Jouni Härkönen
Research groups
Publications
9/9 items-
Comprehensive characterization of micropapillary colorectal adenocarcinoma
Äijälä, Ville K; Härkönen, Jouni; Mantere, Tuomo; Elomaa, Hanna; Sirniö, Päivi; Pohjanen, Vesa‐Matti; Sirkiä, Onni; Karjalainen, Henna; Kastinen, Meeri; Tapiainen, Vilja V; Väyrynen, Sara A; Pölönen, Petri; Ahtiainen, Maarit; Helminen, Olli; Wirta, Erkki‐Ville; Rintala, Jukka; Meriläinen, Sanna; Saarnio, Juha; Rautio, Tero; Pylkäs, Katri; Seppälä, Toni T; Böhm, Jan; Mecklin, Jukka‐Pekka; Tuomisto, Anne; Mäkinen, Markus J; Väyrynen, Juha P. 2025. Journal of pathology. [First published: 07 February 2025]: 1-14 A1 Journal article (refereed), original research -
Oncogenic KEAP1 mutations activate TRAF2-NFκB signaling to prevent apoptosis in lung cancer cells
Deen, Ashik Jawahar; Adinolfi, Simone; Härkönen, Jouni; Patinen, Tommi; Liu, Xiaonan; Laitinen, Tuomo; Takabe, Piia; Kainulainen, Kirsi; Pasonen-Seppänen, Sanna; Gawriyski, Lisa M; Arasu, Uma Thanigai; Selvarajan, Ilakya; Mäkinen, Petri; Laitinen, Hanna; Kansanen, Emilia; Kaikkonen, Minna U; Poso, Antti; Varjosalo, Markku; Levonen, Anna-Liisa. 2024. Redox biology. 69: A1 Journal article (refereed), original research -
Quantitative Multiplexed Analysis of Indoleamine 2,3-Dioxygenase (IDO) and Arginase-1 (ARG1) Expression and Myeloid Cell Infiltration in Colorectal Cancer
Elomaa, Hanna; Härkönen, Jouni; Väyrynen, Sara A; Ahtiainen, Maarit; Ogino, Shuji; Nowak, Jonathan A; Lau, Mai Chan; Helminen, Olli; Wirta, Erkki Ville; Seppälä, Toni T; Böhm, Jan; Mecklin, Jukka Pekka; Kuopio, Teijo; Väyrynen, Juha P. 2024. Modern pathology. 37: . 100450 A1 Journal article (refereed), original research -
A pan-cancer analysis shows immunoevasive characteristics in NRF2 hyperactive squamous malignancies
Härkönen, Jouni; Pölönen, Petri; Deen, Ashik Jawahar; Selvarajan, Ilakya; Teppo, Hanna-Riikka; Dimova, Elitsa Y.; Kietzmann, Thomas; Ahtiainen, Maarit; Väyrynen, Juha P.; Väyrynen, Sara A.; Elomaa, Hanna; Tynkkynen, Niko; Eklund, Tiia; Kuopio, Teijo; Talvitie, Eva-Maria; Taimen, Pekka; Kallajoki, Markku; Kaikkonen, Minna U.; Heinäniemi, Merja; Levonen, Anna-Liisa. 2023. Redox biology. 61: A1 Journal article (refereed), original research -
Single-cell functional genomics reveals determinants of sensitivity and resistance to natural killer cells in blood cancers
Dufva, Olli; Gandolfi, Sara; Huuhtanen, Jani; Dashevsky, Olga; Duàn, Hanna; Saeed, Khalid; Klievink, Jay; Nygren, Petra; Bouhlal, Jonas; Lahtela, Jenni; Näätänen, Anna; Ghimire, Bishwa R.; Hannunen, Tiina; Ellonen, Pekka; Lähteenmäki, Hanna; Rumm, Pauliina; Theodoropoulos, Jason; Laajala, Essi; Härkönen, Jouni; Pölönen, Petri; Heinäniemi, Merja; Hollmén, Maija; Yamano, Shizuka; Shirasaki, Ryosuke; Barbie, David A.; Roth, Jennifer A.; Romee, Rizwan; Sheffer, Michal; Lähdesmäki, Harri; Lee, Dean A. 2023. Immunity. 56: 2816-2835.e13 A1 Journal article (refereed), original research -
The KEAP1-NRF2 pathway: Targets for therapy and role in cancer
Adinolfi, Simone; Patinen, Tommi; Jawahar Deen, Ashik; Pitkänen, Sini; Härkönen, Jouni; Kansanen, Emilia; Küblbeck, Jenni; Levonen, Anna-Liisa. 2023. Redox biology. 63: A2 Review article, Literature review, Systematic review -
A novel uterine leiomyoma subtype exhibits NRF2 activation and mutations in genes associated with neddylation of the Cullin 3-RING E3 ligase
Mehine, Miika; Ahvenainen, Terhi; Khamaiseh, Sara; Härkönen, Jouni; Reinikka, Siiri; Heikkinen, Tuomas; Äyräväinen, Anna; Pakarinen, Päivi; Härkki, Päivi; Pasanen, Annukka; Levonen, Anna-Liisa; Bützow, Ralf; Vahteristo, Pia. 2022. Oncogenesis. 11: . 52 A1 Journal article (refereed), original research -
Regulation of stress signaling pathways by protein lipoxidation
Patinen, Tommi; Adinolfi, Simone; Cortés, Carlos Cruz; Härkönen, Jouni; Jawahar Deen, Ashik; Levonen, Anna-Liisa. 2019. Redox biology. 23: 1-8 A2 Review article, Literature review, Systematic review -
Regulation of stress signaling pathways by nitro-fatty acids
Deen, Ashik Jawahar; Sihvola, Virve; Härkönen, Jouni; Patinen, Tommi; Adinolfi, Simone; Levonen, Anna-Liisa. 2018. Nitric oxide-biology and chemistry. 78: 170-175 A2 Review article, Literature review, Systematic review