Einari Niskanen - UEFConnect

Tarkenna hakuasi

Tutkimusryhmät

Projektit

BalticSeaBioMed 15.05.2023 - 15.05.2099

Avainsanat

bioinformatiikka genomiikka glukokortikoidi glukokortikoidireseptori GWAS haittavaikutukset koregulaattorit kortisoli solustressi stressihormonit SUMO transkription repressio transkription säätely transkriptiotekijät tulehdusvaste

Julkaisut

24/24 kappaletta

SUMOylation inhibition potentiates the glucocorticoid receptor to program growth arrest of acute lymphoblastic leukemia cells
Valima, Emma; Varis, Vera; Bureiko, Kseniia; Lempiäinen, Joanna K.; Schroderus, Anna-Mari; Oksa, Laura; Lohi, Olli; Kinnunen, Tuure; Varjosalo, Markku; Niskanen, Einari A; Paakinaho, Ville; Palvimo, Jorma J. 2025. Oncogene. [Published: 14 February 2025]: 1-13 A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä
Central role of SUMOylation in the regulation of chromatin interactions and transcriptional outputs of the androgen receptor in prostate cancer cells
Launonen, Kaisa-Mari; Varis, Vera; Aaltonen, Niina; Niskanen, Einari A; Varjosalo, Markku; Paakinaho, Ville; Palvimo, Jorma J. 2024. Nucleic acids research. 52: 9519-9535 A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä
Secreted factors from M1 macrophages drive prostate cancer stem cell plasticity by upregulating NANOG, SOX2, and CD44 through NFκB-signaling
Kainulainen, Kirsi; Niskanen, Einari A; Kinnunen, Johanna; Mäki-Mantila, Kaisa; Hartikainen, Kiia; Paakinaho, Ville; Malinen, Marjo; Ketola, Kirsi; Pasonen-Seppänen, Sanna. 2024. Oncoimmunology. 13: . 2393442 A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä
Steroidireseptorien säätely
Paakinaho, Ville; Niskanen, Einari A. 2024. Duodecim. 140: 759-767 A2 Katsausartikkeli tieteellisessä aikakauslehdessä
Chromatin accessibility and pioneer factor FOXA1 restrict glucocorticoid receptor action in prostate cancer
Helminen, Laura; Huttunen, Jasmin; Tulonen, Melina; Aaltonen, Niina; Niskanen, Einari A; Palvimo, Jorma J; Paakinaho, Ville. 2023. Nucleic acids research. 2024; 52: 625-642 A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä
Complementary analysis of proteome‐wide proteomics reveals changes in RNA binding protein‐profiles during prostate cancer progression
Aikio, Erika; Koivukoski, Sonja; Kallio, Elina; Sadeesh, Nithin; Niskanen, Einari A; Latonen, Leena. 2023. Cancer reports. 6: A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä
Genetic variation is a key determinant of chromatin accessibility and drives differences in the regulatory landscape of C57BL/6J and 129S1/SvImJ mice
Mononen, Juho; Taipale, Mari; Malinen, Marjo; Velidendla, Bharadwaja; Niskanen, Einari; Levonen, Anna-Liisa; Ruotsalainen, Anna-Kaisa; Heikkinen, Sami. 2023. Nucleic acids research. 2024; 52: 2904-2923 A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä
International Online Team-Based Learning in Higher Education of Biomedicine - Evaluation by Learning Analytics
Mairinoja, Laura; López-Pernas, Sonsoles; Elmoazen, Ramy; Niskanen, Einari A.; Kuningas, Tiina; Wärri, Anni; Saqr, Mohammed; Strauss, Leena. Teoksessa: Elmoazen, Ramy; López-Pernas, Sonsoles; Misiejuk, Kamila; Khalil, Mohammad; Wasson, Barbara; Saqr, Mohammed(toim.) , 2023. Proceedings of the Technology-Enhanced Learning in Laboratories Workshop (TELL 2023). s. 49-60. A4 Artikkeli konferenssijulkaisussa
Parvovirus nonstructural protein 2 interacts with chromatin-regulating cellular proteins
Mattola, Salla; Salokas, Kari; Aho, Vesa; Mäntylä, Elina; Salminen, Sami; Hakanen, Satu; Niskanen, Einari A.; Svirskaite, Julija; Ihalainen, Teemu O.; Airenne, Kari J.; Kaikkonen-Määttä, Minna; Parrish, Colin R.; Varjosalo, Markku; Vihinen-Ranta, Maija. 2022. PLoS pathogens. 18: A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä
BCOR modulates transcriptional activity of a subset of glucocorticoid receptor target genes involved in cell growth and mobility
Manjur, ABMK; Lempiäinen, JK; Malinen, M; Varjosalo, M; Palvimo, JJ; Niskanen, EA. 2021. Journal of steroid biochemistry and molecular biology
Chromatin-directed proteomics-identified network of endogenous androgen receptor in prostate cancer cells
Launonen, Kaisa-Mari; Paakinaho, Ville; Sigismondo, Gianluca; Malinen, Marjo; Sironen, Reijo; Hartikainen, Jaana M; Laakso, Hanna; Visakorpi, Tapio; Krijgsveld, Jeroen; Niskanen, Einari A; Palvimo, Jorma J. 2021. Oncogene
SUMOylation regulates the protein network and chromatin accessibility at glucocorticoid receptor-binding sites
Paakinaho, Ville; Lempiäinen, Joanna K; Sigismondo, Gianluca; Niskanen, Einari A; Malinen, Marjo; Jääskeläinen, Tiina; Varjosalo, Markku; Krijgsveld, Jeroen; Palvimo, Jorma J. 2021. Nucleic acids research
Stress-induced nuclear condensation of NELF drives transcriptional downregulation
Rawat, Prashant; Boehning, Marc; Hummel, Barbara; Aprile-Garcia, Fernando; Pandit, Anwit S; Eisenhardt, Nathalie; Khavaran, Ashkan; Niskanen, Einari; Vos, Seychelle M; Palvimo, Jorma J; Pichler, Andrea; Cramer, Patrick; Sawarkar, Ritwick. 2021. Molecular cell
BCOR-coupled H2A monoubiquitination represses a subset of androgen receptor target genes regulating prostate cancer proliferation
Lempiäinen, JK; Manjur, ABMK; Malinen, M; Ketola, K; Niskanen, EA; Palvimo, JJ. 2020. Oncogene
Histonien muokkaukset ja geenien säätely
Sutinen, Siiri; Niskanen, Einari. 2020. Solubiologi
IRF2BP2 Modulates the Crosstalk between Glucocorticoid and TNF Signaling
Kaiser Manjur, ABM; Lempiäinen, Joanna K; Malinen, Marjo; Palvimo, Jorma J; Niskanen, Einari A. 2019. Journal of steroid biochemistry and molecular biology
Lack of androgen receptor SUMOylation results in male infertility due to epididymal dysfunction
Zhang, Fu-Ping; Malinen, Marjo; Mehmood, Arfa; Lehtiniemi, Tiina; Jääskeläinen, Tiina; Niskanen, Einari A; Korhonen, Hanna; Laiho, Asta; Elo, Laura L; Ohlsson, Claes; Kotaja, Noora; Poutanen, Matti; Sipilä, Petra; Palvimo, Jorma J. 2019. Nature communications
Agonist-specific Protein Interactomes of Glucocorticoid and Androgen Receptor as Revealed by Proximity Mapping
Lempiäinen Joanna K, Niskanen Einari A, Vuoti Kaisa-Mari, Lampinen Riikka E, Göös Helka, Varjosalo Markku, Palvimo Jorma J. 2017. Molecular and cellular proteomics
Chromatin SUMOylation in heat stress : to protect, pause and organise?
Niskanen Einari A, Palvimo Jorma J. 2017. Bioessays
Crosstalk between androgen and pro-inflammatory signaling remodels androgen receptor and NF-kB cistrome to reprogram the prostate cancer cell transcriptome
Malinen Marjo, Niskanen Einari A, Kaikkonen Minna U, Palvimo Jorma J. 2016. Nucleic acids research
Global analysis of transcription in castration-resistant prostate cancer cells uncovers active enhancers and direct androgen receptor targets
Toropainen Sari, Niskanen Einari A, Malinen Marjo, Sutinen Päivi, Kaikkonen Minna U, Palvimo Jorma J. 2016. Scientific reports
Promoter-Targeted Histone Acetylation of Chromatinized Parvoviral Genome Is Essential for the Progress of Infection
Mäntylä E, Salokas K, Oittinen M, Aho V, Mäntysaari P, Palmujoki L, Kalliolinna O, Ihalainen TO, Niskanen EA, Timonen J, Viiri K, Vihinen-Ranta M. 2016. Journal of virology
Global SUMOylation on active chromatin is an acute heat stress response restricting transcription
Niskanen Einari A, Malinen Marjo, Sutinen Päivi, Toropainen Sari, Paakinaho Ville, Vihervaara Anniina, Joutsen Jenny, Kaikkonen Minna U, Sistonen Lea, Palvimo Jorma J. 2015. Genome biology
Reorganization of nuclear pore complexes and the lamina in late-stage parvovirus infection
Mäntylä Elina, Niskanen Einari A, Ihalainen Teemu O, Vihinen-Ranta Maija. 2015. Journal of virology

Tarkenna hakuasi

Einari A. Niskanen

Tutkimusryhmät

Projektit

Avainsanat

SUMOylation inhibition potentiates the glucocorticoid receptor to program growth arrest of acute lymphoblastic leukemia cells

Central role of SUMOylation in the regulation of chromatin interactions and transcriptional outputs of the androgen receptor in prostate cancer cells

Secreted factors from M1 macrophages drive prostate cancer stem cell plasticity by upregulating NANOG, SOX2, and CD44 through NFκB-signaling

Steroidireseptorien säätely

Chromatin accessibility and pioneer factor FOXA1 restrict glucocorticoid receptor action in prostate cancer

Complementary analysis of proteome‐wide proteomics reveals changes in RNA binding protein‐profiles during prostate cancer progression

Genetic variation is a key determinant of chromatin accessibility and drives differences in the regulatory landscape of C57BL/6J and 129S1/SvImJ mice

International Online Team-Based Learning in Higher Education of Biomedicine - Evaluation by Learning Analytics

Parvovirus nonstructural protein 2 interacts with chromatin-regulating cellular proteins

BCOR modulates transcriptional activity of a subset of glucocorticoid receptor target genes involved in cell growth and mobility

Chromatin-directed proteomics-identified network of endogenous androgen receptor in prostate cancer cells

SUMOylation regulates the protein network and chromatin accessibility at glucocorticoid receptor-binding sites

Stress-induced nuclear condensation of NELF drives transcriptional downregulation

BCOR-coupled H2A monoubiquitination represses a subset of androgen receptor target genes regulating prostate cancer proliferation

Histonien muokkaukset ja geenien säätely

IRF2BP2 Modulates the Crosstalk between Glucocorticoid and TNF Signaling

Lack of androgen receptor SUMOylation results in male infertility due to epididymal dysfunction

Agonist-specific Protein Interactomes of Glucocorticoid and Androgen Receptor as Revealed by Proximity Mapping

Chromatin SUMOylation in heat stress : to protect, pause and organise?

Crosstalk between androgen and pro-inflammatory signaling remodels androgen receptor and NF-kB cistrome to reprogram the prostate cancer cell transcriptome

Global analysis of transcription in castration-resistant prostate cancer cells uncovers active enhancers and direct androgen receptor targets

Promoter-Targeted Histone Acetylation of Chromatinized Parvoviral Genome Is Essential for the Progress of Infection

Global SUMOylation on active chromatin is an acute heat stress response restricting transcription

Reorganization of nuclear pore complexes and the lamina in late-stage parvovirus infection