GenomMed

Julkaisut

• Biomarkers for posttraumatic epilepsy Pitkänen, Asla; Paananen, Tomi; Kyyriäinen, Jenni; Das Gupta, Shalini; Heiskanen, Mette; Vuokila, Niina; Bañuelos-Cabrera, Ivette; Lapinlampi, Niina; Kajevu, Natallie; Andrade, Pedro; Ciszek, Robert; Lara-Valderrábano, Leonardo; Ekolle Ndode-Ekane, Xavier; Puhakka, Noora. 2021. Biomarkers for posttraumatic epilepsy Epilepsy and behavior 121 Part B: 107080. 2021
• BV-2 Microglial Cells Overexpressing C9orf72 Hexanucleotide Repeat Expansion Produce DPR Proteins and Show Normal Functionality but No RNA Foci Rostalski, Hannah; Hietanen, Tomi; Leskelä, Stina; Behánová, Andrea; Abdollahzadeh, Ali; Wittrahm, Rebekka; Mäkinen, Petra; Huber, Nadine; Hoffmann, Dorit; Solje, Eino; Remes, Anne M; Natunen, Teemu; Takalo, Mari; Tohka, Jussi; Hiltunen, Mikko; Haapasalo, Annakaisa. 2020. BV-2 Microglial Cells Overexpressing C9orf72 Hexanucleotide Repeat Expansion Produce DPR Proteins and Show Normal Functionality but No RNA Foci Frontiers in neurology 11: 550140. 2020
• The Alzheimer's disease-associated protective Plcγ2-P522R variant promotes immune functions Takalo, Mari; Wittrahm, Rebekka; Wefers, Benedikt; Parhizkar, Samira; Jokivarsi, Kimmo; Kuulasmaa, Teemu; Mäkinen, Petra; Martiskainen, Henna; Wurst, Wolfgang; Xiang, Xianyuan; Marttinen, Mikael; Poutiainen, Pekka; Haapasalo, Annakaisa; Hiltunen, Mikko; Haass, Christian. 2020. The Alzheimer's disease-associated protective Plcγ2-P522R variant promotes immune functions Molecular neurodegeneration 15 1: 52. 2020
• Altered Insulin Signaling in Alzheimer's Disease Brain - Special Emphasis on PI3K-Akt Pathway Gabbouj, Sami; Ryhanen, Simo; Marttinen, Mikael; Wittrahm, Rebekka; Takalo, Mari; Kemppainen, Susanna; Martiskainen, Henna; Tanila, Heikki; Haapasalo, Annakaisa; Hiltunen, Mikko; Natunen, Teemu. 2019. Altered Insulin Signaling in Alzheimer's Disease Brain - Special Emphasis on PI3K-Akt Pathway Frontiers in neuroscience 13: 629. 2019
• Astrocytes and Microglia as Potential Contributors to the Pathogenesis of C9orf72 Repeat Expansion-Associated FTLD and ALS Rostalski, Hannah; Leskelä, Stina; Huber, Nadine; Katisko, Kasper; Cajanus, Antti; Solje, Eino; Marttinen, Mikael; Natunen, Teemu; Remes, Anne M; Hiltunen, Mikko; Haapasalo, Annakaisa. 2019. Astrocytes and Microglia as Potential Contributors to the Pathogenesis of C9orf72 Repeat Expansion-Associated FTLD and ALS Frontiers in neuroscience 13: 486. 2019
• Automatic Rodent Brain MRI Lesion Segmentation with Fully Convolutional Networks Automatic Rodent Brain MRI Lesion Segmentation with Fully Convolutional Networks. Valverde, JM; Shatillo, A; De Feo, R; Gröhn, O; Sierra, A; Tohka, J / Machine Learning in Medical Imaging. MLMI 2019. 2019. 2019
• PSEN1ΔE9, APPswe, and APOE4 Confer Disparate Phenotypes in Human iPSC-Derived Microglia Konttinen, H; Cabral-da-Silva, MEC; Ohtonen, S; Wojciechowski, S; Shakirzyanova, A; Caligola, S; Giugno, R; Ishchenko, Y; Hernández, D; Fazaludeen, MF; Eamen, S; Budia, MG; Fagerlund, I; Scoyni, F; Korhonen, P; Huber, N; Haapasalo, A; Hewitt, AW; Vickers, J; Smith, GC; et al.. 2019. PSEN1ΔE9, APPswe, and APOE4 Confer Disparate Phenotypes in Human iPSC-Derived Microglia Stem cell reports 13 4: 669-683. 2019
• Predicting Intelligence Based on Cortical WM/GM Contrast, Cortical Thickness and Volumetry Predicting Intelligence Based on Cortical WM/GM Contrast, Cortical Thickness and Volumetry. Valverde, JM; Imani, V; Lewis, JD; Tohka, J / Adolescent Brain Cognitive Development Neurocognitive Prediction. ABCD-NP 2019. 2019. 2019
• Extracellular Prolyl Oligopeptidase Derived from Activated Microglia is a Potential Neuroprotection Target. Natunen, Teemu A; Gynther, Mikko; Rostalski, Hannah; Jaako, Külli; Jalkanen, Aaro J. 2018. Extracellular Prolyl Oligopeptidase Derived from Activated Microglia is a Potential Neuroprotection Target. Basic and clinical pharmacology and toxicology 2019; 124 1: 40-49. 2018
• Intranasal insulin activates Akt2 signaling pathway in the hippocampus of wild-type but not in APP/PS1 Alzheimer model mice Gabbouj, S; Natunen, T; Koivisto, H; Jokivarsi, K; Takalo, M; Marttinen, M; Wittrahm, R; Kemppainen, S; Naderi, R; Posado-Fernández, A; Ryhänen, S; Mäkinen, P; Paldanius, KMA; Doria, G; Poutiainen, P; Flores, O; Haapasalo, A; Tanila, H; Hiltunen, M. 2018. Intranasal insulin activates Akt2 signaling pathway in the hippocampus of wild-type but not in APP/PS1 Alzheimer model mice NEUROBIOLOGY OF AGING 2019; 75: 98-108. 2018
• Molecular Mechanisms of Synaptotoxicity and Neuroinflammation in Alzheimer's Disease Marttinen, Mikael; Takalo, Mari; Natunen, Teemu; Wittrahm, Rebekka; Gabbouj, Sami; Kemppainen, Susanna; Leinonen, Ville; Tanila, Heikki; Haapasalo, Annakaisa; Hiltunen, Mikko. 2018. Molecular Mechanisms of Synaptotoxicity and Neuroinflammation in Alzheimer's Disease Frontiers in neurology 12: 963. 2018
• Nuclear factor E2-related factor 2 deficiency impairs atherosclerotic lesion development but promotes features of plaque instability in hypercholesterolemic mice Ruotsalainen, Anna-Kaisa; Lappalainen, Jari P; Heiskanen, Emmi; Merentie, Mari; Näpänkangas, Juha; Lottonen-Raikaslehto, Line; Kansanen, Emilia; Adinolfi, Simone; Kaarniranta, Kai; Ylä-Herttuala, Seppo; Jauhiainen, Matti; Pirinen, Eija; Levonen, Anna-Liisa. 2018. Nuclear factor E2-related factor 2 deficiency impairs atherosclerotic lesion development but promotes features of plaque instability in hypercholesterolemic mice CARDIOVASCULAR RESEARCH 2019; 115 1: 243-254. 2018
• Regulation of stress signaling pathways by nitro-fatty acids Deen, Ashik Jawahar; Sihvola, Virve; Härkönen, Jouni; Patinen, Tommi; Adinolfi, Simone; Levonen, Anna-Liisa. 2018. Regulation of stress signaling pathways by nitro-fatty acids Nitric oxide 78: 170-175. 2018