Nutrigenomics and molecular nutrition

Cost-Effectiveness of Passion Fruit Albedo versus Turmeric in the Glycemic and Lipaemic Control of People with Type 2 Diabetes: Randomized Clinical Trial

Sousa, Danilo Ferreira de; Araújo, Márcio Flávio Moura de; de Mello, Vanessa Derenji; Damasceno, Marta Maria Coelho; Freitas, Roberto Wagner Júnior Freire de. 2020. Journal of the american college of nutrition. 2021; 40: 679-688 A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä

Intake of Camelina Sativa Oil and Fatty Fish Alter the Plasma Lipid Mediator Profile in Subjects with Impaired Glucose Metabolism - A Randomized Controlled Trial

Meuronen, Topi; Lankinen, Maria A; Fauland, Alexander; Shimizu, Bun-Ichi; de Mello, Vanessa D; Laaksonen, David E; Wheelock, Craig E; Erkkilä, Arja T; Schwab, Ursula S. 2020. Prostaglandins leukotrienes and essential fatty acids. 159: 102143 A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä

Serum aromatic and branched-chain amino acids associated with NASH demonstrate divergent associations with serum lipids

de Mello, Vanessa D; Sehgal, Ratika; Männistö, Ville; Klåvus, Anton; Nilsson, Emma; Perfilyev, Alexander; Kaminska, Dorota; Miao, Zong; Pajukanta, Päivi; Ling, Charlotte; Hanhineva, Kati; Pihlajamäki, Jussi. 2020. Liver international. 2021; 41: 754-763 A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä

An Isocaloric Nordic Diet Modulates RELA and TNFRSF1A Gene Expression in Peripheral Blood Mononuclear Cells in Individuals with Metabolic Syndrome-A SYSDIET Sub-Study

Ulven, SM; Holven, KB; Rundblad, A; Myhrstad, MCW; Leder, L; Dahlman, I; Mello, VD; Schwab, U; Carlberg, C; Pihlajamäki, J; Hermansen, K; Dragsted, LO; Gunnarsdottir, I; Cloetens, L; Åkesson, B; Rosqvist, F; Hukkanen, J; Herzig, KH; Savolainen, MJ; Risérus, U; et al. [incl. Uusitupa, M]. 2019. Nutrients. 11: 2932 A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä

Camelina sativa Oil, Fatty Fish, and Lean Fish Do Not Markedly Affect Urinary Prostanoids in Subjects with Impaired Glucose Metabolism

Erkkilä, AT; Lee, JC; Lankinen, M; Manninen, S; Leung ,HH; Oger, C; de Mello, VD; Schwab, US. 2019. Lipids. 54: 453-464 A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä

Healthy Nordic Diet Modulates the Expression of Genes Related to Mitochondrial Function and Immune Response in Peripheral Blood Mononuclear Cells from Subjects with the Metabolic Syndrome - A SYSDIET Sub-Study

Myhrstad, MC; de Mello, VD; Dahlman, I; Kolehmainen, M; Paananen, J; Rundblad, A; Carlberg, C; Olstad, OK; Pihlajamäki, J; Holven, KB; Hermansen, K; Dragsted, LO; Gunnarsdottir, I; Cloetens, L; Storm, MU; Åkesson, B; Rosqvist, F; Hukkanen, J; et al. (incl. Schwab, U; Uusitupa, M). 2019. Molecular nutrition and food research. 63: 1801405 A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä

Liver DNA methylation of FADS2 associates with FADS2 genotypex

Walle, P; Männistö, V; de Mello, VD; Vaittinen, M; Perfilyev, A; Hanhineva, K; Ling, C; Pihlajamäki, J. 2019. Clinical epigenetics. 11: 10 A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä

The effect of different sources of fish and camelina sativa oil on immune cell and adipose tissue mRNA expression in subjects with abnormal fasting glucose metabolism: a randomized controlled trial

de Mello, VD; Dahlman, I; Lankinen, M; Kurl, S; Pitkänen, L; Laaksonen, DE; Schwab, US; Erkkilä, AT. 2019. Nutrition and diabetes. 9: 1 A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä

Total liver phosphatidylcholine content associates with non-alcoholic steatohepatitis and glycine N-methyltransferase expression

Männistö, V; Kaminska, D; Kärjä, V; Tiainen, M; de Mello, VD; Hanhineva, K; Soininen, P; Ala-Korpela, M; Pihlajamäki, J. 2019. Liver international. 39: 1895-1905 A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä

Associations of serum indolepropionic acid, a gut microbiota metabolite, with type 2 diabetes and low-grade inflammation in high-risk individuals

Tuomainen, Marjo; Lindström, Jaana; Lehtonen, Marko; Auriola, Seppo; Pihlajamäki, Jussi; Peltonen, Markku; Tuomilehto, Jaakko; Uusitupa, Matti; de Mello, Vanessa D; Hanhineva, Kati. 2018. Nutrition and diabetes. 8: 35 A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä

Camelina Sativa Oil, but not Fatty Fish or Lean Fish Improved Serum Lipid Profile in Subjects with Impaired Glucose Metabolism - a Randomized Controlled Trial

Schwab, US; Lankinen, MA; de Mello, VD; Manninen, SM; Kurl, S; Pulkki, KJ; Laaksonen, DE; Erkkilä, AT. 2018. Molecular nutrition and food research. 62: 1700503 A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä

Intake of Fatty Fish Alters the Size and the Concentration of Lipid Components of HDL Particles and Camelina Sativa Oil Decreases IDL Particle Concentration in Subjects with Impaired Glucose Metabolism

Manninen, Suvi M; Lankinen, Maria A; de Mello, Vanessa D; Laaksonen, David E; Schwab, Ursula S; Erkkilä, Arja T. 2018. Molecular nutrition and food research. 62: 1701042 A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä

Serum Adiponectin/Ferritin Ratio in Relation to the Risk of Type 2 diabetes and Insulin Sensitivity

Aregbesola, A; de Mello, VDF; Lindström, J; Voutilainen, S; Virtanen, JK; Keinänen-Kiukaanniemi, S; Tuomainen, TP; Tuomilehto, J; Uusitupa, M. 2018. Diabetes research and clinical practice. 141: 264-274 A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä

Serum, liver and bile sitosterol and sitostanol in obese patients with and without NAFLD

Tauriainen, Milla-Maria; Männistö, Ville; Kaminska, Dorota; Vaittinen, Maija; Kärjä, Vesa; Käkelä, Pirjo; Venesmaa, Sari; Gylling, Helena; Pihlajamäki, Jussi. 2018. Bioscience reports. 38: 1-9 A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä

Sex Differences in the Methylome and Transcriptome of the Human Liver and Circulating HDL-Cholesterol Levels

García-Calzón, Sonia; Perfilyev, Alexander; de Mello, Vanessa D; Pihlajamäki, Jussi; Ling, Charlotte. 2018. Journal of clinical endocrinology and metabolism. 103: 4395-4408 A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä

The effect of camelina sativa oil and fish intakes on fatty acid compositions of blood lipid fractions

Manninen, S; Lankinen, M; de Mello, V; Ågren, J; Laaksonen, D; Schwab, U; Erkkilä, A. 2018. Nutrition metabolism and cardiovascular diseases. 2019; 29: 51-61 A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä

Diabetes medication associates with DNA methylation of metformin transporter genes in the human liver

García-Calzón Sonia, Perfilyev Alexander, Männistö Ville, de Mello Vanessa D, Nilsson Emma, Pihlajamäki Jussi, Ling Charlotte. 2017. Clinical epigenetics. 9: 102 A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä

Fasting serum hippuric acid is elevated after bilberry (Vaccinium myrtillus) consumption and associates with improvement of fasting glucose levels and insulin secretion in persons at high risk of developing type 2 diabetes

de Mello VD, Lankinen MA, Lindström J, Puupponen-Pimiä R, Laaksonen DE, Pihlajamäki J, Lehtonen M, Uusitupa M, Tuomilehto J, Kolehmainen M, Törrönen R, Hanhineva K. 2017. Molecular nutrition and food research. 61: 1700019 A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä

Indolepropionic acid and novel lipid metabolites are associated with a lower risk of type 2 diabetes in the Finnish Diabetes Prevention Study

de Mello VD, Paananen J, Lindstrom J, Lankinen MA, Shi L, Kuusisto J, Pihlajamaki J, Auriola S, Lehtonen M, Rolandsson O, Bergdahl IA, Nordin E, Ilanne-Parikka P, Keinänen-Kiukaanniemi S, Landberg R, Eriksson JG, Tuomilehto J, Hanhineva K, Uusitupa M. 2017. Scientific reports. 7: 46337 A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä

DNA methylation of loci within ABCG1 and PHOSPHO1 in blood DNA is associated with future type 2 diabetes risk

Dayeh T, Tuomi T, Almgren P, Perfilyev A, Jansson PA, de Mello VD, Pihlajamäki J, Vaag A, Groop L, Nilsson E, Ling C. 2016. Epigenetics. 11: 482-488 A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä

Effect of a 2-y dietary and physical activity intervention on plasma fatty acid composition and estimated desaturase and elongase activities in children: the Physical Activity and Nutrition in Children Study

Venäläinen Taisa M, Viitasalo Anna M, Schwab Ursula S, Eloranta Aino-Maija, Haapala Eero A, Jalkanen Henna P, de Mello Vanessa DF, Laaksonen David E, Lindi Virpi I, Ågren Jyrki J, Lakka Timo A. 2016. American journal of clinical nutrition. 104: 964-972 A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä

Effects of a healthy Nordic diet on gene expression changes in peripheral blood mononuclear cells in response to an oral glucose tolerance test in subjects with metabolic syndrome: a SYSDIET sub-study

Leder Lena, Kolehmainen Marjukka, Narverud Ingunn, Dahlman Ingrid, Myhrstad Mari CW, de Mello Vanessa D, Paananen Jussi, Carlberg Castren, Schwab Ursula, Herzig Karl-Heinz, Cloetens Lieselotte, Storm Matilda Ulmius, Hukkanen Janne, Savolainen Markku J, Rosqvist Fredrik, Hermansen Kjeld, Dragsted Lars O, Gunnarsdottir Ingibjörk, Thorsdottir Inga, Risérus Ulf et al.. 2016. Genes and nutrition. 11: 1-13 A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä

Epigenetic alterations in blood mirror age-associated DNA methylation and gene expression changes in human liver

Bysani M, Perfilyev A, de Mello VD, Rönn T, Nilsson E, Pihlajamäki J, Ling C. 2016. Epigenomics. 2017; 9: 105-122 A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä

Reduction in cardiometabolic risk factors by a multifunctional diet is mediated via several branches of metabolism as evidenced by non-targeted metabolite profiling approach

Tovar Juscelino, de Mello Vanessa D, Nilsson Anne, Johansson Maria, Paananen Jussi, Lehtonen Marko, Hanhineva Kati, Björck Inger. 2016. Molecular nutrition and food research. [Epub ahead of print 8 Nov 2016]: 1-12 A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä

Cross-sectional associations of plasma fatty acid composition and estimated desaturase and elongase activities with cardiometabolic risk in Finnish children - The PANIC study

Venäläinen Taisa, Ågren Jyrki, Schwab Ursula, de Mello Vanessa D, Eloranta Aino-Maija, Laaksonen David E, Lindi Virpi, Lakka Timo A. 2015. Journal of clinical lipidology. 2016; 10: 82-91 A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä

Epigenetic alterations in human liver from subjects with type 2 diabetes in parallel with reduced folate levels

Nilsson Emma, Matte Ashok, Perfilyev Alexander, de Mello Vanessa D, Käkelä Pirjo, Pihlajamäki Jussi, Ling Charlotte. 2015. Journal of clinical endocrinology and metabolism. [epub ahead of p rint Sep 29, 2015]: - A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä

Gene-diet interaction of a common FADS1 variant with marine polyunsaturated fatty acids for fatty acid composition in plasma and erythrocytes among men

Takkunen Markus J, de Mello Vanessa D, Schwab Ursula S, Kuusisto Johanna, Vaittinen Maija, Ågren Jyrki J, Laakso Markku, Pihlajamäki Jussi, Uusitupa MI. 2015. Molecular nutrition and food research. 2016; 60: 381-389 A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä

Glucose Metabolism Effects of Vitamin D in Prediabetes: the VitDmet Randomized Placebo-Controlled Supplementation Study

Tuomainen Tomi-Pekka, Virtanen Jyrki K, Voutilainen Sari, Nurmi Tarja, Mursu Jaakko, de Mello Vanessa DF, Schwab Ursula, Hakumäki Martti, Pulkki Kari, Uusitupa Matti. 2015. Journal of Diabetes Research. 2015: 8 pages A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä

Longitudinal associations of serum fatty acid composition with type 2 diabetes risk and markers of insulin secretion and sensitivity in the Finnish Diabetes Prevention Study

Takkunen Markus J, Schwab Ursula S, de Mello Vanessa DF, Eriksson Johan G, Lindström Jaana, Tuomilehto Jaakko, Uusitupa Matti IJ, the DPS Study Group. 2015. European journal of nutrition. 2016; 55: 967-979 A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä

Markers of cholesterol metabolism as biomarkers in predicting diabetes in the Finnish Diabetes Prevention Study

de Mello VDF, Lindström J, Eriksson JG, Ilanne-Parikka P, Keinänen-Kiukaanniemi S, Pihlajamäki J, Tuomilehto J, Uusitupa M. 2015. Nutrition metabolism and cardiovascular diseases. 25: 635-642 A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä

Relevance of Vitamin D Receptor Target Genes for Monitoring the Vitamin D Responsiveness of Primary Human Cells

Vukic Maja, Neme Antonio, Seuter Sabine, Saksa Noora, de Mello Vanessa DF, Nurmi Tarja, Uusitupa Matti, Tuomainen Tomi-Pekka, Virtanen Jyrki K, Carlberg Carsten. 2015. PLoS ONE. 10: e0124339 A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä

Associations of erythrocyte membrane fatty acids with the concentrations of C-reactive protein, interleukin 1 receptor antagonist and adiponectin in1373 men

Takkunen MJ, de Mello VDF, Schwab US, Ågren JJ, Kuusisto J, Uusitupa MIJ. 2014. Prostaglandins leukotrienes and essential fatty acids. 91: 169-174 A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä

Changes in vitamin D target gene expression in adipose tissue monitor the vitamin D response of human individuals

Ryynänen Jussi, Neme Antonio, Tuomainen Tomi-Pekka, Virtanen Jyrki K, Voutilainen Sari, Nurmi Tarja, de Mello Vanessa DF, Uusitupa Matti, Carlberg Carsten. 2014. Molecular nutrition and food research. 58: 2036-2045 A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä

Cross-Sectional Associations of Food Consumption with Plasma Fatty Acid Composition and Estimated Desaturase Activities in Finnish Children

Venäläinen Taisa, Schwab Ursula, Ågren Jyrki, de Mello Vanessa, Lindi Virpi, Eloranta Aino-Maija, Kiiskinen Sanna, Laaksonen David, Lakka Timo A. 2014. Lipids. 49: 467-479 A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä

DNA methylation in obesity and type 2 diabetes

de Mello Vanessa Derenji Ferreira, Pulkkinen Leena, Lalli Marianne, Kolehmainen Marjukka, Pihlajamäki Jussi, Uusitupa Matti. 2014. Annals of medicine. 46: 103-113 A2 Katsausartikkeli tieteellisessä aikakauslehdessä

Dissecting high from low responders in a vitamin D3 intervention study

Saksa Noora, Neme Antonio, Ryynänen Jussi, Uusitupa Matti, de Mello Vanessa DF, Voutilainen Sari, Nurmi Tarja, Virtanen Jyrki K, Tuomainen Tomi-Pekka, Carlberg Carsten. 2014. Journal of steroid biochemistry and molecular biology. Epub ahead of print: - A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä

Healthy Nordic diet downregulates the expression of genes involved in inflammation in subcutaneous adipose tissue in individuals with features of the metabolic syndrome

Kolehmainen Marjukka, Ulven Stine M, Paananen Jussi, de Mello Vanessa, Schwab Ursula, Carlberg Carsten, Myhrstad Mari, Pihlajamäki Jussi, Dungner Elisabeth, Sjölin Eva, Gunnarsdottir Ingibjörg, Cloetens Lieselotte, Landin-Olsson Mona, Akesson Björn, Rosqvist Fredrik, Hukkanen Janne, Herzig Karl-Heinz, Dragsted Lars O, Savolainen Markku J, Brader Lea, Hermansen Kjeld, Risérus Ulf, Thorsdottir Inga, Poutanen Kaisa S, Uusitupa Matti, Arner Peter, Dahlman Ingrid. 2014. American journal of clinical nutrition. 101: 228-239 A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä

Nontargeted metabolite profiling discriminates diet-specific biomarkers for consumption of whole grains, fatty fish, and bilberries in a randomized controlled trial

Hanhineva Kati, Lankinen Maria A, Pedret Anna, Schwab Ursula, Kolehmainen Marjukka, Paananen Jussi, de Mello Vanessa, Sola Rosa, Lehtonen Marko, Poutanen Kaisa, Uusitupa Matti, Mykkänen Hannu. 2014. Journal of nutrition. 2015; 145: 7-17 A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä

Primary vitamin D receptor target genes as biomarkers for the vitamin D3 status in the hematopoietic system

Wilfinger Julia, Seuter Sabine, Tuomainen Tomi-Pekka, Virtanen Jyrki K, Voutilainen Sari, Nurmi Tarja, de Mello Vanessa DF, Uusitupa Matti, Carlberg Carsten. 2014. Journal of nutritional biochemistry. 25: 875-884 A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä

Effect of fatty and lean fish intake on lipoprotein subclasses in subjects with coronary heart disease: A controlled trial

Erkkilä AT, Schwab US, Lehto S, de Mello VD, Kangas AJ, Soininen P, Ala-Korpela M, Uusitupa MIJ. 2013. Journal of clinical lipidology. online: - A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä

Primary vitamin D target genes allow a categorization of possible benefits of vitamin D3 supplementation

Carlberg C, Seuter S, de Mello VDF, Schwab U, Voutilainen S, Pulkki K, Nurmi T, Virtanen J, Tuomainen T-P, Uusitupa M. 2013. PLoS ONE. 8: e71042 A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä

Gene expression of peripheral blood mononuclear cells as a tool in dietary intervention studies: What do we know so far?

de Mello VDF, Kolehmainen M, Schwab U, Pulkkinen L, Uusitupa M. 2012. Molecular nutrition and food research. 56: 1160-1172 A2 Katsausartikkeli tieteellisessä aikakauslehdessä

Insulin secretion and its determinants in the progression of impaired glucose tolerance to type 2 diabetes in impaired glucose-tolerant individuals: the finnish diabetes prevention study

de Mello Laaksonen VD, Lindström J, Eriksson J, Ilanne-Parikka P, Keinänen-Kiukaanniemi S, Sundvall J, Laakso M, Tuomilehto J, Uusitupa M. 2012. Diabetes care. 35: 211-217 A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä

Leukocyte Telomere Lenght in the Finnish Diabetes Prevention Study

Hovatta I, de Mello VDF, Kananen L, Lindström J, Eriksson JG, Ilanne-Parikka P, Keinänen-Kiukaanniemi S, Peltonen M, Tuomilehto J, Uusitupa M. 2012. PLoS ONE. 7: 1-6 A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä

A diet high in fatty fish, bilberries and wholegrain products improves markers of endothelial function and inflammation in individuals with impaired glucose metabolism in a randomised controlled trial: The Sysdimet study

de Mello Vanessa D, Schwab Ursula, Kolehmainen Marjukka, Koenig W, Siloaho Maritta, Poutanen Kaisa, Mykkänen Hannu, Uusitupa Matti. 2011. Diabetologia. 54: 2755-2767 A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä

High dietary glycemic index and low fiber content are associated with metabolic syndrome in patients with type 2 diabetes

Silva FM, Steemburgo T, de Mello VD, Tonding SF, Gross JL, Azevedo MJ. 2011. Journal of the american college of nutrition. 30: 141-148 A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä

Gene Expression of FTO in Human Subcutaneous Adipose Tissue, Peripheral Blood Mononuclear Cells and Adipocyte Cell Line.

Lappalainen T, Kolehmainen M, Schwab U, Pulkkinen L, de Mello VD, Vaittinen M, Laaksonen DE, Poutanen K, Uusitupa M, Gylling H. 2010. Journal of nutrigenetics and nutrigenomics. 3: 37-45 A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä

Fibras na dieta: tendencias atuais e benefícios à saúde na síndrome metabólica e no diabetes melito tipo 2. Dietary fibers: current trents and health benefits in the metabolic syndrome and type 2 diabetes

De Mello VD, Laaksonen DE. 2009. Arquivos brasileiros de endocrinologia e metabologia. 53: 509-518 A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä

Link between plasma ceramides, inflammation and insulin resistance: association with serum IL-6 concentration in patients with coronary heart disease

De Mello VDF, Lankinen M, Schwab U, Kolehmainen M, Lehto S, Seppä-Laakso T, Oresic M, Pulkkinen L, Uusitupa M, Erkkilä AT, De Mello VDF, Lankinen M, Schwab U, Kolehmainen M, Pulkkinen L, Uusitupa M. 2009. Diabetologia. 52: 2612-2615 A2 Katsausartikkeli tieteellisessä aikakauslehdessä

Papel do indice glimemico e da carga glicemica na prevencao e no controle metabolico de pacientes com daibetes melito tipo 2.Glycemic index and glycemic load in the prevention and treatment of type 2 diabetes mellitus

Silva FM, Steemburgo T, De Azevedo MJ, De Mello VD. 2009. Arquivos brasileiros de endocrinologia e metabologia. 53: 560-571 A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä

The effect of fatty or lean fish intake on inflammatory gene expression in peripheral blood mononuclear cells of patients with coronary heart disease

De Mello VDF, Erkkilä AT, Schwab US, Pulkkinen L, Kolehmainen M, Atalay M, Mussalo H, Lankinen M, Oresic M, Lehto S, Uusitupa M, De Mello VDF, Schwab US, Pulkkinen L, Kolehmainen M, Lankinen M, Uusitupa M. 2009. European journal of nutrition. 48: 447-455 A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä

Dietary fatty acids and cardiovascular disease: an epidemiological approach

Erkkilä A, de Mello VDF, Risérus U, Laaksonen DE. 2008. Progress in lipid research. 47: 172-187 A2 Katsausartikkeli tieteellisessä aikakauslehdessä

Downregulation of genes involved in NFkappaB activation in peripheral blood mononuclear cells after weight loss is associated with the improvement of insulin sensitivity in individuals with the metabolic syndrome: the GENOBIN study

De Mello V, Kolehmainen M, Pulkkinen L, Schwab U, Mager U, Laaksonen DE, Niskanen L, Gylling H, Atalay M, Rauramaa R, Uusitupa M, De Mello V, Kolehmainen M, Pulkkinen L, Schwab U, Mager U, Gylling H, Uusitupa M. 2008. Diabetologia. 51: 2060-2067 A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä

Effect of weight loss on cytokine messenger RNA expression in peripheral blood mononuclear cells of obese subjects with the metabolic syndrome

de Mello VDF, Kolehmainen M, Schwab U, Mager U, Laaksonen DE, Pulkkinen L, Niskanen L, Gylling H, Atalay M, Rauramaa R, Uusitupa M, Ferreira de Mello V, Kolehmainen M, Schwab U, Mager U, Pulkkinen L, Gylling H, Uusitupa M. 2008. Metabolism: clinical and experimental. 57: 192-199 A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä

Effects of fatty and lean fish intake on blood pressure in subjects with coronary heart disease using multiple medications

Erkkilä AT, Schwab US, De Mello VDF, Lappalainen T, Mussalo H, Lehto S, Kemi V, Lamberg-Allardt C, Uusitupa MIJ. 2008. European journal of nutrition. 47: 319-328 A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä

Expression of ghrelin gene in peripheral blood mononuclear cells and plasma ghrelin concentrations in patients with metabolic syndrome

Mager U, Kolehmainen M, de Mello VDF, Schwab U, Laaksonen DE, Rauramaa R, Gylling G, Atalay M, Pulkkinen L, Uusitupa M, Mager U, Kolehmainen M, Ferreira, Schwab U, Gylling H, Pulkkinen L, Uusitupa M. 2008. European journal of endocrinology. 158: 499-510 A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä

Tarkenna hakuasi

Nutrigenomics and molecular nutrition

Johtajat

Yhteistyö

Johtajat

Cost-Effectiveness of Passion Fruit Albedo versus Turmeric in the Glycemic and Lipaemic Control of People with Type 2 Diabetes: Randomized Clinical Trial

Intake of Camelina Sativa Oil and Fatty Fish Alter the Plasma Lipid Mediator Profile in Subjects with Impaired Glucose Metabolism - A Randomized Controlled Trial

Serum aromatic and branched-chain amino acids associated with NASH demonstrate divergent associations with serum lipids

An Isocaloric Nordic Diet Modulates RELA and TNFRSF1A Gene Expression in Peripheral Blood Mononuclear Cells in Individuals with Metabolic Syndrome-A SYSDIET Sub-Study

Camelina sativa Oil, Fatty Fish, and Lean Fish Do Not Markedly Affect Urinary Prostanoids in Subjects with Impaired Glucose Metabolism

Healthy Nordic Diet Modulates the Expression of Genes Related to Mitochondrial Function and Immune Response in Peripheral Blood Mononuclear Cells from Subjects with the Metabolic Syndrome - A SYSDIET Sub-Study

Liver DNA methylation of FADS2 associates with FADS2 genotypex

The effect of different sources of fish and camelina sativa oil on immune cell and adipose tissue mRNA expression in subjects with abnormal fasting glucose metabolism: a randomized controlled trial

Total liver phosphatidylcholine content associates with non-alcoholic steatohepatitis and glycine N-methyltransferase expression

Associations of serum indolepropionic acid, a gut microbiota metabolite, with type 2 diabetes and low-grade inflammation in high-risk individuals

Camelina Sativa Oil, but not Fatty Fish or Lean Fish Improved Serum Lipid Profile in Subjects with Impaired Glucose Metabolism - a Randomized Controlled Trial

Intake of Fatty Fish Alters the Size and the Concentration of Lipid Components of HDL Particles and Camelina Sativa Oil Decreases IDL Particle Concentration in Subjects with Impaired Glucose Metabolism

Serum Adiponectin/Ferritin Ratio in Relation to the Risk of Type 2 diabetes and Insulin Sensitivity

Serum, liver and bile sitosterol and sitostanol in obese patients with and without NAFLD

Sex Differences in the Methylome and Transcriptome of the Human Liver and Circulating HDL-Cholesterol Levels

The effect of camelina sativa oil and fish intakes on fatty acid compositions of blood lipid fractions

Diabetes medication associates with DNA methylation of metformin transporter genes in the human liver

Fasting serum hippuric acid is elevated after bilberry (Vaccinium myrtillus) consumption and associates with improvement of fasting glucose levels and insulin secretion in persons at high risk of developing type 2 diabetes

Indolepropionic acid and novel lipid metabolites are associated with a lower risk of type 2 diabetes in the Finnish Diabetes Prevention Study

DNA methylation of loci within ABCG1 and PHOSPHO1 in blood DNA is associated with future type 2 diabetes risk

Effect of a 2-y dietary and physical activity intervention on plasma fatty acid composition and estimated desaturase and elongase activities in children: the Physical Activity and Nutrition in Children Study

Effects of a healthy Nordic diet on gene expression changes in peripheral blood mononuclear cells in response to an oral glucose tolerance test in subjects with metabolic syndrome: a SYSDIET sub-study

Epigenetic alterations in blood mirror age-associated DNA methylation and gene expression changes in human liver

Reduction in cardiometabolic risk factors by a multifunctional diet is mediated via several branches of metabolism as evidenced by non-targeted metabolite profiling approach

Cross-sectional associations of plasma fatty acid composition and estimated desaturase and elongase activities with cardiometabolic risk in Finnish children - The PANIC study

Epigenetic alterations in human liver from subjects with type 2 diabetes in parallel with reduced folate levels

Gene-diet interaction of a common FADS1 variant with marine polyunsaturated fatty acids for fatty acid composition in plasma and erythrocytes among men

Glucose Metabolism Effects of Vitamin D in Prediabetes: the VitDmet Randomized Placebo-Controlled Supplementation Study

Longitudinal associations of serum fatty acid composition with type 2 diabetes risk and markers of insulin secretion and sensitivity in the Finnish Diabetes Prevention Study

Markers of cholesterol metabolism as biomarkers in predicting diabetes in the Finnish Diabetes Prevention Study

Relevance of Vitamin D Receptor Target Genes for Monitoring the Vitamin D Responsiveness of Primary Human Cells

Associations of erythrocyte membrane fatty acids with the concentrations of C-reactive protein, interleukin 1 receptor antagonist and adiponectin in1373 men

Changes in vitamin D target gene expression in adipose tissue monitor the vitamin D response of human individuals

Cross-Sectional Associations of Food Consumption with Plasma Fatty Acid Composition and Estimated Desaturase Activities in Finnish Children

DNA methylation in obesity and type 2 diabetes

Dissecting high from low responders in a vitamin D3 intervention study

Healthy Nordic diet downregulates the expression of genes involved in inflammation in subcutaneous adipose tissue in individuals with features of the metabolic syndrome

Nontargeted metabolite profiling discriminates diet-specific biomarkers for consumption of whole grains, fatty fish, and bilberries in a randomized controlled trial

Primary vitamin D receptor target genes as biomarkers for the vitamin D3 status in the hematopoietic system

Effect of fatty and lean fish intake on lipoprotein subclasses in subjects with coronary heart disease: A controlled trial

Primary vitamin D target genes allow a categorization of possible benefits of vitamin D3 supplementation

Gene expression of peripheral blood mononuclear cells as a tool in dietary intervention studies: What do we know so far?

Insulin secretion and its determinants in the progression of impaired glucose tolerance to type 2 diabetes in impaired glucose-tolerant individuals: the finnish diabetes prevention study

Leukocyte Telomere Lenght in the Finnish Diabetes Prevention Study

A diet high in fatty fish, bilberries and wholegrain products improves markers of endothelial function and inflammation in individuals with impaired glucose metabolism in a randomised controlled trial: The Sysdimet study

High dietary glycemic index and low fiber content are associated with metabolic syndrome in patients with type 2 diabetes

Gene Expression of FTO in Human Subcutaneous Adipose Tissue, Peripheral Blood Mononuclear Cells and Adipocyte Cell Line.

Fibras na dieta: tendencias atuais e benefícios à saúde na síndrome metabólica e no diabetes melito tipo 2. Dietary fibers: current trents and health benefits in the metabolic syndrome and type 2 diabetes

Link between plasma ceramides, inflammation and insulin resistance: association with serum IL-6 concentration in patients with coronary heart disease

Papel do indice glimemico e da carga glicemica na prevencao e no controle metabolico de pacientes com daibetes melito tipo 2.Glycemic index and glycemic load in the prevention and treatment of type 2 diabetes mellitus

The effect of fatty or lean fish intake on inflammatory gene expression in peripheral blood mononuclear cells of patients with coronary heart disease

Dietary fatty acids and cardiovascular disease: an epidemiological approach

Downregulation of genes involved in NFkappaB activation in peripheral blood mononuclear cells after weight loss is associated with the improvement of insulin sensitivity in individuals with the metabolic syndrome: the GENOBIN study

Effect of weight loss on cytokine messenger RNA expression in peripheral blood mononuclear cells of obese subjects with the metabolic syndrome

Effects of fatty and lean fish intake on blood pressure in subjects with coronary heart disease using multiple medications

Expression of ghrelin gene in peripheral blood mononuclear cells and plasma ghrelin concentrations in patients with metabolic syndrome