Anne Lecklin

Geeniterapiasta uutta toivoa virtsarakon syöpää sairastaville

Helminen, Jesse; Nissinen, Joonas; Lecklin, Anne, 2025, Dosis, 41, 3, 394-404. B1 Non-refereed journal articles

Tirtsepatidi, GLP-1:n ja GIP:n reseptoreiden kaksoisagonisti tyypin 2 diabeteksen ja lihavuuden hoidossa

Tompuri, Sini; Lecklin, Anne, 2025, Dosis, 41, 4, 516-530. A2 Review article, Literature review, Systematic review

Dosiksen 40. vuosikerta tuo mukanaan uudistuksia

Ritala-Nurmi, Anneli; Holmström, Anna-Riia; Hämeen-Anttila, Katri; Lecklin, Anne; Linden, Kari; Palmgren, Joni; Pohjanoksa-Mäntylä, Marika; Turunen, Jenni, 2024, Dosis, 40, 1, 5-7. B1 Non-refereed journal articles

Parenteraalisesta mikrobilääkehoidosta raportoidut vaaratapahtumat tehohoidossa vuosina 2007-2017

Kurttila, Minna; Heikkinen, Susanna; Saano, Susanna; Lecklin, Anne; Laaksonen, Raisa, 2024, Dosis, 40, 1, 8-27. A1 Journal article (refereed), original research

Adolescent inpatients with a depressive disorder: Treatment outcomes and psychopharmacological medication

Snellman, Viivi; Lecklin, Anne; Laukkanen, Eila, 2023, Psychiatria Fennica, 54, 80-95. A1 Journal article (refereed), original research

Psychiatric inpatient treatment of fostered adolescents with a depressive disorder is not very effective

Snellman, Viivi; Lecklin, Anne; Laukkanen, Eila, 2023, Psychiatria Fennica, 54, 96-109. A1 Journal article (refereed), original research

A retrospective study of hospitalized adolescents suffering from depressive conduct disorder

Lecklin, Anne; Snellman, Viivi; Torhola, Emmi; Liuska, Päivi; Kärkkäinen, Milla; Similä, Elina; Laukkanen, Eila, 2022, Psychiatria Fennica, 53, 154-167. A1 Journal article (refereed), original research

#dosisfarma - päivitetyt kirjoitusohjeet, sidonnaisuudet & Dosis-webinaari

Ritala-Nurmi, Anneli; Hämeen-Anttila, Katri; Kataja, Antti; Lecklin, Anne; Matikainen, Minna; Palmgren, Joni; Pohjanoksa-Mäntylä, Marika, 2020, Dosis, 36, 1, 3-4. B1 Non-refereed journal articles

Näyttö masennuslääkkeiden hyödyistä lapsen ja nuoren masennuksen hoidossa vähäinen

Vartiainen, Jasmin; Snellman, Viivi; Laukkanen, Eila; Lecklin, Anne, 2020, Dosis, 36, 2, 196-215. A2 Review article, Literature review, Systematic review

Retrospektiivinen tutkimus lääkehoidosta osana laihuushäiriöpotilaiden osastohoitoa

Snellman Viivi, Laukkanen Eila, Lecklin Anne, 2016, Dosis, 32, 2, 97-108. A1 Journal article (refereed), original research

Syömishäiriöiden psyykenlääkehoidosta tarvitaan lisää tutkimustietoa [Teemat: Psyyke ja lääke]

Snellman Viivi, Laukkanen Eila, Lecklin Anne, 2016, Sic!, 6, 2, 26-29. D1 Article in a trade journal

Psychopharmacology as part of treatment of anorexia nervosa inpatients: a clinical retrospective study

Snellman Viivi, Laukkanen Eila, Lecklin Anne, 2015, Psychiatria fennica, 46, 32-44. A1 Journal article (refereed), original research

Biologiset lääkkeet tuovat uusia mahdollisuuksia vaikean nivelreuman hoitoon

Lecklin Anne, 2014, NIVELTIETO, 2, 9-11. D1 Article in a trade journal

Miten nivelreumaa hoidetaan tänään? [kuukauden kysymys]

Lecklin Anne, 2013, Suomen apteekkarilehti, 3/13, 30-33. D1 Article in a trade journal

Tyrosine hydroxylase gene transfections to different sites of striatum in the rat model of Parkinson's disease

Raasmaja Atso, Lehtonen Sarka, Kääriäinen Tiina, Lampela Pasi, Huotari Marko, Lecklin Anne, 2013, Open Journal of Genetics, 3, 30-37. A1 Journal article (refereed), original research

A water-alcohol extract of Citrus grandis whole fruits has beneficial metabolic effects in the obese Zucker rats fed with high fat/high cholesterol diet

Raasmaja Atso, Lecklin Anne, Li Xiang M, Zou Jianqiang, Zhu Guo-Guang, Laakso Into, Hiltunen Raimo, 2012, Food chemistry, 2013:138, 1392-1399. A1 Journal article (refereed), original research

Mitä uutta tyypin 2 diabeteksen hoidossa? [Kuukauden kysymys]

Lecklin Anne, 2012, Suomen apteekkarilehti, 101, 10, 36-37. D1 Article in a trade journal

Distinct effects of calorie restriction and resveratrol on diet-induced obesity and fatty liver formation

Tauriainen Eveliina, Luostarinen Mira, Martonen Essi, Finckenberg Piet, Kovalainen Miia, Huotari Anne, Herzig Karl-Heinz, Lecklin Anne, Mervaala Eero, 2011, Journal of nutrition and metabolism, 2011, 525094. A1 Journal article (refereed), original research

Sample purification improves the analysis of nonviral in vivo gene transfection

Soininen P, Hanzlíková M, Paukkunen M, Lecklin A, Männistö P & Raasmaja A, 2010, Plasmid, 63, 27-30. A1 Journal article (refereed), original research

Lack of robust protective effect of quercetin in two types of 6-hydroxydopamine-induced parkinsonian models in rats and dopaminergic cell cultures

Kääriäinen TM, Piltonen M, Ossola B, Kekki H, Lehtonen S, Nenonen T, Lecklin A, Raasmaja A, Männistö PT, 2008, Brain research, 1203, 149-159. A1 Journal article (refereed), original research

Neuroanatomical mapping of juvenile rat brain regions with prominent basal signal in [35S]GTPgammaS autoradiography

Aaltonen N, Palomäki VAB, Lecklin A, Laitinen JT, 2008, Journal of chemical neuroanatomy, 35, 233-241. A1 Journal article (refereed), original research

Increased leptin expression in the dorsal vagal complex suppresses adiposity without affecting energy intake and metabolic hormones

Boghossian S, Lecklin A, Dube MG, Kalra PS, Kalra SP, 2006, Obesity, 14, 6, 1003-1009. A1 Journal article (refereed), original research

Perigestational suppression of weight gain with central leptin gene therapy results in lower weight F1 generation

Lecklin A, Dube MG, Torto RN, Kalra PS, Kalra SP, 2005, Peptides, 26, 1176-1187. A1 Journal article (refereed), original research

Suppression of fat deposition for the life time with gene therapy

Boghossian S, Lecklin A, Torto R, Kalra PS, Kalra SP, 2005, Peptides, 26, 1512-1519. A1 Journal article (refereed), original research

Agonists for neuropeptide Y receptors Y1 and Y5 stimulate different phases of feeding in guinea pigs

Lecklin A, Lundell I, Salmela S, Männistö PT, Beck-Sickinger AG, Larhammar D, 2003, British journal of pharmacology, 139, 1433-1440. A1 Journal article (refereed), original research

Inhibition of histamine catabolism suppresses fat intake but not the intake of carbohydrates and protein

Lecklin A, Tuomisto L, 2002, INFLAMMATION RESEARCH. SUPPLEMENT, 51, 53-54. A1 Journal article (refereed), original research

Receptor subtypes Y1 and Y5 mediate neuropeptide Y induced feeding in the guinea-pig

Lecklin A, Lundell I, Paananen L, Wikberg JES, Männistö PT, Larhammar D, 2002, British journal of pharmacology, 135, 2029-2037. A1 Journal article (refereed), original research

Changes in circadian rhythmicity and melatonin balance in rats with portacaval anastomosis (PCA) - relation with histamine

Tuomisto L, Lecklin A, Lozeva V, Hippeläinen M, Valtonen M, 2001, Watanabe T, Timmerman H, Yanai K, Histamine Research in the New Millennium, 193-198. A3 Book section, Chapters in research books

Modifying effects of histamine on circadian rhythms and neuronal excitability

Tuomisto L, Lozeva V, Valjakka A, Lecklin A, 2001, Behavioural brain research, 124, 129-135. A1 Journal article (refereed), original research

An acute i.c.v. infusion of leptin has no effect on hypothalamic histamine and tele-methylhistamine contents in Wistar rats

Lecklin A, Hermonen P, Tarhanen J, Männistö PT, 2000, European journal of pharmacology, 395, 113-119. A1 Journal article (refereed), original research

Effects of mepyramine on circadian locomotor activity in rats with portacaval anastomosis

Lozeva V, Lecklin A, Valjakka A, Hippeläinen M, Tuomisto L, 2000, Yurdaydin C, Bozkaya H, Advances in Hepatic Encephalopathy & Metabolism in Liver Disease, 165-169. A3 Book section, Chapters in research books

Effects of the histamine H1 receptor blocker, pyrilamine, on spontaneous locomotor activity of rats with long-term portacaval anastomosis

Lozeva V, Valjakka A, Lecklin A, Olkkonen H, Hippeläinen M, Itkonen M, Plumed C, Tuomisto L, 2000, Hepatology, 31, 2, 336-344. A1 Journal article (refereed), original research

Metoprine-induced thirst and diuresis in Wistar rats

Lecklin A, Eriksson L, Leppäluoto J, Tarhanen J, Tuomisto L, 1999, Acta physiologica, 165, 325-333. A1 Journal article (refereed), original research

Brain Histamine in the Regulation of Food Intake and Body Water Homeostasis in Rats

Lecklin A, 1998, Kuopion yliopiston julkaisuja A. Farmaseuttiset tieteet. G5 Doctoral dissertation (article)

Effects of intracerebroventricularly infused histamine and selective H1, H2 and H3 agonists on food and water intake and urine flow in Wistar rats

Lecklin A, Etu-Seppälä P, Stark H, Tuomisto L, 1998, Brain research, 793, 279-288. A1 Journal article (refereed), original research

The blockade of H1 receptors attenuates the suppression of feeding and diuresis induced by inhibition of histamine catabolism

Lecklin A, Tuomisto L, 1998, Pharmacology biochemistry and behavior, 59, 3, 753-758. A1 Journal article (refereed), original research

Modification of reproductive function in the rat by 3-methylcholanthrene

Konstandi M, Pappas P, Johnson E, Lecklin A, Karageorgou M, Marselos M, 1997, Pharmacological research, 35, 2, 107-111. A1 Journal article (refereed), original research

Suppression of the acquisition of conditioned avoidance behavior in the rat by 3-methylcholanthrene

Konstandi M, Pappas P, Johnson E, Lecklin A, Marselos M, 1997, Pharmacology biochemistry and behavior, 56, 4, 637-641. A1 Journal article (refereed), original research

Fluid balance in rats of three different strains after inhibition of histamine catabolism

Lecklin A, Tuomisto L, 1995, Physiology and behavior, 58, 5, 861-867. A1 Journal article (refereed), original research

Metoprine, an inhibitor of histamine N-methyltransferase but not catechol-O-methyltransferase, suppresses feeding in sated and in food deprived rats

Lecklin A, Tuomisto L, MacDonald E, 1995, Methods and findings in experimental and clinical pharmacology, 17, 47-52. A1 Journal article (refereed), original research

The effect of metoprine on glucoprivic feeding induced by 2-deoxy-D-glucose

Lecklin A, Järvikylä M, Tuomisto L, 1994, Pharmacology biochemistry and behavior, 49, 4, 853-857. A1 Journal article (refereed), original research

Assessment of acute behavioral toxicity of low doses of diisopropylfluorophosphate (DFP) in rats

Nieminen SA, Sirkka U, Lecklin A, Heikkinen O, Ylitalo P, 1991, Methods and findings in experimental and clinical pharmacology, 13, 9, 617-623. A1 Journal article (refereed), original research

Acute behavioural effects of organophosphates sarin and soman in rats

Nieminen SA, Lecklin A, Heikkinen O, Ylitalo P, 1990, PHARMACOLOGY & TOXICOLOGY, 67, 36-40. A1 Journal article (refereed), original research

Feed intake after inhibition of histamine catabolism

Lecklin A, Tuomisto L, 1990, AGENTS AND ACTIONS, 30, 1/2, 216-219. A1 Journal article (refereed), original research

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Geeniterapiasta uutta toivoa virtsarakon syöpää sairastaville

Tirtsepatidi, GLP-1:n ja GIP:n reseptoreiden kaksoisagonisti tyypin 2 diabeteksen ja lihavuuden hoidossa

Dosiksen 40. vuosikerta tuo mukanaan uudistuksia

Parenteraalisesta mikrobilääkehoidosta raportoidut vaaratapahtumat tehohoidossa vuosina 2007-2017

Adolescent inpatients with a depressive disorder: Treatment outcomes and psychopharmacological medication

Psychiatric inpatient treatment of fostered adolescents with a depressive disorder is not very effective

A retrospective study of hospitalized adolescents suffering from depressive conduct disorder

#dosisfarma - päivitetyt kirjoitusohjeet, sidonnaisuudet & Dosis-webinaari

Näyttö masennuslääkkeiden hyödyistä lapsen ja nuoren masennuksen hoidossa vähäinen

Open Access Dosis ja uusi toimituskunta [Pääkirjoitus]

Biologiset lääkkeet osana aikuisten nivelreuman hoitoa

Lasten psykiatristen häiriöiden lääkehoito ja tavallisimmat lääkkeet

Retrospektiivinen tutkimus lääkehoidosta osana laihuushäiriöpotilaiden osastohoitoa

Syömishäiriöiden psyykenlääkehoidosta tarvitaan lisää tutkimustietoa [Teemat: Psyyke ja lääke]

Psychopharmacology as part of treatment of anorexia nervosa inpatients: a clinical retrospective study

Biologiset lääkkeet tuovat uusia mahdollisuuksia vaikean nivelreuman hoitoon

Miten nivelreumaa hoidetaan tänään? [kuukauden kysymys]

Tyrosine hydroxylase gene transfections to different sites of striatum in the rat model of Parkinson's disease

A water-alcohol extract of Citrus grandis whole fruits has beneficial metabolic effects in the obese Zucker rats fed with high fat/high cholesterol diet

Mitä uutta tyypin 2 diabeteksen hoidossa? [Kuukauden kysymys]

Distinct effects of calorie restriction and resveratrol on diet-induced obesity and fatty liver formation

Sample purification improves the analysis of nonviral in vivo gene transfection

Lack of robust protective effect of quercetin in two types of 6-hydroxydopamine-induced parkinsonian models in rats and dopaminergic cell cultures

Neuroanatomical mapping of juvenile rat brain regions with prominent basal signal in [35S]GTPgammaS autoradiography

Increased leptin expression in the dorsal vagal complex suppresses adiposity without affecting energy intake and metabolic hormones

Perigestational suppression of weight gain with central leptin gene therapy results in lower weight F1 generation

Suppression of fat deposition for the life time with gene therapy

Agonists for neuropeptide Y receptors Y1 and Y5 stimulate different phases of feeding in guinea pigs

Inhibition of histamine catabolism suppresses fat intake but not the intake of carbohydrates and protein

Receptor subtypes Y1 and Y5 mediate neuropeptide Y induced feeding in the guinea-pig

Changes in circadian rhythmicity and melatonin balance in rats with portacaval anastomosis (PCA) - relation with histamine

Modifying effects of histamine on circadian rhythms and neuronal excitability

An acute i.c.v. infusion of leptin has no effect on hypothalamic histamine and tele-methylhistamine contents in Wistar rats

Effects of mepyramine on circadian locomotor activity in rats with portacaval anastomosis

Effects of the histamine H1 receptor blocker, pyrilamine, on spontaneous locomotor activity of rats with long-term portacaval anastomosis

Metoprine-induced thirst and diuresis in Wistar rats

Brain Histamine in the Regulation of Food Intake and Body Water Homeostasis in Rats

Effects of intracerebroventricularly infused histamine and selective H1, H2 and H3 agonists on food and water intake and urine flow in Wistar rats

The blockade of H1 receptors attenuates the suppression of feeding and diuresis induced by inhibition of histamine catabolism

Modification of reproductive function in the rat by 3-methylcholanthrene

Suppression of the acquisition of conditioned avoidance behavior in the rat by 3-methylcholanthrene

Fluid balance in rats of three different strains after inhibition of histamine catabolism

Metoprine, an inhibitor of histamine N-methyltransferase but not catechol-O-methyltransferase, suppresses feeding in sated and in food deprived rats

The effect of metoprine on glucoprivic feeding induced by 2-deoxy-D-glucose

Assessment of acute behavioral toxicity of low doses of diisopropylfluorophosphate (DFP) in rats

Acute behavioural effects of organophosphates sarin and soman in rats

Feed intake after inhibition of histamine catabolism