Jiajia Wang
Doctoral Researcher
Development of bioinspired nano vaccines with silica nanoparticles
Department of Technical Physics, Faculty of Science, Forestry and Technology
[email protected] | +358 50 472 6341
I aim to deepen the understanding of the mechanism of interaction between nanoparticles and immune cells, improve the antigen delivery efficiency for immunotherapy, and address the challenges of poor cancer targeting, low therapy efficiency, and the inability to treat cancer metastasis with biomimetic nanoparticles, which are carried out by coating the nanoparticles with cancer cell membranes.
Research groups
Publications
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Drug-Free Approach to Regulate Undruggable Proto-Oncogene MYC Using Biomimetic Porous Nanoparticles for Cancer Immunotherapy
Happonen, Emilia; Dang, Yijing; Wang, Jiajia; Saarela, Silja; Sivonen, Minna; Zakir, Mohammed; Laari, Milla-Iida; Constantinou, Yiannis; Tamarov, Konstantin; Hakkarainen, Henri; Montaser, Ahmed Bisher; Leinonen, Henri; Küblbeck, Jenni; Örd, Tiit; Taipale, Mari; Kaikkonen, Minna; Liu, Ruixian; Klefström, Juha; Yu, Haijun; Xu, Zhiai; Lehto, Vesa-Pekka; Xu, Wujun, 2025, Acs applied materials and interfaces, 17, 33, 46521-46534. A1 Journal article (refereed), original research -
Mechanism of biomimetic virus-like nanoparticles in triggering immune response elucidated by proteomics
Wang, Jiajia; Montaser, Ahmed; Sivonen, Minna; Leinonen, Henri; Nygård, Lucas; Kinnunen, Tuure; Pitkänen, Sini; Levonen-Harju, Anna-Liisa; Batnasan, Enkhzaya; Latonen, Leena; Hepojoki, Jussi; Ma, Leyuan; Lehto, Vesa-Pekka; Xu, Wujun, 2025, Colloids and surfaces b: biointerfaces, 259, 115338. A1 Journal article (refereed), original research