Elisa Toropainen
Senior Researcher
School of Pharmacy, Faculty of Health Sciences
[email protected] | +358 40 355 2732
Research groups
Publications
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Overproduction of 42 Amino Acids Long Amyloid Beta Leads to Activation of Secretory Autophagy and Development of Drusen‐Like Structures Originating From Retinal Pigment Epithelium
Ruuth, Johanna; Tamminen, Toni; Toropainen, Elisa; Tanila, Heikki; Hyttinen, Juha MT; Malm, Tarja; Kaarniranta, Kai; Koskela, Ali, 2026, Faseb journal, 40, 5, e71608. A1 Journal article (refereed), original research -
Solid-state effects of Brinzolamide on sustained intravitreal release from hot-melt extruded PLGA implants
Sorsa, Teemu; Pilipenko, Iuliia; Valkama, Eetu; Kähärä, Helena; Marczak, Marcin; Pasha, Mehrdad; Puranen, Jooseppi; Kolehmainen, Ida; Koskela, Ali; Paterno, Jussi; Toropainen, Elisa; del Amo, Eva M; Urtti, Arto; Garin, Matthieu; Subrizi, Astrid, 2026, International journal of pharmaceutics, 702, 127278. A1 Journal article (refereed), original research -
Sustained intravitreal dissolution and kinase inhibition by an inhibitory cGMP analogue after its injection as a suspension of a poorly soluble salt
Valkama, Eetu; Toropainen, Elisa; Singh, Simar Pal; Valtari, Annika; Koskela, Ali; Merivaara, Arto; Perez, Oswaldo; Ruponen, Marika; Groten, John; Schipper, Nicolaas; Urtti, Arto; Vellonen, Kati-Sisko; Lajunen, Tatu; Puranen, Jooseppi, 2026, Biomedicine and pharmacotherapy, 199, 119387. A1 Journal article (refereed), original research -
Thermoresponsive hydrogel for long-acting delivery of structurally intact and biologically active Fab fragment and monoclonal antibody
Pilipenko, Iuliia; Stenberg, Katja; Puranen, Jooseppi; Toropainen, Elisa; Määttä, Iida; Jeltsch, Michael; Jauhiainen, Suvi; Nieminen, Tiina; Laakkonen, Johanna P; Ylä-Herttuala, Seppo; Scurti, Elena; Viitala, Tapani; Urtti, Arto; Subrizi, Astrid, 2026, Acta biomaterialia, 219, 167-179. A1 Journal article (refereed), original research -
Drug release and pharmacokinetics of intravitreal liposomal injections: a case study with cyclic guanosine monophosphate derivative
Valkama, Eetu; Sadeghi, Amir; Toropainen, Elisa; Perez, Oswaldo; Schipper, Nicolaas; Ruponen, Marika; Urtti, Arto; Lajunen, Tatu, 2025, European journal of pharmaceutical sciences, 214, 107291. A1 Journal article (refereed), original research -
Intravitreal Sustained Release of Dexamethasone from a Self-Healing Injectable Hydrogel: An In Vivo Safety and Release Study
Annala, Ada; Sadeghi, Amir; Toropainen, Elisa; Valtari, Annika; Puranen, Jooseppi; Paterno, Jussi J; Pirskanen, Lea; Vellonen, Kati-Sisko; Hennink, Wim E; Ruponen, Marika; Vermonden, Tina; Urtti, Arto, 2025, Molecular pharmaceutics, 22, 11, 6920-6931. A1 Journal article (refereed), original research -
Melanin-Binding-Based Discovery of Topically Instilled Carbonic Anhydrase Inhibitors for Targeted Delivery and Prolonged Action in the Eye
Valtari, Annika; Kalinin, Stanislav; Jäntti, Janika; Vanhanen, Pekka; Martina, Hanzlikova; Arun, Tonduru; Katja, Stenberg; Tapani, Viitala; Vellonen, Kati-Sisko; Toropainen, Elisa; Ruponen, Marika; Urtti, Arto, 2025, Molecular pharmaceutics, 22, 2, 721-732. A1 Journal article (refereed), original research -
New insights on liposomal formulations based upon tear film lipids: A combined study of safety and ocular surface pharmacokinetics
Jäntti, Janika; Puranen, Jooseppi; Merivaara, Arto; Balla, Anusha; Tuomikoski, Eveliina; Paterno, Jussi; Toropainen, Elisa; Raitanen, Jan-Erik; Lajunen, Tatu; Ekholm, Filip. S; Ruponen, Marika, 2025, European journal of pharmaceutical sciences, 215, 107282. A1 Journal article (refereed), original research -
Progressive rod bipolar cell loss, ubiquitin accumulation, and subretinal drusenoid deposits in Cln3Δex7/8 mice: New insights into juvenile neuronal ceroid lipofuscinosis pathogenesis
Torsti, Tommi; Tamminen, Toni; Toropainen, Elisa; Jalkanen, Aaro; Kauppinen, Anu; Kaarniranta, Kai; Forsberg, Markus M, 2025, Experimental eye research, 263, 110766. A1 Journal article (refereed), original research -
Rapid elimination of suprachoroidally injected small molecule drugs into the systemic blood circulation
Laitinen, Jonna; Valkama, Eetu; Valtari, Annika; Toropainen, Elisa; Koskela, Ali; Kolehmainen, Ida; Puranen, Jooseppi; del Amo, Eva M.; Vellonen, Kati-Sisko; Subrizi, Astrid; Urtti, Arto, 2025, European journal of pharmaceutical sciences, 215, 107349. A1 Journal article (refereed), original research