Hani El-Nezamy
Professor
Gut Health and Food Safety Research Laboratory (GHFS)
Institute of Public Health and Clinical Nutrition, School of Medicine, Faculty of Health Sciences
Research in GHFS laboratory has three focal areas:
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Modulation of gut health parameters by probiotics and bioactive components in food.
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Microbial therapy as an approach for management of liver diseases.
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Gut microbiota in health and diseases.
Research groups
Projects
Publications
102/102 items-
Advanced Microbiome Therapeutics Accelerate MASLD Recovery by Restoring Intestinal Microbiota Equilibrium and the Gut-Liver Axis in a Mouse Model
Lok, Johnson; Chen, Congjia; Iannone, Valeria; Babu, Ambrin Farizah; Lo, Emily Kwun Kwan; Vazquez-Uribe, Ruben; Vaaben, Troels Holger; Kettunen, Mikko; Savolainen, Otto; Schwab, Ursula; Sommer, Morten Otto Alexander; Hanhineva, Kati; Kolehmainen, Marjukka; El-Nezami, Hani; Gómez-Gallego, Carlos, 2025, Journal of agricultural and food chemistry, 73, 24, 15199–15214. A1 Journal article (refereed), original research -
Alpha-aminobutyric Acid Ameliorates Diet-induced Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) Progression in Mice via Enhancing AMPK/SIRT1 Pathway and Modulating the Gut-Liver Axis
Felicianna; Lo, Emily Kwun Kwan; Chen, Congjia; Ismaiah, Marsena Jasiel; Zhang, Fangfei; Leung, Hoi Kit Matthew; El-Nezami, Hani, 2025, Journal of nutritional biochemistry, 140, 109885. A1 Journal article (refereed), original research -
Alpha-aminobutyric acid administration suppressed visceral obesity and modulated hepatic oxidized PUFA metabolism via gut microbiota modulation
Ismaiah, Marsena Jasiel; Kwan Lo, Emily Kwun; Chen, Congjia; Shing-Jie Tsui, Jacob; Johnson-Hill, Winifred Audrey; Felicianna; Zhang, Fangfei; Matthew Leung, Hoi Kit; Oger, Camille; Durand, Thierry; Chung-Yung Lee, Jetty; El-Nezami, Hani, 2025, Free radical biology and medicine, 232, 86-96. A1 Journal article (refereed), original research -
Deoxynivalenol modulated mucin expression and proinflammatory cytokine production, affecting susceptibility to enteroinvasive <i>Escherichia coli</i> infection in intestinal epithelial cells
Wan, Murphy Lam Yim; Co, Vanessa Anna; Turner, Paul C; Nagendra, Shah P; El‐Nezami, Hani, 2025, Journal of food science, 90, 2, e70079. A1 Journal article (refereed), original research -
Probiotics Mixture, Prohep: a Potential Adjuvant for Low-Dose Sorafenib in Metabolic Dysfunction–Associated Steatotic Liver Disease–Associated Hepatocellular Carcinoma Suppression Through Modulating Gut Microbiota
Zhang, Fangfei; Lo, Emily Kwun Kwan; Chen, Congjia; Lee, Jetty Chung-Yung; Felicianna; Ismaiah, Marsena Jasiel; Leung, Hoi Kit Matthew; Tsang, Dorothy Hin Lam; El-Nezami, Hani, 2025, Probiotics and antimicrobial proteins, 18, 1, 956-972. A1 Journal article (refereed), original research -
The effect of aldafermin expressing-Escherichia coli Nissle 1917 along with dietary change on visceral adipose tissue in MASLD mouse model
Iannone, Valeria; Vaittinen, Maija; Gómez-Gallego, Carlos; Mikkonen, Santtu; Lok, Johnson; D’Auria, Giuseppe; Vazquez-Uribe, Ruben; Tikkanen, Ida; Sommer, Morten Otto Alexander; El-Nezami, Hani; Kolehmainen, Marjukka, 2025, International journal of obesity, 49, 7, 1334-1344. A1 Journal article (refereed), original research -
Theabrownin combined with zearalenone suppresses colitis-associated colorectal cancer by inhibiting PI3K/AKT pathway and enhancing microbial propionate production
Leung, Hoi Kit Matthew; Lo, Emily Kwun Kwan; Chen, Congjia; Zhang, Fangfei; Felicianna; Ismaiah, Marsena Jasiel; El-Nezami, Hani, 2025, Scientific reports, 15, 1, 26386. A1 Journal article (refereed), original research -
Toxicological and nutritional evaluation of plant cell cultures from scurvy grass (Cochlearia danica) and rowan (Sorbus aucuparia)
Felicianna; Cheung, Ho Lam; Lo, Emily Kwun Kwan; Zhang, Fangfei; Leung, Hoi Kit Matthew; Ismaiah, Marsena Jasiel; Rosa-Sibakov, Natalia; Iannone, Valeria; Gómez-Gallego, Carlos; Kolehmainen, Marjukka; Rischer, Heiko; Nordlund, Emilia; El-Nezami, Hani, 2025, Frontiers in toxicology, 7, 1655489. A1 Journal article (refereed), original research -
Bioavailability and interactions of schisandrin B with 5-fluorouracil in a xenograft mouse model of colorectal cancer
Lee, Pui-Kei; Co, Vanessa Anna; Yang, Yang; Wan, Murphy Lam Yim; El-Nezami, Hani; Zhao, Danyue, 2024, Food chemistry, 463, 141371. A1 Journal article (refereed), original research -
Engineered Escherichia coli Nissle 1917 Expressing IGF1 and FGF19 Reduce Liver Fat Accumulation and Restore Microbial Equilibrium in a Metabolic Dysfunction-Associated Steatotic Liver Disease Mice Model
Lok, Johnson; Iannone, Valeria; Gómez-Gallego, Carlos; Vazquez-Uribe, Ruben; Sommer, Morten Otto Alexander; Kolehmainen, Marjukka; El-Nezami, Hani, 2024, Proceedings. Abstract