My PhD project research focuses on the roles of hepatocyte- and adipose tissue-derived extracellular vesicles in the development and progression of non-alcoholic fatty liver disease (NAFLD).
Research groups
Publications
7/7 items-
Increased secretion of adipocyte-derived extracellular vesicles is associated with adipose tissue inflammation and the mobilization of excess lipid in human obesity
Matilainen, Johanna; Berg, Viivi; Vaittinen, Maija; Impola, Ulla; Mustonen, Anne-Mari; Männistö, Ville; Malinen, Marjo; Luukkonen, Veera; Rosso, Natalia; Turunen, Tanja; Käkelä, Pirjo; Palmisano, Silvia; Arasu, Uma Thanigai; Sihvo, Sanna P.; Aaltonen, Niina; Härkönen, Kai; Caddeo, Andrea; Kaminska, Dorota; Pajukanta, Päivi; Kaikkonen, Minna U.; Tiribelli, Claudio; Käkelä, Reijo; Laitinen, Saara; Pihlajamäki, Jussi; Nieminen, Petteri; Rilla, Kirsi. 2024. Journal of translational medicine. 22: . 623 A1 Journal article (refereed), original research -
Fatty Acid Fingerprints and Hyaluronic Acid in Extracellular Vesicles from Proliferating Human Fibroblast-like Synoviocytes
Mustonen, Anne-Mari; Paakkonen, Tommi; Matilainen, Johanna; Rilla, Kirsi; Käkelä, Reijo; Malinen, Marjo; Takabe, Piia; Oikari, Sanna; Capra, Janne; Sihvo, Sanna P; Ryökäs, Pauliina; Nieminen, Petteri. 2022. International journal of molecular sciences. 23: A1 Journal article (refereed), original research -
MCF10CA Breast Cancer Cells Utilize Hyaluronan-Coated EV-Rich Trails for Coordinated Migration
Aaltonen, Niina; Kyykallio, Heikki; Tollis, Sylvain; Capra, Janne; Hartikainen, Jaana M.; Matilainen, Johanna; Oikari, Sanna; Rilla, Kirsi. 2022. Frontiers in oncology. 12: . 869417 A1 Journal article (refereed), original research -
Characterization of hyaluronan-coated extracellular vesicles in synovial fluid of patients with osteoarthritis and rheumatoid
Mustonen, Anne-Mari; Capra, Janne; Rilla, Kirsi; Lehenkari, Petri; Oikari, Sanna; Kääriäinen, Tommi; Joukainen, Antti; Kröger, Heikki; Paakkonen, Tommi; Matilainen, Johanna; Nieminen, Petteri. 2021. Bmc musculoskeletal disorders. 22: 247 A1 Journal article (refereed), original research -
Orotic acid-treated hepatocellular carcinoma cells resist steatosis by modification of fatty acid metabolism
Matilainen, Johanna; Mustonen, Anne-Mari; Rilla, Kirsi; Käkelä, Reijo; Sihvo, Sanna; Nieminen, Petteri. 2020. Lipids in health and disease. 19: 70 A1 Journal article (refereed), original research -
Extracellular vesicles are integral and functional components of the extracellular matrix
Rilla, Kirsi; Mustonen, Anne-Mari; Thanigai, Arasu Uma; Härkönen, Kai; Matilainen, Johanna; Nieminen, Petteri. 2019. Matrix biology. 75-76: 201-219 A2 Review article, Literature review, Systematic review -
Hyaluronan histochemistry - A potential new tool to assess the progress of liver disease from simple steatosis to hepatocellular carcinoma
Mustonen, Anne-Mari; Salvén, Anu; Kärjä, Vesa; Rilla, Kirsi; Matilainen, Johanna; Nieminen, Petteri. 2019. Glycobiology. 29: 298-306 A1 Journal article (refereed), original research