Anna-Liisa Levonen-Harju
1st Vice-Dean
Professor
A.I. Virtanen Institute for Molecular Sciences, Faculty of Health Sciences
anna-liisa.levonen-harju@uef.fi | +358 40 358 9907
Research groups
Projects
Publications
82/82 items-
Electrophilic metabolites targeting the KEAP1/NRF2 partnership
Dinkova-Kostova, Albena T; Hakomäki, Henriikka; Levonen, Anna-Liisa. 2024. Current opinion in chemical biology. 78: A2 Review article, Literature review, Systematic review -
Metabolic effects of nuclear receptor activation in vivo after 28-day oral exposure to three endocrine-disrupting chemicals
Attema, Brecht; Kummu, Outi; Pitkänen, Sini; Weisell, Jonna; Vuorio, Taina; Pennanen, Erika; Vorimo, Maria; Rysä, Jaana; Kersten, Sander; Levonen, Anna-Liisa; Hakkola, Jukka. 2024. Archives of toxicology. 98: 911-928 A1 Journal article (refereed), original research -
Oncogenic KEAP1 mutations activate TRAF2-NFκB signaling to prevent apoptosis in lung cancer cells
Deen, Ashik Jawahar; Adinolfi, Simone; Härkönen, Jouni; Patinen, Tommi; Liu, Xiaonan; Laitinen, Tuomo; Takabe, Piia; Kainulainen, Kirsi; Pasonen-Seppänen, Sanna; Gawriyski, Lisa M; Arasu, Uma Thanigai; Selvarajan, Ilakya; Mäkinen, Petri; Laitinen, Hanna; Kansanen, Emilia; Kaikkonen, Minna U; Poso, Antti; Varjosalo, Markku; Levonen, Anna-Liisa. 2024. Redox biology. 69: A1 Journal article (refereed), original research -
A pan-cancer analysis shows immunoevasive characteristics in NRF2 hyperactive squamous malignancies
Härkönen, Jouni; Pölönen, Petri; Deen, Ashik Jawahar; Selvarajan, Ilakya; Teppo, Hanna-Riikka; Dimova, Elitsa Y.; Kietzmann, Thomas; Ahtiainen, Maarit; Väyrynen, Juha P.; Väyrynen, Sara A.; Elomaa, Hanna; Tynkkynen, Niko; Eklund, Tiia; Kuopio, Teijo; Talvitie, Eva-Maria; Taimen, Pekka; Kallajoki, Markku; Kaikkonen, Minna U.; Heinäniemi, Merja; Levonen, Anna-Liisa. 2023. Redox biology. 61: A1 Journal article (refereed), original research -
Genetic variation is a key determinant of chromatin accessibility and drives differences in the regulatory landscape of C57BL/6J and 129S1/SvImJ mice
Mononen, Juho; Taipale, Mari; Malinen, Marjo; Velidendla, Bharadwaja; Niskanen, Einari; Levonen, Anna-Liisa; Ruotsalainen, Anna-Kaisa; Heikkinen, Sami. 2023. Nucleic acids research. 2024; 52: 2904-2923 A1 Journal article (refereed), original research -
PI3Kβ inhibition enhances ALK ‐inhibitor sensitivity in ALK‐rearranged lung cancer
Talwelkar, Sarang S; Mäyränpää, Mikko I; Schüler, Julia; Linnavirta, Nora; Hemmes, Annabrita; Adinolfi, Simone; Kankainen, Matti; Sommergruber, Wolfgang; Levonen, Anna‐Liisa; Räsänen, Jari; Knuuttila, Aija; Verschuren, Emmy W.; Wennerberg, Krister. 2023. Molecular oncology. 17: 747-764 A1 Journal article (refereed), original research -
The KEAP1-NRF2 pathway: Targets for therapy and role in cancer
Adinolfi, Simone; Patinen, Tommi; Jawahar Deen, Ashik; Pitkänen, Sini; Härkönen, Jouni; Kansanen, Emilia; Küblbeck, Jenni; Levonen, Anna-Liisa. 2023. Redox biology. 63: A2 Review article, Literature review, Systematic review -
A novel uterine leiomyoma subtype exhibits NRF2 activation and mutations in genes associated with neddylation of the Cullin 3-RING E3 ligase
Mehine, Miika; Ahvenainen, Terhi; Khamaiseh, Sara; Härkönen, Jouni; Reinikka, Siiri; Heikkinen, Tuomas; Äyräväinen, Anna; Pakarinen, Päivi; Härkki, Päivi; Pasanen, Annukka; Levonen, Anna-Liisa; Bützow, Ralf; Vahteristo, Pia. 2022. Oncogenesis. 11: . 52 A1 Journal article (refereed), original research -
Global MicroRNA Profiling of Vascular Endothelial Cells
Schmauch, Eloi; Levonen, Anna-Liisa; Linna-Kuosmanen, Suvi. Teoksessa: Fiedler, L.R.; Pellet-Many, C(toim.) , 2022. VEGF Signaling. s. 157-186. Humana press A3 Book section, Chapters in research books -
A toxicogenomic data space for system-level understanding and prediction of EDC-induced toxicity
Sakhteman, A; Failli, M; Kublbeck, J; Levonen, AL; Fortino, V. 2021. Environment international. 156: 106751 A1 Journal article (refereed), original research