Tuomas Rauramaa

Fagerlund, Ilkka; Dougalis, Antonios; Shakirzyanova, Anastasia; Gómez-Budia, Mireia; Pelkonen, Anssi; Konttinen, Henna; Ohtonen, Sohvi; Fazaludeen, Mohammad Feroze; Koskuvi, Marja; Kuusisto, Johanna; Hernández, Damián; Pebay, Alice; Koistinaho, Jari; Rauramaa, Tuomas; Lehtonen, Šárka; Korhonen, Paula; Malm, Tarja. 2021. Microglia-like Cells Promote Neuronal Functions in Cerebral Organoids Cells 2022; 11 1: 124. 2021

Sirkka, Jani; Parviainen, Marita; Jyrkkänen, Henna-Kaisa; Koivisto, Anne M.; Säisänen, Laura; Rauramaa, Tuomas; Leinonen, Ville; Danner, Nils. 2021. Upper limb dysfunction and activities in daily living in idiopathic normal pressure hydrocephalus Acta neurochirurgica 163 10: 2675-2683. 2021

Wittrahm, Rebekka; Takalo, Mari; Marttinen, Mikael; Kuulasmaa, Teemu; Mäkinen, Petra; Kemppainen, Susanna; Martiskainen, Henna; Rauramaa, Tuomas; Pike, Ian; Leinonen, Ville; Natunen, Teemu; Haapasalo, Annakaisa; Hiltunen, Mikko. 2021. MECP2 Increases the Pro-Inflammatory Response of Microglial Cells and Phosphorylation at Serine 423 Regulates Neuronal Gene Expression upon Neuroinflammation Cells 10 4: 860. 2021

Vanninen, Aleksi; Nakajima, Madoka; Miyajima, Masakazu; Rauramaa, Tuomas; Kokki, Merja; Musialowicz, Tadeusz; Mäkinen, Petra M; Herukka, Sanna-Kaisa; Koivisto, Anne M; Jääskeläinen, Juha E; Hiltunen, Mikko; Leinonen, Ville. 2021. Elevated CSF LRG and Decreased Alzheimer's Disease Biomarkers in Idiopathic Normal Pressure Hydrocephalus Journal of clinical medicine 10 5: 1105. 2021

Junkkari, A; Sintonen, H; Danner, N; Jyrkkänen, HK; Rauramaa, T; Luikku, AJ; Koivisto, AM; Roine, RP; Viinamäki, H; Soininen, H; Jääskeläinen, JE; Leinonen, V. 2021. 5-Year health-related quality of life outcome in patients with idiopathic normal pressure hydrocephalus Journal of neurology 268 9: 3283-3293. 2021

Nerg, Ossi; Junkkari, Antti; Hallikainen, Ilona; Rauramaa, Tuomas; Luikku, Antti; Hiltunen, Mikko; Jääskeläinen, Juha E.; Leinonen, Ville; Hänninen, Tuomo; Koivisto, Anne;. 2021. The CERAD Neuropsychological Battery in Patients with Idiopathic Normal Pressure Hydrocephalus Compared with Normal Population and Patients with Mild Alzheimer's Disease Journal of Alzheimer's disease 81 3: 1117-1130. 2021

Keränen, Sara; Suutarinen, Santeri; Mallick, Rahul; Laakkonen, Johanna P.; Guo, Diana; Pawlikowska, Ludmila; Jahromi, Behnam Rezai; Rauramaa, Tuomas; Ylä-Herttuala, Seppo; Marchuk, Doug; Krings, Timo; Koivisto, Timo; Lawton, Michael; Radovanovic, Ivan; Kim, Helen; Faughnan, Marie E.; Frösen, Juhana. 2021. Cyclo-oxygenase 2, a putative mediator of vessel remodeling, is expressed in the brain AVM vessels and associates with inflammation Acta neurochirurgica 163 9: 2503-2514. 2021

Lukkarinen, Heikki; Tesseur, Ina; Pemberton, Darrel; Van Der Ark, Peter; Timmers, Maarten; Slemmon, Randy; Janssens, Luc; Streffer, Johannes; Van Nueten, Luc; Bottelbergs, Astrid; Rauramaa, Tuomas; Koivisto, Anne M.; Herukka, Sanna-Kaisa; Korhonen, Ville E.; Junkkari, Antti; Hiltunen, Mikko; Engelborghs, Sebastiaan; Blennowk, Kaj; Zetterbergk, Henrik; Kolb, Hartmuth C.; Leinonen, Ville. 2021. Time Trends of Cerebrospinal Fluid Biomarkers of Neurodegeneration in Idiopathic Normal Pressure Hydrocephalus Journal of Alzheimer's disease 80 4: 1629-1642. 2021

Hallikainen, J; Keränen, S; Savolainen, J; Närhi, M; Suominen, AL; Ylöstalo, P; Kellokoski, J; Pyysalo, M; Pussinen, P; Rauramaa, T; Frösen, J. 2020. Role of oral pathogens in the pathogenesis of intracranial aneurysm: review of existing evidence and potential mechanisms Neurosurgical review 2021; 44: 239-247. 2020

Nakajima, Madoka; Rauramaa, Tuomas; Mäkinen, Petra M; Hiltunen, Mikko; Herukka, Sanna-Kaisa; Kokki, Merja; Musialowicz, Tadeusz; Jyrkkänen, Henna-Kaisa; Danner, Nils; Junkkari, Antti; Koivisto, Anne M; Jääskeläinen, Juha E; Miyajima, Masakazu; Ogino, Ikuko; Furuta, Akiko; Akiba, Chihiro; Kawamura, Kaito; Kamohara, Chihiro; Sugano, Hidenori; Tange, Yuichi; et al. [incl. Leinonen, Ville]. 2020. PTPR type Q in cerebrospinal fluid reflects ependymal cells dysfunction and is a potential biomarker for adult chronic hydrocephalus European journal of neurology 2021; 28 2: 389-400. 2020

Natunen, Teemu; Martiskainen, Henna; Marttinen, Mikael; Gabbouj, Sami; Koivisto, Hennariikka; Kemppainen, Susanna; Kaipainen, Satu; Takalo, Mari; Svobodová, Helena; Leppänen, Luukas; Kemiläinen, Benjam; Ryhänen, Simo; Kuulasmaa, Teemu: Rahunen, Eija: Juutinen, Sisko; Mäkinen, Petra; Miettinen, Pasi; Rauramaa, Tuomas; Pihlajamäki, Jussi; Haapasalo, Annakaisa; et al [incl. Leinonen, Ville; Tanila, H. 2020. Diabetic phenotype in mouse and humans reduces the number of microglia around ß-amyloid plaques Molecular neurodegeneration 15: 66. 2020

Wright, Roosa; Järvelin, Patrik; Pekonen, Henri; Keränen, Sara; Rauramaa, Tuomas; Frösen, Juhana. 2020. Histopathology of brain AVMs part II: inflammation in arteriovenous malformation of the brain Acta neurochirurgica 162 7: 1741-1747. 2020

Luikku, AJ; Hall, A; Nerg, O; Koivisto, AM; Hiltunen, M; Helisalmi, S; Herukka, SK; Junkkari, A; Sutela, A; Kojoukhova, M; Korhonen, V; Mattila, J; Lötjönen, J; Rummukainen, J; Alafuzoff, I; Jääskeläinen, JE; Remes, AM; Solomon, A; Kivipelto, M; Soininen, H; et al. [Incl. Rauramaa, T; Leinonen, V]. 2019. Predicting Development of Alzheimer's Disease in Patients with Shunted Idiopathic Normal Pressure Hydrocephalus Journal of Alzheimer's disease 71 4: 1233-1243. 2019

Taha, I: Hyvärinen, A; Ranta, A; Kämäräinen, OP; Huttunen, J; Mervaala, E; Löppönen, H; Rauramaa, T; Ronkainen, A; Jääskeläinen, JE; Immonen, A; Danner, N. 2019. Facial nerve function and hearing after microsurgical removal of sporadic vestibular schwannomas in a population-based cohort Acta neurochirurgica 2020; 162 1: 43-54. 2019

Rinne, JO; Suotunen, T; Rummukainen, J; Herukka, SK; Nerg, O; Koivisto, AM; Rauramaa, T; Någren, K; Hiltunen, M; Alafuzoff, I; Rinne, J; Jääskeläinen, JE; Soininen, H; Leinonen, V. 2019. [11C]PIB PET Is Associated with the Brain Biopsy Amyloid-ß Load in Subjects Examined for Normal Pressure Hydrocephalus Journal of Alzheimer's disease 67 4: 1343-1351. 2019

Minkeviciene R, Hlushchenko, I; Virenque, A; Lahti, L; Khanal, P; Rauramaa, T; Koistinen, A; Leinonen, V; Noe, FM; Hotulainen, P. 2019. MIM-Deficient Mice Exhibit Anatomical Changes in Dendritic Spines, Cortex Volume and Brain Ventricles, and Functional Changes in Motor Coordination and Learning Frontiers in molecular neuroscience 12: 276. 2019

Korhonen, VE; Remes, AM; Helisalmi, S; Rauramaa, T; Sutela, A; Vanninen, R; Suhonen, NM; Haapasalo, A; Hiltunen, M; Jääskeläinen, JE; Soininen, H; Koivisto, AM; Leinonen, V. 2019. Prevalence of C9ORF72 Expansion in a Large Series of Patients with Idiopathic Normal-Pressure Hydrocephalus Dementia and geriatric cognitive disorders 47 1-2: 91-103. 2019

Leinonen, Ville; Junkkari, Antti; Rauramaa, Tuomas; Jääskeläinen, Juha E; Vanninen, Ritva; Savolainen, Sakari; Hiltunen, Mikko; Remes, Anne M; Koivisto, Anne M. 2019. Normaalipaineisen hydrokefaluksen kliininen kuva, diagnostiset tutkimukset ja hoito Duodecim 135 3: 265-273. 2019

Kholová, Ivana; Aho, Heikki; Boström, Pia; Hagström, Jaana; Ikonen, Essi; Krogerus, Leena; Porre, Sinikka; Rauramaa, Tuomas; Rytkönen, Aleksi; Tarkkanen, Jussi; Tommola, Satu. 2019. Sylkirauhasten ohutneulanäytteille Milanon luokitus Lääkärilehti 74 12: 764-765. 2019

Junkkari, A; Luikku, A J; Danner, N; Jyrkkänen, H K; Rauramaa, T; Korhonen, V E; Koivisto, A M; Nerg, O; Kojoukhova, M; Huttunen, T J; Jääskeläinen, J E; Leinonen, V. 2019. The Kuopio idiopathic normal pressure hydrocephalus protocol: initial outcome of 175 patients Fluids and barriers of the cns 16: 21. 2019

Jeppsson, Anna; Wikkelsö, Carsten; Blennow, Kaj; Zetterberg, Henrik; Constantinescu, Radu; Remes, Anne M; Herukka, Sanna-Kaisa; Rauramaa, Tuomas; Nagga, Katarina; Leinonen, Ville; Tullberg, Mats. 2019. CSF biomarkers distinguish idiopathic normal pressure hydrocephalus from its mimics Journal of neurology neurosurgery and psychiatry 90 10: 1117-1123. 2019

Nikolaev, SI; Vetiska, S; Bonilla, X; Boudreau, E; Jauhiainen, S; Rezai, Jahromi B; Khyzha, N; DiStefano, PV; Suutarinen, S; Kiehl, TR; Mendes Pereira, V; Herman, AM; Krings, T; Andrade-Barazarte, H; Tung, T; Valiante, T; Zadeh, G; Tymianski, M; Rauramaa, T; Ylä-Herttuala, S et al.. 2018. Somatic Activating KRAS Mutations in Arteriovenous Malformations of the Brain. NEW ENGLAND JOURNAL OF MEDICINE 378 3: 250-261. 2018

Vanhala, V; Junkkari, A; Korhonen, VE; Kurki, MI; Hiltunen, M; Rauramaa, T;, Nerg, O;, Koivisto, AM; Remes, AM; Perälä, J; Suvisaari, J; Lehto, S; Viinamäki, H; Soininen, H; Jääskeläinen, JE; Leinonen, V. 2018. Prevalence of Schizophrenia in Idiopathic Normal Pressure Hydrocephalus Neurosurgery 2019; 84 4: 883-889. 2018

Rauramaa, T; Saxlin, A; Lohvansuu, K; Alafuzoff, I; Pitkänen, A; Soininen, H. 2018. Epilepsy in neuropathologically verified Alzheimer's disease. SEIZURE 58: 9-12. 2018

Pyykkö, OT; Nerg, O; Niskasaari, HM; Niskasaari, T; Koivisto, AM; Hiltunen, M; Pihlajamäki, J; Rauramaa, T; Kojoukhova, M; Alafuzoff, I; Soininen, H; Jääskeläinen, JE; Leinonen, V. 2018. Incidence, comorbidities, and mortality in idiopathic normal pressure hydrocephalus. WORLD NEUROSURGERY 112: e624-e631. 2018

Penttilä, Elina; Vanninen, Ritva; Voutilainen, Leena; Rauramaa, Tuomas; Immonen, Arto; Kantanen, Anne-Mari. 2018. Kollegan harvinainen aivosairaus SUOMEN LÄÄKÄRILEHTI 73 46: 2711-2715. 2018

Marttinen, M; Paananen, J; Neme, A; Mitra, V; Takalo, M; Natunen, T; Paldanius, KMA; Mäkinen, P; Bremang, M; Kurki, MI; Rauramaa, T; Leinonen, V; Soininen, H; Haapasalo, A; Pike, I; Hiltunen, M. 2018. A multiomic approach to characterize the temporal sequence in Alzheimer's disease-related pathology Neurobiology of disease 2019; 124: 454-468. 2018

Leinonen, V; Rauramaa, T; Johansson, J; Bottelbergs, A; Tesseur, I; van der Ark, P; Pemberton, D; Koivisto, AM; Jääskeläinen, JE; Hiltunen, M; Herukka, SK; Blennow, K; Zetterberg, H; Jokinen, P; Rokka, J; Helin, S; Haaparanta-Solin, M; Solin, O; Okamura, N; Kolb, HC; et al.. 2018. S-[18F]THK-5117-PET and [11C]PIB-PET Imaging in Idiopathic Normal Pressure Hydrocephalus in Relation to Confirmed Amyloid-ß Plaques and Tau in Brain Biopsies Journal of Alzheimer's Disease 64 1: 171-179. 2018

Leal, NS; Dentoni, G; Schreiner, B; Kämäräinen, OP; Partanen, N; Herukka, SK; Koivisto, AM; Hiltunen, M; Rauramaa, T; Leinonen, V; Ankarcrona, M. 2018. Alterations in mitochondria-endoplasmic reticulum connectivity in human brain biopsies from idiopathic normal pressure hydrocephalus patients Acta neuropathologica communications 6: 102. 2018

Anwer, M; Bolkvadze, T; Ndode-Ekane, XE; Puhakka, N; Rauramaa, T; Leinonen, V; van Vliet, EA; Swaab, DF; Haapasalo, A; Leskelä, S; Bister, N; Malm, T; Carlson, S; Aronica, E; Pitkänen, A. 2018. Sushi repeat-containing protein X-Linked 2 - a novel phylogenetically conserved hypothalamo-pituitary protein JOURNAL OF COMPARATIVE NEUROLOGY 526 11: 1806-1819. 2018

Leskelä, S; Takalo, M; Marttinen, M; Huber, N; Paananen, J; Mitra, V; Rauramaa, T; Mäkinen, P; Leinonen, V; Soininen, H; Pike, I; Remes, AM; Hiltunen, M; Haapasalo, A. 2018. Interrelationship between the Levels of C9orf72 and Amyloid-ß Protein Precursor and Amyloid-ß in Human Cells and Brain Samples Journal of Alzheimer's disease 62 1: 269-278. 2018

Huovinen J, Helisalmi S, Paananen J, Laiterä T, Kojoukhova M, Sutela A, Vanninen R, Laitinen M, Rauramaa T, Koivisto AM, Remes AM, Soininen H, Kurki M, Haapasalo A, Jääskeläinen JE, Hiltunen M, Leinonen V. 2017. Alzheimer's Disease-Related Polymorphisms in Shunt-Responsive Idiopathic Normal Pressure Hydrocephalus Journal of Alzheimer's disease 60 3: 1077-1085. 2017

Junkkari Antti, Roine Risto P, Luikku Antti, Rauramaa Tuomas, Sintonen Harri, Nerg Ossi, Koivisto Anne M, Häyrinen Antti, Viinamäki Heimo, Soininen Hilkka, Jääskeläinen Juha E, Leinonen Ville. 2017. Why does the health-related quality of life in idiopathic normal pressure hydrocephalus fail to improve despite the favorable clinical outcome?. WORLD NEUROSURGERY 108: 356-366. 2017

Korhonen VE, Solje E, Suhonen NM, Rauramaa T, Vanninen R, Remes AM, Leinonen V. 2017. Frontotemporal dementia as a comorbidity to idiopathic normal pressure hydrocephalus (iNPH): a short review of literature and an unusual case Fluids and barriers of the cns 14: 10. 2017

Leinonen V, Vanninen R, Rauramaa T. 2017. Cerebrospinal fluid circulation and hydrocephalus. Teoksessa: Kovacs Gabor G, Alafuzoff Irina (toim.) Handbook of Clinical Neurology. Neuropathology. Elsevier. Handbook of Clinical Neurology 145. s. 39-50. 2017

Leinonen V, Vanninen R, Rauramaa T. 2017. Raised intracranial pressure and brain edema. Teoksessa: Kovacs Gabor G, Alafuzoff Irina (toim.) Handbook of Clinical Neurology. Neuropathology. Elsevier. Handbook of Clinical Neurology 145. s. 25-37. 2017

Rauramaa Tuomas, Solomon Alina, Pikkarainen Maria, Kälviäinen Reetta, Alafuzoff Irina. 2017. Hippocampal Sclerosis and Epilepsy in Elderly Population. Journal of Alzheimers Disease & Parkinsonism 7 5: 384. 2017

Kurkinen Kaisa MA, Marttinen Mikael, Turner Laura, Natunen Teemu, Mäkinen Petra, Haapalinna Fanni, Sarajärvi Timo, Gabbouj Sami, Kurki Mitja, Paananen Jussi, Koivisto Anne M, Rauramaa Tuomas, Leinonen Ville, Tanila Hanila, Soininen Hilkka, Lucas Fiona R, Haapasalo Annakaisa, Hiltunen Mikko. 2016. SEPT8 modulates ß-amyloidogenic processing of APP by affecting the sorting and accumulation of BACE1. JOURNAL OF CELL SCIENCE 129: 2224-2238. 2016

Laiterä Tiina, Paananen Jussi, Helisalmi Seppo, Sarajärvi Timo, Huovinen Joel, Laitinen Marjo, Rauramaa Tuomas, Alafuzoff Irina, Remes Anne M, Soininen Hilkka, Haapasalo Annakaisa, Jääskeläinen Juha E, Leinonen Ville, Hiltunen Mikko. 2016. Effects of Alzheimer's Disease-Associated Risk Loci on Amyloid-ß Accumulation in the Brain of Idiopathic Normal Pressure Hydrocephalus Patients. Journal of Alzheimer's Disease 2017; 55 3: 995-1003. 2016

Kojoukhova Maria, Vanha Krista-Irina, Timonen Matti, Koivisto Anne M, Nerg Ossi, Rummukainen Jaana, Rauramaa Tuomas, Vanninen Ritva, Jääskeläinen Juha E, Sutela Anna, Leinonen Ville. 2016. Associations of intracranial pressure with brain biopsy, radiological findings, and shunt surgery outcome in patients with suspected idiopathic normal pressure hydrocephalus Acta neurochirurgica 2017; 159 1: 51-61. 2016

Junkkari A, Häyrinen A, Rauramaa T, Sintonen H, Nerg O, Koivisto AM, Roine RP, Viinamäki H, Soininen H, Luikku A, Jääskeläinen JE, Leinonen V. 2016. Health-related quality-of-life outcome in patients with idiopathic normal-pressure hydrocephalus - a 1-year follow-up study. EUROPEAN JOURNAL OF NEUROLOGY 24 1: 58-66. 2016

Natunen Teemu, Takalo Mari, Kemppainen Ssusanna, Leskelä Stina, Marttinen Mikael, Kurkinen Kaisa MA, Pursiheimo Juha-Pekka, Sarajärvi Timo, Viswanathan Jayashree, Gabbouj Sami, Solje Eino, Tahvanainen Eveliina, Pirttimäki Tiina, Kurki Mitja, Paananen Jussi, Rauramaa Tuomas, Miettinen Pasi, Mäkinen Petra, Leinonen Ville, Soininen Hilkka et al. 2015. Relationship between ubiquilin-1 and BACE1 in human Alzheimer's disease and APdE9 transgenic mouse brain and cell-based models Neurobiology of disease 2016; 85: 187-205. 2015

Rauramaa Tuomas. 2015. Hippocampal lesions in aged populations: neuropathological and epidemiological studies. Itä-Suomen yliopisto. Publications of the University of Eastern Finland. Dissertations in Health Sciences 321. 2015

Sarajärvi Timo, Marttinen Mikael, Natunen Teemu, Kauppinen Tarja, Mäkinen Petra, Helisalmi Seppo, Laitinen Marjo, Rauramaa Tuomas, Leinonen Ville, Petäjä-Repo Ulla, Soininen Hilkka, Haapasalo Annakaisa, Hiltunen Mikko. 2015. Genetic Variation in delta-Opioid Receptor Associates with Increased ß- and gamma-Secretase Activity in the Late Stages of Alzheimer's Disease. Journal of Alzheimer's Disease 48 2: 507-516. 2015

Laiterä T, Sarajärvi T, Haapasalo A, Puli L, Kauppinen T, Mäkinen P, Rauramaa T, Tanila H, Jääskeläinen JE, Alafuzoff I, Soininen H, Leinonen V, Hiltunen M. 2014. Increased y-Secretase Activity in Idiopathic Normal Pressure Hydrocephalus Patients with b-Amyloid Pathology. PLOS ONE [ONLINE] 3 9: e93717: 1-8. 2014

Martiskainen H, Viswanathan J, Nykänen NP, Kurki M, Helisalmi S, Natunen T, Sarajärvi T, Kurkinen KM, Pursiheimo JP, Rauramaa T, Alafuzoff I, Jääskeläinen JE, Leinonen V, Soininen H, Haapasalo A, Huttunen HJ, Hiltunen M. 2014. Transcriptomics and mechanistic elucidation of Alzheimer's disease risk genes in the brain and in vitro models. NEUROBIOLOGY OF AGING 36 2: 1221.e15-1221.e28. 2014

Natunen Teemu, Martiskainen Henna, Sarajärvi Timo, Helisalmi Seppo, Pursiheimo Juha-Pekka, Viswanathan Jayashree, Laitinen Marjo, Kauppinen Tarja, Rauramaa Tuomas, Leinonen Ville, Alafuzoff Irina, Haapasalo Annakaisa, Soininen Hilkka, Hiltunen Mikko. 2013. Effects of NR1H3 genetic variation on the expression of liver X receptor alfa and the progression of Alzheimer's Disease. PLOS ONE [ONLINE] 8 11: e80700. 2013

Rauramaa T, Pikkarainen M, Englund E, Ince PG, Jellinger K, Paetau A, Alafuzoff I. 2013. Consensus recommendations on pathologic changes in the hippocampus: A postmortem multicenter inter-rater study. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (LAWRENCE KS) 72 6: 452-461. 2013

Rauramaa T, Pikkarainen M, Englund E, Ince PG, Jellinger K, Paetau A, Alafuzoff I. 2011. TAR-DNA binding protein-43 and anterations in the hippocampus. JOURNAL OF NEURAL TRANSMISSION 118: 683-689. 2011

Rauramaa T, Pikkarainen M, Englund E, Ince PG, Jellinger K, Paetau A, Parkkinen L, Alafuzoff I. 2011. Cardiovascular diseases and hippocampal infarcts. HIPPOCAMPUS 21: 281-287. 2011

Rauramaa T, Pulkkinen J, Miettinen P, Kainulainen S, Seppä A & Kärjä V. 2010. Case report: osteoclast-like giant cell tumos of the pancreas without epithelial differentiation JOURNAL OF CLINICAL PATHOLOGY 63 4: 376-377. 2010

Komulainen P, Pedersen M, Hänninen T, Bruunsgaard H, Lakka TA, Kivipelto M, Hassinen M, Rauramaa TH, Pedersen BK, Rauramaa R. 2008. BDNF is a novel marker of cognitive function in ageing women: the DR's EXTRA Study. NEUROBIOLOGY OF LEARNING AND MEMORY 90 4: 596-603. 2008

Savonen KP, Kiviniemi V, Laukkanen JA, Lakka TA, Rauramaa TH, Salonen JT, Rauramaa R. 2008. Chronotropic incompetence and mortality in middle-aged men with known or suspected coronary heart disease. EUROPEAN HEART JOURNAL 29 15: 1896-1902. 2008

Savonen KP, Lakka TA, Laukkanen JA, Rauramaa TH, Salonen JT, Rauramaa R. 2008. Usefulness of chronotropic incompetence in response to exercise as a predictor of myocardial infarction in middle-aged men without cardiovascular disease. AMERICAN JOURNAL OF CARDIOLOGY 101: 992-998. 2008

Savonen KP, Lakka TA, Laukkanen JA, Rauramaa TH, Salonen JT, Rauramaa R. 2008. Workload at the heart rate of 100 beats/min and mortality in middle-aged men known or suspected coronary heart disease. Heart 94: E14. 2008

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