Neuroinflammation research group

01.06.2015 -

Tutkimusryhmä

Tutustu tutkimusryhmäämme tarkemmin englanninkieliseltä sivulta.

Tutkimusryhmän sivut

Avainsanat

abeta aivohalvaus Alzheimerin tauti astrosyytti ei-koodaava RNA eksosomi elävien solujen kuvantaminen JPND monifotonikuvaus neuro-immuuni vuorovaikutus neuroinflammaatio puhdistuma sekvensointi synapsi

Ajanjakso

01.06.2015 -

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Ryhmän jäsenet - UEF

Muut ryhmän jäsenet

Iveta Stanova iveta.stanova@uef.fi
Landreth Gary
Brites Dora
White Anthony
Pebay Alice
Lezanne Ooi
Beth Stevens
Ville Leinonen
Evan Macosko
Olga Neustroeva olga.neustroeva@uef.fi

Julkaisut

Changes in nuclear and cytoplasmic microRNA distribution in response to hypoxic stress Turunen, TA; Roberts, TC; Laitinen, P; Väänänen, MA; Korhonen, P; Malm, T; Ylä-Herttuala, S; Turunen, M. 2019. Changes in nuclear and cytoplasmic microRNA distribution in response to hypoxic stress Scientific reports 9: 10332. 2019
Loss of Cln5 leads to altered Gad1 expression and deficits in interneuron development in mice Singh, Y; Leinonen, H; Fazaludeen, F; Jaronen, M; Guest, D; Buckley, N; Byts, N; Oksa, P; Jalkanen, K; Iqbal, I; Huuskonen, M; Savchenko, E; Keksa-Goldsteine, V; Chew, S; Myllyharju, J; Tanila, H; Ooi, L; Koistinaho, J; Kanninen, KM; Malm, T. 2019. Loss of Cln5 leads to altered Gad1 expression and deficits in interneuron development in mice Human molecular genetics 28 11: 3309-3322. 2019
PSEN1ΔE9, APPswe, and APOE4 Confer Disparate Phenotypes in Human iPSC-Derived Microglia Konttinen, H; Cabral-da-Silva, MEC; Ohtonen, S; Wojciechowski, S; Shakirzyanova, A; Caligola, S; Giugno, R; Ishchenko, Y; Hernández, D; Fazaludeen, MF; Eamen, S; Budia, MG; Fagerlund, I; Scoyni, F; Korhonen, P; Huber, N; Haapasalo, A; Hewitt, AW; Vickers, J; Smith, GC; et al.. 2019. PSEN1ΔE9, APPswe, and APOE4 Confer Disparate Phenotypes in Human iPSC-Derived Microglia Stem cell reports 13 4: 669-683. 2019
The viral protein corona directs viral pathogenesis and amyloid aggregation Ezzat, K; Pernemalm, M; Pålsson, S; Roberts, TC; Järver, P; Dondalska, A; Bestas, B; Sobkowiak, MJ; Levänen, B; Sköld, M; Thompson, EA; Saher, O; Kari, OK; Lajunen, T; Sverremark Ekström, E; Nilsson, C; Ishchenko, Y; Malm, T; Wood, MJA; Power, UF; et al.. 2019. The viral protein corona directs viral pathogenesis and amyloid aggregation Nature communications 10 1: 2331. 2019
HX600, a synthetic agonist for RXR-Nurr1 heterodimer complex, prevents ischemia-induced neuronal damage Loppi, S; Kolosowska, N; Kärkkäinen, O; Korhonen, P; Huuskonen, M; Grubman, A; Dhungana, H; Wojciechowski, S; Pomeshchik, Y; Giordano, M; Kagechika, H; White, A; Auriola, S; Koistinaho, J; Landreth, G; Hanhineva, K; Kanninen, K; Malm, T. 2018. HX600, a synthetic agonist for RXR-Nurr1 heterodimer complex, prevents ischemia-induced neuronal damage Brain, behavior, and immunity 73: 670-681. 2018
PPARß/DELTA-agonist GW0742 ameliorates dysfunction in fatty acid oxidation in PSEN1deltaE9 astrocytes Konttinen, H; Gureviciene, I; Oksanen, M; Grubman, A; Loppi, S; Huuskonen, MT; Korhonen, P; Lampinen, R; Keuters, M; Belaya, I; Tanila, H; Kanninen, KM; Goldsteins, G; Landreth, G; Koistinaho, J; Malm, T. 2018. PPARß/DELTA-agonist GW0742 ameliorates dysfunction in fatty acid oxidation in PSEN1deltaE9 astrocytes GLIA 2019; 67 1: 146-159. 2018
Sulfosuccinimidyl oleate sodium is neuroprotective and alleviates stroke-induced neuroinflammation Dhungana H, Huuskonen MT, Jaronen M, Lemarchant S, Ali H, Keksa-Goldsteine V, Goldsteins G, Kanninen KM, Koistinaho J, Malm T. 2017. Sulfosuccinimidyl oleate sodium is neuroprotective and alleviates stroke-induced neuroinflammation. JOURNAL OF NEUROINFLAMMATION [HTTP://WWW.JNEUROINFLAMMATION.COM/] 14 11: 237. 2017
Activation of the nuclear receptor PPARdelta is neuroprotective in a transgenic mouse model of Alzheimer's disease through inhibition of inflammation Malm Tarja, Mariani Monica, Donovan Lauren J, Neilson Lee, Landreth Gary E. 2015. Activation of the nuclear receptor PPARdelta is neuroprotective in a transgenic mouse model of Alzheimer's disease through inhibition of inflammation. JOURNAL OF NEUROINFLAMMATION [HTTP://WWW.JNEUROINFLAMMATION.COM/] 12 7: 15 p. 2015
Immunomodulation by interleukin-33 is protective in stroke through modulation of inflammation Korhonen Paula, Kanninen Katja M, Lehtonen Sarka, Lemarchant Sighild, Puttonen Katja A, Oksanen Minna, Dhungana Hiramani, Loppi Sanna, Pollari Eveliina, Wojciechowski Sara, Kidin Iurii, Garcia-Berrocoso Teresa, Giralt Dolors, Montaner Joan, Koistinaho Jan I, Malm Tarja. 2015. Immunomodulation by interleukin-33 is protective in stroke through modulation of inflammation Brain, behavior, and immunity 49: 322-336. 2015
Transplanted human iPSC-derived neural progenitor cells do not promote functional recovery of pharmacologically immunosuppressed mice with contusion spinal cord injury Pomeshchik Y, Puttonen KA, Kidin I, Ruponen M, Lehtonen S, Malm T, Akesson E, Hovatta O, Koistinaho J. 2014. Transplanted human iPSC-derived neural progenitor cells do not promote functional recovery of pharmacologically immunosuppressed mice with contusion spinal cord injury. Cell Transplantation 2014 Sep 8. [Epub ahead of print]: - -. 2014

Neuroinflammation research group

Avainsanat

Ajanjakso

Ryhmän jäsenet - UEF

Johtaja(t)

Vanhemmat tutkijat

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Väitöskirjatutkijat

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