Janne Mäkelä
Academy Research Fellow
Contrast media and biolubricants for early diagnosis and treatment of osteoarthritis.
Department of Technical Physics, Faculty of Science, Forestry and Technology
[email protected] | +358 50 477 1708
Currently interested in contrast media and biolubricants in the early diagnosis and treatment of osteoarthritis. What is the potential of new contrast media in imaging of articular cartilage? How do you best use radiographic imaging to monitor the progression of osteoarthritis over time, and how does a synthetic biopolymer, that lubricates and reinforces the tissue, slow down the disease progression?
Group website
Research groups
Publications
58/58 items-
Contrast‐Enhanced Computed Tomography for Structural and Functional Evaluation of Ligament Microdamage
Tsurayya, Afifah H; Jäntti, Jiri; Paakkari, Petri; Poimala, Milka; Snyder, Brian D; Grinstaff, Mark W; Honkanen, Miitu KM; Mertano, Heta; Ristaniemi, Aapo; Mäkelä, Janne TA, 2026, Journal of orthopaedic research, 44, 2, e70138. A1 Journal article (refereed), original research -
Ultrasmall Surface-Charge-Modified Tantalum Oxide Nanoparticles for the Assessment of Articular Cartilage Using Contrast-Enhanced Computed Tomography
Jäntti, Jiri; Tuppurainen, Juuso; Joenathan, Anisha; Leskinen, Henri P P; Cagnoni, Annunzia M; Mertano, Heta; Poimala, Milka; Nippolainen, Ervin; Afara, Isaac O; Honkanen, Juuso T J; Matikka, Hanna; Töyräs, Juha; Snyder, Brian D; Stok, Kathryn S; Nelson, Brad B; Grinstaff, Mark W; Mäkelä, Janne T A, 2026, Acs nano, 20, 3, 2717-2729. A1 Journal article (refereed), original research -
Calcified Cartilage Mineral Maturity Decreases with Early Osteoarthritis in the Human Knee Joint
Hiltunen, Rasmus K; Turunen, Mikael J; Ristaniemi, Aapo; Nippolainen, Ervin; Afara, Isaac O; Mäkelä, Janne TA; Mononen, Mika E; Tanska, Petri; Honkanen, Juuso TJ, 2025, Transactions of the annual meeting of the Orthopaedic Research Society. Abstract -
Dual-Contrast Agent with Nanoparticle and Molecular Components in Photon-Counting Computed Tomography: Assessing Articular Cartilage Health
Paakkari, Petri; Inkinen, Satu I; Jäntti, Jiri; Tuppurainen, Juuso; Fugazzola, Maria C; Joenathan, Anisha; Ylisiurua, Sampo; Nieminen, Miika T; Kröger, Heikki; Mikkonen, Santtu; van Weeren, René; Snyder, Brian D; Töyräs, Juha; Honkanen, Miitu KM; Matikka, Hanna; Grinstaff, Mark W; Honkanen, Juuso TJ; Mäkelä, Janne TA, 2025, Annals of biomedical engineering, 53, 6, 1423-1438. A1 Journal article (refereed), original research -
Engineering biomimetic zonal properties in fibre-reinforced hydrogels for functional cartilage tissue engineering in vitro
Pahoff, Stephen; Weekes, Angus; Mertano, Heta; Braig, Johannes J; Jones, Michael WM; Maksimenko, Anton; Mäkelä, Janne TA; Tanska, Petri; Korhonen, Rami K; Töyräs, Juha; Hutmacher, Dietmar W; Klein, Travis J; Meinert, Christoph, 2025, Materials today bio, 35, 102550. A1 Journal article (refereed), original research -
Impact of Cationic Nanoparticles and a Neutral Contrast Agent on Articular Cartilage Biomechanics
Rissanen, Maria; Jäntti, Jiri; Tuppurainen, Juuso; Poimala, Milka; Snyder, Brian; Grinstaff, Mark; Mäkelä, Janne, 2025, Osteoarthritis and cartilage. Abstract -
Orientation-Independent T2 Mapping Enhances MRI-Based Cartilage Characterization
Leskinen, Henri P P; Tuppurainen, Juuso; Jäntti, Jiri; Mäkelä, Janne T A; Nippolainen, Ervin; Afara, Isaac O; Töyräs, Juha; Nykänen, Olli; Nissi, Mikko J, 2025, Annals of biomedical engineering, 53, 9, 2120-2130. A1 Journal article (refereed), original research -
Relationships between human patellar tendon and tibial cartilage viscoelastic properties in osteoarthritic knees: an exploratory investigation
Kositsky, Adam; Linus, Awuniji; Stenroth, Lauri; Nippolainen, Ervin; Kröger, Heikki; Töyräs, Juha; Mäkelä, Janne TA; Liukkonen, Mimmi K; Tanska, Petri; Afara, Isaac O; Mononen, Mika E; Korhonen, Rami K, 2025, Journal of biomechanics, 189, 112772. A1 Journal article (refereed), original research -
The human patellar tendon is mechanically homogenous at its mid-substance
Kositsky, Adam; Stenroth, Lauri; Nippolainen, Ervin; Torniainen, Jari; Mäkelä, Janne TA; Paakkari, Petri; Paakkonen, Tommi; Kröger, Heikki; Töyräs, Juha; Afara, Isaac O; Korhonen, Rami K, 2025, Journal of the mechanical behavior of biomedical materials, 163, 106875. A1 Journal article (refereed), original research -
Advances in viscosupplementation and tribosupplementation for early-stage osteoarthritis therapy
DeMoya, Christian D; Joenathan, Anisha; Lawson, Taylor B; Felson, David T; Schaer, Thomas P; Bais, Manish; Albro, Michael B; Mäkelä, Janne; Snyder, Brian D; Grinstaff, Mark W, 2024, Nature reviews rheumatology, 20, 432-451. A2 Review article, Literature review, Systematic review