Research groups
Publications
33/33 items-
Thapsigargin-induced autophagic flux impairment and inflammation are potentiated by CLN3 deficiency and alleviated by 5-aminoimidazole-4-carboxamide ribonucleoside (AICAR) in human ARPE-19 cells
Torsti, Tommi; Hytti, Maria; Toppila, Maija; Forsberg, Markus M; Kauppinen, Anu, 2026, Biochemical and biophysical research communications, 829, 154157. A1 Journal article (refereed), original research -
Anti-inflammatory potential of simvastatin and amfenac in ARPE-19 cells; insights in preventing re-detachment and proliferative vitreoretinopathy after rhegmatogenous retinal detachment surgery
Harju, Niina; Hytti, Maria; Kolari, Onni; Nisula, Hilkka; Loukovaara, Sirpa; Kauppinen, Anu, 2024, International ophthalmology, 44, 1, 158. A1 Journal article (refereed), original research -
Epithelial-mesenchymal Transition (EMT) and the Effect of Atorvastatin on it in ARPE-19 cells
Mysore, Yashavanthi; Hytti, Maria; Deen, Ashik Jawahar; Ranta-aho, Sofia; Piippo, Niina; Toppila, Maija; Loukovaara, Sirpa; Harju, Niina; Kauppinen, Anu, 2024, Cell biochemistry and biophysics, 82, 2, 1523-1536. A1 Journal article (refereed), original research -
Metformin Alleviates Inflammation and Induces Mitophagy in Human Retinal Pigment Epithelium Cells Suffering from Mitochondrial Damage
Toppila, Maija; Ranta-aho, Sofia; Kaarniranta, Kai; Hytti, Maria; Kauppinen, Anu, 2024, Cells, 13, 17, 1433. A1 Journal article (refereed), original research -
Oxidative Stress and Inflammation-Related mRNAs Are Elevated in Serum of a Finnish Wet AMD Cohort
Liukkonen, Mikko; Heloterä, Hanna; Siintamo, Leea; Ghimire, Bishwa; Mattila, Pirkko; Kivinen, Niko; Kostanek, Joanna; Watala, Cezary; Hytti, Maria; Hyttinen, Juha; Koskela, Ali; Blasiak, Janusz; Kaarniranta, Kai, 2024, Investigative ophthalmology and visual science, 65, 13, 30. A1 Journal article (refereed), original research -
Cis-urocanic acid improves cell viability and suppresses inflammasome activation in human retinal pigment epithelial cells
Korhonen, Eveliina; Piippo, Niina; Hytti, Maria; Kaarniranta, Kai; Kauppinen, Anu, 2023, Biochemical pharmacology, 216, 115790. A1 Journal article (refereed), original research -
Crosstalk of protein clearance, inflammasome, and Ca2+ channels in retinal pigment epithelium derived from age-related macular degeneration patients
Karema-Jokinen, Viivi; Koskela, Ali; Hytti, Maria; Hongisto, Heidi; Viheriälä, Taina; Liukkonen, Mikko; Torsti, Tommi; Skottman, Heli; Kauppinen, Anu; Nymark, Soile; Kaarniranta, Kai, 2023, Journal of biological chemistry, 299, 6, 104770. A1 Journal article (refereed), original research -
The Prolyl Oligopeptidase Inhibitor KYP-2047 Is Cytoprotective and Anti-Inflammatory in Human Retinal Pigment Epithelial Cells with Defective Proteasomal Clearance
Toppila, Maija; Hytti, Maria; Korhonen, Eveliina; Ranta-aho, Sofia; Harju, Niina; Forsberg, Markus M.; Kaarniranta, Kai; Jalkanen, Aaro; Kauppinen, Anu, 2023, Antioxidants, 12, 6, 1279. A1 Journal article (refereed), original research -
Amfenac together with simvastatin reduces IL-8 and MCP-1 and increases VEGF release from ARPE-19 cells upon inflammatory conditions
Bhattarai, Niina; Hytti, Maria; Kolari, Onni; Nisula, Hilkka; Loukovaara, Sirpa; Kauppinen, Anu, 2022, Acta ophthalmologica. Abstract -
Epoxomicin, a Selective Proteasome Inhibitor, Activates AIM2 Inflammasome in Human Retinal Pigment Epithelium Cells
Sridevi Gurubaran, Iswariyaraja; Hytti, Maria; Kaarniranta, Kai; Kauppinen, Anu, 2022, Antioxidants, 11, 7, 1288. A1 Journal article (refereed), original research