Hani El-Nezamy
Professor
Gut Health and Food Safety Research Laboratory (GHFS)
Institute of Public Health and Clinical Nutrition, School of Medicine, Faculty of Health Sciences
[email protected] | +358 40 591 5137
Research in GHFS laboratory has three focal areas:
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Modulation of gut health parameters by probiotics and bioactive components in food.
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Microbial therapy as an approach for management of liver diseases.
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Gut microbiota in health and diseases.
Research groups
Projects
Publications
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Bioavailability and interactions of schisandrin B with 5-fluorouracil in a xenograft mouse model of colorectal cancer
Lee, Pui-Kei; Co, Vanessa Anna; Yang, Yang; Wan, Murphy Lam Yim; El-Nezami, Hani; Zhao, Danyue. 2024. Food chemistry. 2025; 463: A1 Journal article (refereed), original research -
MRGPRB2/X2 and the analogous effects of its agonist and antagonist in DSS-induced colitis in mice
Duraisamy, Karthi; Kumar, Mukesh; Nawabjan, Abdullah; Lo, Emily Kwun Kwan; hui Lin, Ming; Lefranc, Benjamin; Bonnafé, Elsa; Treilhou, Michel; El-Nezami, Hani; Leprince, Jérôme; Chow, Billy KC. 2024. Biomedicine and pharmacotherapy. 174: A1 Journal article (refereed), original research -
Modulation of Gut Microbial Biomarkers and Metabolites in Cancer Management by Tea Compounds
Leung, Hoi Kit Matthew; Lo, Emily Kwun Kwan; Zhang, Fangfei; Felicianna; Ismaiah Marsena Jasiel; Chen, Congjia; El-Nezami, Hani. 2024. International journal of molecular sciences. 25: A2 Review article, Literature review, Systematic review -
PNPLA3 Genotype and Dietary Fat Modify Concentrations of Plasma and Fecal Short Chain Fatty Acids and Plasma Branched-Chain Amino Acids
Tauriainen, Milla-Maria; Csader, Susanne; Lankinen, Maria; Lo, Kwun Kwan; Chen, Congjia; Lahtinen, Olli; El-Nezamy, Hani; Laakso, Markku; Schwab, Ursula. 2024. Nutrients. 16: A1 Journal article (refereed), original research -
Probiotic Mixture Ameliorates a Diet-Induced MASLD/MASH Murine Model through the Regulation of Hepatic Lipid Metabolism and the Gut Microbiome
Zhang, Fangfei; Lo, Emily Kwun Kwan; Chen, Jiarui; Wang, Ke; Felicianna; Ismaiah, Marsena Jasiel; Leung, Hoi Kit Matthew; Zhao, Danyue; Lee, Jetty Chung-Yung; El-Nezami, Hani. 2024. Journal of agricultural and food chemistry. 72: 8536-8549 A1 Journal article (refereed), original research -
Schisandrin B Suppresses Colon Cancer Growth by Inducing Cell Cycle Arrest and Apoptosis: Molecular Mechanism and Therapeutic Potential
Co, Vanessa Anna; El-Nezami, Hani; Liu, Yawen; Twum, Bonsra; Dey, Priyanka; Cox, Paul A; Joseph, Shalu; Agbodjan-Dossou, Roland; Sabzichi, Mehdi; Draheim, Roger; Wan, Murphy Lam Yim. 2024. ACS pharmacology & translational science. 7: 863-877 A1 Journal article (refereed), original research -
The impact of intermittent fasting on gut microbiota: a systematic review of human studies
Paukkonen, Isa; Törrönen, Elli-Noora; Lok, Johnson; Schwab, Ursula; El-Nezami, Hani. 2024. Frontiers in nutrition. 11: 1-17 A2 Review article, Literature review, Systematic review -
ZnO Nanoparticles as Potent Inducers of Dermal Immunosuppression in Contact Hypersensitivity in Mice
Wang, Shuyuan; Ilves, Marit; Mäenpää, Kuunsäde; Zhao, Lan; El-Nezami, Hani; Karisola, Piia; Alenius, Harri. 2024. Acs nano. 18: 29479-29491 A1 Journal article (refereed), original research -
Associations of altered hepatic gene expression in American lifestyle-induced obesity syndrome diet-fed mice with metabolic changes during NAFLD development and progression
Iannone, V; Lok, J; Babu, AF; Gómez-Gallego, C; Willman, RM; Koistinen, VM; Klåvus, A; Kettunen, MI; Kårlund, A; Schwab, U; Hanhineva, K; Kolehmainen, M; Nezami, H El. 2023. Journal of nutritional biochemistry. 115: A1 Journal article (refereed), original research -
Changes in liver metabolic pathways demonstrate efficacy of the combined dietary and microbial therapeutic intervention in MASLD mouse model
Iannone, Valeria; Babu, Ambrin Farizah; Lok, Johnson; Gómez-Gallego, Carlos; D’Auria, Giuseppe; Vazquez-Uribe, Ruben; Vaaben, Troels Holger; Bongers, Mareike; Mikkonen, Santtu; Vaittinen, Maija; Tikkanen, Ida; Kettunen, Mikko; Klåvus, Anton; Sehgal, Ratika; Kaminska, Dorota; Pihlajamaki, Jussi; Hanhineva, Kati; El-Nezami, Hani; Alexander Sommer, Morten Otto; Kolehmainen, Marjukka. 2023. Molecular metabolism. 78: A1 Journal article (refereed), original research