UndeRstanding FITness and Cardiometabolic Health In Little Darlings (urFIT-child)´s Profile image

UndeRstanding FITness and Cardiometabolic Health In Little Darlings (urFIT-child)

Research group
01.01.2020 -
Institute of Public Health and Clinical Nutrition, School of Medicine, Faculty of Health Sciences


Group description

UndeRstanding FITness and Cardiometabolic Health In Little Darlings (urFIT-child) is a multi-disciplinary and multi-collaborative research group in cooperation with renowned global experts across several continents, viz; Oceania, North America, Africa, Europe, and Asia.

The major study outcomes are: arterial stiffness (carotid-femoral pulse wave velocity), carotid intima-media thickness, carotid elasticity or distensibility, left ventricular concentric and eccentric hypertrophy, left ventricular diastolic function, left ventricular filling pressure, etc. These cardiac and vascular outcomes were measured both in adolescence (age 17 years) and young adulthood (age 24 years). Modifiable risk factors are total cholesterol, triglyceride, low-density lipoprotein cholesterol, high-density lipoprotein cholesterol, insulin resistance (glucose and insulin), blood pressure, heart rate, low-grade inflammation, obesity, body composition (fat mass and muscle mass), sedentary time, light physical activity, moderate-to-vigorous physical activity, smoking habit, cardiorespiratory fitness. Risk factors where measured during clinic visit from childhood starting at age 7 years and repeated either yearly or bi-annually until age 17 years. Young adulthood assessments occurred at age 24 years clinic visit, the 30-year clinic visit is currently ongoing (2022 – 2024).

Data and Population Size:

Data for urFIT-child research project are drawn from the Avon Longitudinal Study of Parents and Children (ALSPAC), also known as Children of the 90s, a world-leading UK ongoing birth cohort study. More than 14,000 pregnant women were recruited from April 1991 through December 1992 and 14,901 foetuses arising from the pregnancy, and their partners have been followed up intensively over three decades. The ALSPAC study website contains details of all the data that are available (http://www.bristol.ac.uk/alspac/researchers/our-data/).