Tuomas Karhu

Tarkenna hakuasi

Tiedot Julkaisut

Tutkijatohtori, jonka tutkimus kohdistuu unisairauksien diagnostiikan kehitykseen hyödyntäen kehittynyttä biosignaalien käsittelyä.
Väitöskirjani aiheeni oli ”Nocturnal hypoxic load in the evaluation of the progression of sleep apnea”.

Tutkimusryhmät

Sleep Technology and Analytics Research (STAR) Group 01.01.2017 -

Avainsanat

diagnostiikka fysiikka hypoxia lääketieteellinen fysiikka signaalianalyysi signaalinkäsittely uniapnea

Julkaisut

25/25 kappaletta

Differential associations of arousals and respiratory events on oxygen desaturation and resaturation parameters in sleep
Howarth, Timothy P; Karhu, Tuomas; Saad, Helmi Ben; Bahammam, Ahmed; Luukinen, Mieli; Pahari, Purbanka; Ebrahimian, Serajeddin, 2026, Sleep and breathing, 30, 5, 257. A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä
Five-year longitudinal changes in oxygen saturation parameters in Obstructive Sleep Apnoea: Impact of age, body mass index, and comorbidities
Howarth, Timothy P; Karhu, Tuomas; Leppänen, Timo; Saad, Helmi Ben; Bahammam, Ahmed; Nikkonen, Sami, 2026, Sleep medicine, 143, 108866. A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä
RAVEN: Software for automated sleep microstructure analysis from electroencephalography
Arolaakso, Mikko; Pitkänen, Henna; Pitkänen, Minna; Rusanen, Matias; Korkalainen, Henri; Karhu, Tuomas; Häkkinen, Saila; Hiltunen, Mika; Kainulainen, Samu, 2026, Biomedical signal processing and control, 123, Part B, 110552. A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä
Nocturnal short-term HRV reflects impaired daytime vigilance better than overnight HRV in suspected OSA patients
Hietakoste, Salla; Karhu, Tuomas; Lombardi, Carolina; Armañac-Julián, Pablo; Bailón, Raquel; Duce, Brett; Sillanmäki, Saara; Töyräs, Juha; Leppänen, Timo; Myllymaa, Sami; Kainulainen, Samu, 2025, Sleep, 48, 4, zsae282. A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä
Optimal Electroencephalogram and Electrooculogram Signal Combination for Deep Learning-based Sleep Staging
Tashakori, Masoumeh; Rusanen, Matias; Karhu, Tuomas; Huttunen, Riku; Leppanen, Timo; Nikkonen, Sami, 2025, IEEE journal of biomedical and health informatics, 29, 7, 4741-4747. A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä
The interaction between comorbidities and sleep stages influences oxygen re‐saturation characteristics
Howarth, Timothy P; Hietakoste, Salla; Ebrahimian, Serajeddin; Rissanen, Marika; Kainulainen, Samu; Karhu, Tuomas, 2025, Journal of sleep research, 34, 6, e14459. A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä
A comparative analysis of unsupervised machine‐learning methods in PSG‐related phenotyping
Ghorvei, Mohammadreza; Karhu, Tuomas; Hietakoste, Salla; Ferreira‐Santos, Daniela; Hrubos‐Strøm, Harald; Islind, Anna Sigridur; Biedebach, Luka; Nikkonen, Sami; Leppänen, Timo; Rusanen, Matias, 2024, Journal of sleep research, 34, 3, e14349. A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä
Excessive daytime sleepiness is associated with relative delta frequency power among patients with mild OSA
Howarth, Timothy; Tashakori, Masoumeh; Karhu, Tuomas; Rusanen, Matias; Pitkänen, Henna; Oksenberg, Arie; Nikkonen, Sami, 2024, Frontiers in neurology, 15, 1367860. A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä
Interhemispheric differences of electroencephalography signal characteristics in different sleep stages
Tashakori, Masoumeh; Rusanen, Matias; Karhu, Tuomas; Grote, Ludger; Nath, Rajdeep Kumar; Leppänen, Timo; Nikkonen, Sami, 2024, Sleep medicine, 117, 201-208. A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä
Nocturnal oxygen resaturation parameters are associated with cardiorespiratory comorbidities
Howarth, Timothy P; Sillanmäki, Saara; Karhu, Tuomas; Rissanen, Marika; Islind, Anna Sigridur; Hrubos-Strøm, Harald; de Chazal, Philip; Huovila, Juuso; Kainulainen, Samu; Leppänen, Timo, 2024, Sleep medicine, 118, 101-112. A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä
Verbal memory is linked to average oxygen saturation during sleep, not the apnea-hypopnea index nor novel hypoxic load variables
Thorisdottir, K; Hrubos-Strøm, H; Karhu, T; Nikkonen, S; Dammen, T; Nordhus, IH; Leppänen, T; Jónsdóttir, MK; Arnardottir, ES, 2024, Sleep medicine, 123, 29-36. A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä
Worsening hypoxic load impairs cardiorespiratory coupling
Hietakoste, Salla; Armanac-Julian, Pablo; Karhu, Tuomas; Bailon, Raquel; Sillanmaki, Saara; Toyras, Juha; Leppanen, Timo; Myllymaa, Sami; Kainulainen, Samu, 2024. Abstrakti
Acute cardiorespiratory coupling impairment in worsening sleep apnea-related intermittent hypoxemia
Hietakoste, Salla; Armanac-Julian, Pablo; Karhu, Tuomas; Bailon, Raquel; Sillanmäki, Saara; Töyräs, Juha; Leppänen, Timo; Myllymaa, Sami; Kainulainen, Samu, 2023, IEEE transactions on biomedical engineering, 71, 1, 326-333. A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä
Nocturnal hypoxic load in the evaluation of the progression of sleep apnea
Karhu, Tuomas, 2023, Publications of the University of Eastern Finland. Dissertations in Science, Forestry and Technology. G5 Artikkeliväitöskirja
Oxygen resaturation rate is significantly associated with objectively assessed excessive daytime sleepiness in suspected obstructive sleep apnoea patients
Howarth, Timothy P.; Karhu, Tuomas; Kainulainen, Samu; Chen, Xin; Mahamid, Alaa; Töyräs, Juha; Leppänen, Timo, 2023, Sleep medicine, 107, 171-178. A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä
Reaction time in psychomotor vigilance task is related to hypoxic load in males with sleep apnea
Pahari, Purbanka; Korkalainen, Henri; Karhu, Tuomas; Arnardottir, Erna Sif; Töyräs, Juha; Leppänen, Timo; Nikkonen, Sami, 2023, Journal of sleep research, 33, 2, e13988. A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä
Utilizing Envelope Analysis of a Nasal Pressure Signal for Sleep Apnea Severity Estimation
Varis, Mikke; Karhu, Tuomas; Leppänen, Timo; Nikkonen, Sami, 2023, Diagnostics, 13, 10, 1776. A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä
ABOSA – Freely available automatic blood oxygen saturation signal analysis software: Structure and validation
Karhu, Tuomas; Leppänen, Timo; Töyräs, Juha; Oksenberg, Arie; Myllymaa, Sami; Nikkonen, Sami, 2022, Computer methods and programs in biomedicine, 226, 107120. A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä
Desaturation event scoring criteria affect the perceived severity of nocturnal hypoxic load
Karhu, Tuomas; Leppänen, Timo; Korkalainen, Henri; Myllymaa, Sami; Duce, Brett; Töyräs, Juha; Nikkonen, Sami, 2022, Sleep medicine, 100, 479-486. A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä
Novel oxygen desaturation parameters are associated with cardiac troponin I: Data from the Akershus Sleep Apnea Project
Sigurdardottir, Fjola D.; Øverby, Caroline Tonje; Nikkonen, Sami; Karhu, Tuomas; Dammen, Toril; Nordhus, Inger Hilde; Thorshov, Thea; Einvik, Gunnar; Kainulainen, Samu; Leppänen, Timo; Arnardottir, Erna Sif; Töyräs, Juha; Omland, Torbjørn; Hrubos‐Strøm, Harald, 2022, Journal of sleep research, 31, 5, e13581. A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä
OSA-related respiratory events and desaturation severity are associated with the cardiac response
Hietakoste, Salla; Karhu, Tuomas; Sillanmäki, Saara; Bailón, Raquel; Penzel, Thomas; Töyräs, Juha; Leppänen, Timo; Myllymaa, Sami; Kainulainen, Samu, 2022, ERJ open research, 8, 4, 00121-2022. A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä
Obstructive sleep apnea‐related intermittent hypoxaemia is associated with impaired vigilance
Pahari, Purbanka; Korkalainen, Henri; Karhu, Tuomas; Rissanen, Marika; Arnardottir, Erna Sif; Hrubos‐Strøm, Harald; Duce, Brett; Töyräs, Juha; Leppänen, Timo; Nikkonen, Sami, 2022, Journal of sleep research, [First published: 08 December 2022], e13803. A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä
The severity and morphology of intermittent hypoxemias are related to impaired daytime alertness
Pahari, P; Korkalainen, H; Karhu, T; Rissanen, M; Arnardottir, ES; Strøm, HH; Duce, B; Töyräs, J; Leppänen, T; Nikkonen, S, 2022, Sleep medicine. Abstrakti
Diabetes and cardiovascular diseases are associated with the worsening of intermittent hypoxaemia
Karhu, T; Myllymaa, S; Nikkonen, S; Mazzotti, DR; Kulkas, A; Töyräs, J; Leppänen, T, 2021, Journal of sleep research, 2022; 31, 1, e13441. A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä
Longer and Deeper Desaturations Are Associated With the Worsening of Mild Sleep Apnea: The Sleep Heart Health Study
Karhu, Tuomas; Myllymaa, Sami; Nikkonen, Sami; Mazzotti, Diego R; Töyräs, Juha; Leppänen, Timo, 2021, Frontiers in neuroscience, 15, 657126. A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä

Tarkenna hakuasi

Tutkimusryhmät

Avainsanat

Differential associations of arousals and respiratory events on oxygen desaturation and resaturation parameters in sleep

Five-year longitudinal changes in oxygen saturation parameters in Obstructive Sleep Apnoea: Impact of age, body mass index, and comorbidities

RAVEN: Software for automated sleep microstructure analysis from electroencephalography

Nocturnal short-term HRV reflects impaired daytime vigilance better than overnight HRV in suspected OSA patients

Optimal Electroencephalogram and Electrooculogram Signal Combination for Deep Learning-based Sleep Staging

The interaction between comorbidities and sleep stages influences oxygen re‐saturation characteristics

A comparative analysis of unsupervised machine‐learning methods in PSG‐related phenotyping

Excessive daytime sleepiness is associated with relative delta frequency power among patients with mild OSA

Interhemispheric differences of electroencephalography signal characteristics in different sleep stages

Nocturnal oxygen resaturation parameters are associated with cardiorespiratory comorbidities

Verbal memory is linked to average oxygen saturation during sleep, not the apnea-hypopnea index nor novel hypoxic load variables

Worsening hypoxic load impairs cardiorespiratory coupling

Acute cardiorespiratory coupling impairment in worsening sleep apnea-related intermittent hypoxemia

Nocturnal hypoxic load in the evaluation of the progression of sleep apnea

Oxygen resaturation rate is significantly associated with objectively assessed excessive daytime sleepiness in suspected obstructive sleep apnoea patients

Reaction time in psychomotor vigilance task is related to hypoxic load in males with sleep apnea

Utilizing Envelope Analysis of a Nasal Pressure Signal for Sleep Apnea Severity Estimation

ABOSA – Freely available automatic blood oxygen saturation signal analysis software: Structure and validation

Desaturation event scoring criteria affect the perceived severity of nocturnal hypoxic load

Novel oxygen desaturation parameters are associated with cardiac troponin I: Data from the Akershus Sleep Apnea Project

OSA-related respiratory events and desaturation severity are associated with the cardiac response

Obstructive sleep apnea‐related intermittent hypoxaemia is associated with impaired vigilance

The severity and morphology of intermittent hypoxemias are related to impaired daytime alertness

Diabetes and cardiovascular diseases are associated with the worsening of intermittent hypoxaemia

Longer and Deeper Desaturations Are Associated With the Worsening of Mild Sleep Apnea: The Sleep Heart Health Study