Janne Mäkelä
Academy Research Fellow
Contrast media and biolubricants for early diagnosis and treatment of osteoarthritis.
Department of Technical Physics, Faculty of Science, Forestry and Technology
janne.makela@uef.fi | +358 50 477 1708
Currently interested in contrast media and biolubricants in the early diagnosis and treatment of osteoarthritis. What is the potential of new contrast media in imaging of articular cartilage? How do you best use radiographic imaging to monitor the progression of osteoarthritis over time, and how does a synthetic biopolymer, that lubricates and reinforces the tissue, slow down the disease progression?
Group website
Research groups
Publications
49/49 items-
Advances in viscosupplementation and tribosupplementation for early-stage osteoarthritis therapy
DeMoya, Christian D; Joenathan, Anisha; Lawson, Taylor B; Felson, David T; Schaer, Thomas P; Bais, Manish; Albro, Michael B; Mäkelä, Janne; Snyder, Brian D; Grinstaff, Mark W. 2024. Nature reviews rheumatology. 20: 432-451 A2 Review article, Literature review, Systematic review -
Comparison of site-specific tensile, compressive, and friction properties of human tibiofemoral joint cartilage and their relationship to degeneration
Ristaniemi, Aapo; Tuppurainen, Juuso; Jäntti, Jiri; Nippolainen, Ervin; Afara, Isaac O; Mononen, Mika E; Korhonen, Rami K; Mäkelä, Janne TA. 2024. Journal of biomechanics. 177: A1 Journal article (refereed), original research -
Longitudinal in vivo cationic contrast-enhanced computed tomography classifies equine articular cartilage injury and repair
Nelson, Brad B; Mäkelä, Janne T A; Lawson, Taylor B; Patwa, Amit N; Snyder, Brian D; Mcilwraith, C Wayne; Grinstaff, Mark W; Seabaugh, Kathryn A; Barrett, Myra F; Goodrich, Laurie R; Kawcak, Christopher E. 2024. Journal of orthopaedic research. 42: 2264-2276 A1 Journal article (refereed), original research -
Revealing Detailed Cartilage Function Through Nanoparticle Diffusion Imaging: A Computed Tomography & Finite Element Study
Tuppurainen, Juuso; Paakkari, Petri; Jäntti, Jiri; Nissinen, Mikko T. Fugazzola, Maria C; van Weeren, René; Ylisiurua, Sampo; Nieminen, Miika T; Kröger, Heikki; Snyder, Brian D; Joenathan, Anisha; Grinstaff, Mark W; Matikka, Hanna; Korhonen, Rami K; Mäkelä, Janne TA. 2024. Annals of biomedical engineering. 52: 2584-2595 A1 Journal article (refereed), original research -
3-D T1 relaxation time measurements in an equine model of subtle post-traumatic osteoarthritis using MB-SWIFT
Pala, Swetha; Hänninen, Nina E; Mohammadi, Ali; Ebrahimi, Mohammadhossein; te Moller, Nikae CR; Brommer, Harold; René van Weeren, P; Mäkelä, Janne TA; Korhonen, Rami K; Afara, Isaac O; Töyräs, Juha; Mikkonen, Santtu; Nissi, Mikko J; Nykänen, Olli. 2023. Journal of orthopaedic research. 41: 2657-2666 A1 Journal article (refereed), original research -
Articular Cartilage Characterization Using Tantalum and Iodine-based Dual-Contrast Photon-Counting Computed Tomography
Paakkari, Petri; Inkinen, Satu; Jäntti, Jiri; Tuppurainen, Juuso; Fugazzola, Maria; Joenathan, Anisha; Ylisiurua, Sampo; Nieminen, Miika; Grinstaff, Mark; Kröger, Heikki; Töyräs, Juha; Honkanen, Juuso; Mäkelä, Janne. 2023. Transactions of the annual meeting of the Orthopaedic Research Society abstract -
Cationic tantalum oxide nanoparticle contrast agent for micro computed tomography reveals articular cartilage proteoglycan distribution and collagen architecture alterations
Jäntti, Jiri; Joenathan, Anisha; Fugazzola, Maria; Tuppurainen, Juuso; Honkanen, Juuso TJ; Töyräs, Juha; van Weeren, René; Snyder, Brian D; Grinstaff, Mark W; Matikka, Hanna; Mäkelä, Janne TA. 2023. Osteoarthritis and cartilage. 2024; 32: 299-309 A1 Journal article (refereed), original research -
Composition, architecture and biomechanical properties of articular cartilage in differently loaded areas of the equine stifle
Fugazzola, Maria; Nissinen, Mikko T; Jäntti, Jiri; Tuppurainen, Juuso; Plomp, Saskia; Te Moller, Nikae; Mäkelä, Janne TA; van Weeren, Rene. 2023. Equine veterinary journal. 2024; 56: 573-585 A1 Journal article (refereed), original research -
Contrast Agent Diffusion Reflects Biomechanical Finite Element Model Properties Of Articular Cartilage
Tuppurainen, J; Jäntti, J; Nissinen, MT; Fugazzola, MC; van Weeren, R; Joenathan, A; Grinstaff, MW; Matikka, H; Korhonen, RK; Mäkelä, JT. 2023. Osteoarthritis and cartilage abstract -
Effect Of Depth-dependent Variation In Articular Cartilage Composition On Nanoparticle Diffusion
Jäntti, Jiri; Joenathan, Anisha; Fugazzola, Maria C; van Weeren, René; Synder, Brian D; Grinstaff, Mark W; Töyräs, Juha; Matikka, Hanna; Mäkelä, Janne TA. 2023. Transactions of the annual meeting of the Orthopaedic Research Society abstract