORTS AND EXERCISE 47 10: 2166-2174. 2015

Hagnas Magnus J., Kurl Sudhir, Rauramaa Rainer, Lakka Timo A., Makikallio Timo H., Savonen Kai, Laukkanen Jari A.. 2015. The value of cardiorespiratory fitness and exercise-induced ST segment depression in predicting death from coronary heart disease. INTERNATIONAL JOURNAL OF CARDIOLOGY 196: 31-33. 2015

Ikävalko Tiina, Närhi Matti, Lakka Timo, Myllykangas Riitta, Tuomilehto Henri, Vierola Anu, Pahkala Riitta. 2015. Lateral facial profile may reveal the risk for sleep disordered breathing in children - The PANIC-study. ACTA ODONTOLOGICA SCANDINAVICA online April 20, 2015: 6 p. 2015

Krachler Benno, Savonen Kai, Komulainen Pirjo, Hassinen Maija, Lakka Timo A, Rauramaa Rainer. 2015. VO2max/kg is expected to be lower in obese individuals!. INTERNATIONAL JOURNAL OF CARDIOLOGY 189: 234. 2015

Krachler Benno, Savonen Kai, Komulainen Pirjo, Hassinen Maija, Lakka Timo A., Rauramaa Rainer. 2015. Cardiopulmonary fitness is a function of lean mass, not total body weight: The DR's EXTRA study. European Journal of Preventive Cardiology 22 9: 1171-1179. 2015

Rahmioglu Nilufer, Macgregor Stuart, Drong Alexander W, Hedman Åsa K, Harris Holly R, Randall Joshua C, Prokopenko Inga, The International EndoGene Consortium (IEC), The GIANT Consortium, Nyholt Dale R, Morris Andrew P, Montgomery Grant W, Missmer Stacey A, Lindgren Cecilia M, Zondervan Krina T. 2014. Genome-wide Enrichment Analysis between Endometriosis and Obesity-related Traits Reveals Novel Susceptibility Loci. HUMAN MOLECULAR GENETICS Epub ahead of print: -. 2014

Wood Andrew R, Esko Tonu, Yang Jian, Vedantam Sailaja, Pers Tune H, Gustafsson Stefan, Chu Audrey Y, Estrada Karol, Luan Jian'an, Kutalik Zoltán, Amin Najaf, Buchkovich Martin L, Croteau-Chonka Damien C, Day Felix R, Duan Yanan, Fall Tove, Fehrmann Rudolf, Ferreira Teresa, Jackson Anne U, Karjalainen Juha et.al.. 2014. Defining the role of common variation in the genomic and biological architecture of adult human height. NATURE GENETICS 46 11: 1173-86. 2014

Väistö J, Eloranta A-M, Viitasalo A, Tompuri T, Lintu N, Karjalainen P, Lampinen E-K, Ågren J, Laaksonen DE, Lakka H-M, Lindi V, Lakka TA. 2014. Physical activity and sedentary behaviour in relation to cardiometabolic risk in children: cross-sectional findings from the Physical Activity and Nutrition in Children (PANIC) Study. INTERNATIONAL JOURNAL OF BEHAVIORAL NUTRITION AND PHYSICAL ACTIVITY 11 1: 55. 2014

Viitasalo Anna, Lakka Timo A, Laaksonen David E, Savonen Kai, Lakka Hanna-Maaria, Hassinen Maija, Komulainen Pirjo, Tompuri Tuomo, Kurl Sudhir, Laukkanen Jari A, Rauramaa Rainer. 2014. Validation of metabolic syndrome score by confirmatory factor analysis in children and adults and prediction of cardiometabolic outcomes in adults. DIABETOLOGIA Epub ahead of print: -. 2014

Viitasalo A, Pihlajamaki J, Lindi V, Atalay M, Kaminska D, Joro R, Lakka TA. 2014. Associations of I148M variant in PNPLA3 gene with plasma ALT levels during 2-year follow-up in normal weight and overweight children: the PANIC Study. PEDIATRIC OBESITY - -[Epub ahead of print]. 2014

Venäläinen Taisa, Schwab Ursula, Ågren Jyrki, de Mello Vanessa, Lindi Virpi, Eloranta Aino-Maija, Kiiskinen Sanna, Laaksonen David, Lakka Timo A. 2014. Cross-Sectional Associations of Food Consumption with Plasma Fatty Acid Composition and Estimated Desaturase Activities in Finnish Children. LIPIDS 49 5: 467-479. 2014

van der Valk Ralf JP, Kreiner-Moller Eskil, Kooijman Marjolein N, Guxens Mònica, Stergiakouli Evangelia, Sääf Annika, Bradfield Jonatan P, Geller Frank, Geoffrey Hayes M, Cousminer Diana L, Körner Antje, Thiering Elisabeth, Curtin John A, Myhre Ronny, Huikari Ville, Joro Raimo, Kerkhof Marjan, Warrington Nicole M, Pitkänen Niina, Ntalla Ioanna et. al.. 2014. A novel common variant in DCST2 is associated with length in early life and height in adulthood. HUMAN MOLECULAR GENETICS Epub ahead of print: -. 2014

Tompuri Tuomo, Lintu Niina, Savonen Kai, Laitinen Tomi, Laaksonen David, Jääskeläinen Jarmo, Lakka Timo A. 2014. Measures of cardiorespiratory fitness in relation to measures of body size and composition among children. CLINICAL PHYSIOLOGY AND FUNCTIONAL IMAGING Epub ahead of print: -. 2014

Seppälä S, Laitinen T, Tarvainen MP, Tompuri T, Veijalainen A, Savonen K, Lakka T. 2014. Normal values for heart rate variability parameters in children 6-8 years of age: The PANIC study. CLINICAL PHYSIOLOGY AND FUNCTIONAL IMAGING 34(4): 290-296. 2014

Lintu Niina, Viitasalo Anna, Tompuri Tuomo, Veijalainen Aapo, Hakulinen Mikko, Laitinen Tomi, Savonen Kai, Lakka Timo A. 2014. Cardiorespiratory fitness, respiratory function and hemodynamic responses to maximal cycle ergometer exercise test in girls and boys aged 9-11 years: the PANIC Study. EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY Epub ahead of print: -. 2014

Prokopenko Inga, Poon Wenny, Mägi Reedik, Prasad BR, Salehi S Albert, Almgren Peter, Osmark Peter, Bouatia-Naji Nabila, Wierup Nils, Fall Tove, Stancáková Alena, Barker Adam, Lagou Vasiliki, Osmond Clive, Xie Weijia, Lahti Jari, Jackson Anne U, Cheng Yu-Ching, Liu Jie, O'Connell Jeffrey R et al. (including Kuusisto Johanna, Laakso Markku, Lakka Timo). 2014. A Central Role for GRB10 in Regulation of Islet Function in Man. PLOS GENETICS [ONLINE) 10 4: e1004235. 2014

Mäntyselkä Aino, Jääskeläinen Jarmo, Lindi Virpi, Viitasalo Anna, Tompuri Tuomo, Voutilainen Raimo, Lakka Timo A. 2014. The presentation of adrenarche is sexually dimorphic and modified by body adiposity. JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM 99 10: 3889-3894. 2014

Mäntyselkä Aino, Jääskeläinen Jarmo, Lindi Virpi, Viitasalo Anna, Tompuri Tuomo, Voutilainen Raimo, Lakka Timo A. 2014. Ennenaikaisen adrenarken sukupuolierot saattavat johtua erilaisesta kehon rasvakoostumuksesta. DUODECIM 130: 101. 2014

HPS2-THRIVE Collaborative Group, Landray MJ, Haynes R, Hopewell JC, Parish S, Aung T, Tomson J, Wallendszus K, Craig M, Jiang L, Collins R, Armitage J. 2014. Effects of extended-release niacin with laropiprant in high-risk patients. NEW ENGLAND JOURNAL OF MEDICINE 371 3: 203-212. 2014

Hoggart Clive J, Venturini Giulia, Mangino Massimo, Gomez Felicia, Ascari Giulia, Zhao Jing Hua, Teumer Alexander, Winkler Thomas W, Tšernikova Natalia, Luan Jian'an, Mihailov Evelin, Ehret Georg B, Zhang Weihua, Lamparter David, Esko Tõnu, Macé Aurelian, Rüeger Sina, Bochud Pierre-Yves, Barcella Matteo, Dauvilliers Yves et al (including Atalay Mustafa, Kuusisto Johanna, Lakka Timo, Yaluri Alena, . 2014. Novel approach identifies SNPs in SLC2A10 and KCNK9 with evidence for parent-of-origin effect on body mass index. PLOS GENETICS [ONLINE) 10 7: e1004508. 2014

Hakola Leena, Savonen Kai, Komulainen Pirjo, Hassinen Maija, Rauramaa Rainer, Lakka Timo A. 2014. Moderators of Maintained Increase in Aerobic Exercise Among Aging Men and Women in a 4-year Randomized Controlled Trial: The DR's EXTRA Study. JOURNAL OF PHYSICAL ACTIVITY AND HEALTH -: -. 2014

Hakola Leena, Hassinen Maija, Komulainen Pirjo, Lakka Timo A, Savonen Kai, Rauramaa Rainer. 2014. Correlates of Low Physical Activity Levels in Aging Men and Women: The DR's EXTRA Study. JOURNAL OF AGING AND PHYSICAL ACTIVITY Epub ahead of print: -. 2014

Haapala Eero A, Tompuri Tuomo, Lintu Niina, Laitinen Tomi, Lindi Virpi, Lakka Timo A. 2014. Associations Of Cardiovascular Fitness, Motor Performance And Adiposity With Cognition In Children. 46(5):169. 2014

Diabetes Genetics Replication and Meta-analysis (DIAGRAM) Consortium, Asian Genetic Epidemiology Network Type 2 Diabetes (AGEN-T2D) Consortium, South Asian Type 2 Diabetes (SAT2D) Consortium, Mexican American Type 2 Diabetes (MAT2D) Consortium, Type 2 Diabetes Genetic Exploration by Nex-generation sequencing in multi-Ethnic Samples (T2D-GENES) Consortium, Mahajan A, Go MJ, Zhang W, Below JE, Gault. 2014. Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility.. NATURE GENETICS 46 3: 234-244. 2014

Cousminer Diana L, Stergiakouli Evangelia, Berry Diane J, Ang Wei, Groen-Blokhuis Maria M, Körner Antje, Siitonen Niina, Ntalla Ioanna, Marinelli Marcella, Perry John RB, Kettunen Johannes, Jansen Rick, Surakka Ida, Timpson Nicholas J, Ring Susan, Mcmahon George, Power Chris, Wang Carol, Kähönen Mika, Jorma Viikari et. al.. 2014. Genome-wide association study of sexual maturation in males and females highlights a role for body mass and menarche loci in male puberty. HUMAN MOLECULAR GENETICS 23 16: 4451-64. 2014

Seppälä S, Laitinen T, Tarvainen MP, Tompuri T, Veijalainen A, Savonen K, Lakka T. 2013. Normal values for heart rate variability parameters in children 6-8 years of age: the PANIC Study. CLINICAL PHYSIOLOGY AND FUNCTIONAL IMAGING Article first published online: -. 2013

Wu Y, Waite LL, Jackson AU, Sheu WH, Buyske S, Absher D, Arnett DK, Boerwinkle E, Bonnycastle LL, Carty CL, Cheng I, Cochran B, Croteau-Chonka DC, Dumitrescu L, Eaton CB, Franceschini N, Guo X, Henderson BE, Hindorff LA, Kim E, et al. (including Stancakova A, Kuusisto J, Laakso M, Uusitupa M, Rauramaa R Lakka T.). 2013. Trans-Ethnic Fine-Mapping of Lipid Loci Identifies Population-Specific Signals and Allelic Heterogeneity That Increases the Trait Variance Explained. PLOS GENETICS [ONLINE) 9 3: e1003379. 2013

Willer CJ, Schmidt EM, Sengupta S, Peloso GM, Gustafsson S, Kanoni S, Ganna A, Chen J, Buchkovich ML, Mora S, Beckmann JS, Bragg-Gresham JL, Chang H-Y, Demirkan A, Den Hertog HM, Do R, Donnelly LA, Ehret GB, Esko T, Feitosa MF et.al.. 2013. Discovery and refinement of loci associated with lipid levels. NATURE GENETICS 45 11: 1274-1283. 2013

Veijalainen A, Tompuri T, Laitinen T, Lintu N, Viitasalo A, Laaksonen DE, Jääskeläinen J, Lakka TA. 2013. Metabolic risk factors are associated with stiffness index, reflection index and finger skin temperature in children. CIRCULATION JOURNAL 77 5: 1281-1288. 2013

Tompuri TT, Lakka TA, Hakulinen M, Lindi V, Laaksonen DE, Kilpeläinen TO, Jääskeläinen J, Lakka H-M, Laitinen T. 2013. Assessment of body composition by dual-energy X-ray absorptiometry, bioimpedance analysis and anthropometrics in children: the Physical Activity and Nutrition in Children study. CLINICAL PHYSIOLOGY AND FUNCTIONAL IMAGING 2015; 35 1: 21-33. 2013

Valtonen M, Heinonen Olli J, Lakka Timo A, Tammelin T. 2013. Lapsuusiän liikunnan merkitys - kardiometabolinen näkökulma. DUODECIM 129 11: 1153-8. 2013

Randall JC, Winkler TW, Kutalik Z, Berndt SI, Jackson AU, Monda KL, Kilpeläinen TO, Esko T, Mägi R, Li S, Workalemahu T, Feitosa MF, Croteau-Chonka DC, Day FR, Fall T, Ferreira T, Gustafsson S, Locke AE, Mathieson I, Scherag A, et al. (including J Kuusisto, M Laakso, M Atalay, T Lakka). 2013. Sex-stratified Genome-wide Association Studies Including 270,000 Individuals Show Sexual Dimorphism in Genetic Loci for Anthropometric Traits. PLOS GENETICS [ONLINE) 9 6: e1003500. 2013

Hu Y-J, Berndt SI, Gustafsson S, Ganna A, Genetic Investigation of ANthropometric Traits (GIANT) Consortium (including M Atalay, T Lakka, J Kuusisto, M Laakso), Hirschhorn J, North KE, Ingelsson E, Lin D-Y et.al.. 2013. Meta-analysis of gene-level associations for rare variants based on single-variant statistics. AMERICAN JOURNAL OF HUMAN GENETICS 93 2: 236-248. 2013

Berndt SI, Gustafsson S, Mägi R, Ganna A, Wheeler E, Feitosa MF, Justice AE, Monda KL, Croteau-Chonka DC, Day FR, Esko T, Fall T, Ferreira T, Gentilini D, Jackson AU, Luan J, Randall JC, Vedantam S, Willer CJ, Winkler TW, et al. (including Atalay M, Kuusisto J, Lakka TA, Stancakova A, Laakso M, Uusitupa M). 2013. Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture. NATURE GENETICS 45 5: 501-512. 2013

Haapala EA, Poikkeus A-M, Tompuri T, Kukkonen-Harjula K, Leppänen PHT, Lindi V, Lakka TA. 2013. Associations of motor and cardiovascular performance with academic skills in children. MEDICINE AND SCIENCE IN SPORTS AND EXERCISE online: x-x. 2013

Eloranta AM, Lindi V, Schwab U, Kiiskinen S, Venäläinen T, Lakka HM, Laaksonen DE, Lakka TA. 2013. Dietary factors associated with metabolic risk score in Finnish children aged 6-8 years: the PANIC study. EUROPEAN JOURNAL OF NUTRITION online [Epub ahead of print]: -. 2013

Do R, Willer CJ, Schmidt EM, Sengupta S, Gao C, Peloso GM, Gustafsson S, Kanoni S, Ganna A, Chen J, Buchkovich ML, Mora S, Beckmann JS, Bragg-Gresham JL, Chang H-Y, Demirkan A, Den Hertog HM, Donnelly LA, Ehret GB, Esko T et.al.. 2013. Common variants associated with plasma triglycerides and risk for coronary artery disease. NATURE GENETICS 45 11: 1345-52. 2013

Lintu N, Tompuri T, Viitasalo A, Soininen S, Laitinen T, Savonen K, Lindi V, Lakka TA. 2013. Cardiovascular fitness and haemodynamic responses to maximal cycle ergometer exercise test in children 6-8 years of age. Journal of Sports Sciences online [Epub ahead of print]: -. 2013

Manning AK, Hivert MF, Scott RA, Grimsby JL, Bouatia-Naji N, Chen H, Rybin D, Liu CT, Bielak LF, Prokopenko I, Amin N, Barnes D, Cadby G, Hottenga JJ, Ingelsson E, Jackson AU, Johnson T, Kanoni S, Ladenvall C, Lagou V et.al.. 2012. A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance NATURE GENETICS 44 6: 659-669. 2012

Viitasalo A, Laaksonen DE, Lindi V, Eloranta A-M, Jääskeläinen J, Tompuri T, Väisänen S, Lakka H-M, Lakka TA. 2012. Clustering of Metabolic Risk Factors Is Associated with High-Normal Levels of Liver Enzymes among 6- to 8-Year-Old Children: The PANIC Study. METABOLIC SYNDROME AND RELATED DISORDERS 10 5: 337-343. 2012

Valtonen MK, Laaksonen DE, Laukkanen JA, Tolmunen T, Viinamäki H, Lakka H-M, Lakka TA, Niskanen L, Kauhanen J. 2012. Low-grade inflammation and depressive symptoms as predictors of abdominal obesity. SCANDINAVIAN JOURNAL OF PUBLIC HEALTH 40 7: 674-680. 2012

Taal HR, St Pourcain B, Thiering E, Das S, Mook-Kanamori DO, Warrington NM, Kaakinen M, Kreiner-Moller E, Bradfield JP, Freathy RM, Geller F, Guxens M, Cousminer DL, Kerkhof M, Timpson NJ, Ikram MA, Beilin LJ, Bonnelykke K, Buxton JL, Charoen P et.al.. 2012. Common variants at 12q15 and 12q24 are associated with infant head circumference NATURE GENETICS 44 5: 532-538. 2012

Scott RA, Lagou V, Welch RP, Wheeler E, Montasser ME, Luan J, Mägi R, Strawbridge RJ, Rehnberg E, Gustafsson S, Kanoni S, Rasmussen-Torvik L, Yengo L, Lecoeur C, Shungin D, Sanna S, Sidore C, Johnson PCD, Jukema JW, Johnson T et.al.. 2012. Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways. NATURE GENETICS 44 9: 991-1005. 2012

Savonen KP, Kiviniemi V, Laaksonen DE, Lakka TA, Laukkanen JA, Tuomainen T-P, Rauramaa R. 2012. Two-minute heart rate recovery after cycle ergometer exercise and all-cause mortality in middle-aged men JOURNAL OF INTERNAL MEDICINE 270: 589-596. 2012

Morris AP, Voight BF, Teslovich TM, Ferreira T, Segrè AV, Steinthorsdottir V, Strawbridge RJ, Khan H, Grallert H, Mahajan A, Prokopenko I, Kang HM, Dina C, Esko T, Fraser RM, Kanoni S, Kumar A, Lagou V, Langenberg C, Luan J et.al.. 2012. Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes. NATURE GENETICS 44 9: 981-990. 2012

Vierola A, Suominen AL, Ikävalko T, Lintu N, Lindi V, Lakka H-M, Kellokoski J, Närhi M, Lakka TA. 2012. Clinical signs of temporomandibular disorders and various pain conditions among children 6 to 8 years of age: The Panic Study JOURNAL OF OROFACIAL PAIN 26 1: 17-25. 2012

Kouki R, Schwab U, Lakka TA, Hassinen M, Savonen K, Komulainen P, Krachler B, Rauramaa R. 2012. Diet, fitness and metabolic syndrome - The DR's EXTRA Study. NUTRITION, METABOLISM AND CARDIOVASCULAR DISEASES 22: 553-560. 2012

Ikävalko T, Tuomilehto H, Pahkala R, Tompuri T, Laitinen T, Myllykangas R, Vierola A, Lindi V, Närhi M, Lakka TA. 2012. Craniofacial morphology but not excess body fat is associated with risk of having sleep-disordered breathing -The PANIC Study (a questionnaire-based inquiry in 6-8-year-olds). EUROPEAN JOURNAL OF PEDIATRICS 171 12: 1747-1752. 2012

Ikram MA, Fornage M, Smith AV, Seshadri S, Schmidt R, Debette S, Vrooman HA, Sigurdsson S, Ropele S, Taal HR, Kanamori-Mook DO, Coker LH, Longstreth Jr WT, Niessen WJ, DeStefano AL, Beiser A, Zijdenbos AP, Struchalin M, Jack Jr CR, Rivadeneira F et.al.. 2012. Common variants at 6q22 and 17q21 are associated with intracranial volume NATURE GENETICS 44 5: 539-544. 2012

Horikoshi M, Yaghootkar H, Mook-Kanamori DO, Sovio U, Taal HR, Hennig BJ, Bradfield JP, St Pourcain B, Evans DM, Charoen P, Kaakinen M, Cousminer DL, Lehtimäki T, Kreiner-Møller E, Warrington NM, Bustamante M, Feenstra B, Berry DJ, Thiering E et.al.. 2012. New loci associated with birth weight identify genetic links between intrauterine growth and adult height and metabolism. NATURE GENETICS - -: 1-10. 2012

Eloranta A-M, Lindi V, Schwab U, Tompuri T, Kiiskinen S, Lakka H-M, Laitinen T, Lakka TA. 2012. Dietary factors associated with overweight and body adiposity in Finnish children aged 6-8 years: the PANIC study. INTERNATIONAL JOURNAL OF OBESITY 36: 950-955. 2012

Bradfield JP, Taal HR, Timpson NJ, Scherag A, Lecoeur C, Warrington NM, Hypponen E, Holst C, Valcarcel B, Thiering E, Salem RM, Schumacher FR, Cousminer DL, Sleiman PMA, Zhao J, Berkowitz RI, Vimaleswaran KS, Jarick I, Pennell CE, Evans DM et.al.. 2012. A genome-wide association meta-analysis identifies new childhood obesity loci NATURE GENETICS 44 5: 526-531. 2012

Ahola AJ, Harjutsalo V, Saraheimo M, Forsblom C, Groop PH; FinnDiane Study Group.. 2012. Purchase of antidepressant agents by patients with type 1 diabetes is associated with increased mortality rates in women but not in men. DIABETOLOGIA 55 1: 73-79. 2012

Juhakoski R, Malmivaara A, Lakka TA, Tenhonen S, Hannila M-L, Arokoski JPA. 2012. Determinants of pain and functioning in hip osteoarthritis - a two-year prospective study. CLINICAL REHABILITATION online: -. 2012

Lintu N, Himanen A, Karjalainen P, Elonranta A-M, Tompuri T, Viitasalo A, Laitinen T, Tuomilehto H, Lakka H-M, Lindi V, Lakka T. 2011. Physical activity, body composition and sleep in children: Hakkarainen Anni, Liukkonen Jarmo, Linnamo Vesa, International congress on enhancement of physical activity of children and youth 2011. 45. 2011

Veijalainen A, Tompuri T, Lakka H-M, Laitinen T, & Lakka TA. 2011. Reproducibility of pulse contour analysis in children before and after maximal exercise stress test: The physical activity and nutrition in children (PANIC) study. CLINICAL PHYSIOLOGY AND FUNCTIONAL IMAGING 31: 132-138. 2011

Savonen K, Krachler B, Hassinen M, Komulainen P, Kiviniemi V, Lakka TA and Rauramaa R. 2011. The current standard measure of cardiorespiratory fitness introduces confounding by body mass: the DR's EXTRA study. INTERNATIONAL JOURNAL OF OBESITY 36 8: 1135-1140. 2011

Sanna S, Li B, Mulas A, Sidore C, Kang HM, Jackson AU, Grazia Piras M, Usala G, Maninchedda G, Sassu A, Serra F, Palmas MA, Wood III WH, Njølstad I, Laakso M, Hveem K, Tuomilehto J, Lakka TA, Rauramaa R, Boehnke M,et al.. 2011. Fine mapping of five loci associated with low-density lipoprotein cholesterol detects variants that double the explained heritability PLOS GENETICS [ONLINE) 7: e1002198. 2011

Kouki R, Schwab U, Hassinen M, Komulainen P, Heikkilä H, Lakka TA, Rauramaa R.. 2011. Food consumption, nutrient intake and the risk of having metabolic syndrome: the DR's EXTRA Study.. EUROPEAN JOURNAL OF CLINICAL NUTRITION 65: 368-377. 2011

Kilpeläinen Tuomas O, Qi Lu, Brage Soren, Sharp Stephen J., Sonestedt Emily, Demerath Ellen, Ahmad Tariq, Mora Samia, Kaakinen Marika, Sandholt Camilla H, Holzapfel Christina, Autenrieth Christine S., Hyppönen Elina, Cauchi Stéphane , He Meian, Kutalik Zoltan, Kumari Meena, Stancaková Alena, Meidtner Karina, Balkau Beverley et al.. 2011. Physical activity attenuates the influence of FTO variants on obesity risk: A meta-analysis of 218,166 adults and 19,268 children PLOS MEDICINE 8 11: e1001116. 2011

Kesäniemi A , Kettunen J, Ketola E, Kujala U, Kukkonen-Harjula K, Lakka T, Rauramaa R, Rauramo I, Tikkanen H, Vuori I. 2011. Liikunta. Käypä hoito -suositus DUODECIM 127 2: 150-151. 2011

Hakola L, Komulainen P, Hassinen M, Savonen K, Litmanen H, Lakka TA, Rauramaa R. 2011. Cardiorespiratory fitness in aging men and women: the DR's EXTRA study SCANDINAVIAN JOURNAL OF MEDICINE & SCIENCE IN SPORTS 21: 679-687. 2011

Eloranta AM, Lindi V, Schwab U, Kiiskinen S, Kalinkin M, Lakka HM, Lakka TA. 2011. Dietary factors and their associations with socioeconomic background in Finnish girls and boys 6-8 years of age: the PANIC Study EUROPEAN JOURNAL OF CLINICAL NUTRITION 65 11: 1211-8. 2011

Baldassarre D, Nyyssönen K, Rauramaa R, de Faire U, Hamsten A, Smit AJ, Mannarino E, Humphries SE, Giral P, Grossi E, Veglia F, Paoletti R, Tremoli E; IMPROVE study group.. 2010. Cross-sectional analysis of baseline data to identify the major determinants of carotid intima-media thickness in a European population: the IMPROVE study. EUROPEAN HEART JOURNAL 614-22 5: 614-622. 2010

Eloranta A-m, Lindi V, Schwab U, Kiiskinen S, Kalinkin M, Lintu N, Karjalainen P, Himanen A, Karjalainen J, Tompuri T, Viitasalo A, Lakka H-M, Lakka T & Lasten liikunta ja ravitsemus -tutkimus, Itä-Suomen yliopisto. 2010. Lasten liikunta ja ravitsemus -tutkimus selvittää alakoululaisten elintapoja. BOLUS : RAVITSEMUSTERAPEUTTIEN YHDISTYKSEN LEHTI 4: 30-33. 2010

Hassinen M, Lakka TA, Hakola L, Savonen K, Komulainen P, Litmanen H, Kiviniemi V, Kouki R, Heikkilä H, & Rauramaa R. 2010. Cardiorespiratory fitness and metabolic syndrome in older men and women. DIABETES CARE 33 7: 1655-1657. 2010

Ilanne-Parikka P, Laaksonen DE, Eriksson JG, Lakka TA, Lindström J, Peltonen M, Aunola S, Keinänen-Kiukaanniemi S, Uusitupa M & Tuomilehto J. On behalf of the Finnish diabetes prevention study group. 2010. Leisure-time physical activity and the metabolic syndrome in the Finnish diabetes prevention study. DIABETES CARE 33 7: 1610-1617. 2010

Kesäniemi A, Kettunen J, Ketola E, Kujala U, Kukkonen-Harjula K, Lakka T, Rauramaa R, Rauramo I, Tikkanen H & Vuori I. 2010. Aikuisten liikunta. DUODECIM 126: 150-1. 2010

Komulainen P, Kivipelto M, Lakka TA, Savonen K, Hassinen M, Kiviniemi V, Hänninen T & Rauramaa R. 2010. Exercise, fitness and cognition - A randomised controlled trial in older indivuals: The DR's EXTRA study. European Geriatric Medicine 1: 266-272. 2010

Valtonen M, Laaksonen DE, Laukkanen J, Tolmunen T, Rauramaa R, Viinamäki H, Mursu J, Savonen K, Lakka TA, Niskanen L & Kauhanen J. 2010. Sedentary lifestyle and emergence of hopelessness in middle-aged men. EUROPEAN JOURNAL OF CARDIOVASCULAR PREVENTION AND REHABILITATION 17 5: 524-9. 2010

Veijalainen A, Tompuri T, Lakka HM, Laitinen T & Lakka TA. 2010. Reproducibility of pulse contour analysis in children before and after maximal exercise stress test: The Physical Activity and Nutrition in Children (PANIC) Study. CLINICAL PHYSIOLOGY AND FUNCTIONAL IMAGING online 2010 Nov 5: 1-7. 2010

Komulainen P, Savonen K, Litmanen H, Lakka TA, Kiviniemi V, Hassinen M, Kivipelto M, Hänninen T, Heikkilä H, Kouki R, Hakola L, Rauramaa R. 2009. Kardiorespiratorinen suorituskyky muistin ennustajana ikääntyneillä miehillä ja naisilla. LIIKUNTA JA TIEDE 46 5: 41. 2009

Valtonen M, Laaksonen DE, Laukkanen J, Tolmunen T, Rauramaa R, Viinamäki H, Kauhanen J, Lakka T, Niskanen L. 2009. Leisure-time physical activity, cardiorespiratory fitness and feelings of hopelessness in men. BMC PUBLIC HEALTH 9 204. 2009

Laukkanen JA, Laaksonen D, Lakka TA, Savonen K, Rauramaa R, Mäkikallio T, Kurl S. 2009. Determinants of cardiorespiratory fitness in men aged 42 to 60 years with and without cardiovascular disease. AMERICAN JOURNAL OF CARDIOLOGY 103: 1598-1604. 2009

Hassinen M, Savonen K, Lakka TA, Komulainen P, Litmanen H, Kiviniemi V, Kouki R, Heikkilä H, Hakola L, Rauramaa R. 2009. Kardiorespiratorinen suorituskyky ja metabolinen oireyhtymä. LIIKUNTA JA TIEDE 46 5: 34-35. 2009

Kiiskinen S, Schwab U, Kalinkin M, Lindi V, Tompuri T, Lakka H-M, Lakka T. 2009. Lasten ruokavaliossa on huolestuttavia piirteitä. SUOMEN LÄÄKÄRILEHTI 64: 144-145. 2009

Hu G, Lakka TA, Barengo NC, Tuomilehto J. 2009. Exercise and type 2 diabetes prevention. Teoksessa: Lignalli AT (toim.), Handbook of Type 2 Diabetes in the Middle Aged and Elderly [E-Book].Nova Science Publisher. ss. 93-111. 2009

Hu G, Lakka TA, Tuomilehto J. 2009. Physical activity, fitness, and the preventioon of type 2 diabetes. Teoksessa: Lee I-M (toim.), Epidemiologic Methods in Physical Avtivity Studies.Oxford University Press. ss. 201-224. 2009

Savonen KP, Kiviniemi V, Laukkanen JA, Lakka TA, Rauramaa TH, Salonen JT, Rauramaa R. 2008. Chronotropic incompetence and mortality in middle-aged men with known or suspected coronary heart disease. EUROPEAN HEART JOURNAL 29 15: 1896-1902. 2008

Wadén J, Forsblom C, Thorn LM, Saraheimo M, Rosengård-Bärlund M, Heikkilä O, Lakka TA, Tikkanen H, Groop PH, FinnDiane Study Group, Karhapää P, Laakso M, Moilanen L, Niskanen L, Vauhkonen I, Voutilainen E. 2008. Physical activity and diabetes complications in patients with type 1 diabetes. The Finnish Diabetic Nephropathy (FinnDiane) Study. DIABETES CARE 31: 230-232. 2008

Savonen KP, Lakka TA, Laukkanen JA, Rauramaa TH, Salonen JT, Rauramaa R. 2008. Workload at the heart rate of 100 beats/min and mortality in middle-aged men known or suspected coronary heart disease. Heart 94: E14. 2008

Savonen KP, Lakka TA, Laukkanen JA, Rauramaa TH, Salonen JT, Rauramaa R. 2008. Usefulness of chronotropic incompetence in response to exercise as a predictor of myocardial infarction in middle-aged men without cardiovascular disease. AMERICAN JOURNAL OF CARDIOLOGY 101: 992-998. 2008

Laaksonen DE, Niskanen L, Nyyssönen K, Lakka TA, Laukkanen JA, Salonen JT. 2008. Dyslipidaemia as a predictor of hypertension in middle-aged men EUROPEAN HEART JOURNAL 29: 2561-2568. 2008

Komulainen P, Pedersen M, Hänninen T, Bruunsgaard H, Lakka TA, Kivipelto M, Hassinen M, Rauramaa TH, Pedersen BK, Rauramaa R. 2008. BDNF is a novel marker of cognitive function in ageing women: the DR's EXTRA Study. NEUROBIOLOGY OF LEARNING AND MEMORY 90 4: 596-603. 2008

Kilpeläinen TO, Lakka TA, Laaksonen DE, Lindström J, Eriksson JG, Valle TT, Hämäläinen H, Ilanne-Parikka P, Keinänen-Kiukaanniemi S, Lindi V, Tuomilehto J, Uusitupa M, Laakso M. 2008. SNPs in PPARG associte with type 2 diabetes and intract with physival activity. MEDICINE AND SCIENCE IN SPORTS AND EXERCISE 40: 25-33. 2008

Kilpeläinen TO, Lakka TA, Laakosnen DE, Mager U, Salopuro T, Kubaszek A, Todorova B, Laukkanen O, Lindström J, Eriksson JG, Hämäläinen H, Aunola S, Ilanne-Parikka P, Keinänen-Kiukaanniemi S, Tuomilehto J, Laakso M, Uusitupa M. 2008. Interaction of single nucleotide polymorphisms in ADRB2, ADRB3, TNF, IL6, IGF1R, LIPC, LEPR, and GHRL with physical activity on the risk of type 2 diabetes mellitus and changes in characteristics of the metabolic syndrome. The Finnish Diabetes Prevention Study. METABOLISM: CLINICAL AND EXPERIMENTAL 57: 428-436. 2008

Hu G, Lakka TA, Tuomilehto J. 2008. Physical activity, fitness, and prevention of type 2 diabetes: Lee IM, Epidemiologic Methods in Physical Activity Studies.Oxford University Press. 201-224. 2008

Hassinen M, Lakka TA, Savonen K, Litmanen H, Kiviaho L, Laaksonen DE, Komulainen P, Rauramaa R. 2008. Cardiorespiratory fitness as a feature of metabolic syndrome in older men and women. DIABETES CARE 31 6: 1242-1247. 2008

Borodulin K, Laatikainen T, Lahti-Koski M, Jousilahti P, Lakka TA. 2008. Association of age and education with different types of leisure-time physical activity among 4437 Finnish adults. JOURNAL OF PHYSICAL ACTIVITY AND HEALTH 5 2: 242-251. 2008

Komulainen P, Lakka TA, Kivipelto M, Hassinen M, Helkala E-L, Haapala I, Nissinen A, Rauramaa R. 2007. Metabolic syndrome and cognitive function: a population-based follow-up study in elderly women DEMENTIA AND GERIATRIC COGNITIVE DISORDERS 23: 29-34. 2007

Wadén J, Thorn LM, Forsblom C, Lakka T, Saraheimo M, Rosengård-Bärlund M, Heikkilä O, Wessman M, Turunen JA, Parkkonen M, Tikkanen H, Groop P-H, on behalf of the FinnDiane Study Group. 2007. Leisure-time physical activity is associated with the metaboic syndrome in type 1 diabetes: Effect of the PPAR-gamma Pro12Ala polymorphism: the FinnDiane Study. DIABETES CARE 30: 1618-1620. 2007

Savonen KP, Lakka TA, Laukkanen JA, Rauramaa TH, Salonen JT, Rauramaa R. 2007. Effectiveness of workload at the heart rate of 100 beats/min in predicting cardiovascular mortality in men aged 42, 48, 54, or 60 years at baseline. AMERICAN JOURNAL OF CARDIOLOGY 100: 563-568. 2007

Lakka TA, Laaksonen DE. 2007. Physical activity in prevention and treatment of the metabolic syndrome. APPLIED PHYSIOLOGY, NUTRITION AND METABOLISM 32: 76-88. 2007

Komulainen P, Lakka TA, Kivipelto M, Hassinen M, Penttilä IM, Helkala E-L, Gylling H, Nissinen A, Rauramaa R. 2007. Serum high sensitivity C-reactive protein and cognitive function in elderly women AGE AND AGEING 36: 443-448. 2007

Hu G, Jousilahti P, Borodulin K, Barengo NC, Lakka TA, Nissinen A, Tuomilehto J. 2007. Occupational, commuting and leisure-time physical activity in relation to coronary heart disease among middle-aged Finnish men and women. ATHEROSCLEROSIS 194: 490-497. 2007

Komulainen P, Kivipelto M, Lakka TA, Hassinen M, Helkala E-L, Patja K, Nissinen A, Rauramaa R. 2007. Carotid intima-media thickness and cognitive function in elderly women: a population-based study. NEUROEPIDEMIOLOGY 28: 207-213. 2007

Kilpeläinen TO, Lakka TA, Laaksonen DE, Laukkanen O, Lindström J, Eriksson JG, Valle TT, Hämäläinen H, Aunola S, Ilanne-Parikka P, Keinänen-Kiukaanniemi S, Tuomilehto J, Uusitupa M, Laakso M, for the Finnish Diabetes Prevention Study Group, Laakso M. 2007. Physical activity modifies the effect of SNPs in the SLC2A2 (GLUT2) and ABCC8 (SUR1) genes on the risk of developing type 2 diabetes. PHYSIOLOGICAL GENOMICS (PRINTED AND ONLINE) 31: 264-272. 2007

Hu G, Lakka TA, Lakka H-M, Tuomilehto J, Lakka TA. 2007. Obesity, physical activity, and nutrition in the metabolic syndrome. Teoksessa: Krentz AJ, Wong ND (toim.), Metabolic Syndrome and Cardiovascular Disease.Informa Healthcare. ss. 241-278. 2007

Hu G, Lakka TA, Kilpeläinen T, Tuomilehto J. 2007. Epidemiological studies of exercise in diabetes prevention. APPLIED PHYSIOLOGY, NUTRITION AND METABOLISM 32: 583-595. 2007

Hassinen M, Lakka TA, Komulainen P, Haapala I, Nissinen A, Rauramaa R. 2007. Association of waist and hip circumference with 12-year progression of carotid intima-media thickness in elderly women. INTERNATIONAL JOURNAL OF OBESITY 31: 1406-1411. 2007

Lakka H-M, Lakka TA, Rankinen T, Rice T, Rao DC, Leon AS, Skinner JS, Bouchard C. 2006. The TNF-a G-308A polymorphism is associated with C-reactive protein levels: The HERITAGE Family Study VASCULAR PHARMACOLOGY 44: 377-383. 2006

Virtanen JK, Voutilainen S, Rissanen TH, Happonen P, Mursu J, Laukkanen JA, Poulsen H, Lakka TA, Salonen JT. 2006. High dietary methionine intake increases the risk of acute coronary events in middle-aged men. NUTRITION, METABOLISM AND CARDIOVASCULAR DISEASES 16: 113-120. 2006

Laukkanen JA, Kurl S, Salonen JT, Lakka TA, Rauramaa R. 2006. Peak oxygen pulse during exercise as a predictor for coronary heart disease and all cause death. HEART 92 9: 1219-1224. 2006

Lakka TA, Rankinen T, Rice T, Leon AS, Rao DC, Skinner JS, Bouchard C. 2006. Quantitative trait locus on chromosme 20q13 for plasma levels of C-reactive protein in healthy whites: the HERITAGE family sudy. PHYSIOLOGICAL GENOMICS (PRINTED AND ONLINE) 27: 103-107. 2006

Lakka TA, Lakka H-M, Rankinen T, Bouchard C. 2006. Letter to the editor (Exercise and inflammation; reply). EUROPEAN HEART JOURNAL 27 11: 1385-1386. 2006

Savonen KP, Lakka TA, Laukkanen JA, Halonen PM, Rauramaa TH, Salonen JT, Rauramaa R. 2006. Heart rate response during exercise test and cardiovascular mortality in middle-aged men. EUROPEAN HEART JOURNAL 27: 582-588. 2006

Hu G, Rico-Sanz J, Lakka TA, Tuomilehto J. 2006. Exercise, genetics and prevention of type 2 diabetes. ESSAYS IN BIOCHEMISTRY 42: 177-192. 2006

Hu G, Lakka TA, Lakka H-M, Tuomilehto J. 2006. Lifestyle management in the metabolic syndrome. METABOLIC SYNDROME AND RELATED DISORDERS 4: 270-286. 2006

Herder C, Peltonen M, Koenig W, Kräft I, Mûller-Scholze S, Martin S, Lakka T, Ilanne-Parikka P, Eriksson JG, Hämäläinen H, Keinänen-Kiukaanniemi S, Valle TT, Uusitupa M, Lindström J, Kolb H, Tuomilehto J. 2006. Systemic immune mediators and lifestyle changes in the prevention of type 2 diabetes. Results from the Finnish diabes prevention study. DIABETES (NY) 55: 2340-2346. 2006

Hassinen M, Lakka TA, Komulainen P, Gylling H, Nissinen A, Rauramaa R. 2006. C-reactive protein and metabolic syndrome in elderly women. A 12-year follow-up study DIABETES CARE 29: 931-932. 2006

Hassinen M, Komulainen P, Lakka TA, Väisänen SB, Haapala I, Gylling H, Alen M, Schmidt-Trucksäss A, Nissinen A, Rauramaa R. 2006. Metabolic syndrome and the progression of carotid intima-media thickness in elderly women. ARCHIVES OF INTERNAL MEDICINE 166: 444-449. 2006

Borodulin K, Tuomilehto J, Peltonen M, Lakka TA, Sundvall J, Jousilahti P. 2006. Association of leisure time physical activity abdomimal obesity with fsting serum insulin and 2-h postchallenge plasma glucose levels. DIABETIC MEDICINE 23: 1025-1028. 2006

Barengo NC, Kastarinen M, Lakka T, Nissinen A, Tuomilehto J. 2006. Different forms of physical activity and cardiovascular risk factors among 24-64-year-old men and women in Finland. EUROPEAN JOURNAL OF CARDIOVASCULAR PREVENTION AND REHABILITATION 13: 51-59. 2006

Ukkola O, Rankinen T, Lakka T, Leon AS, Skinner JS, Wilmore JH, Rao DC, Kesäniemi YA, Bouchard C. 2005. Protein tyrosine phosphatase 1B variant associated with fat distribution and insulin metabolism OBESITY (SILVER SPRING, MD.) 13 5: 829-834. 2005

Lakka TA, Lakka H-M, Rankinen T, Leon AS, Rao DC, Skinner JS, Wilmore JH, Bouchard C. 2005. Effect of exercise training on plasma levels of C-reactive protein in healthy adults: the HERITAGE family study. EUROPEAN HEART JOURNAL 26: 2018-2025. 2005

Laaksonen DE, Lindström J, Lakka TA, Eriksson JG, Niskanen L, Wikström K, Aunola S, Keinänen-Kiukaanniemi S, Laakso M, Valle TT, Ilanne-Parikka P, Louheranta A, Hakumäki M, Kaikkonen H, Härkönen P, Sundvall J, Tuomilehto J, Uusitupa M, Louheranta A. 2005. Physical activity in the prevention of type 2 diabetes. The Finnish diabetes prevention study. DIABETES (NY) 54: 158-165. 2005

Hassinen M, Komulainen P, Lakka TA, Väisänen SB, Rauramaa R. 2005. Associations of body composition and physical activity with balance and walking ability in the elderly. JOURNAL OF PHYSICAL ACTIVITY AND HEALTH 3: 298-306. 2005

Hu G, Jousilahti P, Barengo NC, Qiao Q, Lakka TA, Tuomilehto J. 2005. Physical activity, cardiovascular risk factors, and mortality among Finnish adults with diabetes. DIABETES CARE 28 4: 799-805. 2005

Boulé NG, Weisnagel SJ, Lakka TA, Tremblay A, Bergman RN, Rankinen T, Leon AS, Skinner JS, Wilmore JH, Rao DC, Bouchard C. 2005. Effects of exercise training on glucose homeostasis. The Heritage family studies. DIABETES CARE 28 1: 108-114. 2005

Borodulin K, Laatikainen T, Lahti-Koski M, Lakka TA, Laukkanen R, Sarna S, Jousilahti P. 2005. Associations between estimated aerobic fitness and cardiovascular risk factors in adults with different levels of abdominal obesity. EUROPEAN JOURNAL OF CARDIOVASCULAR PREVENTION AND REHABILITATION 12 1: 126-131. 2005

Barengo NC, Hu G, Kastarinen M, Lakka TA, Pekkarinen H, Nissinen A, Tuomilehto J. 2005. Low physical activity as a predictor for antihypertensive drug treatment in 25- 64-year-old populations in Eastern and south-western Finland. JOURNAL OF HYPERTENSION 23: 293-299. 2005

Barengo NC, Hu G, Lakka TA, Pekkarinen H, Nissinen A, Tuomilehto J. 2004. Low physical activity as a predictor for total and cardiovascular disease mortality in middle-aged men and women in Finland. EUROPEAN HEART JOURNAL 25: 2204-2211. 2004

Hu G, Barengo NC, Tuomilehto J, Lakka TA, Nissinen A, Jousilahti P. 2004. Relationship of physical activity and body mass index to the risk of hypertension: a prospective study in Finland. HYPERTENSION 43: 25-30. 2004

Hu G, Lakka TA, Barengo NC, Tuomilehto J. 2004. Physical activity in the prevention of type 2 diabetes. KARDIOVASKULÄRE MEDIZIN 7 11: 394-405. 2004

Laaksonen DE, Niskanen L, Lakka H-M, Lakka TA, Uusitupa M, Laaksonen DE. 2004. Epidemiology and treatment of the metabolic syndrome. Annals of Medicine 36: 332-346. 2004

Laukkanen JA, Kurl S, Salonen R, Lakka TA, Rauramaa R, Salonen JT. 2004. Systolic blood pressure during recovery from exercise and the risk of acute myocardial infarction in middle-aged men. HYPERTENSION 44: 820-825. 2004

Lakka TA, Laaksonen DE, Lakka H-M, Männikkö N, Niskanen LK, Rauramaa R, Salonen JT. 2003. Sedentary lifestyle, poor cardiorespiratory fitness, and the metabolic syndrome. MEDICINE AND SCIENCE IN SPORTS AND EXERCISE 35 8: 1279-1286. 2003

Laaksonen DE, Lakka H-M, Lynch J, Lakka TA, Niskanen L, Rauramaa R, Salonen JT, Kauhanen J. 2003. Cardiorespiratory fitness and vigorous leisure-time physical activity modify the association of small size at birth with the metabolic syndrome. DIABETES CARE 26 7: 2156-2164. 2003

Lakka TA, Lakka H-M, Salonen R, Kaplan GA, Salonen JT. 2001. Abdominal obesity is associated with accelerated progression of carotid atherosclerosis in men. ATHEROSCLEROSIS 154: 497-504. 2001

Laukkanen JA, Lakka TA, Rauramaa R, Kuhanen R, Venäläinen JM, Salonen R, Salonen JT. 2001. Cardiovascular fitness as a predictor of mortality in men. ARCHIVES OF INTERNAL MEDICINE 161: 825-831. 2001

Puntila E, Kröger H, Lakka T, Tuppurainen M, Jurvelin J, Honkanen R. 2001. Leisure-time physical activity and rate of bone loss among peri- and postmenopausal women: a longitudinal study. BONE 29 5: 442-446. 2001

Rauramaa R, Lakka TA. 2001. Liikuntaa sepelvaltimotaudin ehkäisyyn ja hoitoon DUODECIM 117: 633-638. 2001

Valkonen V-P, Päivä H, Salonen JT, Lakka TA, Lehtimäki T, Laakso J, Laaksonen R. 2001. Risk of acute coronary events and serum concentration of asymmetrical dimethylarginine LANCET 358: 2127-2128. 2001

Voutilainen S, Rissanen TH, Virtanen J, Lakka TA, Salonen JT. 2001. Low dietary folate intake is associated with an excess incidence of acute coronary events. The Kuopio Ischemic Heart Disease Risk Factor Study. CIRCULATION 103: 2674-2680. 2001

Voutilainen S, Lakka TA, Porkkala-Sarataho E, Rissanen T, Kaplan GA, Salonen JT. 2000. Low serum folate concentrations are associated with an excess incidence of acute coronary events: the Kuopio Ischaemic Heart Disease Risk Factor Study. EUROPEAN JOURNAL OF CLINICAL NUTRITION 54: 424-428. 2000

Vanharanta M, Voutilainen S, Lakka TA, van der Lee M, Adlercreutz H, Salonen JT. 1999. Risk of acute coronary events according to serum concentrations of enterolactone: a prospective population-based case-control study. LANCET 354: 2112-2115. 1999

Salonen JT, Lakka TA, Lakka H-M, Valkonen V-P, Everson SA, Kaplan GA. 1998. Hyperinsulinemia is associated with the incidence of hypertension and dyslipidemia in middle-aged men. DIABETES (NY) 47: 270-275. 1998

Everson SA, Goldberg DE, Helmrich SP, Lakka TA, Lynch JW, Kaplan GA, Salonen JT. 1998. Weight gain and the risk of developing insulin resistance syndrome. DIABETES CARE 21: 1637-1643. 1998

Kauhanen J, Kaplan GA, Goldberg DD, Cohen RD, Lakka TA, Salonen JT. 1997. Frequent hangovers and cardiovascular mortality in middle-aged men EPIDEMIOLOGY 8: 310-314. 1997

Lakka TA, Salonen JT. 1997. The physical activity questionnaires of the Kuopio Ischemic Heart Disease Risk Factor Study (KIHD) MEDICINE AND SCIENCE IN SPORTS AND EXERCISE. SUPPLEMENT 29 6: S46-S58. 1997

Puntila E, Kröger H, Lakka T, Honkanen R, Tuppurainen M. 1997. Physical activity in adolescence and bone density in peri- and postmenopausal women: A population-based study BONE 21: 363-367. 1997

Tuomainen T-P, Nyyssönen K, Salonen R, Tervahauta A, Korpela H, Lakka T, Kaplan GA, Salonen JT. 1997. Body iron stores are associated with serum insulin and blood glucose concentrations. DIABETES CARE 20 3: 426-428. 1997

Lakka TA, Kauhanen J, Salonen JT. 1996. Conditioning leisure time physical activity and cardiorespiratory fitness in sociodemographic groups of middle-aged men in Eastern Finland. INTERNATIONAL JOURNAL OF EPIDEMIOLOGY 25 1: 86-93. 1996

Lakka TA, Lakka H-M, Salonen JT. 1996. Hyperinsulinemia and the risk of coronary heart disease. NEW ENGLAND JOURNAL OF MEDICINE 335 13: 976-977. 1996

Lynch J, Helmrich SP, Lakka TA, Kaplan GA, Cohen RD, Salonen R, Salonen JT. 1996. Moderately intense physical activities and high levels of cardiorespiratory fitness reduce the risk of non-insulin-dependent diabetes mellitus in middle-aged men. ARCHIVES OF INTERNAL MEDICINE 156: 1307-1314. 1996

Räsänen J, Kauhanen J, Lakka TA, Kaplan GA, Salonen JT. 1996. Religious affiliation and all-cause mortality: a prospective population study in middle-aged men in Eastern Finland. INTERNATIONAL JOURNAL OF EPIDEMIOLOGY 25 6: 1244-1249. 1996

Lakka TA, Nyyssönen K, Salonen JT. 1994. Higher levels of conditioning leisure time physical activity are associated with reduced levels of stored iron in Finnish men. AMERICAN JOURNAL OF EPIDEMIOLOGY 140: 148-160. 1994

Lakka TA, Venäläinen JM, Rauramaa R, Salonen R, Tuomilehto J, Salonen JT. 1994. Relation of leisure-time physical activity and cardiorespiratory fitness to the risk of acute myocardial infarction in men. NEW ENGLAND JOURNAL OF MEDICINE 330: 1549-1554. 1994

Yhteystiedot

Organisaatio

Sähköposti

Puhelin

Tutkimusryhmät ja -projektit

Tutkimusryhmät - UEF

PROJEKTIT - UEF

Linkit

Julkaisut

Tiedostot