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Sanna Oikari

Sanna Oikari

University Lecturer

Institute of Biomedicine, School of Medicine, Faculty of Health Sciences

[email protected] | +358 50 442 3214

Information Publications

Research groups

Molecular mechanisms of tumor-stroma interaction - Pasonen-Seppänen lab 01.01.2021 -
Rilla Lab 01.09.2013 -

Publications

52/52 items

Fast label-free live imaging with FlowVision reveals key principles of cancer cell arrest on endothelial monolayers
Follain, Gautier; Ghimire, Sujan; Pylvänäinen, Joanna W; Vaitkevičiūtė, Monika; Hidalgo-Cenalmor, Iván; Wurzinger, Diana; Guzmán, Camilo; Conway, James R W; Dibus, Michal; Härkönen, Jouni; Oikari, Sanna; Rilla, Kirsi; Salmi, Marko; Ivaska, Johanna; Jacquemet, Guillaume, 2026, Embo journal, [Published: 06 January 2026], 1-41. A1 Journal article (refereed), original research
Assessment of Joint Integrity via Near-Infrared Spectroscopic Estimation of Biomarkers in Synovial Fluid: A Potential Tool for Early Detection of Osteoarthritis
Shahini, Fatemeh; Oikari, Sanna; Sadeesh, Nithin; Nippolainen, Ervin; Brommer, Harold; Töyräs, Juha; Nieminen, Petteri; Afara, Isaac O., 2025, Huang, Zhiwei; Lilge, Lothar D, Progress in Biomedical Optics and Imaging Proceedings of SPIE. A4 Conference proceedings
Non-destructive monitoring of cartilage tissue engineering via near-infrared (NIR) spectroscopic assessment of culture medium
Sadeesh, Nithin; Karunarathna, Harini; Jalali, Abolfazl; Oikari, Sanna; Eskelinen, Antti; Gebraad, Arjen; Nippolainen, Ervin; Miettinen, Susanna; Afara, Isaac O., 2025, Biosensors and bioelectronics, 288, 117809. A1 Journal article (refereed), original research
Hyaluronic Acid and Large Extracellular Vesicles (EVs) in Synovial Fluid and Plasma of Patients With End-Stage Arthritis: Positive Association of EVs to Joint Pain
Mustonen, Anne-Mari; Capra, Janne; Oikari, Sanna; Säisänen, Laura; Karttunen, Lauri; Julkunen, Petro; Lehenkari, Petri; Joukainen, Antti; Jaroma, Antti; Paakkonen, Tommi; Kääriäinen, Tommi; Kröger, Heikki; Nieminen, Petteri, 2024, Cartilage, 16, 2, 169-180. A1 Journal article (refereed), original research
The amount of hyaluronic acid and airway remodelling increase with the severity of inflammation in neutrophilic equine asthma
Höglund, Nina; Rossi, Heini; Javela, Hanna-Maaria; Oikari, Sanna; Nieminen, Petteri; Mustonen, Anne-Mari; Airas, Niina; Kärjä, Vesa; Mykkänen, Anna, 2024, Bmc veterinary research, 20, 1, 273. A1 Journal article (refereed), original research
Counts of hyaluronic acid-containing extracellular vesicles decrease in naturally occurring equine osteoarthritis
Mustonen, Anne-Mari; Lehmonen, Nina; Oikari, Sanna; Capra, Janne; Raekallio, Marja; Mykkänen, Anna; Paakkonen, Tommi; Rilla, Kirsi; Niemelä, Tytti; Nieminen, Petteri, 2022, Scientific reports, 12, 1, 17550. A1 Journal article (refereed), original research
Fatty Acid Fingerprints and Hyaluronic Acid in Extracellular Vesicles from Proliferating Human Fibroblast-like Synoviocytes
Mustonen, Anne-Mari; Paakkonen, Tommi; Matilainen, Johanna; Rilla, Kirsi; Käkelä, Reijo; Malinen, Marjo; Takabe, Piia; Oikari, Sanna; Capra, Janne; Sihvo, Sanna P; Ryökäs, Pauliina; Nieminen, Petteri, 2022, International journal of molecular sciences, 23, 10, 5613. A1 Journal article (refereed), original research
M1 Macrophages Induce Protumor Inflammation in Melanoma Cells through TNFR–NF-κB Signaling
Kainulainen, Kirsi; Takabe, Piia; Heikkinen, Sami; Aaltonen, Niina; de la Motte, Carol; Rauhala, Leena; Durst, Franziska C; Oikari, Sanna; Hukkanen, Taija; Rahunen, Eija; Ikonen, Ella; Hartikainen, Jaana M; Ketola, Kirsi; Pasonen-Seppänen, Sanna, 2022, Journal of investigative dermatology, 1412, 11, 3041-3051.e10. A1 Journal article (refereed), original research
MCF10CA Breast Cancer Cells Utilize Hyaluronan-Coated EV-Rich Trails for Coordinated Migration
Aaltonen, Niina; Kyykallio, Heikki; Tollis, Sylvain; Capra, Janne; Hartikainen, Jaana M.; Matilainen, Johanna; Oikari, Sanna; Rilla, Kirsi, 2022, Frontiers in oncology, 12, 869417. A1 Journal article (refereed), original research
Characterization of hyaluronan-coated extracellular vesicles in synovial fluid of patients with osteoarthritis and rheumatoid
Mustonen, Anne-Mari; Capra, Janne; Rilla, Kirsi; Lehenkari, Petri; Oikari, Sanna; Kääriäinen, Tommi; Joukainen, Antti; Kröger, Heikki; Paakkonen, Tommi; Matilainen, Johanna; Nieminen, Petteri, 2021, Bmc musculoskeletal disorders, 22, 1, 247. A1 Journal article (refereed), original research
The density and length of filopodia associate with the activity of hyaluronan synthesis in tumor cells
Kyykallio, Heikki; Oikari, Sanna; Álvez, María Bueno; Dodd, Carlos José Gallardo; Capra, Janne; Rilla, Kirsi, 2020, Cancers, 12, 7, 1908. A1 Journal article (refereed), original research
The prognostic and predictive role of the neutrophil-to-lymphocyte ratio and the monocyte-to-lymphocyte ratio in early breast cancer, especially in the HER2+ subtype
Tiainen, Satu; Rilla, Kirsi; Hämäläinen, Kirsi; Oikari, Sanna; Auvinen, Päivi, 2020, Breast cancer research and treatment, 2021; 185, 63-72. A1 Journal article (refereed), original research
Activated hyaluronan metabolism in the tumor matrix - Causes and consequences
Tammi, Markku I; Oikari, Sanna; Pasonen-Seppänen, Sanna; Rilla, Kirsi; Auvinen, Päivi; Tammi, Raija H, 2019, Matrix biology, 78-79, 147-164. A2 Review article, Literature review, Systematic review
Analysis of UDP-Sugars from Cultured Cells and Small Tissue Samples
Oikari, Sanna; Tammi, Markku I, 2019, Vigetti, D; Theocharis, A, The Extracellular Matrix, 81-89. A3 Book section, Chapters in research books
CD44s Assembles Hyaluronan Coat on Filopodia and Extracellular Vesicles and Induces Tumorigenicity of MKN74 Gastric Carcinoma Cells
Härkönen, K; Oikari, S; Kyykallio, H; Capra, J; Hakkola, S; Ketola, K; Thanigai Arasu, U; Daaboul, G; Malloy, A; Oliveira, C; Jokelainen, O; Sironen, R; Hartikainen, JM; Rilla, K, 2019, Cells, 8, 3, 276. A1 Journal article (refereed), original research
Effects of mutations in the post-translational modification sites on the trafficking of hyaluronan synthase 2 (HAS2)
Melero-Fernandez de Mera, RM; Arasu, UT; Kärnä, R; Oikari, S; Rilla, K; Vigetti, D; Passi, A; Heldin, P; Tammi, MI; Deen, AJ, 2019, Matrix biology, 80, 85-103. A1 Journal article (refereed), original research
HAS3-induced extracellular vesicles from melanoma cells stimulate IHH mediated c-Myc upregulation via the hedgehog signaling pathway in target cells
Arasu, UT; Deen, AJ; Pasonen-Seppänen, S; Heikkinen, S; Lalowski, M; Kärnä, R; Härkönen, K; Mäkinen, P; Lázaro-Ibáñez, E; Siljander, PR; Oikari, S; Levonen, AL; Rilla, K, 2019, Cellular and molecular life sciences, [Published: 09 December 2019], 1-23. A1 Journal article (refereed), original research
Metformin decreases hyaluronan synthesis by vascular smooth muscle cells
Sainio, A; Takabe, P; Oikari, S; Salomäki-Myftari, H; Koulu, M; Söderström, M; Pasonen-Seppänen, S; Järveläinen, H, 2019, Journal of investigative medicine, 68, 2, 383-391. A1 Journal article (refereed), original research
Peritumoral ADC values in breast cancer: region of interest selection, associations with hyaluronan intensity, and prognostic significance
Kettunen, T; Okuma, H; Auvinen, P; Sudah, M; Tiainen, S; Sutela, A; Masarwah, A; Tammi, M; Tammi, R; Oikari, S; Vanninen, R, 2019, European radiology, 2020; 30, 38-46. A1 Journal article (refereed), original research
Tumor microenvironment and breast cancer survival: combined effects of breast fat, M2 macrophages and hyaluronan create a dismal prognosis
Tiainen, S; Masarwah, A; Oikari, S; Rilla, K; Hämäläinen, K; Sudah, M; Sutela, A; Vanninen, R; Ikonen, J; Tammi, R; Tammi, M; Auvinen, P, 2019, Breast cancer research and treatment, 2020; 179, 565-575. A1 Journal article (refereed), original research
Extracellular ATP activates hyaluronan synthase 2 (HAS2) in epidermal keratinocytes via P2Y2, Ca2+-signaling, and MAPK pathways
Rauhala, L; Jokela, T; Kärnä, R; Bart, G; Takabe, P: Oikari, S; Tammi, MI; Pasonen-Seppänen, S; Tammi, RH, 2018, Biochemical journal, 475, 10, 1755-1772. A1 Journal article (refereed), original research
Hyaluronan metabolism enhanced during epidermal differentiation is suppressed by vitamin C
Hämäläinen, L; Kärkkäinen, E; Takabe, P; Rauhala, L; Bart, G; Kärnä, R; Pasonen-Seppänen, S; Oikari, S; Tammi, MI; Tammi, RH, 2018, British journal of dermatology, 179, 3, 651-661. A1 Journal article (refereed), original research
UDP-sugar accumulation drives hyaluronan synthesis in breast cancer
Oikari, S; Kettunen, T; Tiainen, S; Häyrinen, J; Masarwah, A; Sudah, M; Sutela, A; Vanninen, R; Tammi, M; Auvinen, P, 2018, Matrix biology, 67, 63-74. A1 Journal article (refereed), original research
EMT induced by EGF and wounding activates hyaluronan synthesis machinery and EV shedding in rat primary mesothelial cells
Koistinen Ville, Härkönen Kai, Kärnä Riikka, Arasu Uma Thanigi, OIkari Sanna, Rilla Kirsi, 2017, Matrix biology, 63, 38-54. A1 Journal article (refereed), original research
Human mesenchymal stem cells secrete hyaluronan-coated extracellular vesicles
Arasu UT, Kärnä R, Härkönen K, Oikari S, Koistinen A, Kröger H, Qu C, Lammi MJ, Rilla K, 2017, Matrix biology, 64, 54-68. A1 Journal article (refereed), original research
Hexosamine biosynthesis in keratinocytes: roles of GFAT and GNPDA enzymes in the maintenance of UDP-GlcNAc content and hyaluronan synthesis
Oikari Sanna, Makkonen Katri, Deen Ashik Jawahar, Tyni Ilari, Kärnä Riikka, Tammi Raija H, Tammi Markku I, 2016, Glycobiology, 26, 7, 710-722. A1 Journal article (refereed), original research
High extent of O-GlcNAcylation in breast cancer cells correlates with the levels of HAS enzymes, accumulation of hyaluronan, and poor outcome
Tiainen Satu, Oikari Sanna, Tammi Markku, Rilla Kirsi, Hämäläinen Kirsi, Tammi Raija, Kosma Veli-Matti, Auvinen Päivi, 2016, Breast cancer research and treatment, 160, 2, 237-247. A1 Journal article (refereed), original research
Hyaluronan-positive plasma membrane protrusions exist on mesothelial cells in vivo
Koistinen Ville, Jokela Tiina, Oikari Sanna, Kärnä Riikka, Tammi Markku, Rilla Kirsi, 2016, Histochemistry and cell biology, 145, 5, 531-544. A1 Journal article (refereed), original research
Prognostic contribution of mammographic breast density and HER2 overexpression to the Nottingham Prognostic Index in patients with invasive breast cancer
Masarwah Amro, Auvinen Päivi, Sudah Mazen, Dabravolskaite Vaiva, Arponen Otso, Sutela Anna, Oikari Sanna, Kosma Veli-Matti, Vanninen Ritva, 2016, Bmc cancer, 16, 833. A1 Journal article (refereed), original research
UDP-sugar substrates of HAS3 regulate its O-GlcNAcylation, intracellular traffic, extracellular shedding and correlate with melanoma progression
Deen AJ, Arasu UT, Pasonen-Seppänen S, Hassinen A, Takabe P, Wojciechowski S, Kärnä R, Rilla K, Kellokumpu S, Tammi R, Tammi M, Oikari S, 2016, Cellular and molecular life sciences, 73, 16, 3183-3204. A1 Journal article (refereed), original research
Hyaluronan synthase 1: a mysterious enzyme with unexpected functions
Siiskonen Hanna, Oikari Sanna, Pasonen-Seppänen Sanna, Rilla Kirsi, 2015, Frontiers in immunology, epub. A2 Review article, Literature review, Systematic review
Interleukin-1ß-induced Reduction of CD44 Ser-325 Phosphorylation in Human Epidermal Keratinocytes Promotes CD44 Homomeric Complexes, Binding to Ezrin, and Extended, Monocyte-adhesive Hyaluronan Coats
Jokela Tiina, Oikari Sanna, Takabe Piia, Rilla Kirsi, Kärnä Riikka, Tammi Markku, Tammi Raija, 2015, Journal of biological chemistry, 290, 12379-12393. A1 Journal article (refereed), original research
The reciprocal association between mammographic breast density, hyaluronan synthesis and patient outcome
Masarwah Amro, Tammi Markku, Sudah Mazen, Sutela Anna, Oikari Sanna, Kosma Veli-Matti, Tammi Raija, Vanninen R, Auvinen Päivi, 2015, Breast cancer research and treatment, 153, 3, 625-634. A1 Journal article (refereed), original research
Very low mammographic breast density predicts poorer outcome in patients with invasive breast cancer
Masarwah Amro, Auvinen Päivi, Sudah Mazen, Rautiainen Suvi, Sutela Anna, Pelkonen Outi, Oikari Sanna, Kosma Veli-Matti, Vanninen Ritva, 2015, European radiology, 25, 7, 1875-1882. A1 Journal article (refereed), original research
High numbers of macrophages, especially M2-like (CD163-positive), correlate with hyaluronan accumulation and poor outcome in breast cancer
Tiainen Satu, Tumelius Ritva, Rilla Kirsi, Hämäläinen Kirsi, Tammi Markku, Tammi Raija, Kosma Veli-Matti, Oikari Sanna, Auvinen Päivi, 2014, Histopathology, 2014; 66, 6, 873-883. A1 Journal article (refereed), original research
Rab10-mediated endocytosis of the hyaluronan synthase HAS3 regulates hyaluronan synthesis and cell adhesion to collagen
Deen Ashik Jawahar, Rilla Kirsi, Oikari Sanna, Kärnä Riikka, Bart Genevieve, Häyrinen Jukka, Bathina Avinash Rahul, Ropponen Antti, Makkonen Katri, Tammi Raija H, Tammi Markku I, 2014, Journal of biological chemistry, 289, 12, 8375-89. A1 Journal article (refereed), original research
The dynamic metabolism of hyaluronan regulates the cytosolic concentration of UDP-GlcNAc
Hascall Vincent C, Wang Aimin, Tammi Markku, Oikari Sanna, Tammi Raija, Passi Alberto, Vigetti Davide, Hanson Richard W, Hart Gerald W, 2014, Matrix biology, 35, 14-17. A1 Journal article (refereed), original research
Borate-aided anion exchange high-performance liquid chromatography of uridine diphosphate-sugars in brain, heart, adipose and liver tissues
Oikari S, Venäläinen T, Tammi M, 2013, Journal of chromatography a, 1323, 82-86. A1 Journal article (refereed), original research
Hyaluronan production enhances shedding of plasma membrane-derived microvesicles
Rilla K, Pasonen-Seppänen S, Deen AJ, Koistinen VVT, Wojciechowski S, Oikari S, Kärnä R, Bart G, Törrönen K, Tammi RH, Tammi MI, 2013, Experimental cell research, 319, 13, 2006-2018. A1 Journal article (refereed), original research
Hyaluronan synthase 1 (HAS1) requires higher cellular UDP-GIcNAc concentration than HAS2 and HAS3
Rilla K, Oikari S, Jokela TA, Hyttinen JMT, Kärnä R, Tammi RH, Tammi MI, 2013, Journal of biological chemistry, 288, 8, 5973-5983. A1 Journal article (refereed), original research
Multiple roles of hyaluronan as a target and modifier of the inflammatory response
Oikari S, Jokela TA, Tammi RH, Tammi MI, 2012, Karamanos NK, Extracellular matrix: pathobiology and signaling, 39-65. A3 Book section, Chapters in research books
Cellular Content of UDP-N-acetylhexosamines Controls Hyaluronan Synthase 2 Expression and Correlates with O-Linked N-Acetylglucosamine Modification of Transcription Factors YY1 and SP1
Jokela Tiina A, Makkonen Katri M, Oikari Sanna, Kärnä Riikka, Koli Elina, Hart Gerald W, Tammi Raija H, Tammi Markku I, 2011, Journal of biological chemistry, 289, 38, 33632-33640. A1 Journal article (refereed), original research
Downregulation of PPARs and SREBP by acyl-CoA-binding protein overexpression in transgenic rats
Oikari S, Ahtialansaari T, Heinonen MV, Mauriala T, Auriola S, Kiehne K, Fölsch UR, Jänne J, Alhonen L, Herzig KH, 2008, Pflugers archiv: european journal of physiology, 456, 369-377. A1 Journal article (refereed), original research
Effect of medium- and long-chain fatty acid diets on PPAR and SREBP-1 expression and glucose homeostasis in ACBP-overexpressing transgenic rats
Oikari S, Ahtialansaari T, Huotari A, Kiehne K, Fölsch UR, Wolffram S, Jänne J, Alhonen L, Herzig KH, 2008, Acta physiologica, 194, 57-65. A1 Journal article (refereed), original research
Evaluation of Phenotypic Changes of Acyl-CoA Binding Protein / Diazepam Binding Inhibitor Overexpression in Transgenic Mice and Rats
Oikari S, 2008, Kuopion yliopiston julkaisuja G.- A.I. Virtanen -instituutti. G5 Doctoral dissertation (article)
Diazepam binding inhibitor overexpression in mice causes hydrocephalus, decreases plasticity in excitatory synapses and impairs hippocamus-depend learning
Siiskonen H, Oikari S, Korhonen V-P, Pitkänen A, Voikar V, Kettunen M, Hakumäki J, Wahlfors T, Pussinen R, Penttonen M, Kiehne K, Kaasinen SK, Alhonen L, Jänne J, Herzig K-H, 2007, Molecular and cellular neuroscience, 34, 2, 199-208. A1 Journal article (refereed), original research
Food-induced expression of orexin receptors in rat duodenal mucosa regulates the bicarbonate secretory response to orexin-A
Bengtsson MW, Mäkelä K, Sjöblom M, Uotila S, Åkerman KEO, Herzig K-H, Flemström G, 2007, American journal of physiology : gastrointestinal and liver physiology, 293, G501-G509. A1 Journal article (refereed), original research
Screening for human cationic trypsinogen (PRSS1) and trypsinogen inhibitor gene (SPINK1) mutations in a Finnish family with hereditary pancreatitis
Räty S, Piironen A, Babu M, Pelli H, Sand J, Uotila S, Nordback I, Herzig K-H, 2007, Scandinavian journal of gastroenterology, 42, 8, 1000-1005. A1 Journal article (refereed), original research
Duodenal diazepam-binding protein expression and plasma cholecystokinin after alcoholic pancreatitis
Pelli H, Herzig K-H, Uotila S, Räty S, Laine S, Sand J, Nordback I, 2006, Scandinavian journal of clinical and laboratory investigation, 66, 8, 677-684. A1 Journal article (refereed), original research
VEGF-A, VEGF-D, VEGF receptor-1, VEGF receptor-2, NF-kappaB, and RAGE in atherosclerotic lesions of diabetic Watanabe heritable hyperlipidemic rabbits
Roy H, Bhardwaj S, Babu M, Kokina I, Uotila S, Ahtialansaari T, Laitinen T, Hakumäki J, Laakso M, Herzig K-H, Ylä-Herttuala S, 2006, Faseb journal, 20, 2159-2161. A1 Journal article (refereed), original research
Introduction of histidine residues into avidin subunit interfaces allows pH-dependet regulation of quaternary structure and biotin binding
Nordlund HR, Hytönen VP, Laitinen OH, Uotila STH, Niskanen EA, Savolainen J, Porkka E, Kulomaa MS, 2003, Febs letters, 555, 449-454. A1 Journal article (refereed), original research
The STC-1 cells express functional orexin-A receptors coupled to CCK release
Larsson KP, Åkerman KE, Magga J, Uotila S, Kukkonen JP, Näsman J, Herzig KH, 2003, Biochemical and biophysical research communications, 309, 1, 209-216. A1 Journal article (refereed), original research

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Sanna Oikari

Research groups

Fast label-free live imaging with FlowVision reveals key principles of cancer cell arrest on endothelial monolayers

Assessment of Joint Integrity via Near-Infrared Spectroscopic Estimation of Biomarkers in Synovial Fluid: A Potential Tool for Early Detection of Osteoarthritis

Non-destructive monitoring of cartilage tissue engineering via near-infrared (NIR) spectroscopic assessment of culture medium

Hyaluronic Acid and Large Extracellular Vesicles (EVs) in Synovial Fluid and Plasma of Patients With End-Stage Arthritis: Positive Association of EVs to Joint Pain

The amount of hyaluronic acid and airway remodelling increase with the severity of inflammation in neutrophilic equine asthma

Counts of hyaluronic acid-containing extracellular vesicles decrease in naturally occurring equine osteoarthritis

Fatty Acid Fingerprints and Hyaluronic Acid in Extracellular Vesicles from Proliferating Human Fibroblast-like Synoviocytes

M1 Macrophages Induce Protumor Inflammation in Melanoma Cells through TNFR–NF-κB Signaling

MCF10CA Breast Cancer Cells Utilize Hyaluronan-Coated EV-Rich Trails for Coordinated Migration

Characterization of hyaluronan-coated extracellular vesicles in synovial fluid of patients with osteoarthritis and rheumatoid

The density and length of filopodia associate with the activity of hyaluronan synthesis in tumor cells

The prognostic and predictive role of the neutrophil-to-lymphocyte ratio and the monocyte-to-lymphocyte ratio in early breast cancer, especially in the HER2+ subtype

Activated hyaluronan metabolism in the tumor matrix - Causes and consequences

Analysis of UDP-Sugars from Cultured Cells and Small Tissue Samples

CD44s Assembles Hyaluronan Coat on Filopodia and Extracellular Vesicles and Induces Tumorigenicity of MKN74 Gastric Carcinoma Cells

Effects of mutations in the post-translational modification sites on the trafficking of hyaluronan synthase 2 (HAS2)

HAS3-induced extracellular vesicles from melanoma cells stimulate IHH mediated c-Myc upregulation via the hedgehog signaling pathway in target cells

Metformin decreases hyaluronan synthesis by vascular smooth muscle cells

Peritumoral ADC values in breast cancer: region of interest selection, associations with hyaluronan intensity, and prognostic significance

Tumor microenvironment and breast cancer survival: combined effects of breast fat, M2 macrophages and hyaluronan create a dismal prognosis

Extracellular ATP activates hyaluronan synthase 2 (HAS2) in epidermal keratinocytes via P2Y2, Ca2+-signaling, and MAPK pathways

Hyaluronan metabolism enhanced during epidermal differentiation is suppressed by vitamin C

UDP-sugar accumulation drives hyaluronan synthesis in breast cancer

EMT induced by EGF and wounding activates hyaluronan synthesis machinery and EV shedding in rat primary mesothelial cells

Human mesenchymal stem cells secrete hyaluronan-coated extracellular vesicles

Hexosamine biosynthesis in keratinocytes: roles of GFAT and GNPDA enzymes in the maintenance of UDP-GlcNAc content and hyaluronan synthesis

High extent of O-GlcNAcylation in breast cancer cells correlates with the levels of HAS enzymes, accumulation of hyaluronan, and poor outcome

Hyaluronan-positive plasma membrane protrusions exist on mesothelial cells in vivo

Prognostic contribution of mammographic breast density and HER2 overexpression to the Nottingham Prognostic Index in patients with invasive breast cancer

UDP-sugar substrates of HAS3 regulate its O-GlcNAcylation, intracellular traffic, extracellular shedding and correlate with melanoma progression

Hyaluronan synthase 1: a mysterious enzyme with unexpected functions

Interleukin-1ß-induced Reduction of CD44 Ser-325 Phosphorylation in Human Epidermal Keratinocytes Promotes CD44 Homomeric Complexes, Binding to Ezrin, and Extended, Monocyte-adhesive Hyaluronan Coats

The reciprocal association between mammographic breast density, hyaluronan synthesis and patient outcome

Very low mammographic breast density predicts poorer outcome in patients with invasive breast cancer

High numbers of macrophages, especially M2-like (CD163-positive), correlate with hyaluronan accumulation and poor outcome in breast cancer

Rab10-mediated endocytosis of the hyaluronan synthase HAS3 regulates hyaluronan synthesis and cell adhesion to collagen

The dynamic metabolism of hyaluronan regulates the cytosolic concentration of UDP-GlcNAc

Borate-aided anion exchange high-performance liquid chromatography of uridine diphosphate-sugars in brain, heart, adipose and liver tissues

Hyaluronan production enhances shedding of plasma membrane-derived microvesicles

Hyaluronan synthase 1 (HAS1) requires higher cellular UDP-GIcNAc concentration than HAS2 and HAS3

Multiple roles of hyaluronan as a target and modifier of the inflammatory response

Cellular Content of UDP-N-acetylhexosamines Controls Hyaluronan Synthase 2 Expression and Correlates with O-Linked N-Acetylglucosamine Modification of Transcription Factors YY1 and SP1

Downregulation of PPARs and SREBP by acyl-CoA-binding protein overexpression in transgenic rats

Effect of medium- and long-chain fatty acid diets on PPAR and SREBP-1 expression and glucose homeostasis in ACBP-overexpressing transgenic rats

Evaluation of Phenotypic Changes of Acyl-CoA Binding Protein / Diazepam Binding Inhibitor Overexpression in Transgenic Mice and Rats

Diazepam binding inhibitor overexpression in mice causes hydrocephalus, decreases plasticity in excitatory synapses and impairs hippocamus-depend learning

Food-induced expression of orexin receptors in rat duodenal mucosa regulates the bicarbonate secretory response to orexin-A

Screening for human cationic trypsinogen (PRSS1) and trypsinogen inhibitor gene (SPINK1) mutations in a Finnish family with hereditary pancreatitis

Duodenal diazepam-binding protein expression and plasma cholecystokinin after alcoholic pancreatitis

VEGF-A, VEGF-D, VEGF receptor-1, VEGF receptor-2, NF-kappaB, and RAGE in atherosclerotic lesions of diabetic Watanabe heritable hyperlipidemic rabbits

Introduction of histidine residues into avidin subunit interfaces allows pH-dependet regulation of quaternary structure and biotin binding

The STC-1 cells express functional orexin-A receptors coupled to CCK release