Inhalation Toxicology Laboratory

Research group

01.01.2010 -

Department of Environmental and Biological Sciences, Faculty of Science, Forestry and Technology

Information People Publications

The research of the Inhalation Toxicology Laboratory is focused on toxicological effects of inhalable environmental exposures in the immune system. Our aim is to identify the actual causes of health effects by using cell lines, experimental animals and clinical samples. The research is conducted using multidisciplinary approach in collaboration with experts in e.g. aerosol physics, combustion technology, microbiology, epidemiology and modeling.

We study how environmental exposures such as combustion emissions, outdoor and indoor air particulate matter, microbes and chemicals activate toxicological mechanisms leading to adverse health effects. In addition, we are also interested in the protective role of exposure to environmental microbes during childhood, e.g. their effect on the maturation of immune responses and development of asthma and allergies.

Teams

Immunotoxicology of environmental exposures

Marjut Roponen

Toxicology of air pollutants

Pasi Jalava

Keywords

environmental health environmental health risk assessment environmental toxicology indoor air inhalation toxicology intola outdoor air

Professors

Post-doctoral Researchers

Maria-Viola Martikainen

Visiting Researcher

Department of Environmental and Biological Sciences, Faculty of Science, Forestry and Technology

Inhalation Toxicology Laboratory

Teams

Immunotoxicology of environmental exposures

Toxicology of air pollutants

Keywords

Professors

Marjut Roponen

Pasi Jalava

Post-doctoral Researchers

Maria-Viola Martikainen

Doctoral Researchers

Henri Hakkarainen

Tarleena Tossavainen

Visiting researcher

Other group members

Immune Responsiveness to LPS Determines Risk of Childhood Wheeze and Asthma in 17q21 Risk Allele Carriers

A review of microbial and chemical assessment of indoor surfaces

Associations of Particulate Matter Sizes and Chemical Constituents with Blood Lipids: A Panel Study in Guangzhou, China

Cell membrane coating integrity affects the internalization mechanism of biomimetic nanoparticles

Early age exposure to moisture and mould is related to FeNO at the age of 6 years

Genotoxic and inflammatory effects of spruce and brown coal briquettes combustion aerosols on lung cells at the air-liquid interface

Household solid waste combustion with wood increases particulate trace metal and lung deposited surface area emissions

Microbial exposures in moisture-damaged schools and associations with respiratory symptoms in students: A multi-country environmental exposure study

Mitogen-activated protein kinase signaling in childhood asthma development and environment-mediated protection

Perfluorooctanesulfonate and perfluorooctanoate exacerbate airway inflammation in asthmatic mice and in vitro

Short-Term Effects of Particle Size and Constituents on Blood Pressure in Healthy Young Adults in Guangzhou, China

Short-Term Effects of Particle Sizes and Constituents on Blood Biomarkers among Healthy Young Adults in Guangzhou, China

Sisäilma, terveys ja riskikäsitykset

The characteristics and size of lung-depositing particles vary significantly between high and low pollution traffic environments

Toxicological and microbiological characterization of cow stable dust

Toxicological transcriptome of human airway constructs after exposure to indoor air particulate matter: In search of relevant pathways of moisture damage-associated health effects

Visualising household air pollution: Colorimetric sensor arrays for monitoring volatile organic compounds indoors

Weathering of Antibacterial Melt-Spun Polyfilaments Modified by Pine Rosin

Air quality intervention during the Nanjing youth olympic games altered PM sources, chemical composition, and toxicological responses

Altistuminen kosteusvaurioituneista taloista kerätyille hiukkasnäytteille aktivoi ilmatiesolukon toksisiin vasteisiin liittyviä geenejä

Association Between Residential Greenness, Cardiometabolic Disorders, and Cardiovascular Disease Among Adults in China

Cryopreservation Affected the Levels of Immune Responses of PBMCs and Antigen-Presenting Cells

Glial smog: Interplay between air pollution and astrocyte-microglia interactions

Greenness surrounding schools is associated with lower risk of asthma in schoolchildren.

Human Airway Construct Model is Suitable for Studying Transcriptome Changes Associated with Indoor Air Particulate Matter Toxicity

Inflammatory responses of urban air PM modulated by chemical composition and different air quality situations in Nanjing, China

Influence of wood species on toxicity of log-wood stove combustion aerosols: a parallel animal and air-liquid interface cell exposure study on spruce and pine smoke

Is PM 1 similar to PM 2.5? A new insight into the association of PM 1 and PM 2.5 with children's lung function

Maturation of the gut microbiome during the first year of life contributes to the protective farm effect on childhood asthma

Modification of caesarean section on the associations between air pollution and childhood asthma in seven Chinese cities

Olfactory cell cultures to investigate health effects of air pollution exposure: implications for neurodegeneration

The role of influenza vaccination in mitigating the adverse impact of ambient air pollution on lung function in children: new insights from the Seven Northeastern Cities Study in China

Thermal dose as a universal tool to evaluate nanoparticle-induced photothermal therapy

Toxicological evaluation of exhaust emissions from light-duty vehicles using different fuel alternatives in sub-freezing conditions

Urban air PM modifies differently immune defense responses against bacterial and viral infections in vitro

Urban air particulate matter induces mitochondrial dysfunction in human olfactory mucosal cells

Voiko sisäilman haitallisuutta arvioida toksisuustesteillä?

Adaptation of Black Carbon Footprint Concept Would Accelerate Mitigation of Global Warming

Ambient Airborne Particulates of Diameter less than or equal to 1 micrometre, a Leading Contributor to the Association Between Ambient Airborne Particulates of Diameter less than or equal to 2.5 micrometres and Children's Blood Pressure

Association Between Greenness Surrounding Schools and Kindergartens and Attention-Deficit/Hyperactivity Disorder in Children in China

Association between antibiotic treatment during pregnancy & infancy and the development of allergic diseases

Association between community greenness and obesity in urban-dwelling Chinese adults

Association of Breastfeeding and Air Pollution Exposure With Lung Function in Chinese Children

Benefits of influenza vaccination on the associations between ambient air pollution and allergic respiratory diseases in children and adolescents: New insights from the Seven Northeastern Cities study in China

Community greenness, blood pressure, and hypertension in urban dwellers: The 33 Communities Chinese Health Study

Emissions from a fast-pyrolysis bio-oil fired boiler: Comparison of health-related characteristics of emissions from bio-oil, fossil oil and wood

Farm-like indoor microbiota in non-farm homes protects children from asthma development

Greenness around schools associated with lower risk of hypertension among children: Findings from the Seven Northeastern Cities Study in China

Keuhkokudoksesta eristetyn RNA:n toksikologinen transkriptomi sisäilmasta kerättyjen hiukkasten terveysvaikutusten tutkimuksessa

Maatalomainen kodin mikrobisto voi suojata astmalta kaupungissakin

Miksi sisäilman haitallisuutta ei voi arvioida toksisuustesteillä?

Oxidative Capacity and Haemolytic Activity of Settled Dust from Moisture-Damaged Schools

Oxidative stress induced by ultrafine carbon black particles can elicit apoptosis in vivo and vitro

Parents know it best: Prediction of asthma and lung function by parental perception of early wheezing episodes

Prenatal exposure to perfluoroalkyl substances is associated with lower hand, foot and mouth disease viruses antibody response in infancy: Findings from the Guangzhou Birth Cohort Study

Residential greenness and blood lipids in urban-dwelling adults: The 33 Communities Chinese Health Study

TNF-α-induced protein 3 is a key player in childhood asthma development and environment-mediated protection

A panel study of airborne particulate matter concentration and impaired cardiopulmonary function in young adults by two different exposure measurement

Design and validation of an air-liquid interface (ALI) exposure device based on thermophoresis

Differences between co-cultures and monocultures in testing the toxicity of particulate matter derived from log wood and pellet combustion

Early age exposure to moisture damage and systemic inflammation at the age of 6 years

Emissions and atmospheric processes influence the chemical composition and toxicological properties of urban air particulate matter in Nanjing, China

Emissions from a modern log wood masonry heater and wood pellet boiler: Composition and biological impact on air-liquid interface exposed human lung cancer cells

High levels of Butyrate and Propionate in early life are associated with protection against atopy

In vitro -solumallit sisäilmasta kerättyjen hiukkasten terveysvaikutusten tutkimuksessa