Henri Korkalainen

Deep learning‐based prediction of the dose–volume histograms for volumetric modulated arc therapy of left‐sided breast cancer

Leino, Akseli; Heikkilä, Janne; Virén, Tuomas; Honkanen, Juuso TJ.; Seppälä, Jan; Korkalainen, Henri. 2024. Medical physics. 51: 7986-7997 A1 Journal article (refereed), original research

Editorial: Novel technologies in the diagnosis and management of sleep-disordered breathing

Korkalainen, Henri; Zou, Ding. 2024. Frontiers in Sleep. 3: . 1385793 B1 Non-refereed journal articles

Prolonged lung-to-finger circulation time indicates an increased risk of intermittent hypoxaemia in sleep apnoea patients

Pahari, Purbanka; Korkalainen, Henri; Arnardóttir, Erna Sif; Islind, Anna Sigridur; August, Elias; Oksenberg, Arie; Töyräs, Juha; Leppänen, Timo; Nikkonen, Sami. 2024. ERJ open research. 10: . 01051-2023 A1 Journal article (refereed), original research

Respiratory event index underestimates severity of sleep apnea compared to apnea-hypopnea index

Pitkänen, Minna; Nath, Rajdeep Kumar; Korkalainen, Henri; Nikkonen, Sami; Mahamid, Alaa; Oksenberg, Arie; Duce, Brett; Töyräs, Juha; Kainulainen, Samu; Leppänen, Timo. 2024. Sleep advances. 5: . zpad054 A1 Journal article (refereed), original research

Retrospective validation of automatic sleep analysis with grey areas model for human‐in‐the‐loop scoring approach

Rusanen, Matias; Jouan, Gabriel; Huttunen, Riku; Nikkonen, Sami; Sigurðardóttir, Sigríður; Töyräs, Juha; Duce, Brett; Myllymaa, Sami; Arnardottir, Erna Sif; Leppänen, Timo; Islind, Anna Sigridur; Kainulainen, Samu; Korkalainen, Henri. 2024. Journal of sleep research. [First published: 23 October 2024]: 1-13 A1 Journal article (refereed), original research

Sleep stage continuity is associated with objective daytime sleepiness in patients with suspected obstructive sleep apnea

Chen, Xin; Leppänen, Timo; Kainulainen, Samu; Howarth, Timothy P; Oksenberg, Arie; Töyräs, Juha; Terrill, Philip I; Korkalainen, Henri. 2024. Journal of clinical sleep medicine. 20: 1595-1606 A1 Journal article (refereed), original research

Temporal and sleep stage‐dependent agreement in manual scoring of respiratory events

Pitkänen, Minna; Pitkänen, Henna; Nath, Rajdeep Kumar; Nikkonen, Sami; Kainulainen, Samu; Korkalainen, Henri; Ólafsdóttir, Kristín Anna; Arnardottir, Erna Sif; Sigurdardottir, Sigridur; Penzel, Thomas; Fanfulla, Francesco; Anttalainen, Ulla; Saaresranta, Tarja; Grote, Ludger; Hedner, Jan; Staats, Richard; Töyräs, Juha; Leppänen, Timo. 2024. Journal of sleep research. [First published: 04 November 2024]: 1-10 A1 Journal article (refereed), original research

Variation in the Photoplethysmogram Response to Arousal From Sleep Depending on the Cause of Arousal and the Presence of Desaturation

Luukinen, Mieli; Pitkänen, Henna; Leppänen, Timo; Töyräs, Juha; Islind, Anna Sigridur; Kainulainen, Samu; Korkalainen, Henri. 2024. IEEE journal of translational engineering in health and medicine. 12: 328-339 A1 Journal article (refereed), original research

Deep learning-based algorithm accurately classifies sleep stages in preadolescent children with sleep-disordered breathing symptoms and age-matched controls

Somaskandhan, Pranavan; Leppänen, Timo; Terrill, Philip I; Sigurdardottir, Sigridur; Arnardottir, Erna Sif; Ólafsdóttir, Kristín A; Serwatko, Marta; Sigurðardóttir, Sigurveig Þ; Clausen, Michael; Töyräs, Juha; Korkalainen, Henri. 2023. Frontiers in neurology. 14: . 1162998 A1 Journal article (refereed), original research

Generalizable Deep Learning-based Sleep Staging Approach for Ambulatory Textile Electrode Headband Recordings

Rusanen, Matias; Huttunen, Riku; Korkalainen, Henri; Myllymaa, Sami; Toyras, Juha; Myllymaa, Katja; Sigurdardottir, Sigridur; Olafsdottir, Kristin Anna; Leppanen, Timo; Arnardottir, Erna Sif; Kainulainen, Samu. 2023. IEEE journal of biomedical and health informatics. 27: 1869-1880 A1 Journal article (refereed), original research

Morbid obesity influences the nocturnal electrocardiogram wave and interval durations among suspected sleep apnea patients

Kainulainen, Samu; Suni, Aaron; Lipponen, Jukka A; Kulkas, Antti; Duce, Brett; Korkalainen, Henri; Nikkonen, Sami; Sillanmäki, Saara. 2023. Annals of noninvasive electrocardiology. 2024; 29: A1 Journal article (refereed), original research

Multicentre sleep-stage scoring agreement in the Sleep Revolution project

Nikkonen, Sami; Somaskandhan, Pranavan; Korkalainen, Henri; Kainulainen, Samu; Terrill, Philip I; Gretarsdottir, Heidur; Sigurdardottir, Sigridur; Olafsdottir, Kristin Anna; Islind, Anna Sigridur; oskarsdottir, Maria; Arnardottir, Erna Sif; Leppänen, Timo. 2023. Journal of sleep research. 2024; 33: A1 Journal article (refereed), original research

Multi‐centre arousal scoring agreement in the Sleep Revolution

Pitkänen, Henna; Nikkonen, Sami; Rissanen, Marika; Islind, Anna Sigridur; Gretarsdottir, Heidur; Arnardottir, Erna Sif; Leppänen, Timo; Korkalainen, Henri. 2023. Journal of sleep research. 2024; 33: . e14127 A1 Journal article (refereed), original research

Obstructive Sleep Apnea Patients With Atrial Arrhythmias Suffer From Prolonged Recovery From Desaturations

Rissanen, Marika; Korkalainen, Henri; Duce, Brett; Sillanmaki, Saara; Pitkanen, Henna; Suni, Aaron; Nikkonen, Sami; Kulkas, Antti; Toyras, Juha; Leppanen, Timo; Kainulainen, Samu. 2023. IEEE transactions on biomedical engineering. 70: 2122-2130 A1 Journal article (refereed), original research

Reaction time in psychomotor vigilance task is related to hypoxic load in males with sleep apnea

Pahari, Purbanka; Korkalainen, Henri; Karhu, Tuomas; Arnardottir, Erna Sif; Töyräs, Juha; Leppänen, Timo; Nikkonen, Sami. 2023. Journal of sleep research. 2024; 33: A1 Journal article (refereed), original research

Review and perspective on sleep-disordered breathing research and translation to clinics

Korkalainen, Henri; Kainulainen, Samu; Islind, Anna Sigridur; Óskarsdóttir, María; Strassberger, Christian; Nikkonen, Sami; Töyräs, Juha; Kulkas, Antti; Grote, Ludger; Hedner, Jan; Sund, Reijo; Hrubos-Strom, Harald; Saavedra, Jose M.; Ólafsdóttir, Kristín Anna; Ágústsson, Jón S.; Terrill, Philip I.; McNicholas, Walter T.; Arnardóttir, Erna Sif; Leppänen, Timo. 2023. Sleep medicine reviews. 2024; 73: A2 Review article, Literature review, Systematic review

Self‐applied somnography: technical feasibility of electroencephalography and electro‐oculography signal characteristics in sleep staging of suspected sleep‐disordered adults

Rusanen, Matias; Korkalainen, Henri; Gretarsdottir, Heidur; Siilak, Tiina; Olafsdottir, Kristin Anna; Töyräs, Juha; Myllymaa, Sami; Arnardottir, Erna Sif; Leppänen, Timo; Kainulainen, Samu. 2023. Journal of sleep research. 2024; 33: . e13977 A1 Journal article (refereed), original research

Towards a Deeper Understanding of Sleep Stages through their Representation in the Latent Space of Variational Autoencoders

Biedebach, Luka; Rusanen, Matias; Pórðarson, Benedikt Hólm; Arnardóttir, Erna Sif; Óskarsdóttir, María; Nikkonen, Sami; Korkalainen, Henri; Myllymaa, Sami; Töyräs, Juha; Kainulainen, Samu; Leppänen, Timo; Islind, Anna Sigridur. Teoksessa: Bui, Tung(toim.) , 2023. Proceedings of the 56th Annual Hawaii International Conference on System Sciences. s. 3111-3120. Hawaii International Conference on System Sciences A4 Conference proceedings

Translation of obstructive sleep apnea pathophysiology and phenotypes to personalized treatment: a narrative review

McNicholas, Walter T; Korkalainen, Henri. 2023. Frontiers in neurology. 14: . 1239016 A2 Review article, Literature review, Systematic review

A Comparison of Signal Combinations for Deep Learning-Based Simultaneous Sleep Staging and Respiratory Event Detection

Huttunen, Riku; Leppanen, Timo; Duce, Brett; Arnardottir, Erna S.; Nikkonen, Sami; Myllymaa, Sami; Toyras, Juha; Korkalainen, Henri. 2022. IEEE transactions on biomedical engineering. [Date of Publication: 28 November 2022]: 1-12 A1 Journal article (refereed), original research

Deep Learning Enables Accurate Automatic Sleep Staging Based on Ambulatory Forehead EEG

Leino, Akseli; Korkalainen, Henri; Kalevo, Laura; Nikkonen, Sami; Kainulainen, Samu; Ryan, Alexander; Duce, Brett; Sipila, Kirsi; Ahlberg, Jari; Sahlman, Johanna; Miettinen, Tomi; Westeren-Punnonen, Susanna; Mervaala, Esa; Toyras, Juha; Myllymaa, Sami; Leppanen, Timo; Myllymaa, Katja. 2022. IEEE access. 10: 26554-26566 A1 Journal article (refereed), original research

Gamma Power of Electroencephalogram Arousal is Modulated by Respiratory Event Type and Severity in Obstructive Sleep Apnea

Pitkanen, Henna; Duce, Brett; Leppänen, Timo; Kainulainen, Samu; Kulkas, Antti; Myllymaa, Sami; Töyräs, Juha; Korkalainen, Henri. 2022. IEEE transactions on biomedical engineering. 69: 1417-1423 A1 Journal article (refereed), original research

Obstructive sleep apnea‐related intermittent hypoxaemia is associated with impaired vigilance

Pahari, Purbanka; Korkalainen, Henri; Karhu, Tuomas; Rissanen, Marika; Arnardottir, Erna Sif; Hrubos‐Strøm, Harald; Duce, Brett; Töyräs, Juha; Leppänen, Timo; Nikkonen, Sami. 2022. Journal of sleep research. [First published: 08 December 2022]: A1 Journal article (refereed), original research

Pulse Oximetry: The Working Principle, Signal Formation, and Applications

Leppänen, Timo; Kainulainen, Samu; Korkalainen, Henri; Sillanmäki, Saara; Kulkas, Antti; Töyräs, Juha; Nikkonen, Sami. Teoksessa: Penzel, T; Hornero, R(toim.) , 2022. Advances in the Diagnosis and Treatment of Sleep Apnea. s. 205-218. Springer A3 Book section, Chapters in research books

QTc prolongation is associated with severe desaturations in stroke patients with sleep apnea

Sillanmäki, Saara; Lipponen, Jukka A; Korkalainen, Henri; Kulkas, Antti; Leppänen, Timo; Nikkonen, Sami; Töyräs, Juha; Duce, Brett; Suni, Aaron; Kainulainen, Samu. 2022. Bmc pulmonary medicine. 22: . 204 A1 Journal article (refereed), original research

STAR sleep recording export software for automatic export and anonymization of sleep studies

Nikkonen, Sami; Korkalainen, Henri; Töyräs, Juha; Leppänen, Timo. 2022. Scientific reports. 12: . 15859 A1 Journal article (refereed), original research

The severity and morphology of intermittent hypoxemias are related to impaired daytime alertness

Pahari, P; Korkalainen, H; Karhu, T; Rissanen, M; Arnardottir, ES; Strøm, HH; Duce, B; Töyräs, J; Leppänen, T; Nikkonen, S. 2022. Sleep medicine abstract

Automatic Respiratory Event Scoring in Obstructive Sleep Apnea Using a Long Short-Term Memory Neural Network

Nikkonen, Sami; Korkalainen, Henri; Leino, Akseli; Myllymaa, Sami; Duce, Brett; Leppänen, Timo; Töyräs, Juha. 2021. IEEE journal of biomedical and health informatics. 25: 2917-2927 A1 Journal article (refereed), original research

Comparison of EEG Signal Characteristics Between Polysomnography and Self Applied Somnography Setup in a Pediatric Cohort

Kainulainen, Samu; Korkalainen, Henri; Sigurdardottir, Sigriur; Myllymaa, Sami; Serwatko, Marta; Sigurdardottir, Sigurveig Pora; Clausen, Michael; Leppänen, Timo; Arnardottir, Erna Sif. 2021. IEEE access. 9: 110916-110926 A1 Journal article (refereed), original research

Detailed assessment of sleep architecture with deep learning and shorter epoch-to-epoch duration reveals sleep fragmentation of patients with obstructive sleep apnea

Korkalainen, Henri; Leppänen, Timo; Duce, Brett; Kainulainen, Samu; Aakko, Juhani; Leino, Akseli; Kalevo, Laura; Afara, Isaac O; Myllymaa, Sami; Töyräs, Juha. 2021. IEEE journal of biomedical and health informatics. 25: 2567-2574 A1 Journal article (refereed), original research

Neural network analysis of nocturnal SpO2 signal enables easy screening of sleep apnea in patients with acute cerebrovascular disease

Leino, Akseli; Nikkonen, Sami; Kainulainen, Samu; Korkalainen, Henri; Töyräs, Juha; Myllymaa, Sami; Leppänen, Timo; Ylä-Herttuala, Salla; Westeren-Punnonen, Susanna; Muraja-Murro, Anu; Jäkälä, Pekka; Mervaala, Esa; Myllymaa, Katja. 2021. Sleep medicine. 79: 71-78 A1 Journal article (refereed), original research

Self-Applied Home Sleep Recordings: The Future of Sleep Medicine

Korkalainen, Henri; Nikkonen, Sami; Kainulainen, Samu; Dwivedi, Amit Krishna; Myllymaa, Sami; Leppänen, Timo; Töyräs, Juha. 2021. Sleep medicine clinics. 16: 545-556 A2 Review article, Literature review, Systematic review

Technical Performance of Textile-Based Dry Forehead Electrodes Compared With Medical-Grade Overnight Home Sleep Recordings

Rusanen, Matias; Kainulainen, Samu; Korkalainen, Henri; Kalevo, Laura; Myllymaa, Katja; Leppanen, Timo; Toyras, Juha; Arnardottir, Erna Sif; Myllymaa, Sami. 2021. IEEE access. 9: 157902 - 157915 A1 Journal article (refereed), original research

Deep Learning for Next-Generation Sleep Diagnostics: sophisticated computational methods for more efficient and accurate assessment of sleep and obstructive sleep apnea

Korkalainen, Henri. 2020. Publications of the University of Eastern Finland. Dissertations in Forestry and Natural Sciences G5 Doctoral dissertation (article)

Deep learning enables sleep staging from photoplethysmogram for patients with suspected sleep apnea

Korkalainen, H; Aakko, J; Duce, B; Kainulainen, S; Leino, A; Nikkonen, S; Afara, I O; Myllymaa, S; Töyräs, J; Leppänen, T. 2020. Sleep. 43: zsaa098 A1 Journal article (refereed), original research

Effect of sweating on electrode-skin contact impedances and artifacts in EEG recordings with various screen-printed Ag/Agcl electrodes

Kalevo, Laura; Miettinen, Tomi; Leino, Akseli; Kainulainen, Samu; Korkalainen, Henri; Myllymaa, Katja; Töyräs, Juha; Leppänen, Timo; Laitinen, Tiina; Myllymaa, Sami. 2020. IEEE access. 8: 50934-50943 A1 Journal article (refereed), original research

Estimating daytime sleepiness with previous night EEG, EOG and EMG spectrograms in patients with suspected sleep apnea using a convolutional neural network

Nikkonen, Sami; Korkalainen, Henri; Kainulainen, Samu; Myllymaa, Sami; Leino, Akseli; Kalevo, Laura; Oksenberg, Arie; Leppänen, Timo; Töyräs, Juha. 2020. Sleep. 43: zsaa106 A1 Journal article (refereed), original research

Increased nocturnal arterial pulsation frequencies of obstructive sleep apnoea patients is associated with an increased number of lapses in a psychomotor vigilance task

Kainulainen, Samu; Duce, Brett; Korkalainen, Henri; Leino, Akseli; Huttunen, Riku; Kalevo, Laura; Arnardottir, Erna S; Kulkas, Antti; Myllymaa, Sami; Töyräs, Juha; Leppänen, Timo. 2020. ERJ open research. 6: 00277-202 A1 Journal article (refereed), original research

Longer apneas and hypopneas are associated with greater ultra-short-term HRV in obstructive sleep apnea

Hietakoste, Salla; Korkalainen, Henri; Kainulainen, Samu; Sillanmäki, Saara; Nikkonen, Sami; Myllymaa, Sami; Duce, Brett; Töyräs, Juha; Leppänen, Timo. 2020. Scientific reports. 10: 21556 A1 Journal article (refereed), original research

Power spectral densities of nocturnal pulse oximetry signals differ in OSA patients with and without daytime sleepiness

Kainulainen, Samu; Töyräs, Juha; Oksenberg, Arie; Korkalainen, Henri; Afara, Isaac O; Leino, Akseli; Kalevo, Laura; Nikkonen, Sami; Gadoth, Natan; Kulkas, Antti; Myllymaa, Sami; Leppänen, Timo. 2020. Sleep medicine. 73: 231-237 A1 Journal article (refereed), original research

Severe Desaturations Increase PVT-based Median Reaction Time and Number of Lapses in OSA Patients

Kainulainen, S; Duce, B; Korkalainen, H; Oksenberg, A; Leino, A; Arnardottir, E; Kulkas, A; Myllymaa, S; Töyräs, J; Leppänen, T. 2020. European respiratory journal. 55: 1901849 A1 Journal article (refereed), original research

Accurate Deep Learning-Based Sleep Staging in a Clinical Population with Suspected Obstructive Sleep Apnea

Korkalainen, Henri; Aakko, Juhani; Nikkonen, Sami; Kainulainen, Samu; Leino, Akseli; Duce, Brett; Afara, Isaac Oluwaseun; Myllymaa, Sami; Töyräs, Juha; Leppänen, Timo. 2019. IEEE journal of biomedical and health informatics. 24: 2073-2081 A1 Journal article (refereed), original research

Mortality-risk-based apnea-hypopnea index thresholds for diagnostics of obstructive sleep apnea

Korkalainen, H; Töyräs, J; Nikkonen, S; Leppänen, T. 2019. Journal of sleep research. 28: e12855 A1 Journal article (refereed), original research

Severity of desaturations reflects OSA-related daytime sleepiness better than AHI

Kainulainen, S; Töyräs, J; Oksenberg, A; Korkalainen, H; Sefa, S; Kulkas, A; Leppänen, T. 2019. Journal of clinical sleep medicine. 15: 1135-1142 A1 Journal article (refereed), original research

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Deep learning‐based prediction of the dose–volume histograms for volumetric modulated arc therapy of left‐sided breast cancer

Editorial: Novel technologies in the diagnosis and management of sleep-disordered breathing

Prolonged lung-to-finger circulation time indicates an increased risk of intermittent hypoxaemia in sleep apnoea patients

Respiratory event index underestimates severity of sleep apnea compared to apnea-hypopnea index

Retrospective validation of automatic sleep analysis with grey areas model for human‐in‐the‐loop scoring approach

Sleep stage continuity is associated with objective daytime sleepiness in patients with suspected obstructive sleep apnea

Temporal and sleep stage‐dependent agreement in manual scoring of respiratory events

Variation in the Photoplethysmogram Response to Arousal From Sleep Depending on the Cause of Arousal and the Presence of Desaturation

Deep learning-based algorithm accurately classifies sleep stages in preadolescent children with sleep-disordered breathing symptoms and age-matched controls

Generalizable Deep Learning-based Sleep Staging Approach for Ambulatory Textile Electrode Headband Recordings

Morbid obesity influences the nocturnal electrocardiogram wave and interval durations among suspected sleep apnea patients

Multicentre sleep-stage scoring agreement in the Sleep Revolution project

Multi‐centre arousal scoring agreement in the Sleep Revolution

Obstructive Sleep Apnea Patients With Atrial Arrhythmias Suffer From Prolonged Recovery From Desaturations

Reaction time in psychomotor vigilance task is related to hypoxic load in males with sleep apnea

Review and perspective on sleep-disordered breathing research and translation to clinics

Self‐applied somnography: technical feasibility of electroencephalography and electro‐oculography signal characteristics in sleep staging of suspected sleep‐disordered adults

Towards a Deeper Understanding of Sleep Stages through their Representation in the Latent Space of Variational Autoencoders

Translation of obstructive sleep apnea pathophysiology and phenotypes to personalized treatment: a narrative review

A Comparison of Signal Combinations for Deep Learning-Based Simultaneous Sleep Staging and Respiratory Event Detection

Deep Learning Enables Accurate Automatic Sleep Staging Based on Ambulatory Forehead EEG

Gamma Power of Electroencephalogram Arousal is Modulated by Respiratory Event Type and Severity in Obstructive Sleep Apnea

Obstructive sleep apnea‐related intermittent hypoxaemia is associated with impaired vigilance

Pulse Oximetry: The Working Principle, Signal Formation, and Applications

QTc prolongation is associated with severe desaturations in stroke patients with sleep apnea

STAR sleep recording export software for automatic export and anonymization of sleep studies

The severity and morphology of intermittent hypoxemias are related to impaired daytime alertness

Automatic Respiratory Event Scoring in Obstructive Sleep Apnea Using a Long Short-Term Memory Neural Network

Comparison of EEG Signal Characteristics Between Polysomnography and Self Applied Somnography Setup in a Pediatric Cohort

Detailed assessment of sleep architecture with deep learning and shorter epoch-to-epoch duration reveals sleep fragmentation of patients with obstructive sleep apnea

Neural network analysis of nocturnal SpO2 signal enables easy screening of sleep apnea in patients with acute cerebrovascular disease

Self-Applied Home Sleep Recordings: The Future of Sleep Medicine

Technical Performance of Textile-Based Dry Forehead Electrodes Compared With Medical-Grade Overnight Home Sleep Recordings

Deep Learning for Next-Generation Sleep Diagnostics: sophisticated computational methods for more efficient and accurate assessment of sleep and obstructive sleep apnea

Deep learning enables sleep staging from photoplethysmogram for patients with suspected sleep apnea

Effect of sweating on electrode-skin contact impedances and artifacts in EEG recordings with various screen-printed Ag/Agcl electrodes

Estimating daytime sleepiness with previous night EEG, EOG and EMG spectrograms in patients with suspected sleep apnea using a convolutional neural network

Increased nocturnal arterial pulsation frequencies of obstructive sleep apnoea patients is associated with an increased number of lapses in a psychomotor vigilance task

Longer apneas and hypopneas are associated with greater ultra-short-term HRV in obstructive sleep apnea

Power spectral densities of nocturnal pulse oximetry signals differ in OSA patients with and without daytime sleepiness

Severe Desaturations Increase PVT-based Median Reaction Time and Number of Lapses in OSA Patients

Accurate Deep Learning-Based Sleep Staging in a Clinical Population with Suspected Obstructive Sleep Apnea

Mortality-risk-based apnea-hypopnea index thresholds for diagnostics of obstructive sleep apnea

Severity of desaturations reflects OSA-related daytime sleepiness better than AHI