
Tuomo Laitinen
Erikoistutkija
Terveystieteiden tiedekunta, Farmasian laitos
tuomo.laitinen@uef.fi | 040 016 5489
Tietokoneavusteisen lääkeainesuunnittelun dosentti
Julkaisut
66 kappaletta-
BCKDK: an emerging kinase target for metabolic diseases and cancer
East, Michael P; Laitinen, Tuomo; Asquith, Christopher RM. Nature reviews drug discovery 20 7: 498. 2021 -
Synthesis and Evaluation of Novel 1,2,6-Thiadiazinone Kinase Inhibitors as Potent Inhibitors of Solid Tumors
Kalogirou, Andreas S.; East, Michael P.; Laitinen, Tuomo; Torrice, Chad D.; Maffuid, Kaitlyn A.; Drewry, David H.; Koutentis, Panayiotis A.; Johnson, Gary L.; Crona, Daniel J.; Asquith, Christopher R. M.. Molecules 26 19: 5911. 2021 -
Molecular characteristics supporting L-Type amino acid transporter 1 (LAT1)-mediated translocation
Kärkkäinen, Jussi; Laitinen, Tuomo; Markowicz-Piasecka, Magdalena; Montaser, Ahmed; Lehtonen, Marko; Rautio, Jarkko; Gynther, Mikko; Poso, Antti; Huttunen, Kristiina M. Bioorganic chemistry 112: 104921. 2021 -
SARS-CoV-2--host proteome interactions for antiviral drug discovery
Liu, Xiaonan; Huuskonen, Sini; Laitinen, Tuomo; Redchuk, Taras; Bogacheva, Mariia; Salokas, Kari; Pöhner, Ina; Öhman, Tiina; Tonduru, Arun Kumar; Hassinen, Antti; Gawriyski, Lisa; Keskitalo, Salla; Vartiainen, Maria K.; Pietiäinen, Vilja; Poso, Antti; Varjosalo, Markku. Molecular systems biology 17 11: e10396. 2021 -
Structural Characterization of LsrK as a Quorum Sensing Target and a Comparison between X-ray and Homology Models
Medarametla, Prasanthi; Kronenberger, Thales; Laitinen, Tuomo; Poso, Antti. Journal of chemical information and modeling 61 3: 1346-1353. 2021 -
Identification of Key Amino Acids that Impact Organic Solute Transporter Alpha/Beta (OSTα/ß)
Murphy, William A.; Beaudoin, James J.; Laitinen, Tuomo; Sjöstedt, Noora; Malinen, Melina M.; Ho, Henry; Swaan, Peter W.; Honkakoski, Paavo; Brouwer, Kim L.R.. Molecular pharmacology 100 6: 599-608. 2021 -
In vitro identification and in vivo confirmation of inhibitors for SPCSV RNA silencing suppressor, a viral RNase III
Wang, Linping; Poque, Sylvain; Laamanen, Karoliina; Saarela, Jani; Poso, Antti; Laitinen, Tuomo; Valkonen, Jari PT. Journal of virology 95 12: e00107-21. 2021 -
Docking-Based 3D-QSAR Studies for 1,3,4-oxadiazol-2-one Derivatives as FAAH Inhibitors
Zieba, Agata; Laitinen, Tuomo; Patel, Jayendra Z.; Poso, Antti; Kaczor, Agnieszka A.. International journal of molecular sciences 22 11: 6108. 2021 -
Targeting the water network in cyclin G associated kinase (GAK) with 4-anilino-quin(az)oline inhibitors
Asquith, Christopher Robert Michael; Tizzard, Graham J; Bennett, James M; Wells, Carrow I; Elkins, Jonathan M; Willson, Timothy M; Poso, Antti; Laitinen, Tuomo. Chemmedchem 15 13: 1200-1215. 2020 -
New Insights into 4-Anilinoquinazolines as Inhibitors of Cardiac Troponin I-Interacting Kinase (TNNi3K)
Asquith, Christopher; Laitinen, Tuomo; Wells, Carrow; Tizzard, Graham; Zuercher, William. Molecules 25 7: 1697. 2020