Steroid Receptor Research Center
Research group
01.01.2019 -
Institute of Biomedicine, School of Medicine, Faculty of Health Sciences
We study the functions of steroid receptors especially in regulation of chromatin and transcription, and the role of these in hormone-driven cancers. Especially, we focus on formation of drug resistance in especially prostate cancer.
Currently, there are five research groups in the SRRC which are led by Prof. Jorma Palvimo, Research Director Leena Latonen, University lecturer Einari Niskanen, and Academy researchers Kirsi Ketola and Ville Paakinaho.
Publications
109 items-
A Multi-Stain Breast Cancer Histological Whole-Slide-Image Data Set from Routine Diagnostics
Weitz, Philippe; Valkonen, Masi; Solorzano, Leslie; Carr, Circe; Kartasalo, Kimmo; Boissin, Constance; Koivukoski, Sonja; Kuusela, Aino; Rasic, Dusan; Feng, Yanbo; Sinius Pouplier, Sandra; Sharma, Abhinav; Ledesma Eriksson, Kajsa; Latonen, Leena; Laenkholm, Anne-Vibeke; Hartman, Johan; Ruusuvuori, Pekka; Rantalainen, Mattias. 2023. Scientific data. 10: . 562 -
Complementary analysis of proteome‐wide proteomics reveals changes in RNA binding protein‐profiles during prostate cancer progression
Aikio, Erika; Koivukoski, Sonja; Kallio, Elina; Sadeesh, Nithin; Niskanen, Einari A; Latonen, Leena. 2023. Cancer reports. [First published: 17 August 2023]: 1-13 -
Deformation equivariant cross-modality image synthesis with paired non-aligned training data
Honkamaa, Joel; Khan, Umair; Koivukoski, Sonja; Valkonen, Mira; Latonen, Leena; Ruusuvuori, Pekka; Marttinen, Pekka. 2023. Medical image analysis. 90: -
Dynamic switching of transcriptional regulators between two distinct low-mobility chromatin states
Wagh, Kaustubh; Stavreva, Diana A.; Jensen, Rikke A. M.; Paakinaho, Ville; Fettweis, Gregory; Schiltz, R. Louis; Wüstner, Daniel; Mandrup, Susanne; Presman, Diego M.; Upadhyaya, Arpita; Hager, Gordon L.. 2023. Science advances. 9: . ade1122 -
Identification of long noncoding RNAs with aberrant expression in prostate cancer metastases
Sattari, Mina; Kohvakka, Annika; Moradi, Elaheh; Rauhala, Hanna; Urhonen, Henna; Isaacs, William B; Nykter, Matti; Murtola, Teemu J; Tammela, Teuvo L. J.; Latonen, Leena; Bova, G. Steven; Kesseli, Juha; Visakorpi, Tapio. 2023. Endocrine-related cancer. 30: -
International Online Team-Based Learning in Higher Education of Biomedicine - Evaluation by Learning Analytics
Mairinoja, Laura; López-Pernas, Sonsoles; Elmoazen, Ramy; Niskanen, Einari A.; Kuningas, Tiina; Wärri, Anni; Saqr, Mohammed; Strauss, Leena. Teoksessa: Elmoazen, Ramy; López-Pernas, Sonsoles; Misiejuk, Kamila; Khalil, Mohammad; Wasson, Barbara; Saqr, Mohammed(toim.) , 2023. Proceedings of the Technology-Enhanced Learning in Laboratories Workshop (TELL 2023). s. 49-60. -
The effect of neural network architecture on virtual H&E staining: Systematic assessment of histological feasibility
Khan, Umair; Koivukoski, Sonja; Valkonen, Mira; Latonen, Leena; Ruusuvuori, Pekka. 2023. Patterns. 4: -
Unstained Tissue Imaging and Virtual Hematoxylin and Eosin Staining of Histologic Whole Slide Images
Koivukoski, Sonja; Khan, Umair; Ruusuvuori, Pekka; Latonen, Leena. 2023. Laboratory investigation. 103: -
Chemical Interrogation of Nuclear Size Identifies Compounds with Cancer Cell Line-Specific Effects on Migration and Invasion
Tollis, Sylvain; Rizzotto, Andrea; Pham, Nhan T; Koivukoski, Sonja; Sivakumar, Aishwarya; Shave, Steven; Wildenhain, Jan; Zuleger, Nikolaj; Keys, Jeremy T; Culley, Jayne; Zheng, Yijing; Lammerding, Jan; Carragher, Neil O; Brunton, Valerie G; Latonen, Leena; Auer, Manfred; Tyers, Mike; Schirmer, Eric C. 2022. Acs chemical biology. 17: 680-700 -
M1 Macrophages Induce Protumor Inflammation in Melanoma Cells through TNFR–NF-κB Signaling
Kainulainen, Kirsi; Takabe, Piia; Heikkinen, Sami; Aaltonen, Niina; de la Motte, Carol; Rauhala, Leena; Durst, Franziska C; Oikari, Sanna; Hukkanen, Taija; Rahunen, Eija; Ikonen, Ella; Hartikainen, Jaana M; Ketola, Kirsi; Pasonen-Seppänen, Sanna. 2022. Journal of investigative dermatology. 1412: 3041-3051.e10